Compile Data Set for Download or QSAR

Found 26 hits with Last Name = 'andersen' and Initial = 'tl'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Neutrophil elastase (Homo sapiens (Human))	BDBM50398075 (CHEMBL2182012) Show SMILES CCCCNC(=O)CC[Si](O)(O)[C@@H](CC(C)C)NC(=O)[C@@H](NC(=O)Cc1ccc2ccccc2c1)[C@@H](C)CC |r| Show InChI InChI=1S/C30H47N3O5Si/c1-6-8-16-31-26(34)15-17-39(37,38)28(18-21(3)4)33-30(36)29(22(5)7-2)32-27(35)20-23-13-14-24-11-9-10-12-25(24)19-23/h9-14,19,21-22,28-29,37-38H,6-8,15-18,20H2,1-5H3,(H,31,34)(H,32,35)(H,33,36)/t22-,28-,29-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	3.50E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Aarhus University Curated by ChEMBL					Assay Description Uncompetitive inhibition of human neutrophil elastase assessed as hydrolysis of N-succinyl-Ala-Ala-Pro-Val-p-nitroanilide incubated for 2 hrs measure...				J Med Chem 55: 7900-8 (2012) Article DOI: 10.1021/jm301000k BindingDB Entry DOI: 10.7270/Q2B27WD6
					More data for this Ligand-Target Pair
Neutrophil elastase (Homo sapiens (Human))	BDBM50398081 (CHEMBL2182013) Show SMILES CCCCNC(=O)CC[Si](O)(O)[C@H](CC(C)C)NC(=O)[C@@H](NC(=O)c1ccc2ccccc2c1)[C@@H](C)CC |r| Show InChI InChI=1S/C29H45N3O5Si/c1-6-8-16-30-25(33)15-17-38(36,37)26(18-20(3)4)31-29(35)27(21(5)7-2)32-28(34)24-14-13-22-11-9-10-12-23(22)19-24/h9-14,19-21,26-27,36-37H,6-8,15-18H2,1-5H3,(H,30,33)(H,31,35)(H,32,34)/t21-,26+,27-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	4.00E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Aarhus University Curated by ChEMBL					Assay Description Uncompetitive inhibition of human neutrophil elastase assessed as hydrolysis of N-succinyl-Ala-Ala-Pro-Val-p-nitroanilide incubated for 2 hrs measure...				J Med Chem 55: 7900-8 (2012) Article DOI: 10.1021/jm301000k BindingDB Entry DOI: 10.7270/Q2B27WD6
					More data for this Ligand-Target Pair
Neutrophil elastase (Homo sapiens (Human))	BDBM50398080 (CHEMBL2182014) Show SMILES CCCCNC(=O)CC[Si](O)(O)[C@H](CC(C)C)NC(=O)[C@@H](NC(=O)Cc1ccccc1)[C@@H](C)CC |r| Show InChI InChI=1S/C26H45N3O5Si/c1-6-8-15-27-22(30)14-16-35(33,34)24(17-19(3)4)29-26(32)25(20(5)7-2)28-23(31)18-21-12-10-9-11-13-21/h9-13,19-20,24-25,33-34H,6-8,14-18H2,1-5H3,(H,27,30)(H,28,31)(H,29,32)/t20-,24+,25-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	5.00E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Aarhus University Curated by ChEMBL					Assay Description Uncompetitive inhibition of human neutrophil elastase assessed as hydrolysis of N-succinyl-Ala-Ala-Pro-Val-p-nitroanilide incubated for 2 hrs measure...				J Med Chem 55: 7900-8 (2012) Article DOI: 10.1021/jm301000k BindingDB Entry DOI: 10.7270/Q2B27WD6
