Compile Data Set for Download or QSAR

Found 84 hits with Last Name = 'al-abed' and Initial = 'y'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Macrophage migration inhibitory factor (Homo sapiens (Human))	BDBM50209085 (3-fluoro-4-hydroxybenzaldehyde (4-methoxyphenyl)hy...) Show SMILES COc1ccc(cc1)N=NCc1ccc(O)c(F)c1 |w:9.10| Show InChI InChI=1S/C14H13FN2O2/c1-19-12-5-3-11(4-6-12)17-16-9-10-2-7-14(18)13(15)8-10/h2-8,18H,9H2,1H3	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	130	n/a	n/a	n/a	n/a	n/a	n/a
and The New York School of Medicine Curated by ChEMBL					Assay Description Inhibition of MIF tautomerase activity by spectrophotometric assay				J Med Chem 50: 1993-7 (2007) Article DOI: 10.1021/jm061477+ BindingDB Entry DOI: 10.7270/Q23X869D
					More data for this Ligand-Target Pair
Macrophage migration inhibitory factor (Homo sapiens (Human))	BDBM50209081 (3-chloro-4-hydroxybenzaldehyde (4-methoxyphenyl)hy...) Show SMILES COc1ccc(cc1)N=NCc1ccc(O)c(Cl)c1 |w:9.10| Show InChI InChI=1S/C14H13ClN2O2/c1-19-12-5-3-11(4-6-12)17-16-9-10-2-7-14(18)13(15)8-10/h2-8,18H,9H2,1H3	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	220	n/a	n/a	n/a	n/a	n/a	n/a
and The New York School of Medicine Curated by ChEMBL					Assay Description Inhibition of MIF tautomerase activity by spectrophotometric assay				J Med Chem 50: 1993-7 (2007) Article DOI: 10.1021/jm061477+ BindingDB Entry DOI: 10.7270/Q23X869D
					More data for this Ligand-Target Pair
Macrophage migration inhibitory factor (Homo sapiens (Human))	BDBM50209089 (3-bromo-4-hydroxybenzaldehyde (4-methoxyphenyl)hyd...) Show SMILES COc1ccc(cc1)N=NCc1ccc(O)c(Br)c1 |w:9.10| Show InChI InChI=1S/C14H13BrN2O2/c1-19-12-5-3-11(4-6-12)17-16-9-10-2-7-14(18)13(15)8-10/h2-8,18H,9H2,1H3	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	330	n/a	n/a	n/a	n/a	n/a	n/a
and The New York School of Medicine Curated by ChEMBL					Assay Description Inhibition of MIF tautomerase activity by spectrophotometric assay				J Med Chem 50: 1993-7 (2007) Article DOI: 10.1021/jm061477+ BindingDB Entry DOI: 10.7270/Q23X869D
					More data for this Ligand-Target Pair
Macrophage migration inhibitory factor (Homo sapiens (Human))	BDBM50209090 (4-hydroxybenzaldehyde (4-methoxyphenyl)hydrazone |...) Show SMILES COc1ccc(cc1)N=NCc1ccc(O)cc1 |w:9.10| Show InChI InChI=1S/C14H14N2O2/c1-18-14-8-4-12(5-9-14)16-15-10-11-2-6-13(17)7-3-11/h2-9,17H,10H2,1H3	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	480	n/a	n/a	n/a	n/a	n/a	n/a
and The New York School of Medicine Curated by ChEMBL					Assay Description Inhibition of MIF tautomerase activity by spectrophotometric assay				J Med Chem 50: 1993-7 (2007) Article DOI: 10.1021/jm061477+ BindingDB Entry DOI: 10.7270/Q23X869D
					More data for this Ligand-Target Pair
Macrophage migration inhibitory factor (Homo sapiens (Human))	BDBM50186440 ((R)-1-(3-(3-fluoro-4-hydroxyphenyl)-4,5-dihydroiso...) Show SMILES CC(C)(C)CC(=O)C[C@H]1CC(=NO1)c1ccc(O)c(F)c1 |c:10| Show InChI InChI=1S/C16H20FNO3/c1-16(2,3)9-11(19)7-12-8-14(18-21-12)10-4-5-15(20)13(17)6-10/h4-6,12,20H,7-9H2,1-3H3/t12-/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	550	n/a	n/a	n/a	n/a	n/a	n/a
Institute for Medical Research Curated by ChEMBL					Assay Description Inhibition of MIF tautomerase activity				Bioorg Med Chem Lett 16: 3376-9 (2006) Article DOI: 10.1016/j.bmcl.2006.04.038 BindingDB Entry DOI: 10.7270/Q27W6BSG
					More data for this Ligand-Target Pair
Macrophage migration inhibitory factor (Homo sapiens (Human))	BDBM50186444 (CHEMBL211882 | neopentyl 2-(3-(3-fluoro-4-hydroxyp...) Show SMILES CC(C)(C)COC(=O)CC1CC(=NO1)c1ccc(O)c(F)c1 |c:11| Show InChI InChI=1S/C16H20FNO4/c1-16(2,3)9-21-15(20)8-11-7-13(18-22-11)10-4-5-14(19)12(17)6-10/h4-6,11,19H,7-9H2,1-3H3	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	750	n/a	n/a	n/a	n/a	n/a	n/a
Institute for Medical Research Curated by ChEMBL					Assay Description Inhibition of MIF tautomerase activity				Bioorg Med Chem Lett 16: 3376-9 (2006) Article DOI: 10.1016/j.bmcl.2006.04.038 BindingDB Entry DOI: 10.7270/Q27W6BSG
					More data for this Ligand-Target Pair
