Compile Data Set for Download or QSAR

Found 133 hits with Last Name = 'anderson' and Initial = 've'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Serine/threonine-protein kinase Chk2 (Homo sapiens (Human))	BDBM50335684 (4-FLUORO-2-(4-{[(3S,4R)-4-(1-HYDROXY-1-METHYLETHYL...) Show SMILES COc1cc2nc(nc(N[C@@H]3CNC[C@H]3C(C)(C)O)c2cc1OC)-c1cc(F)ccc1O |r| Show InChI InChI=1S/C23H27FN4O4/c1-23(2,30)15-10-25-11-17(15)27-21-13-8-19(31-3)20(32-4)9-16(13)26-22(28-21)14-7-12(24)5-6-18(14)29/h5-9,15,17,25,29-30H,10-11H2,1-4H3,(H,26,27,28)/t15-,17-/m1/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE MMDB PC cid PC sid PDB UniChem Patents Similars	MMDB PDB Article PubMed	n/a	n/a	3	n/a	n/a	n/a	n/a	n/a	n/a
Institute of Cancer Research Curated by ChEMBL					Assay Description Inhibition of CHK2 by DELFIA assay				J Med Chem 54: 580-90 (2011) Article DOI: 10.1021/jm101150b BindingDB Entry DOI: 10.7270/Q2DF6RHX
					More data for this Ligand-Target Pair				3D Structure (crystal)
Serine/threonine-protein kinase Chk2 (Homo sapiens (Human))	BDBM50335683 (4-fluoro-2-(4-((3S,4R)-4-(2-hydroxypropan-2-yl)pyr...) Show SMILES COCCOc1cc2nc(nc(N[C@@H]3CNC[C@H]3C(C)(C)O)c2cc1OC)-c1cc(F)ccc1O |r| Show InChI InChI=1S/C25H31FN4O5/c1-25(2,32)17-12-27-13-19(17)29-23-15-10-21(34-4)22(35-8-7-33-3)11-18(15)28-24(30-23)16-9-14(26)5-6-20(16)31/h5-6,9-11,17,19,27,31-32H,7-8,12-13H2,1-4H3,(H,28,29,30)/t17-,19-/m1/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	5	n/a	n/a	n/a	n/a	n/a	n/a
Institute of Cancer Research Curated by ChEMBL					Assay Description Inhibition of CHK2 by DELFIA assay				J Med Chem 54: 580-90 (2011) Article DOI: 10.1021/jm101150b BindingDB Entry DOI: 10.7270/Q2DF6RHX
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase Chk2 (Homo sapiens (Human))	BDBM50335687 (2-(4-((3S,4R)-4-(2-hydroxypropan-2-yl)pyrrolidin-3...) Show SMILES CC(C)(O)[C@@H]1CNC[C@H]1Nc1nc(nc2ccccc12)-c1cc(ccc1O)-c1cc[nH]n1 |r| Show InChI InChI=1S/C24H26N6O2/c1-24(2,32)17-12-25-13-20(17)28-22-15-5-3-4-6-19(15)27-23(29-22)16-11-14(7-8-21(16)31)18-9-10-26-30-18/h3-11,17,20,25,31-32H,12-13H2,1-2H3,(H,26,30)(H,27,28,29)/t17-,20-/m1/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	8	n/a	n/a	n/a	n/a	n/a	n/a
Institute of Cancer Research Curated by ChEMBL					Assay Description Inhibition of CHK2 by DELFIA assay				J Med Chem 54: 580-90 (2011) Article DOI: 10.1021/jm101150b BindingDB Entry DOI: 10.7270/Q2DF6RHX
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase Chk2 (Homo sapiens (Human))	BDBM50335662 ((S)-4-(1H-pyrazol-3-yl)-2-(4-(pyrrolidin-3-ylamino...) Show SMILES Oc1ccc(cc1-c1nc(N[C@H]2CCNC2)c2ccccc2n1)-c1cc[nH]n1 |r| Show InChI InChI=1S/C21H20N6O/c28-19-6-5-13(17-8-10-23-27-17)11-16(19)21-25-18-4-2-1-3-15(18)20(26-21)24-14-7-9-22-12-14/h1-6,8,10-11,14,22,28H,7,9,12H2,(H,23,27)(H,24,25,26)/t14-/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL MMDB PC cid PC sid UniChem Patents Similars	MMDB Article PubMed	n/a	n/a	9	n/a	n/a	n/a	n/a	n/a	n/a
