Compile Data Set for Download or QSAR

Found 17 hits with Last Name = 'acklam' and Initial = 'p'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Dihydroorotate dehydrogenase (quinone), mitochondrial (Homo sapiens (Human))	BDBM50397816 (CHEMBL2177861) Show SMILES CCc1cc(=O)n2[nH]c(SCc3cc(Cl)ccc3Cl)nc2n1 Show InChI InChI=1S/C14H12Cl2N4OS/c1-2-10-6-12(21)20-13(17-10)18-14(19-20)22-7-8-5-9(15)3-4-11(8)16/h3-6H,2,7H2,1H3,(H,17,18,19)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	13	n/a	n/a	n/a	n/a	n/a	n/a
University of Leeds Curated by ChEMBL					Assay Description Inhibition of human dihydroorate dehydrogenase expressed in Escherichia coli BL21(DE3) using dihydroorate as substrate by DCIP-based colorimetric ana...				J Med Chem 55: 5841-50 (2012) Article DOI: 10.1021/jm300157n BindingDB Entry DOI: 10.7270/Q2HT2QG8
					More data for this Ligand-Target Pair
Dihydroorotate dehydrogenase (quinone), mitochondrial (Homo sapiens (Human))	BDBM50397819 (CHEMBL2177858) Show SMILES Cc1cc(=O)n2[nH]c(SCc3cc(Cl)ccc3Cl)nc2n1 Show InChI InChI=1S/C13H10Cl2N4OS/c1-7-4-11(20)19-12(16-7)17-13(18-19)21-6-8-5-9(14)2-3-10(8)15/h2-5H,6H2,1H3,(H,16,17,18)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	51	n/a	n/a	n/a	n/a	n/a	n/a
University of Leeds Curated by ChEMBL					Assay Description Inhibition of human dihydroorate dehydrogenase expressed in Escherichia coli BL21(DE3) using dihydroorate as substrate by DCIP-based colorimetric ana...				J Med Chem 55: 5841-50 (2012) Article DOI: 10.1021/jm300157n BindingDB Entry DOI: 10.7270/Q2HT2QG8
					More data for this Ligand-Target Pair
Dihydroorotate dehydrogenase (quinone), mitochondrial (Homo sapiens (Human))	BDBM50397821 (CHEMBL2177856) Show SMILES Cc1cc(=O)n2[nH]c(SCc3ccc(Cl)c(Cl)c3)nc2n1 Show InChI InChI=1S/C13H10Cl2N4OS/c1-7-4-11(20)19-12(16-7)17-13(18-19)21-6-8-2-3-9(14)10(15)5-8/h2-5H,6H2,1H3,(H,16,17,18)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	6.50E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Leeds Curated by ChEMBL					Assay Description Inhibition of human dihydroorate dehydrogenase expressed in Escherichia coli BL21(DE3) using dihydroorate as substrate by DCIP-based colorimetric ana...				J Med Chem 55: 5841-50 (2012) Article DOI: 10.1021/jm300157n BindingDB Entry DOI: 10.7270/Q2HT2QG8
					More data for this Ligand-Target Pair
Dihydroorotate dehydrogenase (quinone), mitochondrial (Homo sapiens (Human))	BDBM50397823 (CHEMBL2177855) Show SMILES Cc1cc(=O)n2[nH]c(SCc3ccccc3[N+]([O-])=O)nc2n1 Show InChI InChI=1S/C13H11N5O3S/c1-8-6-11(19)17-12(14-8)15-13(16-17)22-7-9-4-2-3-5-10(9)18(20)21/h2-6H,7H2,1H3,(H,14,15,16)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	9.50E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Leeds Curated by ChEMBL					Assay Description Inhibition of human dihydroorate dehydrogenase expressed in Escherichia coli BL21(DE3) using dihydroorate as substrate by DCIP-based colorimetric ana...				J Med Chem 55: 5841-50 (2012) Article DOI: 10.1021/jm300157n BindingDB Entry DOI: 10.7270/Q2HT2QG8
					More data for this Ligand-Target Pair
