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MMDB Description
7878Hiv-1 Protease Complexed With a Tripeptide Inhibitor
73437Hiv-1 Protease in Complex With Sdz283-910
73438Crystallographic Analysis of Human Immunodeficiency Virus 1 Protease With an Analog of the Conserved Ca-p2 Substrate: Interactions With Frequently Occurring Glutamic Acid Residue at P2' Position of Substrates
73440Structural Basis for Specificity of Retroviral Proteases
8033G48h Mutant of Hiv-1 Protease in Complex With a Peptidic Inhibitor U-89360e
158Hydroxyethylene Isostere Inhibitors of Human Immunodeficiency Virus-1 Protease: Structure-activity Analysis Using Enzyme Kinetics, X-ray Crystallography, and Infected T-cell Assays
6725Structure of a Non-peptide Inhibitor Complexed With Hiv-1 Protease: Developing a Cycle of Structure-based Drug Design
6331Hiv-1 Protease in Complex With the Cyclic Sulfamide Inhibitor Aha006
6457Hiv-1 Protease in Complex With the Cyclic Urea Inhibitor Aha001
7498Active-site Mobility in Human Immunodeficiency Virus Type 1 Protease as Demonstrated by Crystal Structure of A28s Mutant
12486Hiv-1 Protease Complexed With Macrocyclic Peptidomimetic Inhibitor 1
8354Hiv-1 (2:31-37) Protease Complexed With Inhibitor Sb203386
8355Hiv-1 (2:31-37, 47, 82) Protease Complexed With Inhibitor Sb203386
8848Hiv-1 (2: 31, 33-37) Protease Complexed With Inhibitor Sb203386
12513Counteracting Hiv-1 Protease Drug Resistance: Structural Analysis of Mutant Proteases Complexed With Xv638 and Sd146, Cyclic Urea Amides With Broad Specificities
12526Hiv-1 Protease (I84v) Complexed With Xv638 of Dupont Pharmaceuticals
4873Hiv-1 Protease-dmp323 Complex in Solution, NMR, 28 Structures
4872Hiv-1 Protease-dmp323 Complex in Solution, NMR Minimized Average Structure
12528Hiv-1 Protease (V82fi84v) Double Mutant Complexed With Xv638 of Dupont Pharmaceuticals
12529Hiv-1 Protease (V82fi84v) Double Mutant Complexed With Sd146 of Dupont Pharmaceuticals
14951Alternate Binding Site for the P1-p3 Group of a Class of Potent Hiv-1 Protease Inhibitors as a Result of Concerted Structural Change in 80's Loop
14952Alternate Binding Site for the P1-p3 Group of a Class of Potent Hiv-1 Protease Inhibitors as a Result of Concerted Structural Change in 80's Loop
14953Alternate Binding Site for the P1-p3 Group of a Class of Potent Hiv-1 Protease Inhibitors as a Result of Concerted Structural Change in 80's Loop
14954Alternate Binding Site for the P1-p3 Group of a Class of Potent Hiv-1 Protease Inhibitors as a Result of Concerted Structural Change in 80's Loop
75373Regioselective Structural and Functional Mimicry of Peptides. Design of Hydrolytically Stable Cyclic Peptidomimetic Inhibitors of Hiv-1 Protease
19717Hiv-1 Protease in Complex With the Inhibitor Bea435
19718Hiv-1 Protease in Complex With the Inhibitor Bea425
19719Hiv-1 Protease in Complex With the Inhibitor Msl370
11409Hiv-1 Protease V82fi84v Double Mutanttipranavir Complex
11395Hiv-1 Protease Triple Mutanttipranavir Complex
73540Structural and Kinetic Analysis of Drug Resistant Mutants of Hiv-1 Protease
4447Hiv-1 Protease in Complex With a Difluoroketone Containing Inhibitor A79285
6563Structure of Hiv-1 Protease Complex
73558Structural and Kinetic Analysis of Drug Resistant Mutants of Hiv-1 Protease
73567Structural and Kinetic Analysis of Drug Resistant Mutants of Hiv-1 Protease
19722Hiv-1 Protease in Complex With the Inhibitor Bea322
19723Hiv-1 Protease in Complex With the Inhibitor Bea369
19724Hiv-1 Protease in Complex With the Inhibitor Bea388
19725Hiv-1 Protease in Complex With the Inhibitor Bea403
19726Hiv-1 Protease in Complex With the Inhibitor Bea409
19727Hiv-1 Protease in Complex With the Inhibitor Bea428
19728Hiv-1 Protease in Complex With the Inhibitor Msa367
16605HOW Does a Symmetric Dimer Recognize an Asymmetric Substrate? a Substrate Complex of Hiv-1 Protease
15090Crystal Structure of an in Vivo Hiv-1 Protease Mutant in Complex With Saquinavir: Insights Into the Mechanisms of Drug Resistance
73595Structural Implications of Drug Resistant Mutants of Hiv-1 Protease: High Resolution Crystal Structures of the Mutant Proteasesubstrate Analog Complexes
73596Structural Implications of Drug Resistant Mutants of Hiv-1 Protease: High Resolution Crystal Structures of the Mutant Proteasesubstrate Analog Complexes
73597Structural Implications of Drug Resistant Mutants of Hiv-1 Protease : High Resolution Crystal Structures of the Mutant Proteasesubstrate Analog Complexes
