Found 30 hits with Last Name = 'abdi' and Initial = 'mh' Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
P2X purinoceptor 7
(Homo sapiens (Human)) | BDBM50416599
(CHEMBL1222821)Show SMILES CCN1[C@@H](CCC1=O)C(=O)NCc1cccc(c1Cl)C(F)(F)F |r| Show InChI InChI=1S/C15H16ClF3N2O2/c1-2-21-11(6-7-12(21)22)14(23)20-8-9-4-3-5-10(13(9)16)15(17,18)19/h3-5,11H,2,6-8H2,1H3,(H,20,23)/t11-/m0/s1 | PDB
KEGG
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 1.58 | n/a | n/a | n/a | n/a | n/a | n/a |
GlaxoSmithKline
Curated by ChEMBL
| Assay Description Inhibition of human P2X7 receptor by ethidium bromide release assay |
Bioorg Med Chem Lett 20: 5080-4 (2010)
Article DOI: 10.1016/j.bmcl.2010.07.033 BindingDB Entry DOI: 10.7270/Q289173T |
More data for this Ligand-Target Pair | |
P2X purinoceptor 7
(Homo sapiens (Human)) | BDBM50416603
(CHEMBL1222883)Show SMILES CN1[C@@H](CCC1=O)C(=O)NCc1cccc(c1Cl)C(F)(F)F |r| Show InChI InChI=1S/C14H14ClF3N2O2/c1-20-10(5-6-11(20)21)13(22)19-7-8-3-2-4-9(12(8)15)14(16,17)18/h2-4,10H,5-7H2,1H3,(H,19,22)/t10-/m0/s1 | PDB
KEGG
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| Purchase
CHEMBL MCE PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 3.16 | n/a | n/a | n/a | n/a | n/a | n/a |
GlaxoSmithKline
Curated by ChEMBL
| Assay Description Inhibition of human P2X7 receptor by ethidium bromide release assay |
Bioorg Med Chem Lett 20: 5080-4 (2010)
Article DOI: 10.1016/j.bmcl.2010.07.033 BindingDB Entry DOI: 10.7270/Q289173T |
More data for this Ligand-Target Pair | |
P2X purinoceptor 7
(Homo sapiens (Human)) | BDBM50416598
(CHEMBL1222820)Show SMILES CCN1[C@@H](CCC1=O)C(=O)NCc1ccc(Cl)cc1Cl |r| Show InChI InChI=1S/C14H16Cl2N2O2/c1-2-18-12(5-6-13(18)19)14(20)17-8-9-3-4-10(15)7-11(9)16/h3-4,7,12H,2,5-6,8H2,1H3,(H,17,20)/t12-/m0/s1 | PDB
KEGG
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 6.31 | n/a | n/a | n/a | n/a | n/a | n/a |
GlaxoSmithKline
Curated by ChEMBL
| Assay Description Inhibition of human P2X7 receptor by ethidium bromide release assay |
Bioorg Med Chem Lett 20: 5080-4 (2010)
Article DOI: 10.1016/j.bmcl.2010.07.033 BindingDB Entry DOI: 10.7270/Q289173T |
More data for this Ligand-Target Pair | |
P2X purinoceptor 7
(Homo sapiens (Human)) | BDBM50416383
(CHEMBL1210558)Show InChI InChI=1S/C14H15Cl2N3O/c1-8-12(9(2)19-18-8)6-14(20)17-7-10-3-4-11(15)5-13(10)16/h3-5H,6-7H2,1-2H3,(H,17,20)(H,18,19) | PDB
KEGG
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| Purchase
CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 7.94 | n/a | n/a | n/a | n/a | n/a | n/a |
GlaxoSmithKline
Curated by ChEMBL
| Assay Description Inhibition of human P2X7 receptor by ethidium bromide release assay |
Bioorg Med Chem Lett 20: 5080-4 (2010)
Article DOI: 10.1016/j.bmcl.2010.07.033 BindingDB Entry DOI: 10.7270/Q289173T |
More data for this Ligand-Target Pair | |
P2X purinoceptor 7
