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| MMDB Description | |
|---|---|
| 7610 | Hepatitis C Virus NS3 Proteinase |
| 47715 | HCV NS3 Protease Domain:ns4a Peptide Complex |
| 47718 | Hepatitis C Virus NS3 Helicase Domain Complexed With Single Stranded Sdna |
| 55654 | The Solution NMR Structure of the N-terminal Protease Domain of the Hepatitis C Virus (Hcv) Ns3-protein, From BK Strain, 20 Structures |
| 12849 | Hepatitis C Virus Ns5b RNA-dependent RNA Polymerase |
| 11626 | Crystal Structure of the RNA-dependent RNA Polymerase of Hepatitis C Virus |
| 14085 | Crystal Structure of an Enzyme Complex From Hepatitis C Virus |
| 48748 | Inhibition of the Hepatitis C Virus Ns3/4a Protease. The Crystal Structures of Two Protease-inhibitor Complexes (Apo Structure) |
| 91064 | Structure of Hetero Complex of NON Structural Protein (Ns) of Hepatitis C Virus (Hcv) and Synthetic Peptidic Compound |
| 73562 | Inhibition of the Hepatitis C Virus Ns34a Protease. The Crystal Structures of Two Protease-inhibitor Complexes (Inhibitor II) |
| 91065 | Inhibition of the Hepatitis C Virus Ns34a Protease. The Crystal Structures of Two Protease-inhibitor Complexes (Inhibitor I) |
| 19189 | Hepatitis C Virus RNA Polymerase in Complex With GTP and Manganese |
| 19190 | Hepatitis C Virus RNA Polymerase in Complex With UTP and Manganese |
| 8513 | Structure of the Hepatitis C Virus RNA Helicase Domain |
| 49865 | BK Strain Hepatitis C Virus (Hcv) Ns3-ns4a |
| 24947 | Crystal Structure of HCV NS3 Protease Domain:ns4a Peptide Complex With Covalently Bound Inhibitor (Gw472467x) |
| 22380 | Hc-j4 RNA Polymerase Apo-form |
| 22381 | Hc-j4 RNA Polymerase Complexed With UTP |
| 22382 | Hc-j4 RNA Polymerase Complexed With Short RNA Template Strand |
| 22402 | Hepatitis C Virus RNA Polymerase in Complex With Non- Nucleoside Analogue Inhibitor |
| 22403 | Hepatitis C Virus RNA Polymerase in Complex With Non- Nucleoside Analogue Inhibitor |
| 7540 | Structure of HCV Protease (BK Strain) |
| 26788 | Crystal Structure of HCV Ns5b RNA Polymerase Complexed With a Novel Non-competitive Inhibitor |
| 11637 | Crystal Structure of the RNA Directed RNA Polymerase of Hepatitis C Virus |
| 29870 | M9A HCV Protease Complex With Pentapeptide Keto-amide Inhibitor |
| 30831 | Crystal Structure of HCV NS3 Protease Domain: Ns4a Peptide Complex With Covalently Bound Pyrrolidine-5,5-translactam Inhibitor |
| 31004 | Crystal Structure of the Hepatitis C Virus NS3 Protease in Complex With a Peptidomimetic Inhibitor |
| 32963 | Hepatitis C Virus Ns5b RNA-dependent RNA Polymerase Complex With Inhibitor Pha-00729145 |
| 33797 | Hepatitis C Virus Ns5b RNA-dependent RNA Polymerase Complex With Inhibitor Pha-00799585 |
| 39550 | Hepatitis C Protease Ns3-4a Serine Protease With Ketoamide Inhibitor Sch225724 Bound |
| 39551 | HCV NS3 Protease With Ns4a Peptide and a Covalently Bound Macrocyclic Ketoamide Compound |
| 39552 | HCV NS3 Protease Domain With a Ketoamide Inhibitor Covalently Bound |
| 37096 | Hepatitis C Virus Ns5b RNA Polymerase in Complex With a Covalent Inhibitor (5h) |
| 37097 | Hepatitis C Virus Ns5b RNA Polymerase in Complex With a Covalent Inhibitor (5x) |
| 37098 | Hepatitis C Virus Ns5b RNA Polymerase in Complex With a Covalent Inhibitor (5ee) |
