Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Urease subunit alpha (Helicobacter pylori) | BDBM221061 (7-(4-Acetylpiperazin-1-yl)-1-cyclopropyl-6-fluoro-...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 1.22E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Minia University | Assay Description The assay mixture, containing 50 μl (2 mg/ml) of enzyme and 100 μl of different concentration of the tested agents, was added to 850 μ... | Bioorg Chem 70: 1-11 (2017) Article DOI: 10.1016/j.bioorg.2016.11.002 BindingDB Entry DOI: 10.7270/Q2PZ57NS | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Urease subunit alpha (Helicobacter pylori) | BDBM221056 (7-(4-Acetylpiperazin-1-yl)-1-cyclopropyl-6-fluoro-...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 1.29E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Minia University | Assay Description The assay mixture, containing 50 μl (2 mg/ml) of enzyme and 100 μl of different concentration of the tested agents, was added to 850 μ... | Bioorg Chem 70: 1-11 (2017) Article DOI: 10.1016/j.bioorg.2016.11.002 BindingDB Entry DOI: 10.7270/Q2PZ57NS | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Urease subunit alpha (Helicobacter pylori) | BDBM221063 (7-(4-(3,4,5-Trimethoxy piperazin-1-yl))-1-cyclopro...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 2.08E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Minia University | Assay Description The assay mixture, containing 50 μl (2 mg/ml) of enzyme and 100 μl of different concentration of the tested agents, was added to 850 μ... | Bioorg Chem 70: 1-11 (2017) Article DOI: 10.1016/j.bioorg.2016.11.002 BindingDB Entry DOI: 10.7270/Q2PZ57NS | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Urease subunit alpha (Helicobacter pylori) | BDBM221066 ((S)-9-Fluoro-3,7-dihydro-N-hydroxy-3-methyl-10-(4-...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 2.20E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Minia University | Assay Description The assay mixture, containing 50 μl (2 mg/ml) of enzyme and 100 μl of different concentration of the tested agents, was added to 850 μ... | Bioorg Chem 70: 1-11 (2017) Article DOI: 10.1016/j.bioorg.2016.11.002 BindingDB Entry DOI: 10.7270/Q2PZ57NS | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Urease subunit alpha (Helicobacter pylori) | BDBM221051 (7-(4-Acetylpiperazin-1-yl)-1-cyclopropyl-6-fluoro-...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 2.22E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Minia University | Assay Description The assay mixture, containing 50 μl (2 mg/ml) of enzyme and 100 μl of different concentration of the tested agents, was added to 850 μ... | Bioorg Chem 70: 1-11 (2017) Article DOI: 10.1016/j.bioorg.2016.11.002 BindingDB Entry DOI: 10.7270/Q2PZ57NS | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Urease subunit alpha (Helicobacter pylori) | BDBM221050 (N-acetyl ciprofloxacin) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | Purchase MCE PC cid PC sid UniChem | Article PubMed | n/a | n/a | 2.26E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Minia University | Assay Description The assay mixture, containing 50 μl (2 mg/ml) of enzyme and 100 μl of different concentration of the tested agents, was added to 850 μ... | Bioorg Chem 70: 1-11 (2017) Article DOI: 10.1016/j.bioorg.2016.11.002 BindingDB Entry DOI: 10.7270/Q2PZ57NS | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Urease subunit alpha (Helicobacter pylori) | BDBM221067 ((S)-9-Fluoro-3,7-dihydro-N,3-dimethyl-10-(4-methyl...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 2.89E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Minia University | Assay Description The assay mixture, containing 50 μl (2 mg/ml) of enzyme and 100 μl of different concentration of the tested agents, was added to 850 μ... | Bioorg Chem 70: 1-11 (2017) Article DOI: 10.1016/j.bioorg.2016.11.002 BindingDB Entry DOI: 10.7270/Q2PZ57NS | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Urease subunit alpha (Helicobacter pylori) | BDBM221058 (7-(4-(3,4,5-Trimetoxybenzoylpiperazin-1-yl))-1-cyc...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 2.92E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Minia University | Assay Description The assay mixture, containing 50 μl (2 mg/ml) of enzyme and 100 μl of different concentration of the tested agents, was added to 850 μ... | Bioorg Chem 70: 1-11 (2017) Article DOI: 10.1016/j.bioorg.2016.11.002 BindingDB Entry DOI: 10.7270/Q2PZ57NS | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Urease subunit alpha (Helicobacter pylori) | BDBM221053 (7-(4-(3,4,5-Trimethoxybenzoylpiperazin-1-yl)-1-cyc...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 7.17E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Minia University | Assay Description The assay mixture, containing 50 μl (2 mg/ml) of enzyme and 100 μl of different concentration of the tested agents, was added to 850 μ... | Bioorg Chem 70: 1-11 (2017) Article DOI: 10.1016/j.bioorg.2016.11.002 BindingDB Entry DOI: 10.7270/Q2PZ57NS | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Urease subunit alpha (Helicobacter pylori) | BDBM221052 (7-(4-Benzoylpiperazin-1-yl)-1-cyclopropyl-6-fluoro...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 1.89E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Minia University | Assay Description The assay mixture, containing 50 μl (2 mg/ml) of enzyme and 100 μl of different concentration of the tested agents, was added to 850 μ... | Bioorg Chem 70: 1-11 (2017) Article DOI: 10.1016/j.bioorg.2016.11.002 BindingDB Entry DOI: 10.7270/Q2PZ57NS | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Urease subunit alpha (Helicobacter pylori) | BDBM221054 (7-(4-((4-((E)-3-(Phenylacryloyl)phenylcarbamoyl)me...