Compile Data Set for Download or QSAR

Found 1183 hits with Last Name = 'amrein' and Initial = 'k'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Cytochrome P450 11B2, mitochondrial (Homo sapiens (Human))	BDBM50541792 (CHEMBL4635011) Show SMILES Cn1cc(cn1)C(=O)N1CC(C1)Oc1cncc(c1)N1C(=O)c2ccc(Cl)cc2C1(C)C Show InChI InChI=1S/C23H22ClN5O3/c1-23(2)20-6-15(24)4-5-19(20)22(31)29(23)16-7-17(10-25-9-16)32-18-12-28(13-18)21(30)14-8-26-27(3)11-14/h4-11,18H,12-13H2,1-3H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid PDB UniChem	PDB Article PubMed	n/a	n/a	0.5	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of human CYP11B2 expressed in human renal leiomyoblastoma cells harboring FDXR/FDX using 1-deoxycorticosterone as substrate by HTRF assay				J Med Chem 63: 6876-6897 (2020) Article DOI: 10.1021/acs.jmedchem.0c00233 BindingDB Entry DOI: 10.7270/Q2H998RZ
					More data for this Ligand-Target Pair				3D Structure (crystal)
Cytochrome P450 11B2, mitochondrial (Homo sapiens (Human))	BDBM50541786 (CHEMBL4647543) Show SMILES CCS(=O)(=O)N1CC(C1)Oc1cncc(c1)N1C(=O)c2ccc(Cl)cc2C1(C)C Show InChI InChI=1S/C20H22ClN3O4S/c1-4-29(26,27)23-11-16(12-23)28-15-8-14(9-22-10-15)24-19(25)17-6-5-13(21)7-18(17)20(24,2)3/h5-10,16H,4,11-12H2,1-3H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	<1	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of CYP11B2 in HEK293 cell assessed as reduction in 18-hyroxycorticosterone by LC/MS-MS method				J Med Chem 63: 6876-6897 (2020) Article DOI: 10.1021/acs.jmedchem.0c00233 BindingDB Entry DOI: 10.7270/Q2H998RZ
					More data for this Ligand-Target Pair
Cytochrome P450 11B2, mitochondrial (Homo sapiens (Human))	BDBM50541786 (CHEMBL4647543) Show SMILES CCS(=O)(=O)N1CC(C1)Oc1cncc(c1)N1C(=O)c2ccc(Cl)cc2C1(C)C Show InChI InChI=1S/C20H22ClN3O4S/c1-4-29(26,27)23-11-16(12-23)28-15-8-14(9-22-10-15)24-19(25)17-6-5-13(21)7-18(17)20(24,2)3/h5-10,16H,4,11-12H2,1-3H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	<1	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of CYP11B2 in HEK293 cell assessed as reduction in aldosterone by LC/MS-MS method				J Med Chem 63: 6876-6897 (2020) Article DOI: 10.1021/acs.jmedchem.0c00233 BindingDB Entry DOI: 10.7270/Q2H998RZ
					More data for this Ligand-Target Pair
Cytochrome P450 11B2, mitochondrial (Homo sapiens (Human))	BDBM50541785 (CHEMBL4635517) Show SMILES CC1(C)N(C(=O)c2ccc(Cl)cc12)c1cncc(c1)N1CCN(CC1)S(C)(=O)=O Show InChI InChI=1S/C20H23ClN4O3S/c1-20(2)18-10-14(21)4-5-17(18)19(26)25(20)16-11-15(12-22-13-16)23-6-8-24(9-7-23)29(3,27)28/h4-5,10-13H,6-9H2,1-3H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	2	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of human CYP11B2 expressed in human renal leiomyoblastoma cells harboring FDXR/FDX using 1-deoxycorticosterone as substrate by HTRF assay				J Med Chem 63: 6876-6897 (2020) Article DOI: 10.1021/acs.jmedchem.0c00233 BindingDB Entry DOI: 10.7270/Q2H998RZ
					More data for this Ligand-Target Pair
Cytochrome P450 11B2, mitochondrial (Homo sapiens (Human))	BDBM279728 (5-Chloro-3,3-dimethyl-2-[5-[2-(1-methylpyrazole-4-...) Show SMILES Cn1cc(cn1)C(=O)N1CC2(C1)CN(C2)c1cncc(c1)N1C(=O)c2ccc(Cl)cc2C1(C)C Show InChI InChI=1S/C25H25ClN6O2/c1-24(2)21-6-17(26)4-5-20(21)23(34)32(24)19-7-18(9-27-10-19)30-12-25(13-30)14-31(15-25)22(33)16-8-28-29(3)11-16/h4-11H,12-15H2,1-3H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	2	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of human CYP11B2 expressed in human renal leiomyoblastoma cells harboring FDXR/FDX using 1-deoxycorticosterone as substrate by HTRF assay				J Med Chem 63: 6876-6897 (2020) Article DOI: 10.1021/acs.jmedchem.0c00233 BindingDB Entry DOI: 10.7270/Q2H998RZ
					More data for this Ligand-Target Pair
Cytochrome P450 11B2, mitochondrial (Homo sapiens (Human))	BDBM50444549 (CHEMBL3099695) Show SMILES Fc1cc(ccc1[C@H]1CCc2cncn12)C#N |r| Show InChI InChI=1S/C13H10FN3/c14-12-5-9(6-15)1-3-11(12)13-4-2-10-7-16-8-17(10)13/h1,3,5,7-8,13H,2,4H2/t13-/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid PDB UniChem Similars	PDB Article PubMed	n/a	n/a	3	n/a	n/a	n/a	n/a	n/a	n/a
Roche Pharma Research and Early Development (pRED) Curated by ChEMBL					Assay Description Inhibition of human CYP11B2 expressed in renal leiomyoblastoma cells				J Med Chem 58: 8054-65 (2015) Article DOI: 10.1021/acs.jmedchem.5b00851 BindingDB Entry DOI: 10.7270/Q2K0763C
					More data for this Ligand-Target Pair				3D Structure (crystal)