(Homo sapiens (Human)) | BDBM50416618
(CHEMBL1222819)Show SMILES CCN1[C@@H](CCC1=O)C(=O)NCc1cccc(Cl)c1Cl |r| Show InChI InChI=1S/C14H16Cl2N2O2/c1-2-18-11(6-7-12(18)19)14(20)17-8-9-4-3-5-10(15)13(9)16/h3-5,11H,2,6-8H2,1H3,(H,17,20)/t11-/m0/s1 | PDB
KEGG
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 12.6 | n/a | n/a | n/a | n/a | n/a | n/a |
GlaxoSmithKline
Curated by ChEMBL
| Assay Description Inhibition of human P2X7 receptor by ethidium bromide release assay |
Bioorg Med Chem Lett 20: 5080-4 (2010)
Article DOI: 10.1016/j.bmcl.2010.07.033 BindingDB Entry DOI: 10.7270/Q289173T |
More data for this Ligand-Target Pair | |
P2X purinoceptor 7
(Homo sapiens (Human)) | BDBM50416610
(CHEMBL1222673)Show SMILES Fc1ccc(CNC(=O)[C@@H]2CCC(=O)N2C2CCC2)c(Cl)c1 |r| Show InChI InChI=1S/C16H18ClFN2O2/c17-13-8-11(18)5-4-10(13)9-19-16(22)14-6-7-15(21)20(14)12-2-1-3-12/h4-5,8,12,14H,1-3,6-7,9H2,(H,19,22)/t14-/m0/s1 | PDB
KEGG
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 25.1 | n/a | n/a | n/a | n/a | n/a | n/a |
GlaxoSmithKline
Curated by ChEMBL
| Assay Description Inhibition of human P2X7 receptor by ethidium bromide release assay |
Bioorg Med Chem Lett 20: 5080-4 (2010)
Article DOI: 10.1016/j.bmcl.2010.07.033 BindingDB Entry DOI: 10.7270/Q289173T |
More data for this Ligand-Target Pair | |
P2X purinoceptor 7
(Homo sapiens (Human)) | BDBM50416602
(CHEMBL1222882)Show SMILES CCN1[C@@H](CCCC1=O)C(=O)NCc1ccc(F)cc1Cl |r| Show InChI InChI=1S/C15H18ClFN2O2/c1-2-19-13(4-3-5-14(19)20)15(21)18-9-10-6-7-11(17)8-12(10)16/h6-8,13H,2-5,9H2,1H3,(H,18,21)/t13-/m0/s1 | PDB
KEGG
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 31.6 | n/a | n/a | n/a | n/a | n/a | n/a |
GlaxoSmithKline
Curated by ChEMBL
| Assay Description Inhibition of human P2X7 receptor by ethidium bromide release assay |
Bioorg Med Chem Lett 20: 5080-4 (2010)
Article DOI: 10.1016/j.bmcl.2010.07.033 BindingDB Entry DOI: 10.7270/Q289173T |
More data for this Ligand-Target Pair | |
P2X purinoceptor 7
(Homo sapiens (Human)) | BDBM50416607
(CHEMBL1222669)Show InChI InChI=1S/C14H16ClFN2O2/c1-2-18-12(5-6-13(18)19)14(20)17-8-9-3-4-10(16)7-11(9)15/h3-4,7,12H,2,5-6,8H2,1H3,(H,17,20)/t12-/m0/s1 | PDB
KEGG
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 31.6 | n/a | n/a | n/a | n/a | n/a | n/a |
GlaxoSmithKline
Curated by ChEMBL
| Assay Description Inhibition of human P2X7 receptor by ethidium bromide release assay |
Bioorg Med Chem Lett 20: 5080-4 (2010)
Article DOI: 10.1016/j.bmcl.2010.07.033 BindingDB Entry DOI: 10.7270/Q289173T |
More data for this Ligand-Target Pair | |
P2X purinoceptor 7
(Homo sapiens (Human)) | BDBM50415883
(CHEMBL1095454)Show SMILES Cc1nn(c(C)c1CC(=O)NCc1ccc(F)cc1Cl)-c1ccccc1 Show InChI InChI=1S/C20H19ClFN3O/c1-13-18(14(2)25(24-13)17-6-4-3-5-7-17)11-20(26)23-12-15-8-9-16(22)10-19(15)21/h3-10H,11-12H2,1-2H3,(H,23,26) | PDB
KEGG