| 34015 | Crystal Structure of Hepatitis C Virus Polymerase in Complex With an Allosteric Inhibitor (Compound 1) |
| 34016 | Crystal Structure of Hepatitis C Virus Polymerase in Complex With an Allosteric Inhibitor (Compound 2) |
| 40332 | X-ray Crystal Structure of Hepatitis C Virus RNA Dependent RNA Polymerase in Complex With Non-nucleoside Analogue Inhibitor |
| 40333 | X-ray Crystal Structure of Hepatitis C Virus RNA-dependent RNA Polymerase in Complex With Non-nucleoside Analogue Inhibitor |
| 40334 | X-ray Crystal Structure of Hepatitis C Virus RNA-dependent RNA Polymerase in Complex With Non-nucleoside Inhibitor |
| 43260 | Crystal Structure of HCV Ns5b RNA Polymerase Complexed With a Tetracyclic Inhibitor |
| 57987 | Two Hepatitis C Virus NS3 Helicase Domains Complexed With the Same Strand of DNA |
| 39248 | HCV NS3 Protease Domain With Ns4a Peptide and a Ketoamide Inhibitor With a P2 Norborane |
| 43747 | HCV NS3 Protease Domain With Ns4a Peptide and a Ketoamide Inhibitor With P1 and P2 Cyclopropylalannines |
| 37777 | HCV Ns3-4a Protease Domain Complexed With a Ketoamide Inhibitor, Sch446211 |
| 43795 | Crystal Structure of Ns5b BK Strain (Delta 24) in Complex With a 3-(1, 1-dioxo-2h-(1,2,4)-benzothiadiazin-3-yl)-4-hydroxy-2(1h)-quinolinone |
| 39957 | Structure of a Proline Sulfonamide Inhibitor Bound to HCV Ns5b Polymerase |
| 44971 | Hepatitis C Virus RNA-dependent RNA Polymerase Ns5b With Nni-2 Inhibitor |
| 44972 | Hepatitis C Virus RNA-dependent RNA Polymerase Ns5b With Nni-1 Inhibitor |
| 43836 | HCV Ns3-4a Protease Domain Complexed With a Macrocyclic Ketoamide Inhibitor, Sch419021 |
| 41014 | Crystal Structure of HCV Ns5b RNA Polymerase in Complex With Novel Class of Dihydropyrone-containing Inhibitor |
| 40561 | Structure of the Catalytic Domain of Hepatitis C Virus NS2 |
| 42881 | HCV Ns5b Allosteric Inhibitor Complex |
| 42882 | HCV Ns5b Allosteric Inhibitor Complex |
| 42307 | Novel Thiazolones as HCV Ns5b Polymerase Inhibitors: Further Designs, Synthesis, SAR and X-ray Complex Structure |
| 42965 | Isothiazoles as Active-site Inhibitors of HCV Ns5b Polymerase |
| 44573 | Crystal Structure of Hepatitis C Virus Polymerase in Complex With Inhibitor Sb655264 |
| 44574 | Crystal Structure of Hepatitis C Virus Polymerase in Complex With Inhibitor Sb698223 |
| 69364 | NMR Structure of Hepatitis C Virus NS3 Serine Protease Complexed With the Non-covalently Bound Phenethylamide Inhibitor |
| 44653 | Thiazolone-acylsulfonamides as Novel HCV Ns5b Polymerase Allosteric Inhibitors: Convergence of Structure-based Drug Design and X-ray Crystallographic Study |
| 59175 | Crystal Structure of the S139a Mutant of Hepatitis C Virus Ns34a Protease |
| 53948 | Structure of Hepatitis C Viral NS3 Protease Domain Complexed With Ns4a Peptide and Ketoamide Sch476776 |
| 53949 | Discovery of the HCV Ns34a Protease Inhibitor Sch503034. KEY Steps in Structure-based Optimization |
| 53951 | Structure of NS3 Complexed With a Ketoamide Inhibitor Sch491762 |
| 53952 | Structure of the HCV Ns34a Protease Inhibitor Cvs4819 |
| 53953 | Structure of Hepatitis C Viral NS3 Protease Domain Complexed With Ns4a Peptide and Ketoamide Sch571696 |
| 53954 | Structure of Hepatitis C Viral NS3 Protease Domain Complexed With Ns4a Peptide and Ketoamide Sch503034 |