Cytochrome P450 11B2, mitochondrial (Homo sapiens (Human))	BDBM50541783 (CHEMBL4642895) Show SMILES CCS(=O)(=O)N1CCC(CC1)c1cncc(c1)N1C(=O)c2ccc(Cl)cc2C1(C)C Show InChI InChI=1S/C22H26ClN3O3S/c1-4-30(28,29)25-9-7-15(8-10-25)16-11-18(14-24-13-16)26-21(27)19-6-5-17(23)12-20(19)22(26,2)3/h5-6,11-15H,4,7-10H2,1-3H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	3	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of human CYP11B2 expressed in human renal leiomyoblastoma cells harboring FDXR/FDX using 1-deoxycorticosterone as substrate by HTRF assay				J Med Chem 63: 6876-6897 (2020) Article DOI: 10.1021/acs.jmedchem.0c00233 BindingDB Entry DOI: 10.7270/Q2H998RZ
					More data for this Ligand-Target Pair
Cytochrome P450 11B2, mitochondrial (Homo sapiens (Human))	BDBM50541789 (CHEMBL4646980) Show SMILES CC(=O)N1CCC(CC1)Oc1cncc(c1)N1C(=O)c2ccc(Cl)cc2C1(C)C Show InChI InChI=1S/C22H24ClN3O3/c1-14(27)25-8-6-17(7-9-25)29-18-11-16(12-24-13-18)26-21(28)19-5-4-15(23)10-20(19)22(26,2)3/h4-5,10-13,17H,6-9H2,1-3H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	4	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of human CYP11B2 expressed in human renal leiomyoblastoma cells harboring FDXR/FDX using 1-deoxycorticosterone as substrate by HTRF assay				J Med Chem 63: 6876-6897 (2020) Article DOI: 10.1021/acs.jmedchem.0c00233 BindingDB Entry DOI: 10.7270/Q2H998RZ
					More data for this Ligand-Target Pair
Cytochrome P450 11B2, mitochondrial (Homo sapiens (Human))	BDBM50541791 (CHEMBL4642138) Show SMILES Cc1ccncc1C(=O)N1CC(C1)Oc1cncc(c1)N1C(=O)c2ccc(Cl)cc2C1(C)C Show InChI InChI=1S/C25H23ClN4O3/c1-15-6-7-27-12-21(15)23(31)29-13-19(14-29)33-18-9-17(10-28-11-18)30-24(32)20-5-4-16(26)8-22(20)25(30,2)3/h4-12,19H,13-14H2,1-3H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	4	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of human CYP11B2 expressed in human renal leiomyoblastoma cells harboring FDXR/FDX using 1-deoxycorticosterone as substrate by HTRF assay				J Med Chem 63: 6876-6897 (2020) Article DOI: 10.1021/acs.jmedchem.0c00233 BindingDB Entry DOI: 10.7270/Q2H998RZ
					More data for this Ligand-Target Pair
Cytochrome P450 11B2, mitochondrial (Homo sapiens (Human))	BDBM50541764 (CHEMBL4645158) Show SMILES C[C@@H]1N(C(=O)c2ccc(Cl)cc12)c1cncc2[C@@H](CCCc12)NC(C)=O |r| Show InChI InChI=1S/C20H20ClN3O2/c1-11-16-8-13(21)6-7-15(16)20(26)24(11)19-10-22-9-17-14(19)4-3-5-18(17)23-12(2)25/h6-11,18H,3-5H2,1-2H3,(H,23,25)/t11-,18+/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	4	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of human CYP11B2 expressed in human renal leiomyoblastoma cells harboring FDXR/FDX using 1-deoxycorticosterone as substrate by HTRF assay				J Med Chem 63: 6876-6897 (2020) Article DOI: 10.1021/acs.jmedchem.0c00233 BindingDB Entry DOI: 10.7270/Q2H998RZ
					More data for this Ligand-Target Pair
Cytochrome P450 11B2, mitochondrial (Homo sapiens (Human))	BDBM50541786 (CHEMBL4647543) Show SMILES CCS(=O)(=O)N1CC(C1)Oc1cncc(c1)N1C(=O)c2ccc(Cl)cc2C1(C)C Show InChI InChI=1S/C20H22ClN3O4S/c1-4-29(26,27)23-11-16(12-23)28-15-8-14(9-22-10-15)24-19(25)17-6-5-13(21)7-18(17)20(24,2)3/h5-10,16H,4,11-12H2,1-3H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	4	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of human CYP11B2 expressed in human renal leiomyoblastoma cells harboring FDXR/FDX using 1-deoxycorticosterone as substrate by HTRF assay				J Med Chem 63: 6876-6897 (2020) Article DOI: 10.1021/acs.jmedchem.0c00233 BindingDB Entry DOI: 10.7270/Q2H998RZ
					More data for this Ligand-Target Pair
Cytochrome P450 11B2, mitochondrial (Homo sapiens (Human))	BDBM50541790 (CHEMBL4632945) Show SMILES CC1(C)N(C(=O)c2ccc(Cl)cc12)c1cncc(OC2CN(C2)C(=O)c2ncccc2Cl)c1 Show InChI InChI=1S/C24H20Cl2N4O3/c1-24(2)19-8-14(25)5-6-18(19)22(31)30(24)15-9-16(11-27-10-15)33-17-12-29(13-17)23(32)21-20(26)4-3-7-28-21/h3-11,17H,12-13H2,1-2H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	5	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of human CYP11B2 expressed in human renal leiomyoblastoma cells harboring FDXR/FDX using 1-deoxycorticosterone as substrate by HTRF assay				J Med Chem 63: 6876-6897 (2020) Article DOI: 10.1021/acs.jmedchem.0c00233 BindingDB Entry DOI: 10.7270/Q2H998RZ
					More data for this Ligand-Target Pair
