Compile Data Set for Download or QSAR

Found 1051 hits with Last Name = 'abadi' and Initial = 'ah'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Cannabinoid receptor 1 (Homo sapiens (Human))	BDBM50516776 (CHEMBL4437741) Show SMILES CCCCCn1c2ccccc2s\c1=N\C(=O)C12CC3CC(CC(C3)C1)C2 |TLB:20:21:18.19.24:25,THB:20:19:25:26.21.22,22:21:18:24.23.25,22:23:18:26.20.21| Show InChI InChI=1S/C23H30N2OS/c1-2-3-6-9-25-19-7-4-5-8-20(19)27-22(25)24-21(26)23-13-16-10-17(14-23)12-18(11-16)15-23/h4-5,7-8,16-18H,2-3,6,9-15H2,1H3/b24-22+	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	0.100	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
German University in Cairo Curated by ChEMBL					Assay Description Displacement of [3H]CP55940 from recombinant human CB1R expressed in HEK293 cell membranes incubated for 90 mins by Cheng-Prusoff equation analysis				Eur J Med Chem 180: 154-170 (2019) Article DOI: 10.1016/j.ejmech.2019.07.002 BindingDB Entry DOI: 10.7270/Q2R214R1
					More data for this Ligand-Target Pair
Cannabinoid receptor 1 (Homo sapiens (Human))	BDBM50516789 (CHEMBL4559193) Show SMILES CCCCCn1c2ccccc2s\c1=N/C(=O)c1cccc2ccccc12 Show InChI InChI=1S/C23H22N2OS/c1-2-3-8-16-25-20-14-6-7-15-21(20)27-23(25)24-22(26)19-13-9-11-17-10-4-5-12-18(17)19/h4-7,9-15H,2-3,8,16H2,1H3/b24-23-	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	0.110	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
German University in Cairo Curated by ChEMBL					Assay Description Displacement of [3H]CP55940 from recombinant human CB1R expressed in HEK293 cell membranes incubated for 90 mins by Cheng-Prusoff equation analysis				Eur J Med Chem 180: 154-170 (2019) Article DOI: 10.1016/j.ejmech.2019.07.002 BindingDB Entry DOI: 10.7270/Q2R214R1
					More data for this Ligand-Target Pair
Cannabinoid receptor 1 (Homo sapiens (Human))	BDBM50516782 (CHEMBL4592199) Show SMILES CCCCCn1c2ccccc2s\c1=N/C(=O)c1cccc(c1)C(F)(F)F Show InChI InChI=1S/C20H19F3N2OS/c1-2-3-6-12-25-16-10-4-5-11-17(16)27-19(25)24-18(26)14-8-7-9-15(13-14)20(21,22)23/h4-5,7-11,13H,2-3,6,12H2,1H3/b24-19-	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	1	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
German University in Cairo Curated by ChEMBL					Assay Description Displacement of [3H]CP55940 from recombinant human CB1R expressed in HEK293 cell membranes incubated for 90 mins by Cheng-Prusoff equation analysis				Eur J Med Chem 180: 154-170 (2019) Article DOI: 10.1016/j.ejmech.2019.07.002 BindingDB Entry DOI: 10.7270/Q2R214R1
					More data for this Ligand-Target Pair
D(2) dopamine receptor (Homo sapiens (Human))	BDBM50216040 (3-(4-(4-(2-methoxyphenyl)piperazin-1-yl)butyl)quin...) Show SMILES COc1ccccc1N1CCN(CCCCn2cnc3ccccc3c2=O)CC1 Show InChI InChI=1S/C23H28N4O2/c1-29-22-11-5-4-10-21(22)26-16-14-25(15-17-26)12-6-7-13-27-18-24-20-9-3-2-8-19(20)23(27)28/h2-5,8-11,18H,6-7,12-17H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.20	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Cairo University Curated by ChEMBL					Assay Description Antagonist activity at human Dopamine receptor D2 isoform long expressed in HEK293 cells assessed as change in quinpirole-induced intracellular calci...				Bioorg Med Chem 15: 5811-8 (2007) Article DOI: 10.1016/j.bmc.2007.06.002 BindingDB Entry DOI: 10.7270/Q27M07MZ
					More data for this Ligand-Target Pair
Cannabinoid receptor 2 (Homo sapiens (Human))	BDBM50200170 (5-(4-chloro-3-methyl-phenyl)-1-(4-methyl-benzyl)-1...) Show SMILES Cc1ccc(Cn2nc(cc2-c2ccc(Cl)c(C)c2)C(=O)N[C@H]2[C@@]3(C)CC[C@H](C3)C2(C)C)cc1 |r| Show InChI InChI=1S/C29H34ClN3O/c1-18-6-8-20(9-7-18)17-33-25(21-10-11-23(30)19(2)14-21)15-24(32-33)26(34)31-27-28(3,4)22-12-13-29(27,5)16-22/h6-11,14-15,22,27H,12-13,16-17H2,1-5H3,(H,31,34)/t22-,27-,29+/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Similars	Article PubMed	1.80	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
German University in Cairo Curated by ChEMBL					Assay Description Displacement of [3H]-CP-55940 from human CB2 receptor expressed in HEK293 cell membranes after 90 mins by radioligand binding assay				Eur J Med Chem 122: 619-634 (2016) Article DOI: 10.1016/j.ejmech.2016.07.012 BindingDB Entry DOI: 10.7270/Q2057HX9
					More data for this Ligand-Target Pair
Cannabinoid receptor 2 (Homo sapiens (Human))	BDBM50516789 (CHEMBL4559193) Show SMILES CCCCCn1c2ccccc2s\c1=N/C(=O)c1cccc2ccccc12 Show InChI InChI=1S/C23H22N2OS/c1-2-3-8-16-25-20-14-6-7-15-21(20)27-23(25)24-22(26)19-13-9-11-17-10-4-5-12-18(17)19/h4-7,9-15H,2-3,8,16H2,1H3/b24-23-	PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	2	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
German University in Cairo Curated by ChEMBL					Assay Description Displacement of [3H]CP55940 from recombinant human CB2R expressed in HEK293 cell membranes incubated for 90 mins by Cheng-Prusoff equation analysis				Eur J Med Chem 180: 154-170 (2019) Article DOI: 10.1016/j.ejmech.2019.07.002 BindingDB Entry DOI: 10.7270/Q2R214R1