| 46420 | Crystal Structure of HCV Ns3-4a R155k Muntant |
| 62225 | Crystal Structure of Hepatitis C Virus Ns3.4a Protease |
| 59439 | Structure of HCV Ns5b Bound to an Anthranilic Acid Inhibitor |
| 59441 | Structure of HCV Ns5b Bound to an Anthranilic Acid Inhibitor |
| 66110 | Crystal Structure of HCV Ns3-4a V36m Mutant |
| 75995 | Crystal Structure of Hepatitis C Virus Ns5b Polymerase in Complex With Thienopyrrole-based Finger-loop Inhibitors |
| 75875 | Crystal Structure of Hepatitis C Virus Ns5b Polymerase From 1B Genotype in Complex With a Non-nucleoside Inhibitor |
| 84955 | Identification of Novel Allosteric Inhibitors of Hepatitis C Virus Ns5b Polymerase Thumb Domain (Site II) by Structure-based Design |
| 82426 | Crystal Structure of HCV NS3 Protease With a Boronate Inhibitor |
| 82427 | Crystal Structure of HCV NS3 Protease With a Boronate Inhibitor |
| 89614 | Hcv-j4 Ns5b Polymerase Orthorhombic Crystal Form |
| 89615 | Hcv-j4 Ns5b Polymerase Point Mutant Orthorhombic Crystal Form |
| 89616 | Hcv-j4 Ns5b Polymerase Trigonal Crystal Form |
| 89617 | Hcv-h77 Ns5b APO Polymerase |
| 89618 | Hcv-h77 Ns5b Polymerase Complexed With GTP |
| 87425 | Structure of Mk-3281, a Potent Non-nucleoside Finger-loop Inhibitor, in Complex With the Hepatitis C Virus Ns5b Polymerase |
| 70072 | Crystal Structure of Hepatitis C Virus NS3 Helicase With a Novel Inhibitor |
| 70648 | Structure of Hepatitis C Virus Ns5b Polymerase in a NEW Crystal Form |
| 68629 | Crystal Structure of HCV Ns5b Polymerase With a Novel Pyridazinone Inhibitor |
| 68631 | Crystal Structure of HCV Ns5b Polymerase With a Novel Pyridazinone Inhibitor |
| 68632 | Crystal Structure of HCV Ns5b Polymerase With a Novel Pyridazinone Inhibitor |
| 69929 | Crystal Structure of HCV Ns5b Polymerase With a Novel Pyridazinone Inhibitor |
| 63856 | Crystal Structure of Hepatitis C Virus RNA-dependent RNA Polymerase Ns5b in Complex With Small Molecule Fragments |
| 63857 | Crystal Structure of Hepatitis C Virus RNA-dependent RNA Polymerase Ns5b in Complex With Small Molecule Fragments |
| 63858 | Crystal Structure of Hepatitis C Virus RNA-dependent RNA Polymerase Ns5b in Complex With Optimized Small Molecule Fragments |
| 63859 | Crystal Structure of Hepatitis C Virus RNA-dependent RNA Polymerase Ns5b in Complex With Optimized Small Molecule Fragments |
| 63860 | Crystal Structure of Hepatitis C Virus RNA-dependent RNA Polymerase Ns5b in Complex With Optimized Small Molecule Fragments |
| 63861 | Crystal Structure of Hepatitis C Virus RNA-dependent RNA Polymerase Ns5b in Complex With Optimized Small Molecule Fragments |
| 69530 | Crystal Structure of HCV Ns5b Polymerase With a Novel Pyridazinone Inhibitor |
| 70811 | HCV Polymerase in Complex With a 1,5 Benzodiazepine Inhibitor |
| 70976 | Crystal Structure of HCV Ns5b Polymerase With a Novel Pyridazinone Inhibitor |
| 70977 | Crystal Structure of HCV Ns5b Polymerase With a Novel Pyridazinone Inhibitor |
| 72735 | Crystal Structure of HCV Ns5b Polymerase With a Novel Benzisothiazole Inhibitor |
| 72738 | Crystal Structure of HCV Ns5b Polymerase With a Novel Pyridazinone Inhibitor |
| 76047 | Crystal Structure of HCV Ns5b Polymerase With a Novel Pyridazinone Inhibitor |
| 69565 | Structure of HCV Ns3-4a Protease With an Inhibitor Derived From a Boronic Acid |