Cytochrome P450 11B2, mitochondrial (Homo sapiens (Human))	BDBM50541782 (CHEMBL4644311) Show SMILES CC(=O)N1CCC(CC1)c1cncc(c1)N1C(=O)c2ccc(Cl)cc2C1(C)C Show InChI InChI=1S/C22H24ClN3O2/c1-14(27)25-8-6-15(7-9-25)16-10-18(13-24-12-16)26-21(28)19-5-4-17(23)11-20(19)22(26,2)3/h4-5,10-13,15H,6-9H2,1-3H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	5	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of human CYP11B2 expressed in human renal leiomyoblastoma cells harboring FDXR/FDX using 1-deoxycorticosterone as substrate by HTRF assay				J Med Chem 63: 6876-6897 (2020) Article DOI: 10.1021/acs.jmedchem.0c00233 BindingDB Entry DOI: 10.7270/Q2H998RZ
					More data for this Ligand-Target Pair
Cytochrome P450 11B2, mitochondrial (Homo sapiens (Human))	BDBM8611 (4-{5H,6H,7H,8H-imidazo[1,5-a]pyridin-5-yl}benzonit...) Show SMILES N#Cc1ccc(cc1)C1CCCc2cncn12 Show InChI InChI=1S/C14H13N3/c15-8-11-4-6-12(7-5-11)14-3-1-2-13-9-16-10-17(13)14/h4-7,9-10,14H,1-3H2	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid PDB UniChem Patents Similars	PDB Article PubMed	n/a	n/a	6	n/a	n/a	n/a	n/a	n/a	n/a
Roche Pharma Research and Early Development (pRED) Curated by ChEMBL					Assay Description Inhibition of human CYP11B2 expressed in renal leiomyoblastoma cells				J Med Chem 58: 8054-65 (2015) Article DOI: 10.1021/acs.jmedchem.5b00851 BindingDB Entry DOI: 10.7270/Q2K0763C
					More data for this Ligand-Target Pair				3D Structure (crystal)
Cytochrome P450 11B2, mitochondrial (Homo sapiens (Human))	BDBM50541768 (CHEMBL4647877) Show SMILES CCC(=O)N[C@@H]1CCCc2c1cncc2N1[C@@H](C)c2cc(Cl)ccc2C1=O |r| Show InChI InChI=1S/C21H22ClN3O2/c1-3-20(26)24-18-6-4-5-14-17(18)10-23-11-19(14)25-12(2)16-9-13(22)7-8-15(16)21(25)27/h7-12,18H,3-6H2,1-2H3,(H,24,26)/t12-,18+/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	6	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of human CYP11B2 expressed in human renal leiomyoblastoma cells harboring FDXR/FDX using 1-deoxycorticosterone as substrate by HTRF assay				J Med Chem 63: 6876-6897 (2020) Article DOI: 10.1021/acs.jmedchem.0c00233 BindingDB Entry DOI: 10.7270/Q2H998RZ
					More data for this Ligand-Target Pair
Cytochrome P450 11B2, mitochondrial (Homo sapiens (Human))	BDBM50541765 (CHEMBL4639314) Show SMILES CC[C@H]1N(C(=O)c2ccc(Cl)cc12)c1cncc2[C@@H](CCCc12)NC(C)=O |r| Show InChI InChI=1S/C21H22ClN3O2/c1-3-19-16-9-13(22)7-8-15(16)21(27)25(19)20-11-23-10-17-14(20)5-4-6-18(17)24-12(2)26/h7-11,18-19H,3-6H2,1-2H3,(H,24,26)/t18-,19-/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	7	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of human CYP11B2 expressed in human renal leiomyoblastoma cells harboring FDXR/FDX using 1-deoxycorticosterone as substrate by HTRF assay				J Med Chem 63: 6876-6897 (2020) Article DOI: 10.1021/acs.jmedchem.0c00233 BindingDB Entry DOI: 10.7270/Q2H998RZ
					More data for this Ligand-Target Pair
Cytochrome P450 11B2, mitochondrial (Homo sapiens (Human))	BDBM50541788 (CHEMBL4638889) Show SMILES CC(=O)N1CC[C@@H](C1)Oc1cncc(c1)N1C(=O)c2ccc(Cl)cc2C1(C)C |r| Show InChI InChI=1S/C21H22ClN3O3/c1-13(26)24-7-6-16(12-24)28-17-9-15(10-23-11-17)25-20(27)18-5-4-14(22)8-19(18)21(25,2)3/h4-5,8-11,16H,6-7,12H2,1-3H3/t16-/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	7	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of human CYP11B2 expressed in human renal leiomyoblastoma cells harboring FDXR/FDX using 1-deoxycorticosterone as substrate by HTRF assay				J Med Chem 63: 6876-6897 (2020) Article DOI: 10.1021/acs.jmedchem.0c00233 BindingDB Entry DOI: 10.7270/Q2H998RZ
					More data for this Ligand-Target Pair
Cytochrome P450 11B2, mitochondrial (Homo sapiens (Human))	BDBM50541779 (CHEMBL4632486) Show SMILES C[C@@H](NS(C)(=O)=O)c1cncc(c1)N1C(=O)c2ccc(Cl)cc2C1(C)C |r| Show InChI InChI=1S/C18H20ClN3O3S/c1-11(21-26(4,24)25)12-7-14(10-20-9-12)22-17(23)15-6-5-13(19)8-16(15)18(22,2)3/h5-11,21H,1-4H3/t11-/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid PDB UniChem	PDB Article PubMed	n/a	n/a	8	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of human CYP11B2 expressed in human renal leiomyoblastoma cells harboring FDXR/FDX using 1-deoxycorticosterone as substrate by HTRF assay				J Med Chem 63: 6876-6897 (2020) Article DOI: 10.1021/acs.jmedchem.0c00233 BindingDB Entry DOI: 10.7270/Q2H998RZ
					More data for this Ligand-Target Pair				3D Structure (crystal)
Cytochrome P450 11B2, mitochondrial (Homo sapiens (Human))	BDBM50541781 (CHEMBL4643528) Show SMILES Cc1cccnc1C(=O)NCc1cncc(c1)N1C(=O)c2ccc(Cl)cc2C1(C)C Show InChI InChI=1S/C23H21ClN4O2/c1-14-5-4-8-26-20(14)21(29)27-12-15-9-17(13-25-11-15)28-22(30)18-7-6-16(24)10-19(18)23(28,2)3/h4-11,13H,12H2,1-3H3,(H,27,29)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	9	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of human CYP11B2 expressed in human renal leiomyoblastoma cells harboring FDXR/FDX using 1-deoxycorticosterone as substrate by HTRF assay				J Med Chem 63: 6876-6897 (2020) Article DOI: 10.1021/acs.jmedchem.0c00233 BindingDB Entry DOI: 10.7270/Q2H998RZ
