Compile Data Set for Download or QSAR

Found 28 hits with Last Name = 'abbracchio' and Initial = 'mp'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
P2Y purinoceptor 12 (Homo sapiens (Human))	BDBM50318031 (CHEMBL1097279 | cangrelor) Show SMILES CSCCNc1nc(SCCC(F)(F)F)nc2n(cnc12)[C@@H]1O[C@H](COP([O-])(=O)OP([O-])(=O)C(Cl)(Cl)P([O-])([O-])=O)[C@@H](O)[C@H]1O |r| Show InChI InChI=1S/C17H25Cl2F3N5O12P3S2/c1-43-5-3-23-12-9-13(26-15(25-12)44-4-2-16(20,21)22)27(7-24-9)14-11(29)10(28)8(38-14)6-37-42(35,36)39-41(33,34)17(18,19)40(30,31)32/h7-8,10-11,14,28-29H,2-6H2,1H3,(H,33,34)(H,35,36)(H,23,25,26)(H2,30,31,32)/p-4/t8-,10-,11-,14-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	0.700	n/a	n/a	n/a	n/a	n/a	n/a
University of Pavia Curated by ChEMBL					Assay Description Antagonist activity at P2Y12 receptor by [35S]GTPgammaS binding assay				J Med Chem 53: 3489-501 (2010) Article DOI: 10.1021/jm901691y BindingDB Entry DOI: 10.7270/Q28C9WFW
					More data for this Ligand-Target Pair
Uracil nucleotide/cysteinyl leukotriene receptor (Homo sapiens (Human))	BDBM50318031 (CHEMBL1097279 | cangrelor) Show SMILES CSCCNc1nc(SCCC(F)(F)F)nc2n(cnc12)[C@@H]1O[C@H](COP([O-])(=O)OP([O-])(=O)C(Cl)(Cl)P([O-])([O-])=O)[C@@H](O)[C@H]1O |r| Show InChI InChI=1S/C17H25Cl2F3N5O12P3S2/c1-43-5-3-23-12-9-13(26-15(25-12)44-4-2-16(20,21)22)27(7-24-9)14-11(29)10(28)8(38-14)6-37-42(35,36)39-41(33,34)17(18,19)40(30,31)32/h7-8,10-11,14,28-29H,2-6H2,1H3,(H,33,34)(H,35,36)(H,23,25,26)(H2,30,31,32)/p-4/t8-,10-,11-,14-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	0.700	n/a	n/a	n/a	n/a	n/a	n/a
University of Pavia Curated by ChEMBL					Assay Description Antagonist activity at human GPR17 expressed in human 1321N1 cells assessed as inhibition of UDP-glucose-induced [35S]GTPgammaS binding after 30 mins...				J Med Chem 53: 3489-501 (2010) Article DOI: 10.1021/jm901691y BindingDB Entry DOI: 10.7270/Q28C9WFW
					More data for this Ligand-Target Pair
Uracil nucleotide/cysteinyl leukotriene receptor (Homo sapiens (Human))	BDBM50318030 (((2R,3S,4R,5R)-3,4-dihydroxy-5-(6-(methylamino)-9H...) Show SMILES CNc1ncnc2n(cnc12)[C@@H]1O[C@H](COP(O)(=O)OP(O)(=O)OP(O)(O)=O)[C@@H](O)[C@H]1O |r| Show InChI InChI=1S/C11H18N5O13P3/c1-12-9-6-10(14-3-13-9)16(4-15-6)11-8(18)7(17)5(27-11)2-26-31(22,23)29-32(24,25)28-30(19,20)21/h3-5,7-8,11,17-18H,2H2,1H3,(H,22,23)(H,24,25)(H,12,13,14)(H2,19,20,21)/t5-,7-,8-,11-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL KEGG PC cid PC sid PDB UniChem Similars	Article PubMed	n/a	n/a	112	n/a	n/a	n/a	n/a	n/a	n/a
University of Pavia Curated by ChEMBL					Assay Description Antagonist activity at human GPR17 expressed in human 1321N1 cells assessed as inhibition of UDP-glucose-induced [35S]GTPgammaS binding after 30 mins...				J Med Chem 53: 3489-501 (2010) Article DOI: 10.1021/jm901691y BindingDB Entry DOI: 10.7270/Q28C9WFW
					More data for this Ligand-Target Pair
