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MMDB Description
54950Altering the Mouth of a Hydrophobic Pocket. Structure and Kinetics of Human Carbonic Anhydrase II Mutants at Residue Val-121
55041Human Carbonic Anhydrase II Complexed With Brinzolamide
47912Carbonic Anhydrase II Inhibitor: Acetohydroxamate
48012Human Carbonic Anhydrase II Complexed With the Histamine Activator
48110X-ray Crystallographic Structure of a Complex Between Human Carbonic Anhydrase II and a NEW Topical Inhibitor, Trifluoromethane Sulphonamide
48178Crystallographic Analysis of Thr-200-> HIS Human Carbonic Anhydrase II and ITS Complex With the Substrate, Hco3-
54909Carbonic Anhydrase II Inhibitor
54910Carbonic Anhydrase II Inhibitor
54911Carbonic Anhydrase II Inhibitor
54912Carbonic Anhydrase II Inhibitor
54913Carbonic Anhydrase II Inhibitor
55614Carbonic Anhydrase II Inhibitor
55616Carbonic Anhydrase II Inhibitor
55617Carbonic Anhydrase II Inhibitor
48223Carbonic Anhydrase II Inhibitor
48224Carbonic Anhydrase II Inhibitor
48272Human Carbonic Anhydrase II Complexed With Urea
55698Refined Structure of Human Carbonic Anhydrase II at 2.0 Angstroms Resolution
55699Unexpected Ph-dependent Conformation of His-64, the Proton Shuttle of Carbonic Anhydrase II
48329Structure of Cobalt Carbonic Anhydrase Complexed With Bicarbonate
48330Structural Analysis of the Zinc Hydroxide-thr 199-glu 106 Hydrogen Bonding Network in Human Carbonic Anhydrase II
48331Structural Analysis of the Zinc Hydroxide-thr 199-glu 106 Hydrogen Bonding Network in Human Carbonic Anhydrase II
48332Structural Analysis of the Zinc Hydroxide-thr 199-glu 106 Hydrogen Bonding Network in Human Carbonic Anhydrase II
48333Structural Analysis of the Zinc Hydroxide-thr 199-glu 106 Hydrogen Bonding Network in Human Carbonic Anhydrase II
48334Structural Analysis of the Zinc Hydroxide-thr 199-glu 106 Hydrogen Bonding Network in Human Carbonic Anhydrase II
86709Crystallographic Studies of the Binding of Protonated and Unprotonated Inhibitors to Carbonic Anhydrase Using Hydrogen Sulphide and Nitrate Anions
86710Crystallographic Studies of the Binding of Protonated and Unprotonated Inhibitors to Carbonic Anhydrase Using Hydrogen Sulphide and Nitrate Anions
48339Wild-type and E106q Mutant Carbonic Anhydrase Complexed With Acetate
48340Wild-type and E106q Mutant Carbonic Anhydrase Complexed With Acetate
55725Structure-assisted Redesign of a Protein-zinc Binding Site With Femtomolar Affinity
55726Structure-assisted Redesign of a Protein-zinc Binding Site With Femtomolar Affinity
55727Structure-assisted Redesign of a Protein-zinc Binding Site With Femtomolar Affinity
48375The Positions of His-64 and a Bound Water in Human Carbonic Anhydrase II Upon Binding Three Structurally Related Inhibitors
48376The Positions of His-64 and a Bound Water in Human Carbonic Anhydrase II Upon Binding Three Structurally Related Inhibitors
48377The Positions of His-64 and a Bound Water in Human Carbonic Anhydrase II Upon Binding Three Structurally Related Inhibitors
55788Compensatory Plastic Effects in the Redesign of Protein- Zinc Binding Sites
55789Compensatory Plastic Effects in the Redesign of Protein- Zinc Binding Sites
55792X-ray Crystallographic Studies of Engineered Hydrogen Bond Networks in a Protein-zinc Binding Site
55793X-ray Crystallographic Studies of Engineered Hydrogen Bond Networks in a Protein-zinc Binding Site
55794X-ray Crystallographic Studies of Engineered Hydrogen Bond Networks in a Protein-zinc Binding Site
55795X-ray Crystallographic Studies of Engineered Hydrogen Bond Networks in a Protein-zinc Binding Site
55796X-ray Crystallographic Studies of Engineered Hydrogen Bond Networks in a Protein-zinc Binding Site
55799Secondary Interactions Significantly Removed From the Sulfonamide Binding Pocket of Carbonic Anhydrase II Influence Binding Constants
55800Secondary Interactions Significantly Removed From the Sulfonamide Binding Pocket of Carbonic Anhydrase II Influence Binding Constants
55801Secondary Interactions Significantly Removed From the Sulfonamide Binding Pocket of Carbonic Anhydrase II Influence Binding Constants
