Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Glutathionylspermidine synthase (Crithidia fasciculata) | BDBM50117542 (2-Amino-4-[1-(hydroxycarbamoylmethyl-carbamoyl)-3-...) | KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL KEGG PC cid PC sid UniChem Similars | PubMed | 2.50E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Antwerp (UIA) Curated by ChEMBL | Assay Description Inhibitory constant against amidase free Glutathionylspermidine Synthetase mutant (C79A) | Bioorg Med Chem Lett 12: 2553-6 (2002) BindingDB Entry DOI: 10.7270/Q2057F8Z | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Glutathionylspermidine synthase (Crithidia fasciculata) | BDBM50118638 (2-[(S)-2-((S)-4-Amino-4-carboxy-butyrylamino)-4-me...) | KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL KEGG PC cid PC sid UniChem Similars | PubMed | 6.40E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Antwerp (UIA) Curated by ChEMBL | Assay Description Inhibitory constant of the compound was tested against glutathionylspermidine synthetase (GspS) in Crithidia fasciculata | Bioorg Med Chem Lett 12: 2703-5 (2002) BindingDB Entry DOI: 10.7270/Q2MS3S34 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Glutathionylspermidine synthase (Crithidia fasciculata) | BDBM50118638 (2-[(S)-2-((S)-4-Amino-4-carboxy-butyrylamino)-4-me...) | KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL KEGG PC cid PC sid UniChem Similars | PubMed | 6.40E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Antwerp (UIA) Curated by ChEMBL | Assay Description Inhibitory constant of the compound was tested against glutathionylspermidine synthetase (GspS) in Crithidia fasciculata | Bioorg Med Chem Lett 12: 2703-5 (2002) BindingDB Entry DOI: 10.7270/Q2MS3S34 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Glutathionylspermidine synthase (Crithidia fasciculata) | BDBM50118640 ((S)-2-Amino-4-[1-((S)-(S)-2-amino-1-carboxy-ethylc...) | KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL KEGG PC cid PC sid UniChem Similars | PubMed | 7.20E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Antwerp (UIA) Curated by ChEMBL | Assay Description In vitro binding affinity for Histamine H3 receptor | Bioorg Med Chem Lett 12: 2703-5 (2002) BindingDB Entry DOI: 10.7270/Q2MS3S34 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Glutathionylspermidine synthase (Crithidia fasciculata) | BDBM50118640 ((S)-2-Amino-4-[1-((S)-(S)-2-amino-1-carboxy-ethylc...) | KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL KEGG PC cid PC sid UniChem Similars | PubMed | 7.20E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Antwerp (UIA) Curated by ChEMBL | Assay Description Inhibitory constant of the compound was tested against glutathionylspermidine synthetase (GspS) in Crithidia fasciculata | Bioorg Med Chem Lett 12: 2703-5 (2002) BindingDB Entry DOI: 10.7270/Q2MS3S34 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Glutathionylspermidine synthase (Crithidia fasciculata) | BDBM50118642 (5-Amino-2-[(S)-2-((S)-4-amino-4-carboxy-butyrylami...) | KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL KEGG PC cid PC sid UniChem Similars | PubMed | 1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Antwerp (UIA) Curated by ChEMBL | Assay Description Inhibitory constant of the compound was tested against glutathionylspermidine synthetase (GspS) in Crithidia fasciculata | Bioorg Med Chem Lett 12: 2703-5 (2002) BindingDB Entry DOI: 10.7270/Q2MS3S34 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Glutathionylspermidine synthase (Crithidia fasciculata) | BDBM50118642 (5-Amino-2-[(S)-2-((S)-4-amino-4-carboxy-butyrylami...) | KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL KEGG PC cid PC sid UniChem Similars | PubMed | 1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Antwerp (UIA) Curated by ChEMBL | Assay Description Inhibitory