					More data for this Ligand-Target Pair
Neutrophil elastase (Homo sapiens (Human))	BDBM50398079 (CHEMBL2182018) Show SMILES CCCCNC(=O)CC[Si]([C@H](CC(C)C)NC(=O)[C@@H](NC(=O)Cc1ccc2ccccc2c1)[C@@H](C)CC)(c1ccccc1)c1ccccc1 |r| Show InChI InChI=1S/C42H55N3O3Si/c1-6-8-26-43-38(46)25-27-49(36-19-11-9-12-20-36,37-21-13-10-14-22-37)40(28-31(3)4)45-42(48)41(32(5)7-2)44-39(47)30-33-23-24-34-17-15-16-18-35(34)29-33/h9-24,29,31-32,40-41H,6-8,25-28,30H2,1-5H3,(H,43,46)(H,44,47)(H,45,48)/t32-,40+,41-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	1.30E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Aarhus University Curated by ChEMBL					Assay Description Noncompetitive inhibition of human neutrophil elastase assessed as hydrolysis of N-succinyl-Ala-Ala-Pro-Val-p-nitroanilide incubated for 2 hrs measur...				J Med Chem 55: 7900-8 (2012) Article DOI: 10.1021/jm301000k BindingDB Entry DOI: 10.7270/Q2B27WD6
					More data for this Ligand-Target Pair
Neutrophil elastase (Homo sapiens (Human))	BDBM50398078 (CHEMBL2182019) Show SMILES CCCCNC(=O)CNC(=O)[C@H](CC(C)C)NC(=O)[C@@H](NC(=O)Cc1ccc2ccccc2c1)[C@@H](C)CC |r| Show InChI InChI=1S/C30H44N4O4/c1-6-8-15-31-27(36)19-32-29(37)25(16-20(3)4)33-30(38)28(21(5)7-2)34-26(35)18-22-13-14-23-11-9-10-12-24(23)17-22/h9-14,17,20-21,25,28H,6-8,15-16,18-19H2,1-5H3,(H,31,36)(H,32,37)(H,33,38)(H,34,35)/t21-,25-,28-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.80E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Aarhus University Curated by ChEMBL					Assay Description Noncompetitive inhibition of human neutrophil elastase assessed as hydrolysis of N-succinyl-Ala-Ala-Pro-Val-p-nitroanilide incubated for 2 hrs measur...				J Med Chem 55: 7900-8 (2012) Article DOI: 10.1021/jm301000k BindingDB Entry DOI: 10.7270/Q2B27WD6
					More data for this Ligand-Target Pair
Angiotensin-converting enzyme (Homo sapiens (Human))	BDBM50398088 (CHEMBL2097001) Show SMILES C[C@H](C[Si](O)(O)[C@H](Cc1ccccc1)NC(=O)c1ccccc1)C(=O)N1CCC[C@H]1C(O)=O Show InChI InChI=1S/C24H30N2O6Si/c1-17(23(28)26-14-8-13-20(26)24(29)30)16-33(31,32)21(15-18-9-4-2-5-10-18)25-22(27)19-11-6-3-7-12-19/h2-7,9-12,17,20-21,31-32H,8,13-16H2,1H3,(H,25,27)(H,29,30)/t17-,20+,21-/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.80	n/a	n/a	n/a	n/a	n/a	n/a
Aarhus University Curated by ChEMBL					Assay Description Inhibition of ACE				J Med Chem 55: 7900-8 (2012) Article DOI: 10.1021/jm301000k BindingDB Entry DOI: 10.7270/Q2B27WD6
					More data for this Ligand-Target Pair