P2Y purinoceptor 1 (Homo sapiens (Human))	BDBM50318029 (CHEMBL1096400 | diammonium (2R,3S,5R)-2-[(hydrogen...) Show SMILES CNc1ncnc2n(cnc12)[C@H]1C[C@H](OP(O)(O)=O)[C@@H](COP(O)(O)=O)O1 |r| Show InChI InChI=1S/C11H17N5O9P2/c1-12-10-9-11(14-4-13-10)16(5-15-9)8-2-6(25-27(20,21)22)7(24-8)3-23-26(17,18)19/h4-8H,2-3H2,1H3,(H,12,13,14)(H2,17,18,19)(H2,20,21,22)/t6-,7+,8+/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	508	n/a	n/a	n/a	n/a	n/a	n/a
University of Pavia Curated by ChEMBL					Assay Description Antagonist activity at P2Y1 receptor by [35S]GTPgammaS binding assay				J Med Chem 53: 3489-501 (2010) Article DOI: 10.1021/jm901691y BindingDB Entry DOI: 10.7270/Q28C9WFW
					More data for this Ligand-Target Pair
Uracil nucleotide/cysteinyl leukotriene receptor (Homo sapiens (Human))	BDBM50318029 (CHEMBL1096400 | diammonium (2R,3S,5R)-2-[(hydrogen...) Show SMILES CNc1ncnc2n(cnc12)[C@H]1C[C@H](OP(O)(O)=O)[C@@H](COP(O)(O)=O)O1 |r| Show InChI InChI=1S/C11H17N5O9P2/c1-12-10-9-11(14-4-13-10)16(5-15-9)8-2-6(25-27(20,21)22)7(24-8)3-23-26(17,18)19/h4-8H,2-3H2,1H3,(H,12,13,14)(H2,17,18,19)(H2,20,21,22)/t6-,7+,8+/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	508	n/a	n/a	n/a	n/a	n/a	n/a
University of Pavia Curated by ChEMBL					Assay Description Antagonist activity at human GPR17 expressed in human 1321N1 cells assessed as inhibition of UDP-glucose-induced [35S]GTPgammaS binding after 30 mins...				J Med Chem 53: 3489-501 (2010) Article DOI: 10.1021/jm901691y BindingDB Entry DOI: 10.7270/Q28C9WFW
					More data for this Ligand-Target Pair
Uracil nucleotide/cysteinyl leukotriene receptor (Homo sapiens (Human))	BDBM50318028 (CHEMBL1094760 | diammonium (2R,3S,5R)-5-(6-amino-2...) Show SMILES Nc1nc(Cl)nc2n(cnc12)[C@H]1C[C@H](OP(O)(O)=O)[C@@H](COP(O)(O)=O)O1 |r| Show InChI InChI=1S/C10H14ClN5O9P2/c11-10-14-8(12)7-9(15-10)16(3-13-7)6-1-4(25-27(20,21)22)5(24-6)2-23-26(17,18)19/h3-6H,1-2H2,(H2,12,14,15)(H2,17,18,19)(H2,20,21,22)/t4-,5+,6+/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	582	n/a	n/a	n/a	n/a	n/a	n/a
University of Pavia Curated by ChEMBL					Assay Description Antagonist activity at human GPR17 expressed in human 1321N1 cells assessed as inhibition of UDP-glucose-induced [35S]GTPgammaS binding after 30 mins...				J Med Chem 53: 3489-501 (2010) Article DOI: 10.1021/jm901691y BindingDB Entry DOI: 10.7270/Q28C9WFW
					More data for this Ligand-Target Pair
D(2) dopamine receptor (Rattus norvegicus (rat))	BDBM50002313 (2-Chloro-5-(2-{[2-(3-hydroxy-phenyl)-ethyl]-propyl...) Show SMILES CCCN(CCc1cccc(O)c1)CCc1ccc(Cl)c(O)c1 Show InChI InChI=1S/C19H24ClNO2/c1-2-10-21(11-8-15-4-3-5-17(22)13-15)12-9-16-6-7-18(20)19(23)14-16/h3-7,13-14,22-23H,2,8-12H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	730	n/a	n/a	n/a	n/a	n/a	n/a
University of Camerino Curated by ChEMBL					Assay Description Inhibitory activity against [3H]spiperone in Rat Striatal membrane				J Med Chem 35: 4408-14 (1992) BindingDB Entry DOI: 10.7270/Q2WH2QMC
					More data for this Ligand-Target Pair
