BindingDB PrimarySearch

Found 136 hits with Last Name = 'ali' and Initial = 'mr'
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Dual specificity protein phosphatase 5 [180-384] (Homo sapiens (Human))	BDBM50336799 (5,5',5''-[1,3,6-naphthalenetriyltris(sulfonylimino...) Show SMILES Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG PC cid PC sid PDB UniChem Patents Similars	Article PubMed	25	-43.4	4.40E+4	n/a	n/a	n/a	n/a	n/a	25
Texas Wesleyan University					Assay Description For the 96-well plate validation assay, sodium orthovanadate (Sigma Aldrich) was utilized as a positive control for inhibition [Swarup et al., Bioche...				BMC Biochem 16: 19 (2015) Article DOI: 10.1186/s12858-015-0048-3 BindingDB Entry DOI: 10.7270/Q26972FW
Texas Wesleyan University					More data for this Ligand-Target Pair
Acetylcholinesterase (Electrophorus electricus (Electric eel))	BDBM50406864 (CHEMBL4161244) Show SMILES Show InChI	UniProtKB/SwissProt GoogleScholar AffyNet	KEGG PC cid PC sid UniChem Similars	Article PubMed	6.91E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Tehran University of Medical Sciences Curated by ChEMBL					Assay Description Non-competitive inhibition of electric eel AChE using varying levels of acetylthiocholine iodide as substrate pretreated for 5 mins followed by subst...				Eur J Med Chem 152: 600-614 (2018) Article DOI: 10.1016/j.ejmech.2018.04.058 BindingDB Entry DOI: 10.7270/Q2WW7M8B
Tehran University of Medical Sciences Curated by ChEMBL					More data for this Ligand-Target Pair
Monoglyceride lipase (Homo sapiens (Human))	BDBM50065646 (CHEMBL3087181) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	<0.400	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of human MAGL				Citation and Details Article DOI: 10.1016/j.ejmech.2016.05.038 BindingDB Entry DOI: 10.7270/Q28056BZ
TBA					More data for this Ligand-Target Pair
Monoglyceride lipase (Homo sapiens (Human))	BDBM50242634 (5-((biphenyl-4-yl)methyl)-N,N-dimethyl-2H-tetrazol...) Show SMILES CN(C)C(=O)n1nnc(Cc2ccc(cc2)-c2ccccc2)n1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	0.900	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of MAGL (unknown origin)				Citation and Details Article DOI: 10.1016/j.ejmech.2016.05.038 BindingDB Entry DOI: 10.7270/Q28056BZ
TBA					More data for this Ligand-Target Pair
Monoglyceride lipase (Homo sapiens (Human))	BDBM179929 (US9133148, 1a) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	5.90	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of human MAGL transfected in human HEK293T cells assessed as reduction in ABPP binding by competitive binding assay				Citation and Details Article DOI: 10.1016/j.ejmech.2016.05.038 BindingDB Entry DOI: 10.7270/Q28056BZ
TBA					More data for this Ligand-Target Pair
Monoglyceride lipase (Homo sapiens (Human))	BDBM60622 (BDBM50300355 \| US11753371, Compound JZL-184 \| US91...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	6	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of MAGL (unknown origin)				Citation and Details Article DOI: 10.1016/j.ejmech.2016.05.038 BindingDB Entry DOI: 10.7270/Q28056BZ
TBA					More data for this Ligand-Target Pair
Monoglyceride lipase (Homo sapiens (Human))	BDBM50563791 (CHEMBL4778803) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	6.5	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of human MAGL using 4-Nitrophenylacetate as substrate				Citation and Details Article DOI: 10.1016/j.ejmech.2016.05.038 BindingDB Entry DOI: 10.7270/Q28056BZ
TBA					More data for this Ligand-Target Pair
