Compile Data Set for Download or QSAR

Found 415 hits with Last Name = 'ager' and Initial = 'i'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Protein kinase C theta type (Homo sapiens (Human))	BDBM50387328 (CHEMBL2046649) Show SMILES CC(C)C[C@H]1CN(CCN1)c1ccc(-c2ccccc2)c(n1)C(=O)c1cccnc1N |r| Show InChI InChI=1S/C25H29N5O/c1-17(2)15-19-16-30(14-13-27-19)22-11-10-20(18-7-4-3-5-8-18)23(29-22)24(31)21-9-6-12-28-25(21)26/h3-12,17,19,27H,13-16H2,1-2H3,(H2,26,28)/t19-/m0/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	0.600	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Department of Chemistry at Vertex Pharmaceuticals (Europe) Ltd Curated by ChEMBL					Assay Description Inhibition of PKCtheta				Bioorg Med Chem Lett 22: 4645-9 (2012) Article DOI: 10.1016/j.bmcl.2012.05.114 BindingDB Entry DOI: 10.7270/Q2TM7C65
					More data for this Ligand-Target Pair
Protein kinase C theta type (Homo sapiens (Human))	BDBM50387349 (CHEMBL2046644) Show SMILES CC(C)C[C@H]1CN(CCN1)c1ccc(Cl)c(n1)C(=O)c1cccnc1N |r| Show InChI InChI=1S/C19H24ClN5O/c1-12(2)10-13-11-25(9-8-22-13)16-6-5-15(20)17(24-16)18(26)14-4-3-7-23-19(14)21/h3-7,12-13,22H,8-11H2,1-2H3,(H2,21,23)/t13-/m0/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	2	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Department of Chemistry at Vertex Pharmaceuticals (Europe) Ltd Curated by ChEMBL					Assay Description Inhibition of PKCtheta				Bioorg Med Chem Lett 22: 4645-9 (2012) Article DOI: 10.1016/j.bmcl.2012.05.114 BindingDB Entry DOI: 10.7270/Q2TM7C65
					More data for this Ligand-Target Pair
Protein kinase C theta type (Homo sapiens (Human))	BDBM50387346 (CHEMBL2046640) Show SMILES CC(C)C[C@H]1CN(CCN1)c1cccc(n1)C(=O)c1cccnc1N |r| Show InChI InChI=1S/C19H25N5O/c1-13(2)11-14-12-24(10-9-21-14)17-7-3-6-16(23-17)18(25)15-5-4-8-22-19(15)20/h3-8,13-14,21H,9-12H2,1-2H3,(H2,20,22)/t14-/m0/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Department of Chemistry at Vertex Pharmaceuticals (Europe) Ltd Curated by ChEMBL					Assay Description Inhibition of PKCtheta				Bioorg Med Chem Lett 22: 4645-9 (2012) Article DOI: 10.1016/j.bmcl.2012.05.114 BindingDB Entry DOI: 10.7270/Q2TM7C65
					More data for this Ligand-Target Pair
Protein kinase C theta type (Homo sapiens (Human))	BDBM50387330 (CHEMBL2046643) Show SMILES CC(C)C[C@H]1CN(CCN1)c1ccc(c(n1)C(=O)c1cccnc1N)C(F)(F)F |r| Show InChI InChI=1S/C20H24F3N5O/c1-12(2)10-13-11-28(9-8-25-13)16-6-5-15(20(21,22)23)17(27-16)18(29)14-4-3-7-26-19(14)24/h3-7,12-13,25H,8-11H2,1-2H3,(H2,24,26)/t13-/m0/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Department of Chemistry at Vertex Pharmaceuticals (Europe) Ltd Curated by ChEMBL					Assay Description Inhibition of PKCtheta				Bioorg Med Chem Lett 22: 4645-9 (2012) Article DOI: 10.1016/j.bmcl.2012.05.114 BindingDB Entry DOI: 10.7270/Q2TM7C65
					More data for this Ligand-Target Pair
Protein kinase C theta type (Homo sapiens (Human))	BDBM50387343 (CHEMBL2046637) Show SMILES CC(C)[C@H]1CN(CCN1)c1cccc(n1)C(=O)c1cccnc1N |r| Show InChI InChI=1S/C18H23N5O/c1-12(2)15-11-23(10-9-20-15)16-7-3-6-14(22-16)17(24)13-5-4-8-21-18(13)19/h3-8,12,15,20H,9-11H2,1-2H3,(H2,19,21)/t15-/m1/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Department of Chemistry at Vertex Pharmaceuticals (Europe) Ltd Curated by ChEMBL					Assay Description Inhibition of PKCtheta				Bioorg Med Chem Lett 22: 4645-9 (2012) Article DOI: 10.1016/j.bmcl.2012.05.114 BindingDB Entry DOI: 10.7270/Q2TM7C65
					More data for this Ligand-Target Pair
Protein kinase C theta type (Homo sapiens (Human))	BDBM50387348 (CHEMBL2046642) Show SMILES Nc1ncccc1C(=O)c1cccc(n1)N1CCN[C@H](C1)c1ccccc1 |r| Show InChI InChI=1S/C21H21N5O/c22-21-16(8-5-11-24-21)20(27)17-9-4-10-19(25-17)26-13-12-23-18(14-26)15-6-2-1-3-7-15/h1-11,18,23H,12-14H2,(H2,22,24)/t18-/m1/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	6	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Department of Chemistry at Vertex Pharmaceuticals (Europe) Ltd Curated by ChEMBL					Assay Description Inhibition of PKCtheta				Bioorg Med Chem Lett 22: 4645-9 (2012) Article DOI: 10.1016/j.bmcl.2012.05.114 BindingDB Entry DOI: 10.7270/Q2TM7C65
					More data for this Ligand-Target Pair