D(2) dopamine receptor (Rattus norvegicus (rat))	BDBM50002310 (3-[2-(Phenethyl-propyl-amino)-ethyl]-phenol; hydro...) Show SMILES CCCN(CCc1ccccc1)CCc1cccc(O)c1 Show InChI InChI=1S/C19H25NO/c1-2-13-20(14-11-17-7-4-3-5-8-17)15-12-18-9-6-10-19(21)16-18/h3-10,16,21H,2,11-15H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	750	n/a	n/a	n/a	n/a	n/a	n/a
University of Camerino Curated by ChEMBL					Assay Description Inhibitory activity against [3H]spiperone in Rat Striatal membrane				J Med Chem 35: 4408-14 (1992) BindingDB Entry DOI: 10.7270/Q2WH2QMC
					More data for this Ligand-Target Pair
D(2) dopamine receptor (Rattus norvegicus (rat))	BDBM50002314 (2-Chloro-5-(2-{[3-(4-hydroxy-phenyl)-propyl]-propy...) Show SMILES CCCN(CCCc1ccc(O)cc1)CCc1ccc(Cl)c(O)c1 Show InChI InChI=1S/C20H26ClNO2/c1-2-12-22(13-3-4-16-5-8-18(23)9-6-16)14-11-17-7-10-19(21)20(24)15-17/h5-10,15,23-24H,2-4,11-14H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	850	n/a	n/a	n/a	n/a	n/a	n/a
University of Camerino Curated by ChEMBL					Assay Description Inhibitory activity against [3H]spiperone in Rat Striatal membrane				J Med Chem 35: 4408-14 (1992) BindingDB Entry DOI: 10.7270/Q2WH2QMC
					More data for this Ligand-Target Pair
D(2) dopamine receptor (Rattus norvegicus (rat))	BDBM50002309 (2-Chloro-5-(2-{[2-(4-hydroxy-phenyl)-ethyl]-propyl...) Show SMILES CCCN(CCc1ccc(O)cc1)CCc1ccc(Cl)c(O)c1 Show InChI InChI=1S/C19H24ClNO2/c1-2-11-21(12-9-15-3-6-17(22)7-4-15)13-10-16-5-8-18(20)19(23)14-16/h3-8,14,22-23H,2,9-13H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	900	n/a	n/a	n/a	n/a	n/a	n/a
University of Camerino Curated by ChEMBL					Assay Description Inhibitory activity against [3H]spiperone in Rat Striatal membrane				J Med Chem 35: 4408-14 (1992) BindingDB Entry DOI: 10.7270/Q2WH2QMC
					More data for this Ligand-Target Pair
D(2) dopamine receptor (Rattus norvegicus (rat))	BDBM50002311 (2-Chloro-5-[2-(phenethyl-propyl-amino)-ethyl]-phen...) Show SMILES CCCN(CCc1ccccc1)CCc1ccc(Cl)c(O)c1 Show InChI InChI=1S/C19H24ClNO/c1-2-12-21(13-10-16-6-4-3-5-7-16)14-11-17-8-9-18(20)19(22)15-17/h3-9,15,22H,2,10-14H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	1.39E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Camerino Curated by ChEMBL					Assay Description Inhibitory activity against [3H]spiperone in Rat Striatal membrane				J Med Chem 35: 4408-14 (1992) BindingDB Entry DOI: 10.7270/Q2WH2QMC
					More data for this Ligand-Target Pair
D(2) dopamine receptor (Rattus norvegicus (rat))	BDBM55121 (3-HYDROXYTYRAMINE HYDROCHLORIDE | 4-(2-aminoethyl)...) Show SMILES NCCc1ccc(O)c(O)c1 Show InChI InChI=1S/C8H11NO2/c9-4-3-6-1-2-7(10)8(11)5-6/h1-2,5,10-11H,3-4,9H2	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase DrugBank KEGG PC cid PC sid PDB UniChem Similars	PubMed	n/a	n/a	3.50E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Camerino Curated by ChEMBL					Assay Description Inhibitory activity against [3H]spiperone in Rat Striatal membrane				J Med Chem 35: 4408-14 (1992) BindingDB Entry DOI: 10.7270/Q2WH2QMC
