Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Cannabinoid receptor 2 (Homo sapiens (Human)) | BDBM21281 ((11R)-2-methyl-11-(morpholin-4-ylmethyl)-3-(naphth...) | PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL MCE PC cid PC sid PDB UniChem Patents Similars | PDB Article PubMed | 0.900 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of California Berkeley Curated by ChEMBL | Assay Description Displacement of [3H]-CP55940 from human recombinant CB2 receptor expressed in HEK293 cells after 90 mins by scintillation counting analysis | J Nat Prod 78: 1671-82 (2015) Article DOI: 10.1021/acs.jnatprod.5b00301 BindingDB Entry DOI: 10.7270/Q22F7Q76 | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (crystal) | ||||||||||||
Cannabinoid receptor 1 (Homo sapiens (Human)) | BDBM21281 ((11R)-2-methyl-11-(morpholin-4-ylmethyl)-3-(naphth...) | PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL MCE PC cid PC sid PDB UniChem Patents Similars | Article PubMed | 8.80 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of California Berkeley Curated by ChEMBL | Assay Description Displacement of [3H]-CP55940 from human recombinant CB1 receptor expressed in HEK293 cells after 90 mins by scintillation counting analysis | J Nat Prod 78: 1671-82 (2015) Article DOI: 10.1021/acs.jnatprod.5b00301 BindingDB Entry DOI: 10.7270/Q22F7Q76 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Proteasome subunit beta type-5 (Homo sapiens (Human)) | BDBM50257325 (CHEMBL4090056) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | 375 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Department of Pediatrics, School of Medicine, University of California, San Diego , La Jolla, California 92093, United States. Curated by ChEMBL | Assay Description Irreversible inhibition of human 20S proteasome beta5 subunit using suc-LLVY-AMC as substrate after 4 hrs at 30 mins time interval by fluorescence as... | J Med Chem 60: 6721-6732 (2017) Article DOI: 10.1021/acs.jmedchem.7b00671 BindingDB Entry DOI: 10.7270/Q2CR5WSK | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cannabinoid receptor 1 (Homo sapiens (Human)) | BDBM50108987 (CHEMBL3597331) | PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 410 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of California Berkeley Curated by ChEMBL | Assay Description Displacement of [3H]-CP55940 from human recombinant CB1 receptor expressed in HEK293 cells after 90 mins by scintillation counting analysis | J Nat Prod 78: 1671-82 (2015) Article DOI: 10.1021/acs.jnatprod.5b00301 BindingDB Entry DOI: 10.7270/Q22F7Q76 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cannabinoid receptor 1 (Homo sapiens (Human)) | BDBM50108989 (CHEMBL3597332) | PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 470 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of California Berkeley Curated by ChEMBL | Assay Description Displacement of [3H]-CP55940 from human recombinant CB1 receptor expressed in HEK293 cells after 90 mins by scintillation counting analysis | J Nat Prod 78: 1671-82 (2015) Article DOI: 10.1021/acs.jnatprod.5b00301 BindingDB Entry DOI: 10.7270/Q22F7Q76 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cannabinoid receptor 1 (Homo sapiens (Human)) | BDBM50108988 (CHEMBL3597330) | PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 590 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of California Berkeley Curated by ChEMBL | Assay Description Displacement of [3H]-CP55940 from human recombinant CB1 receptor expressed in HEK293 cells after 90 mins by scintillation counting analysis | J Nat Prod 78: 1671-82 (2015) Article DOI: 10.1021/acs.jnatprod.5b00301 BindingDB Entry DOI: 10.7270/Q22F7Q76 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cannabinoid receptor 2 (Homo sapiens (Human)) | BDBM50108987 (CHEMBL3597331) | PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 860 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of