Monoglyceride lipase (Homo sapiens (Human))	BDBM50563794 (CHEMBL4793668) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	8	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of human MAGL using 4-Nitrophenylacetate as substrate				Citation and Details Article DOI: 10.1016/j.ejmech.2016.05.038 BindingDB Entry DOI: 10.7270/Q28056BZ
TBA					More data for this Ligand-Target Pair
Monoglyceride lipase (Homo sapiens (Human))	BDBM50563792 (CHEMBL4788586) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	8	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of human MAGL using 4-Nitrophenylacetate as substrate				Citation and Details Article DOI: 10.1016/j.ejmech.2016.05.038 BindingDB Entry DOI: 10.7270/Q28056BZ
TBA					More data for this Ligand-Target Pair
Monoglyceride lipase (Homo sapiens (Human))	BDBM50563793 (CHEMBL4793997) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	9	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of human MAGL using 4-Nitrophenylacetate as substrate				Citation and Details Article DOI: 10.1016/j.ejmech.2016.05.038 BindingDB Entry DOI: 10.7270/Q28056BZ
TBA					More data for this Ligand-Target Pair
Monoglyceride lipase (Homo sapiens (Human))	BDBM50563790 (CHEMBL4780294) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	9	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of human MAGL using 4-Nitrophenylacetate as substrate				Citation and Details Article DOI: 10.1016/j.ejmech.2016.05.038 BindingDB Entry DOI: 10.7270/Q28056BZ
TBA					More data for this Ligand-Target Pair
Monoglyceride lipase (Homo sapiens (Human))	BDBM50563801 (CHEMBL4779678) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	16	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of human MAGL using 4-Nitrophenylacetate as substrate				Citation and Details Article DOI: 10.1016/j.ejmech.2016.05.038 BindingDB Entry DOI: 10.7270/Q28056BZ
TBA					More data for this Ligand-Target Pair
Monoglyceride lipase (Homo sapiens (Human))	BDBM50563802 (CHEMBL4793265) Show SMILES O=C(Cn1cncn1)Nc1ccc(cc1)-c1nc2ccccc2s1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	17	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of human MAGL using 4-Nitrophenylacetate as substrate				Citation and Details Article DOI: 10.1016/j.ejmech.2016.05.038 BindingDB Entry DOI: 10.7270/Q28056BZ
TBA					More data for this Ligand-Target Pair
Acetylcholinesterase (Electrophorus electricus (Electric eel))	BDBM8960 ((+/-)-2-[(1-benzylpiperidin-4-yl)methyl]-5,6-dimet...) Show SMILES Show InChI	UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	20	n/a	n/a	n/a	n/a	n/a	n/a
Tehran University of Medical Sciences Curated by ChEMBL					Assay Description Inhibition of electric eel AChE using acetylthiocholine iodide as substrate pretreated for 5 mins followed by substrate addition by Ellman's method				Eur J Med Chem 152: 600-614 (2018) Article DOI: 10.1016/j.ejmech.2018.04.058 BindingDB Entry DOI: 10.7270/Q2WW7M8B
Tehran University of Medical Sciences Curated by ChEMBL					More data for this Ligand-Target Pair
Monoglyceride lipase (Homo sapiens (Human))	BDBM50414921 (CHEMBL570812) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem	Article PubMed	n/a	n/a	20	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of MAGL (unknown origin)				Citation and Details Article DOI: 10.1016/j.ejmech.2016.05.038 BindingDB Entry DOI: 10.7270/Q28056BZ
TBA					More data for this Ligand-Target Pair
Monoglyceride lipase (Homo sapiens (Human))	BDBM50563803 (CHEMBL4797565) Show SMILES O=C(Cn1ccnc1)Nc1ccc(cc1)-c1nc2ccccc2s1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	22	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of human MAGL using 4-Nitrophenylacetate as substrate				Citation and Details Article DOI: 10.1016/j.ejmech.2016.05.038 BindingDB Entry DOI: 10.7270/Q28056BZ