					More data for this Ligand-Target Pair
D(1A) dopamine receptor (RAT)	BDBM55121 (3-HYDROXYTYRAMINE HYDROCHLORIDE | 4-(2-aminoethyl)...) Show SMILES NCCc1ccc(O)c(O)c1 Show InChI InChI=1S/C8H11NO2/c9-4-3-6-1-2-7(10)8(11)5-6/h1-2,5,10-11H,3-4,9H2	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase DrugBank KEGG PC cid PC sid PDB UniChem Similars	PDB PubMed	n/a	n/a	3.70E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Camerino Curated by ChEMBL					Assay Description Inhibitory activity against [3H]-SCH- 23390 in Rat Striatal membrane				J Med Chem 35: 4408-14 (1992) BindingDB Entry DOI: 10.7270/Q2WH2QMC
					More data for this Ligand-Target Pair				3D Structure (crystal)
D(1A) dopamine receptor (RAT)	BDBM50002313 (2-Chloro-5-(2-{[2-(3-hydroxy-phenyl)-ethyl]-propyl...) Show SMILES CCCN(CCc1cccc(O)c1)CCc1ccc(Cl)c(O)c1 Show InChI InChI=1S/C19H24ClNO2/c1-2-10-21(11-8-15-4-3-5-17(22)13-15)12-9-16-6-7-18(20)19(23)14-16/h3-7,13-14,22-23H,2,8-12H2,1H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	1.12E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Camerino Curated by ChEMBL					Assay Description Inhibitory activity against [3H]-SCH- 23390 in Rat Striatal membrane				J Med Chem 35: 4408-14 (1992) BindingDB Entry DOI: 10.7270/Q2WH2QMC
					More data for this Ligand-Target Pair
D(2) dopamine receptor (Rattus norvegicus (rat))	BDBM50002312 (2-Chloro-5-(2-dipropylamino-ethyl)-phenol; hydrobr...) Show SMILES CCCN(CCC)CCc1ccc(Cl)c(O)c1 Show InChI InChI=1S/C14H22ClNO/c1-3-8-16(9-4-2)10-7-12-5-6-13(15)14(17)11-12/h5-6,11,17H,3-4,7-10H2,1-2H3	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	1.29E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Camerino Curated by ChEMBL					Assay Description Inhibitory activity against [3H]spiperone in Rat Striatal membrane				J Med Chem 35: 4408-14 (1992) BindingDB Entry DOI: 10.7270/Q2WH2QMC
					More data for this Ligand-Target Pair
D(1A) dopamine receptor (RAT)	BDBM50002314 (2-Chloro-5-(2-{[3-(4-hydroxy-phenyl)-propyl]-propy...) Show SMILES CCCN(CCCc1ccc(O)cc1)CCc1ccc(Cl)c(O)c1 Show InChI InChI=1S/C20H26ClNO2/c1-2-12-22(13-3-4-16-5-8-18(23)9-6-16)14-11-17-7-10-19(21)20(24)15-17/h5-10,15,23-24H,2-4,11-14H2,1H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	1.69E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Camerino Curated by ChEMBL					Assay Description Inhibitory activity against [3H]-SCH- 23390 in Rat Striatal membrane				J Med Chem 35: 4408-14 (1992) BindingDB Entry DOI: 10.7270/Q2WH2QMC
					More data for this Ligand-Target Pair
D(1A) dopamine receptor (RAT)	BDBM50002309 (2-Chloro-5-(2-{[2-(4-hydroxy-phenyl)-ethyl]-propyl...) Show SMILES CCCN(CCc1ccc(O)cc1)CCc1ccc(Cl)c(O)c1 Show InChI InChI=1S/C19H24ClNO2/c1-2-11-21(12-9-15-3-6-17(22)7-4-15)13-10-16-5-8-18(20)19(23)14-16/h3-8,14,22-23H,2,9-13H2,1H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	1.81E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Camerino Curated by ChEMBL					Assay Description Inhibitory activity against [3H]-SCH- 23390 in Rat Striatal membrane				J Med Chem 35: 4408-14 (1992) BindingDB Entry DOI: 10.7270/Q2WH2QMC