Protein kinase C theta type (Homo sapiens (Human))	BDBM50387350 (CHEMBL2046646) Show SMILES CC(C)C[C@H]1CN(CCN1)c1ccc(OC(F)F)c(n1)C(=O)c1cccnc1N |r| Show InChI InChI=1S/C20H25F2N5O2/c1-12(2)10-13-11-27(9-8-24-13)16-6-5-15(29-20(21)22)17(26-16)18(28)14-4-3-7-25-19(14)23/h3-7,12-13,20,24H,8-11H2,1-2H3,(H2,23,25)/t13-/m0/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	7	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Department of Chemistry at Vertex Pharmaceuticals (Europe) Ltd Curated by ChEMBL					Assay Description Inhibition of PKCtheta				Bioorg Med Chem Lett 22: 4645-9 (2012) Article DOI: 10.1016/j.bmcl.2012.05.114 BindingDB Entry DOI: 10.7270/Q2TM7C65
					More data for this Ligand-Target Pair
Protein kinase C delta type (Homo sapiens (Human))	BDBM50387328 (CHEMBL2046649) Show SMILES CC(C)C[C@H]1CN(CCN1)c1ccc(-c2ccccc2)c(n1)C(=O)c1cccnc1N |r| Show InChI InChI=1S/C25H29N5O/c1-17(2)15-19-16-30(14-13-27-19)22-11-10-20(18-7-4-3-5-8-18)23(29-22)24(31)21-9-6-12-28-25(21)26/h3-12,17,19,27H,13-16H2,1-2H3,(H2,26,28)/t19-/m0/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	<10	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Department of Chemistry at Vertex Pharmaceuticals (Europe) Ltd Curated by ChEMBL					Assay Description Inhibition of PKCdelta				Bioorg Med Chem Lett 22: 4645-9 (2012) Article DOI: 10.1016/j.bmcl.2012.05.114 BindingDB Entry DOI: 10.7270/Q2TM7C65
					More data for this Ligand-Target Pair
Protein kinase C alpha type (Homo sapiens (Human))	BDBM50387328 (CHEMBL2046649) Show SMILES CC(C)C[C@H]1CN(CCN1)c1ccc(-c2ccccc2)c(n1)C(=O)c1cccnc1N |r| Show InChI InChI=1S/C25H29N5O/c1-17(2)15-19-16-30(14-13-27-19)22-11-10-20(18-7-4-3-5-8-18)23(29-22)24(31)21-9-6-12-28-25(21)26/h3-12,17,19,27H,13-16H2,1-2H3,(H2,26,28)/t19-/m0/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	10	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Department of Chemistry at Vertex Pharmaceuticals (Europe) Ltd Curated by ChEMBL					Assay Description Inhibition of PKCalpha				Bioorg Med Chem Lett 22: 4645-9 (2012) Article DOI: 10.1016/j.bmcl.2012.05.114 BindingDB Entry DOI: 10.7270/Q2TM7C65
					More data for this Ligand-Target Pair
Protein kinase C epsilon type (Homo sapiens (Human))	BDBM50387330 (CHEMBL2046643) Show SMILES CC(C)C[C@H]1CN(CCN1)c1ccc(c(n1)C(=O)c1cccnc1N)C(F)(F)F |r| Show InChI InChI=1S/C20H24F3N5O/c1-12(2)10-13-11-28(9-8-25-13)16-6-5-15(20(21,22)23)17(27-16)18(29)14-4-3-7-26-19(14)24/h3-7,12-13,25H,8-11H2,1-2H3,(H2,24,26)/t13-/m0/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	17	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Department of Chemistry at Vertex Pharmaceuticals (Europe) Ltd Curated by ChEMBL					Assay Description Inhibition of PKCepsilon				Bioorg Med Chem Lett 22: 4645-9 (2012) Article DOI: 10.1016/j.bmcl.2012.05.114 BindingDB Entry DOI: 10.7270/Q2TM7C65
					More data for this Ligand-Target Pair
Protein kinase C theta type (Homo sapiens (Human))	BDBM50387352 (CHEMBL2046648) Show SMILES CCCc1ccc(nc1C(=O)c1cccnc1N)N1CCN[C@@H](CC(C)C)C1 |r| Show InChI InChI=1S/C22H31N5O/c1-4-6-16-8-9-19(27-12-11-24-17(14-27)13-15(2)3)26-20(16)21(28)18-7-5-10-25-22(18)23/h5,7-10,15,17,24H,4,6,11-14H2,1-3H3,(H2,23,25)/t17-/m0/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	20	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Department of Chemistry at Vertex Pharmaceuticals (Europe) Ltd Curated by ChEMBL					Assay Description Inhibition of PKCtheta				Bioorg Med Chem Lett 22: 4645-9 (2012) Article DOI: 10.1016/j.bmcl.2012.05.114 BindingDB Entry DOI: 10.7270/Q2TM7C65
					More data for this Ligand-Target Pair
Protein kinase C delta type (Homo sapiens (Human))	BDBM50387346 (CHEMBL2046640) Show SMILES CC(C)C[C@H]1CN(CCN1)c1cccc(n1)C(=O)c1cccnc1N |r| Show InChI InChI=1S/C19H25N5O/c1-13(2)11-14-12-24(10-9-21-14)17-7-3-6-16(23-17)18(25)15-5-4-8-22-19(15)20/h3-8,13-14,21H,9-12H2,1-2H3,(H2,20,22)/t14-/m0/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	20	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Department of Chemistry at Vertex Pharmaceuticals (Europe) Ltd Curated by ChEMBL					Assay Description Inhibition of PKCdelta				Bioorg Med Chem Lett 22: 4645-9 (2012) Article DOI: 10.1016/j.bmcl.2012.05.114 BindingDB Entry DOI: 10.7270/Q2TM7C65
					More data for this Ligand-Target Pair
