Compile Data Set for Download or QSAR

Found 30 hits with Last Name = 'aktas' and Initial = 'bh'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Eukaryotic translation initiation factor 4E (Homo sapiens (Human))	BDBM50018903 (CHEMBL3287126) Show SMILES COc1cc2CCc3sc(N\N=C(/Cc4ccccc4[N+]([O-])=O)C(O)=O)nc3-c2cc1OC Show InChI InChI=1S/C22H20N4O6S/c1-31-17-10-12-7-8-19-20(14(12)11-18(17)32-2)23-22(33-19)25-24-15(21(27)28)9-13-5-3-4-6-16(13)26(29)30/h3-6,10-11H,7-9H2,1-2H3,(H,23,25)(H,27,28)/b24-15+	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.05E+4	n/a	n/a	n/a	n/a	n/a	n/a
Harvard Medical School Curated by ChEMBL					Assay Description Displacement of N-alpha-fluorescein tagged eIF4G-derived peptide from GST-DN26-eIF4E (unknown origin) by fluorescence polarization assay				J Med Chem 57: 5094-111 (2014) Article DOI: 10.1021/jm401733v BindingDB Entry DOI: 10.7270/Q2251KR7
					More data for this Ligand-Target Pair
Eukaryotic translation initiation factor 4E (Homo sapiens (Human))	BDBM50018904 (CHEMBL3287130) Show SMILES COc1cc2OCc3sc(N\N=C(/Cc4ccccc4[N+]([O-])=O)C(O)=O)nc3-c2cc1OC Show InChI InChI=1S/C21H18N4O7S/c1-30-16-8-12-15(9-17(16)31-2)32-10-18-19(12)22-21(33-18)24-23-13(20(26)27)7-11-5-3-4-6-14(11)25(28)29/h3-6,8-9H,7,10H2,1-2H3,(H,22,24)(H,26,27)/b23-13+	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.05E+4	n/a	n/a	n/a	n/a	n/a	n/a
Harvard Medical School Curated by ChEMBL					Assay Description Displacement of N-alpha-fluorescein tagged eIF4G-derived peptide from GST-DN26-eIF4E (unknown origin) by fluorescence polarization assay				J Med Chem 57: 5094-111 (2014) Article DOI: 10.1021/jm401733v BindingDB Entry DOI: 10.7270/Q2251KR7
					More data for this Ligand-Target Pair
Eukaryotic translation initiation factor 4E (Homo sapiens (Human))	BDBM50018906 (CHEMBL3287117) Show SMILES OC(=O)C(\Cc1ccccc1[N+]([O-])=O)=N/Nc1nc-2c(CSc3c(Cl)c(Cl)ccc-23)s1 Show InChI InChI=1S/C19H12Cl2N4O4S2/c20-11-6-5-10-16-14(8-30-17(10)15(11)21)31-19(22-16)24-23-12(18(26)27)7-9-3-1-2-4-13(9)25(28)29/h1-6H,7-8H2,(H,22,24)(H,26,27)/b23-12-	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.15E+4	n/a	n/a	n/a	n/a	n/a	n/a
Harvard Medical School Curated by ChEMBL					Assay Description Displacement of N-alpha-fluorescein tagged eIF4G-derived peptide from GST-DN26-eIF4E (unknown origin) by fluorescence polarization assay				J Med Chem 57: 5094-111 (2014) Article DOI: 10.1021/jm401733v BindingDB Entry DOI: 10.7270/Q2251KR7
					More data for this Ligand-Target Pair
Eukaryotic translation initiation factor 4E (Homo sapiens (Human))	BDBM50018902 (CHEMBL3287115) Show SMILES OC(=O)C(\Cc1ccccc1[N+]([O-])=O)=N/Nc1nc-2c(CSc3cc(Cl)c(Cl)cc-23)s1 Show InChI InChI=1S/C19H12Cl2N4O4S2/c20-11-6-10-15(7-12(11)21)30-8-16-17(10)22-19(31-16)24-23-13(18(26)27)5-9-3-1-2-4-14(9)25(28)29/h1-4,6-7H,5,8H2,(H,22,24)(H,26,27)/b23-13-	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.40E+4	n/a	n/a	n/a	n/a	n/a	n/a