Neutrophil elastase (Homo sapiens (Human))	BDBM50398075 (CHEMBL2182012) Show SMILES CCCCNC(=O)CC[Si](O)(O)[C@@H](CC(C)C)NC(=O)[C@@H](NC(=O)Cc1ccc2ccccc2c1)[C@@H](C)CC |r| Show InChI InChI=1S/C30H47N3O5Si/c1-6-8-16-31-26(34)15-17-39(37,38)28(18-21(3)4)33-30(36)29(22(5)7-2)32-27(35)20-23-13-14-24-11-9-10-12-25(24)19-23/h9-14,19,21-22,28-29,37-38H,6-8,15-18,20H2,1-5H3,(H,31,34)(H,32,35)(H,33,36)/t22-,28-,29-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	300	n/a	n/a	n/a	n/a	n/a	n/a
Aarhus University Curated by ChEMBL					Assay Description Inhibition of human neutrophil elastase				J Med Chem 55: 7900-8 (2012) Article DOI: 10.1021/jm301000k BindingDB Entry DOI: 10.7270/Q2B27WD6
					More data for this Ligand-Target Pair
Neutrophil elastase (Homo sapiens (Human))	BDBM50398076 (CHEMBL2182011) Show SMILES CCCCNC(=O)CC[Si](O)(O)[C@H](CC(C)C)NC(=O)[C@@H](NC(=O)Cc1ccc2ccccc2c1)[C@@H](C)CC |r| Show InChI InChI=1S/C30H47N3O5Si/c1-6-8-16-31-26(34)15-17-39(37,38)28(18-21(3)4)33-30(36)29(22(5)7-2)32-27(35)20-23-13-14-24-11-9-10-12-25(24)19-23/h9-14,19,21-22,28-29,37-38H,6-8,15-18,20H2,1-5H3,(H,31,34)(H,32,35)(H,33,36)/t22-,28+,29-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	300	n/a	n/a	n/a	n/a	n/a	n/a
Aarhus University Curated by ChEMBL					Assay Description Inhibition of human neutrophil elastase				J Med Chem 55: 7900-8 (2012) Article DOI: 10.1021/jm301000k BindingDB Entry DOI: 10.7270/Q2B27WD6
					More data for this Ligand-Target Pair
Neutrophil elastase (Homo sapiens (Human))	BDBM50398078 (CHEMBL2182019) Show SMILES CCCCNC(=O)CNC(=O)[C@H](CC(C)C)NC(=O)[C@@H](NC(=O)Cc1ccc2ccccc2c1)[C@@H](C)CC |r| Show InChI InChI=1S/C30H44N4O4/c1-6-8-15-31-27(36)19-32-29(37)25(16-20(3)4)33-30(38)28(21(5)7-2)34-26(35)18-22-13-14-23-11-9-10-12-24(23)17-22/h9-14,17,20-21,25,28H,6-8,15-16,18-19H2,1-5H3,(H,31,36)(H,32,37)(H,33,38)(H,34,35)/t21-,25-,28-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.40E+4	n/a	n/a	n/a	n/a	n/a	n/a
Aarhus University Curated by ChEMBL					Assay Description Inhibition of human neutrophil elastase assessed as hydrolysis of N-succinyl-Ala-Ala-Pro-Val-p-nitroanilide incubated for 2 hrs measured for 20 mins ...				J Med Chem 55: 7900-8 (2012) Article DOI: 10.1021/jm301000k BindingDB Entry DOI: 10.7270/Q2B27WD6
					More data for this Ligand-Target Pair
Neutrophil elastase (Homo sapiens (Human))	BDBM50398079 (CHEMBL2182018) Show SMILES CCCCNC(=O)CC[Si]([C@H](CC(C)C)NC(=O)[C@@H](NC(=O)Cc1ccc2ccccc2c1)[C@@H](C)CC)(c1ccccc1)c1ccccc1 |r| Show InChI InChI=1S/C42H55N3O3Si/c1-6-8-26-43-38(46)25-27-49(36-19-11-9-12-20-36,37-21-13-10-14-22-37)40(28-31(3)4)45-42(48)41(32(5)7-2)44-39(47)30-33-23-24-34-17-15-16-18-35(34)29-33/h9-24,29,31-32,40-41H,6-8,25-28,30H2,1-5H3,(H,43,46)(H,44,47)(H,45,48)/t32-,40+,41-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.40E+4	n/a	n/a	n/a	n/a	n/a	n/a