					More data for this Ligand-Target Pair
D(1A) dopamine receptor (RAT)	BDBM50002311 (2-Chloro-5-[2-(phenethyl-propyl-amino)-ethyl]-phen...) Show SMILES CCCN(CCc1ccccc1)CCc1ccc(Cl)c(O)c1 Show InChI InChI=1S/C19H24ClNO/c1-2-12-21(13-10-16-6-4-3-5-7-16)14-11-17-8-9-18(20)19(22)15-17/h3-9,15,22H,2,10-14H2,1H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	2.44E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Camerino Curated by ChEMBL					Assay Description Inhibitory activity against [3H]-SCH- 23390 in Rat Striatal membrane				J Med Chem 35: 4408-14 (1992) BindingDB Entry DOI: 10.7270/Q2WH2QMC
					More data for this Ligand-Target Pair
D(1A) dopamine receptor (RAT)	BDBM50002315 (5-(2-Amino-ethyl)-2-chloro-phenol; hydrobromide | ...) Show SMILES NCCc1ccc(Cl)c(O)c1 Show InChI InChI=1S/C8H10ClNO/c9-7-2-1-6(3-4-10)5-8(7)11/h1-2,5,11H,3-4,10H2	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	PubMed	n/a	n/a	2.53E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Camerino Curated by ChEMBL					Assay Description Inhibitory activity against [3H]-SCH- 23390 in Rat Striatal membrane				J Med Chem 35: 4408-14 (1992) BindingDB Entry DOI: 10.7270/Q2WH2QMC
					More data for this Ligand-Target Pair
D(2) dopamine receptor (Rattus norvegicus (rat))	BDBM50002315 (5-(2-Amino-ethyl)-2-chloro-phenol; hydrobromide | ...) Show SMILES NCCc1ccc(Cl)c(O)c1 Show InChI InChI=1S/C8H10ClNO/c9-7-2-1-6(3-4-10)5-8(7)11/h1-2,5,11H,3-4,10H2	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	PubMed	n/a	n/a	2.63E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Camerino Curated by ChEMBL					Assay Description Inhibitory activity against [3H]spiperone in Rat Striatal membrane				J Med Chem 35: 4408-14 (1992) BindingDB Entry DOI: 10.7270/Q2WH2QMC
					More data for this Ligand-Target Pair
D(1A) dopamine receptor (RAT)	BDBM50002312 (2-Chloro-5-(2-dipropylamino-ethyl)-phenol; hydrobr...) Show SMILES CCCN(CCC)CCc1ccc(Cl)c(O)c1 Show InChI InChI=1S/C14H22ClNO/c1-3-8-16(9-4-2)10-7-12-5-6-13(15)14(17)11-12/h5-6,11,17H,3-4,7-10H2,1-2H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	5.07E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Camerino Curated by ChEMBL					Assay Description Inhibitory activity against [3H]-SCH- 23390 in Rat Striatal membrane				J Med Chem 35: 4408-14 (1992) BindingDB Entry DOI: 10.7270/Q2WH2QMC
					More data for this Ligand-Target Pair
D(1A) dopamine receptor (RAT)	BDBM50002310 (3-[2-(Phenethyl-propyl-amino)-ethyl]-phenol; hydro...) Show SMILES CCCN(CCc1ccccc1)CCc1cccc(O)c1 Show InChI InChI=1S/C19H25NO/c1-2-13-20(14-11-17-7-4-3-5-8-17)15-12-18-9-6-10-19(21)16-18/h3-10,16,21H,2,11-15H2,1H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	9.28E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Camerino Curated by ChEMBL					Assay Description Inhibitory activity against [3H]-SCH- 23390 in Rat Striatal membrane				J Med Chem 35: 4408-14 (1992) BindingDB Entry DOI: 10.7270/Q2WH2QMC