Protein kinase C delta type (Homo sapiens (Human))	BDBM50387349 (CHEMBL2046644) Show SMILES CC(C)C[C@H]1CN(CCN1)c1ccc(Cl)c(n1)C(=O)c1cccnc1N |r| Show InChI InChI=1S/C19H24ClN5O/c1-12(2)10-13-11-25(9-8-22-13)16-6-5-15(20)17(24-16)18(26)14-4-3-7-23-19(14)21/h3-7,12-13,22H,8-11H2,1-2H3,(H2,21,23)/t13-/m0/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	22	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Department of Chemistry at Vertex Pharmaceuticals (Europe) Ltd Curated by ChEMBL					Assay Description Inhibition of PKCdelta				Bioorg Med Chem Lett 22: 4645-9 (2012) Article DOI: 10.1016/j.bmcl.2012.05.114 BindingDB Entry DOI: 10.7270/Q2TM7C65
					More data for this Ligand-Target Pair
Protein kinase C theta type (Homo sapiens (Human))	BDBM50387354 (CHEMBL2046651) Show SMILES CC(C)C[C@H]1CN(CCN1)c1cc(C)cc(n1)C(=O)c1cccnc1N |r| Show InChI InChI=1S/C20H27N5O/c1-13(2)9-15-12-25(8-7-22-15)18-11-14(3)10-17(24-18)19(26)16-5-4-6-23-20(16)21/h4-6,10-11,13,15,22H,7-9,12H2,1-3H3,(H2,21,23)/t15-/m0/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	24	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Department of Chemistry at Vertex Pharmaceuticals (Europe) Ltd Curated by ChEMBL					Assay Description Inhibition of PKCtheta				Bioorg Med Chem Lett 22: 4645-9 (2012) Article DOI: 10.1016/j.bmcl.2012.05.114 BindingDB Entry DOI: 10.7270/Q2TM7C65
					More data for this Ligand-Target Pair
Protein kinase C theta type (Homo sapiens (Human))	BDBM50387329 (CHEMBL2046645) Show SMILES CC(C)C[C@H]1CN(CCN1)c1ccc(C2CC2)c(n1)C(=O)c1cccnc1N |r| Show InChI InChI=1S/C22H29N5O/c1-14(2)12-16-13-27(11-10-24-16)19-8-7-17(15-5-6-15)20(26-19)21(28)18-4-3-9-25-22(18)23/h3-4,7-9,14-16,24H,5-6,10-13H2,1-2H3,(H2,23,25)/t16-/m0/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	28	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Department of Chemistry at Vertex Pharmaceuticals (Europe) Ltd Curated by ChEMBL					Assay Description Inhibition of PKCtheta				Bioorg Med Chem Lett 22: 4645-9 (2012) Article DOI: 10.1016/j.bmcl.2012.05.114 BindingDB Entry DOI: 10.7270/Q2TM7C65
					More data for this Ligand-Target Pair
Protein kinase C delta type (Homo sapiens (Human))	BDBM50387352 (CHEMBL2046648) Show SMILES CCCc1ccc(nc1C(=O)c1cccnc1N)N1CCN[C@@H](CC(C)C)C1 |r| Show InChI InChI=1S/C22H31N5O/c1-4-6-16-8-9-19(27-12-11-24-17(14-27)13-15(2)3)26-20(16)21(28)18-7-5-10-25-22(18)23/h5,7-10,15,17,24H,4,6,11-14H2,1-3H3,(H2,23,25)/t17-/m0/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	30	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Department of Chemistry at Vertex Pharmaceuticals (Europe) Ltd Curated by ChEMBL					Assay Description Inhibition of PKCdelta				Bioorg Med Chem Lett 22: 4645-9 (2012) Article DOI: 10.1016/j.bmcl.2012.05.114 BindingDB Entry DOI: 10.7270/Q2TM7C65
					More data for this Ligand-Target Pair
Protein kinase C theta type (Homo sapiens (Human))	BDBM50387333 (CHEMBL2046626) Show SMILES Nc1ncccc1C(=O)c1cccc(n1)N1CCNCC1 Show InChI InChI=1S/C15H17N5O/c16-15-11(3-2-6-18-15)14(21)12-4-1-5-13(19-12)20-9-7-17-8-10-20/h1-6,17H,7-10H2,(H2,16,18)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	32	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Department of Chemistry at Vertex Pharmaceuticals (Europe) Ltd Curated by ChEMBL					Assay Description Inhibition of PKCtheta				Bioorg Med Chem Lett 22: 4645-9 (2012) Article DOI: 10.1016/j.bmcl.2012.05.114 BindingDB Entry DOI: 10.7270/Q2TM7C65
					More data for this Ligand-Target Pair
Protein kinase C delta type (Homo sapiens (Human))	BDBM50387330 (CHEMBL2046643) Show SMILES CC(C)C[C@H]1CN(CCN1)c1ccc(c(n1)C(=O)c1cccnc1N)C(F)(F)F |r| Show InChI InChI=1S/C20H24F3N5O/c1-12(2)10-13-11-28(9-8-25-13)16-6-5-15(20(21,22)23)17(27-16)18(29)14-4-3-7-26-19(14)24/h3-7,12-13,25H,8-11H2,1-2H3,(H2,24,26)/t13-/m0/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	37	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Department of Chemistry at Vertex Pharmaceuticals (Europe) Ltd Curated by ChEMBL					Assay Description Inhibition of PKCdelta				Bioorg Med Chem Lett 22: 4645-9 (2012) Article DOI: 10.1016/j.bmcl.2012.05.114 BindingDB Entry DOI: 10.7270/Q2TM7C65
					More data for this Ligand-Target Pair
Protein kinase C theta type (Homo sapiens (Human))	BDBM50387345 (CHEMBL2046639) Show SMILES CC(C)(C)[C@H]1CN(CCN1)c1cccc(n1)C(=O)c1cccnc1N |r| Show InChI InChI=1S/C19H25N5O/c1-19(2,3)15-12-24(11-10-21-15)16-8-4-7-14(23-16)17(25)13-6-5-9-22-18(13)20/h4-9,15,21H,10-12H2,1-3H3,(H2,20,22)/t15-/m1/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	38	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Department of Chemistry at Vertex Pharmaceuticals (Europe) Ltd Curated by ChEMBL					Assay Description Inhibition of PKCtheta				Bioorg Med Chem Lett 22: 4645-9 (2012) Article DOI: 10.1016/j.bmcl.2012.05.114 BindingDB Entry DOI: 10.7270/Q2TM7C65