Aarhus University Curated by ChEMBL					Assay Description Inhibition of human neutrophil elastase assessed as hydrolysis of N-succinyl-Ala-Ala-Pro-Val-p-nitroanilide incubated for 2 hrs measured for 20 mins ...				J Med Chem 55: 7900-8 (2012) Article DOI: 10.1021/jm301000k BindingDB Entry DOI: 10.7270/Q2B27WD6
					More data for this Ligand-Target Pair
Neutrophil elastase (Homo sapiens (Human))	BDBM50398081 (CHEMBL2182013) Show SMILES CCCCNC(=O)CC[Si](O)(O)[C@H](CC(C)C)NC(=O)[C@@H](NC(=O)c1ccc2ccccc2c1)[C@@H](C)CC |r| Show InChI InChI=1S/C29H45N3O5Si/c1-6-8-16-30-25(33)15-17-38(36,37)26(18-20(3)4)31-29(35)27(21(5)7-2)32-28(34)24-14-13-22-11-9-10-12-23(22)19-24/h9-14,19-21,26-27,36-37H,6-8,15-18H2,1-5H3,(H,30,33)(H,31,35)(H,32,34)/t21-,26+,27-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.60E+4	n/a	n/a	n/a	n/a	n/a	n/a
Aarhus University Curated by ChEMBL					Assay Description Inhibition of human neutrophil elastase assessed as hydrolysis of N-succinyl-Ala-Ala-Pro-Val-p-nitroanilide incubated for 2 hrs measured for 20 mins ...				J Med Chem 55: 7900-8 (2012) Article DOI: 10.1021/jm301000k BindingDB Entry DOI: 10.7270/Q2B27WD6
					More data for this Ligand-Target Pair
Neutrophil elastase (Homo sapiens (Human))	BDBM50398075 (CHEMBL2182012) Show SMILES CCCCNC(=O)CC[Si](O)(O)[C@@H](CC(C)C)NC(=O)[C@@H](NC(=O)Cc1ccc2ccccc2c1)[C@@H](C)CC |r| Show InChI InChI=1S/C30H47N3O5Si/c1-6-8-16-31-26(34)15-17-39(37,38)28(18-21(3)4)33-30(36)29(22(5)7-2)32-27(35)20-23-13-14-24-11-9-10-12-25(24)19-23/h9-14,19,21-22,28-29,37-38H,6-8,15-18,20H2,1-5H3,(H,31,34)(H,32,35)(H,33,36)/t22-,28-,29-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.80E+4	n/a	n/a	n/a	n/a	n/a	n/a
Aarhus University Curated by ChEMBL					Assay Description Inhibition of human neutrophil elastase assessed as hydrolysis of N-succinyl-Ala-Ala-Pro-Val-p-nitroanilide incubated for 2 hrs measured for 20 mins ...				J Med Chem 55: 7900-8 (2012) Article DOI: 10.1021/jm301000k BindingDB Entry DOI: 10.7270/Q2B27WD6
					More data for this Ligand-Target Pair
Neutrophil elastase (Homo sapiens (Human))	BDBM50398080 (CHEMBL2182014) Show SMILES CCCCNC(=O)CC[Si](O)(O)[C@H](CC(C)C)NC(=O)[C@@H](NC(=O)Cc1ccccc1)[C@@H](C)CC |r| Show InChI InChI=1S/C26H45N3O5Si/c1-6-8-15-27-22(30)14-16-35(33,34)24(17-19(3)4)29-26(32)25(20(5)7-2)28-23(31)18-21-12-10-9-11-13-21/h9-13,19-20,24-25,33-34H,6-8,14-18H2,1-5H3,(H,27,30)(H,28,31)(H,29,32)/t20-,24+,25-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.80E+4	n/a	n/a	n/a	n/a	n/a	n/a