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 39.8 | n/a | n/a | n/a | n/a | n/a | n/a |
GlaxoSmithKline
Curated by ChEMBL
| Assay Description Inhibition of human P2X7 receptor by ethidium bromide release assay |
Bioorg Med Chem Lett 20: 5080-4 (2010)
Article DOI: 10.1016/j.bmcl.2010.07.033 BindingDB Entry DOI: 10.7270/Q289173T |
More data for this Ligand-Target Pair | |
P2X purinoceptor 7
(Homo sapiens (Human)) | BDBM50416613
(CHEMBL1222739)Show SMILES CCN1[C@@H](CCC1=O)C(=O)NCC12CC3CC(CC(C3)C1)C2 |r,TLB:11:12:15:19.18.17,THB:13:14:17:21.12.20,13:12:15.14.19:17,20:12:15:19.18.17,20:18:15:21.13.12| Show InChI InChI=1S/C18H28N2O2/c1-2-20-15(3-4-16(20)21)17(22)19-11-18-8-12-5-13(9-18)7-14(6-12)10-18/h12-15H,2-11H2,1H3,(H,19,22)/t12?,13?,14?,15-,18?/m0/s1 | PDB
KEGG
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 79.4 | n/a | n/a | n/a | n/a | n/a | n/a |
GlaxoSmithKline
Curated by ChEMBL
| Assay Description Inhibition of human P2X7 receptor by ethidium bromide release assay |
Bioorg Med Chem Lett 20: 5080-4 (2010)
Article DOI: 10.1016/j.bmcl.2010.07.033 BindingDB Entry DOI: 10.7270/Q289173T |
More data for this Ligand-Target Pair | |
P2X purinoceptor 7
(Rattus norvegicus (Rat)) | BDBM50416383
(CHEMBL1210558)Show InChI InChI=1S/C14H15Cl2N3O/c1-8-12(9(2)19-18-8)6-14(20)17-7-10-3-4-11(15)5-13(10)16/h3-5H,6-7H2,1-2H3,(H,17,20)(H,18,19) | PDB
KEGG
UniProtKB/SwissProt
GoogleScholar AffyNet
| Purchase
CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 79.4 | n/a | n/a | n/a | n/a | n/a | n/a |
GlaxoSmithKline
Curated by ChEMBL
| Assay Description Inhibition of rat P2X7 receptor by ethidium bromide release assay |
Bioorg Med Chem Lett 20: 5080-4 (2010)
Article DOI: 10.1016/j.bmcl.2010.07.033 BindingDB Entry DOI: 10.7270/Q289173T |
More data for this Ligand-Target Pair | |
P2X purinoceptor 7
(Homo sapiens (Human)) | BDBM50416600
(CHEMBL1222823)Show InChI InChI=1S/C14H16ClFN2O2/c1-9(19)18-6-2-3-13(18)14(20)17-8-10-4-5-11(16)7-12(10)15/h4-5,7,13H,2-3,6,8H2,1H3,(H,17,20)/t13-/m0/s1 | PDB
KEGG
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 100 | n/a | n/a | n/a | n/a | n/a | n/a |
GlaxoSmithKline
Curated by ChEMBL
| Assay Description Inhibition of human P2X7 receptor by ethidium bromide release assay |
Bioorg Med Chem Lett 20: 5080-4 (2010)
Article DOI: 10.1016/j.bmcl.2010.07.033 BindingDB Entry DOI: 10.7270/Q289173T |
More data for this Ligand-Target Pair | |
P2X purinoceptor 7
(Rattus norvegicus (Rat)) | BDBM50415883
(CHEMBL1095454)Show SMILES Cc1nn(c(C)c1CC(=O)NCc1ccc(F)cc1Cl)-c1ccccc1 Show InChI InChI=1S/C20H19ClFN3O/c1-13-18(14(2)25(24-13)17-6-4-3-5-7-17)11-20(26)23-12-15-8-9-16(22)10-19(15)21/h3-10H,11-12H2,1-2H3,(H,23,26) | PDB
KEGG
UniProtKB/SwissProt
GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 100 | n/a | n/a | n/a | n/a | n/a | n/a |
GlaxoSmithKline
Curated by ChEMBL