					More data for this Ligand-Target Pair
Uracil nucleotide/cysteinyl leukotriene receptor (Homo sapiens (Human))	BDBM50318024 (((2R,3S,4R,5R)-5-(2-chloro-6-(methylamino)-9H-puri...) Show SMILES CNc1nc(Cl)nc2n(cnc12)[C@@H]1O[C@H](COP(O)(=O)OP(O)(=O)OP(O)(O)=O)[C@@H](O)[C@H]1O |r| Show InChI InChI=1S/C11H17ClN5O13P3/c1-13-8-5-9(16-11(12)15-8)17(3-14-5)10-7(19)6(18)4(28-10)2-27-32(23,24)30-33(25,26)29-31(20,21)22/h3-4,6-7,10,18-19H,2H2,1H3,(H,23,24)(H,25,26)(H,13,15,16)(H2,20,21,22)/t4-,6-,7-,10-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL KEGG PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	11	n/a	n/a	n/a	n/a
University of Pavia Curated by ChEMBL					Assay Description Agonist activity at human GPR17 expressed in human 1321N1 cells assessed as induction of [35S]GTPgammaS binding after 30 mins by rapid filtration ass...				J Med Chem 53: 3489-501 (2010) Article DOI: 10.1021/jm901691y BindingDB Entry DOI: 10.7270/Q28C9WFW
					More data for this Ligand-Target Pair
Uracil nucleotide/cysteinyl leukotriene receptor (Homo sapiens (Human))	BDBM50318022 (CHEMBL1096401 | uridine diphosphate trisodium salt) Show SMILES O[C@H]1[C@@H](O)[C@@H](O[C@@H]1COP([O-])(=O)OP([O-])([O-])=O)n1ccc(=O)[nH]c1=O |r| Show InChI InChI=1S/C9H14N2O12P2/c12-5-1-2-11(9(15)10-5)8-7(14)6(13)4(22-8)3-21-25(19,20)23-24(16,17)18/h1-2,4,6-8,13-14H,3H2,(H,19,20)(H,10,12,15)(H2,16,17,18)/p-3/t4-,6-,7-,8-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE KEGG PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	1.14E+3	n/a	n/a	n/a	n/a
University of Pavia Curated by ChEMBL					Assay Description Agonist activity at human GPR17 expressed in human 1321N1 cells assessed as induction of [35S]GTPgammaS binding after 30 mins by rapid filtration ass...				J Med Chem 53: 3489-501 (2010) Article DOI: 10.1021/jm901691y BindingDB Entry DOI: 10.7270/Q28C9WFW
					More data for this Ligand-Target Pair
Uracil nucleotide/cysteinyl leukotriene receptor (Homo sapiens (Human))	BDBM50318025 (((2R,3S,4R,5R)-5-(6-chloro-4-(methylamino)-1H-imid...) Show SMILES CNc1nc(Cl)cc2n(cnc12)[C@@H]1O[C@H](COP(O)(=O)OP(O)(=O)OP(O)(O)=O)[C@@H](O)[C@H]1O |r| Show InChI InChI=1S/C12H18ClN4O13P3/c1-14-11-8-5(2-7(13)16-11)17(4-15-8)12-10(19)9(18)6(28-12)3-27-32(23,24)30-33(25,26)29-31(20,21)22/h2,4,6,9-10,12,18-19H,3H2,1H3,(H,14,16)(H,23,24)(H,25,26)(H2,20,21,22)/t6-,9-,10-,12-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL KEGG PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	1.70	n/a	n/a	n/a	n/a
University of Pavia Curated by ChEMBL					Assay Description Agonist activity at human GPR17 expressed in human 1321N1 cells assessed as induction of [35S]GTPgammaS binding after 30 mins by rapid filtration ass...				J Med Chem 53: 3489-501 (2010) Article DOI: 10.1021/jm901691y BindingDB Entry DOI: 10.7270/Q28C9WFW