Harvard Medical School Curated by ChEMBL					Assay Description Displacement of N-alpha-fluorescein tagged eIF4G-derived peptide from GST-DN26-eIF4E (unknown origin) by fluorescence polarization assay				J Med Chem 57: 5094-111 (2014) Article DOI: 10.1021/jm401733v BindingDB Entry DOI: 10.7270/Q2251KR7
					More data for this Ligand-Target Pair
Eukaryotic translation initiation factor 4E (Homo sapiens (Human))	BDBM50018907 (CHEMBL3287111) Show SMILES OC(=O)C(\Cc1ccccc1[N+]([O-])=O)=N/Nc1nc-2c(COc3c(Cl)c(Cl)ccc-23)s1 Show InChI InChI=1S/C19H12Cl2N4O5S/c20-11-6-5-10-16-14(8-30-17(10)15(11)21)31-19(22-16)24-23-12(18(26)27)7-9-3-1-2-4-13(9)25(28)29/h1-6H,7-8H2,(H,22,24)(H,26,27)/b23-12-	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.55E+4	n/a	n/a	n/a	n/a	n/a	n/a
Harvard Medical School Curated by ChEMBL					Assay Description Displacement of N-alpha-fluorescein tagged eIF4G-derived peptide from GST-DN26-eIF4E (unknown origin) by fluorescence polarization assay				J Med Chem 57: 5094-111 (2014) Article DOI: 10.1021/jm401733v BindingDB Entry DOI: 10.7270/Q2251KR7
					More data for this Ligand-Target Pair
Eukaryotic translation initiation factor 4E (Homo sapiens (Human))	BDBM50018908 (CHEMBL3287114) Show SMILES OC(=O)C(\Cc1ccccc1[N+]([O-])=O)=N\Nc1nc-2c(CSc3cc(Cl)c(Cl)cc-23)s1 Show InChI InChI=1S/C19H12Cl2N4O4S2/c20-11-6-10-15(7-12(11)21)30-8-16-17(10)22-19(31-16)24-23-13(18(26)27)5-9-3-1-2-4-14(9)25(28)29/h1-4,6-7H,5,8H2,(H,22,24)(H,26,27)/b23-13+	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.55E+4	n/a	n/a	n/a	n/a	n/a	n/a
Harvard Medical School Curated by ChEMBL					Assay Description Displacement of N-alpha-fluorescein tagged eIF4G-derived peptide from GST-DN26-eIF4E (unknown origin) by fluorescence polarization assay				J Med Chem 57: 5094-111 (2014) Article DOI: 10.1021/jm401733v BindingDB Entry DOI: 10.7270/Q2251KR7
					More data for this Ligand-Target Pair
Eukaryotic translation initiation factor 4E (Homo sapiens (Human))	BDBM50018926 (CHEMBL3287128) Show SMILES COc1ccc2-c3nc(N\N=C(/Cc4ccccc4[N+]([O-])=O)C(O)=O)sc3COc2c1OC Show InChI InChI=1S/C21H18N4O7S/c1-30-15-8-7-12-17-16(10-32-18(12)19(15)31-2)33-21(22-17)24-23-13(20(26)27)9-11-5-3-4-6-14(11)25(28)29/h3-8H,9-10H2,1-2H3,(H,22,24)(H,26,27)/b23-13+	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.65E+4	n/a	n/a	n/a	n/a	n/a	n/a
Harvard Medical School Curated by ChEMBL					Assay Description Displacement of N-alpha-fluorescein tagged eIF4G-derived peptide from GST-DN26-eIF4E (unknown origin) by fluorescence polarization assay				J Med Chem 57: 5094-111 (2014) Article DOI: 10.1021/jm401733v BindingDB Entry DOI: 10.7270/Q2251KR7
					More data for this Ligand-Target Pair
Eukaryotic translation initiation factor 4E (Homo sapiens (Human))	BDBM50018909 (CHEMBL3287112) Show SMILES OC(=O)C(\Cc1ccccc1[N+]([O-])=O)=N\Nc1nc-2c(COc3cc(Cl)c(Cl)cc-23)s1 Show InChI InChI=1S/C19H12Cl2N4O5S/c20-11-6-10-15(7-12(11)21)30-8-16-17(10)22-19(31-16)24-23-13(18(26)27)5-9-3-1-2-4-14(9)25(28)29/h1-4,6-7H,5,8H2,(H,22,24)(H,26,27)/b23-13+	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.85E+4	n/a	n/a	n/a	n/a	n/a	n/a