Macrophage migration inhibitory factor (Homo sapiens (Human))	BDBM50186438 ((S)-1-(3-(3-fluoro-4-hydroxyphenyl)-4,5-dihydroiso...) Show SMILES CC(C)(C)CC(=O)C[C@@H]1CC(=NO1)c1ccc(O)c(F)c1 |c:10| Show InChI InChI=1S/C16H20FNO3/c1-16(2,3)9-11(19)7-12-8-14(18-21-12)10-4-5-15(20)13(17)6-10/h4-6,12,20H,7-9H2,1-3H3/t12-/m1/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.10E+3	n/a	n/a	n/a	n/a	n/a	n/a
Institute for Medical Research Curated by ChEMBL					Assay Description Inhibition of MIF tautomerase activity				Bioorg Med Chem Lett 16: 3376-9 (2006) Article DOI: 10.1016/j.bmcl.2006.04.038 BindingDB Entry DOI: 10.7270/Q27W6BSG
					More data for this Ligand-Target Pair
Macrophage migration inhibitory factor (Homo sapiens (Human))	BDBM50373155 (CHEMBL253951) Show SMILES Oc1ccc(C=NOC(=O)C2CCCCC2)cc1 |w:5.4| Show InChI InChI=1S/C14H17NO3/c16-13-8-6-11(7-9-13)10-15-18-14(17)12-4-2-1-3-5-12/h6-10,12,16H,1-5H2	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL MMDB PC cid PC sid PDB UniChem Similars	MMDB PDB Article PubMed	n/a	n/a	1.30E+3	n/a	n/a	n/a	n/a	n/a	n/a
Yale University Curated by ChEMBL					Assay Description Inhibition of MIF-mediated dopachrome tautomerase activity				J Biol Chem 282: 23089-95 (2007) Article DOI: 10.1074/jbc.M701825200 BindingDB Entry DOI: 10.7270/Q2KS6SD0
					More data for this Ligand-Target Pair				3D Structure (crystal)
Macrophage migration inhibitory factor (Mus musculus (Mouse))	BDBM50186443 (CHEMBL210592 | US8618147, 16 | neopentyl 2-(3-(4-h...) Show SMILES CC(C)(C)COC(=O)CC1CC(=NO1)c1ccc(O)cc1 |c:11| Show InChI InChI=1S/C16H21NO4/c1-16(2,3)10-20-15(19)9-13-8-14(17-21-13)11-4-6-12(18)7-5-11/h4-7,13,18H,8-10H2,1-3H3	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	US Patent	n/a	n/a	1.50E+3	n/a	n/a	n/a	n/a	7.2	25
The Feinstein Institute for Medical Research US Patent					Assay Description MIF tautomerase activity was measured by UV-Visible recording spectrophotometry (SHIMADZU, UV1600U). A fresh stock solution of L-dopachrome methyl es...				US Patent US8618147 (2013) BindingDB Entry DOI: 10.7270/Q23R0RHZ
					More data for this Ligand-Target Pair
Macrophage migration inhibitory factor (Homo sapiens (Human))	BDBM50186443 (CHEMBL210592 | US8618147, 16 | neopentyl 2-(3-(4-h...) Show SMILES CC(C)(C)COC(=O)CC1CC(=NO1)c1ccc(O)cc1 |c:11| Show InChI InChI=1S/C16H21NO4/c1-16(2,3)10-20-15(19)9-13-8-14(17-21-13)11-4-6-12(18)7-5-11/h4-7,13,18H,8-10H2,1-3H3	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.50E+3	n/a	n/a	n/a	n/a	n/a	n/a
Institute for Medical Research Curated by ChEMBL					Assay Description Inhibition of MIF tautomerase activity				Bioorg Med Chem Lett 16: 3376-9 (2006) Article DOI: 10.1016/j.bmcl.2006.04.038 BindingDB Entry DOI: 10.7270/Q27W6BSG
					More data for this Ligand-Target Pair
Macrophage migration inhibitory factor (Homo sapiens (Human))	BDBM50113768 ((S)-methyl 2-(4-hydroxybenzylideneamino)-3-(1H-ind...) Show SMILES COC(=O)[C@H](Cc1c[nH]c2ccccc12)\N=C\c1ccc(O)cc1 |r| Show InChI InChI=1S/C19H18N2O3/c1-24-19(23)18(20-11-13-6-8-15(22)9-7-13)10-14-12-21-17-5-3-2-4-16(14)17/h2-9,11-12,18,21-22H,10H2,1H3/b20-11+/t18-/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.60E+3	n/a	n/a	n/a	n/a	n/a	n/a
and The New York School of Medicine Curated by ChEMBL					Assay Description Inhibition of MIF tautomerase activity by spectrophotometric assay				J Med Chem 50: 1993-7 (2007) Article DOI: 10.1021/jm061477+ BindingDB Entry DOI: 10.7270/Q23X869D
					More data for this Ligand-Target Pair
Macrophage migration inhibitory factor (Homo sapiens (Human))	BDBM50113768 ((S)-methyl 2-(4-hydroxybenzylideneamino)-3-(1H-ind...) Show SMILES COC(=O)[C@H](Cc1c[nH]c2ccccc12)\N=C\c1ccc(O)cc1 |r| Show InChI InChI=1S/C19H18N2O3/c1-24-19(23)18(20-11-13-6-8-15(22)9-7-13)10-14-12-21-17-5-3-2-4-16(14)17/h2-9,11-12,18,21-22H,10H2,1H3/b20-11+/t18-/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	1.65E+3	n/a	n/a	n/a	n/a	n/a	n/a
Institute for Medical Research Curated by ChEMBL					Assay Description Inhibition of human macrophage migration inhibitory factor tautomerase (MIF) activity				J Med Chem 45: 2410-6 (2002) BindingDB Entry DOI: 10.7270/Q2WS8SKS
					More data for this Ligand-Target Pair
Macrophage migration inhibitory factor (Mus musculus (Mouse))	BDBM50186445 (CHEMBL209401 | US8618147, 14 | cyclohexyl 2-(3-(4-...) Show SMILES Oc1ccc(cc1)C1=NOC(CC(=O)OC2CCCCC2)C1 |t:8| Show InChI InChI=1S/C17H21NO4/c19-13-8-6-12(7-9-13)16-10-15(22-18-16)11-17(20)21-14-4-2-1-3-5-14/h6-9,14-15,19H,1-5,10-11H2	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	US Patent	n/a	n/a	2.50E+3	n/a	n/a	n/a	n/a	7.2	25