California Berkeley Curated by ChEMBL | Assay Description Displacement of [3H]-CP55940 from human recombinant CB2 receptor expressed in HEK293 cells after 90 mins by scintillation counting analysis | J Nat Prod 78: 1671-82 (2015) Article DOI: 10.1021/acs.jnatprod.5b00301 BindingDB Entry DOI: 10.7270/Q22F7Q76 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cannabinoid receptor 2 (Homo sapiens (Human)) | BDBM50108988 (CHEMBL3597330) | PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 1.03E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of California Berkeley Curated by ChEMBL | Assay Description Displacement of [3H]-CP55940 from human recombinant CB2 receptor expressed in HEK293 cells after 90 mins by scintillation counting analysis | J Nat Prod 78: 1671-82 (2015) Article DOI: 10.1021/acs.jnatprod.5b00301 BindingDB Entry DOI: 10.7270/Q22F7Q76 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Proteasome subunit beta type-5 (Homo sapiens (Human)) | BDBM50257327 (CHEMBL4067938) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | 3.74E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Department of Pediatrics, School of Medicine, University of California, San Diego , La Jolla, California 92093, United States. Curated by ChEMBL | Assay Description Irreversible inhibition of human 20S proteasome beta5 subunit using suc-LLVY-AMC as substrate after 4 hrs at 30 mins time interval by fluorescence as... | J Med Chem 60: 6721-6732 (2017) Article DOI: 10.1021/acs.jmedchem.7b00671 BindingDB Entry DOI: 10.7270/Q2CR5WSK | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Proteasome subunit beta type-5 (Homo sapiens (Human)) | BDBM50257326 (CHEMBL4086345) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | 3.92E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Department of Pediatrics, School of Medicine, University of California, San Diego , La Jolla, California 92093, United States. Curated by ChEMBL | Assay Description Irreversible inhibition of human 20S proteasome beta5 subunit using suc-LLVY-AMC as substrate after 4 hrs at 30 mins time interval by fluorescence as... | J Med Chem 60: 6721-6732 (2017) Article DOI: 10.1021/acs.jmedchem.7b00671 BindingDB Entry DOI: 10.7270/Q2CR5WSK | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Procathepsin L (Homo sapiens (Human)) | BDBM50505559 (CHEMBL4441303) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 0.0940 | n/a | n/a | n/a | n/a | n/a | n/a |
The University of Jordan Curated by ChEMBL | Assay Description Inhibition of human cathepsin L using fluorogenic substrate cbz-FR-AMC monitored for 90 to 120 mins by spectrophotometry | J Med Chem 62: 9026-9044 (2019) Article DOI: 10.1021/acs.jmedchem.9b00294 BindingDB Entry DOI: 10.7270/Q2H998GC | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cruzipain (Trypanosoma cruzi) | BDBM50505555 (CHEMBL4447348) | PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 0.25 | n/a | n/a | n/a | n/a | n/a | n/a |
The University of Jordan Curated by ChEMBL | Assay Description Inhibition of recombinant Trypanosoma cruzi Cruzain expressed in Pichia pastoris using Z-Phe-Arg-AMC substrate incubated for 30 mins by fluorescence ... | J Med Chem 62: 9026-9044 (2019) Article DOI: 10.1021/acs.jmedchem.9b00294 BindingDB Entry DOI: 10.7270/Q2H998GC | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cruzipain (Trypanosoma cruzi) | BDBM50033762 (Gallinamide A) | PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | Purchase MCE PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 0.260 | n/a | n/a | n/a | n/a | n/a | n/a |
The University of Jordan Curated by ChEMBL | Assay Description Inhibition of recombinant Trypanosoma cruzi Cruzain expressed in Pichia pastoris using Z-Phe-Arg-AMC substrate incubated for 30 mins by fluorescence ... | J Med Chem 62: 9026-9044 (2019) Article DOI: 10.1021/acs.jmedchem.9b00294 BindingDB Entry DOI: 10.7270/Q2H998GC | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cruzipain (Trypanosoma cruzi) | BDBM50505557 (CHEMBL4527930) | PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 0.470 | n/a | n/a | n/a | n/a | n/a | n/a |