					More data for this Ligand-Target Pair
Cytochrome P450 11B2, mitochondrial (Homo sapiens (Human))	BDBM50125049 (CHEMBL3623830) Show SMILES CCC(=O)N[C@@H]1CCCc2c1cncc2-c1ccc(cc1)C#N |r| Show InChI InChI=1S/C19H19N3O/c1-2-19(23)22-18-5-3-4-15-16(11-21-12-17(15)18)14-8-6-13(10-20)7-9-14/h6-9,11-12,18H,2-5H2,1H3,(H,22,23)/t18-/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	9	n/a	n/a	n/a	n/a	n/a	n/a
Roche Pharma Research and Early Development (pRED) Curated by ChEMBL					Assay Description Inhibition of human CYP11B2 expressed in human renal leiomyoblastoma cells using 11-deoxycorticosterone as substrate assessed as formation of aldoste...				J Med Chem 58: 8054-65 (2015) Article DOI: 10.1021/acs.jmedchem.5b00851 BindingDB Entry DOI: 10.7270/Q2K0763C
					More data for this Ligand-Target Pair
Cytochrome P450 11B2, mitochondrial (Homo sapiens (Human))	BDBM50541784 (CHEMBL4634550) Show SMILES CC(=O)N1CCN(CC1)c1cncc(c1)N1C(=O)c2ccc(Cl)cc2C1(C)C Show InChI InChI=1S/C21H23ClN4O2/c1-14(27)24-6-8-25(9-7-24)16-11-17(13-23-12-16)26-20(28)18-5-4-15(22)10-19(18)21(26,2)3/h4-5,10-13H,6-9H2,1-3H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	9	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of human CYP11B2 expressed in human renal leiomyoblastoma cells harboring FDXR/FDX using 1-deoxycorticosterone as substrate by HTRF assay				J Med Chem 63: 6876-6897 (2020) Article DOI: 10.1021/acs.jmedchem.0c00233 BindingDB Entry DOI: 10.7270/Q2H998RZ
					More data for this Ligand-Target Pair
Cytochrome P450 11B2, mitochondrial (Homo sapiens (Human))	BDBM50541787 (CHEMBL4634463) Show SMILES CC(=O)N1CC[C@H](C1)Oc1cncc(c1)N1C(=O)c2ccc(Cl)cc2C1(C)C |r| Show InChI InChI=1S/C21H22ClN3O3/c1-13(26)24-7-6-16(12-24)28-17-9-15(10-23-11-17)25-20(27)18-5-4-14(22)8-19(18)21(25,2)3/h4-5,8-11,16H,6-7,12H2,1-3H3/t16-/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	11	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of human CYP11B2 expressed in human renal leiomyoblastoma cells harboring FDXR/FDX using 1-deoxycorticosterone as substrate by HTRF assay				J Med Chem 63: 6876-6897 (2020) Article DOI: 10.1021/acs.jmedchem.0c00233 BindingDB Entry DOI: 10.7270/Q2H998RZ
					More data for this Ligand-Target Pair
Cytochrome P450 11B2, mitochondrial (Homo sapiens (Human))	BDBM50541770 (CHEMBL4640951) Show SMILES CC[C@@H]1N(C(=O)c2ccc(Cl)cc12)c1cncc2[C@@H](CCCc12)NC(=O)CC |r| Show InChI InChI=1S/C22H24ClN3O2/c1-3-19-16-10-13(23)8-9-15(16)22(28)26(19)20-12-24-11-17-14(20)6-5-7-18(17)25-21(27)4-2/h8-12,18-19H,3-7H2,1-2H3,(H,25,27)/t18-,19+/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	12	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of human CYP11B2 expressed in human renal leiomyoblastoma cells harboring FDXR/FDX using 1-deoxycorticosterone as substrate by HTRF assay				J Med Chem 63: 6876-6897 (2020) Article DOI: 10.1021/acs.jmedchem.0c00233 BindingDB Entry DOI: 10.7270/Q2H998RZ
					More data for this Ligand-Target Pair
Cytochrome P450 11B2, mitochondrial (Homo sapiens (Human))	BDBM191903 (US9187429, 36 | US9187429, 37 | US9187429, 38) Show SMILES CCC(=O)NC1CCCc2c1cncc2-c1ccc(Cl)c(F)c1 Show InChI InChI=1S/C18H18ClFN2O/c1-2-18(23)22-17-5-3-4-12-13(9-21-10-14(12)17)11-6-7-15(19)16(20)8-11/h6-10,17H,2-5H2,1H3,(H,22,23)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid PDB UniChem Similars	PDB Article PubMed	n/a	n/a	14	n/a	n/a	n/a	n/a	n/a	n/a
Roche Pharma Research and Early Development (pRED) Curated by ChEMBL					Assay Description Inhibition of human CYP11B2 expressed in human renal leiomyoblastoma cells using 11-deoxycorticosterone as substrate assessed as formation of aldoste...				J Med Chem 58: 8054-65 (2015) Article DOI: 10.1021/acs.jmedchem.5b00851 BindingDB Entry DOI: 10.7270/Q2K0763C
					More data for this Ligand-Target Pair				3D Structure (crystal)
Cytochrome P450 11B2, mitochondrial (Homo sapiens (Human))	BDBM279736 (US10035804, Example 7) Show SMILES Cc1ccncc1C(=O)N1CC2(C1)CN(C2)c1cncc(c1)N1C(=O)c2ccc(Cl)cc2C1(C)C Show InChI InChI=1S/C27H26ClN5O2/c1-17-6-7-29-12-22(17)24(34)32-15-27(16-32)13-31(14-27)19-9-20(11-30-10-19)33-25(35)21-5-4-18(28)8-23(21)26(33,2)3/h4-12H,13-16H2,1-3H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	14	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of human CYP11B2 expressed in human renal leiomyoblastoma cells harboring FDXR/FDX using 1-deoxycorticosterone as substrate by HTRF assay				J Med Chem 63: 6876-6897 (2020) Article DOI: 10.1021/acs.jmedchem.0c00233 BindingDB Entry DOI: 10.7270/Q2H998RZ