The Feinstein Institute for Medical Research US Patent					Assay Description MIF tautomerase activity was measured by UV-Visible recording spectrophotometry (SHIMADZU, UV1600U). A fresh stock solution of L-dopachrome methyl es...				US Patent US8618147 (2013) BindingDB Entry DOI: 10.7270/Q23R0RHZ
					More data for this Ligand-Target Pair
Macrophage migration inhibitory factor (Homo sapiens (Human))	BDBM50186445 (CHEMBL209401 | US8618147, 14 | cyclohexyl 2-(3-(4-...) Show SMILES Oc1ccc(cc1)C1=NOC(CC(=O)OC2CCCCC2)C1 |t:8| Show InChI InChI=1S/C17H21NO4/c19-13-8-6-12(7-9-13)16-10-15(22-18-16)11-17(20)21-14-4-2-1-3-5-14/h6-9,14-15,19H,1-5,10-11H2	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	2.50E+3	n/a	n/a	n/a	n/a	n/a	n/a
Institute for Medical Research Curated by ChEMBL					Assay Description Inhibition of MIF tautomerase activity				Bioorg Med Chem Lett 16: 3376-9 (2006) Article DOI: 10.1016/j.bmcl.2006.04.038 BindingDB Entry DOI: 10.7270/Q27W6BSG
					More data for this Ligand-Target Pair
Macrophage migration inhibitory factor (Homo sapiens (Human))	BDBM50209091 (4-hydroxybenzaldehyde phenylhydrazone | CHEMBL2240...) Show SMILES Oc1ccc(CN=Nc2ccccc2)cc1 |w:6.5| Show InChI InChI=1S/C13H12N2O/c16-13-8-6-11(7-9-13)10-14-15-12-4-2-1-3-5-12/h1-9,16H,10H2	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.60E+3	n/a	n/a	n/a	n/a	n/a	n/a
and The New York School of Medicine Curated by ChEMBL					Assay Description Inhibition of MIF tautomerase activity by spectrophotometric assay				J Med Chem 50: 1993-7 (2007) Article DOI: 10.1021/jm061477+ BindingDB Entry DOI: 10.7270/Q23X869D
					More data for this Ligand-Target Pair
Macrophage migration inhibitory factor (Homo sapiens (Human))	BDBM50373156 (CHEMBL253950) Show SMILES Oc1ccc(C=NOC(=O)CCC2CCCCC2)cc1 |w:5.4| Show InChI InChI=1S/C16H21NO3/c18-15-9-6-14(7-10-15)12-17-20-16(19)11-8-13-4-2-1-3-5-13/h6-7,9-10,12-13,18H,1-5,8,11H2	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Yale University Curated by ChEMBL					Assay Description Inhibition of MIF-mediated dopachrome tautomerase activity				J Biol Chem 282: 23089-95 (2007) Article DOI: 10.1074/jbc.M701825200 BindingDB Entry DOI: 10.7270/Q2KS6SD0
					More data for this Ligand-Target Pair
Macrophage migration inhibitory factor (Homo sapiens (Human))	BDBM50186429 (CHEMBL210755 | US8618147, 13 | butyl 2-(3-(4-hydro...) Show SMILES CCCCOC(=O)CC1CC(=NO1)c1ccc(O)cc1 |c:10| Show InChI InChI=1S/C15H19NO4/c1-2-3-8-19-15(18)10-13-9-14(16-20-13)11-4-6-12(17)7-5-11/h4-7,13,17H,2-3,8-10H2,1H3	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Institute for Medical Research Curated by ChEMBL					Assay Description Inhibition of MIF tautomerase activity				Bioorg Med Chem Lett 16: 3376-9 (2006) Article DOI: 10.1016/j.bmcl.2006.04.038 BindingDB Entry DOI: 10.7270/Q27W6BSG
					More data for this Ligand-Target Pair
Macrophage migration inhibitory factor (Mus musculus (Mouse))	BDBM50186429 (CHEMBL210755 | US8618147, 13 | butyl 2-(3-(4-hydro...) Show SMILES CCCCOC(=O)CC1CC(=NO1)c1ccc(O)cc1 |c:10| Show InChI InChI=1S/C15H19NO4/c1-2-3-8-19-15(18)10-13-9-14(16-20-13)11-4-6-12(17)7-5-11/h4-7,13,17H,2-3,8-10H2,1H3	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	US Patent	n/a	n/a	3.00E+3	n/a	n/a	n/a	n/a	7.2	25
The Feinstein Institute for Medical Research US Patent					Assay Description MIF tautomerase activity was measured by UV-Visible recording spectrophotometry (SHIMADZU, UV1600U). A fresh stock solution of L-dopachrome methyl es...				US Patent US8618147 (2013) BindingDB Entry DOI: 10.7270/Q23R0RHZ
					More data for this Ligand-Target Pair
Macrophage migration inhibitory factor (Homo sapiens (Human))	BDBM50373163 (CHEMBL256939) Show SMILES Oc1ccc(C=NOC(=O)C2CCC=CC2)cc1 |w:5.4,c:13| Show InChI InChI=1S/C14H15NO3/c16-13-8-6-11(7-9-13)10-15-18-14(17)12-4-2-1-3-5-12/h1-2,6-10,12,16H,3-5H2	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	3.40E+3	n/a	n/a	n/a	n/a	n/a	n/a
Yale University Curated by ChEMBL					Assay Description Inhibition of MIF-mediated dopachrome tautomerase activity				J Biol Chem 282: 23089-95 (2007) Article DOI: 10.1074/jbc.M701825200 BindingDB Entry DOI: 10.7270/Q2KS6SD0
					More data for this Ligand-Target Pair