86715The Complex Between Human Carbonic Anhydrase II and the Aromatic Inhibitor 1,2,4-triazole
55859Structural and Functional Importance of a Conserved Hydrogen Bond Network in Human Carbonic Anhydrase II
55860Structural and Functional Importance of a Conserved Hydrogen Bond Network in Human Carbonic Anhydrase II
55861Redesigning the Zinc Binding Site of Human Carbonic Anhydrase II: Structure of a His2asp-zn2+ Metal Coordination Polyhedron
55862Structural Consequences of Redesigning a Protein-zinc Binding Site
55863Structural Consequences of Redesigning a Protein-zinc Binding Site
55864Structural Consequences of Redesigning a Protein-zinc Binding Site
55865Structural Consequences of Redesigning a Protein-zinc Binding Site
55900Structure of an Engineered Metal Binding Site in Human Carbonic Anhydrase II Reveals the Architecture of a Regulatory Cysteine Switch
55901Structure of an Engineered Metal Binding Site in Human Carbonic Anhydrase II Reveals the Architecture of a Regulatory Cysteine Switch
18634Crystal Structure of Human Carbonic Anhydrase II Complexed With an Anticonvulsant Sugar Sulfamate
13691The Mechanism of Cyanamide Hydration Catalyzed by Carbonic Anhydrase II Revealed by Cryogenic X-ray Diffraction
15407X-ray Crystal Structure of Zinc-bound F95mw97v Carbonic Anhydrase (Caii) Variant
15408X-ray Crystal Structure of Zinc-bound F93if95mw97v Carbonic Anhydrase (Caii) Variant
15409X-ray Crystal Structure of Metal-free F93if95mw97v Carbonic Anhydrase (Caii) Variant
15410X-ray Crystal Structure of Cobalt-bound F93if95mw97v Carbonic Anhydrase (Caii) Variant
15413X-ray Crystal Structure of Copper-bound F93if95mw97v Carbonic Anhydrase (Caii) Variant
15415X-ray Crystal Structure of Zinc-bound F93sf95lw97m Carbonic Anhydrase (Caii) Variant
15419X-ray Crystal Structure of Metal-free F93sf95lw97m Carbonic Anhydrase (Caii) Variant
15420X-ray Crystal Structure of Cobalt-bound F93sf95lw97m Carbonic Anhydrase (Caii) Variant
15421X-ray Crystal Structure of Copper-bound F93sf95lw97m Carbonic Anhydrase (Caii) Variant
14869Site-specific Mutant (His64 Replaced With Ala) of Human Carbonic Anhydrase II Complexed With 4-methylimidazole
14870Site-specific Mutant (His64 Replaced With Ala) of Human Carbonic Anhydrase II
14650Carbonic Anhydrase II Complexed With 4-(aminosulfonyl)-n- [(2-fluorophenyl)methyl]-benzamide
14653Carbonic Anhydrase II (F131v)
14654Carbonic Anhydrase II (F131v) Complexed With 4- (Aminosulfonyl)-n-[(2-fluorophenyl)methyl]-benzamide
14655Carbonic Anhydrase II (F131v) Complexed With 4- (Aminosulfonyl)-n-[(2,3-difluorophenyl)methyl]-benzamide
14656Carbonic Anhydrase II (F131v) Complexed With 4- (Aminosulfonyl)-n-[(2,6-difluorophenyl)methyl]-benzamide
14658Carbonic Anhydrase II (F131v) Complexed With 4- (Aminosulfonyl)-n-[(2,3,4,5,6-pentafluorophenyl)methyl]- Benzamide
14659Carbonic Anhydrase II (F131v) Complexed With 4- (Aminosulfonyl)-n-phenylmethylbenzamide
14660Carbonic Anhydrase II Complexed With 4-(aminosulfonyl)-n- [(2,3-difluorophenyl)methyl]-benzamide
14661Carbonic Anhydrase II Complexed With 4-(aminosulfonyl)-n- [(2,6-difluorophenyl)methyl]-benzamide
14662Carbonic Anhydrase II Complexed With 4-(aminosulfonyl)-n- [(2,3,4,5,6-pentafluorophenyl)methyl]-benzamide
14557Complex of the Camelid Heavy-chain Antibody Fragment Cab- Ca05 With Bovine Carbonic Anhydrase
56286H94n Carbonic Anhydrase II Complexed With Tris
56287H119n Carbonic Anhydrase II
56288H119q Carbonic Anhydrase II
56303Unexpected Ph-dependent Conformation of His-64, the Proton Shuttle of Carbonic Anhydrase II
56314Carbonic Anhydrase II (Carbonate Dehydratase) (Hca II) (E.c.4.2.1.1) Mutant With LEU 198 Replaced by ARG (L198r)
56315Structural Consequences of Hydrophilic Amino-acid Substitutions in the Hydrophobic Pocket of Human Carbonic Anhydrase II
56316Structural Consequences of Hydrophilic Amino-acid Substitutions in the Hydrophobic Pocket of Human Carbonic Anhydrase II
56317Structural Consequences of Hydrophilic Amino-acid Substitutions in the Hydrophobic Pocket of Human Carbonic Anhydrase II