Harvard Medical School Curated by ChEMBL					Assay Description Displacement of N-alpha-fluorescein tagged eIF4G-derived peptide from GST-DN26-eIF4E (unknown origin) by fluorescence polarization assay				J Med Chem 57: 5094-111 (2014) Article DOI: 10.1021/jm401733v BindingDB Entry DOI: 10.7270/Q2251KR7
					More data for this Ligand-Target Pair
Eukaryotic translation initiation factor 4E (Homo sapiens (Human))	BDBM50018910 (CHEMBL3287106) Show SMILES OC(=O)C(\Cc1ccccc1[N+]([O-])=O)=N\Nc1nc-2c(CCc3cc(Cl)c(Cl)cc-23)s1 Show InChI InChI=1S/C20H14Cl2N4O4S/c21-13-7-10-5-6-17-18(12(10)9-14(13)22)23-20(31-17)25-24-15(19(27)28)8-11-3-1-2-4-16(11)26(29)30/h1-4,7,9H,5-6,8H2,(H,23,25)(H,27,28)/b24-15+	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.15E+4	n/a	n/a	n/a	n/a	n/a	n/a
Harvard Medical School Curated by ChEMBL					Assay Description Displacement of N-alpha-fluorescein tagged eIF4G-derived peptide from GST-DN26-eIF4E (unknown origin) by fluorescence polarization assay				J Med Chem 57: 5094-111 (2014) Article DOI: 10.1021/jm401733v BindingDB Entry DOI: 10.7270/Q2251KR7
					More data for this Ligand-Target Pair
Eukaryotic translation initiation factor 4E (Homo sapiens (Human))	BDBM50018911 (CHEMBL3287110) Show SMILES OC(=O)C(\Cc1ccccc1[N+]([O-])=O)=N\Nc1nc-2c(COc3c(Cl)c(Cl)ccc-23)s1 Show InChI InChI=1S/C19H12Cl2N4O5S/c20-11-6-5-10-16-14(8-30-17(10)15(11)21)31-19(22-16)24-23-12(18(26)27)7-9-3-1-2-4-13(9)25(28)29/h1-6H,7-8H2,(H,22,24)(H,26,27)/b23-12+	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.50E+4	n/a	n/a	n/a	n/a	n/a	n/a
Harvard Medical School Curated by ChEMBL					Assay Description Displacement of N-alpha-fluorescein tagged eIF4G-derived peptide from GST-DN26-eIF4E (unknown origin) by fluorescence polarization assay				J Med Chem 57: 5094-111 (2014) Article DOI: 10.1021/jm401733v BindingDB Entry DOI: 10.7270/Q2251KR7
					More data for this Ligand-Target Pair
Eukaryotic translation initiation factor 4E (Homo sapiens (Human))	BDBM50018913 (CHEMBL3287113) Show SMILES OC(=O)C(\Cc1ccccc1[N+]([O-])=O)=N/Nc1nc-2c(COc3cc(Cl)c(Cl)cc-23)s1 Show InChI InChI=1S/C19H12Cl2N4O5S/c20-11-6-10-15(7-12(11)21)30-8-16-17(10)22-19(31-16)24-23-13(18(26)27)5-9-3-1-2-4-14(9)25(28)29/h1-4,6-7H,5,8H2,(H,22,24)(H,26,27)/b23-13-	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.70E+4	n/a	n/a	n/a	n/a	n/a	n/a
Harvard Medical School Curated by ChEMBL					Assay Description Displacement of N-alpha-fluorescein tagged eIF4G-derived peptide from GST-DN26-eIF4E (unknown origin) by fluorescence polarization assay				J Med Chem 57: 5094-111 (2014) Article DOI: 10.1021/jm401733v BindingDB Entry DOI: 10.7270/Q2251KR7
					More data for this Ligand-Target Pair