					More data for this Ligand-Target Pair
Protein kinase C alpha type (Homo sapiens (Human))	BDBM50387349 (CHEMBL2046644) Show SMILES CC(C)C[C@H]1CN(CCN1)c1ccc(Cl)c(n1)C(=O)c1cccnc1N |r| Show InChI InChI=1S/C19H24ClN5O/c1-12(2)10-13-11-25(9-8-22-13)16-6-5-15(20)17(24-16)18(26)14-4-3-7-23-19(14)21/h3-7,12-13,22H,8-11H2,1-2H3,(H2,21,23)/t13-/m0/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	49	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Department of Chemistry at Vertex Pharmaceuticals (Europe) Ltd Curated by ChEMBL					Assay Description Inhibition of PKCalpha				Bioorg Med Chem Lett 22: 4645-9 (2012) Article DOI: 10.1016/j.bmcl.2012.05.114 BindingDB Entry DOI: 10.7270/Q2TM7C65
					More data for this Ligand-Target Pair
Protein kinase C alpha type (Homo sapiens (Human))	BDBM50387346 (CHEMBL2046640) Show SMILES CC(C)C[C@H]1CN(CCN1)c1cccc(n1)C(=O)c1cccnc1N |r| Show InChI InChI=1S/C19H25N5O/c1-13(2)11-14-12-24(10-9-21-14)17-7-3-6-16(23-17)18(25)15-5-4-8-22-19(15)20/h3-8,13-14,21H,9-12H2,1-2H3,(H2,20,22)/t14-/m0/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	54	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Department of Chemistry at Vertex Pharmaceuticals (Europe) Ltd Curated by ChEMBL					Assay Description Inhibition of PKCalpha				Bioorg Med Chem Lett 22: 4645-9 (2012) Article DOI: 10.1016/j.bmcl.2012.05.114 BindingDB Entry DOI: 10.7270/Q2TM7C65
					More data for this Ligand-Target Pair
Protein kinase C theta type (Homo sapiens (Human))	BDBM50387341 (CHEMBL2046635) Show SMILES C[C@H]1CN(CCN1)c1cccc(n1)C(=O)c1cccnc1N |r| Show InChI InChI=1S/C16H19N5O/c1-11-10-21(9-8-18-11)14-6-2-5-13(20-14)15(22)12-4-3-7-19-16(12)17/h2-7,11,18H,8-10H2,1H3,(H2,17,19)/t11-/m0/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	67	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Department of Chemistry at Vertex Pharmaceuticals (Europe) Ltd Curated by ChEMBL					Assay Description Inhibition of PKCtheta				Bioorg Med Chem Lett 22: 4645-9 (2012) Article DOI: 10.1016/j.bmcl.2012.05.114 BindingDB Entry DOI: 10.7270/Q2TM7C65
					More data for this Ligand-Target Pair
Protein kinase C alpha type (Homo sapiens (Human))	BDBM50387330 (CHEMBL2046643) Show SMILES CC(C)C[C@H]1CN(CCN1)c1ccc(c(n1)C(=O)c1cccnc1N)C(F)(F)F |r| Show InChI InChI=1S/C20H24F3N5O/c1-12(2)10-13-11-28(9-8-25-13)16-6-5-15(20(21,22)23)17(27-16)18(29)14-4-3-7-26-19(14)24/h3-7,12-13,25H,8-11H2,1-2H3,(H2,24,26)/t13-/m0/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	76	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Department of Chemistry at Vertex Pharmaceuticals (Europe) Ltd Curated by ChEMBL					Assay Description Inhibition of PKCalpha				Bioorg Med Chem Lett 22: 4645-9 (2012) Article DOI: 10.1016/j.bmcl.2012.05.114 BindingDB Entry DOI: 10.7270/Q2TM7C65
					More data for this Ligand-Target Pair
Protein kinase C theta type (Homo sapiens (Human))	BDBM50387336 (CHEMBL2046629) Show SMILES NC1CCN(CC1)c1cccc(n1)C(=O)c1cccnc1N Show InChI InChI=1S/C16H19N5O/c17-11-6-9-21(10-7-11)14-5-1-4-13(20-14)15(22)12-3-2-8-19-16(12)18/h1-5,8,11H,6-7,9-10,17H2,(H2,18,19)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	76	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Department of Chemistry at Vertex Pharmaceuticals (Europe) Ltd Curated by ChEMBL					Assay Description Inhibition of PKCtheta				Bioorg Med Chem Lett 22: 4645-9 (2012) Article DOI: 10.1016/j.bmcl.2012.05.114 BindingDB Entry DOI: 10.7270/Q2TM7C65
					More data for this Ligand-Target Pair
Protein kinase C theta type (Homo sapiens (Human))	BDBM50387342 (CHEMBL2046636) Show SMILES CC1(C)CN(CCN1)c1cccc(n1)C(=O)c1cccnc1N Show InChI InChI=1S/C17H21N5O/c1-17(2)11-22(10-9-20-17)14-7-3-6-13(21-14)15(23)12-5-4-8-19-16(12)18/h3-8,20H,9-11H2,1-2H3,(H2,18,19)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	85	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Department of Chemistry at Vertex Pharmaceuticals (Europe) Ltd Curated by ChEMBL					Assay Description Inhibition of PKCtheta				Bioorg Med Chem Lett 22: 4645-9 (2012) Article DOI: 10.1016/j.bmcl.2012.05.114 BindingDB Entry DOI: 10.7270/Q2TM7C65
					More data for this Ligand-Target Pair