The University of Jordan Curated by ChEMBL | Assay Description Inhibition of recombinant Trypanosoma cruzi Cruzain expressed in Pichia pastoris using Z-Phe-Arg-AMC substrate incubated for 30 mins by fluorescence ... | J Med Chem 62: 9026-9044 (2019) Article DOI: 10.1021/acs.jmedchem.9b00294 BindingDB Entry DOI: 10.7270/Q2H998GC | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cruzipain (Trypanosoma cruzi) | BDBM50505568 (CHEMBL4482954) | PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 0.490 | n/a | n/a | n/a | n/a | n/a | n/a |
The University of Jordan Curated by ChEMBL | Assay Description Inhibition of recombinant Trypanosoma cruzi Cruzain expressed in Pichia pastoris using Z-Phe-Arg-AMC substrate incubated for 30 mins by fluorescence ... | J Med Chem 62: 9026-9044 (2019) Article DOI: 10.1021/acs.jmedchem.9b00294 BindingDB Entry DOI: 10.7270/Q2H998GC | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Procathepsin L (Homo sapiens (Human)) | BDBM50505555 (CHEMBL4447348) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 0.632 | n/a | n/a | n/a | n/a | n/a | n/a |
The University of Jordan Curated by ChEMBL | Assay Description Inhibition of human cathepsin L using fluorogenic substrate cbz-FR-AMC monitored for 90 to 120 mins by spectrophotometry | J Med Chem 62: 9026-9044 (2019) Article DOI: 10.1021/acs.jmedchem.9b00294 BindingDB Entry DOI: 10.7270/Q2H998GC | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cruzipain (Trypanosoma cruzi) | BDBM50505562 (CHEMBL4445744) | PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 0.730 | n/a | n/a | n/a | n/a | n/a | n/a |
The University of Jordan Curated by ChEMBL | Assay Description Inhibition of recombinant Trypanosoma cruzi Cruzain expressed in Pichia pastoris using Z-Phe-Arg-AMC substrate incubated for 30 mins by fluorescence ... | J Med Chem 62: 9026-9044 (2019) Article DOI: 10.1021/acs.jmedchem.9b00294 BindingDB Entry DOI: 10.7270/Q2H998GC | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cruzipain (Trypanosoma cruzi) | BDBM50505554 (CHEMBL4564747) | PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 0.760 | n/a | n/a | n/a | n/a | n/a | n/a |
The University of Jordan Curated by ChEMBL | Assay Description Inhibition of recombinant Trypanosoma cruzi Cruzain expressed in Pichia pastoris using Z-Phe-Arg-AMC substrate incubated for 30 mins by fluorescence ... | J Med Chem 62: 9026-9044 (2019) Article DOI: 10.1021/acs.jmedchem.9b00294 BindingDB Entry DOI: 10.7270/Q2H998GC | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Procathepsin L (Homo sapiens (Human)) | BDBM50505557 (CHEMBL4527930) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 0.790 | n/a | n/a | n/a | n/a | n/a | n/a |
The University of Jordan Curated by ChEMBL | Assay Description Inhibition of human cathepsin L using fluorogenic substrate cbz-FR-AMC monitored for 90 to 120 mins by spectrophotometry | J Med Chem 62: 9026-9044 (2019) Article DOI: 10.1021/acs.jmedchem.9b00294 BindingDB Entry DOI: 10.7270/Q2H998GC | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cruzipain (Trypanosoma cruzi) | BDBM50505563 (CHEMBL4527329) | PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 0.840 | n/a | n/a | n/a | n/a | n/a | n/a |
The University of Jordan Curated by ChEMBL | Assay Description Inhibition of recombinant Trypanosoma cruzi Cruzain expressed in Pichia pastoris using Z-Phe-Arg-AMC substrate incubated for 30 mins by fluorescence ... | J Med Chem 62: 9026-9044 (2019) Article DOI: 10.1021/acs.jmedchem.9b00294 BindingDB Entry DOI: 10.7270/Q2H998GC | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Procathepsin L (Homo sapiens (Human)) | BDBM50505566 (CHEMBL4582558) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 1 | n/a | n/a | n/a | n/a | n/a | n/a |