Aarhus University Curated by ChEMBL					Assay Description Inhibition of human neutrophil elastase assessed as hydrolysis of N-succinyl-Ala-Ala-Pro-Val-p-nitroanilide incubated for 2 hrs measured for 20 mins ...				J Med Chem 55: 7900-8 (2012) Article DOI: 10.1021/jm301000k BindingDB Entry DOI: 10.7270/Q2B27WD6
					More data for this Ligand-Target Pair
Neutrophil elastase (Homo sapiens (Human))	BDBM50398085 (CHEMBL2182017) Show SMILES CC[C@H](C)[C@H](NC(=O)Cc1ccc2ccccc2c1)C(=O)N[C@@H](CC(C)C)[Si](C)(O)O |r| Show InChI InChI=1S/C24H36N2O4Si/c1-6-17(4)23(24(28)26-22(13-16(2)3)31(5,29)30)25-21(27)15-18-11-12-19-9-7-8-10-20(19)14-18/h7-12,14,16-17,22-23,29-30H,6,13,15H2,1-5H3,(H,25,27)(H,26,28)/t17-,22+,23-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.90E+4	n/a	n/a	n/a	n/a	n/a	n/a
Aarhus University Curated by ChEMBL					Assay Description Inhibition of human neutrophil elastase assessed as hydrolysis of N-succinyl-Ala-Ala-Pro-Val-p-nitroanilide incubated for 2 hrs measured for 20 mins ...				J Med Chem 55: 7900-8 (2012) Article DOI: 10.1021/jm301000k BindingDB Entry DOI: 10.7270/Q2B27WD6
					More data for this Ligand-Target Pair
Neutrophil elastase (Homo sapiens (Human))	BDBM50398086 (CHEMBL2182016) Show SMILES CCCCNC(=O)CC[Si](O)(O)[C@H](CC(C)C)NC(=O)[C@@H](NC(=O)C(F)(F)F)[C@@H](C)CC |r| Show InChI InChI=1S/C20H38F3N3O5Si/c1-6-8-10-24-15(27)9-11-32(30,31)16(12-13(3)4)25-18(28)17(14(5)7-2)26-19(29)20(21,22)23/h13-14,16-17,30-31H,6-12H2,1-5H3,(H,24,27)(H,25,28)(H,26,29)/t14-,16+,17-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	4.60E+4	n/a	n/a	n/a	n/a	n/a	n/a
Aarhus University Curated by ChEMBL					Assay Description Inhibition of human neutrophil elastase assessed as hydrolysis of N-succinyl-Ala-Ala-Pro-Val-p-nitroanilide incubated for 2 hrs measured for 20 mins ...				J Med Chem 55: 7900-8 (2012) Article DOI: 10.1021/jm301000k BindingDB Entry DOI: 10.7270/Q2B27WD6
					More data for this Ligand-Target Pair
Neutrophil elastase (Homo sapiens (Human))	BDBM50398084 (CHEMBL2182020) Show SMILES CCCCNC(=O)CNC(=O)[C@H](CC(C)C)NC(=O)[C@@H](NC(=O)Cc1ccccc1)[C@@H](C)CC |r| Show InChI InChI=1S/C26H42N4O4/c1-6-8-14-27-23(32)17-28-25(33)21(15-18(3)4)29-26(34)24(19(5)7-2)30-22(31)16-20-12-10-9-11-13-20/h9-13,18-19,21,24H,6-8,14-17H2,1-5H3,(H,27,32)(H,28,33)(H,29,34)(H,30,31)/t19-,21-,24-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	5.10E+4	n/a	n/a	n/a	n/a	n/a	n/a
Aarhus University Curated by ChEMBL					Assay Description Inhibition of human neutrophil elastase assessed as hydrolysis of N-succinyl-Ala-Ala-Pro-Val-p-nitroanilide incubated for 2 hrs measured for 20 mins ...				J Med Chem 55: 7900-8 (2012) Article DOI: 10.1021/jm301000k BindingDB Entry DOI: 10.7270/Q2B27WD6