Protein kinase C delta type (Homo sapiens (Human))	BDBM50387350 (CHEMBL2046646) Show SMILES CC(C)C[C@H]1CN(CCN1)c1ccc(OC(F)F)c(n1)C(=O)c1cccnc1N |r| Show InChI InChI=1S/C20H25F2N5O2/c1-12(2)10-13-11-27(9-8-24-13)16-6-5-15(29-20(21)22)17(26-16)18(28)14-4-3-7-25-19(14)23/h3-7,12-13,20,24H,8-11H2,1-2H3,(H2,23,25)/t13-/m0/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	87	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Department of Chemistry at Vertex Pharmaceuticals (Europe) Ltd Curated by ChEMBL					Assay Description Inhibition of PKCdelta				Bioorg Med Chem Lett 22: 4645-9 (2012) Article DOI: 10.1016/j.bmcl.2012.05.114 BindingDB Entry DOI: 10.7270/Q2TM7C65
					More data for this Ligand-Target Pair
Protein kinase C delta type (Homo sapiens (Human))	BDBM50387354 (CHEMBL2046651) Show SMILES CC(C)C[C@H]1CN(CCN1)c1cc(C)cc(n1)C(=O)c1cccnc1N |r| Show InChI InChI=1S/C20H27N5O/c1-13(2)9-15-12-25(8-7-22-15)18-11-14(3)10-17(24-18)19(26)16-5-4-6-23-20(16)21/h4-6,10-11,13,15,22H,7-9,12H2,1-3H3,(H2,21,23)/t15-/m0/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	116	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Department of Chemistry at Vertex Pharmaceuticals (Europe) Ltd Curated by ChEMBL					Assay Description Inhibition of PKCdelta				Bioorg Med Chem Lett 22: 4645-9 (2012) Article DOI: 10.1016/j.bmcl.2012.05.114 BindingDB Entry DOI: 10.7270/Q2TM7C65
					More data for this Ligand-Target Pair
Protein kinase C theta type (Homo sapiens (Human))	BDBM50387331 (CHEMBL2046624) Show SMILES Nc1ncccc1C(=O)c1cccc(n1)N1CCCNCC1 Show InChI InChI=1S/C16H19N5O/c17-16-12(4-2-8-19-16)15(22)13-5-1-6-14(20-13)21-10-3-7-18-9-11-21/h1-2,4-6,8,18H,3,7,9-11H2,(H2,17,19)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	164	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Department of Chemistry at Vertex Pharmaceuticals (Europe) Ltd Curated by ChEMBL					Assay Description Inhibition of PKCtheta				Bioorg Med Chem Lett 22: 4645-9 (2012) Article DOI: 10.1016/j.bmcl.2012.05.114 BindingDB Entry DOI: 10.7270/Q2TM7C65
					More data for this Ligand-Target Pair
Protein kinase C theta type (Homo sapiens (Human))	BDBM50387340 (CHEMBL2046634) Show SMILES C[C@@H]1CN(CCN1)c1cccc(n1)C(=O)c1cccnc1N |r| Show InChI InChI=1S/C16H19N5O/c1-11-10-21(9-8-18-11)14-6-2-5-13(20-14)15(22)12-4-3-7-19-16(12)17/h2-7,11,18H,8-10H2,1H3,(H2,17,19)/t11-/m1/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	182	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Department of Chemistry at Vertex Pharmaceuticals (Europe) Ltd Curated by ChEMBL					Assay Description Inhibition of PKCtheta				Bioorg Med Chem Lett 22: 4645-9 (2012) Article DOI: 10.1016/j.bmcl.2012.05.114 BindingDB Entry DOI: 10.7270/Q2TM7C65
					More data for this Ligand-Target Pair
Protein kinase C theta type (Homo sapiens (Human))	BDBM50387347 (CHEMBL2046641) Show SMILES Nc1ncccc1C(=O)c1cccc(n1)N1CCN[C@@H](C1)c1ccccc1 |r| Show InChI InChI=1S/C21H21N5O/c22-21-16(8-5-11-24-21)20(27)17-9-4-10-19(25-17)26-13-12-23-18(14-26)15-6-2-1-3-7-15/h1-11,18,23H,12-14H2,(H2,22,24)/t18-/m0/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	238	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Department of Chemistry at Vertex Pharmaceuticals (Europe) Ltd Curated by ChEMBL					Assay Description Inhibition of PKCtheta				Bioorg Med Chem Lett 22: 4645-9 (2012) Article DOI: 10.1016/j.bmcl.2012.05.114 BindingDB Entry DOI: 10.7270/Q2TM7C65
					More data for this Ligand-Target Pair
Protein kinase C delta type (Homo sapiens (Human))	BDBM50387329 (CHEMBL2046645) Show SMILES CC(C)C[C@H]1CN(CCN1)c1ccc(C2CC2)c(n1)C(=O)c1cccnc1N |r| Show InChI InChI=1S/C22H29N5O/c1-14(2)12-16-13-27(11-10-24-16)19-8-7-17(15-5-6-15)20(26-19)21(28)18-4-3-9-25-22(18)23/h3-4,7-9,14-16,24H,5-6,10-13H2,1-2H3,(H2,23,25)/t16-/m0/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	255	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Department of Chemistry at Vertex Pharmaceuticals (Europe) Ltd Curated by ChEMBL					Assay Description Inhibition of PKCdelta				Bioorg Med Chem Lett 22: 4645-9 (2012) Article DOI: 10.1016/j.bmcl.2012.05.114 BindingDB Entry DOI: 10.7270/Q2TM7C65
					More data for this Ligand-Target Pair