					More data for this Ligand-Target Pair
Cannabinoid receptor 1 (Homo sapiens (Human))	BDBM50200170 (5-(4-chloro-3-methyl-phenyl)-1-(4-methyl-benzyl)-1...) Show SMILES Cc1ccc(Cn2nc(cc2-c2ccc(Cl)c(C)c2)C(=O)N[C@H]2[C@@]3(C)CC[C@H](C3)C2(C)C)cc1 |r| Show InChI InChI=1S/C29H34ClN3O/c1-18-6-8-20(9-7-18)17-33-25(21-10-11-23(30)19(2)14-21)15-24(32-33)26(34)31-27-28(3,4)22-12-13-29(27,5)16-22/h6-11,14-15,22,27H,12-13,16-17H2,1-5H3,(H,31,34)/t22-,27-,29+/m1/s1	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Similars	Article PubMed	2	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
German University in Cairo Curated by ChEMBL					Assay Description Displacement of [3H]CP55940 from recombinant human CB1R expressed in HEK293 cell membranes incubated for 90 mins by Cheng-Prusoff equation analysis				Eur J Med Chem 180: 154-170 (2019) Article DOI: 10.1016/j.ejmech.2019.07.002 BindingDB Entry DOI: 10.7270/Q2R214R1
					More data for this Ligand-Target Pair
Cannabinoid receptor 2 (Homo sapiens (Human))	BDBM21281 ((11R)-2-methyl-11-(morpholin-4-ylmethyl)-3-(naphth...) Show SMILES Cc1c(C(=O)c2cccc3ccccc23)c2cccc3OC[C@@H](CN4CCOCC4)n1c23 |r| Show InChI InChI=1S/C27H26N2O3/c1-18-25(27(30)22-9-4-7-19-6-2-3-8-21(19)22)23-10-5-11-24-26(23)29(18)20(17-32-24)16-28-12-14-31-15-13-28/h2-11,20H,12-17H2,1H3/t20-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid PDB UniChem Patents Similars	PDB Article PubMed	2.10	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
German University in Cairo Curated by ChEMBL					Assay Description Displacement of [3H]-CP-55940 from human CB2 receptor expressed in HEK293 cell membranes after 90 mins by radioligand binding assay				Eur J Med Chem 122: 619-634 (2016) Article DOI: 10.1016/j.ejmech.2016.07.012 BindingDB Entry DOI: 10.7270/Q2057HX9
					More data for this Ligand-Target Pair				3D Structure (crystal)
Cannabinoid receptor 2 (Homo sapiens (Human))	BDBM50202519 (CHEMBL3909238) Show SMILES CCOC(=O)c1c(NC(=O)C23CC4CC(CC(C4)C2)C3)sc2CCCCc12 |THB:15:14:11:17.16.18,15:16:13.14.19:11,18:16:13:19.10.11,18:10:13:17.15.16| Show InChI InChI=1S/C22H29NO3S/c1-2-26-20(24)18-16-5-3-4-6-17(16)27-19(18)23-21(25)22-10-13-7-14(11-22)9-15(8-13)12-22/h13-15H,2-12H2,1H3,(H,23,25)	PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	2.20	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
German University in Cairo Curated by ChEMBL					Assay Description Displacement of [3H]-CP-55940 from human CB2 receptor expressed in HEK293 cell membranes after 90 mins by radioligand binding assay				Eur J Med Chem 122: 619-634 (2016) Article DOI: 10.1016/j.ejmech.2016.07.012 BindingDB Entry DOI: 10.7270/Q2057HX9
					More data for this Ligand-Target Pair
D(2) dopamine receptor (Homo sapiens (Human))	BDBM50216045 (2-(4-(4-(2-methoxyphenyl)-1-piperazinyl)butyl)-1,2...) Show SMILES O=C1N(CCCCN2CCN(CC2)c2ccccc2)S(=O)(=O)c2ccccc12 Show InChI InChI=1S/C21H25N3O3S/c25-21-19-10-4-5-11-20(19)28(26,27)24(21)13-7-6-12-22-14-16-23(17-15-22)18-8-2-1-3-9-18/h1-5,8-11H,6-7,12-17H2	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	4.10	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Cairo University Curated by ChEMBL					Assay Description Antagonist activity at human Dopamine receptor D2 isoform long expressed in HEK293 cells assessed as change in quinpirole-induced intracellular calci...				Bioorg Med Chem 15: 5811-8 (2007) Article DOI: 10.1016/j.bmc.2007.06.002 BindingDB Entry DOI: 10.7270/Q27M07MZ
					More data for this Ligand-Target Pair
D(2) dopamine receptor (Homo sapiens (Human))	BDBM50216046 (2-(4-(4-phenyl-1-piperazinyl)butyl)-1,2-benzisothi...) Show SMILES COc1ccccc1N1CCN(CCCCN2C(=O)c3ccccc3S2(=O)=O)CC1 Show InChI InChI=1S/C22H27N3O4S/c1-29-20-10-4-3-9-19(20)24-16-14-23(15-17-24)12-6-7-13-25-22(26)18-8-2-5-11-21(18)30(25,27)28/h2-5,8-11H,6-7,12-17H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	6.20	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Cairo University Curated by ChEMBL					Assay Description Antagonist activity at human Dopamine receptor D2 isoform long expressed in HEK293 cells assessed as change in quinpirole-induced intracellular calci...				Bioorg Med Chem 15: 5811-8 (2007) Article DOI: 10.1016/j.bmc.2007.06.002 BindingDB Entry DOI: 10.7270/Q27M07MZ
					More data for this Ligand-Target Pair
Cannabinoid receptor 2 (Homo sapiens (Human))	BDBM50202521 (CHEMBL3962080) Show SMILES CCc1c(cc(C)n1-c1ccccc1)C(=O)NC12CC3CC(CC(C3)C1)C2 |TLB:20:21:18.19.24:25,THB:20:19:25:26.21.22,22:21:18:24.23.25,22:23:18:26.20.21| Show InChI InChI=1S/C25H30N2O2/c1-18-16-21(25(29)19-8-3-2-4-9-19)12-13-22(18)26-24(28)17-20-10-7-15-27-14-6-5-11-23(20)27/h2-4,8-9,12-13,16,20,23H,5-7,10-11,14-15,17H2,1H3,(H,26,28)/t20-,23+/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	6.20	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
