2. Metabolic Enzyme/Protease
  3. MMP
  4. MMP-7-IN-1

MMP-7-IN-1 is a potent and selective inhibitor of MMP-7 over MMP-1, -2, -3, -8, -9, -13 with an IC50 value of 10 nM. MMP-7 is a potential target for diseases including cancer and fibrosis.

For research use only. We do not sell to patients.

MMP-7-IN-1 Chemical Structure

MMP-7-IN-1 Chemical Structure

CAS No. : 2865097-05-6

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5 mg USD 650 In-stock
10 mg USD 1080 In-stock
25 mg USD 2100 In-stock
50 mg USD 3160 In-stock
100 mg USD 4750 In-stock
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This product is a controlled substance and not for sale in your territory.

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Based on 1 publication(s) in Google Scholar

MMP-7-IN-1 Related Antibodies

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Description

MMP-7-IN-1 is a potent and selective inhibitor of MMP-7 over MMP-1, -2, -3, -8, -9, -13 with an IC50 value of 10 nM. MMP-7 is a potential target for diseases including cancer and fibrosis[1].

IC50 & Target[1]

MMP-7

10 nM (IC50)

Molecular Weight

769.23

Formula

C31H44ClF3N6O9S
CAS No.
Appearance

Solid

Color

White to off-white

SMILES

ClC1=CC=C(C=C1C(F)(F)F)S(N[C@@H](CCC(NCC(N[C@H](C(N[C@H](C(N2CCC[C@H]2CC(N)=O)=O)C(C)C)=O)CC(C)C)=O)=O)C(O)=O)(=O)=O
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

-20°C, sealed storage, away from moisture and light

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)

Solvent & Solubility
In Vitro: 

DMSO : 100 mg/mL (130.00 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 1.3000 mL 6.5000 mL 13.0000 mL
5 mM 0.2600 mL 1.3000 mL 2.6000 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
×
Volume
×
Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

×
Volume (start)

V1

=
Concentration (final)

C2

×
Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

g

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
Purity & Documentation

Purity: 99.68%

COA (247 KB) HNMR (262 KB) LCMS (99 KB)

Handling Instructions (2659 KB)
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 1.3000 mL 6.5000 mL 13.0000 mL 32.5000 mL
5 mM 0.2600 mL 1.3000 mL 2.6000 mL 6.5000 mL
10 mM 0.1300 mL 0.6500 mL 1.3000 mL 3.2500 mL
15 mM 0.0867 mL 0.4333 mL 0.8667 mL 2.1667 mL
20 mM 0.0650 mL 0.3250 mL 0.6500 mL 1.6250 mL
25 mM 0.0520 mL 0.2600 mL 0.5200 mL 1.3000 mL
30 mM 0.0433 mL 0.2167 mL 0.4333 mL 1.0833 mL
40 mM 0.0325 mL 0.1625 mL 0.3250 mL 0.8125 mL
50 mM 0.0260 mL 0.1300 mL 0.2600 mL 0.6500 mL
60 mM 0.0217 mL 0.1083 mL 0.2167 mL 0.5417 mL
80 mM 0.0163 mL 0.0813 mL 0.1625 mL 0.4063 mL
100 mM 0.0130 mL 0.0650 mL 0.1300 mL 0.3250 mL
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MMP-7-IN-1 Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

MMP-7-IN-12865097-05-6MMPMatrix metalloproteinasesselectiveserumHLMInhibitorinhibitorinhibit

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