TBA					More data for this Ligand-Target Pair
Xanthine dehydrogenase/oxidase (Bos taurus (Bovine))	BDBM50320491 (2-(3-CYANO-4-ISOBUTOXY-PHENYL)-4-METHYL-5-THIAZOLE...) Show SMILES CC(C)COc1ccc(cc1C#N)-c1nc(C)c(s1)C(O)=O Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase CHEMBL MCE MMDB PC cid PC sid PDB UniChem Patents	MMDB PDB Article PubMed	n/a	n/a	30	n/a	n/a	n/a	n/a	7.4	n/a
Jamia Hamdard					Assay Description Xanthine oxidase (XO) assay of 2-(benzylamino)-4-methyl-1,3-thiazole-5-carboxylic acid derivatives 5a-p was evaluated using Bovine milk XO (grade 1, ...				Chem Biol Drug Des 87: 508-16 (2016) Article DOI: 10.1111/cbdd.12686 BindingDB Entry DOI: 10.7270/Q24F1PHQ
Jamia Hamdard					More data for this Ligand-Target Pair				3D Structure (crystal)
Monoglyceride lipase (Homo sapiens (Human))	BDBM50563795 (CHEMBL4786239) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	68	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of human MAGL using 4-Nitrophenylacetate as substrate				Citation and Details Article DOI: 10.1016/j.ejmech.2016.05.038 BindingDB Entry DOI: 10.7270/Q28056BZ
TBA					More data for this Ligand-Target Pair
Monoglyceride lipase (Homo sapiens (Human))	BDBM50563785 (CHEMBL4792393) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	74	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of human MAGL using 4-Nitrophenylacetate as substrate				Citation and Details Article DOI: 10.1016/j.ejmech.2016.05.038 BindingDB Entry DOI: 10.7270/Q28056BZ
TBA					More data for this Ligand-Target Pair
Monoglyceride lipase (Homo sapiens (Human))	BDBM50432829 (CHEMBL2171700) Show SMILES COc1nn(-c2ccc(Oc3ccccc3)cc2)c(=O)o1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	78	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of MAGL (unknown origin)				Citation and Details Article DOI: 10.1016/j.ejmech.2016.05.038 BindingDB Entry DOI: 10.7270/Q28056BZ
TBA					More data for this Ligand-Target Pair
Monoglyceride lipase (Homo sapiens (Human))	BDBM50563809 (CHEMBL4794817) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	117	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of human MAGL using 4-Nitrophenylacetate as substrate				Citation and Details Article DOI: 10.1016/j.ejmech.2016.05.038 BindingDB Entry DOI: 10.7270/Q28056BZ
TBA					More data for this Ligand-Target Pair
Monoglyceride lipase (Homo sapiens (Human))	BDBM50563797 (CHEMBL4777523) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	151	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of human MAGL using 4-Nitrophenylacetate as substrate				Citation and Details Article DOI: 10.1016/j.ejmech.2016.05.038 BindingDB Entry DOI: 10.7270/Q28056BZ
TBA					More data for this Ligand-Target Pair
Monoglyceride lipase (Homo sapiens (Human))	BDBM50563808 (CHEMBL4793077) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	196	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of human MAGL using 4-Nitrophenylacetate as substrate				Citation and Details Article DOI: 10.1016/j.ejmech.2016.05.038 BindingDB Entry DOI: 10.7270/Q28056BZ
TBA					More data for this Ligand-Target Pair
Monoglyceride lipase (Homo sapiens (Human))	BDBM50563796 (CHEMBL4780477) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	242	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of human MAGL using 4-Nitrophenylacetate as substrate				Citation and Details Article DOI: 10.1016/j.ejmech.2016.05.038 BindingDB Entry DOI: 10.7270/Q28056BZ
TBA					More data for this Ligand-Target Pair