German University in Cairo Curated by ChEMBL					Assay Description Displacement of [3H]-CP-55940 from human CB2 receptor expressed in HEK293 cell membranes after 90 mins by radioligand binding assay				Eur J Med Chem 122: 619-634 (2016) Article DOI: 10.1016/j.ejmech.2016.07.012 BindingDB Entry DOI: 10.7270/Q2057HX9
					More data for this Ligand-Target Pair
Cannabinoid receptor 2 (Homo sapiens (Human))	BDBM50202511 (CHEMBL3982062) Show SMILES Cc1cc(C(=O)NC23CC4CC(CC(C4)C2)C3)c(C)n1-c1ccccc1 |TLB:10:11:8.9.14:15,THB:10:9:15:16.11.12,12:11:8:14.13.15,12:13:8:16.10.11| Show InChI InChI=1S/C23H28N2O/c1-15-8-21(16(2)25(15)20-6-4-3-5-7-20)22(26)24-23-12-17-9-18(13-23)11-19(10-17)14-23/h3-8,17-19H,9-14H2,1-2H3,(H,24,26)	PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	7.60	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
German University in Cairo Curated by ChEMBL					Assay Description Displacement of [3H]-CP-55940 from human CB2 receptor expressed in HEK293 cell membranes after 90 mins by radioligand binding assay				Eur J Med Chem 122: 619-634 (2016) Article DOI: 10.1016/j.ejmech.2016.07.012 BindingDB Entry DOI: 10.7270/Q2057HX9
					More data for this Ligand-Target Pair
Cannabinoid receptor 1 (Homo sapiens (Human))	BDBM21281 ((11R)-2-methyl-11-(morpholin-4-ylmethyl)-3-(naphth...) Show SMILES Cc1c(C(=O)c2cccc3ccccc23)c2cccc3OC[C@@H](CN4CCOCC4)n1c23 |r| Show InChI InChI=1S/C27H26N2O3/c1-18-25(27(30)22-9-4-7-19-6-2-3-8-21(19)22)23-10-5-11-24-26(23)29(18)20(17-32-24)16-28-12-14-31-15-13-28/h2-11,20H,12-17H2,1H3/t20-/m1/s1	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid PDB UniChem Patents Similars	Article PubMed	9.20	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
German University in Cairo Curated by ChEMBL					Assay Description Displacement of [3H]-CP-55940 from human CB1 receptor expressed in HEK293 cell membranes after 90 mins by radioligand binding assay				Eur J Med Chem 122: 619-634 (2016) Article DOI: 10.1016/j.ejmech.2016.07.012 BindingDB Entry DOI: 10.7270/Q2057HX9
					More data for this Ligand-Target Pair
Cannabinoid receptor 2 (Homo sapiens (Human))	BDBM50516776 (CHEMBL4437741) Show SMILES CCCCCn1c2ccccc2s\c1=N\C(=O)C12CC3CC(CC(C3)C1)C2 |TLB:20:21:18.19.24:25,THB:20:19:25:26.21.22,22:21:18:24.23.25,22:23:18:26.20.21| Show InChI InChI=1S/C23H30N2OS/c1-2-3-6-9-25-19-7-4-5-8-20(19)27-22(25)24-21(26)23-13-16-10-17(14-23)12-18(11-16)15-23/h4-5,7-8,16-18H,2-3,6,9-15H2,1H3/b24-22+	PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	12	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
German University in Cairo Curated by ChEMBL					Assay Description Displacement of [3H]CP55940 from recombinant human CB2R expressed in HEK293 cell membranes incubated for 90 mins by Cheng-Prusoff equation analysis				Eur J Med Chem 180: 154-170 (2019) Article DOI: 10.1016/j.ejmech.2019.07.002 BindingDB Entry DOI: 10.7270/Q2R214R1
					More data for this Ligand-Target Pair
D(3) dopamine receptor (Homo sapiens (Human))	BDBM50216044 (2-(4-(4-(3-a,a,a-trifluorotolyl)-1-piperazinyl)but...) Show SMILES FC(F)(F)c1cccc(c1)N1CCN(CCCCN2Cc3ccccc3C2=O)CC1 Show InChI InChI=1S/C23H26F3N3O/c24-23(25,26)19-7-5-8-20(16-19)28-14-12-27(13-15-28)10-3-4-11-29-17-18-6-1-2-9-21(18)22(29)30/h1-2,5-9,16H,3-4,10-15,17H2	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	14	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Cairo University Curated by ChEMBL					Assay Description Displacement of [3H]Spiperone from human Dopamine D3 receptor expressed in CHO cells				Bioorg Med Chem 15: 5811-8 (2007) Article DOI: 10.1016/j.bmc.2007.06.002 BindingDB Entry DOI: 10.7270/Q27M07MZ
					More data for this Ligand-Target Pair
Cannabinoid receptor 2 (Homo sapiens (Human))	BDBM50202514 (CHEMBL3930225) Show SMILES CCOC(=O)c1c(NC(=O)c2cccc3ccccc23)sc2CCCCc12 Show InChI InChI=1S/C22H21NO3S/c1-2-26-22(25)19-17-11-5-6-13-18(17)27-21(19)23-20(24)16-12-7-9-14-8-3-4-10-15(14)16/h3-4,7-10,12H,2,5-6,11,13H2,1H3,(H,23,24)	PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	17	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
German University in Cairo Curated by ChEMBL					Assay Description Displacement of [3H]-CP-55940 from human CB2 receptor expressed in HEK293 cell membranes after 90 mins by radioligand binding assay				Eur J Med Chem 122: 619-634 (2016) Article DOI: 10.1016/j.ejmech.2016.07.012 BindingDB Entry DOI: 10.7270/Q2057HX9
					More data for this Ligand-Target Pair
Cannabinoid receptor 2 (Homo sapiens (Human))	BDBM50202523 (CHEMBL3981080) Show SMILES CCc1c(cc(C)n1-c1ccccc1)C(=O)Nc1cccc2ccccc12 Show InChI InChI=1S/C24H22N2O/c1-3-23-21(16-17(2)26(23)19-12-5-4-6-13-19)24(27)25-22-15-9-11-18-10-7-8-14-20(18)22/h4-16H,3H2,1-2H3,(H,25,27)	PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	20	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