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 1.93E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Minia University | Assay Description The assay mixture, containing 50 μl (2 mg/ml) of enzyme and 100 μl of different concentration of the tested agents, was added to 850 μ... | Bioorg Chem 70: 1-11 (2017) Article DOI: 10.1016/j.bioorg.2016.11.002 BindingDB Entry DOI: 10.7270/Q2PZ57NS | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Urease subunit alpha (Helicobacter pylori) | BDBM50099857 (ACETOHYDROXAMIC ACID (AHA) | AHA | Acethydroxamsae...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | Purchase DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents | PDB Article PubMed | n/a | n/a | 1.20E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Minia University | Assay Description The assay mixture, containing 50 μl (2 mg/ml) of enzyme and 100 μl of different concentration of the tested agents, was added to 850 μ... | Bioorg Chem 70: 1-11 (2017) Article DOI: 10.1016/j.bioorg.2016.11.002 BindingDB Entry DOI: 10.7270/Q2PZ57NS | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (crystal) | ||||||||||||
Urease subunit alpha (Helicobacter pylori) | BDBM221062 (7-(4-Benzoylpiperazin-1-yl)-1-cyclopropyl-6-fluoro...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 2.50E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Minia University | Assay Description The assay mixture, containing 50 μl (2 mg/ml) of enzyme and 100 μl of different concentration of the tested agents, was added to 850 μ... | Bioorg Chem 70: 1-11 (2017) Article DOI: 10.1016/j.bioorg.2016.11.002 BindingDB Entry DOI: 10.7270/Q2PZ57NS | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Urease subunit alpha (Helicobacter pylori) | BDBM221060 (7-(4-((4-((E)-3-(3,4,5-Trimetoxyphenylacryloyl)phe...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 6.31E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Minia University | Assay Description The assay mixture, containing 50 μl (2 mg/ml) of enzyme and 100 μl of different concentration of the tested agents, was added to 850 μ... | Bioorg Chem 70: 1-11 (2017) Article DOI: 10.1016/j.bioorg.2016.11.002 BindingDB Entry DOI: 10.7270/Q2PZ57NS | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Urease subunit alpha (Helicobacter pylori) | BDBM221068 ((S)-9-Fluoro-3,7-dihydro-3-methyl-10-(4-methylpipe...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 7.72E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Minia University | Assay Description The assay mixture, containing 50 μl (2 mg/ml) of enzyme and 100 μl of different concentration of the tested agents, was added to 850 μ... | Bioorg Chem 70: 1-11 (2017) Article DOI: 10.1016/j.bioorg.2016.11.002 BindingDB Entry DOI: 10.7270/Q2PZ57NS | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Urease subunit alpha (Helicobacter pylori) | BDBM221064 (7-(4-((4-((E)-3-(Phenylacryloyl)phenylcarbamoyl)me...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 8.12E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Minia University | Assay Description The assay mixture, containing 50 μl (2 mg/ml) of enzyme and 100 μl of different concentration of the tested agents, was added to 850 μ... | Bioorg Chem 70: 1-11 (2017) Article DOI: 10.1016/j.bioorg.2016.11.002 BindingDB Entry DOI: 10.7270/Q2PZ57NS | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Urease subunit alpha (Helicobacter pylori) | BDBM221065 (7-(4-((4-((E)-3-(3,4,5-Trimetoxyphenylacryloyl)phe...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 9.12E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Minia University | Assay Description The assay mixture, containing 50 μl (2 mg/ml) of enzyme and 100 μl of different concentration of the tested agents, was added to 850 μ... | Bioorg Chem 70: 1-11 (2017) Article DOI: 10.1016/j.bioorg.2016.11.002 BindingDB Entry DOI: 10.7270/Q2PZ57NS | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Urease subunit alpha (Helicobacter pylori) | BDBM221055 (7-(4-((4-((E)-3-(3,4,5-Trimetoxyphenylacryloyl)phe...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 9.49E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Minia University | Assay Description The assay mixture, containing 50 μl (2 mg/ml) of enzyme and 100 μl of different concentration of the tested agents, was added to 850 μ... | Bioorg Chem 70: 1-11 (2017) Article DOI: 10.1016/j.bioorg.2016.11.002 BindingDB Entry DOI: 10.7270/Q2PZ57NS | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Urease subunit alpha (Helicobacter pylori) | BDBM221059 (7-(4-((4-((E)-3-(Phenylacryloyl)phenylcarbamoyl)me...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 2.41E+6 | n/a | n/a | n/a | n/a | n/a | n/a |
Minia University | Assay Description The assay mixture, containing 50 μl (2 mg/ml) of enzyme and 100 μl of different concentration of the tested agents, was added to 850 μ... | Bioorg Chem 70: 1-11 (2017) Article DOI: 10.1016/j.bioorg.2016.11.002 BindingDB Entry DOI: 10.7270/Q2PZ57NS | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Urease subunit alpha (Helicobacter pylori) | BDBM221057 (7-(4-Benzoylpiperazin-1-yl)-1-cyclopropyl-6-fluoro...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 2.50E+6 | n/a | n/a | n/a | n/a | n/a | n/a |
Minia University | Assay Description The assay mixture, containing 50 μl (2 mg/ml) of enzyme and 100 μl of different concentration of the tested agents, was added to 850 μ... | Bioorg Chem 70: 1-11 (2017) Article DOI: 10.1016/j.bioorg.2016.11.002 BindingDB Entry DOI: 10.7270/Q2PZ57NS | |||||||||||
More data for this Ligand-Target Pair |