| Assay Description Inhibition of rat P2X7 receptor by ethidium bromide release assay |
Bioorg Med Chem Lett 20: 5080-4 (2010)
Article DOI: 10.1016/j.bmcl.2010.07.033 BindingDB Entry DOI: 10.7270/Q289173T |
More data for this Ligand-Target Pair | |
P2X purinoceptor 7
(Homo sapiens (Human)) | BDBM50416606
(CHEMBL1222606)Show InChI InChI=1S/C13H14ClFN2O2/c1-17-11(4-5-12(17)18)13(19)16-7-8-2-3-9(15)6-10(8)14/h2-3,6,11H,4-5,7H2,1H3,(H,16,19)/t11-/m0/s1 | PDB
KEGG
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 100 | n/a | n/a | n/a | n/a | n/a | n/a |
GlaxoSmithKline
Curated by ChEMBL
| Assay Description Inhibition of human P2X7 receptor by ethidium bromide release assay |
Bioorg Med Chem Lett 20: 5080-4 (2010)
Article DOI: 10.1016/j.bmcl.2010.07.033 BindingDB Entry DOI: 10.7270/Q289173T |
More data for this Ligand-Target Pair | |
P2X purinoceptor 7
(Homo sapiens (Human)) | BDBM50416617
(CHEMBL1222743)Show SMILES CCN1[C@@H](CCC1=O)C(=O)NCc1cccc(c1)C(F)(F)F |r| Show InChI InChI=1S/C15H17F3N2O2/c1-2-20-12(6-7-13(20)21)14(22)19-9-10-4-3-5-11(8-10)15(16,17)18/h3-5,8,12H,2,6-7,9H2,1H3,(H,19,22)/t12-/m0/s1 | PDB
KEGG
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 100 | n/a | n/a | n/a | n/a | n/a | n/a |
GlaxoSmithKline
Curated by ChEMBL
| Assay Description Inhibition of human P2X7 receptor by ethidium bromide release assay |
Bioorg Med Chem Lett 20: 5080-4 (2010)
Article DOI: 10.1016/j.bmcl.2010.07.033 BindingDB Entry DOI: 10.7270/Q289173T |
More data for this Ligand-Target Pair | |
P2X purinoceptor 7
(Homo sapiens (Human)) | BDBM50416604
(CHEMBL1222604)Show SMILES CC(C)N1[C@@H](CCC1=O)C(=O)NCc1ccc(F)cc1Cl |r| Show InChI InChI=1S/C15H18ClFN2O2/c1-9(2)19-13(5-6-14(19)20)15(21)18-8-10-3-4-11(17)7-12(10)16/h3-4,7,9,13H,5-6,8H2,1-2H3,(H,18,21)/t13-/m0/s1 | PDB
KEGG
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 100 | n/a | n/a | n/a | n/a | n/a | n/a |
GlaxoSmithKline
Curated by ChEMBL
| Assay Description Inhibition of human P2X7 receptor by ethidium bromide release assay |
Bioorg Med Chem Lett 20: 5080-4 (2010)
Article DOI: 10.1016/j.bmcl.2010.07.033 BindingDB Entry DOI: 10.7270/Q289173T |
More data for this Ligand-Target Pair | |
P2X purinoceptor 7
(Homo sapiens (Human)) | BDBM50416605
(CHEMBL1222602)Show SMILES CN(C(=O)c1cc(Cl)c(=O)n(Cc2c(Cl)cccc2Cl)c1)c1ccccc1 Show InChI InChI=1S/C20H15Cl3N2O2/c1-24(14-6-3-2-4-7-14)19(26)13-10-18(23)20(27)25(11-13)12-15-16(21)8-5-9-17(15)22/h2-11H,12H2,1H3 | PDB
KEGG
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| Purchase
CHEMBL PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 126 | n/a | n/a | n/a | n/a | n/a | n/a |
GlaxoSmithKline
Curated by ChEMBL
| Assay Description Inhibition of human P2X7 receptor by ethidium bromide release assay |
Bioorg Med Chem Lett 20: 5080-4 (2010)
Article DOI: 10.1016/j.bmcl.2010.07.033 BindingDB Entry DOI: 10.7270/Q289173T |
More data for this Ligand-Target Pair | |