| 69868 | Hepatitis C Virus Polymerase Ns5b (BK 1-570) With Hcv-796 Inhibitor |
| 69869 | Hepatitis C Virus Polymerase Ns5b (Con1 1-570) With Hcv-796 Inhibitor |
| 70154 | Crystal Structure of HCV Ns5b RNA Polymerase in Complex With |
| 76565 | Hepatitis C Virus Polymerase Ns5b (BK 1-570) With Thiazine Inhibitor |
| 77486 | HCV Ns5b Polymerase in Complex With 1,5 Benzodiazepine Inhibitor 1B |
| 77487 | HCV Ns5b Polymerase in Complex With 1,5 Benzodiazepine Inhibitor 4C |
| 73355 | HCV Ns5b Polymerase in Complex With 1,5 Benzodiazepine Inhibitor (R)- 11D |
| 78548 | Crystal Structure of HCV Ns5b Polymerase With a Novel Monocyclic Dihydropyridinone Inhibitor |
| 78561 | Crystal Structure of HCV Ns5b Polymerase in Complex With a Novel Bicyclic Dihydro-pyridinone Inhibitor |
| 76578 | Hepatitis C Virus Polymerase Ns5b With Thiazine Inhibitor 2 |
| 76579 | Hepatitis C Virus Polymerase Ns5b With Saccharin Inhibitor |
| 76580 | Hepatitis C Virus Polymerase Ns5b With Saccharin Inhibitor 1 |
| 77310 | Crystal Structure of HCV Ns5b 1B With (1,1-dioxo-2h-[1,2, 4]benzothiadiazin-3-yl) Azolo[1,5-a]pyrimidine Derivative |
| 76587 | HCV Ns5b Polymerase Complex With a Substituted Benzothiadizine |
| 82310 | HCV Ns5b Genotype 1A in Complex With 1,5 Benzodiazepine Inhi |
| 82311 | HCV Ns5b Polymerase Genotype 1B in Complex With 1,5 Benzodiazepine 6 |
| 78600 | Crystal Structure of HCV Ns5b Polymerase With a Novel Monocyclic Dihydro-pyridinone Inhibitor |
| 80664 | HCV Ns3ns4a Complexed With Non-covalent Macrocyclic Compound Tmc435 |
| 80665 | The HCV Ns3ns4a Protease APO Structure |
| 79488 | HCV NS3 Protease Domain With Ketoamide Inhibitor |
| 85757 | HCV NS3 Protease Domain With P1-p3 Macrocyclic Ketoamide Inhibitor |
| 79637 | Three Conformational Snapshots of the Hepatitis C Virus NS3 Helicase Reveal a Ratchet Translocation Mechanism |
| 79638 | Three Conformational Snapshots of the Hepatitis C Virus NS3 Helicase Reveal a Ratchet Translocation Mechanism |
| 79639 | Three Conformational Snapshots of the Hepatitis C Virus NS3 Helicase Reveal a Ratchet Translocation Mechanism |
| 79640 | Three Conformational Snapshots of the Hepatitis C Virus NS3 Helicase Reveal a Ratchet Translocation Mechanism |
| 79641 | Three Conformational Snapshots of the Hepatitis C Virus NS3 Helicase Reveal a Ratchet Translocation Mechanism |
| 80991 | Inhibitors of Hepatitis C Virus Polymerase: Synthesis and Characterization of Novel 6-fluoro-n-[2-hydroxy-1(s)-benzam |
| 88027 | HCV Ns3-4a Protease Domain With Ketoamide Inhibitor Narlaprevir |
| 88808 | HCV Ns3-4a Protease Domain With a Ketoamide Inhibitor Derivative of Boceprevir Bound |
| 86428 | Crystal Structure of HCV Ns34a Protease in Complex With Itmn-191 |
| 86429 | Avoiding Drug Resistance Against HCV Ns34a Protease Inhibitors |
| 86430 | Crystal Structure of HCV Ns34a Protease in Complex With N-terminal Product 4b5a |
| 86431 | Crystal Structure of HCV Ns34a Protease in Complex With N-terminal Product 5a5b |
| 83649 | Hepatitis C Virus Polymerase Ns5b (Bk) With Amide Bioisostere Thumb Site Inhibitor |
| 85780 | Crystal Structure of HCV Ns5b Polymerase |
| 85781 | Crystal Structure of HCV Ns5b Polymerase |
| 87714 | Visualizing Atp-dependent RNA Translocation by the NS3 Helicase From HCV |