					More data for this Ligand-Target Pair
Prothrombin (Homo sapiens (Human))	BDBM50398077 (CHEMBL1256178) Show SMILES NCCc1ccc(cc1)S(F)(=O)=O Show InChI InChI=1S/C8H10FNO2S/c9-13(11,12)8-3-1-7(2-4-8)5-6-10/h1-4H,5-6,10H2	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE PC cid PC sid PDB UniChem	Article PubMed	n/a	n/a	6.20E+4	n/a	n/a	n/a	n/a	n/a	n/a
Aarhus University Curated by ChEMBL					Assay Description Inhibition of thrombin assessed as hydrolysis of H-D-Pro-L-Phe-L-Arg-p-nitroanilide incubated for 2 hrs measured for 20 mins by microplate reader ana...				J Med Chem 55: 7900-8 (2012) Article DOI: 10.1021/jm301000k BindingDB Entry DOI: 10.7270/Q2B27WD6
					More data for this Ligand-Target Pair
Prothrombin (Homo sapiens (Human))	BDBM50398079 (CHEMBL2182018) Show SMILES CCCCNC(=O)CC[Si]([C@H](CC(C)C)NC(=O)[C@@H](NC(=O)Cc1ccc2ccccc2c1)[C@@H](C)CC)(c1ccccc1)c1ccccc1 |r| Show InChI InChI=1S/C42H55N3O3Si/c1-6-8-26-43-38(46)25-27-49(36-19-11-9-12-20-36,37-21-13-10-14-22-37)40(28-31(3)4)45-42(48)41(32(5)7-2)44-39(47)30-33-23-24-34-17-15-16-18-35(34)29-33/h9-24,29,31-32,40-41H,6-8,25-28,30H2,1-5H3,(H,43,46)(H,44,47)(H,45,48)/t32-,40+,41-/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	9.20E+4	n/a	n/a	n/a	n/a	n/a	n/a
Aarhus University Curated by ChEMBL					Assay Description Inhibition of thrombin assessed as hydrolysis of H-D-Pro-L-Phe-L-Arg-p-nitroanilide incubated for 2 hrs measured for 20 mins by microplate reader ana...				J Med Chem 55: 7900-8 (2012) Article DOI: 10.1021/jm301000k BindingDB Entry DOI: 10.7270/Q2B27WD6
					More data for this Ligand-Target Pair
Plasminogen (Homo sapiens (Human))	BDBM50398078 (CHEMBL2182019) Show SMILES CCCCNC(=O)CNC(=O)[C@H](CC(C)C)NC(=O)[C@@H](NC(=O)Cc1ccc2ccccc2c1)[C@@H](C)CC |r| Show InChI InChI=1S/C30H44N4O4/c1-6-8-15-31-27(36)19-32-29(37)25(16-20(3)4)33-30(38)28(21(5)7-2)34-26(35)18-22-13-14-23-11-9-10-12-24(23)17-22/h9-14,17,20-21,25,28H,6-8,15-16,18-19H2,1-5H3,(H,31,36)(H,32,37)(H,33,38)(H,34,35)/t21-,25-,28-/m0/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	9.90E+4	n/a	n/a	n/a	n/a	n/a	n/a
Aarhus University Curated by ChEMBL					Assay Description Inhibition of plasmin assessed as hydrolysis of H-D-Val-L-Leu-L-Lys-p-nitroanilide incubated for 2 hrs measured for 20 mins by microplate reader anal...				J Med Chem 55: 7900-8 (2012) Article DOI: 10.1021/jm301000k BindingDB Entry DOI: 10.7270/Q2B27WD6
					More data for this Ligand-Target Pair