P2X purinoceptor 7
(Homo sapiens (Human)) | BDBM50416608
(CHEMBL1222670)Show SMILES CCCN1[C@@H](CCC1=O)C(=O)NCc1ccc(F)cc1Cl |r| Show InChI InChI=1S/C15H18ClFN2O2/c1-2-7-19-13(5-6-14(19)20)15(21)18-9-10-3-4-11(17)8-12(10)16/h3-4,8,13H,2,5-7,9H2,1H3,(H,18,21)/t13-/m0/s1 | PDB
KEGG
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 158 | n/a | n/a | n/a | n/a | n/a | n/a |
GlaxoSmithKline
Curated by ChEMBL
| Assay Description Inhibition of human P2X7 receptor by ethidium bromide release assay |
Bioorg Med Chem Lett 20: 5080-4 (2010)
Article DOI: 10.1016/j.bmcl.2010.07.033 BindingDB Entry DOI: 10.7270/Q289173T |
More data for this Ligand-Target Pair | |
P2X purinoceptor 7
(Homo sapiens (Human)) | BDBM50416601
(CHEMBL1222881)Show InChI InChI=1S/C14H16ClFN2O2/c1-2-18-12(5-6-13(18)19)14(20)17-8-9-3-4-10(16)7-11(9)15/h3-4,7,12H,2,5-6,8H2,1H3,(H,17,20)/t12-/m1/s1 | PDB
KEGG
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 158 | n/a | n/a | n/a | n/a | n/a | n/a |
GlaxoSmithKline
Curated by ChEMBL
| Assay Description Inhibition of human P2X7 receptor by ethidium bromide release assay |
Bioorg Med Chem Lett 20: 5080-4 (2010)
Article DOI: 10.1016/j.bmcl.2010.07.033 BindingDB Entry DOI: 10.7270/Q289173T |
More data for this Ligand-Target Pair | |
P2X purinoceptor 7
(Homo sapiens (Human)) | BDBM50416604
(CHEMBL1222604)Show SMILES CC(C)N1[C@@H](CCC1=O)C(=O)NCc1ccc(F)cc1Cl |r| Show InChI InChI=1S/C15H18ClFN2O2/c1-9(2)19-13(5-6-14(19)20)15(21)18-8-10-3-4-11(17)7-12(10)16/h3-4,7,9,13H,5-6,8H2,1-2H3,(H,18,21)/t13-/m0/s1 | PDB
KEGG
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 316 | n/a | n/a | n/a | n/a | n/a | n/a |
GlaxoSmithKline
Curated by ChEMBL
| Assay Description Inhibition of human P2X7 receptor by ethidium bromide release assay |
Bioorg Med Chem Lett 20: 5080-4 (2010)
Article DOI: 10.1016/j.bmcl.2010.07.033 BindingDB Entry DOI: 10.7270/Q289173T |
More data for this Ligand-Target Pair | |
P2X purinoceptor 7
(Rattus norvegicus (Rat)) | BDBM50416603
(CHEMBL1222883)Show SMILES CN1[C@@H](CCC1=O)C(=O)NCc1cccc(c1Cl)C(F)(F)F |r| Show InChI InChI=1S/C14H14ClF3N2O2/c1-20-10(5-6-11(20)21)13(22)19-7-8-3-2-4-9(12(8)15)14(16,17)18/h2-4,10H,5-7H2,1H3,(H,19,22)/t10-/m0/s1 | PDB
KEGG
UniProtKB/SwissProt
GoogleScholar AffyNet
| Purchase
CHEMBL MCE PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 316 | n/a | n/a | n/a | n/a | n/a | n/a |
GlaxoSmithKline
Curated by ChEMBL
| Assay Description Inhibition of rat P2X7 receptor by ethidium bromide release assay |
Bioorg Med Chem Lett 20: 5080-4 (2010)
Article DOI: 10.1016/j.bmcl.2010.07.033 BindingDB Entry DOI: 10.7270/Q289173T |
More data for this Ligand-Target Pair | |
P2X purinoceptor 7
(Rattus norvegicus (Rat)) | BDBM50416605
(CHEMBL1222602)Show SMILES CN(C(=O)c1cc(Cl)c(=O)n(Cc2c(Cl)cccc2Cl)c1)c1ccccc1 Show InChI InChI=1S/C20H15Cl3N2O2/c1-24(14-6-3-2-4-7-14)19(26)13-10-18(23)20(27)25(11-13)12-15-16(21)8-5-9-17(15)22/h2-11H,12H2,1H3 | PDB
