BindingDB PrimarySearch

Found 16 hits with Last Name = 'ahmed-belkacem' and Initial = 'a'
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Broad substrate specificity ATP-binding cassette transporter ABCG2 (Homo sapiens (Human))	BDBM50371107 (CHEMBL397235) Show SMILES Show InChI	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	350	n/a	n/a	n/a	n/a	n/a	n/a
UMR 5063 CNRS/Universit£ Joseph Fourier-Grenoble I Curated by ChEMBL					Assay Description Inhibition of ABCG2 expressed in HEK293 cells assessed as mitoxantrone-mediated efflux by flow cytometry				Bioorg Med Chem 15: 2892-7 (2007) Article DOI: 10.1016/j.bmc.2007.02.017 BindingDB Entry DOI: 10.7270/Q2N58N6T
					More data for this Ligand-Target Pair
Broad substrate specificity ATP-binding cassette transporter ABCG2 (Homo sapiens (Human))	BDBM50206310 (5-Methoxy-9-oxo-9,10-dihydro-acridine-4-carboxylic...) Show SMILES Show InChI	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	410	n/a	n/a	n/a	n/a	n/a	n/a
UMR 5063 CNRS/Universit£ Joseph Fourier-Grenoble I Curated by ChEMBL					Assay Description Inhibition of ABCG2 expressed in HEK293 cells assessed as mitoxantrone-mediated efflux by flow cytometry				Bioorg Med Chem 15: 2892-7 (2007) Article DOI: 10.1016/j.bmc.2007.02.017 BindingDB Entry DOI: 10.7270/Q2N58N6T
					More data for this Ligand-Target Pair
Broad substrate specificity ATP-binding cassette transporter ABCG2 (Homo sapiens (Human))	BDBM50371104 (CHEMBL243167) Show SMILES Show InChI	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	450	n/a	n/a	n/a	n/a	n/a	n/a
UMR 5063 CNRS/Universit£ Joseph Fourier-Grenoble I Curated by ChEMBL					Assay Description Inhibition of ABCG2 expressed in HEK293 cells assessed as mitoxantrone-mediated efflux by flow cytometry				Bioorg Med Chem 15: 2892-7 (2007) Article DOI: 10.1016/j.bmc.2007.02.017 BindingDB Entry DOI: 10.7270/Q2N58N6T
					More data for this Ligand-Target Pair
Broad substrate specificity ATP-binding cassette transporter ABCG2 (Homo sapiens (Human))	BDBM50371110 (CHEMBL243168) Show SMILES Show InChI	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	560	n/a	n/a	n/a	n/a	n/a	n/a
UMR 5063 CNRS/Universit£ Joseph Fourier-Grenoble I Curated by ChEMBL					Assay Description Inhibition of ABCG2 expressed in HEK293 cells assessed as mitoxantrone-mediated efflux by flow cytometry				Bioorg Med Chem 15: 2892-7 (2007) Article DOI: 10.1016/j.bmc.2007.02.017 BindingDB Entry DOI: 10.7270/Q2N58N6T
					More data for this Ligand-Target Pair
Broad substrate specificity ATP-binding cassette transporter ABCG2 (Homo sapiens (Human))	BDBM50370874 (CHEMBL221371) Show SMILES Show InChI	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	700	n/a	n/a	n/a	n/a	n/a	n/a
UMR 5086 CNRS/Universit£ Lyon 1 Curated by ChEMBL					Assay Description Inhibition of BCRP expressed in human HEK293 cells assessed as maximal mitoxantrone accumulation				J Med Chem 50: 1933-8 (2007) Article DOI: 10.1021/jm061450q BindingDB Entry DOI: 10.7270/Q21V5FRP
UMR 5086 CNRS/Universit£ Lyon 1 Curated by ChEMBL					More data for this Ligand-Target Pair
Broad substrate specificity ATP-binding cassette transporter ABCG2 (Homo sapiens (Human))	BDBM50371108 (CHEMBL242513) Show SMILES COc1cc(cc2[nH]c3ccccc3c(=O)c12)C(F)(F)F Show InChI	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	770	n/a	n/a	n/a	n/a	n/a	n/a