| 87715 | Visualizing Atp-dependent RNA Translocation by the NS3 Helicase From HCV |
| 87716 | Visualizing Atp-dependent RNA Translocation by the NS3 Helicase From HCV |
| 87717 | Visualizing Atp-dependent RNA Translocation by the NS3 Helicase From HCV |
| 86656 | HCV Ns34a in Complex With Ligand 3 |
| 88238 | Crystal Structure of HCV Ns3ns4a Protease Complexed With BI 201335 |
| 88239 | Crystal Structure of HCV Ns3ns4a Protease Complexed With Des-bromine Analogue of BI 201335 |
| 86360 | HCV Ns5b With a Bound Quinolone Inhibitor |
| 90174 | Crystal Structure of the Hepatitis C Virus Ns5b RNA-dependent RNA Polymerase Complex With (2e)-3-(4-{[(1-{[(13-cyclohexyl-6-oxo-6,7- Dihydro-5h-indolo[1,2-d][1,4]benzodiazepin-10-yl) Carbonyl]amino}cyclopentyl)carbonyl]amino}phenyl)prop-2-enoic Acid |
| 90032 | Crystal Structure of the Hepatitis C Virus Ns5b RNA-dependent RNA Polymerase Complex With (2e)-3-(4-{[(1-{[(13-cyclohexyl-6-oxo-6,7- Dihydro-5h-indolo[1,2-d][1,4]benzodiazepin-10-yl) Carbonyl]amino}cyclopentyl)carbonyl]amino}phenyl)prop-2-enoic Acid and (2r)-4-(2,6-dimethoxypyrimidin-4-yl)-1-[(4-ethylphenyl)sulfonyl]- N-(4-methoxybenzyl)piperazine-2-carboxamide |
| 90033 | Crystal Structure of the Hepatitis C Virus Ns5b RNA-dependent RNA Polymerase Complex With (2e)-3-(4-{[(1-{[(13-cyclohexyl-6-oxo-6,7- Dihydro-5h-indolo[1,2-d][1,4]benzodiazepin-10-yl) Carbonyl]amino}cyclopentyl)carbonyl]amino}phenyl)prop-2-enoic Acid and (2r)-4-(2,6-dimethoxypyrimidin-4-yl)-n-(4-methoxybenzyl)-1-{[4- (Trifluoromethoxy)phenyl]sulfonyl}piperazine-2-carboxamide |
| 90034 | Crystal Structure of the Hepatitis C Virus Ns5b RNA-dependent RNA Polymerase Complex With (2e)-3-(4-{[(1-{[(13-cyclohexyl-6-oxo-6,7- Dihydro-5h-indolo[1,2-d][1,4]benzodiazepin-10-yl) Carbonyl]amino}cyclopentyl)carbonyl]amino}phenyl)prop-2-enoic Acid and (2r)-4-(6-chloropyridazin-3-yl)-n-(4-methoxybenzyl)-1-{[4- (Trifluoromethoxy)phenyl]sulfonyl}piperazine-2-carboxamide |
| 90035 | Crystal Structure of the Hepatitis C Virus Ns5b RNA-dependent RNA Polymerase Complex With (2e)-3-(4-{[(1-{[(13-cyclohexyl-6-oxo-6,7- Dihydro-5h-indolo[1,2-d][1,4]benzodiazepin-10-yl) Carbonyl]amino}cyclopentyl)carbonyl]amino}phenyl)prop-2-enoic Acid and N-cyclopropyl-6-[(3r)-3-{[4-(trifluoromethoxy)benzyl]carbamoyl}- 4-{[4-(trifluoromethoxy)phenyl]sulfonyl}piperazin-1-yl]pyridazine-3- Carboxamide |
| 90036 | Crystal Structure of the Hepatitis C Virus Ns5b RNA-dependent RNA Polymerase Genotype 1A Complex With N-cyclopropyl-6-[(3r)-3-{[4- (Trifluoromethoxy)benzyl]carbamoyl}-4-{[4-(trifluoromethoxy) Phenyl]sulfonyl}piperazin-1-yl]pyridazine-3-carboxamide |
| 90037 | Crystal Structure of the Hepatitis C Virus Ns5b RNA-dependent RNA Polymerase Genotype 1A Complex With N-[(2s)-butan-2-yl]-6-[(3r)-3- {[4-(trifluoromethoxy)benzyl]carbamoyl}-4-{[4-(trifluoromethoxy) Phenyl]sulfonyl}piperazin-1-yl]pyridazine-3-carboxamide |
| 90340 | Molecular Mechanisms of Viral and Host-cell Substrate Recognition by HCV Ns34a Protease |
| 90341 | Molecular Mechanisms of Viral and Host-cell Substrate Recognition by HCV Ns34a Protease |
| 90342 | Molecular Mechanisms of Viral and Host-cell Substrate Recognition by HCV Ns34a Protease |
| 58609 | Crystal Structure of RNA Helicase From Genotype 1B Hepatitis C Virus: Mechanism of Unwinding Duplex RNA |