Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Sodium-dependent serotonin transporter (Rattus norvegicus (rat)) | BDBM50346446 (4-[4-(3-benzo[b]thiophen-3-yl-3-hydroxypropylamino...) | PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 3.66E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Navarra Curated by ChEMBL | Assay Description Displacement of [3H]5-HT from of SERT in rat midbrain homogenates after 5 mins by scintillation counting | J Med Chem 54: 3086-90 (2011) Article DOI: 10.1021/jm2000773 BindingDB Entry DOI: 10.7270/Q26T0N0M | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sodium-dependent serotonin transporter (Rattus norvegicus (rat)) | BDBM50346445 (1-Benzo[b]thiophen-3-yl-3-[1-(4-nitro-2-trifluorom...) | PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem | Article PubMed | n/a | n/a | 7.02E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Navarra Curated by ChEMBL | Assay Description Displacement of [3H]5-HT from of SERT in rat midbrain homogenates after 5 mins by scintillation counting | J Med Chem 54: 3086-90 (2011) Article DOI: 10.1021/jm2000773 BindingDB Entry DOI: 10.7270/Q26T0N0M | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sodium-dependent serotonin transporter (Rattus norvegicus (rat)) | BDBM30130 (CHEMBL1201082 | CHEMBL41 | Fluoxetin | Fluoxetine ...) | PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL DrugBank MCE PC cid PC sid PDB UniChem Patents Similars | Article PubMed | n/a | n/a | 8.30E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Navarra Curated by ChEMBL | Assay Description Displacement of [3H]5-HT from of SERT in rat midbrain homogenates after 5 mins by scintillation counting | J Med Chem 54: 3086-90 (2011) Article DOI: 10.1021/jm2000773 BindingDB Entry DOI: 10.7270/Q26T0N0M | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sodium-dependent serotonin transporter (Rattus norvegicus (rat)) | BDBM50346447 (4-[4-(3-benzo[b]thiophen-3-yl-3-hydroxypropyl)-[1,...) | PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 5.78E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Navarra Curated by ChEMBL | Assay Description Displacement of [3H]5-HT from of SERT in rat midbrain homogenates after 5 mins by scintillation counting | J Med Chem 54: 3086-90 (2011) Article DOI: 10.1021/jm2000773 BindingDB Entry DOI: 10.7270/Q26T0N0M | |||||||||||
More data for this Ligand-Target Pair |