Prothrombin (Homo sapiens (Human))	BDBM50398078 (CHEMBL2182019) Show SMILES CCCCNC(=O)CNC(=O)[C@H](CC(C)C)NC(=O)[C@@H](NC(=O)Cc1ccc2ccccc2c1)[C@@H](C)CC |r| Show InChI InChI=1S/C30H44N4O4/c1-6-8-15-31-27(36)19-32-29(37)25(16-20(3)4)33-30(38)28(21(5)7-2)34-26(35)18-22-13-14-23-11-9-10-12-24(23)17-22/h9-14,17,20-21,25,28H,6-8,15-16,18-19H2,1-5H3,(H,31,36)(H,32,37)(H,33,38)(H,34,35)/t21-,25-,28-/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
Aarhus University Curated by ChEMBL					Assay Description Inhibition of thrombin assessed as hydrolysis of H-D-Pro-L-Phe-L-Arg-p-nitroanilide incubated for 2 hrs measured for 20 mins by microplate reader ana...				J Med Chem 55: 7900-8 (2012) Article DOI: 10.1021/jm301000k BindingDB Entry DOI: 10.7270/Q2B27WD6
					More data for this Ligand-Target Pair
Cathepsin G (Homo sapiens (Human))	BDBM50398079 (CHEMBL2182018) Show SMILES CCCCNC(=O)CC[Si]([C@H](CC(C)C)NC(=O)[C@@H](NC(=O)Cc1ccc2ccccc2c1)[C@@H](C)CC)(c1ccccc1)c1ccccc1 |r| Show InChI InChI=1S/C42H55N3O3Si/c1-6-8-26-43-38(46)25-27-49(36-19-11-9-12-20-36,37-21-13-10-14-22-37)40(28-31(3)4)45-42(48)41(32(5)7-2)44-39(47)30-33-23-24-34-17-15-16-18-35(34)29-33/h9-24,29,31-32,40-41H,6-8,25-28,30H2,1-5H3,(H,43,46)(H,44,47)(H,45,48)/t32-,40+,41-/m0/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.20E+5	n/a	n/a	n/a	n/a	n/a	n/a
Aarhus University Curated by ChEMBL					Assay Description Inhibition of cathepsin G assessed as hydrolysis of N-succinyl-Ala-Ala-Pro-Phe-p-nitroanilide incubated for 2 hrs measured for 20 mins by microplate ...				J Med Chem 55: 7900-8 (2012) Article DOI: 10.1021/jm301000k BindingDB Entry DOI: 10.7270/Q2B27WD6
					More data for this Ligand-Target Pair
Neutrophil elastase (Homo sapiens (Human))	BDBM50398082 (CHEMBL2182022) Show SMILES CCCCNC(=O)CNC(=O)[C@H](CC(C)C)NC(=O)[C@@H](NC(=O)C(F)(F)F)[C@@H](C)CC |r| Show InChI InChI=1S/C20H35F3N4O4/c1-6-8-9-24-15(28)11-25-17(29)14(10-12(3)4)26-18(30)16(13(5)7-2)27-19(31)20(21,22)23/h12-14,16H,6-11H2,1-5H3,(H,24,28)(H,25,29)(H,26,30)(H,27,31)/t13-,14-,16-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	>2.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
Aarhus University Curated by ChEMBL					Assay Description Inhibition of human neutrophil elastase assessed as hydrolysis of N-succinyl-Ala-Ala-Pro-Val-p-nitroanilide incubated for 2 hrs measured for 20 mins ...				J Med Chem 55: 7900-8 (2012) Article DOI: 10.1021/jm301000k BindingDB Entry DOI: 10.7270/Q2B27WD6
					More data for this Ligand-Target Pair
Neutrophil elastase (Homo sapiens (Human))	BDBM50398087 (CHEMBL2182015) Show SMILES CCCCNC(=O)CC[Si](O)(O)[C@H](CC(C)C)NC(=O)[C@@H](NC(C)=O)[C@@H](C)CC |r| Show InChI InChI=1S/C20H41N3O5Si/c1-7-9-11-21-17(25)10-12-29(27,28)18(13-14(3)4)23-20(26)19(15(5)8-2)22-16(6)24/h14-15,18-19,27-28H,7-13H2,1-6H3,(H,21,25)(H,22,24)(H,23,26)/t15-,18+,19-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>2.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
