Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
11-beta-hydroxysteroid dehydrogenase 1 (Homo sapiens (Human)) | BDBM50117901 (2-(2-(3-chloro-2-methylphenylsulfonamido)thiazol-4...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars | PubMed | n/a | n/a | 52 | n/a | n/a | n/a | n/a | n/a | n/a |
Biovitrum Curated by ChEMBL | Assay Description In vitro inhibitory activity against human 11 beta hydroxysteroid dehydrogenase type 1 using scintillation proximity assay (SPA) | J Med Chem 45: 3813-5 (2002) BindingDB Entry DOI: 10.7270/Q2S46SPW | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
11-beta-hydroxysteroid dehydrogenase 1 (Homo sapiens (Human)) | BDBM50247012 (3beta-O-Succinyl-18-beta-glycyrrhetinic acid | Car...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase MCE MMDB PC cid PC sid PDB UniChem Patents Similars | PDB PubMed | n/a | n/a | 83 | n/a | n/a | n/a | n/a | n/a | n/a |
Biovitrum Curated by ChEMBL | Assay Description Ability to convert [3H]cortisol to the tritium labeled cortisone in the presence of human 11 beta hydroxysteroid dehydrogenase type 2 | J Med Chem 45: 3813-5 (2002) BindingDB Entry DOI: 10.7270/Q2S46SPW | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (crystal) | ||||||||||||
11-beta-hydroxysteroid dehydrogenase 1 (Mus musculus (mouse)) | BDBM50117900 (3-Chloro-2-methyl-N-{4-[2-(4-methyl-piperazin-1-yl...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | Purchase CHEMBL MCE PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 96 | n/a | n/a | n/a | n/a | n/a | n/a |
Biovitrum Curated by ChEMBL | Assay Description In vitro inhibitory activity against mouse 11 beta hydroxysteroid dehydrogenase type 1 using scintillation proximity assay (SPA) | J Med Chem 45: 3813-5 (2002) BindingDB Entry DOI: 10.7270/Q2S46SPW | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
11-beta-hydroxysteroid dehydrogenase 1 (Mus musculus (mouse)) | BDBM50247012 (3beta-O-Succinyl-18-beta-glycyrrhetinic acid | Car...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | Purchase MCE MMDB PC cid PC sid PDB UniChem Patents Similars | PubMed | n/a | n/a | 108 | n/a | n/a | n/a | n/a | n/a | n/a |
Biovitrum Curated by ChEMBL | Assay Description In vitro inhibitory activity against mouse 11 beta hydroxysteroid dehydrogenase type 1 using scintillation proximity assay (SPA). | J Med Chem 45: 3813-5 (2002) BindingDB Entry DOI: 10.7270/Q2S46SPW | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
11-beta-hydroxysteroid dehydrogenase 1 (Mus musculus (mouse)) | BDBM50117901 (2-(2-(3-chloro-2-methylphenylsulfonamido)thiazol-4...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars | PubMed | n/a | n/a | 284 | n/a | n/a | n/a | n/a | n/a | n/a |
Biovitrum Curated by ChEMBL | Assay Description In vitro inhibitory activity against mouse 11 beta hydroxysteroid dehydrogenase type 1 using scintillation proximity assay (SPA). | J Med Chem 45: 3813-5 (2002) BindingDB Entry DOI: 10.7270/Q2S46SPW | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
11-beta-hydroxysteroid dehydrogenase 1 (Homo sapiens (Human)) | BDBM50247012 (3beta-O-Succinyl-18-beta-glycyrrhetinic acid | Car...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase MCE MMDB PC cid PC sid PDB UniChem Patents Similars | PDB PubMed | n/a | n/a | 330 | n/a | n/a | n/a | n/a | n/a | n/a |
Biovitrum Curated by ChEMBL | Assay Description In vitro inhibitory activity against human 11 beta hydroxysteroid dehydrogenase type 1 using scintillation proximity assay (SPA) | J Med Chem 45: 3813-5 (2002) BindingDB Entry DOI: 10.7270/Q2S46SPW | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (crystal) | ||||||||||||
11-beta-hydroxysteroid dehydrogenase 1 (Homo sapiens (Human)) | BDBM50117900 (3-Chloro-2-methyl-N-{4-[2-(4-methyl-piperazin-1-yl...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL MCE PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 3.34E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Biovitrum Curated by ChEMBL | Assay Description In vitro inhibitory activity against human 11 beta hydroxysteroid dehydrogenase type 1 using scintillation proximity assay (SPA) | J Med Chem 45: 3813-5 (2002) BindingDB Entry DOI: 10.7270/Q2S46SPW | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
11-beta-hydroxysteroid dehydrogenase 1 (Homo sapiens (Human)) | BDBM50117901 (2-(2-(3-chloro-2-methylphenylsulfonamido)thiazol-4...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars | PubMed | n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Biovitrum Curated by ChEMBL | Assay Description Ability to convert [3H]cortisol to the tritium labeled cortisone in the presence of human 11 beta hydroxysteroid dehydrogenase type 2 | J Med Chem 45: 3813-5 (2002) BindingDB Entry DOI: 10.7270/Q2S46SPW | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
11-beta-hydroxysteroid dehydrogenase 1 (Homo sapiens (Human)) | BDBM50117900 (3-Chloro-2-methyl-N-{4-[2-(4-methyl-piperazin-1-yl...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL MCE PC cid PC sid UniChem Similars | PubMed | n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Biovitrum Curated by ChEMBL | Assay Description Ability to convert [3H]cortisol to the tritium labeled cortisone in the presence of human 11 beta hydroxysteroid dehydrogenase type 2 | J Med Chem 45: 3813-5 (2002) BindingDB Entry DOI: 10.7270/Q2S46SPW | |||||||||||
More data for this Ligand-Target Pair |