3FZK: Crystal Structures of Hsc70/Bag1 in Complex with Small Molecule Inhibitors

PDB ID: 3FZKDownload
MMDB ID: 70256
PDB Deposition Date: 2009/1/26
Updated in MMDB: 2023/11
Experimental Method:
x-ray diffraction
Resolution: 2.1  Å
Source Organism:
Similar Structures:
Biological Unit for 3FZK: dimeric; determined by author and by software (PISA)
Molecular Components in 3FZK
Label Count Molecule
Proteins (2 molecules)
1
Heat Shock Cognate 71 KDA Protein
(Gene symbol: HSPA8)
Molecule annotation
1
BAG Family Molecular Chaperone Regulator 1
(Gene symbol: BAG1)
Molecule annotation
Chemicals and Non-standard biopolymers (3 molecules)
1
1
2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL
2
1
CHLORIDE IONCHLORIDE ION
3
1
(2R,3R,4S,5R)-2-[6-amino-8-[(3,4-dichlorophenyl)methylamino]purin-9-yl]-5-(hydroxymethyl)oxolane-3,4-diol(2R,3R,4S,5R)-2-[6-amino-8-[(3,4-dichlorophenyl)methylamino]purin-9-yl]-5-(hydroxymethyl)oxolane-3,4-diol
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303