Found 7 hits with Last Name = 'alexander' and Initial = 'sp' Target/Host
(Institution) | Ligand | Target/Host
Links | Ligand
Links | Trg + Lig
Links | Ki
nM | ΔG°
kJ/mole | IC50
nM | Kd
nM | EC50/IC50
nM | koff
s-1 | kon
M-1s-1 | pH | Temp
°C |
|---|
Platelet-activating factor receptor
(Homo sapiens (Human)) | BDBM50422596
(CHEMBL371569)Show SMILES C[C@@H]1CCC2=C3CO[C@]2(O)[C@H]2O[C@]2(C)CC\C=C(C)\CC[C@]13C |c:18,t:4| Show InChI InChI=1S/C20H30O3/c1-13-6-5-10-19(4)17(23-19)20(21)15-8-7-14(2)18(3,11-9-13)16(15)12-22-20/h6,14,17,21H,5,7-12H2,1-4H3/b13-6+/t14-,17+,18+,19-,20+/m1/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet 
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 575 | n/a | n/a | n/a | n/a | n/a | n/a |
The University of Nottingham
Curated by ChEMBL
| Assay Description
Inhibition of [3H]PAF binding to platelet activating factor receptor in human platelet |
Bioorg Med Chem Lett 15: 3263-6 (2005)
Article DOI: 10.1016/j.bmcl.2005.04.048
BindingDB Entry DOI: 10.7270/Q2V12639 |
More data for this
Ligand-Target Pair | |
Platelet-activating factor receptor
(Homo sapiens (Human)) | BDBM50422594
(CHEMBL191612)Show SMILES C[C@@H]1CCC2=C3CO[C@]2(O)[C@@H]2O[C@@]2(C)CC\C=C(C)\CC[C@]13C |c:18,t:4| Show InChI InChI=1S/C20H30O3/c1-13-6-5-10-19(4)17(23-19)20(21)15-8-7-14(2)18(3,11-9-13)16(15)12-22-20/h6,14,17,21H,5,7-12H2,1-4H3/b13-6+/t14-,17-,18+,19+,20+/m1/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 575 | n/a | n/a | n/a | n/a | n/a | n/a |
The University of Nottingham
Curated by ChEMBL
| Assay Description
Inhibition of [3H]PAF binding to platelet activating factor receptor in human platelet |
Bioorg Med Chem Lett 15: 3263-6 (2005)
Article DOI: 10.1016/j.bmcl.2005.04.048
BindingDB Entry DOI: 10.7270/Q2V12639 |
More data for this
Ligand-Target Pair | |
Platelet-activating factor receptor
(Homo sapiens (Human)) | BDBM50422597
(CHEMBL371351)Show SMILES C[C@@H]1C[C@@H](O)C2=C3CO[C@]2(O)[C@@H]2O[C@@]2(C)CC\C=C(C)\CC[C@]13C |c:19,t:5| Show InChI InChI=1S/C20H30O4/c1-12-6-5-8-19(4)17(24-19)20(22)16-14(11-23-20)18(3,9-7-12)13(2)10-15(16)21/h6,13,15,17,21-22H,5,7-11H2,1-4H3/b12-6+/t13-,15-,17-,18+,19+,20+/m1/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 1.12E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
The University of Nottingham
Curated by ChEMBL
| Assay Description
Inhibition of [3H]PAF binding to platelet activating factor receptor in human platelet |
Bioorg Med Chem Lett 15: 3263-6 (2005)
Article DOI: 10.1016/j.bmcl.2005.04.048
BindingDB Entry DOI: 10.7270/Q2V12639 |
More data for this
Ligand-Target Pair | |
Platelet-activating factor receptor
(Homo sapiens (Human)) | BDBM50422595
(CHEMBL370068)Show SMILES C[C@@H]1CC[C@]23O[C@@]22CO[C@]3(O)\C=C(C)\CC\C=C(C)\CC[C@]12C |c:13,18| Show InChI InChI=1S/C20H30O3/c1-14-6-5-7-15(2)12-20(21)18-11-9-16(3)17(4,10-8-14)19(18,23-18)13-22-20/h6,12,16,21H,5,7-11,13H2,1-4H3/b14-6+,15-12+/t16-,17+,18+,19-,20-/m1/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 1.15E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