Dihydroorotate dehydrogenase (quinone), mitochondrial (Homo sapiens (Human))	BDBM50397828 (CHEMBL1599552) Show SMILES Cc1cc(=O)n2[nH]c(SCc3ccccc3Cl)nc2n1 Show InChI InChI=1S/C13H11ClN4OS/c1-8-6-11(19)18-12(15-8)16-13(17-18)20-7-9-4-2-3-5-10(9)14/h2-6H,7H2,1H3,(H,15,16,17)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.20E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Leeds Curated by ChEMBL					Assay Description Inhibition of human dihydroorate dehydrogenase expressed in Escherichia coli BL21(DE3) using dihydroorate as substrate by DCIP-based colorimetric ana...				J Med Chem 55: 5841-50 (2012) Article DOI: 10.1021/jm300157n BindingDB Entry DOI: 10.7270/Q2HT2QG8
					More data for this Ligand-Target Pair
Dihydroorotate dehydrogenase (quinone), mitochondrial (Homo sapiens (Human))	BDBM50397817 (CHEMBL2177860) Show SMILES CCc1cc(=O)n2[nH]c(SCc3ccc(Cl)cc3)nc2n1 Show InChI InChI=1S/C14H13ClN4OS/c1-2-11-7-12(20)19-13(16-11)17-14(18-19)21-8-9-3-5-10(15)6-4-9/h3-7H,2,8H2,1H3,(H,16,17,18)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.30E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Leeds Curated by ChEMBL					Assay Description Inhibition of human dihydroorate dehydrogenase expressed in Escherichia coli BL21(DE3) using dihydroorate as substrate by DCIP-based colorimetric ana...				J Med Chem 55: 5841-50 (2012) Article DOI: 10.1021/jm300157n BindingDB Entry DOI: 10.7270/Q2HT2QG8
					More data for this Ligand-Target Pair
Dihydroorotate dehydrogenase (quinone), mitochondrial (Homo sapiens (Human))	BDBM50397820 (CHEMBL2177857) Show SMILES Cc1cc(=O)n2[nH]c(SCc3c(Cl)cccc3Cl)nc2n1 Show InChI InChI=1S/C13H10Cl2N4OS/c1-7-5-11(20)19-12(16-7)17-13(18-19)21-6-8-9(14)3-2-4-10(8)15/h2-5H,6H2,1H3,(H,16,17,18)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.80E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Leeds Curated by ChEMBL					Assay Description Inhibition of human dihydroorate dehydrogenase expressed in Escherichia coli BL21(DE3) using dihydroorate as substrate by DCIP-based colorimetric ana...				J Med Chem 55: 5841-50 (2012) Article DOI: 10.1021/jm300157n BindingDB Entry DOI: 10.7270/Q2HT2QG8
					More data for this Ligand-Target Pair
Dihydroorotate dehydrogenase (quinone), mitochondrial (Homo sapiens (Human))	BDBM50397827 (CHEMBL2178513) Show SMILES Cc1cc(=O)n2[nH]c(SCc3cccc(Cl)c3)nc2n1 Show InChI InChI=1S/C13H11ClN4OS/c1-8-5-11(19)18-12(15-8)16-13(17-18)20-7-9-3-2-4-10(14)6-9/h2-6H,7H2,1H3,(H,15,16,17)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.90E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Leeds Curated by ChEMBL					Assay Description Inhibition of human dihydroorate dehydrogenase expressed in Escherichia coli BL21(DE3) using dihydroorate as substrate by DCIP-based colorimetric ana...				J Med Chem 55: 5841-50 (2012) Article DOI: 10.1021/jm300157n BindingDB Entry DOI: 10.7270/Q2HT2QG8
					More data for this Ligand-Target Pair