					More data for this Ligand-Target Pair
Cytochrome P450 11B2, mitochondrial (Homo sapiens (Human))	BDBM50541794 (CHEMBL4640361) Show SMILES CCS(=O)(=O)N1CC2(CN(C2)c2cncc(c2)N2C(=O)c3ccc(Cl)cc3C2(C)C)C1 Show InChI InChI=1S/C22H25ClN4O3S/c1-4-31(29,30)26-13-22(14-26)11-25(12-22)16-8-17(10-24-9-16)27-20(28)18-6-5-15(23)7-19(18)21(27,2)3/h5-10H,4,11-14H2,1-3H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	16	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of human CYP11B2 expressed in human renal leiomyoblastoma cells harboring FDXR/FDX using 1-deoxycorticosterone as substrate by HTRF assay				J Med Chem 63: 6876-6897 (2020) Article DOI: 10.1021/acs.jmedchem.0c00233 BindingDB Entry DOI: 10.7270/Q2H998RZ
					More data for this Ligand-Target Pair
Cytochrome P450 11B2, mitochondrial (Homo sapiens (Human))	BDBM191882 (US9187429, 8) Show SMILES CC(=O)NC1CCCc2c1cncc2-c1ccc(cc1)C#N Show InChI InChI=1S/C18H17N3O/c1-12(22)21-18-4-2-3-15-16(10-20-11-17(15)18)14-7-5-13(9-19)6-8-14/h5-8,10-11,18H,2-4H2,1H3,(H,21,22)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	21	n/a	n/a	n/a	n/a	n/a	n/a
Roche Pharma Research and Early Development (pRED) Curated by ChEMBL					Assay Description Inhibition of human CYP11B2 expressed in human renal leiomyoblastoma cells using 11-deoxycorticosterone as substrate assessed as formation of aldoste...				J Med Chem 58: 8054-65 (2015) Article DOI: 10.1021/acs.jmedchem.5b00851 BindingDB Entry DOI: 10.7270/Q2K0763C
					More data for this Ligand-Target Pair
Cytochrome P450 11B2, mitochondrial (Homo sapiens (Human))	BDBM50541793 (CHEMBL4638415) Show SMILES CC(=O)N1CC2(C1)CN(C2)c1cncc(c1)N1C(=O)c2ccc(Cl)cc2C1(C)C Show InChI InChI=1S/C22H23ClN4O2/c1-14(28)25-10-22(11-25)12-26(13-22)16-7-17(9-24-8-16)27-20(29)18-5-4-15(23)6-19(18)21(27,2)3/h4-9H,10-13H2,1-3H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	23	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of human CYP11B2 expressed in human renal leiomyoblastoma cells harboring FDXR/FDX using 1-deoxycorticosterone as substrate by HTRF assay				J Med Chem 63: 6876-6897 (2020) Article DOI: 10.1021/acs.jmedchem.0c00233 BindingDB Entry DOI: 10.7270/Q2H998RZ
					More data for this Ligand-Target Pair
Cytochrome P450 11B2, mitochondrial (Homo sapiens (Human))	BDBM191880 (US9187429, 5 | US9187429, 6 | US9187429, 7) Show SMILES CCC(=O)NC1CCCc2c1cncc2-c1ccc(cc1)C#N Show InChI InChI=1S/C19H19N3O/c1-2-19(23)22-18-5-3-4-15-16(11-21-12-17(15)18)14-8-6-13(10-20)7-9-14/h6-9,11-12,18H,2-5H2,1H3,(H,22,23)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	25	n/a	n/a	n/a	n/a	n/a	n/a
Roche Pharma Research and Early Development (pRED) Curated by ChEMBL					Assay Description Inhibition of human CYP11B2 expressed in human renal leiomyoblastoma cells using 11-deoxycorticosterone as substrate assessed as formation of aldoste...				J Med Chem 58: 8054-65 (2015) Article DOI: 10.1021/acs.jmedchem.5b00851 BindingDB Entry DOI: 10.7270/Q2K0763C
					More data for this Ligand-Target Pair
Cytochrome P450 11B2, mitochondrial (Homo sapiens (Human))	BDBM191908 (US9187429, 43) Show SMILES CCC(=O)NC1CCCc2c1cncc2-c1cc(F)c(F)cc1F Show InChI InChI=1S/C18H17F3N2O/c1-2-18(24)23-17-5-3-4-10-12(8-22-9-13(10)17)11-6-15(20)16(21)7-14(11)19/h6-9,17H,2-5H2,1H3,(H,23,24)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	27	n/a	n/a	n/a	n/a	n/a	n/a
Roche Pharma Research and Early Development (pRED) Curated by ChEMBL					Assay Description Inhibition of human CYP11B2 expressed in human renal leiomyoblastoma cells using 11-deoxycorticosterone as substrate assessed as formation of aldoste...				J Med Chem 58: 8054-65 (2015) Article DOI: 10.1021/acs.jmedchem.5b00851 BindingDB Entry DOI: 10.7270/Q2K0763C
					More data for this Ligand-Target Pair
Cytochrome P450 11B2, mitochondrial (Homo sapiens (Human))	BDBM50541760 (CHEMBL4642777) Show SMILES CCC(=O)N[C@@H]1CCCc2c1cncc2N1Cc2cc(Cl)ccc2C1=O |r| Show InChI InChI=1S/C20H20ClN3O2/c1-2-19(25)23-17-5-3-4-15-16(17)9-22-10-18(15)24-11-12-8-13(21)6-7-14(12)20(24)26/h6-10,17H,2-5,11H2,1H3,(H,23,25)/t17-/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	28	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of human CYP11B2 expressed in human renal leiomyoblastoma cells harboring FDXR/FDX using 1-deoxycorticosterone as substrate by HTRF assay				J Med Chem 63: 6876-6897 (2020) Article DOI: 10.1021/acs.jmedchem.0c00233 BindingDB Entry DOI: 10.7270/Q2H998RZ