56392Engineering the Zinc Binding Site of Human Carbonic Anhydrase II: Structure of the His-94-> CYS Apoenzyme in a NEW Crystalline Form
15851Carbonic Anhydrase II Complexed With Al-6629 2h-thieno[3,2- E]-1,2-thiazine-6-sulfonamide, 2-(3-methoxyphenyl)-3-(4- Morpholinyl)-, 1,1-dioxide
15852Carbonic Anhydrase II Complexed With Al-8520 2h-thieno[3,2- E]-1,2-thiazine-6-sulfonamide, 4-amino-3,4-dihydro-2-(3- Methoxypropyl)-, 1,1-dioxide, (R)
15853Carbonic Anhydrase II Complexed With Al-6619 2h-thieno[3,2- E]-1,2-thiazine-6-sulfonamide, 2-(3-hydroxyphenyl)-3-(4- Morpholinyl)-, 1,1-dioxide
15855Carbonic Anhydrase II (F131v) Complexed With 4- (Aminosulfonyl)-n-[(4-fluorophenyl)methyl]-benzamide
15856Carbonic Anhydrase II (F131v) Complexed With 4- (Aminosulfonyl)-n-[(2,4-difluorophenyl)methyl]-benzamide
15857Carbonic Anhydrase II (F131v) Complexed With 4- (Aminosulfonyl)-n-[(2,5-difluorophenyl)methyl]-benzamide
15858Carbonic Anhydrase II (F131v) Complexed With 4- (Aminosulfonyl)-n-[(2,3,4-trifluorophenyl)methyl]-benzamide
15859Carbonic Anhydrase II (F131v) Complexed With 4- (Aminosulfonyl)-n-[(2,4,6-trifluorophenyl)methyl]-benzamide
15860Carbonic Anhydrase II (F131v) Complexed With 4- (Aminosulfonyl)-n-[(3,4,5-trifluorophenyl)methyl]-benzamide
16176Carbonic Anhydrase II Complexed With 4- Fluorobenzenesulfonamide
16177Carbonic Anhydrase II Complexed With 2,6- Difluorobenzenesulfonamide
16178Carbonic Anhydrase II Complexed With 3,5- Difluorobenzenesulfonamide
16179Carbonic Anhydrase II Complexed With (R)-n-(3-indol-1-yl-2- Methyl-propyl)-4-sulfamoyl-benzamide
16180Carbonic Anhydrase II Complexed With (S)-n-(3-indol-1-yl-2- Methyl-propyl)-4-sulfamoyl-benzamide
16181Carbonic Anhydrase II Complexed With N-[2-(1h-indol-5-yl)- Butyl]-4-sulfamoyl-benzamide
21687Human Carbonic Anhydrase II Complexed With Inhibitor 2000-07
21688Human Carbonic Anhydrase II Complexed With Inhibitor 0134-36
20231Crystal Structure Analysis of the HCA II Mutant T199p in Complex With Beta-mercaptoethanol
20232Crystal Structure Analysis of HCA II Mutant T199p in Complex With Thiocyanate
20233Crystal Structure Analysis of HCA II Mutant T199p in Complex With Bicarbonate
23737Full Matrix Error Analysis of Carbonic Anhydrase
20937Site-specific Mutant (Tyr7 Replaced With His) of Human Carbonic Anhydrase II
20751Site Specific Mutant (H64a) of Human Carbonic Anhydrase II at High Resolution
56907Structure and Energetics of a Non-proline Cis-peptidyl Linkage in an Engineered Protein
50647Carbonic Anhydrase II Complex With the 1okl Inhibitor 5- Dimethylamino-naphthalene-1-sulfonamide
57032Carbonic Anhydrase II Complex With the 1okm Inhibitor 4- Sulfonamide-[1-(4-aminobutane)]benzamide
57033Carbonic Anhydrase II Complex With the 1okn Inhibitor 4- Sulfonamide-[1-(4-n-(5-fluorescein Thiourea)butane)]
26784Carbonic Anhydrase II in Complex With Nanomolar Inhibitor
51127The Structure of Human Carbonic Anhydrase II in Complex With Bromide and Azide
51128The Structure of Human Carbonic Anhydrase II in Complex With Bromide and Azide
51251X-ray Analysis of Metal Substituted Human Carbonic Anhydrase II Derivatives
51252X-ray Analysis of Metal Substituted Human Carbonic Anhydrase II Derivatives
51253X-ray Analysis of Metal Substituted Human Carbonic Anhydrase II Derivatives
51254X-ray Analysis of Metal Substituted Human Carbonic Anhydrase II Derivatives
51255X-ray Analysis of Metal Substituted Human Carbonic Anhydrase II Derivatives
31249Effect of Shuttle Location and PH Environment on H+ Transfer in Human Carbonic Anhydrase II
31250Effect of Shuttle Location and PH Environment on H+ Transfer in Human Carbonic Anhydrase II
31252Effect of Shuttle Location and PH Environment on H+ Transfer in Human Carbonic Anhydrase II
31254Effect of Shuttle Location and PH Environment on H+ Transfer in Human Carbonic Anhydrase II
31255Effect of Shuttle Location and PH Environment on H+ Transfer in Human Carbonic Anhydrase II
31256Effect of Shuttle Location and PH Environment on H+ Transfer in Human Carbonic Anhydrase II
31257Effect of Shuttle Location and PH Environment on H+ Transfer in Human Carbonic Anhydrase II
