Secretase targets for Alzheimer's disease: identification and therapeutic potential

J Med Chem. 2001 Jun 21;44(13):2039-60. doi: 10.1021/jm0004897.
No abstract available

Publication types

  • Review

MeSH terms

  • Alzheimer Disease / drug therapy
  • Alzheimer Disease / enzymology*
  • Alzheimer Disease / genetics*
  • Amino Acid Sequence
  • Amyloid / metabolism
  • Amyloid Precursor Protein Secretases
  • Animals
  • Aspartic Acid Endopeptidases
  • Endopeptidases / genetics*
  • Humans
  • Isoenzymes / genetics
  • Molecular Sequence Data

Substances

  • Amyloid
  • Isoenzymes
  • Amyloid Precursor Protein Secretases
  • Endopeptidases
  • Aspartic Acid Endopeptidases
  • BACE1 protein, human