					More data for this Ligand-Target Pair
Cytochrome P450 11B2, mitochondrial (Homo sapiens (Human))	BDBM191899 (US9187429, 30 | US9187429, 31 | US9187429, 32) Show SMILES CCC(=O)NC1CCCc2c1cncc2-c1ccc(Cl)cc1F Show InChI InChI=1S/C18H18ClFN2O/c1-2-18(23)22-17-5-3-4-12-14(9-21-10-15(12)17)13-7-6-11(19)8-16(13)20/h6-10,17H,2-5H2,1H3,(H,22,23)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	28	n/a	n/a	n/a	n/a	n/a	n/a
Roche Pharma Research and Early Development (pRED) Curated by ChEMBL					Assay Description Inhibition of human CYP11B2 expressed in human renal leiomyoblastoma cells using 11-deoxycorticosterone as substrate assessed as formation of aldoste...				J Med Chem 58: 8054-65 (2015) Article DOI: 10.1021/acs.jmedchem.5b00851 BindingDB Entry DOI: 10.7270/Q2K0763C
					More data for this Ligand-Target Pair
Cytochrome P450 11B2, mitochondrial (Homo sapiens (Human))	BDBM50541778 (CHEMBL4645918) Show SMILES CC1(C)N(C(=O)c2ccc(Cl)cc12)c1cncc(CNS(C)(=O)=O)c1 Show InChI InChI=1S/C17H18ClN3O3S/c1-17(2)15-7-12(18)4-5-14(15)16(22)21(17)13-6-11(8-19-10-13)9-20-25(3,23)24/h4-8,10,20H,9H2,1-3H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	33	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of human CYP11B2 expressed in human renal leiomyoblastoma cells harboring FDXR/FDX using 1-deoxycorticosterone as substrate by HTRF assay				J Med Chem 63: 6876-6897 (2020) Article DOI: 10.1021/acs.jmedchem.0c00233 BindingDB Entry DOI: 10.7270/Q2H998RZ
					More data for this Ligand-Target Pair
Cytochrome P450 11B2, mitochondrial (Homo sapiens (Human))	BDBM50541762 (CHEMBL4645224) Show SMILES CCS(=O)(=O)N[C@@H]1CCCc2c1cncc2N1Cc2cc(Cl)ccc2C1=O |r| Show InChI InChI=1S/C19H20ClN3O3S/c1-2-27(25,26)22-17-5-3-4-15-16(17)9-21-10-18(15)23-11-12-8-13(20)6-7-14(12)19(23)24/h6-10,17,22H,2-5,11H2,1H3/t17-/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	40	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of human CYP11B2 expressed in human renal leiomyoblastoma cells harboring FDXR/FDX using 1-deoxycorticosterone as substrate by HTRF assay				J Med Chem 63: 6876-6897 (2020) Article DOI: 10.1021/acs.jmedchem.0c00233 BindingDB Entry DOI: 10.7270/Q2H998RZ
					More data for this Ligand-Target Pair
Cytochrome P450 11B2, mitochondrial (Homo sapiens (Human))	BDBM50125051 (CHEMBL3623821) Show SMILES N#Cc1ccc(cc1)-c1cccnc1 Show InChI InChI=1S/C12H8N2/c13-8-10-3-5-11(6-4-10)12-2-1-7-14-9-12/h1-7,9H	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	40	n/a	n/a	n/a	n/a	n/a	n/a
Roche Pharma Research and Early Development (pRED) Curated by ChEMBL					Assay Description Inhibition of human CYP11B2 expressed in human renal leiomyoblastoma cells using 11-deoxycorticosterone as substrate assessed as formation of aldoste...				J Med Chem 58: 8054-65 (2015) Article DOI: 10.1021/acs.jmedchem.5b00851 BindingDB Entry DOI: 10.7270/Q2K0763C
					More data for this Ligand-Target Pair
Cytochrome P450 11B2, mitochondrial (Homo sapiens (Human))	BDBM191876 (US9187429, 1) Show SMILES NC1CCCc2c1cncc2-c1ccc(cc1)C#N Show InChI InChI=1S/C16H15N3/c17-8-11-4-6-12(7-5-11)14-9-19-10-15-13(14)2-1-3-16(15)18/h4-7,9-10,16H,1-3,18H2	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	42	n/a	n/a	n/a	n/a	n/a	n/a
Roche Pharma Research and Early Development (pRED) Curated by ChEMBL					Assay Description Inhibition of human CYP11B2 expressed in human renal leiomyoblastoma cells using 11-deoxycorticosterone as substrate assessed as formation of aldoste...				J Med Chem 58: 8054-65 (2015) Article DOI: 10.1021/acs.jmedchem.5b00851 BindingDB Entry DOI: 10.7270/Q2K0763C
					More data for this Ligand-Target Pair
Cytochrome P450 11B2, mitochondrial (Homo sapiens (Human))	BDBM50541759 (CHEMBL4642814) Show SMILES CC(=O)N[C@@H]1CCCc2c1cncc2N1Cc2cc(Cl)ccc2C1=O |r| Show InChI InChI=1S/C19H18ClN3O2/c1-11(24)22-17-4-2-3-15-16(17)8-21-9-18(15)23-10-12-7-13(20)5-6-14(12)19(23)25/h5-9,17H,2-4,10H2,1H3,(H,22,24)/t17-/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	44	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of human CYP11B2 expressed in human renal leiomyoblastoma cells harboring FDXR/FDX using 1-deoxycorticosterone as substrate by HTRF assay				J Med Chem 63: 6876-6897 (2020) Article DOI: 10.1021/acs.jmedchem.0c00233 BindingDB Entry DOI: 10.7270/Q2H998RZ
					More data for this Ligand-Target Pair