31258Effect of Shuttle Location and PH Environment on H+ Transfer in Human Carbonic Anhydrase II
31259Effect of Shuttle Location and PH Environment on H+ Transfer in Human Carbonic Anhydrase II
31260Effect of Shuttle Location and PH Environment on H+ Transfer in Human Carbonic Anhydrase II
29477Human Carbonic Anhydrase II Complexed With 667-coumate
57551Human Carbonic Anhydrase Ii[hcaii] (E.c.4.2.1.1) Mutant With ALA 65 Replaced by PHE (A65f)
57552Human Carbonic Anhydrase Ii[hcaii] (E.c.4.2.1.1) Mutant With ALA 65 Replaced by GLY (A65g)
57553Human Carbonic Anhydrase II [hcaii] (E.c.4.2.1.1) Mutant With ALA 65 Replaced by HIS (A65h)
57554Human Carbonic Anhydrase Ii[hcaii] (E.c.4.2.1.1) Mutant With ALA 65 Replaced by SER (A65s)
57555Human Carbonic Anhydrase II [hcaii] (E.c.4.2.1.1) Mutant With ALA 65 Replaced by LEU (A65l)
57556Human Carbonic Anhydrase II [hcaii] (E.c.4.2.1.1) Mutant With ALA 65 Replaced by THR (A65t)
57557Human Carbonic Anhydrase Ii[hcaii] (E.c.4.2.1.1) Mutant With ALA 65 Replaced by SER (A65s)-orthorhombic Form
35028Crystal Structure of Human Carbonic Anhydrase II Complexed W Acetate Ion
35030Crystal Structure of Human Carbonic Anhydrase II in a NEW Crystal Form
33333Structure of Human Carbonic Anhydrase II With 4-[4-o- Sulfamoylbenzyl)(4-cyanophenyl)amino]-4h-[1,2,4]-triazole
33334Structure of Human Carbonic Anhydrase II With 4-[(3-bromo-4- O-sulfamoylbenzyl)(4-cyanophenyl)amino]-4h-[1,2,4]-triazole
57719Structural Basis of Inhibitor Affinity to Variants of Human Carbonic Anhydrase II
57720Structural Basis of Inhibitor Affinity to Variants of Human Carbonic Anhydrase II
57721Structural Basis of Inhibitor Affinity to Variants of Human Carbonic Anhydrase II
57722Structural Basis of Inhibitor Affinity to Variants of Human Carbonic Anhydrase II
35073Proton Transfer From His200 in Human Carbonic Anhydrase II
35074Proton Transfer From His200 in Human Carbonic Anhydrase II
35075Proton Transfer From His200 in Human Carbonic Anhydrase II
38943Carbonic Anhydrase II in Complex With Furosemide as Sulfonamide Inhibitor
35545Carbonic Anhydrase II in Complex With a Membrane-impermeant Sulfonamide Inhibitor
38944Carbonic Anhydrase II in Complex With N-4-sulfonamidphenyl-n'-4- Methylbenzosulfonylurease as Sulfonamide Inhibitor
38945Carbonic Anhydrase II in Complex With Ethoxzolamidphenole as Sulfonamide Inhibitor
38946Carbonic Anhydrase II in Complex With P-sulfonamido-o,o'- Dichloroaniline as Sulfonamide Inhibitor
38947Carbonic Anhydrase II in Complex With Trichloromethiazide as Sulfonamide Inhibitor
38948Carbonic Anhydrase II in Complex With N-4-methyl-1- Piperazinyl-n'-(p-sulfonamide)phenylthiourea as Sulfonamide Inhibitor
57773Carbonic Anhydrase II Mutant E117q, APO Form
57774Carbonic Anhydrase II Mutant E117q, Transition State Analogue Acetazolamide
57775Carbonic Anhydrase II Mutant E117q, Holo Form
35598Carbonic Anhydrase Activators: X-ray Crystal Structure of the Adduct of Human Isozyme II With L-histidine as a Platform for the Design of Stronger Activators
39580Carbonic Anhydrase Inhibitors: Valdecoxib Binds to a Different Active Site Region of the Human Isoform II as Compared to the Structurally Related Cyclooxygenase II "selective" Inhibitor Celecoxib
36693Production and X-ray Crystallographic Analysis of Fully Deuterated Human Carbonic Anhydrase II
57907Crystallographic Studies of Inhibitor Binding Sites in Human Carbonic Anhydrase II. a Pentacoordinated Binding of the Scn-ion to the Zinc at High PH
86932Structure of Native and APO Carbonic Anhydrase II and Some of ITS Anion-ligand Complexes
86933Structure of Native and APO Carbonic Anhydrase II and Some of ITS Anion-ligand Complexes
86934Structure of Native and APO Carbonic Anhydrase II and Some of ITS Anion-ligand Complexes
86935Structure of Native and APO Carbonic Anhydrase II and Some of ITS Anion-ligand Complexes
74554Structure of Native and APO Carbonic Anhydrase II and Some of ITS Anion-ligand Complexes
40381Human Carbonic Anhydrase II in Complex With Novel Inhibitors
40382Human Carbonic Anhydrase II in Complex With Novel Inhibitors