Macrophage migration inhibitory factor (Mus musculus (Mouse))	BDBM50186439 (CHEMBL208659 | US8618147, 11 | propyl 2-(3-(4-hydr...) Show SMILES CCCOC(=O)CC1CC(=NO1)c1ccc(O)cc1 |c:9| Show InChI InChI=1S/C14H17NO4/c1-2-7-18-14(17)9-12-8-13(15-19-12)10-3-5-11(16)6-4-10/h3-6,12,16H,2,7-9H2,1H3	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	US Patent	n/a	n/a	4.00E+3	n/a	n/a	n/a	n/a	7.2	25
The Feinstein Institute for Medical Research US Patent					Assay Description MIF tautomerase activity was measured by UV-Visible recording spectrophotometry (SHIMADZU, UV1600U). A fresh stock solution of L-dopachrome methyl es...				US Patent US8618147 (2013) BindingDB Entry DOI: 10.7270/Q23R0RHZ
					More data for this Ligand-Target Pair
Macrophage migration inhibitory factor (Homo sapiens (Human))	BDBM50186439 (CHEMBL208659 | US8618147, 11 | propyl 2-(3-(4-hydr...) Show SMILES CCCOC(=O)CC1CC(=NO1)c1ccc(O)cc1 |c:9| Show InChI InChI=1S/C14H17NO4/c1-2-7-18-14(17)9-12-8-13(15-19-12)10-3-5-11(16)6-4-10/h3-6,12,16H,2,7-9H2,1H3	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	4.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Institute for Medical Research Curated by ChEMBL					Assay Description Inhibition of MIF tautomerase activity				Bioorg Med Chem Lett 16: 3376-9 (2006) Article DOI: 10.1016/j.bmcl.2006.04.038 BindingDB Entry DOI: 10.7270/Q27W6BSG
					More data for this Ligand-Target Pair
Macrophage migration inhibitory factor (Homo sapiens (Human))	BDBM50373157 (CHEMBL257350) Show SMILES Oc1ccc(C=NOC(=O)C2CCCC2)cc1 |w:5.4| Show InChI InChI=1S/C13H15NO3/c15-12-7-5-10(6-8-12)9-14-17-13(16)11-3-1-2-4-11/h5-9,11,15H,1-4H2	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	4.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Yale University Curated by ChEMBL					Assay Description Inhibition of MIF-mediated dopachrome tautomerase activity				J Biol Chem 282: 23089-95 (2007) Article DOI: 10.1074/jbc.M701825200 BindingDB Entry DOI: 10.7270/Q2KS6SD0
					More data for this Ligand-Target Pair
Macrophage migration inhibitory factor (Homo sapiens (Human))	BDBM50186430 (CHEMBL377184 | US8618147, 15 | cyclohexylmethyl 2-...) Show SMILES Oc1ccc(cc1)C1=NOC(CC(=O)OCC2CCCCC2)C1 |t:8| Show InChI InChI=1S/C18H23NO4/c20-15-8-6-14(7-9-15)17-10-16(23-19-17)11-18(21)22-12-13-4-2-1-3-5-13/h6-9,13,16,20H,1-5,10-12H2	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	5.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Institute for Medical Research Curated by ChEMBL					Assay Description Inhibition of MIF tautomerase activity				Bioorg Med Chem Lett 16: 3376-9 (2006) Article DOI: 10.1016/j.bmcl.2006.04.038 BindingDB Entry DOI: 10.7270/Q27W6BSG
					More data for this Ligand-Target Pair
Macrophage migration inhibitory factor (Mus musculus (Mouse))	BDBM50186430 (CHEMBL377184 | US8618147, 15 | cyclohexylmethyl 2-...) Show SMILES Oc1ccc(cc1)C1=NOC(CC(=O)OCC2CCCCC2)C1 |t:8| Show InChI InChI=1S/C18H23NO4/c20-15-8-6-14(7-9-15)17-10-16(23-19-17)11-18(21)22-12-13-4-2-1-3-5-13/h6-9,13,16,20H,1-5,10-12H2	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	US Patent	n/a	n/a	5.00E+3	n/a	n/a	n/a	n/a	7.2	25
The Feinstein Institute for Medical Research US Patent					Assay Description MIF tautomerase activity was measured by UV-Visible recording spectrophotometry (SHIMADZU, UV1600U). A fresh stock solution of L-dopachrome methyl es...				US Patent US8618147 (2013) BindingDB Entry DOI: 10.7270/Q23R0RHZ
					More data for this Ligand-Target Pair
Macrophage migration inhibitory factor (Homo sapiens (Human))	BDBM50209092 (CHEMBL221727 | tert-butyl-2-(4-hydroxybenzylidene)...) Show SMILES CC(C)(C)OC(=O)NN=Cc1ccc(O)cc1 |w:9.9| Show InChI InChI=1S/C12H16N2O3/c1-12(2,3)17-11(16)14-13-8-9-4-6-10(15)7-5-9/h4-8,15H,1-3H3,(H,14,16)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	5.50E+3	n/a	n/a	n/a	n/a	n/a	n/a
and The New York School of Medicine Curated by ChEMBL					Assay Description Inhibition of MIF tautomerase activity by spectrophotometric assay				J Med Chem 50: 1993-7 (2007) Article DOI: 10.1021/jm061477+ BindingDB Entry DOI: 10.7270/Q23X869D
					More data for this Ligand-Target Pair