Monoglyceride lipase (Homo sapiens (Human))	BDBM50563800 (CHEMBL4776276) Show SMILES O=C(CN1CCCCC1)Nc1ccc(cc1)-c1nc2ccccc2s1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	282	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of human MAGL using 4-Nitrophenylacetate as substrate				Citation and Details Article DOI: 10.1016/j.ejmech.2016.05.038 BindingDB Entry DOI: 10.7270/Q28056BZ
TBA					More data for this Ligand-Target Pair
Monoglyceride lipase (Homo sapiens (Human))	BDBM50414921 (CHEMBL570812) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem	Article PubMed	n/a	n/a	424	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of human MAGL using 4-Nitrophenylacetate as substrate				Citation and Details Article DOI: 10.1016/j.ejmech.2016.05.038 BindingDB Entry DOI: 10.7270/Q28056BZ
TBA					More data for this Ligand-Target Pair
Monoglyceride lipase (Homo sapiens (Human))	BDBM50563799 (CHEMBL4785038) Show SMILES O=C(CN1CCOCC1)Nc1ccc(cc1)-c1nc2ccccc2s1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	780	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of human MAGL using 4-Nitrophenylacetate as substrate				Citation and Details Article DOI: 10.1016/j.ejmech.2016.05.038 BindingDB Entry DOI: 10.7270/Q28056BZ
TBA					More data for this Ligand-Target Pair
Monoglyceride lipase (Homo sapiens (Human))	BDBM50563798 (CHEMBL4800406) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	815	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of human MAGL using 4-Nitrophenylacetate as substrate				Citation and Details Article DOI: 10.1016/j.ejmech.2016.05.038 BindingDB Entry DOI: 10.7270/Q28056BZ
TBA					More data for this Ligand-Target Pair
Tyrosine-protein phosphatase non-receptor type 11 (Homo sapiens (Human))	BDBM231697 (RR601) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.10E+3	n/a	n/a	n/a	n/a	7.0	25
Concordia University of Wisconsin					Assay Description Assays with and without inhibitor were performed in Corning 96-well clear bottom plates having a nonbinding surface, with a total assay volume of 200...				BMC Biochem 18: 10 (2017) Article DOI: 10.1186/s12858-017-0083-3 BindingDB Entry DOI: 10.7270/Q2JW8CSF
Concordia University of Wisconsin					More data for this Ligand-Target Pair
Dual specificity protein phosphatase 5 (Homo sapiens (Human))	BDBM231694 (1-Amin-5-Naphthol-7-Sulfonic acid \| NCI2602 \| RR53...) Show SMILES Nc1cccc2c(O)cc(cc12)S(O)(=O)=O Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.70E+3	n/a	n/a	n/a	n/a	n/a	n/a
Concordia University of Wisconsin					Assay Description This assay was done with full-length protein (containing both domains), andusing pERK as substrate.				BMC Biochem 18: 10 (2017) Article DOI: 10.1186/s12858-017-0083-3 BindingDB Entry DOI: 10.7270/Q2JW8CSF
Concordia University of Wisconsin					More data for this Ligand-Target Pair
Tyrosine-protein phosphatase non-receptor type 1 (Homo sapiens (Human))	BDBM231697 (RR601) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	2.10E+3	n/a	n/a	n/a	n/a	7.0	25
Concordia University of Wisconsin					Assay Description Assays with and without inhibitor were performed in Corning 96-well clear bottom plates having a nonbinding surface, with a total assay volume of 200...				BMC Biochem 18: 10 (2017) Article DOI: 10.1186/s12858-017-0083-3 BindingDB Entry DOI: 10.7270/Q2JW8CSF
Concordia University of Wisconsin					More data for this Ligand-Target Pair
Monoglyceride lipase (Homo sapiens (Human))	BDBM50563788 (CHEMBL4798413) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	3.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of human MAGL using 4-Nitrophenylacetate as substrate				Citation and Details Article DOI: 10.1016/j.ejmech.2016.05.038 BindingDB Entry DOI: 10.7270/Q28056BZ