					More data for this Ligand-Target Pair
Uracil nucleotide/cysteinyl leukotriene receptor (Homo sapiens (Human))	BDBM50318026 (((2R,3S,4R,5R)-5-(6-(cyclopentylamino)-9H-purin-9-...) Show SMILES O[C@@H]1[C@@H](COP(O)(=O)OP(O)(=O)OP(O)(O)=O)O[C@H]([C@@H]1O)n1cnc2c(NC3CCCC3)ncnc12 |r| Show InChI InChI=1S/C15H24N5O13P3/c21-11-9(5-30-35(26,27)33-36(28,29)32-34(23,24)25)31-15(12(11)22)20-7-18-10-13(16-6-17-14(10)20)19-8-3-1-2-4-8/h6-9,11-12,15,21-22H,1-5H2,(H,26,27)(H,28,29)(H,16,17,19)(H2,23,24,25)/t9-,11-,12-,15-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL KEGG PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	1.40	n/a	n/a	n/a	n/a
University of Pavia Curated by ChEMBL					Assay Description Agonist activity at human GPR17 expressed in human 1321N1 cells assessed as induction of [35S]GTPgammaS binding after 30 mins by rapid filtration ass...				J Med Chem 53: 3489-501 (2010) Article DOI: 10.1021/jm901691y BindingDB Entry DOI: 10.7270/Q28C9WFW
					More data for this Ligand-Target Pair
Uracil nucleotide/cysteinyl leukotriene receptor (Homo sapiens (Human))	BDBM50318027 (((2R,3S,4R,5R)-5-(6-amino-2-(phenylethynyl)-9H-pur...) Show SMILES Nc1nc(nc2n(cnc12)[C@@H]1O[C@H](COP(O)(=O)OP(O)(=O)OP(O)(O)=O)[C@@H](O)[C@H]1O)C#Cc1ccccc1 |r| Show InChI InChI=1S/C18H20N5O13P3/c19-16-13-17(22-12(21-16)7-6-10-4-2-1-3-5-10)23(9-20-13)18-15(25)14(24)11(34-18)8-33-38(29,30)36-39(31,32)35-37(26,27)28/h1-5,9,11,14-15,18,24-25H,8H2,(H,29,30)(H,31,32)(H2,19,21,22)(H2,26,27,28)/t11-,14-,15-,18-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL KEGG PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	0.0360	n/a	n/a	n/a	n/a
University of Pavia Curated by ChEMBL					Assay Description Agonist activity at human GPR17 expressed in human 1321N1 cells assessed as induction of [35S]GTPgammaS binding after 30 mins by rapid filtration ass...				J Med Chem 53: 3489-501 (2010) Article DOI: 10.1021/jm901691y BindingDB Entry DOI: 10.7270/Q28C9WFW
					More data for this Ligand-Target Pair
Uracil nucleotide/cysteinyl leukotriene receptor (Homo sapiens (Human))	BDBM50306710 (((2R,3S,4R,5R)-3,4-dihydroxy-5-(5-iodo-2,4-dioxo-3...) Show SMILES O[C@H]1[C@@H](O)[C@@H](O[C@@H]1COP(O)(=O)OP(O)(O)=O)n1cc(I)c(=O)[nH]c1=O |r| Show InChI InChI=1S/C9H13IN2O12P2/c10-3-1-12(9(16)11-7(3)15)8-6(14)5(13)4(23-8)2-22-26(20,21)24-25(17,18)19/h1,4-6,8,13-14H,2H2,(H,20,21)(H,11,15,16)(H2,17,18,19)/t4-,5-,6-,8-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL KEGG PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	945	n/a	n/a	n/a	n/a
University of Pavia Curated by ChEMBL					Assay Description Agonist activity at human GPR17 expressed in human 1321N1 cells assessed as induction of [35S]GTPgammaS binding after 30 mins by rapid filtration ass...				J Med Chem 53: 3489-501 (2010) Article DOI: 10.1021/jm901691y BindingDB Entry DOI: 10.7270/Q28C9WFW
					More data for this Ligand-Target Pair