The University of Jordan Curated by ChEMBL | Assay Description Inhibition of human cathepsin L using fluorogenic substrate cbz-FR-AMC monitored for 90 to 120 mins by spectrophotometry | J Med Chem 62: 9026-9044 (2019) Article DOI: 10.1021/acs.jmedchem.9b00294 BindingDB Entry DOI: 10.7270/Q2H998GC | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cruzipain (Trypanosoma cruzi) | BDBM50505565 (CHEMBL4474668) | PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 1.10 | n/a | n/a | n/a | n/a | n/a | n/a |
The University of Jordan Curated by ChEMBL | Assay Description Inhibition of recombinant Trypanosoma cruzi Cruzain expressed in Pichia pastoris using Z-Phe-Arg-AMC substrate incubated for 30 mins by fluorescence ... | J Med Chem 62: 9026-9044 (2019) Article DOI: 10.1021/acs.jmedchem.9b00294 BindingDB Entry DOI: 10.7270/Q2H998GC | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cruzipain (Trypanosoma cruzi) | BDBM50505559 (CHEMBL4441303) | PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 1.10 | n/a | n/a | n/a | n/a | n/a | n/a |
The University of Jordan Curated by ChEMBL | Assay Description Inhibition of recombinant Trypanosoma cruzi Cruzain expressed in Pichia pastoris using Z-Phe-Arg-AMC substrate incubated for 30 mins by fluorescence ... | J Med Chem 62: 9026-9044 (2019) Article DOI: 10.1021/acs.jmedchem.9b00294 BindingDB Entry DOI: 10.7270/Q2H998GC | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cruzipain (Trypanosoma cruzi) | BDBM50505564 (CHEMBL4527867) | PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 1.20 | n/a | n/a | n/a | n/a | n/a | n/a |
The University of Jordan Curated by ChEMBL | Assay Description Inhibition of recombinant Trypanosoma cruzi Cruzain expressed in Pichia pastoris using Z-Phe-Arg-AMC substrate incubated for 30 mins by fluorescence ... | J Med Chem 62: 9026-9044 (2019) Article DOI: 10.1021/acs.jmedchem.9b00294 BindingDB Entry DOI: 10.7270/Q2H998GC | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cruzipain (Trypanosoma cruzi) | BDBM50505561 (CHEMBL4475810) | PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 1.20 | n/a | n/a | n/a | n/a | n/a | n/a |
The University of Jordan Curated by ChEMBL | Assay Description Inhibition of recombinant Trypanosoma cruzi Cruzain expressed in Pichia pastoris using Z-Phe-Arg-AMC substrate incubated for 30 mins by fluorescence ... | J Med Chem 62: 9026-9044 (2019) Article DOI: 10.1021/acs.jmedchem.9b00294 BindingDB Entry DOI: 10.7270/Q2H998GC | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Procathepsin L (Homo sapiens (Human)) | BDBM50505560 (CHEMBL4471760) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 1.30 | n/a | n/a | n/a | n/a | n/a | n/a |
The University of Jordan Curated by ChEMBL | Assay Description Inhibition of human cathepsin L using fluorogenic substrate cbz-FR-AMC monitored for 90 to 120 mins by spectrophotometry | J Med Chem 62: 9026-9044 (2019) Article DOI: 10.1021/acs.jmedchem.9b00294 BindingDB Entry DOI: 10.7270/Q2H998GC | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cruzipain (Trypanosoma cruzi) | BDBM50505560 (CHEMBL4471760) | PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 1.40 | n/a | n/a | n/a | n/a | n/a | n/a |
The University of Jordan Curated by ChEMBL | Assay Description Inhibition of recombinant Trypanosoma cruzi Cruzain expressed in Pichia pastoris using Z-Phe-Arg-AMC substrate incubated for 30 mins by fluorescence ... | J Med Chem 62: 9026-9044 (2019) Article DOI: 10.1021/acs.jmedchem.9b00294 BindingDB Entry DOI: 10.7270/Q2H998GC | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Procathepsin L (Homo sapiens (Human)) | BDBM50505562 (CHEMBL4445744) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 1.40 | n/a | n/a | n/a | n/a | n/a | n/a |