KEGG
UniProtKB/SwissProt
GoogleScholar AffyNet
| Purchase
CHEMBL PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 316 | n/a | n/a | n/a | n/a | n/a | n/a |
GlaxoSmithKline
Curated by ChEMBL
| Assay Description Inhibition of rat P2X7 receptor by ethidium bromide release assay |
Bioorg Med Chem Lett 20: 5080-4 (2010)
Article DOI: 10.1016/j.bmcl.2010.07.033 BindingDB Entry DOI: 10.7270/Q289173T |
More data for this Ligand-Target Pair | |
P2X purinoceptor 7
(Homo sapiens (Human)) | BDBM50416609
(CHEMBL1222671)Show SMILES CC(C)CN1[C@@H](CCC1=O)C(=O)NCc1ccc(F)cc1Cl |r| Show InChI InChI=1S/C16H20ClFN2O2/c1-10(2)9-20-14(5-6-15(20)21)16(22)19-8-11-3-4-12(18)7-13(11)17/h3-4,7,10,14H,5-6,8-9H2,1-2H3,(H,19,22)/t14-/m0/s1 | PDB
KEGG
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 398 | n/a | n/a | n/a | n/a | n/a | n/a |
GlaxoSmithKline
Curated by ChEMBL
| Assay Description Inhibition of human P2X7 receptor by ethidium bromide release assay |
Bioorg Med Chem Lett 20: 5080-4 (2010)
Article DOI: 10.1016/j.bmcl.2010.07.033 BindingDB Entry DOI: 10.7270/Q289173T |
More data for this Ligand-Target Pair | |
P2X purinoceptor 7
(Homo sapiens (Human)) | BDBM50416611
(CHEMBL1222519)Show SMILES Fc1ccc(CNC(=O)[C@@H]2CCC(=O)N2C2CCCC2)c(Cl)c1 |r| Show InChI InChI=1S/C17H20ClFN2O2/c18-14-9-12(19)6-5-11(14)10-20-17(23)15-7-8-16(22)21(15)13-3-1-2-4-13/h5-6,9,13,15H,1-4,7-8,10H2,(H,20,23)/t15-/m0/s1 | PDB
KEGG
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 501 | n/a | n/a | n/a | n/a | n/a | n/a |
GlaxoSmithKline
Curated by ChEMBL
| Assay Description Inhibition of human P2X7 receptor by ethidium bromide release assay |
Bioorg Med Chem Lett 20: 5080-4 (2010)
Article DOI: 10.1016/j.bmcl.2010.07.033 BindingDB Entry DOI: 10.7270/Q289173T |
More data for this Ligand-Target Pair | |
P2X purinoceptor 7
(Homo sapiens (Human)) | BDBM50416614
(CHEMBL1222742)Show InChI InChI=1S/C14H17ClN2O2/c1-2-17-12(7-8-13(17)18)14(19)16-9-10-3-5-11(15)6-4-10/h3-6,12H,2,7-9H2,1H3,(H,16,19)/t12-/m0/s1 | PDB
KEGG
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 631 | n/a | n/a | n/a | n/a | n/a | n/a |
GlaxoSmithKline
Curated by ChEMBL
| Assay Description Inhibition of human P2X7 receptor by ethidium bromide release assay |
Bioorg Med Chem Lett 20: 5080-4 (2010)
Article DOI: 10.1016/j.bmcl.2010.07.033 BindingDB Entry DOI: 10.7270/Q289173T |
More data for this Ligand-Target Pair | |
P2X purinoceptor 7
(Homo sapiens (Human)) | BDBM50416615
(CHEMBL1222744)Show SMILES CCN1[C@@H](CCC1=O)C(=O)NCc1ccccc1C(F)(F)F |r| Show InChI InChI=1S/C15H17F3N2O2/c1-2-20-12(7-8-13(20)21)14(22)19-9-10-5-3-4-6-11(10)15(16,17)18/h3-6,12H,2,7-9H2,1H3,(H,19,22)/t12-/m0/s1 | PDB
KEGG
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 631 | n/a | n/a | n/a | n/a | n/a | n/a |
GlaxoSmithKline
Curated by ChEMBL