Eukaryotic translation initiation factor 4E (Homo sapiens (Human))	BDBM50018916 (CHEMBL3287116) Show SMILES OC(=O)C(\Cc1ccccc1[N+]([O-])=O)=N\Nc1nc-2c(CSc3c(Cl)c(Cl)ccc-23)s1 Show InChI InChI=1S/C19H12Cl2N4O4S2/c20-11-6-5-10-16-14(8-30-17(10)15(11)21)31-19(22-16)24-23-12(18(26)27)7-9-3-1-2-4-13(9)25(28)29/h1-6H,7-8H2,(H,22,24)(H,26,27)/b23-12+	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.80E+4	n/a	n/a	n/a	n/a	n/a	n/a
Harvard Medical School Curated by ChEMBL					Assay Description Displacement of N-alpha-fluorescein tagged eIF4G-derived peptide from GST-DN26-eIF4E (unknown origin) by fluorescence polarization assay				J Med Chem 57: 5094-111 (2014) Article DOI: 10.1021/jm401733v BindingDB Entry DOI: 10.7270/Q2251KR7
					More data for this Ligand-Target Pair
Eukaryotic translation initiation factor 4E (Homo sapiens (Human))	BDBM50018917 (CHEMBL3287119) Show SMILES OC(=O)C(\Cc1ccccc1[N+]([O-])=O)=N/Nc1nc-2c(C[S+]([O-])c3cc(Cl)c(Cl)cc-23)s1 Show InChI InChI=1S/C19H12Cl2N4O5S2/c20-11-6-10-16(7-12(11)21)32(30)8-15-17(10)22-19(31-15)24-23-13(18(26)27)5-9-3-1-2-4-14(9)25(28)29/h1-4,6-7H,5,8H2,(H,22,24)(H,26,27)/b23-13-	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Harvard Medical School Curated by ChEMBL					Assay Description Displacement of N-alpha-fluorescein tagged eIF4G-derived peptide from GST-DN26-eIF4E (unknown origin) by fluorescence polarization assay				J Med Chem 57: 5094-111 (2014) Article DOI: 10.1021/jm401733v BindingDB Entry DOI: 10.7270/Q2251KR7
					More data for this Ligand-Target Pair
Eukaryotic translation initiation factor 4E (Homo sapiens (Human))	BDBM50018920 (CHEMBL3287118) Show SMILES OC(=O)C(\Cc1ccccc1[N+]([O-])=O)=N\Nc1nc-2c(C[S+]([O-])c3cc(Cl)c(Cl)cc-23)s1 Show InChI InChI=1S/C19H12Cl2N4O5S2/c20-11-6-10-16(7-12(11)21)32(30)8-15-17(10)22-19(31-15)24-23-13(18(26)27)5-9-3-1-2-4-14(9)25(28)29/h1-4,6-7H,5,8H2,(H,22,24)(H,26,27)/b23-13+	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.05E+4	n/a	n/a	n/a	n/a	n/a	n/a
Harvard Medical School Curated by ChEMBL					Assay Description Displacement of N-alpha-fluorescein tagged eIF4G-derived peptide from GST-DN26-eIF4E (unknown origin) by fluorescence polarization assay				J Med Chem 57: 5094-111 (2014) Article DOI: 10.1021/jm401733v BindingDB Entry DOI: 10.7270/Q2251KR7
					More data for this Ligand-Target Pair
Eukaryotic translation initiation factor 4E (Homo sapiens (Human))	BDBM50018918 (CHEMBL3287108) Show SMILES OC(=O)C(\Cc1ccccc1[N+]([O-])=O)=N\Nc1nc-2c(CCc3c(Cl)c(Cl)ccc-23)s1 Show InChI InChI=1S/C20H14Cl2N4O4S/c21-13-7-5-12-11(17(13)22)6-8-16-18(12)23-20(31-16)25-24-14(19(27)28)9-10-3-1-2-4-15(10)26(29)30/h1-5,7H,6,8-9H2,(H,23,25)(H,27,28)/b24-14+	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.20E+4	n/a	n/a	n/a	n/a	n/a	n/a
Harvard Medical School Curated by ChEMBL					Assay Description Displacement of N-alpha-fluorescein tagged eIF4G-derived peptide from GST-DN26-eIF4E (unknown origin) by fluorescence polarization assay				J Med Chem 57: 5094-111 (2014) Article DOI: 10.1021/jm401733v BindingDB Entry DOI: 10.7270/Q2251KR7
					More data for this Ligand-Target Pair