Macrophage migration inhibitory factor (Homo sapiens (Human))	BDBM50186425 (CHEMBL208716 | US8618147, 12 | isopropyl 2-(3-(4-h...) Show SMILES CC(C)OC(=O)CC1CC(=NO1)c1ccc(O)cc1 |c:9| Show InChI InChI=1S/C14H17NO4/c1-9(2)18-14(17)8-12-7-13(15-19-12)10-3-5-11(16)6-4-10/h3-6,9,12,16H,7-8H2,1-2H3	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	6.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Institute for Medical Research Curated by ChEMBL					Assay Description Inhibition of MIF tautomerase activity				Bioorg Med Chem Lett 16: 3376-9 (2006) Article DOI: 10.1016/j.bmcl.2006.04.038 BindingDB Entry DOI: 10.7270/Q27W6BSG
					More data for this Ligand-Target Pair
Macrophage migration inhibitory factor (Mus musculus (Mouse))	BDBM50186425 (CHEMBL208716 | US8618147, 12 | isopropyl 2-(3-(4-h...) Show SMILES CC(C)OC(=O)CC1CC(=NO1)c1ccc(O)cc1 |c:9| Show InChI InChI=1S/C14H17NO4/c1-9(2)18-14(17)8-12-7-13(15-19-12)10-3-5-11(16)6-4-10/h3-6,9,12,16H,7-8H2,1-2H3	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	US Patent	n/a	n/a	6.00E+3	n/a	n/a	n/a	n/a	7.2	25
The Feinstein Institute for Medical Research US Patent					Assay Description MIF tautomerase activity was measured by UV-Visible recording spectrophotometry (SHIMADZU, UV1600U). A fresh stock solution of L-dopachrome methyl es...				US Patent US8618147 (2013) BindingDB Entry DOI: 10.7270/Q23R0RHZ
					More data for this Ligand-Target Pair
Macrophage migration inhibitory factor (Homo sapiens (Human))	BDBM50186427 (CHEMBL212313 | methyl 2-(3-(3-fluoro-4-hydroxyphen...) Show SMILES COC(=O)CC1CC(=NO1)c1ccc(O)c(F)c1 |c:7| Show InChI InChI=1S/C12H12FNO4/c1-17-12(16)6-8-5-10(14-18-8)7-2-3-11(15)9(13)4-7/h2-4,8,15H,5-6H2,1H3	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	6.50E+3	n/a	n/a	n/a	n/a	n/a	n/a
Institute for Medical Research Curated by ChEMBL					Assay Description Inhibition of MIF tautomerase activity				Bioorg Med Chem Lett 16: 3376-9 (2006) Article DOI: 10.1016/j.bmcl.2006.04.038 BindingDB Entry DOI: 10.7270/Q27W6BSG
					More data for this Ligand-Target Pair
Macrophage migration inhibitory factor (Homo sapiens (Human))	BDBM50209080 (CHEMBL384671 | methyl 2-(3-(4-hydroxyphenyl)-4,5-d...) Show SMILES COC(=O)CC1CON=C1c1ccc(O)cc1 |c:8| Show InChI InChI=1S/C12H13NO4/c1-16-11(15)6-9-7-17-13-12(9)8-2-4-10(14)5-3-8/h2-5,9,14H,6-7H2,1H3	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	7.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
and The New York School of Medicine Curated by ChEMBL					Assay Description Inhibition of MIF tautomerase activity by spectrophotometric assay				J Med Chem 50: 1993-7 (2007) Article DOI: 10.1021/jm061477+ BindingDB Entry DOI: 10.7270/Q23X869D
					More data for this Ligand-Target Pair
Macrophage migration inhibitory factor (Homo sapiens (Human))	BDBM50186434 ((R)-methyl 2-(3-(4-hydroxyphenyl)-4,5-dihydroisoxa...) Show SMILES COC(=O)C[C@H]1CC(=NO1)c1ccc(O)cc1 |r,c:7| Show InChI InChI=1S/C12H13NO4/c1-16-12(15)7-10-6-11(13-17-10)8-2-4-9(14)5-3-8/h2-5,10,14H,6-7H2,1H3/t10-/m1/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE PC cid PC sid PDB UniChem Patents Similars	DrugBank PDB Article PubMed	n/a	n/a	7.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Institute for Medical Research Curated by ChEMBL					Assay Description Inhibition of MIF tautomerase activity				Bioorg Med Chem Lett 16: 3376-9 (2006) Article DOI: 10.1016/j.bmcl.2006.04.038 BindingDB Entry DOI: 10.7270/Q27W6BSG
					More data for this Ligand-Target Pair				3D Structure (crystal)
Macrophage migration inhibitory factor (Homo sapiens (Human))	BDBM50373164 (CHEMBL256314) Show SMILES CC(C)CC(=O)ON=Cc1ccc(O)cc1 |w:8.8| Show InChI InChI=1S/C12H15NO3/c1-9(2)7-12(15)16-13-8-10-3-5-11(14)6-4-10/h3-6,8-9,14H,7H2,1-2H3	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	7.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Yale University Curated by ChEMBL					Assay Description Inhibition of MIF-mediated dopachrome tautomerase activity				J Biol Chem 282: 23089-95 (2007) Article DOI: 10.1074/jbc.M701825200 BindingDB Entry DOI: 10.7270/Q2KS6SD0
					More data for this Ligand-Target Pair
Macrophage migration inhibitory factor (Homo sapiens (Human))	BDBM50373159 (CHEMBL256315) Show SMILES CC(C)(C)CC(=O)ON=Cc1ccc(O)cc1 |w:9.9| Show InChI InChI=1S/C13H17NO3/c1-13(2,3)8-12(16)17-14-9-10-4-6-11(15)7-5-10/h4-7,9,15H,8H2,1-3H3	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid PDB UniChem Similars	PDB Article PubMed	n/a	n/a	7.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Yale University Curated by ChEMBL					Assay Description Inhibition of MIF-mediated dopachrome tautomerase activity				J Biol Chem 282: 23089-95 (2007) Article DOI: 10.1074/jbc.M701825200 BindingDB Entry DOI: 10.7270/Q2KS6SD0