73598Structural Implications of Drug Resistant Mutants of Hiv-1 Protease: High Resolution Crystal Structures of the Mutant Proteasesubstrate Analog Complexes
73599Structural Implications of Drug Resistant Mutants of Hiv-1 Protease: High Resolution Crystal Structures of the Mutant Proteasesubstrate Analog Complexes
73600Structural Implications of Drug Resistant Mutants of Hiv-1 Protease: High Resolution Crystal Structures of the Mutant Proteasesubstrate Analog Complexes
73601Structural Implications of Drug Resistant Mutants of Hiv-1 Protease: High Resolution Crystal Structures of the Mutant Proteasesubstrate Analog Complexes
73608Crystal Structure of the Complex of Hiv-1 Protease With a Peptidomimetic Inhibitor
16449Hiv-1 Protease With Cyclic Sulfamide Inhibitor, Aha047
16387Crystal Structure of Hiv-1 Protease in Complex With Inhibitor, Aha024
5732Hiv-1 Protease Mutant With VAL 82 Replaced by ASP (V82d) Complexed With U89360e (Inhibitor)
5733Hiv-1 Protease Mutant With VAL 82 Replaced by ASN (V82n) Complexed With U89360e (Inhibitor)
5734Hiv-1 Protease (Wild Type) Complexed With U89360e (Inhibitor)
3498a Check on Rational Drug Design. Crystal Structure of a Complex of Hiv-1 Protease With a Novel Gamma-turn Mimetic
76639The Crystal Structures at 2.2 Angstroms Resolution of Hydroxyethylene-based Inhibitors Bound to Human Immunodeficiency Virus Type 1 Protease Show That the Inhibitors ARE Present in Two Distinct Orientations
73641The Crystal Structures at 2.2 Angstroms Resolution of Hydroxyethylene-based Inhibitors Bound to Human Immunodeficiency Virus Type 1 Protease Show That the Inhibitors ARE Present in Two Distinct Orientations
56338The Three-dimensional Structure of the Aspartyl Protease From the Hiv-1 Isolate BRU
3495Comparative Analysis of the X-ray Structures of Hiv-1 and Hiv-2 Proteases in Complex With CGP 53820, a Novel Pseudosymmetric Inhibitor
73646Crystal Structure of a Complex of Hiv-1 Protease With a Dihydroethylene-containing Inhibitor: Comparisons With Molecular Modeling
1233Inhibition of Human Immunodeficiency Virus-1 Protease by a C2- Symmetric Phosphinate Synthesis and Crystallographic Analysis
5809Hiv-1 Protease Triple Mutantu103265 Complex
1237Rational Design, Synthesis and Crystallographic Analysis of a Hydroxyethylene-based Hiv-1 Protease Inhibitor Containing a Heterocyclic P1'-p2' Amide Bond Isostere
1239Crystal Structure of Hiv-1 Protease in Complex With Vx-478, a Potent and Orally Bioavailable Inhibitor of the Enzyme
4428Hiv-1 Protease Complexed With the Inhibitor Kni-272
4292Crystal Structure at 1.9 Angstroms Resolution of Human Immunodeficiency Virus (Hiv) II Protease Complexed With L- 735,524, an Orally Bioavailable Inhibitor of the HIV Proteases
1260X-ray Crystallographic Studies of a Series of Penicillin- Derived Asymmetric Inhibitors of Hiv-1 Protease
1261X-ray Crystallographic Studies of a Series of Penicillin- Derived Asymmetric Inhibitors of Hiv-1 Protease
1262X-ray Crystallographic Studies of a Series of Penicillin- Derived Asymmetric Inhibitors of Hiv-1 Protease
8945Nonpeptide Cyclic Cyanoguanidines as HIV Protease Inhibitors
1281Influence of Stereochemistry on Activity and Binding Modes for C2 Symmetry-based Diol Inhibitors of Hiv-1 Protease
1282Influence of Stereochemistry on Activity and Binding Modes for C2 Symmetry-based Diol Inhibitors of Hiv-1 Protease
1283Influence of Stereochemistry on Activity and Binding Modes for C2 Symmetry-based Diol Inhibitors of Hiv-1 Protease
1284Influence of Stereochemistry on Activity and Binding Modes for C2 Symmetry-based Diol Inhibitors of Hiv-1 Protease
72319Rational Design of Potent, Bioavailable, Nonpeptide Cyclic Ureas as HIV Protease Inhibitors
1289Structural Basis of Drug Resistance for the V82a Mutant of Hiv-1 Protease: Backbone Flexibility and Subsite Repacking
9831Molecular Recognition of Cyclic Urea HIV Protease Inhibitors
49549Hiv-1 Proteinase Complexed With RO 31-8959
7007Hiv-1 Protease Dimer Complexed With A-84538
49668Crystal Structure of Hiv-1 Protease Complexed With a Hydroxyethylamine Peptidomimetic Inhibitor
21361Inhibitor of HIV Protease With Unusual Binding Mode Potently Inhibiting Multi-resistant Protease Mutants
21362Inhibitor of HIV Protease With Unusual Binding Mode Potently Inhibiting Multi-resistant Protease Mutants
20134Combining Mutations in Hiv-1 Protease to Understand Mechanisms of Resistance
20135Combining Mutations in Hiv-1 Protease to Understand Mechanisms of Resistance
73738Combining Mutations in Hiv-1 Protease to Understand Mechanisms of Resistance