TBA					More data for this Ligand-Target Pair
Dual specificity protein phosphatase 5 (Homo sapiens (Human))	BDBM231694 (1-Amin-5-Naphthol-7-Sulfonic acid \| NCI2602 \| RR53...) Show SMILES Nc1cccc2c(O)cc(cc12)S(O)(=O)=O Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem	Article PubMed	n/a	n/a	3.30E+3	n/a	n/a	n/a	n/a	7.5	25
Concordia University of Wisconsin					Assay Description Upon the addition of 4 μL of these respective inhibitor stock solutions to the assay buffer, the resulting range in assay inhibitor concentratio...				BMC Biochem 18: 10 (2017) Article DOI: 10.1186/s12858-017-0083-3 BindingDB Entry DOI: 10.7270/Q2JW8CSF
Concordia University of Wisconsin					More data for this Ligand-Target Pair
Cholinesterase (Equus caballus (Horse))	BDBM8960 ((+/-)-2-[(1-benzylpiperidin-4-yl)methyl]-5,6-dimet...) Show SMILES Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	3.40E+3	n/a	n/a	n/a	n/a	n/a	n/a
Tehran University of Medical Sciences Curated by ChEMBL					Assay Description Inhibition of equine serum BuChE using butyrylthiocholine iodide as substrate pretreated for 5 mins followed by substrate addition by Ellman's method				Eur J Med Chem 152: 600-614 (2018) Article DOI: 10.1016/j.ejmech.2018.04.058 BindingDB Entry DOI: 10.7270/Q2WW7M8B
Tehran University of Medical Sciences Curated by ChEMBL					More data for this Ligand-Target Pair
Xanthine dehydrogenase/oxidase (Bos taurus (Bovine))	BDBM178040 (4-methyl-2-{[(2-methylphenyl)methyl]amino}-1,3-thi...) Show SMILES Cc1nc(NCc2ccccc2C)sc1C(O)=O Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.60E+3	n/a	n/a	n/a	n/a	7.4	n/a
Jamia Hamdard					Assay Description Xanthine oxidase (XO) assay of 2-(benzylamino)-4-methyl-1,3-thiazole-5-carboxylic acid derivatives 5a-p was evaluated using Bovine milk XO (grade 1, ...				Chem Biol Drug Des 87: 508-16 (2016) Article DOI: 10.1111/cbdd.12686 BindingDB Entry DOI: 10.7270/Q24F1PHQ
Jamia Hamdard					More data for this Ligand-Target Pair
Dual specificity protein phosphatase 5 (Homo sapiens (Human))	BDBM231697 (RR601) Show SMILES Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	4.80E+3	n/a	n/a	n/a	n/a	n/a	n/a
Concordia University of Wisconsin					Assay Description This assay was done with full-length protein (containing both domains), andusing pERK as substrate.				BMC Biochem 18: 10 (2017) Article DOI: 10.1186/s12858-017-0083-3 BindingDB Entry DOI: 10.7270/Q2JW8CSF
Concordia University of Wisconsin					More data for this Ligand-Target Pair
Dual specificity protein phosphatase 5 (Homo sapiens (Human))	BDBM231694 (1-Amin-5-Naphthol-7-Sulfonic acid \| NCI2602 \| RR53...) Show SMILES Nc1cccc2c(O)cc(cc12)S(O)(=O)=O Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem	Article PubMed	n/a	n/a	5.90E+3	n/a	n/a	n/a	n/a	7.5	25
Concordia University of Wisconsin					Assay Description Upon the addition of 4 μL of these respective inhibitor stock solutions to the assay buffer, the resulting range in assay inhibitor concentratio...				BMC Biochem 18: 10 (2017) Article DOI: 10.1186/s12858-017-0083-3 BindingDB Entry DOI: 10.7270/Q2JW8CSF
Concordia University of Wisconsin					More data for this Ligand-Target Pair
Dual specificity protein phosphatase 5 (Homo sapiens (Human))	BDBM231694 (1-Amin-5-Naphthol-7-Sulfonic acid \| NCI2602 \| RR53...) Show SMILES Nc1cccc2c(O)cc(cc12)S(O)(=O)=O Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem	Article PubMed	n/a	n/a	6.30E+3	n/a	n/a	n/a	n/a	7.5	25