					More data for this Ligand-Target Pair				3D Structure (crystal)
Macrophage migration inhibitory factor (Homo sapiens (Human))	BDBM50373154 (CHEMBL257614) Show SMILES Oc1ccc(\C=N\OC(=O)c2ccccc2)cc1 Show InChI InChI=1S/C14H11NO3/c16-13-8-6-11(7-9-13)10-15-18-14(17)12-4-2-1-3-5-12/h1-10,16H/b15-10+	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	7.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Yale University Curated by ChEMBL					Assay Description Inhibition of MIF-mediated dopachrome tautomerase activity				J Biol Chem 282: 23089-95 (2007) Article DOI: 10.1074/jbc.M701825200 BindingDB Entry DOI: 10.7270/Q2KS6SD0
					More data for this Ligand-Target Pair
Macrophage migration inhibitory factor (Homo sapiens (Human))	BDBM50209083 (4-methoxybenzyl-2-(4-hydroxybenzylidene)hydrazinec...) Show SMILES COc1ccc(COC(=O)NN=Cc2ccc(O)cc2)cc1 |w:12.12| Show InChI InChI=1S/C16H16N2O4/c1-21-15-8-4-13(5-9-15)11-22-16(20)18-17-10-12-2-6-14(19)7-3-12/h2-10,19H,11H2,1H3,(H,18,20)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	8.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
and The New York School of Medicine Curated by ChEMBL					Assay Description Inhibition of MIF tautomerase activity by spectrophotometric assay				J Med Chem 50: 1993-7 (2007) Article DOI: 10.1021/jm061477+ BindingDB Entry DOI: 10.7270/Q23X869D
					More data for this Ligand-Target Pair
Macrophage migration inhibitory factor (Mus musculus (Mouse))	BDBM111576 (US8618147, 3) Show SMILES OOc1ccc(OC(=O)CC2CC(=NO2)c2ccc(O)cc2)cc1 |c:12| Show InChI InChI=1S/C17H15NO6/c19-12-3-1-11(2-4-12)16-9-15(23-18-16)10-17(20)22-13-5-7-14(24-21)8-6-13/h1-8,15,19,21H,9-10H2	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	KEGG PC cid PC sid UniChem Similars	US Patent	n/a	n/a	8.50E+3	n/a	n/a	n/a	n/a	7.2	25
The Feinstein Institute for Medical Research US Patent					Assay Description MIF tautomerase activity was measured by UV-Visible recording spectrophotometry (SHIMADZU, UV1600U). A fresh stock solution of L-dopachrome methyl es...				US Patent US8618147 (2013) BindingDB Entry DOI: 10.7270/Q23R0RHZ
					More data for this Ligand-Target Pair
Macrophage migration inhibitory factor (Homo sapiens (Human))	BDBM50186431 (CHEMBL210529 | US8618147, 8 | tert-butyl 4-(2-(3-(...) Show SMILES CC(C)(C)OC(=O)NCCCCNC(=O)CC1CC(=NO1)c1ccc(O)cc1 |c:18| Show InChI InChI=1S/C20H29N3O5/c1-20(2,3)27-19(26)22-11-5-4-10-21-18(25)13-16-12-17(23-28-16)14-6-8-15(24)9-7-14/h6-9,16,24H,4-5,10-13H2,1-3H3,(H,21,25)(H,22,26)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	8.50E+3	n/a	n/a	n/a	n/a	n/a	n/a
Institute for Medical Research Curated by ChEMBL					Assay Description Inhibition of MIF tautomerase activity				Bioorg Med Chem Lett 16: 3376-9 (2006) Article DOI: 10.1016/j.bmcl.2006.04.038 BindingDB Entry DOI: 10.7270/Q27W6BSG
					More data for this Ligand-Target Pair
Macrophage migration inhibitory factor (Mus musculus (Mouse))	BDBM50186431 (CHEMBL210529 | US8618147, 8 | tert-butyl 4-(2-(3-(...) Show SMILES CC(C)(C)OC(=O)NCCCCNC(=O)CC1CC(=NO1)c1ccc(O)cc1 |c:18| Show InChI InChI=1S/C20H29N3O5/c1-20(2,3)27-19(26)22-11-5-4-10-21-18(25)13-16-12-17(23-28-16)14-6-8-15(24)9-7-14/h6-9,16,24H,4-5,10-13H2,1-3H3,(H,21,25)(H,22,26)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	US Patent	n/a	n/a	8.50E+3	n/a	n/a	n/a	n/a	7.2	25
The Feinstein Institute for Medical Research US Patent					Assay Description MIF tautomerase activity was measured by UV-Visible recording spectrophotometry (SHIMADZU, UV1600U). A fresh stock solution of L-dopachrome methyl es...				US Patent US8618147 (2013) BindingDB Entry DOI: 10.7270/Q23R0RHZ
					More data for this Ligand-Target Pair
Macrophage migration inhibitory factor (Homo sapiens (Human))	BDBM50186433 (4-methoxyphenyl 2-(3-(4-hydroxyphenyl)-4,5-dihydro...) Show SMILES COc1ccc(OC(=O)CC2CC(=NO2)c2ccc(O)cc2)cc1 |c:12| Show InChI InChI=1S/C18H17NO5/c1-22-14-6-8-15(9-7-14)23-18(21)11-16-10-17(19-24-16)12-2-4-13(20)5-3-12/h2-9,16,20H,10-11H2,1H3	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	8.50E+3	n/a	n/a	n/a	n/a	n/a	n/a