Cytochrome P450 11B2, mitochondrial (Homo sapiens (Human))	BDBM191909 (US9187429, 44) Show SMILES CCC(=O)NC1CCCc2c1cncc2-c1ccc(F)c(F)c1 Show InChI InChI=1S/C18H18F2N2O/c1-2-18(23)22-17-5-3-4-12-13(9-21-10-14(12)17)11-6-7-15(19)16(20)8-11/h6-10,17H,2-5H2,1H3,(H,22,23)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	47	n/a	n/a	n/a	n/a	n/a	n/a
Roche Pharma Research and Early Development (pRED) Curated by ChEMBL					Assay Description Inhibition of human CYP11B2 expressed in human renal leiomyoblastoma cells using 11-deoxycorticosterone as substrate assessed as formation of aldoste...				J Med Chem 58: 8054-65 (2015) Article DOI: 10.1021/acs.jmedchem.5b00851 BindingDB Entry DOI: 10.7270/Q2K0763C
					More data for this Ligand-Target Pair
Cytochrome P450 11B2, mitochondrial (Homo sapiens (Human))	BDBM50541773 (CHEMBL4636239) Show SMILES CC(=O)N[C@@H]1CCCc2c1cncc2N1CCc2cc(Cl)ccc2C1=O |r| Show InChI InChI=1S/C20H20ClN3O2/c1-12(25)23-18-4-2-3-16-17(18)10-22-11-19(16)24-8-7-13-9-14(21)5-6-15(13)20(24)26/h5-6,9-11,18H,2-4,7-8H2,1H3,(H,23,25)/t18-/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	54	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of human CYP11B2 expressed in human renal leiomyoblastoma cells harboring FDXR/FDX using 1-deoxycorticosterone as substrate by HTRF assay				J Med Chem 63: 6876-6897 (2020) Article DOI: 10.1021/acs.jmedchem.0c00233 BindingDB Entry DOI: 10.7270/Q2H998RZ
					More data for this Ligand-Target Pair
Cytochrome P450 11B2, mitochondrial (Homo sapiens (Human))	BDBM50541776 (CHEMBL4639262) Show SMILES CC(=O)NCc1cncc(c1)N1C(=O)c2ccc(Cl)cc2C1(C)C Show InChI InChI=1S/C18H18ClN3O2/c1-11(23)21-9-12-6-14(10-20-8-12)22-17(24)15-5-4-13(19)7-16(15)18(22,2)3/h4-8,10H,9H2,1-3H3,(H,21,23)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	59	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of human CYP11B2 expressed in human renal leiomyoblastoma cells harboring FDXR/FDX using 1-deoxycorticosterone as substrate by HTRF assay				J Med Chem 63: 6876-6897 (2020) Article DOI: 10.1021/acs.jmedchem.0c00233 BindingDB Entry DOI: 10.7270/Q2H998RZ
					More data for this Ligand-Target Pair
Cytochrome P450 11B2, mitochondrial (Homo sapiens (Human))	BDBM50541750 (CHEMBL4635349) Show SMILES Clc1ccc2C(=O)N(CCc2c1)c1cccnc1 Show InChI InChI=1S/C14H11ClN2O/c15-11-3-4-13-10(8-11)5-7-17(14(13)18)12-2-1-6-16-9-12/h1-4,6,8-9H,5,7H2	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	61	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of human CYP11B2 expressed in human renal leiomyoblastoma cells harboring FDXR/FDX using 1-deoxycorticosterone as substrate by HTRF assay				J Med Chem 63: 6876-6897 (2020) Article DOI: 10.1021/acs.jmedchem.0c00233 BindingDB Entry DOI: 10.7270/Q2H998RZ
					More data for this Ligand-Target Pair
Cytochrome P450 11B2, mitochondrial (Homo sapiens (Human))	BDBM50541767 (CHEMBL4644978) Show SMILES CCC(=O)N[C@@H]1CCCc2c1cncc2N1[C@H](C)c2cc(Cl)ccc2C1=O |r| Show InChI InChI=1S/C21H22ClN3O2/c1-3-20(26)24-18-6-4-5-14-17(18)10-23-11-19(14)25-12(2)16-9-13(22)7-8-15(16)21(25)27/h7-12,18H,3-6H2,1-2H3,(H,24,26)/t12-,18-/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	66	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of human CYP11B2 expressed in human renal leiomyoblastoma cells harboring FDXR/FDX using 1-deoxycorticosterone as substrate by HTRF assay				J Med Chem 63: 6876-6897 (2020) Article DOI: 10.1021/acs.jmedchem.0c00233 BindingDB Entry DOI: 10.7270/Q2H998RZ
					More data for this Ligand-Target Pair
Cytochrome P450 11B2, mitochondrial (Homo sapiens (Human))	BDBM50541775 (CHEMBL4649630) Show SMILES CS(=O)(=O)N[C@@H]1CCCc2c1cncc2N1CCc2cc(Cl)ccc2C1=O |r| Show InChI InChI=1S/C19H20ClN3O3S/c1-27(25,26)22-17-4-2-3-15-16(17)10-21-11-18(15)23-8-7-12-9-13(20)5-6-14(12)19(23)24/h5-6,9-11,17,22H,2-4,7-8H2,1H3/t17-/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	76	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of human CYP11B2 expressed in human renal leiomyoblastoma cells harboring FDXR/FDX using 1-deoxycorticosterone as substrate by HTRF assay				J Med Chem 63: 6876-6897 (2020) Article DOI: 10.1021/acs.jmedchem.0c00233 BindingDB Entry DOI: 10.7270/Q2H998RZ
					More data for this Ligand-Target Pair
Cytochrome P450 11B1, mitochondrial (Homo sapiens (Human))	BDBM50541764 (CHEMBL4645158) Show SMILES C[C@@H]1N(C(=O)c2ccc(Cl)cc12)c1cncc2[C@@H](CCCc12)NC(C)=O |r| Show InChI InChI=1S/C20H20ClN3O2/c1-11-16-8-13(21)6-7-15(16)20(26)24(11)19-10-22-9-17-14(19)4-3-5-18(17)23-12(2)25/h6-11,18H,3-5H2,1-2H3,(H,23,25)/t11-,18+/m0/s1	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	81	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of human CYP11B1 expressed in human renal leiomyoblastoma cells harboring FDXR/FDX using 1-deoxycortisol as substrate by HTRF assay				J Med Chem 63: 6876-6897 (2020) Article DOI: 10.1021/acs.jmedchem.0c00233 BindingDB Entry DOI: 10.7270/Q2H998RZ