73739Combining Mutations in Hiv-1 Protease to Understand Mechanisms of Resistance
18417Lack of Synergy for Inhibitors Targeting a Multi-drug Resistant Hiv-1 Protease
18418Lack of Synergy for Inhibitors Targeting a Multi-drug Resistant Hiv-1 Protease
18419Lack of Synergy for Inhibitors Targeting a Multi-drug Resistant Hiv-1 Protease
18420Lack of Synergy for Inhibitors Targeting a Multi-drug Resistant Hiv-1 Protease
71085Substrate Shape Determines Specificity of Recognition Recognition for Hiv-1 Protease: Analysis of Crystal Structures of Six Substrate Complexes
71088Substrate Shape Determines Specificity of Recognition Recognition for Hiv-1 Protease: Analysis of Crystal Structures of Six Substrate Complexes
71091Substrate Shape Determines Specificity of Recognition Recognition for Hiv-1 Protease: Analysis of Crystal Structures of Six Substrate Complexes
71092Substrate Shape Determines Specificity of Recognition Recognition for Hiv-1 Protease: Analysis of Crystal Structures of Six Substrate Complexes
71093Substrate Shape Determines Specificity of Recognition Recognition for Hiv-1 Protease: Analysis of Crystal Structures of Six Substrate Complexes
50030Je-2147-hiv Protease Complex
50197Crystal Structure of the Complex of Mutant Hiv-1 Protease (A71v, V82t, I84v) With an Ethylenamine Peptidomimetic Inhibitor Boc-phe-psi[ch2ch2nh]-phe-glu-phe-nh2
50201Hiv-1 Protease in Complex With an Ethyleneamine Inhibitor
7493Hiv-1 Mutant (I84v) Protease Complexed With Dmp450
7494Hiv-1 Mutant (I84v) Protease Complexed With Dmp323
7495Hiv-1 Mutant (V82f) Protease Complexed With Dmp323
7496Hiv-1 Mutant (V82f, I84v) Protease Complexed With Dmp323
24931Structure of HIV Protease (Mutant Q7K L33i L63i) Complexed With Kni- 577
24932Structure of HIV Protease (Mutant Q7K L33i L63i V82f I84v ) Complexed With Kni-577
24933The HIV Protease (Mutant Q7K L33i L63i) Complexed With Kni-764 (AN Inhibitor)
24934The HIV Protease (Mutant Q7K L33i L63i V82f I84v) Complexed With Kni- 764 (AN Inhibitor)
21781Viability of a Drug-resistant Hiv-1 Protease Mutant: Structural Insights for Better Antiviral Therapy
21782Viability of a Drug-resistant Hiv-1 Protease Mutant: Structural Insights for Better Antiviral Therapy
21783Viability of a Drug-resistant Hiv-1 Protease Mutant: Structural Insights for Better Antiviral Therapy
21784Viability of a Drug-resistant Hiv-1 Protease Mutant: Structural Insights for Better Antiviral Therapy
21013Crystal Structure of Hiv-1 Protease Complexed With Lopinavir
21824Viability of a Drug-resistant Hiv-1 Protease Variant: Structural Insights for Better Anti-viral Therapy
504621.03 a Structure of Hiv-1 Protease: Inhibitor Binding Inside and Outside the Active Site
26006Crystal Structure of Hiv-1 Protease-hup
21903Crystal Structure of Hiv-1 Protease Complexed With Ldc271
21904Crystal Structure of HIV Protease Complexed With Lgz479
50612Native Hiv-1 Proteinase
50613Hiv-1 Proteinase Mutant A71t, V82a
50614Hiv-1 Protease Complexed With an Inhibitor Lp-130
9068Viracept (R) (Nelfinavir Mesylate, Ag1343): a Potent Orally Bioavailable Inhibitor of Hiv-1 Protease
4836Hiv-1 Protease Dimer Complexed With A-98881
26485Solution Structure of the Mature Hiv-1 Protease Monomer
6661Hiv-1 Protease Inhibitors Wiih LOW Nanomolar Potency
6662Hiv-1 Protease Inhibitors Wiih LOW Nanomolar Potency
6663Hiv-1 Protease Inhibitors Wiih LOW Nanomolar Potency
6664Hiv-1 Protease Inhibitors Wiih LOW Nanomolar Potency
32717Crystal Structure of the Complex of Resistant Strain of Hiv- 1 Protease(v82a Mutant) With Ritonavir
30822Crystal Structures of a Multidrug-resistant Hiv-1 Protease Reveal an Expanded Active Site Cavity
30824Crystal Structures of a Multidrug-resistant Hiv-1 Protease Reveal an Expanded Active Site Cavity
30832Crystal Structures of a Multidrug-resistant Hiv-1 Protease Reveal an Expanded Active Site Cavity
2155An Orally-bioavailable Hiv-1 Protease Inhibitor Containing an Imidazole-derived Peptide Bond Replacement. Crystallographic and Pharmacokinetic Analysis
27816Crystal Structures of HIV Protease V82a and L90m Mutants Reveal Changes in Indinavir Binding Site
27817Crystal Structures of HIV Protease V82a and L90m Mutants Reveal Changes in Indinavir Binding Site
27818Crystal Structures of HIV Protease V82a and L90m Mutants Reveal Changes in Indinavir Binding Site
29356Comparing the Accumulation of Active Site and Non-active Site Mutations in the Hiv-1 Protease