Institute for Medical Research Curated by ChEMBL					Assay Description Inhibition of MIF tautomerase activity				Bioorg Med Chem Lett 16: 3376-9 (2006) Article DOI: 10.1016/j.bmcl.2006.04.038 BindingDB Entry DOI: 10.7270/Q27W6BSG
					More data for this Ligand-Target Pair
Macrophage migration inhibitory factor (Mus musculus (Mouse))	BDBM50186424 (CHEMBL377038 | US8618147, 2 | phenyl 2-(3-(4-hydro...) Show SMILES Oc1ccc(cc1)C1=NOC(CC(=O)Oc2ccccc2)C1 |t:8| Show InChI InChI=1S/C17H15NO4/c19-13-8-6-12(7-9-13)16-10-15(22-18-16)11-17(20)21-14-4-2-1-3-5-14/h1-9,15,19H,10-11H2	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	US Patent	n/a	n/a	1.00E+4	n/a	n/a	n/a	n/a	7.2	25
The Feinstein Institute for Medical Research US Patent					Assay Description MIF tautomerase activity was measured by UV-Visible recording spectrophotometry (SHIMADZU, UV1600U). A fresh stock solution of L-dopachrome methyl es...				US Patent US8618147 (2013) BindingDB Entry DOI: 10.7270/Q23R0RHZ
					More data for this Ligand-Target Pair
Macrophage migration inhibitory factor (Mus musculus (Mouse))	BDBM50186432 (4-tert-butylphenyl 2-(3-(4-hydroxyphenyl)-4,5-dihy...) Show SMILES CC(C)(C)c1ccc(OC(=O)CC2CC(=NO2)c2ccc(O)cc2)cc1 |c:14| Show InChI InChI=1S/C21H23NO4/c1-21(2,3)15-6-10-17(11-7-15)25-20(24)13-18-12-19(22-26-18)14-4-8-16(23)9-5-14/h4-11,18,23H,12-13H2,1-3H3	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	US Patent	n/a	n/a	1.00E+4	n/a	n/a	n/a	n/a	7.2	25
The Feinstein Institute for Medical Research US Patent					Assay Description MIF tautomerase activity was measured by UV-Visible recording spectrophotometry (SHIMADZU, UV1600U). A fresh stock solution of L-dopachrome methyl es...				US Patent US8618147 (2013) BindingDB Entry DOI: 10.7270/Q23R0RHZ
					More data for this Ligand-Target Pair
Macrophage migration inhibitory factor (Homo sapiens (Human))	BDBM50113775 (2-[(4-Hydroxy-benzylidene)-amino]-3-(4-hydroxy-phe...) Show SMILES COC(=O)[C@@H](Cc1ccc(O)cc1)\N=C\c1ccc(O)cc1 Show InChI InChI=1S/C17H17NO4/c1-22-17(21)16(10-12-2-6-14(19)7-3-12)18-11-13-4-8-15(20)9-5-13/h2-9,11,16,19-20H,10H2,1H3/b18-11+/t16-/m1/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Institute for Medical Research Curated by ChEMBL					Assay Description Inhibition of human macrophage migration inhibitory factor tautomerase (MIF) activity				J Med Chem 45: 2410-6 (2002) BindingDB Entry DOI: 10.7270/Q2WS8SKS
					More data for this Ligand-Target Pair
Macrophage migration inhibitory factor (Homo sapiens (Human))	BDBM50186424 (CHEMBL377038 | US8618147, 2 | phenyl 2-(3-(4-hydro...) Show SMILES Oc1ccc(cc1)C1=NOC(CC(=O)Oc2ccccc2)C1 |t:8| Show InChI InChI=1S/C17H15NO4/c19-13-8-6-12(7-9-13)16-10-15(22-18-16)11-17(20)21-14-4-2-1-3-5-14/h1-9,15,19H,10-11H2	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Institute for Medical Research Curated by ChEMBL					Assay Description Inhibition of MIF tautomerase activity				Bioorg Med Chem Lett 16: 3376-9 (2006) Article DOI: 10.1016/j.bmcl.2006.04.038 BindingDB Entry DOI: 10.7270/Q27W6BSG
					More data for this Ligand-Target Pair
Macrophage migration inhibitory factor (Homo sapiens (Human))	BDBM50186432 (4-tert-butylphenyl 2-(3-(4-hydroxyphenyl)-4,5-dihy...) Show SMILES CC(C)(C)c1ccc(OC(=O)CC2CC(=NO2)c2ccc(O)cc2)cc1 |c:14| Show InChI InChI=1S/C21H23NO4/c1-21(2,3)15-6-10-17(11-7-15)25-20(24)13-18-12-19(22-26-18)14-4-8-16(23)9-5-14/h4-11,18,23H,12-13H2,1-3H3	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Institute for Medical Research Curated by ChEMBL					Assay Description Inhibition of MIF tautomerase activity				Bioorg Med Chem Lett 16: 3376-9 (2006) Article DOI: 10.1016/j.bmcl.2006.04.038 BindingDB Entry DOI: 10.7270/Q27W6BSG
					More data for this Ligand-Target Pair
Macrophage migration inhibitory factor (Homo sapiens (Human))	BDBM50209087 (CHEMBL221786 | benzyl-2-(4-hydroxybenzylidene)hydr...) Show SMILES Oc1ccc(C=NNC(=O)OCc2ccccc2)cc1 |w:5.4| Show InChI InChI=1S/C15H14N2O3/c18-14-8-6-12(7-9-14)10-16-17-15(19)20-11-13-4-2-1-3-5-13/h1-10,18H,11H2,(H,17,19)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
and The New York School of Medicine Curated by ChEMBL					Assay Description Inhibition of MIF tautomerase activity by spectrophotometric assay				J Med Chem 50: 1993-7 (2007) Article DOI: 10.1021/jm061477+ BindingDB Entry DOI: 10.7270/Q23X869D