Protein kinase C beta type (Homo sapiens (Human))	BDBM50387330 (CHEMBL2046643) Show SMILES CC(C)C[C@H]1CN(CCN1)c1ccc(c(n1)C(=O)c1cccnc1N)C(F)(F)F |r| Show InChI InChI=1S/C20H24F3N5O/c1-12(2)10-13-11-28(9-8-25-13)16-6-5-15(20(21,22)23)17(27-16)18(29)14-4-3-7-26-19(14)24/h3-7,12-13,25H,8-11H2,1-2H3,(H2,24,26)/t13-/m0/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	260	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Department of Chemistry at Vertex Pharmaceuticals (Europe) Ltd Curated by ChEMBL					Assay Description Inhibition of PKCbeta				Bioorg Med Chem Lett 22: 4645-9 (2012) Article DOI: 10.1016/j.bmcl.2012.05.114 BindingDB Entry DOI: 10.7270/Q2TM7C65
					More data for this Ligand-Target Pair
Protein kinase C theta type (Homo sapiens (Human))	BDBM50387344 (CHEMBL2046638) Show SMILES CC(C)[C@@H]1CN(CCN1)c1cccc(n1)C(=O)c1cccnc1N |r| Show InChI InChI=1S/C18H23N5O/c1-12(2)15-11-23(10-9-20-15)16-7-3-6-14(22-16)17(24)13-5-4-8-21-18(13)19/h3-8,12,15,20H,9-11H2,1-2H3,(H2,19,21)/t15-/m0/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	275	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Department of Chemistry at Vertex Pharmaceuticals (Europe) Ltd Curated by ChEMBL					Assay Description Inhibition of PKCtheta				Bioorg Med Chem Lett 22: 4645-9 (2012) Article DOI: 10.1016/j.bmcl.2012.05.114 BindingDB Entry DOI: 10.7270/Q2TM7C65
					More data for this Ligand-Target Pair
Protein kinase C theta type (Homo sapiens (Human))	BDBM50387351 (CHEMBL2046647) Show SMILES CC(C)C[C@H]1CN(CCN1)c1ccc(OCC(F)(F)F)c(n1)C(=O)c1cccnc1N |r| Show InChI InChI=1S/C21H26F3N5O2/c1-13(2)10-14-11-29(9-8-26-14)17-6-5-16(31-12-21(22,23)24)18(28-17)19(30)15-4-3-7-27-20(15)25/h3-7,13-14,26H,8-12H2,1-2H3,(H2,25,27)/t14-/m0/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	290	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Department of Chemistry at Vertex Pharmaceuticals (Europe) Ltd Curated by ChEMBL					Assay Description Inhibition of PKCtheta				Bioorg Med Chem Lett 22: 4645-9 (2012) Article DOI: 10.1016/j.bmcl.2012.05.114 BindingDB Entry DOI: 10.7270/Q2TM7C65
					More data for this Ligand-Target Pair
Protein kinase C theta type (Homo sapiens (Human))	BDBM50387332 (CHEMBL2046625) Show SMILES CN1CCCN(CC1)c1cccc(n1)C(=O)c1cccnc1N Show InChI InChI=1S/C17H21N5O/c1-21-9-4-10-22(12-11-21)15-7-2-6-14(20-15)16(23)13-5-3-8-19-17(13)18/h2-3,5-8H,4,9-12H2,1H3,(H2,18,19)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	375	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Department of Chemistry at Vertex Pharmaceuticals (Europe) Ltd Curated by ChEMBL					Assay Description Inhibition of PKCtheta				Bioorg Med Chem Lett 22: 4645-9 (2012) Article DOI: 10.1016/j.bmcl.2012.05.114 BindingDB Entry DOI: 10.7270/Q2TM7C65
					More data for this Ligand-Target Pair
Protein kinase C alpha type (Homo sapiens (Human))	BDBM50387350 (CHEMBL2046646) Show SMILES CC(C)C[C@H]1CN(CCN1)c1ccc(OC(F)F)c(n1)C(=O)c1cccnc1N |r| Show InChI InChI=1S/C20H25F2N5O2/c1-12(2)10-13-11-27(9-8-24-13)16-6-5-15(29-20(21)22)17(26-16)18(28)14-4-3-7-25-19(14)23/h3-7,12-13,20,24H,8-11H2,1-2H3,(H2,23,25)/t13-/m0/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	459	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Department of Chemistry at Vertex Pharmaceuticals (Europe) Ltd Curated by ChEMBL					Assay Description Inhibition of PKCalpha				Bioorg Med Chem Lett 22: 4645-9 (2012) Article DOI: 10.1016/j.bmcl.2012.05.114 BindingDB Entry DOI: 10.7270/Q2TM7C65
					More data for this Ligand-Target Pair
Protein kinase C alpha type (Homo sapiens (Human))	BDBM50387354 (CHEMBL2046651) Show SMILES CC(C)C[C@H]1CN(CCN1)c1cc(C)cc(n1)C(=O)c1cccnc1N |r| Show InChI InChI=1S/C20H27N5O/c1-13(2)9-15-12-25(8-7-22-15)18-11-14(3)10-17(24-18)19(26)16-5-4-6-23-20(16)21/h4-6,10-11,13,15,22H,7-9,12H2,1-3H3,(H2,21,23)/t15-/m0/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	459	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Department of Chemistry at Vertex Pharmaceuticals (Europe) Ltd Curated by ChEMBL					Assay Description Inhibition of PKCalpha				Bioorg Med Chem Lett 22: 4645-9 (2012) Article DOI: 10.1016/j.bmcl.2012.05.114 BindingDB Entry DOI: 10.7270/Q2TM7C65
					More data for this Ligand-Target Pair
Receptor-type tyrosine-protein kinase FLT3 (Homo sapiens (Human))	BDBM50387330 (CHEMBL2046643) Show SMILES CC(C)C[C@H]1CN(CCN1)c1ccc(c(n1)C(=O)c1cccnc1N)C(F)(F)F |r| Show InChI InChI=1S/C20H24F3N5O/c1-12(2)10-13-11-28(9-8-25-13)16-6-5-15(20(21,22)23)17(27-16)18(29)14-4-3-7-26-19(14)24/h3-7,12-13,25H,8-11H2,1-2H3,(H2,24,26)/t13-/m0/s1	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	580	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Department of Chemistry at Vertex Pharmaceuticals (Europe) Ltd Curated by ChEMBL					Assay Description Inhibition of Flt3				Bioorg Med Chem Lett 22: 4645-9 (2012) Article DOI: 10.1016/j.bmcl.2012.05.114 BindingDB Entry DOI: 10.7270/Q2TM7C65