UMR 5063 CNRS/Universit£ Joseph Fourier-Grenoble I Curated by ChEMBL					Assay Description Inhibition of ABCG2 expressed in HEK293 cells assessed as mitoxantrone-mediated efflux by flow cytometry				Bioorg Med Chem 15: 2892-7 (2007) Article DOI: 10.1016/j.bmc.2007.02.017 BindingDB Entry DOI: 10.7270/Q2N58N6T
					More data for this Ligand-Target Pair
Broad substrate specificity ATP-binding cassette transporter ABCG2 (Homo sapiens (Human))	BDBM50371114 (CHEMBL243169) Show SMILES Show InChI	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.38E+3	n/a	n/a	n/a	n/a	n/a	n/a
UMR 5063 CNRS/Universit£ Joseph Fourier-Grenoble I Curated by ChEMBL					Assay Description Inhibition of ABCG2 expressed in HEK293 cells assessed as mitoxantrone-mediated efflux by flow cytometry				Bioorg Med Chem 15: 2892-7 (2007) Article DOI: 10.1016/j.bmc.2007.02.017 BindingDB Entry DOI: 10.7270/Q2N58N6T
					More data for this Ligand-Target Pair
Broad substrate specificity ATP-binding cassette transporter ABCG2 (Homo sapiens (Human))	BDBM50370873 (CHEMBL222265) Show SMILES Show InChI	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.50E+3	n/a	n/a	n/a	n/a	n/a	n/a
UMR 5086 CNRS/Universit£ Lyon 1 Curated by ChEMBL					Assay Description Inhibition of BCRP expressed in human HEK293 cells assessed as maximal mitoxantrone accumulation				J Med Chem 50: 1933-8 (2007) Article DOI: 10.1021/jm061450q BindingDB Entry DOI: 10.7270/Q21V5FRP
UMR 5086 CNRS/Universit£ Lyon 1 Curated by ChEMBL					More data for this Ligand-Target Pair
Broad substrate specificity ATP-binding cassette transporter ABCG2 (Homo sapiens (Human))	BDBM50371109 (CHEMBL388886 \| GNF-PF-2549) Show SMILES COc1ccc2[nH]c3ccccc3c(=O)c2c1 Show InChI	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	4.80E+3	n/a	n/a	n/a	n/a	n/a	n/a
UMR 5063 CNRS/Universit£ Joseph Fourier-Grenoble I Curated by ChEMBL					Assay Description Inhibition of ABCG2 expressed in HEK293 cells assessed as mitoxantrone-mediated efflux by flow cytometry				Bioorg Med Chem 15: 2892-7 (2007) Article DOI: 10.1016/j.bmc.2007.02.017 BindingDB Entry DOI: 10.7270/Q2N58N6T
					More data for this Ligand-Target Pair
Broad substrate specificity ATP-binding cassette transporter ABCG2 (Homo sapiens (Human))	BDBM50371106 (CHEMBL243813) Show SMILES COc1cccc2[nH]c3ccccc3c(=O)c12 Show InChI	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	6.30E+3	n/a	n/a	n/a	n/a	n/a	n/a
UMR 5063 CNRS/Universit£ Joseph Fourier-Grenoble I Curated by ChEMBL					Assay Description Inhibition of ABCG2 expressed in HEK293 cells assessed as mitoxantrone-mediated efflux by flow cytometry				Bioorg Med Chem 15: 2892-7 (2007) Article DOI: 10.1016/j.bmc.2007.02.017 BindingDB Entry DOI: 10.7270/Q2N58N6T
					More data for this Ligand-Target Pair
Broad substrate specificity ATP-binding cassette transporter ABCG2 (Homo sapiens (Human))	BDBM50371105 (CHEMBL243814) Show SMILES COc1cc(OC)c2c(c1)[nH]c1ccccc1c2=O Show InChI	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	7.90E+3	n/a	n/a	n/a	n/a	n/a	n/a
UMR 5063 CNRS/Universit£ Joseph Fourier-Grenoble I Curated by ChEMBL					Assay Description Inhibition of ABCG2 expressed in HEK293 cells assessed as mitoxantrone-mediated efflux by flow cytometry				Bioorg Med Chem 15: 2892-7 (2007) Article DOI: 10.1016/j.bmc.2007.02.017 BindingDB Entry DOI: 10.7270/Q2N58N6T