Dihydroorotate dehydrogenase (quinone), mitochondrial (Homo sapiens (Human))	BDBM50397818 (CHEMBL2177859) Show SMILES Cc1cc(C)cc(CSc2nc3nc(C)cc(=O)n3[nH]2)c1 Show InChI InChI=1S/C15H16N4OS/c1-9-4-10(2)6-12(5-9)8-21-15-17-14-16-11(3)7-13(20)19(14)18-15/h4-7H,8H2,1-3H3,(H,16,17,18)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Leeds Curated by ChEMBL					Assay Description Inhibition of human dihydroorate dehydrogenase expressed in Escherichia coli BL21(DE3) using dihydroorate as substrate by DCIP-based colorimetric ana...				J Med Chem 55: 5841-50 (2012) Article DOI: 10.1021/jm300157n BindingDB Entry DOI: 10.7270/Q2HT2QG8
					More data for this Ligand-Target Pair
Dihydroorotate dehydrogenase (quinone), mitochondrial (Homo sapiens (Human))	BDBM50397825 (CHEMBL2177853) Show SMILES Cc1cc(=O)n2[nH]c(SCc3ccc(Br)cc3)nc2n1 Show InChI InChI=1S/C13H11BrN4OS/c1-8-6-11(19)18-12(15-8)16-13(17-18)20-7-9-2-4-10(14)5-3-9/h2-6H,7H2,1H3,(H,15,16,17)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.20E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Leeds Curated by ChEMBL					Assay Description Inhibition of human dihydroorate dehydrogenase expressed in Escherichia coli BL21(DE3) using dihydroorate as substrate by DCIP-based colorimetric ana...				J Med Chem 55: 5841-50 (2012) Article DOI: 10.1021/jm300157n BindingDB Entry DOI: 10.7270/Q2HT2QG8
					More data for this Ligand-Target Pair
Dihydroorotate dehydrogenase (quinone), mitochondrial (Homo sapiens (Human))	BDBM50397829 (CHEMBL1704856) Show SMILES Cc1cc(=O)n2[nH]c(SCc3ccc(Cl)cc3)nc2n1 Show InChI InChI=1S/C13H11ClN4OS/c1-8-6-11(19)18-12(15-8)16-13(17-18)20-7-9-2-4-10(14)5-3-9/h2-6H,7H2,1H3,(H,15,16,17)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.90E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Leeds Curated by ChEMBL					Assay Description Inhibition of human dihydroorate dehydrogenase expressed in Escherichia coli BL21(DE3) using dihydroorate as substrate by DCIP-based colorimetric ana...				J Med Chem 55: 5841-50 (2012) Article DOI: 10.1021/jm300157n BindingDB Entry DOI: 10.7270/Q2HT2QG8
					More data for this Ligand-Target Pair
Dihydroorotate dehydrogenase (quinone), mitochondrial (Homo sapiens (Human))	BDBM50397826 (CHEMBL2178514) Show SMILES Cc1ccc(CSc2nc3nc(C)cc(=O)n3[nH]2)cc1 Show InChI InChI=1S/C14H14N4OS/c1-9-3-5-11(6-4-9)8-20-14-16-13-15-10(2)7-12(19)18(13)17-14/h3-7H,8H2,1-2H3,(H,15,16,17)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	4.60E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Leeds Curated by ChEMBL					Assay Description Inhibition of human dihydroorate dehydrogenase expressed in Escherichia coli BL21(DE3) using dihydroorate as substrate by DCIP-based colorimetric ana...				J Med Chem 55: 5841-50 (2012) Article DOI: 10.1021/jm300157n BindingDB Entry DOI: 10.7270/Q2HT2QG8
					More data for this Ligand-Target Pair
Dihydroorotate dehydrogenase (quinone), mitochondrial (Homo sapiens (Human))	BDBM50397824 (CHEMBL2177854) Show SMILES COc1ccc(CSc2nc3nc(C)cc(=O)n3[nH]2)cc1 Show InChI InChI=1S/C14H14N4O2S/c1-9-7-12(19)18-13(15-9)16-14(17-18)21-8-10-3-5-11(20-2)6-4-10/h3-7H,8H2,1-2H3,(H,15,16,17)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	6.30E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Leeds Curated by ChEMBL					Assay Description Inhibition of human dihydroorate dehydrogenase expressed in Escherichia coli BL21(DE3) using dihydroorate as substrate by DCIP-based colorimetric ana...				J Med Chem 55: 5841-50 (2012) Article DOI: 10.1021/jm300157n BindingDB Entry DOI: 10.7270/Q2HT2QG8