					More data for this Ligand-Target Pair
Protein kinase C theta type (Homo sapiens (Human))	BDBM50387353 (CHEMBL2046650) Show SMILES CC(C)C[C@H]1CN(CCN1)c1ccc(Cc2ccccc2)c(n1)C(=O)c1cccnc1N |r| Show InChI InChI=1S/C26H31N5O/c1-18(2)15-21-17-31(14-13-28-21)23-11-10-20(16-19-7-4-3-5-8-19)24(30-23)25(32)22-9-6-12-29-26(22)27/h3-12,18,21,28H,13-17H2,1-2H3,(H2,27,29)/t21-/m0/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	>700	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Department of Chemistry at Vertex Pharmaceuticals (Europe) Ltd Curated by ChEMBL					Assay Description Inhibition of PKCtheta				Bioorg Med Chem Lett 22: 4645-9 (2012) Article DOI: 10.1016/j.bmcl.2012.05.114 BindingDB Entry DOI: 10.7270/Q2TM7C65
					More data for this Ligand-Target Pair
Protein kinase C theta type (Homo sapiens (Human))	BDBM50387335 (CHEMBL2046628) Show SMILES NCC1CCN(C1)c1cccc(n1)C(=O)c1cccnc1N Show InChI InChI=1S/C16H19N5O/c17-9-11-6-8-21(10-11)14-5-1-4-13(20-14)15(22)12-3-2-7-19-16(12)18/h1-5,7,11H,6,8-10,17H2,(H2,18,19)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	745	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Department of Chemistry at Vertex Pharmaceuticals (Europe) Ltd Curated by ChEMBL					Assay Description Inhibition of PKCtheta				Bioorg Med Chem Lett 22: 4645-9 (2012) Article DOI: 10.1016/j.bmcl.2012.05.114 BindingDB Entry DOI: 10.7270/Q2TM7C65
					More data for this Ligand-Target Pair
Protein kinase C theta type (Homo sapiens (Human))	BDBM50387339 (CHEMBL2046633) Show SMILES NCC1CN(C1)c1cccc(n1)C(=O)c1cccnc1N Show InChI InChI=1S/C15H17N5O/c16-7-10-8-20(9-10)13-5-1-4-12(19-13)14(21)11-3-2-6-18-15(11)17/h1-6,10H,7-9,16H2,(H2,17,18)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.01E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Department of Chemistry at Vertex Pharmaceuticals (Europe) Ltd Curated by ChEMBL					Assay Description Inhibition of PKCtheta				Bioorg Med Chem Lett 22: 4645-9 (2012) Article DOI: 10.1016/j.bmcl.2012.05.114 BindingDB Entry DOI: 10.7270/Q2TM7C65
					More data for this Ligand-Target Pair
Protein kinase C alpha type (Homo sapiens (Human))	BDBM50387352 (CHEMBL2046648) Show SMILES CCCc1ccc(nc1C(=O)c1cccnc1N)N1CCN[C@@H](CC(C)C)C1 |r| Show InChI InChI=1S/C22H31N5O/c1-4-6-16-8-9-19(27-12-11-24-17(14-27)13-15(2)3)26-20(16)21(28)18-7-5-10-25-22(18)23/h5,7-10,15,17,24H,4,6,11-14H2,1-3H3,(H2,23,25)/t17-/m0/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.23E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Department of Chemistry at Vertex Pharmaceuticals (Europe) Ltd Curated by ChEMBL					Assay Description Inhibition of PKCalpha				Bioorg Med Chem Lett 22: 4645-9 (2012) Article DOI: 10.1016/j.bmcl.2012.05.114 BindingDB Entry DOI: 10.7270/Q2TM7C65
					More data for this Ligand-Target Pair
Protein kinase C alpha type (Homo sapiens (Human))	BDBM50387351 (CHEMBL2046647) Show SMILES CC(C)C[C@H]1CN(CCN1)c1ccc(OCC(F)(F)F)c(n1)C(=O)c1cccnc1N |r| Show InChI InChI=1S/C21H26F3N5O2/c1-13(2)10-14-11-29(9-8-26-14)17-6-5-16(31-12-21(22,23)24)18(28-17)19(30)15-4-3-7-27-20(15)25/h3-7,13-14,26H,8-12H2,1-2H3,(H2,25,27)/t14-/m0/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	>1.25E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Department of Chemistry at Vertex Pharmaceuticals (Europe) Ltd Curated by ChEMBL					Assay Description Inhibition of PKCalpha				Bioorg Med Chem Lett 22: 4645-9 (2012) Article DOI: 10.1016/j.bmcl.2012.05.114 BindingDB Entry DOI: 10.7270/Q2TM7C65
					More data for this Ligand-Target Pair
Protein kinase C alpha type (Homo sapiens (Human))	BDBM50387353 (CHEMBL2046650) Show SMILES CC(C)C[C@H]1CN(CCN1)c1ccc(Cc2ccccc2)c(n1)C(=O)c1cccnc1N |r| Show InChI InChI=1S/C26H31N5O/c1-18(2)15-21-17-31(14-13-28-21)23-11-10-20(16-19-7-4-3-5-8-19)24(30-23)25(32)22-9-6-12-29-26(22)27/h3-12,18,21,28H,13-17H2,1-2H3,(H2,27,29)/t21-/m0/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	>1.25E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Department of Chemistry at Vertex Pharmaceuticals (Europe) Ltd Curated by ChEMBL					Assay Description Inhibition of PKCalpha				Bioorg Med Chem Lett 22: 4645-9 (2012) Article DOI: 10.1016/j.bmcl.2012.05.114 BindingDB Entry DOI: 10.7270/Q2TM7C65