Eukaryotic translation initiation factor 4E (Homo sapiens (Human))	BDBM50018921 (CHEMBL3287121) Show SMILES OC(=O)C(\Cc1ccccc1[N+]([O-])=O)=N/Nc1nc-2c(C[S+]([O-])c3c(Cl)c(Cl)ccc-23)s1 Show InChI InChI=1S/C19H12Cl2N4O5S2/c20-11-6-5-10-16-14(8-32(30)17(10)15(11)21)31-19(22-16)24-23-12(18(26)27)7-9-3-1-2-4-13(9)25(28)29/h1-6H,7-8H2,(H,22,24)(H,26,27)/b23-12-	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.25E+4	n/a	n/a	n/a	n/a	n/a	n/a
Harvard Medical School Curated by ChEMBL					Assay Description Displacement of N-alpha-fluorescein tagged eIF4G-derived peptide from GST-DN26-eIF4E (unknown origin) by fluorescence polarization assay				J Med Chem 57: 5094-111 (2014) Article DOI: 10.1021/jm401733v BindingDB Entry DOI: 10.7270/Q2251KR7
					More data for this Ligand-Target Pair
Eukaryotic translation initiation factor 4E (Homo sapiens (Human))	BDBM50018927 (CHEMBL3287107) Show SMILES OC(=O)C(\Cc1ccccc1[N+]([O-])=O)=N/Nc1nc-2c(CCc3cc(Cl)c(Cl)cc-23)s1 Show InChI InChI=1S/C20H14Cl2N4O4S/c21-13-7-10-5-6-17-18(12(10)9-14(13)22)23-20(31-17)25-24-15(19(27)28)8-11-3-1-2-4-16(11)26(29)30/h1-4,7,9H,5-6,8H2,(H,23,25)(H,27,28)/b24-15-	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.40E+4	n/a	n/a	n/a	n/a	n/a	n/a
Harvard Medical School Curated by ChEMBL					Assay Description Displacement of N-alpha-fluorescein tagged eIF4G-derived peptide from GST-DN26-eIF4E (unknown origin) by fluorescence polarization assay				J Med Chem 57: 5094-111 (2014) Article DOI: 10.1021/jm401733v BindingDB Entry DOI: 10.7270/Q2251KR7
					More data for this Ligand-Target Pair
Eukaryotic translation initiation factor 4E (Homo sapiens (Human))	BDBM50018935 (CHEMBL3287123) Show SMILES OC(=O)C(\Cc1ccccc1[N+]([O-])=O)=N/Nc1nc-2c(CS(=O)(=O)c3c(Cl)c(Cl)ccc-23)s1 Show InChI InChI=1S/C19H12Cl2N4O6S2/c20-11-6-5-10-16-14(8-33(30,31)17(10)15(11)21)32-19(22-16)24-23-12(18(26)27)7-9-3-1-2-4-13(9)25(28)29/h1-6H,7-8H2,(H,22,24)(H,26,27)/b23-12-	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.90E+4	n/a	n/a	n/a	n/a	n/a	n/a
Harvard Medical School Curated by ChEMBL					Assay Description Displacement of N-alpha-fluorescein tagged eIF4G-derived peptide from GST-DN26-eIF4E (unknown origin) by fluorescence polarization assay				J Med Chem 57: 5094-111 (2014) Article DOI: 10.1021/jm401733v BindingDB Entry DOI: 10.7270/Q2251KR7
					More data for this Ligand-Target Pair
Eukaryotic translation initiation factor 4E (Homo sapiens (Human))	BDBM50018936 (CHEMBL3287122) Show SMILES OC(=O)C(\Cc1ccccc1[N+]([O-])=O)=N\Nc1nc-2c(CS(=O)(=O)c3c(Cl)c(Cl)ccc-23)s1 Show InChI InChI=1S/C19H12Cl2N4O6S2/c20-11-6-5-10-16-14(8-33(30,31)17(10)15(11)21)32-19(22-16)24-23-12(18(26)27)7-9-3-1-2-4-13(9)25(28)29/h1-6H,7-8H2,(H,22,24)(H,26,27)/b23-12+	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	4.05E+4	n/a	n/a	n/a	n/a	n/a	n/a