					More data for this Ligand-Target Pair
Dihydroorotate dehydrogenase (quinone), mitochondrial (Homo sapiens (Human))	BDBM50397822 (CHEMBL135703) Show SMILES Cc1cc(=O)n2[nH]c(SCc3ccccc3)nc2n1 Show InChI InChI=1S/C13H12N4OS/c1-9-7-11(18)17-12(14-9)15-13(16-17)19-8-10-5-3-2-4-6-10/h2-7H,8H2,1H3,(H,14,15,16)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	8.90E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Leeds Curated by ChEMBL					Assay Description Inhibition of human dihydroorate dehydrogenase expressed in Escherichia coli BL21(DE3) using dihydroorate as substrate by DCIP-based colorimetric ana...				J Med Chem 55: 5841-50 (2012) Article DOI: 10.1021/jm300157n BindingDB Entry DOI: 10.7270/Q2HT2QG8
					More data for this Ligand-Target Pair
Dihydroorotate dehydrogenase (quinone), mitochondrial (Homo sapiens (Human))	BDBM50397815 (CHEMBL2177862) Show SMILES Cc1cc(N)n2nc(SCc3ccccc3)nc2n1 Show InChI InChI=1S/C13H13N5S/c1-9-7-11(14)18-12(15-9)16-13(17-18)19-8-10-5-3-2-4-6-10/h2-7H,8,14H2,1H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
University of Leeds Curated by ChEMBL					Assay Description Inhibition of human dihydroorate dehydrogenase expressed in Escherichia coli BL21(DE3) using dihydroorate as substrate by DCIP-based colorimetric ana...				J Med Chem 55: 5841-50 (2012) Article DOI: 10.1021/jm300157n BindingDB Entry DOI: 10.7270/Q2HT2QG8
					More data for this Ligand-Target Pair
Dihydroorotate dehydrogenase (quinone), mitochondrial (Homo sapiens (Human))	BDBM50397814 (CHEMBL2178511) Show SMILES Cc1cc(N)n2nc(SCc3ccc(Cl)c(Cl)c3)nc2n1 Show InChI InChI=1S/C13H11Cl2N5S/c1-7-4-11(16)20-12(17-7)18-13(19-20)21-6-8-2-3-9(14)10(15)5-8/h2-5H,6,16H2,1H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
University of Leeds Curated by ChEMBL					Assay Description Inhibition of human dihydroorate dehydrogenase expressed in Escherichia coli BL21(DE3) using dihydroorate as substrate by DCIP-based colorimetric ana...				J Med Chem 55: 5841-50 (2012) Article DOI: 10.1021/jm300157n BindingDB Entry DOI: 10.7270/Q2HT2QG8
					More data for this Ligand-Target Pair
Dihydroorotate dehydrogenase (quinone), mitochondrial (Homo sapiens (Human))	BDBM50397813 (CHEMBL2178512) Show SMILES Cc1cc(NCc2ccccc2)n2nc(SCc3ccccc3)nc2n1 Show InChI InChI=1S/C20H19N5S/c1-15-12-18(21-13-16-8-4-2-5-9-16)25-19(22-15)23-20(24-25)26-14-17-10-6-3-7-11-17/h2-12,21H,13-14H2,1H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
University of Leeds Curated by ChEMBL					Assay Description Inhibition of human dihydroorate dehydrogenase expressed in Escherichia coli BL21(DE3) using dihydroorate as substrate by DCIP-based colorimetric ana...				J Med Chem 55: 5841-50 (2012) Article DOI: 10.1021/jm300157n BindingDB Entry DOI: 10.7270/Q2HT2QG8
					More data for this Ligand-Target Pair