Institute of Cancer Research Curated by ChEMBL					Assay Description Inhibition of CHK2 by DELFIA assay				J Med Chem 54: 580-90 (2011) Article DOI: 10.1021/jm101150b BindingDB Entry DOI: 10.7270/Q2DF6RHX
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase Chk2 (Homo sapiens (Human))	BDBM50335685 (4-fluoro-2-(4-((3S,4R)-4-(hydroxymethyl)pyrrolidin...) Show SMILES COc1cc2nc(nc(N[C@@H]3CNC[C@H]3CO)c2cc1OC)-c1cc(F)ccc1O |r| Show InChI InChI=1S/C21H23FN4O4/c1-29-18-6-13-15(7-19(18)30-2)24-21(14-5-12(22)3-4-17(14)28)26-20(13)25-16-9-23-8-11(16)10-27/h3-7,11,16,23,27-28H,8-10H2,1-2H3,(H,24,25,26)/t11-,16+/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	11	n/a	n/a	n/a	n/a	n/a	n/a
Institute of Cancer Research Curated by ChEMBL					Assay Description Inhibition of CHK2 by DELFIA assay				J Med Chem 54: 580-90 (2011) Article DOI: 10.1021/jm101150b BindingDB Entry DOI: 10.7270/Q2DF6RHX
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase Chk2 (Homo sapiens (Human))	BDBM50335681 ((S)-4-fluoro-2-(7-(2-methoxyethoxy)-4-(pyrrolidin-...) Show SMILES COCCOc1ccc2c(N[C@H]3CCNC3)nc(nc2c1)-c1cc(F)ccc1O |r| Show InChI InChI=1S/C21H23FN4O3/c1-28-8-9-29-15-3-4-16-18(11-15)25-21(17-10-13(22)2-5-19(17)27)26-20(16)24-14-6-7-23-12-14/h2-5,10-11,14,23,27H,6-9,12H2,1H3,(H,24,25,26)/t14-/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	11	n/a	n/a	n/a	n/a	n/a	n/a
Institute of Cancer Research Curated by ChEMBL					Assay Description Inhibition of CHK2 by DELFIA assay				J Med Chem 54: 580-90 (2011) Article DOI: 10.1021/jm101150b BindingDB Entry DOI: 10.7270/Q2DF6RHX
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase Chk2 (Homo sapiens (Human))	BDBM50335680 ((S)-2-(6,7-dimethoxy-4-(pyrrolidin-3-ylamino)quina...) Show SMILES COc1cc2nc(nc(N[C@H]3CCNC3)c2cc1OC)-c1cc(F)ccc1O |r| Show InChI InChI=1S/C20H21FN4O3/c1-27-17-8-13-15(9-18(17)28-2)24-20(14-7-11(21)3-4-16(14)26)25-19(13)23-12-5-6-22-10-12/h3-4,7-9,12,22,26H,5-6,10H2,1-2H3,(H,23,24,25)/t12-/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	12	n/a	n/a	n/a	n/a	n/a	n/a
Institute of Cancer Research Curated by ChEMBL					Assay Description Inhibition of CHK2 by DELFIA assay				J Med Chem 54: 580-90 (2011) Article DOI: 10.1021/jm101150b BindingDB Entry DOI: 10.7270/Q2DF6RHX
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase Chk2 (Homo sapiens (Human))	BDBM50335686 (2-(4-((3S,4R)-4-(2-hydroxypropan-2-yl)pyrrolidin-3...) Show SMILES CC(C)(O)[C@@H]1CNC[C@H]1Nc1nc(nc2ccccc12)-c1cc(ccc1O)-c1cn[nH]c1 |r| Show InChI InChI=1S/C24H26N6O2/c1-24(2,32)18-12-25-13-20(18)29-22-16-5-3-4-6-19(16)28-23(30-22)17-9-14(7-8-21(17)31)15-10-26-27-11-15/h3-11,18,20,25,31-32H,12-13H2,1-2H3,(H,26,27)(H,28,29,30)/t18-,20-/m1/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	14	n/a	n/a	n/a	n/a	n/a	n/a
Institute of Cancer Research Curated by ChEMBL					Assay Description Inhibition of CHK2 by DELFIA assay				J Med Chem 54: 580-90 (2011) Article DOI: 10.1021/jm101150b BindingDB Entry DOI: 10.7270/Q2DF6RHX