29357Comparing the Accumulation of Active Site and Non-active Site Mutations in the Hiv-1 Protease
34058Crystal Structure of Hiv-1 Protease Complexed With a Product of Autoproteolysis
32736HIV Protease Wild-type in Complex With Tmc114 Inhibitor
33412The Structural and Thermodynamic Basis for the Binding of Tmc114, a Next-generation Hiv-1 Protease Inhibitor
33413Crystal Structure of Inhibitor Amprenavir in Complex With a Multi-drug Resistant Variant of Hiv-1 Protease (L63pv82ti84v)
29418Crystal Structure of HIV Protease Complexed With Arylsulfonamide Azacyclic Urea
5483HIV Triple Mutant Protease Complexed With Inhibitor Sb203386
32250Crystal Structure of Ap2v Substrate Variant of Nc-p1 Decamer Peptide in Complex With V82ad25n Hiv-1 Protease Mutant
32251Crystal Structure of Decamer Ncp1 Substrate Peptide in Complex With Wild-type D25n Hiv-1 Protease Variant
34066Wide Open 1.3a Structure of a Multi-drug Resistant Hiv-1 Protease Represents a Novel Drug Target
74346Crystal Structure of a Hiv-1 Protease in Complex With Peptidomimetic Inhibitor Ki2-phe-glu-glu-nh2
57578Hiv-1 Protease Complex With U095438 [3-[1-(4-bromophenyl) Isobutyl]-4- Hydroxycoumarin
9368Hiv-1 Protease Complexed With the Inhibitor Hoebay 793 Hexagonal Form
9073Hiv-1 Protease Complexed With the Inhibitor Hoebay 793 Orthorhombic Form
31015Hiv-1 Protease in Complex With Fluoro Substituted Diol- Based C2-symmetric Inhibitor
31016Hiv-1 Protease in Complex With Fluoro Substituted Diol- Based C2-symmetric Inhibitor
34484Hiv-1 Protease in Complex With Fluoro Substituted Diol- Based C2-symmetric Inhibitor
30102Hiv-1 Protease in Complex With Fluoro Substituted Diol- Based C2-symmetric Inhibitor
30471Hiv-1 Protease in Complex With Asymmetric Inhibitor, Bea568
30472Hiv-1 Protease in Complex With Symmetric Inhibitor, Bea450
33692Hiv-1 Protease in Complex With Pyrrolidinmethanamine
33693Hiv-1 Protease in Complex With Amidhyroxysulfone
32957HIV Protease With Oximinoarylsulfonamide Bound
74459SIV Protease Crystallized With Peptide Product
74460SIV Protease Crystallized With Peptide Product
52200Crystal Structure of the Complex of Mutant Hiv-1 Protease (L63p, A71v, V82t, I84v) With a Hydroxyethylamine Peptidomimetic Inhibitor Boc-phe-psi[r-ch(oh)ch2nh]-phe- Glu-phe-nh2
52209Crystal Structure of a Complex of Mutant Hiv-1 Protease (A71v, V82t, I84v) With a Hydroxyethylamine Peptidomimetic Inhibitor Boc-phe-psi[r-ch(oh)ch2nh]-phe-glu-phe-nh2
74482Crystal Structure of a Complex of Mutant Hiv-1 Protease (A71v, V82t, I84v) With a Hydroxyethylamine Peptidomimetic Inhibitor Boc-phe-psi[s-ch(oh)ch2nh]-phe-glu-phe-nh2
74485Crystal Structure of a Complex of Mutant Hiv-1 Protease (A71v, V82t, I84v) With a Hydroxyethylamine Peptidomimetic Inhibitor
33905HIV Protease With Inhibitor Ab-2
33190HIV Protease With Scripps Ab-3 Inhibitor
52289Crystal Structure of the Complex of Mutant Hiv-1 Protease (A71v, V82t, I84v) With a Hydroxyethylamine Peptidomimetic Inhibitor Boc-phe-psi[r-ch(oh)ch2nh]-phe-glu-phe-nh2
74491Crystal Structure of Complex of a Hydroxyethylamine Inhibitor With Hiv-1 Protease at 2.0a Resolution
74492Crystal Structure of Wild Type Hiv-1 Protease (Bru Isolate) With a Hydroxyethylamine Peptidomimetic Inhibitor Boc-phe- Psi[s-ch(oh)ch2nh]-phe-glu-phe-nh2
35560Crystal Structure of HIV Protease- Metallacarborane Complex
37496High Resolution Structure of Hiv-1 PR With Ts-126
35165Synthesis and Activity of N-axyl Azacyclic Urea Hiv-1 Protease Inhibitors With High Potency Against Multiple Drug Resistant Viral Strains
6680Structure of a Non-peptide Inhibitor Complexed With Hiv-1 Protease: Developing a Cycle of Structure-based Drug Design
52495Crystal Structure Analysis of Hiv-1 Protease Mutant I84v With a Substrate Analog P2-nc
52496Crystal Structure Analysis of Hiv-1 Protease With a Substrate Analog P2-nc
37072Crystal Structure Analysis of Hiv-1 Protease Mutant V82a With a Substrate Analog Ca-p2
86753Crystal Structure Analysis of Hiv-1 Protease Mutant V82a With a Substrate Analog P1-p6
86754Crystal Structure Analysis of Hiv-1 Protease Mutant V82a With a Substrate Analog P2-nc
37075Crystal Structure Analysis of Hiv-1 Protease Mutant V82a With a Substrate Analog P6-pr
86755Crystal Structure Analysis of Hiv-1 Protease With a Substrate Analog P1-p6
86756Crystal Structure Analysis of Hiv-1 Protease With a Substrate Analog P6-pr
40657Structure of Hiv-1 Protease Bound to Atazanavir
86768Kinetics, Stability, and Structural Changes in High Resolution Crystal Structures of Hiv-1 Protease With Drug Resistant Mutations L24i, I50v, and G73s