The University of Jordan Curated by ChEMBL | Assay Description Inhibition of human cathepsin L using fluorogenic substrate cbz-FR-AMC monitored for 90 to 120 mins by spectrophotometry | J Med Chem 62: 9026-9044 (2019) Article DOI: 10.1021/acs.jmedchem.9b00294 BindingDB Entry DOI: 10.7270/Q2H998GC | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Procathepsin L (Homo sapiens (Human)) | BDBM50505568 (CHEMBL4482954) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 1.70 | n/a | n/a | n/a | n/a | n/a | n/a |
The University of Jordan Curated by ChEMBL | Assay Description Inhibition of human cathepsin L using fluorogenic substrate cbz-FR-AMC monitored for 90 to 120 mins by spectrophotometry | J Med Chem 62: 9026-9044 (2019) Article DOI: 10.1021/acs.jmedchem.9b00294 BindingDB Entry DOI: 10.7270/Q2H998GC | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Procathepsin L (Homo sapiens (Human)) | BDBM50505565 (CHEMBL4474668) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 1.70 | n/a | n/a | n/a | n/a | n/a | n/a |
The University of Jordan Curated by ChEMBL | Assay Description Inhibition of human cathepsin L using fluorogenic substrate cbz-FR-AMC monitored for 90 to 120 mins by spectrophotometry | J Med Chem 62: 9026-9044 (2019) Article DOI: 10.1021/acs.jmedchem.9b00294 BindingDB Entry DOI: 10.7270/Q2H998GC | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cruzipain (Trypanosoma cruzi) | BDBM50505567 (CHEMBL4457500) | PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 2.90 | n/a | n/a | n/a | n/a | n/a | n/a |
The University of Jordan Curated by ChEMBL | Assay Description Inhibition of recombinant Trypanosoma cruzi Cruzain expressed in Pichia pastoris using Z-Phe-Arg-AMC substrate incubated for 30 mins by fluorescence ... | J Med Chem 62: 9026-9044 (2019) Article DOI: 10.1021/acs.jmedchem.9b00294 BindingDB Entry DOI: 10.7270/Q2H998GC | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Procathepsin L (Homo sapiens (Human)) | BDBM50505564 (CHEMBL4527867) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 3.10 | n/a | n/a | n/a | n/a | n/a | n/a |
The University of Jordan Curated by ChEMBL | Assay Description Inhibition of human cathepsin L using fluorogenic substrate cbz-FR-AMC monitored for 90 to 120 mins by spectrophotometry | J Med Chem 62: 9026-9044 (2019) Article DOI: 10.1021/acs.jmedchem.9b00294 BindingDB Entry DOI: 10.7270/Q2H998GC | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Procathepsin L (Homo sapiens (Human)) | BDBM50505561 (CHEMBL4475810) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 3.5 | n/a | n/a | n/a | n/a | n/a | n/a |
The University of Jordan Curated by ChEMBL | Assay Description Inhibition of human cathepsin L using fluorogenic substrate cbz-FR-AMC monitored for 90 to 120 mins by spectrophotometry | J Med Chem 62: 9026-9044 (2019) Article DOI: 10.1021/acs.jmedchem.9b00294 BindingDB Entry DOI: 10.7270/Q2H998GC | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Procathepsin L (Homo sapiens (Human)) | BDBM50505563 (CHEMBL4527329) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 3.5 | n/a | n/a | n/a | n/a | n/a | n/a |
The University of Jordan Curated by ChEMBL | Assay Description Inhibition of human cathepsin L using fluorogenic substrate cbz-FR-AMC monitored for 90 to 120 mins by spectrophotometry | J Med Chem 62: 9026-9044 (2019) Article DOI: 10.1021/acs.jmedchem.9b00294 BindingDB Entry DOI: 10.7270/Q2H998GC | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cruzipain (Trypanosoma cruzi) | BDBM50505566 (CHEMBL4582558) | PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 3.70 | n/a | n/a | n/a | n/a | n/a | n/a |
The University of Jordan Curated by ChEMBL | Assay Description Inhibition of recombinant Trypanosoma cruzi Cruzain expressed in Pichia pastoris using Z-Phe-Arg-AMC substrate incubated for 30 mins by fluorescence ... | J Med Chem 62: 9026-9044 (2019) Article DOI: 10.1021/acs.jmedchem.9b00294 BindingDB Entry DOI: 10.7270/Q2H998GC | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Procathepsin L (Homo sapiens (Human)) | BDBM50505554 (CHEMBL4564747) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 4.20 | n/a | n/a | n/a | n/a | n/a | n/a |