					More data for this Ligand-Target Pair
Cytochrome P450 11B2, mitochondrial (Homo sapiens (Human))	BDBM50541769 (CHEMBL4646307) Show SMILES CC[C@H]1N(C(=O)c2ccc(Cl)cc12)c1cncc2[C@@H](CCCc12)NC(=O)CC |r| Show InChI InChI=1S/C22H24ClN3O2/c1-3-19-16-10-13(23)8-9-15(16)22(28)26(19)20-12-24-11-17-14(20)6-5-7-18(17)25-21(27)4-2/h8-12,18-19H,3-7H2,1-2H3,(H,25,27)/t18-,19-/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	90	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of human CYP11B2 expressed in human renal leiomyoblastoma cells harboring FDXR/FDX using 1-deoxycorticosterone as substrate by HTRF assay				J Med Chem 63: 6876-6897 (2020) Article DOI: 10.1021/acs.jmedchem.0c00233 BindingDB Entry DOI: 10.7270/Q2H998RZ
					More data for this Ligand-Target Pair
Cytochrome P450 11B2, mitochondrial (Homo sapiens (Human))	BDBM50541780 (CHEMBL4638300) Show SMILES CCS(=O)(=O)NCc1cncc(c1)N1C(=O)c2ccc(Cl)cc2C1(C)C Show InChI InChI=1S/C18H20ClN3O3S/c1-4-26(24,25)21-10-12-7-14(11-20-9-12)22-17(23)15-6-5-13(19)8-16(15)18(22,2)3/h5-9,11,21H,4,10H2,1-3H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	92	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of human CYP11B2 expressed in human renal leiomyoblastoma cells harboring FDXR/FDX using 1-deoxycorticosterone as substrate by HTRF assay				J Med Chem 63: 6876-6897 (2020) Article DOI: 10.1021/acs.jmedchem.0c00233 BindingDB Entry DOI: 10.7270/Q2H998RZ
					More data for this Ligand-Target Pair
Cytochrome P450 11B2, mitochondrial (Homo sapiens (Human))	BDBM50541766 (CHEMBL4633711) Show SMILES CC[C@@H]1N(C(=O)c2ccc(Cl)cc12)c1cncc2[C@@H](CCCc12)NC(C)=O |r| Show InChI InChI=1S/C21H22ClN3O2/c1-3-19-16-9-13(22)7-8-15(16)21(27)25(19)20-11-23-10-17-14(20)5-4-6-18(17)24-12(2)26/h7-11,18-19H,3-6H2,1-2H3,(H,24,26)/t18-,19+/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	97	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of human CYP11B2 expressed in human renal leiomyoblastoma cells harboring FDXR/FDX using 1-deoxycorticosterone as substrate by HTRF assay				J Med Chem 63: 6876-6897 (2020) Article DOI: 10.1021/acs.jmedchem.0c00233 BindingDB Entry DOI: 10.7270/Q2H998RZ
					More data for this Ligand-Target Pair
Cytochrome P450 11B2, mitochondrial (Homo sapiens (Human))	BDBM50541771 (CHEMBL4638099) Show SMILES CC(=O)N[C@@H]1CCCc2c1cncc2N1[C@H](C2CC2)c2cc(Cl)ccc2C1=O |r| Show InChI InChI=1S/C22H22ClN3O2/c1-12(27)25-19-4-2-3-15-18(19)10-24-11-20(15)26-21(13-5-6-13)17-9-14(23)7-8-16(17)22(26)28/h7-11,13,19,21H,2-6H2,1H3,(H,25,27)/t19-,21-/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	100	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of human CYP11B2 expressed in human renal leiomyoblastoma cells harboring FDXR/FDX using 1-deoxycorticosterone as substrate by HTRF assay				J Med Chem 63: 6876-6897 (2020) Article DOI: 10.1021/acs.jmedchem.0c00233 BindingDB Entry DOI: 10.7270/Q2H998RZ
					More data for this Ligand-Target Pair
Cytochrome P450 11B2, mitochondrial (Homo sapiens (Human))	BDBM50541749 (CHEMBL4639620) Show SMILES Fc1cc2C(=O)N(CCc2cc1Cl)c1cccnc1 Show InChI InChI=1S/C14H10ClFN2O/c15-12-6-9-3-5-18(10-2-1-4-17-8-10)14(19)11(9)7-13(12)16/h1-2,4,6-8H,3,5H2	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	104	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of human CYP11B2 expressed in human renal leiomyoblastoma cells harboring FDXR/FDX using 1-deoxycorticosterone as substrate by HTRF assay				J Med Chem 63: 6876-6897 (2020) Article DOI: 10.1021/acs.jmedchem.0c00233 BindingDB Entry DOI: 10.7270/Q2H998RZ
					More data for this Ligand-Target Pair
Cytochrome P450 11B2, mitochondrial (Homo sapiens (Human))	BDBM50541743 (CHEMBL4640325) Show SMILES CC1(C)N(C(=O)c2ccc(Cl)cc12)c1cccnc1 Show InChI InChI=1S/C15H13ClN2O/c1-15(2)13-8-10(16)5-6-12(13)14(19)18(15)11-4-3-7-17-9-11/h3-9H,1-2H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	108	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of human CYP11B2 expressed in human renal leiomyoblastoma cells harboring FDXR/FDX using 1-deoxycorticosterone as substrate by HTRF assay				J Med Chem 63: 6876-6897 (2020) Article DOI: 10.1021/acs.jmedchem.0c00233 BindingDB Entry DOI: 10.7270/Q2H998RZ
					More data for this Ligand-Target Pair

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