| Assay Description Inhibition of human P2X7 receptor by ethidium bromide release assay |
Bioorg Med Chem Lett 20: 5080-4 (2010)
Article DOI: 10.1016/j.bmcl.2010.07.033 BindingDB Entry DOI: 10.7270/Q289173T |
More data for this Ligand-Target Pair | |
P2X purinoceptor 7
(Homo sapiens (Human)) | BDBM50416616
(CHEMBL1222740)Show InChI InChI=1S/C14H17ClN2O2/c1-2-17-12(7-8-13(17)18)14(19)16-9-10-5-3-4-6-11(10)15/h3-6,12H,2,7-9H2,1H3,(H,16,19)/t12-/m0/s1 | PDB
KEGG
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 631 | n/a | n/a | n/a | n/a | n/a | n/a |
GlaxoSmithKline
Curated by ChEMBL
| Assay Description Inhibition of human P2X7 receptor by ethidium bromide release assay |
Bioorg Med Chem Lett 20: 5080-4 (2010)
Article DOI: 10.1016/j.bmcl.2010.07.033 BindingDB Entry DOI: 10.7270/Q289173T |
More data for this Ligand-Target Pair | |
P2X purinoceptor 7
(Homo sapiens (Human)) | BDBM50416612
(CHEMBL1222601)Show SMILES Fc1ccc(CNC(=O)[C@@H]2CCC(=O)N2c2ccccc2)c(Cl)c1 |r| Show InChI InChI=1S/C18H16ClFN2O2/c19-15-10-13(20)7-6-12(15)11-21-18(24)16-8-9-17(23)22(16)14-4-2-1-3-5-14/h1-7,10,16H,8-9,11H2,(H,21,24)/t16-/m0/s1 | PDB
KEGG
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 794 | n/a | n/a | n/a | n/a | n/a | n/a |
GlaxoSmithKline
Curated by ChEMBL
| Assay Description Inhibition of human P2X7 receptor by ethidium bromide release assay |
Bioorg Med Chem Lett 20: 5080-4 (2010)
Article DOI: 10.1016/j.bmcl.2010.07.033 BindingDB Entry DOI: 10.7270/Q289173T |
More data for this Ligand-Target Pair | |
P2X purinoceptor 7
(Rattus norvegicus (Rat)) | BDBM50416604
(CHEMBL1222604)Show SMILES CC(C)N1[C@@H](CCC1=O)C(=O)NCc1ccc(F)cc1Cl |r| Show InChI InChI=1S/C15H18ClFN2O2/c1-9(2)19-13(5-6-14(19)20)15(21)18-8-10-3-4-11(17)7-12(10)16/h3-4,7,9,13H,5-6,8H2,1-2H3,(H,18,21)/t13-/m0/s1 | PDB
KEGG
UniProtKB/SwissProt
GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 1.58E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
GlaxoSmithKline
Curated by ChEMBL
| Assay Description Inhibition of rat P2X7 receptor by ethidium bromide release assay |
Bioorg Med Chem Lett 20: 5080-4 (2010)
Article DOI: 10.1016/j.bmcl.2010.07.033 BindingDB Entry DOI: 10.7270/Q289173T |
More data for this Ligand-Target Pair | |
P2X purinoceptor 7
(Rattus norvegicus (Rat)) | BDBM50416604
(CHEMBL1222604)Show SMILES CC(C)N1[C@@H](CCC1=O)C(=O)NCc1ccc(F)cc1Cl |r| Show InChI InChI=1S/C15H18ClFN2O2/c1-9(2)19-13(5-6-14(19)20)15(21)18-8-10-3-4-11(17)7-12(10)16/h3-4,7,9,13H,5-6,8H2,1-2H3,(H,18,21)/t13-/m0/s1 | PDB
KEGG
UniProtKB/SwissProt
GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
GlaxoSmithKline
Curated by ChEMBL
| Assay Description Inhibition of rat P2X7 receptor by ethidium bromide release assay |
Bioorg Med Chem Lett 20: 5080-4 (2010)
Article DOI: 10.1016/j.bmcl.2010.07.033 BindingDB Entry DOI: 10.7270/Q289173T |
More data for this Ligand-Target Pair | |