37090Kinetics, Stability, and Structural Changes in High Resolution Crystal Structures of Hiv-1 Protease With Drug Resistant Mutations L24i, I50v, and G73s
86769Kinetics, Stability, and Structural Changes in High Resolution Crystal Structures of Hiv-1 Protease With Drug Resistant Mutations L24i, I50v, and G73s
37092Kinetics, Stability, and Structural Changes in High Resolution Crystal Structures of Hiv-1 Protease With Drug Resistant Mutations L24i, I50v, and G73s
37094Kinetics, Stability, and Structural Changes in High Resolution Crystal Structures of Hiv-1 Protease With Drug Resistant Mutations L24i, I50v, and G73s
52537Hiv-1 Protease Nl4-3 in Complex With Inhibitor, Tl-3
52538Hiv-1 Protease Nl4-3 1X Mutant
52539Hiv-1 Protease Nl4-3 3X Mutant in Complex With Inhibitor, Tl-3
52540Hiv-1 Protease Nl4-3 6X Mutant
42560Structure of Hiv-1 Protease Mutant Bound to Ritonavir
42561Structure of Hiv-1 Protease Mutant Bound to Indinavir
36187Structure of Hiv1 Protease and Akc4p_133a Complex
36188Structure of Hiv1 Protease and Hh1_173_3a Complex
9577Hiv-1 Protease-inhibitor Complex
9578Hiv-1 Protease-inhibitor Complex
9579Hiv-1 Protease-inhibitor Complex
9580Hiv-1 Protease-inhibitor Complex
9581Hiv-1 Protease-inhibitor Complex
36732Hiv-1 Protease in Complex With Inhibitor Aha455
44310P1' Extended Hiv-1 Protease Inhibitors Encompassing a Tertiary Alcohol in the Transition-state Mimicking Scaffold
44311P1' Extended Hiv-1 Protease Inhibitors Encompassing a Tertiary Alcohol in the Transition-state Mimicking Scaffold
44312P1' Extended Hiv-1 Protease Inhibitors Encompassing a Tertiary Alcohol in the Transition-state Mimicking Scaffold
42731Substrate Envelope and Drug Resistance: Crystal Structure of R01 in Complex With Wild-type Hiv-1 Protease
38234Hiv-1 Protease Mutant D30n Complexed With Inhibitor Tmc114
38235Hiv-1 Protease Mutant L90m Complexed With Inhibitor Tmc114
38237Hiv-1 Protease Mutant I50v Complexed With Inhibitor Tmc114
37729Crystal Structure of HIV Protease D545701 Bound With Gw0385
37730Wild Type HIV Protease Bound With Gw0385
42762X-ray Crystal Structure of Hiv-1 Protease T80s Variant in Complex With the Inhibitor Saquinavir Used to Explore the Role of Invariant Thr80 in Hiv-1 Protease Structure, Function, and Viral Infectivity
42763X-ray Crystal Structure of Hiv-1 Protease T80n Variant in Complex With the Inhibitor Saquinavir Used to Explore the Role of Invariant Thr80 in Hiv-1 Protease Structure, Function, and Viral Infectivity
43759Structural Analysis of Asymmetric Inhibitor Bound to the Hiv-1 Protease V82a Mutant
40850Crystal Structure of Wild-type Inactive (D25n) Hiv-1 Protease Complexed With Wild-type Hiv-1 Nc-p1 Substrate
40851Crystal Structure of a Drug-resistant (V82a) Inactive (D25n) Hiv-1 Protease Complexed With Ap2v Variant of Hiv-1 Nc-p1 Substrate
39342Structure of Unliganded Hiv-1 Protease F53l Mutant
47124Structure of HIV Protease 6X Mutant in APO Form
41020Wild-type Hiv-1 Protease in Complex With Potent Inhibitor Grl06579
47125Structure of HIV Protease Nl4-3 in an Unliganded State
47126Structure of HIV Protease 6X Mutant in Complex With Ab-2
41692Ultra-high Resolution X-ray Crystal Structure of Hiv-1 Protease V32i Mutant With Tmc114 (Darunavir) Inhibitor
58047Three-dimensional Structure of Aspartyl Protease From Human Immunodeficiency Virus Hiv-1
43375Crystal Structure of Kb-19 Complexed With Wild Type Hiv-1 Protease
43376Crystal Structure of Ad-81 Complexed With Wild Type Hiv-1 Protease
60050Crystal Structure of WT Hiv-1 Protease With Gs-8373
58951Hiv-1 Protease With Tmc-126
58952Hiv-1 Protease I84v, L90m With Tmc126
58953Hiv-1 Protease WT With Gs-8374
58954Hiv-1 Protease I84v, L90m With Gs-8374
41799Crystal Structure Analysis of Hiv-1 Protease Mutant V82a With a Potent Non-peptide Inhibitor (Uic-94017)
41803Crystal Structure Analysis of Hiv-1 Protease With a Potent Non-peptide Inhibitor (Uic-94017)
41804Crystal Structure Analysis of Hiv-1 Protease Mutant I84v With a Potent Non-peptide Inhibitor (Uic-94017)
45139Crystal Structure Analysis of Hiv-1 Protease Mutant V82a With a Inhibitor Saquinavir
45140Crystal Structure Analysis of Hiv-1 Protease Mutant V82a With a Inhibitor Saquinavir
45143Crystal Structure Analysis of Hiv-1 Protease Mutant I84v With a Inhibitor Saquinavir
45144Crystal Structure Analysis of Hiv-1 Protease Mutant I84v With a Inhibitor Saquinavir
43491Crystal Structure of Hiv1 Protease in Situ Product Complex