Harvard Medical School Curated by ChEMBL					Assay Description Displacement of N-alpha-fluorescein tagged eIF4G-derived peptide from GST-DN26-eIF4E (unknown origin) by fluorescence polarization assay				J Med Chem 57: 5094-111 (2014) Article DOI: 10.1021/jm401733v BindingDB Entry DOI: 10.7270/Q2251KR7
					More data for this Ligand-Target Pair
Eukaryotic translation initiation factor 4E (Homo sapiens (Human))	BDBM50018919 (CHEMBL254578) Show SMILES OC(=O)C(\Cc1ccccc1[N+]([O-])=O)=N/Nc1nc(cs1)-c1ccc(Cl)c(Cl)c1 Show InChI InChI=1S/C18H12Cl2N4O4S/c19-12-6-5-10(7-13(12)20)15-9-29-18(21-15)23-22-14(17(25)26)8-11-3-1-2-4-16(11)24(27)28/h1-7,9H,8H2,(H,21,23)(H,25,26)/b22-14-	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	4.35E+4	n/a	n/a	n/a	n/a	n/a	n/a
Harvard Medical School Curated by ChEMBL					Assay Description Displacement of N-alpha-fluorescein tagged eIF4G-derived peptide from GST-DN26-eIF4E (unknown origin) by fluorescence polarization assay				J Med Chem 57: 5094-111 (2014) Article DOI: 10.1021/jm401733v BindingDB Entry DOI: 10.7270/Q2251KR7
					More data for this Ligand-Target Pair
Eukaryotic translation initiation factor 4E (Homo sapiens (Human))	BDBM50018922 (CHEMBL3287109) Show SMILES OC(=O)C(\Cc1ccccc1[N+]([O-])=O)=N/Nc1nc-2c(CCc3c(Cl)c(Cl)ccc-23)s1 Show InChI InChI=1S/C20H14Cl2N4O4S/c21-13-7-5-12-11(17(13)22)6-8-16-18(12)23-20(31-16)25-24-14(19(27)28)9-10-3-1-2-4-15(10)26(29)30/h1-5,7H,6,8-9H2,(H,23,25)(H,27,28)/b24-14-	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	4.35E+4	n/a	n/a	n/a	n/a	n/a	n/a
Harvard Medical School Curated by ChEMBL					Assay Description Displacement of N-alpha-fluorescein tagged eIF4G-derived peptide from GST-DN26-eIF4E (unknown origin) by fluorescence polarization assay				J Med Chem 57: 5094-111 (2014) Article DOI: 10.1021/jm401733v BindingDB Entry DOI: 10.7270/Q2251KR7
					More data for this Ligand-Target Pair
Eukaryotic translation initiation factor 4E (Homo sapiens (Human))	BDBM50018923 (CHEMBL3287127) Show SMILES COc1cc2CCc3sc(N\N=C(\Cc4ccccc4[N+]([O-])=O)C(O)=O)nc3-c2cc1OC Show InChI InChI=1S/C22H20N4O6S/c1-31-17-10-12-7-8-19-20(14(12)11-18(17)32-2)23-22(33-19)25-24-15(21(27)28)9-13-5-3-4-6-16(13)26(29)30/h3-6,10-11H,7-9H2,1-2H3,(H,23,25)(H,27,28)/b24-15-	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	4.50E+4	n/a	n/a	n/a	n/a	n/a	n/a
Harvard Medical School Curated by ChEMBL					Assay Description Displacement of N-alpha-fluorescein tagged eIF4G-derived peptide from GST-DN26-eIF4E (unknown origin) by fluorescence polarization assay				J Med Chem 57: 5094-111 (2014) Article DOI: 10.1021/jm401733v BindingDB Entry DOI: 10.7270/Q2251KR7
					More data for this Ligand-Target Pair
Eukaryotic translation initiation factor 4E (Homo sapiens (Human))	BDBM50018937 (CHEMBL3287120) Show SMILES OC(=O)C(\Cc1ccccc1[N+]([O-])=O)=N\Nc1nc-2c(C[S+]([O-])c3c(Cl)c(Cl)ccc-23)s1 Show InChI InChI=1S/C19H12Cl2N4O5S2/c20-11-6-5-10-16-14(8-32(30)17(10)15(11)21)31-19(22-16)24-23-12(18(26)27)7-9-3-1-2-4-13(9)25(28)29/h1-6H,7-8H2,(H,22,24)(H,26,27)/b23-12+	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	4.85E+4	n/a	n/a	n/a	n/a	n/a	n/a