40388Carbonic Anhydrase Activators. Activation of Isozymes I, II, IV, VA, VII and XIV With L- and D-histidine and Crystallographic Analysis of Their Adducts With Isoform II: Engineering Proton Transfer Processes Within the Active Site of an Enzyme
42160TNE Crystal Structure of the Human Carbonic Anhydrase II in Complex With a Fluorescent Inhibitor
39288Carbonic Anhydrase Activators. Activation of Isoforms I, II, IV, VA, VII and XIV With L- and D- Phenylalanine and Crystallographic Analysis of Their Adducts With Isozyme II: Sterospecific Recognition Within the Active Site of an Enzyme and ITS Consequence
39294Carbonic Anhydrase Activators. Activation of Isoforms I, II, IV, VA, VII and XIV With L- and D- Phenylalanine, Structure With D-phenylalanine
42777Activation of Human Carbonic Anhydrase II by Exogenous Proton Donors
42778Activation of Human Carbonic Anhdyrase II by Exogenous Proton Donors
42779Activation of Human Carbonic Anhydrase II by Exogenous Proton Donors
37789Human Carbonic Anhydrase II Complexed With Two-prong Inhibitors
38299Human Carbonic Anhydrase II Complexed With Two-prong Inhibitors
38300Human Carbonic Anhydrase II Complexed With Two-prong Inhibitors
38301Human Carbonic Anhydrase II Complexed With Two-prong Inhibitors
43823Crystal Structure Analysis of the Human Carbonic Anhydrase II in Complex With a 2-substituted Estradiol Bis-sulfamate
39968N-hydroxyurea, a Versatile Zinc Binding Function in the Design of Metalloenzyme Inhibitors
45001Carbonic Anhydrase Inhibitors: Clashing With Ala65 as a Means of Designing Isozyme-selective Inhibitors That Show LOW Affinity for the Ubiquitous Isozyme II
58026H94n Carbonic Anhydrase II Complexed With Acetazolamide
41623Crystal Structure of the Human Carbonic Anhydrase II in Complex With a Hypoxia-activatable Sulfonamide
46220Carbonic Anhydrase Activators: Solution and X-ray Crystallography for the Interaction of Andrenaline With Various Carbonic Anhydrase Isoforms
46222Crystal Structure Analysis of Human Carbonic Anhydrase II in Complex With a Benzenesulfonamide Derivative
43360Crystal Structure of the Human Carbonic Anhydrase II in Complex With the 5-amino-1,3,4-thiadiazole-2-sulfonamide Inhibitor
42272Crystal Structure of the Human Carbonic Anhydrase II in Complex With the 5-(4-amino-3-chloro-5-fluorophenylsulfonamido)-1,3,4-thiadiazole- 2-sulfonamide Inhibitor
46271Refine Atomic Structure of Human Carbonic Anhydrase II
46355Structure of Inhibitor Binding to Carbonic Anhydrase II
46356Structure of Inhibitor Binding to Carbonic Anhydrase II
46358Structure of Inhibitor Binding to Carbonic Anhydrase II
46359Structure of Inhibitor Binding to Carbonic Anhydrase II
45683Structural and Kinetic Effect of Hydrophobic Mutations in the Active Site of Human Carbonic Anhydrase II
45684Structural and Kinetic Effects of Hydrophobic Mutations in the Active Site of Human Carbonic Anhydrase II
45687Structural and Kinetic Effects of Hydrophobic Mutations on the Active Site of Human Carbonic Anhydrase II
45688Structural and Kinetic Effects of Hydrophobic Mutations on the Active Site of Human Carbonic Anhydrase II
45693Structural Effects of Hydrophobic Mutations on the Active Site of Human Carbonic Anhydrase II
45694Structural and Kinetic Effects of Hydrophobic Mutations in the Active Site of Human Carbonic Anhydrase II
45695Structural and Kinetic Effects of Hydrophobic Mutations in the Active Site of Human Carbonic Anhydrase II
46398Crystal Structure of the Carbonic Anhydrase II Complexed With Hydroxysulfamide Inhibitor
64617Inhibition of Carbonic Anhydrase II by Thioxolone: a Mechanistic and Structural Study
62349Inhibition of Carbonic Anhydrase II by Thioxolone: a Mechanistic and Structural Study
54072The Crystal Structure of the Human Carbonic Anhydrase II in Complex With 4,5-dichloro-benzene-1,3-disulfonamide
54073The Crystal Structure of the Human Carbonic Anhydrase II in Complex With 4-amino-6-chloro-benzene-1,3-disulfonamide
54074The Crystal Structure of the Human Carbonic Anhydrase II in Complex With 4-amino-6-trifluoromethyl-benzene-1,3- Disulfonamide
59363Carbonic Anhydrase II in Complex With Saccharin