59157Structure of Hiv-1 Protease D25n Complexed With Rt-rh Analogue Peptide Gly-ala-asp-ile-phetyr-leu-asp-gly-ala
59158Structure of Hiv-1 Protease D25n Complexed With the Rt-rh Analogue Peptide Gly-ala-glu-val-phetyr-val-asp-gly-ala
59159Structure of Hiv-1 Protease D25n Complexed With the Rt-rh Analogue Peptide Gly-ala-gln-thr-phetyr-val-asp-gly-ala
43605Crystal Structure of Hiv-1 Protease (Q7k) in Complex With Atazanavir
43606Crystal Structure of Hiv-1 Protease (Q7k, I50v) in Complex With Tipranavir
43607Crystal Structure of Hiv-1 Protease (Trm Mutant) in Complex With Tipranavir
43608Crystal Structure of Hiv-1 Protease (Q7k) in Complex With Tipranavir
43609Crystal Structure of Hiv-1 Protease (Q7k) in Complex With Lopinavir
45722Crystal Structure of the Multi-drug Resistant Mutant Subtype B HIV Protease Complexed With Tl-3 Inhibitor
45723Crystal Structure of the Subtype B Wild Type HIV Protease Complexed With Tl-3 Inhibitor
47218APO Wild-type HIV Protease in the Open Conformation
46591Crystal Structure of Hiv-1 Protease (Q7k, L33i, L63i ) in Complex With Kni-10075
46592Crystal Structure of Hiv-1 Protease (Q7k, L33i, L63i) in Complex With Kni-10033
63765Hiv-1 Protease in Complex With a Pyrrolidine-based Inhibitor
46678Crystal Structure of Wild Type Hiv-1 Protease in Complex With Carb- Ad37
46679Crystal Structure of Wild Type Hiv-1 Protease in Complex With Carb-kb45
63769Hiv-1 Protease in Complex With a Amino Decorated Pyrrolidine-based Inhibitor
63770Hiv-1 Protease in Complex With a Carbamoyl Decorated Pyrrolidine-based Inhibitor
62668Hiv-1 PR Mutant in Complex With Nelfinavir
62669Hiv-1 PR Mutant in Complex With Nelfinavir
60188Crystal Structure of Lysine Sulfonamide Inhibitor Reveals the Displacement of the Conserved Flap Water Molecule in Hiv-1 Protease
59383Crystal Structure of Kb73 Bound to Hiv-1 Protease
59384Crystal Structure of Kk44 Bound to Hiv-1 Protease
59385Crystal Structure of Lopinavir Bound to Wild Type Hiv-1 Protease
62673Hiv-1 PR Mutant in Complex With Nelfinavir
62674Hiv-1 PR Mutant in Complex With Nelfinavir
65163Hiv-1 PR Mutant in Complex With Nelfinavir
63913Hiv-1 Protease Mutant D30n With Potent Antiviral Inhibitor Grl-98065
63914Hiv-1 Protease Mutant I50v With Potent Antiviral Inhibitor Grl-98065
63915Hiv-1 Protease Mutant V82a With Potent Antiviral Inhibitor Grl-98065
63916Hiv-1 Protease Mutant I84v With Potent Antiviral Inhibitor Grl-98065
65545The Influence of I47a Mutation on Reduced Susceptibility to the Protease Inhibitor Lopinavir
63917Crystal Structure of Protease Inhibitor, Mit-1-ac86 in Complex With Wild Type Hiv-1 Protease
63918Crystal Structure of Protease Inhibitor, Mit-1-ac87 in Complex With Wild Type Hiv-1 Protease
63919Crystal Structure of Protease Inhibitor, Mit-1-kk80 in Complex With Wild Type Hiv-1 Protease
63920Crystal Structure of Protease Inhibitor, Mit-1-kk81 in Complex With Wild Type Hiv-1 Protease
63921Crystal Structure of Protease Inhibitor, Mit-2-ad94 in Complex With Wild Type Hiv-1 Protease
63922Crystal Structure of Protease Inhibitor, Mit-2-ad93 in Complex With Wild Type Hiv-1 Protease
63923Crystal Structure of Protease Inhibitor, Mit-2-kc08 in Complex With Wild Type Hiv-1 Protease
63924Crystal Structure of Protease Inhibitor, Mit-2-kb98 in Complex With Wild Type Hiv-1 Protease
63925Crystal Structure of Protease Inhibitor, Mit-2-ad86 in Complex With Wild Type Hiv-1 Protease
65553Crystal Structure of Hiv-1 Protease Complexed With Pl-100
63777Hiv-1 Protease in Complex With a Multiple Decorated Pyrrolidine-based Inhibitor
63778Hiv-1 Protease in Complex With a Iodo Decorated Pyrrolidine- Based Inhibitor
63779Hiv-1 Protease in Complex With a Chloro Decorated Pyrrolidine-based Inhibitor
66402I84v Hiv-1 Protease Mutant in Complex With a Carbamoyl Decorated Pyrrolidine-based Inhibitor
66403I50v Hiv-1 Protease Mutant in Complex With a Carbamoyl Decorated Pyrrolidine-based Inhibitor
66404I84v Hiv-1 Protease in Complex With a Amino Decorated Pyrrolidine-based Inhibitor
66548I50v Hiv-1 Protease in Complex With an Amino Decorated Pyrrolidine- Based Inhibitor
4714Hiv-1 Protease Complex With U100313 ([3-[[3-[cyclopropyl [4-hydroxy- 2oxo-6-[1-(phenylmethyl)propyl]-2h-pyran-3-yl] Methyl]phenyl]amino]- 3-oxo-propyl]carbamic Acid Tert-butyl Ester)
64505Two-carbon-elongated Hiv-1 Protease Inhibitors With a Tertiary-alcohol-containing Transition-state Mimic
64506Two-carbon-elongated Hiv-1 Protease Inhibitors With a Tertiary-alcohol-containing Transition-state Mimic