Harvard Medical School Curated by ChEMBL					Assay Description Displacement of N-alpha-fluorescein tagged eIF4G-derived peptide from GST-DN26-eIF4E (unknown origin) by fluorescence polarization assay				J Med Chem 57: 5094-111 (2014) Article DOI: 10.1021/jm401733v BindingDB Entry DOI: 10.7270/Q2251KR7
					More data for this Ligand-Target Pair
Eukaryotic translation initiation factor 4E (Homo sapiens (Human))	BDBM50018924 (CHEMBL3287124) Show SMILES OC(=O)C(\Cc1ccccc1[N+]([O-])=O)=N\Nc1nc-2c(CS(=O)(=O)c3cc(Cl)c(Cl)cc-23)s1 Show InChI InChI=1S/C19H12Cl2N4O6S2/c20-11-6-10-16(7-12(11)21)33(30,31)8-15-17(10)22-19(32-15)24-23-13(18(26)27)5-9-3-1-2-4-14(9)25(28)29/h1-4,6-7H,5,8H2,(H,22,24)(H,26,27)/b23-13+	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	4.90E+4	n/a	n/a	n/a	n/a	n/a	n/a
Harvard Medical School Curated by ChEMBL					Assay Description Displacement of N-alpha-fluorescein tagged eIF4G-derived peptide from GST-DN26-eIF4E (unknown origin) by fluorescence polarization assay				J Med Chem 57: 5094-111 (2014) Article DOI: 10.1021/jm401733v BindingDB Entry DOI: 10.7270/Q2251KR7
					More data for this Ligand-Target Pair
Eukaryotic translation initiation factor 4E (Homo sapiens (Human))	BDBM50018925 (CHEMBL3287125) Show SMILES OC(=O)C(\Cc1ccccc1[N+]([O-])=O)=N/Nc1nc-2c(CS(=O)(=O)c3cc(Cl)c(Cl)cc-23)s1 Show InChI InChI=1S/C19H12Cl2N4O6S2/c20-11-6-10-16(7-12(11)21)33(30,31)8-15-17(10)22-19(32-15)24-23-13(18(26)27)5-9-3-1-2-4-14(9)25(28)29/h1-4,6-7H,5,8H2,(H,22,24)(H,26,27)/b23-13-	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	4.90E+4	n/a	n/a	n/a	n/a	n/a	n/a
Harvard Medical School Curated by ChEMBL					Assay Description Displacement of N-alpha-fluorescein tagged eIF4G-derived peptide from GST-DN26-eIF4E (unknown origin) by fluorescence polarization assay				J Med Chem 57: 5094-111 (2014) Article DOI: 10.1021/jm401733v BindingDB Entry DOI: 10.7270/Q2251KR7
					More data for this Ligand-Target Pair
Eukaryotic translation initiation factor 4E (Homo sapiens (Human))	BDBM50018928 (CHEMBL3287131) Show SMILES COc1cc2OCc3sc(N\N=C(\Cc4ccccc4[N+]([O-])=O)C(O)=O)nc3-c2cc1OC Show InChI InChI=1S/C21H18N4O7S/c1-30-16-8-12-15(9-17(16)31-2)32-10-18-19(12)22-21(33-18)24-23-13(20(26)27)7-11-5-3-4-6-14(11)25(28)29/h3-6,8-9H,7,10H2,1-2H3,(H,22,24)(H,26,27)/b23-13-	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	5.15E+4	n/a	n/a	n/a	n/a	n/a	n/a
Harvard Medical School Curated by ChEMBL					Assay Description Displacement of N-alpha-fluorescein tagged eIF4G-derived peptide from GST-DN26-eIF4E (unknown origin) by fluorescence polarization assay				J Med Chem 57: 5094-111 (2014) Article DOI: 10.1021/jm401733v BindingDB Entry DOI: 10.7270/Q2251KR7
					More data for this Ligand-Target Pair