constant of the compound was tested against glutathionylspermidine synthetase (GspS) in Crithidia fasciculata | Bioorg Med Chem Lett 12: 2703-5 (2002) BindingDB Entry DOI: 10.7270/Q2MS3S34 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Glutathionylspermidine synthase (Crithidia fasciculata) | BDBM50118643 ((S)-2-Amino-4-[1-((S)-(S)-3-amino-1-carboxy-propyl...) | KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL KEGG PC cid PC sid UniChem Similars | PubMed | 1.04E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Antwerp (UIA) Curated by ChEMBL | Assay Description Inhibitory constant of the compound was tested against glutathionylspermidine synthetase (GspS) in Crithidia fasciculata | Bioorg Med Chem Lett 12: 2703-5 (2002) BindingDB Entry DOI: 10.7270/Q2MS3S34 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Glutathionylspermidine synthase (Crithidia fasciculata) | BDBM50118643 ((S)-2-Amino-4-[1-((S)-(S)-3-amino-1-carboxy-propyl...) | KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL KEGG PC cid PC sid UniChem Similars | PubMed | 1.04E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Antwerp (UIA) Curated by ChEMBL | Assay Description Inhibitory constant of the compound was tested against glutathionylspermidine synthetase (GspS) in Crithidia fasciculata | Bioorg Med Chem Lett 12: 2703-5 (2002) BindingDB Entry DOI: 10.7270/Q2MS3S34 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Glutathionylspermidine synthase (Crithidia fasciculata) | BDBM50118644 ((S)-2-Amino-4-[1-((S)-(S)-1-carboxy-2-hydroxy-ethy...) | KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL KEGG PC cid PC sid UniChem Similars | PubMed | 1.40E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Antwerp (UIA) Curated by ChEMBL | Assay Description Inhibitory constant of the compound was tested against glutathionylspermidine synthetase (GspS) in Crithidia fasciculata | Bioorg Med Chem Lett 12: 2703-5 (2002) BindingDB Entry DOI: 10.7270/Q2MS3S34 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Glutathionylspermidine synthase (Crithidia fasciculata) | BDBM50118644 ((S)-2-Amino-4-[1-((S)-(S)-1-carboxy-2-hydroxy-ethy...) | KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL KEGG PC cid PC sid UniChem Similars | PubMed | 1.40E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Antwerp (UIA) Curated by ChEMBL | Assay Description Inhibitory constant of the compound was tested against glutathionylspermidine synthetase (GspS) in Crithidia fasciculata | Bioorg Med Chem Lett 12: 2703-5 (2002) BindingDB Entry DOI: 10.7270/Q2MS3S34 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Glutathionylspermidine synthase (Crithidia fasciculata) | BDBM50118641 (6-Amino-2-[(S)-2-((S)-4-amino-4-carboxy-butyrylami...) | KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL KEGG PC cid PC sid UniChem Similars | PubMed | 2.70E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Antwerp (UIA) Curated by ChEMBL | Assay Description Inhibitory constant of the compound was tested against glutathionylspermidine synthetase (GspS) in Crithidia fasciculata | Bioorg Med Chem Lett 12: 2703-5 (2002) BindingDB Entry DOI: 10.7270/Q2MS3S34 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Glutathionylspermidine synthase (Crithidia fasciculata) | BDBM50118641 (6-Amino-2-[(S)-2-((S)-4-amino-4-carboxy-butyrylami...) | KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL KEGG PC cid PC sid UniChem Similars | PubMed | 2.70E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Antwerp (UIA) Curated by ChEMBL | Assay Description Inhibitory constant of the compound was tested against glutathionylspermidine synthetase (GspS) in Crithidia fasciculata | Bioorg Med Chem Lett 12: 2703-5 (2002) BindingDB Entry DOI: 10.7270/Q2MS3S34 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Glutathionylspermidine synthase (Crithidia fasciculata) | BDBM50118639 (6-(4-Amino-butylamino)-2-[(S)-2-((S)-4-amino-4-car...) | KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL KEGG PC cid PC sid UniChem Similars | PubMed | 3.20E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Antwerp (UIA) Curated by ChEMBL | Assay Description Inhibitory constant of the compound was tested against glutathionylspermidine synthetase (GspS) in Crithidia fasciculata | Bioorg Med Chem Lett 12: 2703-5 (2002) BindingDB Entry DOI: 10.7270/Q2MS3S34 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Glutathionylspermidine synthase (Crithidia fasciculata) | BDBM50118639 (6-(4-Amino-butylamino)-2-[(S)-2-((S)-4-amino-4-car...) | KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL KEGG PC cid PC sid UniChem Similars | PubMed | 3.20E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Antwerp (UIA) Curated by ChEMBL | Assay Description Inhibitory constant of the compound was tested against glutathionylspermidine synthetase (GspS) in Crithidia fasciculata | Bioorg Med Chem Lett 12: 2703-5 (2002) BindingDB Entry DOI: 10.7270/Q2MS3S34 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Glutathionylspermidine synthase (Crithidia fasciculata) | BDBM50118645 (2-[(S)-2-((S)-4-Amino-4-carboxy-butyrylamino)-4-me...) | KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL KEGG PC cid PC sid UniChem Similars | PubMed | 3.30E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Antwerp (UIA) Curated by ChEMBL | Assay Description Tested against glutathionylspermidine synthetase (GspS) in Crithidia fasciculata | Bioorg Med Chem Lett 12: 2703-5 (2002) BindingDB Entry DOI: 10.7270/Q2MS3S34 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Glutathionylspermidine synthase (Crithidia fasciculata) | BDBM50118645 (2-[(S)-2-((S)-4-Amino-4-carboxy-butyrylamino)-4-me...) | KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL KEGG PC cid PC sid UniChem Similars | PubMed | 3.30E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Antwerp (UIA) Curated by ChEMBL | Assay Description Inhibitory constant of the compound was tested against glutathionylspermidine synthetase (GspS) in Crithidia fasciculata | Bioorg Med Chem Lett 12: 2703-5 (2002) BindingDB Entry DOI: 10.7270/Q2MS3S34 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Glutathionylspermidine synthase (Crithidia fasciculata) | BDBM50117547 (2-Amino-4-[3-methyl-1-(phosphonomethyl-carbamoyl)-...) | KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL KEGG PC cid PC sid UniChem Similars | PubMed | 6.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Antwerp (UIA) Curated by ChEMBL | Assay Description Inhibition constant of the compound was evaluated against enzyme Glutathionylspermidine Synthetase wild-type enzyme | Bioorg Med Chem Lett 12: 2553-6 (2002) BindingDB Entry DOI: 10.7270/Q2057F8Z | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Glutathionylspermidine synthase (Crithidia fasciculata) | BDBM50117544 (2-amino-4-(1-dihydroxyboronylmethylcarbamoyl-3-met...) | KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL KEGG PC cid PC sid UniChem | PubMed | 8.10E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Antwerp (UIA) Curated by ChEMBL | Assay Description Inhibition constant of the compound was evaluated against enzyme Glutathionylspermidine Synthetase wild-type enzyme | Bioorg Med Chem Lett 12: 2553-6 (2002) BindingDB Entry DOI: 10.7270/Q2057F8Z | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Glutathionylspermidine synthase (Crithidia fasciculata) | BDBM50117544 (2-amino-4-(1-dihydroxyboronylmethylcarbamoyl-3-met...) | KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL KEGG PC cid PC sid UniChem | PubMed | 8.10E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Antwerp (UIA) Curated by ChEMBL | Assay Description Concentration of the compound required for the inhibition of enzyme Glutathionylspermidine Synthetase wild-type enzyme | Bioorg Med Chem Lett 12: 2553-6 (2002) BindingDB Entry DOI: 10.7270/Q2057F8Z | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Integrase (Human immunodeficiency virus 1) | BDBM50410310 (CHEMBL2079773) | PDB MMDB UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet | Purchase CHEMBL MCE PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 10 | n/a | n/a | n/a | n/a | n/a | n/a |