The University of Jordan Curated by ChEMBL | Assay Description Inhibition of human cathepsin L using fluorogenic substrate cbz-FR-AMC monitored for 90 to 120 mins by spectrophotometry | J Med Chem 62: 9026-9044 (2019) Article DOI: 10.1021/acs.jmedchem.9b00294 BindingDB Entry DOI: 10.7270/Q2H998GC | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Procathepsin L (Homo sapiens (Human)) | BDBM50033762 (Gallinamide A) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase MCE PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 4.70 | n/a | n/a | n/a | n/a | n/a | n/a |
The University of Jordan Curated by ChEMBL | Assay Description Inhibition of human cathepsin L using fluorogenic substrate cbz-FR-AMC monitored for 90 to 120 mins by spectrophotometry | J Med Chem 62: 9026-9044 (2019) Article DOI: 10.1021/acs.jmedchem.9b00294 BindingDB Entry DOI: 10.7270/Q2H998GC | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Procathepsin L (Homo sapiens (Human)) | BDBM50033762 (Gallinamide A) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase MCE PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 5 | n/a | n/a | n/a | n/a | n/a | n/a |
The University of Jordan Curated by ChEMBL | Assay Description Inhibition of human cathepsin L | J Med Chem 62: 9026-9044 (2019) Article DOI: 10.1021/acs.jmedchem.9b00294 BindingDB Entry DOI: 10.7270/Q2H998GC | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Procathepsin L (Homo sapiens (Human)) | BDBM50505567 (CHEMBL4457500) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 6.60 | n/a | n/a | n/a | n/a | n/a | n/a |
The University of Jordan Curated by ChEMBL | Assay Description Inhibition of human cathepsin L using fluorogenic substrate cbz-FR-AMC monitored for 90 to 120 mins by spectrophotometry | J Med Chem 62: 9026-9044 (2019) Article DOI: 10.1021/acs.jmedchem.9b00294 BindingDB Entry DOI: 10.7270/Q2H998GC | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Histone deacetylase 1 (Homo sapiens (Human)) | BDBM50550344 (CHEMBL4798363) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | KEGG PC cid PC sid UniChem | PubMed | n/a | n/a | 21 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Inhibition of recombinant HDAC1 (unknown origin) incubated for 15 mins before substrate addition and measured after 30 to 45 mins by HDAC-Glo substra... | Citation and Details BindingDB Entry DOI: 10.7270/Q2VH5SG7 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Histone deacetylase 3 (Homo sapiens (Human)) | BDBM50550344 (CHEMBL4798363) | PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | KEGG PC cid PC sid UniChem | PubMed | n/a | n/a | 27 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Inhibition of recombinant HDAC3 (unknown origin)incubated for 15 mins before substrate addition and measured after 30 to 45 mins by HDAC-Glo substrat... | Citation and Details BindingDB Entry DOI: 10.7270/Q2VH5SG7 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Histone deacetylase 2 (Homo sapiens (Human)) | BDBM50550344 (CHEMBL4798363) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | KEGG PC cid PC sid UniChem | PubMed | n/a | n/a | 28 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Inhibition of recombinant HDAC2 (unknown origin)incubated for 15 mins before substrate addition and measured after 30 to 45 mins by HDAC-Glo substrat... | Citation and Details BindingDB Entry DOI: 10.7270/Q2VH5SG7 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cruzipain (Trypanosoma cruzi) | BDBM50505558 (CHEMBL4514842) | PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 37 | n/a | n/a | n/a | n/a | n/a | n/a |