Eukaryotic translation initiation factor 4E (Homo sapiens (Human))	BDBM50018934 (CHEMBL3287129) Show SMILES COc1ccc2-c3nc(N\N=C(\Cc4ccccc4[N+]([O-])=O)C(O)=O)sc3COc2c1OC Show InChI InChI=1S/C21H18N4O7S/c1-30-15-8-7-12-17-16(10-32-18(12)19(15)31-2)33-21(22-17)24-23-13(20(26)27)9-11-5-3-4-6-14(11)25(28)29/h3-8H,9-10H2,1-2H3,(H,22,24)(H,26,27)/b23-13-	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	5.55E+4	n/a	n/a	n/a	n/a	n/a	n/a
Harvard Medical School Curated by ChEMBL					Assay Description Displacement of N-alpha-fluorescein tagged eIF4G-derived peptide from GST-DN26-eIF4E (unknown origin) by fluorescence polarization assay				J Med Chem 57: 5094-111 (2014) Article DOI: 10.1021/jm401733v BindingDB Entry DOI: 10.7270/Q2251KR7
					More data for this Ligand-Target Pair
Eukaryotic translation initiation factor 4E (Homo sapiens (Human))	BDBM50018919 (CHEMBL254578) Show SMILES OC(=O)C(\Cc1ccccc1[N+]([O-])=O)=N/Nc1nc(cs1)-c1ccc(Cl)c(Cl)c1 Show InChI InChI=1S/C18H12Cl2N4O4S/c19-12-6-5-10(7-13(12)20)15-9-29-18(21-15)23-22-14(17(25)26)8-11-3-1-2-4-16(11)24(27)28/h1-7,9H,8H2,(H,21,23)(H,25,26)/b22-14-	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	8.74E+6	n/a	n/a	n/a	n/a	n/a
Harvard Medical School Curated by ChEMBL					Assay Description Binding affinity to human full length recombinant GST-tagged eIF4E expressed in Escherichia coli BL21(DE3) by intrinsic tryptophan fluorescence quenc...				Eur J Med Chem 77: 361-77 (2014) Article DOI: 10.1016/j.ejmech.2014.03.034 BindingDB Entry DOI: 10.7270/Q2Z89F19
					More data for this Ligand-Target Pair
Eukaryotic translation initiation factor 4E (Homo sapiens (Human))	BDBM50044268 (CHEMBL3310215) Show SMILES Nc1ccc(C\C(=N\Nc2nc(cs2)-c2ccc(Cl)c(Cl)c2)C(O)=O)cc1[N+]([O-])=O Show InChI InChI=1S/C18H13Cl2N5O4S/c19-11-3-2-10(7-12(11)20)15-8-30-18(22-15)24-23-14(17(26)27)5-9-1-4-13(21)16(6-9)25(28)29/h1-4,6-8H,5,21H2,(H,22,24)(H,26,27)/b23-14-	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	5.01E+6	n/a	n/a	n/a	n/a	n/a
Harvard Medical School Curated by ChEMBL					Assay Description Binding affinity to human full length recombinant GST-tagged eIF4E expressed in Escherichia coli BL21(DE3) by intrinsic tryptophan fluorescence quenc...				Eur J Med Chem 77: 361-77 (2014) Article DOI: 10.1016/j.ejmech.2014.03.034 BindingDB Entry DOI: 10.7270/Q2Z89F19
					More data for this Ligand-Target Pair
Eukaryotic translation initiation factor 4E (Homo sapiens (Human))	BDBM50044269 (CHEMBL3310347) Show SMILES OC(=O)C(\Cc1ccccc1[N+]([O-])=O)=N/Nc1nc(cs1)-c1ccc(O)cc1 Show InChI InChI=1S/C18H14N4O5S/c23-13-7-5-11(6-8-13)15-10-28-18(19-15)21-20-14(17(24)25)9-12-3-1-2-4-16(12)22(26)27/h1-8,10,23H,9H2,(H,19,21)(H,24,25)/b20-14-	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	3.66E+7	n/a	n/a	n/a	n/a	n/a
Harvard Medical School Curated by ChEMBL					Assay Description Binding affinity to human full length recombinant GST-tagged eIF4E expressed in Escherichia coli BL21(DE3) by intrinsic tryptophan fluorescence quenc...				Eur J Med Chem 77: 361-77 (2014) Article DOI: 10.1016/j.ejmech.2014.03.034 BindingDB Entry DOI: 10.7270/Q2Z89F19
					More data for this Ligand-Target Pair