Tibotec BVBA Curated by ChEMBL | Assay Description Inhibitory concentration against human immunodeficiency virus type 1 integrase | J Med Chem 48: 1930-40 (2005) Article DOI: 10.1021/jm049559q BindingDB Entry DOI: 10.7270/Q29Z94FZ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Genome polyprotein [2420-3010] (Hepatitis C virus genotype 1b (isolate Con1) (HCV)) | BDBM243470 (US9427440, 18) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid PDB UniChem | PDB US Patent | n/a | n/a | 26 | n/a | n/a | n/a | n/a | n/a | 25 |
Janssen Sciences Ireland UC US Patent | Assay Description IC50 con1b were determined according to the method as described previously (Pauwels et al, 2007, J Virol 81:6909-19) using a primer-dependent transcr... | US Patent US9427440 (2016) BindingDB Entry DOI: 10.7270/Q2DN43Z6 | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (crystal) | ||||||||||||
Genome polyprotein [2420-3010] (Hepatitis C virus genotype 1b (isolate Con1) (HCV)) | BDBM243471 (US9427440, 19) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 31 | n/a | n/a | n/a | n/a | n/a | 25 |
Janssen Sciences Ireland UC US Patent | Assay Description IC50 con1b were determined according to the method as described previously (Pauwels et al, 2007, J Virol 81:6909-19) using a primer-dependent transcr... | US Patent US9427440 (2016) BindingDB Entry DOI: 10.7270/Q2DN43Z6 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Genome polyprotein [2420-3010] (Hepatitis C virus genotype 1b (isolate Con1) (HCV)) | BDBM243456 (US9427440, 1) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | Purchase MCE PC cid PC sid UniChem | US Patent | n/a | n/a | 38 | n/a | n/a | n/a | n/a | n/a | 25 |
Janssen Sciences Ireland UC US Patent | Assay Description IC50 con1b were determined according to the method as described previously (Pauwels et al, 2007, J Virol 81:6909-19) using a primer-dependent transcr... | US Patent US9427440 (2016) BindingDB Entry DOI: 10.7270/Q2DN43Z6 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Genome polyprotein [2420-3010] (Hepatitis C virus genotype 1b (isolate Con1) (HCV)) | BDBM243472 (US9427440, 20) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 38 | n/a | n/a | n/a | n/a | n/a | 25 |
Janssen Sciences Ireland UC US Patent | Assay Description IC50 con1b were determined according to the method as described previously (Pauwels et al, 2007, J Virol 81:6909-19) using a primer-dependent transcr... | US Patent US9427440 (2016) BindingDB Entry DOI: 10.7270/Q2DN43Z6 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Genome polyprotein [2420-3010] (Hepatitis C virus genotype 1b (isolate Con1) (HCV)) | BDBM243468 (US9427440, 16) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 40 | n/a | n/a | n/a | n/a | n/a | 25 |
Janssen Sciences Ireland UC US Patent | Assay Description IC50 con1b were determined according to the method as described previously (Pauwels et al, 2007, J Virol 81:6909-19) using a primer-dependent transcr... | US Patent US9427440 (2016) BindingDB Entry DOI: 10.7270/Q2DN43Z6 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Integrase (Human immunodeficiency virus 1) | BDBM50410311 (CHEMBL2068731) | PDB MMDB UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet | CHEMBL KEGG PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 50 | n/a | n/a | n/a | n/a | n/a | n/a |