78684Hiv-1 Protease Inhibitors Containing a Tertiary Alcohol in the Transition-state Mimic With Improved Cell-based Antiviral Activity
78685Hiv-1 Protease Inhibitors Containing a Tertiary Alcohol in the Transition-state Mimic With Improved Cell-based Antiviral Activity
63959Wild Type Hiv-1 Protease With Potent Antiviral Inhibitor Grl-98065
65219The Influence of I47a Mutation on Reduced Susceptibility to the Protease Inhibitor Lopinavir
69386Hiv-1 Protease in Complex With a Dimethylallyl Decorated Pyrrolidine Based Inhibitor (Hexagonal Space Group)
70349Structure of Hiv-1 Protease in Complex With Potent Inhibitor Kni-272 Determined by Neutron Crystallography
80389Crystal Structure of Hiv-1 Protease Complexed With Kni-1689
6394a NEW Class of Hiv-1 Protease Inhibitor: the Crystallographic Structure, Inhibition and Chemical Synthesis of an Aminimide Peptide Isostere
61421Hiv-1 Protease Complexed With Gem-diol-amine Tetrahedral Intermediate Nlltqi
61422Hiv-1 Protease Mutant I54v Complexed With Gem-diol-amine Intermediate Nlltqi
66440I84v Hiv-1 Protease in Complex With a Pyrrolidine Diester
66441Hiv-1 Protease in Complex With a Isobutyl Decorated Oligoamine
66442Hiv-1 Protease in Complex With a Benzyl Decorated Oligoamine
68388Hiv-1 Protease in Complex With a Three Armed Pyrrolidine Derivative
63520Cystal Structure of Hiv-1 Active Site Mutant D25n and P2-nc Analog Inhibitor
63521Cystal Structure of Hiv-1 Active Site Mutant D25n and Inhibitor Darunavir
70361Hiv-1 Protease in Complex With a Dimethylallyl Decorated Pyrrolidine Based Inhibitor (Orthorombic Space Group)
64714Effect of Flap Mutations on Structure of Hiv-1 Protease and Inhibition by Saquinavir and Darunavir
64715Crystal Structure of Hiv-1 Mutant I50v and Inhibitor Saquinavira
64794Crystal Structure of Hiv-1 Mutant I54m and Inhibitor Saquinavir
64718Crystal Structure of Hiv-1 Mutant I54v and Inhibitor Saquina
64719Crystal Structure of Hiv-1 Mutant I54m and Inhibitor Darunavir
64720Crystal Structure of Hiv-1 Mutant I54v and Inhibitor Darunavia
67036Wild Type Hiv-1 Protease With Potent Antiviral Inhibitor Grl-0255a
72588Wild Type Hiv-1 Protease With Potent Antiviral Inhibitor Grl-0105a
76405Crystal Structure of the Inhibitor Amprenavir (Apv) in Complex With a Multi-drug Resistant Hiv-1 Protease Variant (L10ig48vi54vv64iv82a)refer: Flap+ in Citation
76407Crystal Structure of the Inhibitor Darunavir (Drv) in Complex With a Multi-drug Resistant Hiv-1 Protease Variant (L10fg48vi54vv64iv82a) (Refer: Flap+ in Citation.)
76408Crystal Structure of the Wild Type Hiv-1 Protease With the Inhibitor, Amprenavir
76409Crystal Structure of the Inhibitor Atazanavir (Atv) in Complex With a Multi-drug Resistance Hiv-1 Protease Variant (L10ig48vi54vv64iv82a) Refer: Flap+ in Citation
76410Crystal Structure of the Wild-type Hiv-1 Protease With the Inhibitor, Nelfinavir
76411Crystal Structure of Wild-type HIV Protease in Complex With the Inhibitor, Atazanavir
76412Crystal Structure of the Inhibitor Nelfinavir (Nfv) in Complex With a Multi-drug Resistant Hiv-1 Protease Variant (L10ig48vi54vv64iv82a) (Refer: Flap+ in Citation)
76413Crystal Structure of Wild-type HIV Protease in Complex With the Inhibitor, Atazanavir
76414Crystal Structure of Inhibitor Saquinavir (Sqv) Complexed With the Multidrug Hiv-1 Protease Variant L63pv82ti84v
76415Crystal Structure of Nelfinavir (Nfv) Complexed With a Multidrug Variant (Act) (V82ti84v) of Hiv-1 Protease
76416Crystal Structure of Atazanavir (Atv) in Complex With a Multidrug Hiv- 1 Protease (V82ti84v)
76417Crystal Structure of Amprenavir (Apv) in Complex With a Drug Resistant Hiv-1 Protease Variant (I50la71v)
76418Crystal Structure of Atazanavir (Atv) in Complex With I50la71v Drug- Resistant Hiv-1 Protease
76419Crystal Structure of I50la71v Mutant of Hiv-1 Protease in Complex With Inhibitor Darunavir
70417Structure of Hiv-1 Protease in Complex With Potent Inhibitor Kni-272 Determined by High Resolution X-ray Crystallography
72913HIV Protease Inhibitors With Pseudo-symmetric Cores
72914HIV Protease, Pseudo-symmetric Inhibitors
72915HIV Protease, Pseudo-symmetric Inhibitors
80631Crystal Structure of Protease Inhibitor, Kb60 in Complex With Wild Type Hiv-1 Protease
80632Crystal Structure of Protease Inhibitor, Kb62 in Complex With Wild Type Hiv-1 Protease
80633Crystal Structure of Protease Inhibitor, Ad78 in Complex With Wild Type Hiv-1 Protease
73369Crystal Structure of Wild Type Hiv-1 Protease With Novel P1'-ligand Grl-02031