The University of Nottingham
Curated by ChEMBL
| Assay Description
Inhibition of [3H]PAF binding to platelet activating factor receptor in human platelet |
Bioorg Med Chem Lett 15: 3263-6 (2005)
Article DOI: 10.1016/j.bmcl.2005.04.048
BindingDB Entry DOI: 10.7270/Q2V12639 |
More data for this
Ligand-Target Pair | |
Platelet-activating factor receptor
(Homo sapiens (Human)) | BDBM50422599
(CHEMBL372012)Show SMILES C[C@@H]1C[C@H]2O[C@@]3(C)CC\C=C(C)\CC[C@@]1(C)C1=C2[C@](O)(OC1)[C@H]3O |c:9,17| Show InChI InChI=1S/C20H30O4/c1-12-6-5-8-19(4)17(21)20(22)16-14(11-23-20)18(3,9-7-12)13(2)10-15(16)24-19/h6,13,15,17,21-22H,5,7-11H2,1-4H3/b12-6+/t13-,15-,17+,18+,19+,20+/m1/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 1.26E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
The University of Nottingham
Curated by ChEMBL
| Assay Description
Inhibition of [3H]PAF binding to platelet activating factor receptor in human platelet |
Bioorg Med Chem Lett 15: 3263-6 (2005)
Article DOI: 10.1016/j.bmcl.2005.04.048
BindingDB Entry DOI: 10.7270/Q2V12639 |
More data for this
Ligand-Target Pair | |
Platelet-activating factor receptor
(Homo sapiens (Human)) | BDBM50422598
(CHEMBL365357)Show SMILES C[C@@H]1C[C@H](O)C2=C3CO[C@]2(O)[C@H]2O[C@]2(C)CC\C=C(C)\CC[C@]13C |c:19,t:5| Show InChI InChI=1S/C20H30O4/c1-12-6-5-8-19(4)17(24-19)20(22)16-14(11-23-20)18(3,9-7-12)13(2)10-15(16)21/h6,13,15,17,21-22H,5,7-11H2,1-4H3/b12-6+/t13-,15+,17+,18+,19-,20+/m1/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 1.45E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
The University of Nottingham
Curated by ChEMBL
| Assay Description
Inhibition of [3H]PAF binding to platelet activating factor receptor in human platelet |
Bioorg Med Chem Lett 15: 3263-6 (2005)
Article DOI: 10.1016/j.bmcl.2005.04.048
BindingDB Entry DOI: 10.7270/Q2V12639 |
More data for this
Ligand-Target Pair | |
Platelet-activating factor receptor
(Homo sapiens (Human)) | BDBM50422593
(CHEMBL363216)Show SMILES C[C@@H]1C[C@H]2O[C@@]3(C)CC\C=C(C)\CC[C@@]1(C)[C@]14CO[C@](O)([C@H]3O)[C@]21O4 |c:9| Show InChI InChI=1S/C20H30O5/c1-12-6-5-8-17(4)15(21)20(22)19-14(24-17)10-13(2)16(3,9-7-12)18(19,25-19)11-23-20/h6,13-15,21-22H,5,7-11H2,1-4H3/b12-6+/t13-,14-,15+,16+,17+,18-,19+,20-/m1/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 2.34E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
The University of Nottingham
Curated by ChEMBL
| Assay Description
Inhibition of [3H]PAF binding to platelet activating factor receptor in human platelet |
Bioorg Med Chem Lett 15: 3263-6 (2005)
Article DOI: 10.1016/j.bmcl.2005.04.048
BindingDB Entry DOI: 10.7270/Q2V12639 |
More data for this
Ligand-Target Pair | |
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