Tibotec BVBA Curated by ChEMBL | Assay Description Inhibitory concentration against human immunodeficiency virus type 1 integrase | J Med Chem 48: 1930-40 (2005) Article DOI: 10.1021/jm049559q BindingDB Entry DOI: 10.7270/Q29Z94FZ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Integrase (Human immunodeficiency virus 1) | BDBM50422732 (CHEMBL424782) | PDB MMDB UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 112 | n/a | n/a | n/a | n/a | n/a | n/a |
Tibotec BVBA Curated by ChEMBL | Assay Description Log of inhibitory concentration against human immunodeficiency virus type 1 integrase | J Med Chem 48: 1930-40 (2005) Article DOI: 10.1021/jm049559q BindingDB Entry DOI: 10.7270/Q29Z94FZ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Integrase (Human immunodeficiency virus 1) | BDBM50422734 (CHEMBL368301) | PDB MMDB UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 178 | n/a | n/a | n/a | n/a | n/a | n/a |
Tibotec BVBA Curated by ChEMBL | Assay Description Log of inhibitory concentration against human immunodeficiency virus type 1 integrase | J Med Chem 48: 1930-40 (2005) Article DOI: 10.1021/jm049559q BindingDB Entry DOI: 10.7270/Q29Z94FZ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Integrase (Human immunodeficiency virus 1) | BDBM50422722 (CHEMBL360752) | PDB MMDB UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 186 | n/a | n/a | n/a | n/a | n/a | n/a |
Tibotec BVBA Curated by ChEMBL | Assay Description Log of inhibitory concentration against human immunodeficiency virus type 1 integrase | J Med Chem 48: 1930-40 (2005) Article DOI: 10.1021/jm049559q BindingDB Entry DOI: 10.7270/Q29Z94FZ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Genome polyprotein [2420-3010] (Hepatitis C virus genotype 1b (strain HC-J4) (HCV)) | BDBM243461 (US9427440, 13) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 190 | n/a | n/a | n/a | n/a | 7.5 | 25 |
Janssen Sciences Ireland UC US Patent | Assay Description Measurement of HCV NS5B polymerization activity was performed by evaluating the amount of radiolabeled GTP incorporated by the enzyme in a newly synt... | US Patent US9427440 (2016) BindingDB Entry DOI: 10.7270/Q2DN43Z6 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Integrase (Human immunodeficiency virus 1) | BDBM50422731 (CHEMBL425516) | PDB MMDB UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 209 | n/a | n/a | n/a | n/a | n/a | n/a |
Tibotec BVBA Curated by ChEMBL | Assay Description Log of inhibitory concentration against human immunodeficiency virus type 1 integrase | J Med Chem 48: 1930-40 (2005) Article DOI: 10.1021/jm049559q BindingDB Entry DOI: 10.7270/Q29Z94FZ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Integrase (Human immunodeficiency virus 1) | BDBM50422706 (CHEMBL367104) | PDB MMDB UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 219 | n/a | n/a | n/a | n/a | n/a | n/a |
Tibotec BVBA Curated by ChEMBL | Assay Description Log of inhibitory concentration against human immunodeficiency virus type 1 integrase | J Med Chem 48: 1930-40 (2005) Article DOI: 10.1021/jm049559q BindingDB Entry DOI: 10.7270/Q29Z94FZ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Genome polyprotein [2420-3010] (Hepatitis C virus genotype 1b (strain HC-J4) (HCV)) | BDBM243457 (US9427440, 11) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 220 | n/a | n/a | n/a | n/a | 7.5 | 25 |
Janssen Sciences Ireland UC US Patent | Assay Description Measurement of HCV NS5B polymerization activity was performed by evaluating the amount of radiolabeled GTP incorporated by the enzyme in a newly synt... | US Patent US9427440 (2016) BindingDB Entry DOI: 10.7270/Q2DN43Z6 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Genome polyprotein [2420-3010] (Hepatitis C virus genotype 1b (strain HC-J4) (HCV)) | BDBM243456 (US9427440, 1) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | Purchase MCE PC cid PC sid UniChem | US Patent | n/a | n/a | 240 | n/a | n/a | n/a | n/a | 7.5 | 25 |