The University of Jordan Curated by ChEMBL | Assay Description Inhibition of recombinant Trypanosoma cruzi Cruzain expressed in Pichia pastoris using Z-Phe-Arg-AMC substrate incubated for 30 mins by fluorescence ... | J Med Chem 62: 9026-9044 (2019) Article DOI: 10.1021/acs.jmedchem.9b00294 BindingDB Entry DOI: 10.7270/Q2H998GC | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Histone deacetylase 3 (Homo sapiens (Human)) | BDBM50322422 (CHEMBL1173445 | Largazole) | PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL KEGG PC cid PC sid UniChem Patents Similars | PubMed | n/a | n/a | 50 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Inhibition of recombinant HDAC3 (unknown origin)incubated for 15 mins before substrate addition and measured after 30 to 45 mins by HDAC-Glo substrat... | Citation and Details BindingDB Entry DOI: 10.7270/Q2VH5SG7 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Histone deacetylase 1 (Homo sapiens (Human)) | BDBM50322422 (CHEMBL1173445 | Largazole) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL KEGG PC cid PC sid UniChem Patents Similars | PubMed | n/a | n/a | 61 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Inhibition of recombinant HDAC1 (unknown origin) incubated for 15 mins before substrate addition and measured after 30 to 45 mins by HDAC-Glo substra... | Citation and Details BindingDB Entry DOI: 10.7270/Q2VH5SG7 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Histone deacetylase 2 (Homo sapiens (Human)) | BDBM50322422 (CHEMBL1173445 | Largazole) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL KEGG PC cid PC sid UniChem Patents Similars | PubMed | n/a | n/a | 64 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Inhibition of recombinant HDAC2 (unknown origin)incubated for 15 mins before substrate addition and measured after 30 to 45 mins by HDAC-Glo substrat... | Citation and Details BindingDB Entry DOI: 10.7270/Q2VH5SG7 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Procathepsin L (Homo sapiens (Human)) | BDBM50505558 (CHEMBL4514842) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 77 | n/a | n/a | n/a | n/a | n/a | n/a |
The University of Jordan Curated by ChEMBL | Assay Description Inhibition of human cathepsin L using fluorogenic substrate cbz-FR-AMC monitored for 90 to 120 mins by spectrophotometry | J Med Chem 62: 9026-9044 (2019) Article DOI: 10.1021/acs.jmedchem.9b00294 BindingDB Entry DOI: 10.7270/Q2H998GC | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cruzipain (Trypanosoma cruzi) | BDBM50505556 (CHEMBL4468530) | PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 81 | n/a | n/a | n/a | n/a | n/a | n/a |
The University of Jordan Curated by ChEMBL | Assay Description Inhibition of recombinant Trypanosoma cruzi Cruzain expressed in Pichia pastoris using Z-Phe-Arg-AMC substrate incubated for 30 mins by fluorescence ... | J Med Chem 62: 9026-9044 (2019) Article DOI: 10.1021/acs.jmedchem.9b00294 BindingDB Entry DOI: 10.7270/Q2H998GC | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Procathepsin L (Homo sapiens (Human)) | BDBM50505556 (CHEMBL4468530) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 376 | n/a | n/a | n/a | n/a | n/a | n/a |
The University of Jordan Curated by ChEMBL | Assay Description Inhibition of human cathepsin L using fluorogenic substrate cbz-FR-AMC monitored for 90 to 120 mins by spectrophotometry | J Med Chem 62: 9026-9044 (2019) Article DOI: 10.1021/acs.jmedchem.9b00294 BindingDB Entry DOI: 10.7270/Q2H998GC | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Histone deacetylase 6 (Homo sapiens (Human)) | BDBM50322422 (CHEMBL1173445 | Largazole) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL KEGG PC cid PC sid UniChem Patents Similars | PubMed | n/a | n/a | 1.40E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Inhibition of recombinant HDAC6 (unknown origin)incubated for 15 mins before substrate addition and measured after 30 to 45 mins by HDAC-Glo substrat... | Citation and Details BindingDB Entry DOI: 10.7270/Q2VH5SG7 | |||||||||||
More data for this Ligand-Target Pair |
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