German University in Cairo Curated by ChEMBL					Assay Description Displacement of [3H]-CP-55940 from human CB2 receptor expressed in HEK293 cell membranes after 90 mins by radioligand binding assay				Eur J Med Chem 122: 619-634 (2016) Article DOI: 10.1016/j.ejmech.2016.07.012 BindingDB Entry DOI: 10.7270/Q2057HX9
					More data for this Ligand-Target Pair
Cannabinoid receptor 1 (Homo sapiens (Human))	BDBM50516797 (CHEMBL4576974) Show SMILES CCCCCn1c2ccccc2s\c1=N/C(=O)c1ccc(cc1)C(F)(F)F Show InChI InChI=1S/C20H19F3N2OS/c1-2-3-6-13-25-16-7-4-5-8-17(16)27-19(25)24-18(26)14-9-11-15(12-10-14)20(21,22)23/h4-5,7-12H,2-3,6,13H2,1H3/b24-19-	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	25	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
German University in Cairo Curated by ChEMBL					Assay Description Displacement of [3H]CP55940 from recombinant human CB1R expressed in HEK293 cell membranes incubated for 90 mins by Cheng-Prusoff equation analysis				Eur J Med Chem 180: 154-170 (2019) Article DOI: 10.1016/j.ejmech.2019.07.002 BindingDB Entry DOI: 10.7270/Q2R214R1
					More data for this Ligand-Target Pair
D(2) dopamine receptor (Homo sapiens (Human))	BDBM50216044 (2-(4-(4-(3-a,a,a-trifluorotolyl)-1-piperazinyl)but...) Show SMILES FC(F)(F)c1cccc(c1)N1CCN(CCCCN2Cc3ccccc3C2=O)CC1 Show InChI InChI=1S/C23H26F3N3O/c24-23(25,26)19-7-5-8-20(16-19)28-14-12-27(13-15-28)10-3-4-11-29-17-18-6-1-2-9-21(18)22(29)30/h1-2,5-9,16H,3-4,10-15,17H2	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	26	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Cairo University Curated by ChEMBL					Assay Description Antagonist activity at human Dopamine receptor D2 isoform long expressed in HEK293 cells assessed as change in quinpirole-induced intracellular calci...				Bioorg Med Chem 15: 5811-8 (2007) Article DOI: 10.1016/j.bmc.2007.06.002 BindingDB Entry DOI: 10.7270/Q27M07MZ
					More data for this Ligand-Target Pair
D(3) dopamine receptor (Homo sapiens (Human))	BDBM50216047 (2-(4-(4-phenyl-1-piperazinyl)butyl)-1-isoindolinon...) Show SMILES COc1ccccc1N1CCN(CCCCN2Cc3ccccc3C2=O)CC1 Show InChI InChI=1S/C23H29N3O2/c1-28-22-11-5-4-10-21(22)25-16-14-24(15-17-25)12-6-7-13-26-18-19-8-2-3-9-20(19)23(26)27/h2-5,8-11H,6-7,12-18H2,1H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	30	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Cairo University Curated by ChEMBL					Assay Description Displacement of [3H]Spiperone from human Dopamine D3 receptor expressed in CHO cells				Bioorg Med Chem 15: 5811-8 (2007) Article DOI: 10.1016/j.bmc.2007.06.002 BindingDB Entry DOI: 10.7270/Q27M07MZ
					More data for this Ligand-Target Pair
D(1B) dopamine receptor (Homo sapiens (Human))	BDBM50216052 (2-(4-(4-(4-chlorophenyl)-1-piperazinyl)butyl)-1-is...) Show SMILES Clc1ccc(cc1)N1CCN(CCCCN2Cc3ccccc3C2=O)CC1 Show InChI InChI=1S/C22H26ClN3O/c23-19-7-9-20(10-8-19)25-15-13-24(14-16-25)11-3-4-12-26-17-18-5-1-2-6-21(18)22(26)27/h1-2,5-10H,3-4,11-17H2	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	33.6	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Cairo University Curated by ChEMBL					Assay Description Displacement of [3H]SCH 23390 from human Dopamine D5 receptor expressed in HEK293				Bioorg Med Chem 15: 5811-8 (2007) Article DOI: 10.1016/j.bmc.2007.06.002 BindingDB Entry DOI: 10.7270/Q27M07MZ
					More data for this Ligand-Target Pair
D(2) dopamine receptor (Homo sapiens (Human))	BDBM50216047 (2-(4-(4-phenyl-1-piperazinyl)butyl)-1-isoindolinon...) Show SMILES COc1ccccc1N1CCN(CCCCN2Cc3ccccc3C2=O)CC1 Show InChI InChI=1S/C23H29N3O2/c1-28-22-11-5-4-10-21(22)25-16-14-24(15-17-25)12-6-7-13-26-18-19-8-2-3-9-20(19)23(26)27/h2-5,8-11H,6-7,12-18H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	34	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Cairo University Curated by ChEMBL					Assay Description Antagonist activity at human Dopamine receptor D2 isoform long expressed in HEK293 cells assessed as change in quinpirole-induced intracellular calci...				Bioorg Med Chem 15: 5811-8 (2007) Article DOI: 10.1016/j.bmc.2007.06.002 BindingDB Entry DOI: 10.7270/Q27M07MZ
					More data for this Ligand-Target Pair
D(3) dopamine receptor (Homo sapiens (Human))	BDBM50216048 (2-(4-(4-(2-methoxyphenyl)-1-piperazinyl)butyl)-1-i...) Show SMILES O=C1N(CCCCN2CCN(CC2)c2ccccc2)Cc2ccccc12 Show InChI InChI=1S/C22H27N3O/c26-22-21-11-5-4-8-19(21)18-25(22)13-7-6-12-23-14-16-24(17-15-23)20-9-2-1-3-10-20/h1-5,8-11H,6-7,12-18H2	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	35.8	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Cairo University Curated by ChEMBL					Assay Description Displacement of [3H]Spiperone from human Dopamine D3 receptor expressed in CHO cells				Bioorg Med Chem 15: 5811-8 (2007) Article DOI: 10.1016/j.bmc.2007.06.002 BindingDB Entry DOI: 10.7270/Q27M07MZ
					More data for this Ligand-Target Pair