Concordia University of Wisconsin					Assay Description Upon the addition of 4 μL of these respective inhibitor stock solutions to the assay buffer, the resulting range in assay inhibitor concentratio...				BMC Biochem 18: 10 (2017) Article DOI: 10.1186/s12858-017-0083-3 BindingDB Entry DOI: 10.7270/Q2JW8CSF
Concordia University of Wisconsin					More data for this Ligand-Target Pair
Monoglyceride lipase (Homo sapiens (Human))	BDBM50563787 (CHEMBL4788417) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	6.50E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of human MAGL using 4-Nitrophenylacetate as substrate				Citation and Details Article DOI: 10.1016/j.ejmech.2016.05.038 BindingDB Entry DOI: 10.7270/Q28056BZ
TBA					More data for this Ligand-Target Pair
Cholinesterase (Equus caballus (Horse))	BDBM50406848 (CHEMBL4160630) Show SMILES Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	KEGG PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	7.80E+3	n/a	n/a	n/a	n/a	n/a	n/a
Tehran University of Medical Sciences Curated by ChEMBL					Assay Description Inhibition of equine serum BuChE using butyrylthiocholine iodide as substrate pretreated for 5 mins followed by substrate addition by Ellman's method				Eur J Med Chem 152: 600-614 (2018) Article DOI: 10.1016/j.ejmech.2018.04.058 BindingDB Entry DOI: 10.7270/Q2WW7M8B
Tehran University of Medical Sciences Curated by ChEMBL					More data for this Ligand-Target Pair
Xanthine dehydrogenase/oxidase (Bos taurus (Bovine))	BDBM178041 (2-{[(2,4-dichlorophenyl)methyl]amino}-4-methyl-1,3...) Show SMILES Cc1nc(NCc2ccc(Cl)cc2Cl)sc1C(O)=O Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	8.10E+3	n/a	n/a	n/a	n/a	7.4	n/a
Jamia Hamdard					Assay Description Xanthine oxidase (XO) assay of 2-(benzylamino)-4-methyl-1,3-thiazole-5-carboxylic acid derivatives 5a-p was evaluated using Bovine milk XO (grade 1, ...				Chem Biol Drug Des 87: 508-16 (2016) Article DOI: 10.1111/cbdd.12686 BindingDB Entry DOI: 10.7270/Q24F1PHQ
Jamia Hamdard					More data for this Ligand-Target Pair
Xanthine dehydrogenase/oxidase (Bos taurus (Bovine))	BDBM178039 (2-{[(2-chlorophenyl)methyl]amino}-4-methyl-1,3-thi...) Show SMILES Cc1nc(NCc2ccccc2Cl)sc1C(O)=O Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	9.90E+3	n/a	n/a	n/a	n/a	7.4	n/a
Jamia Hamdard					Assay Description Xanthine oxidase (XO) assay of 2-(benzylamino)-4-methyl-1,3-thiazole-5-carboxylic acid derivatives 5a-p was evaluated using Bovine milk XO (grade 1, ...				Chem Biol Drug Des 87: 508-16 (2016) Article DOI: 10.1111/cbdd.12686 BindingDB Entry DOI: 10.7270/Q24F1PHQ
Jamia Hamdard					More data for this Ligand-Target Pair
Cholinesterase (Equus caballus (Horse))	BDBM50406860 (CHEMBL4159985) Show SMILES Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	KEGG PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.03E+4	n/a	n/a	n/a	n/a	n/a	n/a
Tehran University of Medical Sciences Curated by ChEMBL					Assay Description Inhibition of equine serum BuChE using butyrylthiocholine iodide as substrate pretreated for 5 mins followed by substrate addition by Ellman's method				Eur J Med Chem 152: 600-614 (2018) Article DOI: 10.1016/j.ejmech.2018.04.058 BindingDB Entry DOI: 10.7270/Q2WW7M8B
Tehran University of Medical Sciences Curated by ChEMBL					More data for this Ligand-Target Pair
Monoglyceride lipase (Homo sapiens (Human))	BDBM50563786 (CHEMBL4783652) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.30E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of human MAGL using 4-Nitrophenylacetate as substrate				Citation and Details Article DOI: 10.1016/j.ejmech.2016.05.038 BindingDB Entry DOI: 10.7270/Q28056BZ
TBA					More data for this Ligand-Target Pair