59365Carbonic Anhydrase Inhibitors. Interaction of the Antiepileptic Drug Sulthiame With Twelve Mammalian Isoforms: Kinetic and X-ray Crystallographic Studies
59378Carbonic Anhydrase II in Complex With Saccharin at 1.95 Angstrom
61978Crystal Structure of the Complex of Hcaii With an Indane-sulfonamide Inhibitor
61979Crystal Structure of the Complex of Hcaii With an Indane-sulfonamide Inhibitor
64748The Crystal Structure of the Complex of Hcaii With a Bioreductive Antitumor Derivative
75252Human Carbonic Anhydrase in Complex With CO2
75253Human Carbonic Anhydrase II in Complex With Bicarbonate
81053a Chimeric Microtubule Disruptor With Efficacy on a Taxane Resistant Cell Line
80222Highly Potent First Examples of Dual Aromatase-steroid Sulfatase Inhibitors Based on a Biphenyl Template
77934Thermodynamic Optimisation of Carbonic Anhydrase Fragment Inhibitors
77935Thermodynamic Optimisation of Carbonic Anhydrase Fragment Inhibitors
77936Thermodynamic Optimisation of Carbonic Anhydrase Fragment Inhibitors
77937Thermodynamic Optimisation of Carbonic Anhydrase Fragment Inhibitors
81061Structures of Human Carbonic Anhydrase II Inhibitor Complexes Reveal a Second Binding Site for Steroidal and Non-steroidal Inhibitors
81062Structures of Human Carbonic Anhydrase II Inhibitor Complexes Reveal a Second Binding Site for Steroidal and Non-steroidal Inhibitors
81063Structures of Human Carbonic Anhydrase II Inhibitor Complexes Reveal a Second Binding Site for Steroidal and Non-steroidal Inhibitors
62045Carbonic Anhydrase Inhibitors. Interaction of 2- (Hydrazinocarbonyl)-3-phenyl-1h-indole-5-sulfonamide With Twelve Mammalian Isoforms: Kinetic and X-ray Crystallographic Studies
67155Crystal Structure of the Human Carbonic Anhydrase II in Complex With STX 641 at 1.85 Angstroms Resolution
62058Carbonic Anhydrase Inhibitors. Interaction of 2-n,n- Dimethylamino-1,3,4-thiadiazole-5-methanesulfonamide With Twelve Mammalian Isoforms: Kinetic and X-ray Crystallographic Studies
65225Carbonic Anhydrase Inhibitors. Sulfonamide Diuretics Revisited OLD Leads for NEW Applications
68982Crystal Structure of Human Carbonic Anhydrase II in Complex With Stx237
58278Crystallographic Studies of Inhibitor Binding Sites in Human Carbonic Anhydrase II. a Pentacoordinated Binding of the Scn-ion to the Zinc at High PH
63726Crystal Structure of the Human Carbonic Anhydrase II in Complex With Ethoxzolamide
64713Human Carbonic Anhydrase II Complexed With Cryptophane Biosensor and Xenon
69941USE of a Carbonic Anhydrase II, IX Active-site Mimic, for the Purpose of Screening Inhibitors for Possible Anti- Cancer Properties
66472Human Carbonic Anhydrase II Bound With Substrate Carbon Dioxide
66473APO Human Carbonic Anhydrase II Bound With Substrate Carbon Dioxide
69942USE of Carbonic Anhydrase II, IX Active-site Mimic, for the Purpose of Screening Inhibitors for Possible Anti-cancer Properties
69943USE of Carbonic Anhydrase II, IX Active-site Mimic, for the Purpose of Screening Inhibitors for Possible Anti-cancer Properties
69945USE of Carbonic Anhydrase II, IX Active-site Mimic, for the Purpose of Screening Inhibitors for Possible Anti-cancer Properties
69946USE of Carbonic Anhydrase II, IX Active-site Mimic, for the Purpose of Screening Inhibitors for Possible Anti-cancer Properties
69947USE of Carbonic Anhydrase II, IX Active-site Mimic, for the Purpose of Screening Inhibitors for Possible Anti-cancer Properties
69948USE of Carbonic Anhydrase II, IX Active-site Mimic, for the Purpose of Screening Inhibitors for Possible Anti-cancer Properties
69949USE of Carbonic Anhydrase II, IX Active-site Mimic, for the Purpose of Screening Inhibitors for Possible Anti-cancer Properties
69950USE of Carbonic Anhydrase II, IX Active-site Mimic, for the Purpose of Screening Inhibitors for Possible Anti-cancer Properties
69951USE of Carbonic Anhydrase II, IX Active-site Mimic, for the Purpose of Screening Inhibitors for Possible Anti-cancer Properties
66043Carbonic Anhydrase Inhibitors. Interaction of the Antitumor Sulfamate Emd-486019 With Twelve Mammalian Isoforms: Kinetic and X-ray Crystallographic Studies