D(2) dopamine receptor (Homo sapiens (Human))	BDBM50216045 (2-(4-(4-(2-methoxyphenyl)-1-piperazinyl)butyl)-1,2...) Show SMILES O=C1N(CCCCN2CCN(CC2)c2ccccc2)S(=O)(=O)c2ccccc12 Show InChI InChI=1S/C21H25N3O3S/c25-21-19-10-4-5-11-20(19)28(26,27)24(21)13-7-6-12-22-14-16-23(17-15-22)18-8-2-1-3-9-18/h1-5,8-11H,6-7,12-17H2	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	38	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Cairo University Curated by ChEMBL					Assay Description Displacement of [3H]Spiperone from human Dopamine receptor D2 isoform long expressed in HEK293 cells				Bioorg Med Chem 15: 5811-8 (2007) Article DOI: 10.1016/j.bmc.2007.06.002 BindingDB Entry DOI: 10.7270/Q27M07MZ
					More data for this Ligand-Target Pair
D(2) dopamine receptor (Homo sapiens (Human))	BDBM50216041 (3-(4-(4-(2-methoxyphenyl)-1-piperazinyl)butyl)quin...) Show SMILES O=c1n(CCCCN2CCN(CC2)c2ccccc2)cnc2ccccc12 Show InChI InChI=1S/C22H26N4O/c27-22-20-10-4-5-11-21(20)23-18-26(22)13-7-6-12-24-14-16-25(17-15-24)19-8-2-1-3-9-19/h1-5,8-11,18H,6-7,12-17H2	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	46	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Cairo University Curated by ChEMBL					Assay Description Displacement of [3H]Spiperone from human Dopamine receptor D2 isoform long expressed in HEK293 cells				Bioorg Med Chem 15: 5811-8 (2007) Article DOI: 10.1016/j.bmc.2007.06.002 BindingDB Entry DOI: 10.7270/Q27M07MZ
					More data for this Ligand-Target Pair
Cannabinoid receptor 2 (Homo sapiens (Human))	BDBM50202539 (CHEMBL3953330) Show SMILES CCc1c(cc(C)n1-c1ccccc1)C(=O)Nc1ccc2ccccc2c1 Show InChI InChI=1S/C24H22N2O/c1-3-23-22(15-17(2)26(23)21-11-5-4-6-12-21)24(27)25-20-14-13-18-9-7-8-10-19(18)16-20/h4-16H,3H2,1-2H3,(H,25,27)	PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	57	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
German University in Cairo Curated by ChEMBL					Assay Description Displacement of [3H]-CP-55940 from human CB2 receptor expressed in HEK293 cell membranes after 90 mins by radioligand binding assay				Eur J Med Chem 122: 619-634 (2016) Article DOI: 10.1016/j.ejmech.2016.07.012 BindingDB Entry DOI: 10.7270/Q2057HX9
					More data for this Ligand-Target Pair
Cannabinoid receptor 2 (Homo sapiens (Human))	BDBM50202515 (CHEMBL3921132) Show SMILES Cc1cc(C(=O)Nc2ccc3ccccc3c2)c(C)n1-c1ccccc1 Show InChI InChI=1S/C23H20N2O/c1-16-14-22(17(2)25(16)21-10-4-3-5-11-21)23(26)24-20-13-12-18-8-6-7-9-19(18)15-20/h3-15H,1-2H3,(H,24,26)	PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	58	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
German University in Cairo Curated by ChEMBL					Assay Description Displacement of [3H]-CP-55940 from human CB2 receptor expressed in HEK293 cell membranes after 90 mins by radioligand binding assay				Eur J Med Chem 122: 619-634 (2016) Article DOI: 10.1016/j.ejmech.2016.07.012 BindingDB Entry DOI: 10.7270/Q2057HX9
					More data for this Ligand-Target Pair
D(2) dopamine receptor (Homo sapiens (Human))	BDBM50216048 (2-(4-(4-(2-methoxyphenyl)-1-piperazinyl)butyl)-1-i...) Show SMILES O=C1N(CCCCN2CCN(CC2)c2ccccc2)Cc2ccccc12 Show InChI InChI=1S/C22H27N3O/c26-22-21-11-5-4-8-19(21)18-25(22)13-7-6-12-23-14-16-24(17-15-23)20-9-2-1-3-10-20/h1-5,8-11H,6-7,12-18H2	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	60	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Cairo University Curated by ChEMBL					Assay Description Antagonist activity at human Dopamine receptor D2 isoform long expressed in HEK293 cells assessed as change in quinpirole-induced intracellular calci...				Bioorg Med Chem 15: 5811-8 (2007) Article DOI: 10.1016/j.bmc.2007.06.002 BindingDB Entry DOI: 10.7270/Q27M07MZ
					More data for this Ligand-Target Pair
Cannabinoid receptor 2 (Homo sapiens (Human))	BDBM50202520 (CHEMBL3892329) Show SMILES CCOC(=O)c1cc(sc1NC(=O)c1cccc2ccccc12)-c1ccccc1 Show InChI InChI=1S/C24H19NO3S/c1-2-28-24(27)20-15-21(17-10-4-3-5-11-17)29-23(20)25-22(26)19-14-8-12-16-9-6-7-13-18(16)19/h3-15H,2H2,1H3,(H,25,26)	PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	60	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
German University in Cairo Curated by ChEMBL					Assay Description Displacement of [3H]-CP-55940 from human CB2 receptor expressed in HEK293 cell membranes after 90 mins by radioligand binding assay				Eur J Med Chem 122: 619-634 (2016) Article DOI: 10.1016/j.ejmech.2016.07.012 BindingDB Entry DOI: 10.7270/Q2057HX9
					More data for this Ligand-Target Pair
D(3) dopamine receptor (Homo sapiens (Human))	BDBM50216045 (2-(4-(4-(2-methoxyphenyl)-1-piperazinyl)butyl)-1,2...) Show SMILES O=C1N(CCCCN2CCN(CC2)c2ccccc2)S(=O)(=O)c2ccccc12 Show InChI InChI=1S/C21H25N3O3S/c25-21-19-10-4-5-11-20(19)28(26,27)24(21)13-7-6-12-22-14-16-23(17-15-22)18-8-2-1-3-9-18/h1-5,8-11H,6-7,12-17H2	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	66	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Cairo University Curated by ChEMBL					Assay Description Displacement of [3H]Spiperone from human Dopamine D3 receptor expressed in CHO cells				Bioorg Med Chem 15: 5811-8 (2007) Article DOI: 10.1016/j.bmc.2007.06.002 BindingDB Entry DOI: 10.7270/Q27M07MZ