58324Conserved Folding in Retroviral Proteases. Crystal Structure of a Synthetic Hiv-1 Protease
77049Crystal Structure of Wild Type Hiv-1 Protease With Macrocyclic Inhibitor Grl-0216a
77050Co-crystal Structure of Hiv-1 Protease Bound to a Mutant Resistant Inhibitor Uic-98038
78436Crystal Structure of a Metallacarborane Inhibitor Bound to HIV Protease
78620Hiv-1 Protease Mutant G86a With Symmetric Inhibitor Dmp323
78621Hiv-1 Protease Mutant G86a With Darunavir
78622Hiv-1 Protease Mutant G86s With Darunavir
82614NEW Crystal Form of Hiv-1 Proteasesaquinavir Structure Reveals Carbamylation of N-terminal Proline
80488Crystal Structure of Hiv-1 Protease (Q7k, L33i, L63i) in Complex With Kni-10006
80811Crystal Structure of Hiv-1 Protease (Q7k, L33i, L63i) in Complex With Kni-10074
80489Crystal Structure of Hiv-1 Protease (Q7k, L33i, L63i) in Complex With Kni-10265
80269HIV Protease With Fragment 4D9 Bound
80273HIV Protease (Pr) With Inhibitor Tl-3 and Fragment HIT 4D9 by Soaking
80274HIV Protease (Pr) With Inhibitor Tl-3 Bound, and Dmsos in EXO Site
80275HIV Protease (Pr) Dimer With Inhibitor Tl-3 Bound and Fragment 1F1 in the Outsidetop of Flap
80276HIV Protease (Pr) Dimer With Inhibitor Tl-3 Bound and Fragment 2F4 in the Outside/top of Flap
83066HIV Protease Complexed With Compound 10B
89829X-ray Snapshot of Hiv-1 Protease in Action: Observation of Tetrahedral Intermediate and ITS Sihb With Catalytic Aspartate
86104Crystal Structure of Hiv-1 Protease Inhibitor Kc53 in Complex With Wild-type Protease
86105Crystal Structure of Hiv-1 Protease Inhibitor, Kc32 Complexed With Wild-type Protease
84429Wild Type Hiv-1 Protease With Antiviral Drug Amprenavir
84430Crystal Structure of Hiv-1 Protease Mutant V32i With Antiviral Drug Amprenavir
84431Crystal Structure of Hiv-1 Protease Mutant I50v With Antiviral Drug Amprenavir
84432Crystal Structure of Hiv-1 Protease Mutant I54m With Antiviral Drug Amprenavir
84433Crystal Structure of Hiv-1 Protease Mutant I84v With Antiviral Drug Amprenavir
84435Crystal Structure of Hiv-1 Protease Mutant I54v With Antiviral Drug Amprenavir
84436Crystal Structure of Hiv-1 Protease Mutant L90m With Antiviral Drug Amprenavir
85080Crystal Structure of Wild-type Hiv-1 Protease With NEW Oxatricyclic Designed Inhibitor Grl-0519a
89684Crystal Structures of Multidrug-resistant Clinical Isolate 769 Hiv-1 Protease Variants
89685Crystal Structures of Multidrug-resistant Clinical Isolate 769 Hiv-1 Protease Variants
89686Crystal Structures of Multidrug-resistant Clinical Isolate 769 Hiv-1 Protease Variants
89529Mdr769 Hiv-1 Protease Complexed With Maca Hepta-peptide
89530Mdr769 Hiv-1 Protease Complexed With Rtrh Hepta-peptide
89531Mdr769 Hiv-1 Protease Complexed With Rhin Hepta-peptide
89532Mdr769 Hiv-1 Protease Complexed With Prrt Hepta-peptide
89533Mdr769 Hiv-1 Protease Complexed With Tfpr Hepta-peptide
89534Mdr769 Hiv-1 Protease Complexed With P1p6 Hepta-peptide
89535Mdr769 Hiv-1 Protease Complexed With Ncp1 Hepta-peptide
89536Mdr769 Hiv-1 Protease Complexed With P2nc Hepta-peptide
89537Mdr769 Hiv-1 Protease Complexed With Cap2 Hepta-peptide
86145Wild Type Hiv-1 Protease With Antiviral Drug Saquinavir
88541Crystal Structure of Hiv-1 L76v Protease in Complex With the Protease Inhibitor Darunavir
58353X-ray Analysis of Hiv-1 Proteinase at 2.7 Angstroms Resolution Confirms Structural Homology Among Retroviral Enzymes
89695Crystal Structures of Multidrug-resistant Clinical Isolate 769 Hiv-1 Protease Variants
90013Hiv-1 Protease Mutant L76v With Darunavir
90014Hiv-1 Protease Mutant L76v Complexed With Saquinavir
12235Structural Studies of HIV and FIV Proteases Complexed Withan Efficient Inhibitor of FIV PR
54728Structure of Complex of Synthetic Hiv-1 Protease With a Stubtrate-based Inhibitor at 2.3 Angstroms Resolution
3200X-ray Crystal Structure of the HIV Protease Complex With L- 700,417, an Inhibitor With Pseudo C2 Symmetry
54778Crystallographic Analysis of a Complex Between Human Immunodeficiency Virus Type 1 Protease and Acetyl- Pepstatin at 2.0-angstroms Resolution
54817X-ray Crystallographic Structure of a Complex Between a Synthetic Protease of Human Immunodeficiency Virus 1 and a Substrate-based Hydroxyethylamine Inhibitor
5757Hiv-1 Proteaseu101935 Complex
3407Structure at 2.5-angstroms Resolution of Chemically Synthesized Human Immunodeficiency Virus Type 1 Protease Complexed With a Hydroxyethylene-based Inhibitor
54880Design, Activity and 2.8 Angstroms Crystal Structure of a C2 Symmetric Inhibitor Complexed to Hiv-1 Protease