67905Role of Hydrophilic Residues in Proton Transfer During Catalysis by Human Carbonic Anhydrase II (N62a)
67906X-ray Crystal Structure of Mutant N62v Human Carbonic Anhydrase II
67907X-ray Crystal Structure of Mutant N62t of Human Carbonic Anhydrase II
67908X-ray Crystal Structure of Mutant N62d of Human Carbonic Anhydrase II
74840Carbonic Anhydrase Activators: Kinetic and X-ray Crystallographic Study for the Interaction of D- and L- Tryptophan With the Mammalian Isoforms I-xiv
76557Crystal Structure of the Complex Between Carbonic Anhydrase II and a Spin-labeled Sulfonamide Incorporating Tempo Moiety
70245Carbonic Anhydrase Inhibitors. Comparison of Chlorthalidone and Indapamide X-ray Crystal Structures in Adducts With Isozyme II: When Three Water Molecules Make the Difference
77143Coumarins ARE a Novel Class of Suicide Carbonic Anhydrase Inhibitors
76072X RAY Structure of the Complex Between Carbonic Anhydrase II and LC Inhibitors
75465Apo-human Carbonic Anhydrase II Revisited: Implications of the Loss of a Metal in Protein Structure, Stability and Solvent Network
82172Crystal Structure of TEH Complex Between CA II and the Activ
77322Human Carbonic Anhydrase II in Complex With (2,3,4,6-tetra-o-acetyl- Beta-d-galactopyranosyl) -(1-4)-1,2,3,6-tetra-o-acetyl-1-thio-beta-d- Glucopyranosylsulfonamide
77323Human Carbonic Anhydrase II in Complex With 1-s-d- Galactopyranosylsulfonamide
77324Human Carbonic Anhydrase II in Complex With Alpha-d- Glucopyranosyl-(1->4)-1-thio-beta-d- Glucopyranosylsulfonamide
77325Human Carbonic Anhydrase II in Complex With Topiramate
80430Crystal Structure of Human Carbonic Anhydrase Isozyme II With 3- Methylthiobenzimidazo[1,2-c][1,2,3]thiadiazol-7-sulfonamide
78581Human Carbonic Anhydrase II Complexed With Acetazolamide
76888The Crystal Structure of the Human Carbonic Anhydrase II in Complex With an Aliphatic Sulfamate Inhibitor
76889The Crystal Structure of the Human Carbonic Anhydrase II in Complex With an Aliphatic Bis-sulfamate Inhibitor
76890The Crystal Structure of the Human Carbonic Anhydrase II in Complex With an Aliphatic Bis-sulfamate Inhibitor
76892The Crystal Structure of the Human Carbonic Anhydrase II in Complex With an Aliphatic Sulfamate Inhibitor
79606The Coumarin-binding Site in Carbonic Anhydrase: the Antiepileptic Lacosamide as an Example
80656Structure of Inhibitor Binding to Carbonic Anhydrase II
78215Nitric Oxide-donating Carbonic Anhydrase Inhibitors for the Treatment of Open-angle Glaucoma
81978Human Carbonic Anhydrase II With a Sulfonamide Inhibitor
79621Crystal Structure of the Complex Between Carbonic Anhydrase II and Anions
86218Mutant Carbonic Anhydrase II in Complex With an Azide and an Alkyne
79328Neutron Structure of Human Carbonic Anhydrase II
90592Carbonic Anhydrase II H64c Mutant in Complex With an in Situ Formed Triazole
84364Crystal Structure of Cobalt (Iii) Human Carbonic Anhydrase II at PH 6.0
84365Crystal Structure of Cobalt (Ii) Human Carbonic Anhydrase II at PH 8.5
84366Crystal Structure of Cobalt (Ii) Human Carbonic Anhydrase II at PH 11.0
79643High Resolution Structure of Human Carbonic Anhydrase II at 0.9 a
83314Polyamines Inhibit Carbonic Anhydrases
87681Human Carbonic Anhydrase II Complexed With Althiazide
90736Carbonic Anhydrase II in Complex With Novel Sulfonamide Inhibitor
90737Carbonic Anhydrase II in Complex With Novel Sulfonamide Inhibitor
88035The Crystal Structure of a Nami A-carbonic Anhydrase II Adduct Discloses the Mode of Action of This Novel Anticancer Metallodrug
86238Carbonic Anhydrase in Complex With Fragment
90738Carbonic Anhydrase II Mutant W5c-h64c With Opened Disulfide Bond
90739Carbonic Anhyrdase II Mutant W5ch64c With Closed Disulfide Bond in Complex With Sulfate
88662Crystal Structure of Human Carbonic Anhydrase Isozyme II With 4-{2-[n- (6-chloro-5-nitropyrimidin-4-yl)amino]ethyl}benzenesulfonamide
90740Carbonic Anhydrase II in Complex With Novel Sulfonamide Inhibitor
90741Carbonic Anhydrase II in Complex With Novel Sulfonamide Inhibitor
85590Crystal Structure of Human Carbonic Anhydrase Isozyme II With 4-{2-[n- (6-methoxy-5-nitropyrimidin-4-yl)amino]ethyl}benzenesulfonamide