Janssen Sciences Ireland UC US Patent | Assay Description Measurement of HCV NS5B polymerization activity was performed by evaluating the amount of radiolabeled GTP incorporated by the enzyme in a newly synt... | US Patent US9427440 (2016) BindingDB Entry DOI: 10.7270/Q2DN43Z6 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Integrase (Human immunodeficiency virus 1) | BDBM50422718 (CHEMBL177640) | PDB MMDB UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 257 | n/a | n/a | n/a | n/a | n/a | n/a |
Tibotec BVBA Curated by ChEMBL | Assay Description Log of inhibitory concentration against human immunodeficiency virus type 1 integrase | J Med Chem 48: 1930-40 (2005) Article DOI: 10.1021/jm049559q BindingDB Entry DOI: 10.7270/Q29Z94FZ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Genome polyprotein [2420-3010] (Hepatitis C virus genotype 1b (strain HC-J4) (HCV)) | BDBM243460 (US9427440, 10) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 280 | n/a | n/a | n/a | n/a | 7.5 | 25 |
Janssen Sciences Ireland UC US Patent | Assay Description Measurement of HCV NS5B polymerization activity was performed by evaluating the amount of radiolabeled GTP incorporated by the enzyme in a newly synt... | US Patent US9427440 (2016) BindingDB Entry DOI: 10.7270/Q2DN43Z6 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Genome polyprotein [2420-3010] (Hepatitis C virus genotype 1b (strain HC-J4) (HCV)) | BDBM243458 (US9427440, 5) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 290 | n/a | n/a | n/a | n/a | 7.5 | 25 |
Janssen Sciences Ireland UC US Patent | Assay Description Measurement of HCV NS5B polymerization activity was performed by evaluating the amount of radiolabeled GTP incorporated by the enzyme in a newly synt... | US Patent US9427440 (2016) BindingDB Entry DOI: 10.7270/Q2DN43Z6 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Integrase (Human immunodeficiency virus 1) | BDBM50422733 (CHEMBL414654) | PDB MMDB UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 355 | n/a | n/a | n/a | n/a | n/a | n/a |
Tibotec BVBA Curated by ChEMBL | Assay Description Log of inhibitory concentration against human immunodeficiency virus type 1 integrase | J Med Chem 48: 1930-40 (2005) Article DOI: 10.1021/jm049559q BindingDB Entry DOI: 10.7270/Q29Z94FZ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Integrase (Human immunodeficiency virus 1) | BDBM50422697 (CHEMBL362252) | PDB MMDB UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 372 | n/a | n/a | n/a | n/a | n/a | n/a |
Tibotec BVBA Curated by ChEMBL | Assay Description Log of inhibitory concentration against human immunodeficiency virus type 1 integrase | J Med Chem 48: 1930-40 (2005) Article DOI: 10.1021/jm049559q BindingDB Entry DOI: 10.7270/Q29Z94FZ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Integrase (Human immunodeficiency virus 1) | BDBM50422703 (CHEMBL366982) | PDB MMDB UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 380 | n/a | n/a | n/a | n/a | n/a | n/a |
Tibotec BVBA Curated by ChEMBL | Assay Description Log of inhibitory concentration against human immunodeficiency virus type 1 integrase | J Med Chem 48: 1930-40 (2005) Article DOI: 10.1021/jm049559q BindingDB Entry DOI: 10.7270/Q29Z94FZ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Genome polyprotein [2420-3010] (Hepatitis C virus genotype 1b (strain HC-J4) (HCV)) | BDBM243455 (US9427440, 2) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 410 | n/a | n/a | n/a | n/a | 7.5 | 25 |
Janssen Sciences Ireland UC US Patent | Assay Description Measurement of HCV NS5B polymerization activity was performed by evaluating the amount of radiolabeled GTP incorporated by the enzyme in a newly synt... | US Patent US9427440 (2016) BindingDB Entry DOI: 10.7270/Q2DN43Z6 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Integrase (Human immunodeficiency virus 1) | BDBM50422699 (CHEMBL369841) | PDB MMDB UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 417 | n/a | n/a | n/a | n/a | n/a | n/a |