					More data for this Ligand-Target Pair
D(2) dopamine receptor (Homo sapiens (Human))	BDBM50216053 (3-(4-(4-(3-a,a,a-trifluorotolyl)-1-piperazinyl)but...) Show SMILES FC(F)(F)c1cccc(c1)N1CCN(CCCCn2cnc3ccccc3c2=O)CC1 Show InChI InChI=1S/C23H25F3N4O/c24-23(25,26)18-6-5-7-19(16-18)29-14-12-28(13-15-29)10-3-4-11-30-17-27-21-9-2-1-8-20(21)22(30)31/h1-2,5-9,16-17H,3-4,10-15H2	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	73	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Cairo University Curated by ChEMBL					Assay Description Displacement of [3H]Spiperone from human Dopamine receptor D2 isoform long expressed in HEK293 cells				Bioorg Med Chem 15: 5811-8 (2007) Article DOI: 10.1016/j.bmc.2007.06.002 BindingDB Entry DOI: 10.7270/Q27M07MZ
					More data for this Ligand-Target Pair
D(1B) dopamine receptor (Homo sapiens (Human))	BDBM50216047 (2-(4-(4-phenyl-1-piperazinyl)butyl)-1-isoindolinon...) Show SMILES COc1ccccc1N1CCN(CCCCN2Cc3ccccc3C2=O)CC1 Show InChI InChI=1S/C23H29N3O2/c1-28-22-11-5-4-10-21(22)25-16-14-24(15-17-25)12-6-7-13-26-18-19-8-2-3-9-20(19)23(26)27/h2-5,8-11H,6-7,12-18H2,1H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	75.4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Cairo University Curated by ChEMBL					Assay Description Displacement of [3H]SCH 23390 from human Dopamine D5 receptor expressed in HEK293				Bioorg Med Chem 15: 5811-8 (2007) Article DOI: 10.1016/j.bmc.2007.06.002 BindingDB Entry DOI: 10.7270/Q27M07MZ
					More data for this Ligand-Target Pair
D(3) dopamine receptor (Homo sapiens (Human))	BDBM50216039 (1-(4-(4-(2-methoxyphenyl)-1-piperazinyl)butyl)-ind...) Show SMILES O=C1Cc2ccccc2N1CCCCN1CCN(CC1)c1ccccc1 Show InChI InChI=1S/C22H27N3O/c26-22-18-19-8-4-5-11-21(19)25(22)13-7-6-12-23-14-16-24(17-15-23)20-9-2-1-3-10-20/h1-5,8-11H,6-7,12-18H2	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	80	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Cairo University Curated by ChEMBL					Assay Description Displacement of [3H]Spiperone from human Dopamine D3 receptor expressed in CHO cells				Bioorg Med Chem 15: 5811-8 (2007) Article DOI: 10.1016/j.bmc.2007.06.002 BindingDB Entry DOI: 10.7270/Q27M07MZ
					More data for this Ligand-Target Pair
D(1B) dopamine receptor (Homo sapiens (Human))	BDBM50216048 (2-(4-(4-(2-methoxyphenyl)-1-piperazinyl)butyl)-1-i...) Show SMILES O=C1N(CCCCN2CCN(CC2)c2ccccc2)Cc2ccccc12 Show InChI InChI=1S/C22H27N3O/c26-22-21-11-5-4-8-19(21)18-25(22)13-7-6-12-23-14-16-24(17-15-23)20-9-2-1-3-10-20/h1-5,8-11H,6-7,12-18H2	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	80	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Cairo University Curated by ChEMBL					Assay Description Displacement of [3H]SCH 23390 from human Dopamine D5 receptor expressed in HEK293				Bioorg Med Chem 15: 5811-8 (2007) Article DOI: 10.1016/j.bmc.2007.06.002 BindingDB Entry DOI: 10.7270/Q27M07MZ
					More data for this Ligand-Target Pair
D(1B) dopamine receptor (Homo sapiens (Human))	BDBM50216044 (2-(4-(4-(3-a,a,a-trifluorotolyl)-1-piperazinyl)but...) Show SMILES FC(F)(F)c1cccc(c1)N1CCN(CCCCN2Cc3ccccc3C2=O)CC1 Show InChI InChI=1S/C23H26F3N3O/c24-23(25,26)19-7-5-8-20(16-19)28-14-12-27(13-15-28)10-3-4-11-29-17-18-6-1-2-9-21(18)22(29)30/h1-2,5-9,16H,3-4,10-15,17H2	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	80.8	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Cairo University Curated by ChEMBL					Assay Description Displacement of [3H]SCH 23390 from human Dopamine D5 receptor expressed in HEK293				Bioorg Med Chem 15: 5811-8 (2007) Article DOI: 10.1016/j.bmc.2007.06.002 BindingDB Entry DOI: 10.7270/Q27M07MZ
					More data for this Ligand-Target Pair
Cannabinoid receptor 1 (Homo sapiens (Human))	BDBM50516787 (CHEMBL4556046) Show SMILES O=C(NC12CC3CC(CC(C3)C1)C2)c1nc2ccccc2s1 |TLB:2:3:6:10.8.9,THB:8:7:4:10.9.11,8:9:6.7.12:4,11:3:6:10.8.9,11:9:6:3.12.4| Show InChI InChI=1S/C18H20N2OS/c21-16(17-19-14-3-1-2-4-15(14)22-17)20-18-8-11-5-12(9-18)7-13(6-11)10-18/h1-4,11-13H,5-10H2,(H,20,21)	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	82	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
German University in Cairo Curated by ChEMBL					Assay Description Displacement of [3H]CP55940 from recombinant human CB1R expressed in HEK293 cell membranes incubated for 90 mins by Cheng-Prusoff equation analysis				Eur J Med Chem 180: 154-170 (2019) Article DOI: 10.1016/j.ejmech.2019.07.002 BindingDB Entry DOI: 10.7270/Q2R214R1
					More data for this Ligand-Target Pair
Cannabinoid receptor 2 (Homo sapiens (Human))	BDBM50202543 (CHEMBL3963856) Show SMILES Cc1cc(C(=O)Nc2cccc3ccccc23)c(C)n1-c1ccccc1 Show InChI InChI=1S/C23H20N2O/c1-16-15-21(17(2)25(16)19-11-4-3-5-12-19)23(26)24-22-14-8-10-18-9-6-7-13-20(18)22/h3-15H,1-2H3,(H,24,26)	PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	84	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