					More data for this Ligand-Target Pair
Macrophage migration inhibitory factor (Mus musculus (Mouse))	BDBM50186426 (CHEMBL210858 | US10336721, ISO-1 | US10968198, ISO...) Show SMILES COC(=O)CC1CC(=NO1)c1ccc(O)cc1 |c:7| Show InChI InChI=1S/C12H13NO4/c1-16-12(15)7-10-6-11(13-17-10)8-2-4-9(14)5-3-8/h2-5,10,14H,6-7H2,1H3	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid PDB UniChem Patents Similars	PDB US Patent	n/a	n/a	1.10E+4	n/a	n/a	n/a	n/a	7.2	25
The Feinstein Institute for Medical Research US Patent					Assay Description MIF tautomerase activity was measured by UV-Visible recording spectrophotometry (SHIMADZU, UV1600U). A fresh stock solution of L-dopachrome methyl es...				US Patent US8618147 (2013) BindingDB Entry DOI: 10.7270/Q23R0RHZ
					More data for this Ligand-Target Pair				3D Structure (crystal)
Macrophage migration inhibitory factor (Homo sapiens (Human))	BDBM50186426 (CHEMBL210858 | US10336721, ISO-1 | US10968198, ISO...) Show SMILES COC(=O)CC1CC(=NO1)c1ccc(O)cc1 |c:7| Show InChI InChI=1S/C12H13NO4/c1-16-12(15)7-10-6-11(13-17-10)8-2-4-9(14)5-3-8/h2-5,10,14H,6-7H2,1H3	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid PDB UniChem Patents Similars	PDB Article PubMed	n/a	n/a	1.10E+4	n/a	n/a	n/a	n/a	n/a	n/a
Institute for Medical Research Curated by ChEMBL					Assay Description Inhibition of MIF tautomerase activity				Bioorg Med Chem Lett 16: 3376-9 (2006) Article DOI: 10.1016/j.bmcl.2006.04.038 BindingDB Entry DOI: 10.7270/Q27W6BSG
					More data for this Ligand-Target Pair				3D Structure (crystal)
Macrophage migration inhibitory factor (Homo sapiens (Human))	BDBM50373158 (CHEMBL402006) Show SMILES Oc1ccc(C=NOC(=O)C2CCC2)cc1 |w:5.4| Show InChI InChI=1S/C12H13NO3/c14-11-6-4-9(5-7-11)8-13-16-12(15)10-2-1-3-10/h4-8,10,14H,1-3H2	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.10E+4	n/a	n/a	n/a	n/a	n/a	n/a
Yale University Curated by ChEMBL					Assay Description Inhibition of MIF-mediated dopachrome tautomerase activity				J Biol Chem 282: 23089-95 (2007) Article DOI: 10.1074/jbc.M701825200 BindingDB Entry DOI: 10.7270/Q2KS6SD0
					More data for this Ligand-Target Pair
Macrophage migration inhibitory factor (Homo sapiens (Human))	BDBM50186442 (CHEMBL208658 | US8618147, 10 | ethyl 2-(3-(4-hydro...) Show SMILES CCOC(=O)CC1CC(=NO1)c1ccc(O)cc1 |c:8| Show InChI InChI=1S/C13H15NO4/c1-2-17-13(16)8-11-7-12(14-18-11)9-3-5-10(15)6-4-9/h3-6,11,15H,2,7-8H2,1H3	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.20E+4	n/a	n/a	n/a	n/a	n/a	n/a
Institute for Medical Research Curated by ChEMBL					Assay Description Inhibition of MIF tautomerase activity				Bioorg Med Chem Lett 16: 3376-9 (2006) Article DOI: 10.1016/j.bmcl.2006.04.038 BindingDB Entry DOI: 10.7270/Q27W6BSG
					More data for this Ligand-Target Pair
Macrophage migration inhibitory factor (Mus musculus (Mouse))	BDBM50186442 (CHEMBL208658 | US8618147, 10 | ethyl 2-(3-(4-hydro...) Show SMILES CCOC(=O)CC1CC(=NO1)c1ccc(O)cc1 |c:8| Show InChI InChI=1S/C13H15NO4/c1-2-17-13(16)8-11-7-12(14-18-11)9-3-5-10(15)6-4-9/h3-6,11,15H,2,7-8H2,1H3	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	US Patent	n/a	n/a	1.20E+4	n/a	n/a	n/a	n/a	7.2	25
The Feinstein Institute for Medical Research US Patent					Assay Description MIF tautomerase activity was measured by UV-Visible recording spectrophotometry (SHIMADZU, UV1600U). A fresh stock solution of L-dopachrome methyl es...				US Patent US8618147 (2013) BindingDB Entry DOI: 10.7270/Q23R0RHZ
					More data for this Ligand-Target Pair
Macrophage migration inhibitory factor (Homo sapiens (Human))	BDBM50186436 ((S)-methyl 2-(3-(4-hydroxyphenyl)-4,5-dihydroisoxa...) Show SMILES COC(=O)C[C@@H]1CC(=NO1)c1ccc(O)cc1 |c:7| Show InChI InChI=1S/C12H13NO4/c1-16-12(15)7-10-6-11(13-17-10)8-2-4-9(14)5-3-8/h2-5,10,14H,6-7H2,1H3/t10-/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.30E+4	n/a	n/a	n/a	n/a	n/a	n/a
Institute for Medical Research Curated by ChEMBL					Assay Description Inhibition of MIF tautomerase activity				Bioorg Med Chem Lett 16: 3376-9 (2006) Article DOI: 10.1016/j.bmcl.2006.04.038 BindingDB Entry DOI: 10.7270/Q27W6BSG
					More data for this Ligand-Target Pair

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