4-[2-[Methyl(2-phenethyl)amino]-2-oxoethyl]-8-(phenylmethoxy)-2- naphthalenecarboxylic acid: a high affinity, competitive, orally active leukotriene B4 receptor antagonist

J Med Chem. 1992 Oct 30;35(22):4253-5. doi: 10.1021/jm00100a034.
No abstract available

MeSH terms

  • Administration, Oral
  • Animals
  • Binding, Competitive
  • Guinea Pigs
  • Humans
  • In Vitro Techniques
  • Leukotriene B4 / metabolism*
  • Macaca fascicularis
  • Naphthols / pharmacology*
  • Neutrophils / drug effects
  • Phenethylamines / pharmacology*
  • Radioligand Assay
  • Receptors, Immunologic / antagonists & inhibitors*
  • Receptors, Leukotriene B4

Substances

  • Naphthols
  • Phenethylamines
  • Receptors, Immunologic
  • Receptors, Leukotriene B4
  • RG 14893
  • Leukotriene B4