German University in Cairo Curated by ChEMBL					Assay Description Displacement of [3H]-CP-55940 from human CB2 receptor expressed in HEK293 cell membranes after 90 mins by radioligand binding assay				Eur J Med Chem 122: 619-634 (2016) Article DOI: 10.1016/j.ejmech.2016.07.012 BindingDB Entry DOI: 10.7270/Q2057HX9
					More data for this Ligand-Target Pair
D(3) dopamine receptor (Homo sapiens (Human))	BDBM50216053 (3-(4-(4-(3-a,a,a-trifluorotolyl)-1-piperazinyl)but...) Show SMILES FC(F)(F)c1cccc(c1)N1CCN(CCCCn2cnc3ccccc3c2=O)CC1 Show InChI InChI=1S/C23H25F3N4O/c24-23(25,26)18-6-5-7-19(16-18)29-14-12-28(13-15-29)10-3-4-11-30-17-27-21-9-2-1-8-20(21)22(30)31/h1-2,5-9,16-17H,3-4,10-15H2	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	102	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Cairo University Curated by ChEMBL					Assay Description Displacement of [3H]Spiperone from human Dopamine D3 receptor expressed in CHO cells				Bioorg Med Chem 15: 5811-8 (2007) Article DOI: 10.1016/j.bmc.2007.06.002 BindingDB Entry DOI: 10.7270/Q27M07MZ
					More data for this Ligand-Target Pair
D(3) dopamine receptor (Homo sapiens (Human))	BDBM50216051 (2-(4-(4-(3-a,a,a-trifluorotolyl)-1-piperazinyl)but...) Show SMILES FC(F)(F)c1cccc(c1)N1CCN(CCCCN2C(=O)c3ccccc3S2(=O)=O)CC1 Show InChI InChI=1S/C22H24F3N3O3S/c23-22(24,25)17-6-5-7-18(16-17)27-14-12-26(13-15-27)10-3-4-11-28-21(29)19-8-1-2-9-20(19)32(28,30)31/h1-2,5-9,16H,3-4,10-15H2	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	107	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Cairo University Curated by ChEMBL					Assay Description Displacement of [3H]Spiperone from human Dopamine D3 receptor expressed in CHO cells				Bioorg Med Chem 15: 5811-8 (2007) Article DOI: 10.1016/j.bmc.2007.06.002 BindingDB Entry DOI: 10.7270/Q27M07MZ
					More data for this Ligand-Target Pair
Cannabinoid receptor 2 (Homo sapiens (Human))	BDBM50202522 (CHEMBL3910349) Show SMILES CCOC(=O)c1c(NC(=O)CCc2ccccc2)sc2CCCCc12 Show InChI InChI=1S/C20H23NO3S/c1-2-24-20(23)18-15-10-6-7-11-16(15)25-19(18)21-17(22)13-12-14-8-4-3-5-9-14/h3-5,8-9H,2,6-7,10-13H2,1H3,(H,21,22)	PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem	Article PubMed	112	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
German University in Cairo Curated by ChEMBL					Assay Description Displacement of [3H]-CP-55940 from human CB2 receptor expressed in HEK293 cell membranes after 90 mins by radioligand binding assay				Eur J Med Chem 122: 619-634 (2016) Article DOI: 10.1016/j.ejmech.2016.07.012 BindingDB Entry DOI: 10.7270/Q2057HX9
					More data for this Ligand-Target Pair
D(2) dopamine receptor (Homo sapiens (Human))	BDBM50216051 (2-(4-(4-(3-a,a,a-trifluorotolyl)-1-piperazinyl)but...) Show SMILES FC(F)(F)c1cccc(c1)N1CCN(CCCCN2C(=O)c3ccccc3S2(=O)=O)CC1 Show InChI InChI=1S/C22H24F3N3O3S/c23-22(24,25)17-6-5-7-18(16-17)27-14-12-26(13-15-27)10-3-4-11-28-21(29)19-8-1-2-9-20(19)32(28,30)31/h1-2,5-9,16H,3-4,10-15H2	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	113	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Cairo University Curated by ChEMBL					Assay Description Displacement of [3H]Spiperone from human Dopamine receptor D2 isoform long expressed in HEK293 cells				Bioorg Med Chem 15: 5811-8 (2007) Article DOI: 10.1016/j.bmc.2007.06.002 BindingDB Entry DOI: 10.7270/Q27M07MZ
					More data for this Ligand-Target Pair
Cannabinoid receptor 2 (Homo sapiens (Human))	BDBM50200170 (5-(4-chloro-3-methyl-phenyl)-1-(4-methyl-benzyl)-1...) Show SMILES Cc1ccc(Cn2nc(cc2-c2ccc(Cl)c(C)c2)C(=O)N[C@H]2[C@@]3(C)CC[C@H](C3)C2(C)C)cc1 |r| Show InChI InChI=1S/C29H34ClN3O/c1-18-6-8-20(9-7-18)17-33-25(21-10-11-23(30)19(2)14-21)15-24(32-33)26(34)31-27-28(3,4)22-12-13-29(27,5)16-22/h6-11,14-15,22,27H,12-13,16-17H2,1-5H3,(H,31,34)/t22-,27-,29+/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Similars	Article PubMed	117	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
German University in Cairo Curated by ChEMBL					Assay Description Displacement of [3H]CP55940 from recombinant human CB2R expressed in HEK293 cell membranes incubated for 90 mins by Cheng-Prusoff equation analysis				Eur J Med Chem 180: 154-170 (2019) Article DOI: 10.1016/j.ejmech.2019.07.002 BindingDB Entry DOI: 10.7270/Q2R214R1
					More data for this Ligand-Target Pair
Cannabinoid receptor 1 (Homo sapiens (Human))	BDBM50200170 (5-(4-chloro-3-methyl-phenyl)-1-(4-methyl-benzyl)-1...) Show SMILES Cc1ccc(Cn2nc(cc2-c2ccc(Cl)c(C)c2)C(=O)N[C@H]2[C@@]3(C)CC[C@H](C3)C2(C)C)cc1 |r| Show InChI InChI=1S/C29H34ClN3O/c1-18-6-8-20(9-7-18)17-33-25(21-10-11-23(30)19(2)14-21)15-24(32-33)26(34)31-27-28(3,4)22-12-13-29(27,5)16-22/h6-11,14-15,22,27H,12-13,16-17H2,1-5H3,(H,31,34)/t22-,27-,29+/m1/s1	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Similars	Article PubMed	117	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