Xanthine dehydrogenase/oxidase (Bos taurus (Bovine))	BDBM178043 (2-{[(2-methoxyphenyl)methyl]amino}-4-methyl-1,3-th...) Show SMILES COc1ccccc1CNc1nc(C)c(s1)C(O)=O Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.47E+4	n/a	n/a	n/a	n/a	7.4	n/a
Jamia Hamdard					Assay Description Xanthine oxidase (XO) assay of 2-(benzylamino)-4-methyl-1,3-thiazole-5-carboxylic acid derivatives 5a-p was evaluated using Bovine milk XO (grade 1, ...				Chem Biol Drug Des 87: 508-16 (2016) Article DOI: 10.1111/cbdd.12686 BindingDB Entry DOI: 10.7270/Q24F1PHQ
Jamia Hamdard					More data for this Ligand-Target Pair
Acetylcholinesterase (Electrophorus electricus (Electric eel))	BDBM50406864 (CHEMBL4161244) Show SMILES Show InChI	UniProtKB/SwissProt GoogleScholar AffyNet	KEGG PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.64E+4	n/a	n/a	n/a	n/a	n/a	n/a
Tehran University of Medical Sciences Curated by ChEMBL					Assay Description Inhibition of electric eel AChE using acetylthiocholine iodide as substrate pretreated for 5 mins followed by substrate addition by Ellman's method				Eur J Med Chem 152: 600-614 (2018) Article DOI: 10.1016/j.ejmech.2018.04.058 BindingDB Entry DOI: 10.7270/Q2WW7M8B
Tehran University of Medical Sciences Curated by ChEMBL					More data for this Ligand-Target Pair
Dual specificity protein phosphatase 5 (Homo sapiens (Human))	BDBM231694 (1-Amin-5-Naphthol-7-Sulfonic acid \| NCI2602 \| RR53...) Show SMILES Nc1cccc2c(O)cc(cc12)S(O)(=O)=O Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.65E+4	n/a	n/a	n/a	n/a	7.5	25
Concordia University of Wisconsin					Assay Description Upon the addition of 4 μL of these respective inhibitor stock solutions to the assay buffer, the resulting range in assay inhibitor concentratio...				BMC Biochem 18: 10 (2017) Article DOI: 10.1186/s12858-017-0083-3 BindingDB Entry DOI: 10.7270/Q2JW8CSF
Concordia University of Wisconsin					More data for this Ligand-Target Pair
Xanthine dehydrogenase/oxidase (Bos taurus (Bovine))	BDBM178036 (2-{[(4-hydroxyphenyl)methyl]amino}-4-methyl-1,3-th...) Show SMILES Cc1nc(NCc2ccc(O)cc2)sc1C(O)=O Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.15E+4	n/a	n/a	n/a	n/a	7.4	n/a
Jamia Hamdard					Assay Description Xanthine oxidase (XO) assay of 2-(benzylamino)-4-methyl-1,3-thiazole-5-carboxylic acid derivatives 5a-p was evaluated using Bovine milk XO (grade 1, ...				Chem Biol Drug Des 87: 508-16 (2016) Article DOI: 10.1111/cbdd.12686 BindingDB Entry DOI: 10.7270/Q24F1PHQ
Jamia Hamdard					More data for this Ligand-Target Pair
Dual specificity protein phosphatase 5 (Homo sapiens (Human))	BDBM231694 (1-Amin-5-Naphthol-7-Sulfonic acid \| NCI2602 \| RR53...) Show SMILES Nc1cccc2c(O)cc(cc12)S(O)(=O)=O Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem	Article PubMed	n/a	n/a	2.28E+4	n/a	n/a	n/a	n/a	n/a	n/a
Concordia University of Wisconsin					Assay Description This assay was done with full-length protein (containing both domains), andusing pERK as substrate.				BMC Biochem 18: 10 (2017) Article DOI: 10.1186/s12858-017-0083-3 BindingDB Entry DOI: 10.7270/Q2JW8CSF
Concordia University of Wisconsin					More data for this Ligand-Target Pair
Monoglyceride lipase (Homo sapiens (Human))	BDBM50563782 (CHEMBL4786879) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	2.40E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of human MAGL using 4-Nitrophenylacetate as substrate				Citation and Details Article DOI: 10.1016/j.ejmech.2016.05.038 BindingDB Entry DOI: 10.7270/Q28056BZ
TBA					More data for this Ligand-Target Pair

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