					More data for this Ligand-Target Pair
Broad substrate specificity ATP-binding cassette transporter ABCG2 (Homo sapiens (Human))	BDBM50371111 (CHEMBL397685) Show SMILES Oc1cccc2[nH]c3ccccc3c(=O)c12 Show InChI	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>2.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
UMR 5063 CNRS/Universit£ Joseph Fourier-Grenoble I Curated by ChEMBL					Assay Description Inhibition of ABCG2 expressed in HEK293 cells assessed as mitoxantrone-mediated efflux by flow cytometry				Bioorg Med Chem 15: 2892-7 (2007) Article DOI: 10.1016/j.bmc.2007.02.017 BindingDB Entry DOI: 10.7270/Q2N58N6T
					More data for this Ligand-Target Pair
Broad substrate specificity ATP-binding cassette transporter ABCG2 (Homo sapiens (Human))	BDBM50371112 (CHEMBL242943) Show SMILES Oc1cc(cc2[nH]c3ccccc3c(=O)c12)C(F)(F)F Show InChI	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>2.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
UMR 5063 CNRS/Universit£ Joseph Fourier-Grenoble I Curated by ChEMBL					Assay Description Inhibition of ABCG2 expressed in HEK293 cells assessed as mitoxantrone-mediated efflux by flow cytometry				Bioorg Med Chem 15: 2892-7 (2007) Article DOI: 10.1016/j.bmc.2007.02.017 BindingDB Entry DOI: 10.7270/Q2N58N6T
					More data for this Ligand-Target Pair
Broad substrate specificity ATP-binding cassette transporter ABCG2 (Homo sapiens (Human))	BDBM60916 (2-hydroxy-10H-acridin-9-one \| 2-oxidanyl-10H-acrid...) Show SMILES Oc1ccc2[nH]c3ccccc3c(=O)c2c1 Show InChI	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>2.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
UMR 5063 CNRS/Universit£ Joseph Fourier-Grenoble I Curated by ChEMBL					Assay Description Inhibition of ABCG2 expressed in HEK293 cells assessed as mitoxantrone-mediated efflux by flow cytometry				Bioorg Med Chem 15: 2892-7 (2007) Article DOI: 10.1016/j.bmc.2007.02.017 BindingDB Entry DOI: 10.7270/Q2N58N6T
					More data for this Ligand-Target Pair
Broad substrate specificity ATP-binding cassette transporter ABCG2 (Homo sapiens (Human))	BDBM50371113 (CHEMBL242512) Show SMILES COc1ccc2[nH]c3ccccc3c(=O)c2c1OC Show InChI	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>2.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
UMR 5063 CNRS/Universit£ Joseph Fourier-Grenoble I Curated by ChEMBL					Assay Description Inhibition of ABCG2 expressed in HEK293 cells assessed as mitoxantrone-mediated efflux by flow cytometry				Bioorg Med Chem 15: 2892-7 (2007) Article DOI: 10.1016/j.bmc.2007.02.017 BindingDB Entry DOI: 10.7270/Q2N58N6T
					More data for this Ligand-Target Pair
Broad substrate specificity ATP-binding cassette transporter ABCG2 (Homo sapiens (Human))	BDBM50371103 (CHEMBL242942) Show SMILES COc1cc(O)c2c(c1)[nH]c1ccccc1c2=O Show InChI	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>2.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
UMR 5063 CNRS/Universit£ Joseph Fourier-Grenoble I Curated by ChEMBL					Assay Description Inhibition of ABCG2 expressed in HEK293 cells assessed as mitoxantrone-mediated efflux by flow cytometry				Bioorg Med Chem 15: 2892-7 (2007) Article DOI: 10.1016/j.bmc.2007.02.017 BindingDB Entry DOI: 10.7270/Q2N58N6T
					More data for this Ligand-Target Pair