Aarhus University Curated by ChEMBL					Assay Description Inhibition of human neutrophil elastase assessed as hydrolysis of N-succinyl-Ala-Ala-Pro-Val-p-nitroanilide incubated for 2 hrs measured for 20 mins ...				J Med Chem 55: 7900-8 (2012) Article DOI: 10.1021/jm301000k BindingDB Entry DOI: 10.7270/Q2B27WD6
					More data for this Ligand-Target Pair
Neutrophil elastase (Homo sapiens (Human))	BDBM50398083 (CHEMBL2182021) Show SMILES CCCCNC(=O)CNC(=O)[C@H](CC(C)C)NC(=O)[C@@H](NC(C)=O)[C@@H](C)CC |r| Show InChI InChI=1S/C20H38N4O4/c1-7-9-10-21-17(26)12-22-19(27)16(11-13(3)4)24-20(28)18(14(5)8-2)23-15(6)25/h13-14,16,18H,7-12H2,1-6H3,(H,21,26)(H,22,27)(H,23,25)(H,24,28)/t14-,16-,18-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>2.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
Aarhus University Curated by ChEMBL					Assay Description Inhibition of human neutrophil elastase assessed as hydrolysis of N-succinyl-Ala-Ala-Pro-Val-p-nitroanilide incubated for 2 hrs measured for 20 mins ...				J Med Chem 55: 7900-8 (2012) Article DOI: 10.1021/jm301000k BindingDB Entry DOI: 10.7270/Q2B27WD6
					More data for this Ligand-Target Pair
Plasminogen (Homo sapiens (Human))	BDBM50398077 (CHEMBL1256178) Show SMILES NCCc1ccc(cc1)S(F)(=O)=O Show InChI InChI=1S/C8H10FNO2S/c9-13(11,12)8-3-1-7(2-4-8)5-6-10/h1-4H,5-6,10H2	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE PC cid PC sid PDB UniChem	Article PubMed	n/a	n/a	2.40E+5	n/a	n/a	n/a	n/a	n/a	n/a
Aarhus University Curated by ChEMBL					Assay Description Inhibition of plasmin assessed as hydrolysis of H-D-Val-L-Leu-L-Lys-p-nitroanilide incubated for 2 hrs measured for 20 mins by microplate reader anal...				J Med Chem 55: 7900-8 (2012) Article DOI: 10.1021/jm301000k BindingDB Entry DOI: 10.7270/Q2B27WD6
					More data for this Ligand-Target Pair
Cathepsin G (Homo sapiens (Human))	BDBM50398077 (CHEMBL1256178) Show SMILES NCCc1ccc(cc1)S(F)(=O)=O Show InChI InChI=1S/C8H10FNO2S/c9-13(11,12)8-3-1-7(2-4-8)5-6-10/h1-4H,5-6,10H2	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE PC cid PC sid PDB UniChem	Article PubMed	n/a	n/a	2.50E+5	n/a	n/a	n/a	n/a	n/a	n/a
Aarhus University Curated by ChEMBL					Assay Description Inhibition of cathepsin G assessed as hydrolysis of N-succinyl-Ala-Ala-Pro-Phe-p-nitroanilide incubated for 2 hrs measured for 20 mins by microplate ...				J Med Chem 55: 7900-8 (2012) Article DOI: 10.1021/jm301000k BindingDB Entry DOI: 10.7270/Q2B27WD6
					More data for this Ligand-Target Pair