85591Crystal Structure of Human Carbonic Anhydrase Isozyme II With 4-[n-(6- Chloro-5-nitropyrimidin-4-yl)amino]benzenesulfonamide
85592Crystal Structure of Human Carbonic Anhydrase Isozyme II With 4-{[n- (6-chloro-5-formyl-2-methylthiopyrimidin-4-yl) Amino]methyl}benzenesulfonamide
90742Carbonic Anhydrase II Mutant H64c in Complex With Carbonate
90743Fragment Tethered to Carbonic Anhydrase II H64c Mutant
85906Crystal Structure of Human Carbonic Anhydrase Isozyme II With 2- Chloro-5-[(6,7-dihydro-1h-[1,4]dioxino[2,3-f]benzimidazol-2- Ylsulfanyl)acetyl]benzenesulfonamide
88344Crystal Structure of Human Carbonic Anhydrase Isozyme II With 5-{[(5- Bromo-1h-benzimidazol-2-yl)sulfanyl]acetyl}-2- Chlorobenzenesulfonamide
88937Crystal Structure of Human Carbonic Anhydrase Isozyme II With 5-(1h- Benzimidazol-1-ylacetyl)-2-chlorobenzenesulfonamide
83504Crystal Structure of Human Cabonic Anhydrase II in Adduct With an Adamantyl Analogue of Acetazolamide in a Novel Hydrophobic Binding Pocket
85593Crystal Structure of Human Carbonic Anhydrase Isozyme II With 4-{[(5- Nitro-6-oxo-1,6-dihydro-4-pyrimidinyl)amino]methyl}benzenesulfonamide
85594Crystal Structure of Human Carbonic Anhydrase Isozyme II With 4-{[n- (6-methoxy-5-nitropyrimidin-4-yl)amino]methyl}benzenesulfonamide
85595Crystal Structure of Human Carbonic Anhydrase Isozyme II With 4-{[n- (6-benzylamino-5-nitropyrimidin-4-yl)amino]methyl}benzenesulfonamide
85596Crystal Structure of Human Carbonic Anhydrase Isozyme II With 4-[n-(6- Chloro-5-formyl-2-methylthiopyrimidin-4-yl)amino]benzenesulfonamide
89983Human Carbonic Anhydsase II in Complex With an Aryl Sulfonamide Inhibitor
89984Crystal Structure of Human Carbonic Anhydrase II in Complex With a 1, 3,5-triazine-substituted Benzenesulfonamide Inhibitor
89985The Crystal Structure of Human Carbonic Anhydrase II in Complex With a 1,3,5-triazine-substituted Benzenesulfonamide Inhibitor
83353Human Carbonic Anhydrase II Mutant K170a
83354Human Carbonic Anhydrase II Mutant K170d
83355Human Carbonic Anhydrase II Mutant K170e
83356Human Carbonic Anhydrase II Mutant K170h
82836Carbonic Anhydrase Inhibitors: Crystallographic and Solution Studies for the Interaction of a Boron Containing Aromatic With Mammalian Isoforms I-xv
82667Human Carbonic Anhydrase II in a Doubled Monoclinic Cell: a RE- Determination
88346Crystal Structure of Human Carbonic Anhydrase Isozyme II With 2- Chloro-5-[(1h-imidazo[4,5-c]quinolin-2-ylsulfanyl) Acetyl]benzenesulfonamide
89060Human Carbonic Ahydrase II in Complex With a Benzenesulfonamide Inhibitor
89209Crystal Structure of Human Carbonic Anhydrase II in Complex With a Benzenesulfonamide Inhibitor
89061Crystal Structure of Human Carbonic Anhydrase II in Complex With a Benzenesulfonamide Inhibitor
89062Crystal Structure of Human Carbonic Anhydrase II in Complex With a Benzenesulfonamide Inhibitor
89063Crystal Structure of Human Carbonic Anhydrase II in Complex With a Benzenesulfonamide Inhibitor
89990Human Carbonic Anhydrase II in Complex With 2-(3-chloro-4- Hydroxyphenyl)-n-(4-sulfamoylphenethyl)acetamide
90002Human Carbonic Anhydrase II in Complex With (+)-xylariamide a
89717Crystal Structure of Human Carbonic Anhydrase II With 6,7-dimethoxy-1- Methyl-3,4-dihydroisoquinoline-2(1h)-sulfonamide
90843Human Caii Bound to N-(4-sulfamoylphenyl)-2-(thiophen-2-yl) Acetamide
90844Hcarbonic Anhydrase II Bound to N-(2-fluoro.4-sulfamoylphenyl)-2- (Thiophen-2-yl) Acetamide
58400Engineering the Hydrophobic Pocket of Carbonic Anhydrase II
54707Refined Structure of Human Carbonic Anhydrase II at 2.0 Angstroms Resolution
58477Conformational Mobility of His-64 in the Thr-200 (Right Arrow) SER Mutant of Human Carbonic Anhydrase II
54759Refined Structure of Human Carbonic Anhydrase II at 2.0 Angstroms Resolution
58532Engineering the Hydrophobic Pocket of Carbonic Anhydrase II
58569Engineering the Hydrophobic Pocket of Carbonic Anhydrase II
58600Engineering the Hydrophobic Pocket of Carbonic Anhydrase II
58618Engineering the Hydrophobic Pocket of Carbonic Anhydrase II