German University in Cairo Curated by ChEMBL					Assay Description Displacement of [3H]-CP-55940 from human CB1 receptor expressed in HEK293 cell membranes after 90 mins by radioligand binding assay				Eur J Med Chem 122: 619-634 (2016) Article DOI: 10.1016/j.ejmech.2016.07.012 BindingDB Entry DOI: 10.7270/Q2057HX9
					More data for this Ligand-Target Pair
D(1B) dopamine receptor (Homo sapiens (Human))	BDBM50216047 (2-(4-(4-phenyl-1-piperazinyl)butyl)-1-isoindolinon...) Show SMILES COc1ccccc1N1CCN(CCCCN2Cc3ccccc3C2=O)CC1 Show InChI InChI=1S/C23H29N3O2/c1-28-22-11-5-4-10-21(22)25-16-14-24(15-17-25)12-6-7-13-26-18-19-8-2-3-9-20(19)23(26)27/h2-5,8-11H,6-7,12-18H2,1H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	137	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Cairo University Curated by ChEMBL					Assay Description Antagonist activity at human Dopamine D5 receptor in HEK293 cells assessed as change in SKF 38393-induced intracellular calcium response				Bioorg Med Chem 15: 5811-8 (2007) Article DOI: 10.1016/j.bmc.2007.06.002 BindingDB Entry DOI: 10.7270/Q27M07MZ
					More data for this Ligand-Target Pair
D(2) dopamine receptor (Homo sapiens (Human))	BDBM50216050 (3-(4-(4-(4-chlorophenyl)-1-piperazinyl)butyl)quina...) Show SMILES Clc1ccc(cc1)N1CCN(CCCCn2cnc3ccccc3c2=O)CC1 Show InChI InChI=1S/C22H25ClN4O/c23-18-7-9-19(10-8-18)26-15-13-25(14-16-26)11-3-4-12-27-17-24-21-6-2-1-5-20(21)22(27)28/h1-2,5-10,17H,3-4,11-16H2	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	140	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Cairo University Curated by ChEMBL					Assay Description Displacement of [3H]Spiperone from human Dopamine receptor D2 isoform long expressed in HEK293 cells				Bioorg Med Chem 15: 5811-8 (2007) Article DOI: 10.1016/j.bmc.2007.06.002 BindingDB Entry DOI: 10.7270/Q27M07MZ
					More data for this Ligand-Target Pair
D(2) dopamine receptor (Homo sapiens (Human))	BDBM50216039 (1-(4-(4-(2-methoxyphenyl)-1-piperazinyl)butyl)-ind...) Show SMILES O=C1Cc2ccccc2N1CCCCN1CCN(CC1)c1ccccc1 Show InChI InChI=1S/C22H27N3O/c26-22-18-19-8-4-5-11-21(19)25(22)13-7-6-12-23-14-16-24(17-15-23)20-9-2-1-3-10-20/h1-5,8-11H,6-7,12-18H2	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	153	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Cairo University Curated by ChEMBL					Assay Description Antagonist activity at human Dopamine receptor D2 isoform long expressed in HEK293 cells assessed as change in quinpirole-induced intracellular calci...				Bioorg Med Chem 15: 5811-8 (2007) Article DOI: 10.1016/j.bmc.2007.06.002 BindingDB Entry DOI: 10.7270/Q27M07MZ
					More data for this Ligand-Target Pair
D(2) dopamine receptor (Homo sapiens (Human))	BDBM50216039 (1-(4-(4-(2-methoxyphenyl)-1-piperazinyl)butyl)-ind...) Show SMILES O=C1Cc2ccccc2N1CCCCN1CCN(CC1)c1ccccc1 Show InChI InChI=1S/C22H27N3O/c26-22-18-19-8-4-5-11-21(19)25(22)13-7-6-12-23-14-16-24(17-15-23)20-9-2-1-3-10-20/h1-5,8-11H,6-7,12-18H2	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	162	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Cairo University Curated by ChEMBL					Assay Description Displacement of [3H]Spiperone from human Dopamine receptor D2 isoform long expressed in HEK293 cells				Bioorg Med Chem 15: 5811-8 (2007) Article DOI: 10.1016/j.bmc.2007.06.002 BindingDB Entry DOI: 10.7270/Q27M07MZ
					More data for this Ligand-Target Pair
D(2) dopamine receptor (Homo sapiens (Human))	BDBM50439461 (CHEMBL2420773) Show SMILES CCOc1ccccc1N1CCN(Cc2cccs2)CC1 Show InChI InChI=1S/C17H22N2OS/c1-2-20-17-8-4-3-7-16(17)19-11-9-18(10-12-19)14-15-6-5-13-21-15/h3-8,13H,2,9-12,14H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	162	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
German University in Cairo Curated by ChEMBL					Assay Description Displacement of [3H]spiperone from human dopamine D2 receptor				Bioorg Med Chem Lett 23: 5077-81 (2013) Article DOI: 10.1016/j.bmcl.2013.07.033 BindingDB Entry DOI: 10.7270/Q2RN399W
					More data for this Ligand-Target Pair
Cannabinoid receptor 2 (Homo sapiens (Human))	BDBM50202510 (CHEMBL3968899) Show SMILES Cc1cc(C(=O)NC2CCCCC2)c(C)n1-c1ccccc1 Show InChI InChI=1S/C19H24N2O/c1-14-13-18(19(22)20-16-9-5-3-6-10-16)15(2)21(14)17-11-7-4-8-12-17/h4,7-8,11-13,16H,3,5-6,9-10H2,1-2H3,(H,20,22)	PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	168	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
German University in Cairo Curated by ChEMBL					Assay Description Displacement of [3H]-CP-55940 from human CB2 receptor expressed in HEK293 cell membranes after 90 mins by radioligand binding assay				Eur J Med Chem 122: 619-634 (2016) Article DOI: 10.1016/j.ejmech.2016.07.012 BindingDB Entry DOI: 10.7270/Q2057HX9
					More data for this Ligand-Target Pair

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