					More data for this Ligand-Target Pair
Protein kinase C delta type (Homo sapiens (Human))	BDBM50387351 (CHEMBL2046647) Show SMILES CC(C)C[C@H]1CN(CCN1)c1ccc(OCC(F)(F)F)c(n1)C(=O)c1cccnc1N |r| Show InChI InChI=1S/C21H26F3N5O2/c1-13(2)10-14-11-29(9-8-26-14)17-6-5-16(31-12-21(22,23)24)18(28-17)19(30)15-4-3-7-27-20(15)25/h3-7,13-14,26H,8-12H2,1-2H3,(H2,25,27)/t14-/m0/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.30E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Department of Chemistry at Vertex Pharmaceuticals (Europe) Ltd Curated by ChEMBL					Assay Description Inhibition of PKCdelta				Bioorg Med Chem Lett 22: 4645-9 (2012) Article DOI: 10.1016/j.bmcl.2012.05.114 BindingDB Entry DOI: 10.7270/Q2TM7C65
					More data for this Ligand-Target Pair
Protein kinase C theta type (Homo sapiens (Human))	BDBM50387337 (CHEMBL2046631) Show SMILES NCC1CCN(CC1)c1cccc(n1)C(=O)c1cccnc1N Show InChI InChI=1S/C17H21N5O/c18-11-12-6-9-22(10-7-12)15-5-1-4-14(21-15)16(23)13-3-2-8-20-17(13)19/h1-5,8,12H,6-7,9-11,18H2,(H2,19,20)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.39E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Department of Chemistry at Vertex Pharmaceuticals (Europe) Ltd Curated by ChEMBL					Assay Description Inhibition of PKCtheta				Bioorg Med Chem Lett 22: 4645-9 (2012) Article DOI: 10.1016/j.bmcl.2012.05.114 BindingDB Entry DOI: 10.7270/Q2TM7C65
					More data for this Ligand-Target Pair
Protein kinase C theta type (Homo sapiens (Human))	BDBM50387334 (CHEMBL2046627) Show SMILES NC1CCN(C1)c1cccc(n1)C(=O)c1cccnc1N Show InChI InChI=1S/C15H17N5O/c16-10-6-8-20(9-10)13-5-1-4-12(19-13)14(21)11-3-2-7-18-15(11)17/h1-5,7,10H,6,8-9,16H2,(H2,17,18)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.52E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Department of Chemistry at Vertex Pharmaceuticals (Europe) Ltd Curated by ChEMBL					Assay Description Inhibition of PKCtheta				Bioorg Med Chem Lett 22: 4645-9 (2012) Article DOI: 10.1016/j.bmcl.2012.05.114 BindingDB Entry DOI: 10.7270/Q2TM7C65
					More data for this Ligand-Target Pair
Protein kinase C theta type (Homo sapiens (Human))	BDBM50387327 (CHEMBL2046630) Show SMILES NC1CCCN(C1)c1cccc(n1)C(=O)c1cccnc1N Show InChI InChI=1S/C16H19N5O/c17-11-4-3-9-21(10-11)14-7-1-6-13(20-14)15(22)12-5-2-8-19-16(12)18/h1-2,5-8,11H,3-4,9-10,17H2,(H2,18,19)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.98E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Department of Chemistry at Vertex Pharmaceuticals (Europe) Ltd Curated by ChEMBL					Assay Description Inhibition of PKCtheta				Bioorg Med Chem Lett 22: 4645-9 (2012) Article DOI: 10.1016/j.bmcl.2012.05.114 BindingDB Entry DOI: 10.7270/Q2TM7C65
					More data for this Ligand-Target Pair
Protein kinase C delta type (Homo sapiens (Human))	BDBM50387353 (CHEMBL2046650) Show SMILES CC(C)C[C@H]1CN(CCN1)c1ccc(Cc2ccccc2)c(n1)C(=O)c1cccnc1N |r| Show InChI InChI=1S/C26H31N5O/c1-18(2)15-21-17-31(14-13-28-21)23-11-10-20(16-19-7-4-3-5-8-19)24(30-23)25(32)22-9-6-12-29-26(22)27/h3-12,18,21,28H,13-17H2,1-2H3,(H2,27,29)/t21-/m0/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	>2.00E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Department of Chemistry at Vertex Pharmaceuticals (Europe) Ltd Curated by ChEMBL					Assay Description Inhibition of PKCdelta				Bioorg Med Chem Lett 22: 4645-9 (2012) Article DOI: 10.1016/j.bmcl.2012.05.114 BindingDB Entry DOI: 10.7270/Q2TM7C65
					More data for this Ligand-Target Pair
Protein kinase C alpha type (Homo sapiens (Human))	BDBM50387329 (CHEMBL2046645) Show SMILES CC(C)C[C@H]1CN(CCN1)c1ccc(C2CC2)c(n1)C(=O)c1cccnc1N |r| Show InChI InChI=1S/C22H29N5O/c1-14(2)12-16-13-27(11-10-24-16)19-8-7-17(15-5-6-15)20(26-19)21(28)18-4-3-9-25-22(18)23/h3-4,7-9,14-16,24H,5-6,10-13H2,1-2H3,(H2,23,25)/t16-/m0/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	2.65E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Department of Chemistry at Vertex Pharmaceuticals (Europe) Ltd Curated by ChEMBL					Assay Description Inhibition of PKCalpha				Bioorg Med Chem Lett 22: 4645-9 (2012) Article DOI: 10.1016/j.bmcl.2012.05.114 BindingDB Entry DOI: 10.7270/Q2TM7C65
					More data for this Ligand-Target Pair

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