Tibotec BVBA Curated by ChEMBL | Assay Description Log of inhibitory concentration against human immunodeficiency virus type 1 integrase | J Med Chem 48: 1930-40 (2005) Article DOI: 10.1021/jm049559q BindingDB Entry DOI: 10.7270/Q29Z94FZ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Integrase (Human immunodeficiency virus 1) | BDBM50422711 (CHEMBL360274) | PDB MMDB UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 417 | n/a | n/a | n/a | n/a | n/a | n/a |
Tibotec BVBA Curated by ChEMBL | Assay Description Log of inhibitory concentration against human immunodeficiency virus type 1 integrase | J Med Chem 48: 1930-40 (2005) Article DOI: 10.1021/jm049559q BindingDB Entry DOI: 10.7270/Q29Z94FZ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Integrase (Human immunodeficiency virus 1) | BDBM50422700 (CHEMBL177515) | PDB MMDB UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 427 | n/a | n/a | n/a | n/a | n/a | n/a |
Tibotec BVBA Curated by ChEMBL | Assay Description Log of inhibitory concentration against human immunodeficiency virus type 1 integrase | J Med Chem 48: 1930-40 (2005) Article DOI: 10.1021/jm049559q BindingDB Entry DOI: 10.7270/Q29Z94FZ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Integrase (Human immunodeficiency virus 1) | BDBM50422704 (CHEMBL177215) | PDB MMDB UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 427 | n/a | n/a | n/a | n/a | n/a | n/a |
Tibotec BVBA Curated by ChEMBL | Assay Description Log of inhibitory concentration against human immunodeficiency virus type 1 integrase | J Med Chem 48: 1930-40 (2005) Article DOI: 10.1021/jm049559q BindingDB Entry DOI: 10.7270/Q29Z94FZ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Integrase (Human immunodeficiency virus 1) | BDBM50422721 (CHEMBL177622) | PDB MMDB UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 427 | n/a | n/a | n/a | n/a | n/a | n/a |
Tibotec BVBA Curated by ChEMBL | Assay Description Log of inhibitory concentration against human immunodeficiency virus type 1 integrase | J Med Chem 48: 1930-40 (2005) Article DOI: 10.1021/jm049559q BindingDB Entry DOI: 10.7270/Q29Z94FZ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Integrase (Human immunodeficiency virus 1) | BDBM50422728 (CHEMBL424780) | PDB MMDB UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 437 | n/a | n/a | n/a | n/a | n/a | n/a |
Tibotec BVBA Curated by ChEMBL | Assay Description Log of inhibitory concentration against human immunodeficiency virus type 1 integrase | J Med Chem 48: 1930-40 (2005) Article DOI: 10.1021/jm049559q BindingDB Entry DOI: 10.7270/Q29Z94FZ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Integrase (Human immunodeficiency virus 1) | BDBM50422702 (CHEMBL174793) | PDB MMDB UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 501 | n/a | n/a | n/a | n/a | n/a | n/a |
Tibotec BVBA Curated by ChEMBL | Assay Description Log of inhibitory concentration against human immunodeficiency virus type 1 integrase | J Med Chem 48: 1930-40 (2005) Article DOI: 10.1021/jm049559q BindingDB Entry DOI: 10.7270/Q29Z94FZ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Genome polyprotein [2420-3010] (Hepatitis C virus genotype 1b (isolate Con1) (HCV)) | BDBM243462 (US9427440, 3) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 530 | n/a | n/a | n/a | n/a | n/a | 25 |
Janssen Sciences Ireland UC US Patent | Assay Description IC50 con1b were determined according to the method as described previously (Pauwels et al, 2007, J Virol 81:6909-19) using a primer-dependent transcr... | US Patent US9427440 (2016) BindingDB Entry DOI: 10.7270/Q2DN43Z6 | |||||||||||
More data for this Ligand-Target Pair |
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