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase Chk2 (Homo sapiens (Human))	BDBM50335671 (4-fluoro-2-(4-((3S,4R)-4-(2-hydroxypropan-2-yl)pyr...) Show SMILES CC(C)(O)[C@@H]1CNC[C@H]1Nc1nc(nc2ccccc12)-c1cc(F)ccc1O |r| Show InChI InChI=1S/C21H23FN4O2/c1-21(2,28)15-10-23-11-17(15)25-19-13-5-3-4-6-16(13)24-20(26-19)14-9-12(22)7-8-18(14)27/h3-9,15,17,23,27-28H,10-11H2,1-2H3,(H,24,25,26)/t15-,17-/m1/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	21	n/a	n/a	n/a	n/a	n/a	n/a
Institute of Cancer Research Curated by ChEMBL					Assay Description Inhibition of CHK2 by DELFIA assay				J Med Chem 54: 580-90 (2011) Article DOI: 10.1021/jm101150b BindingDB Entry DOI: 10.7270/Q2DF6RHX
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase Chk2 (Homo sapiens (Human))	BDBM50309191 (2-Amino-N-(2-aminoethyl)-5-(2,3-dihydrothieno[3,4-...) Show SMILES NCCNC(=O)c1cc(cnc1N)-c1scc2OCCOc12 Show InChI InChI=1S/C14H16N4O3S/c15-1-2-17-14(19)9-5-8(6-18-13(9)16)12-11-10(7-22-12)20-3-4-21-11/h5-7H,1-4,15H2,(H2,16,18)(H,17,19)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	28	n/a	n/a	n/a	n/a	n/a	n/a
Institute of Cancer Research Curated by ChEMBL					Assay Description Inhibition of CHK2 by DELFIA assay				Bioorg Med Chem 18: 707-18 (2010) Article DOI: 10.1016/j.bmc.2009.11.058 BindingDB Entry DOI: 10.7270/Q26974J2
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase Chk2 (Homo sapiens (Human))	BDBM50335678 ((S)-2-(6,7-dimethoxy-4-(pyrrolidin-3-ylamino)quina...) Show SMILES COc1cc2nc(nc(N[C@H]3CCNC3)c2cc1OC)-c1ccccc1O |r| Show InChI InChI=1S/C20H22N4O3/c1-26-17-9-14-15(10-18(17)27-2)23-19(13-5-3-4-6-16(13)25)24-20(14)22-12-7-8-21-11-12/h3-6,9-10,12,21,25H,7-8,11H2,1-2H3,(H,22,23,24)/t12-/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	28	n/a	n/a	n/a	n/a	n/a	n/a
Institute of Cancer Research Curated by ChEMBL					Assay Description Inhibition of CHK2 by DELFIA assay				J Med Chem 54: 580-90 (2011) Article DOI: 10.1021/jm101150b BindingDB Entry DOI: 10.7270/Q2DF6RHX
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase Chk2 (Homo sapiens (Human))	BDBM50335673 ((S)-2-(7-methoxy-4-(pyrrolidin-3-ylamino)quinazoli...) Show SMILES COc1ccc2c(N[C@H]3CCNC3)nc(nc2c1)-c1ccccc1O |r| Show InChI InChI=1S/C19H20N4O2/c1-25-13-6-7-14-16(10-13)22-19(15-4-2-3-5-17(15)24)23-18(14)21-12-8-9-20-11-12/h2-7,10,12,20,24H,8-9,11H2,1H3,(H,21,22,23)/t12-/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	29	n/a	n/a	n/a	n/a	n/a	n/a
Institute of Cancer Research Curated by ChEMBL					Assay Description Inhibition of CHK2 by DELFIA assay				J Med Chem 54: 580-90 (2011) Article DOI: 10.1021/jm101150b BindingDB Entry DOI: 10.7270/Q2DF6RHX
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase Chk2 (Homo sapiens (Human))	BDBM50335682 ((S)-4-fluoro-2-(6-methoxy-7-(2-methoxyethoxy)-4-(p...) Show SMILES COCCOc1cc2nc(nc(N[C@H]3CCNC3)c2cc1OC)-c1cc(F)ccc1O |r| Show InChI InChI=1S/C22H25FN4O4/c1-29-7-8-31-20-11-17-15(10-19(20)30-2)21(25-14-5-6-24-12-14)27-22(26-17)16-9-13(23)3-4-18(16)28/h3-4,9-11,14,24,28H,5-8,12H2,1-2H3,(H,25,26,27)/t14-/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	30	n/a	n/a	n/a	n/a	n/a	n/a
Institute of Cancer Research Curated by ChEMBL					Assay Description Inhibition of CHK2 by DELFIA assay				J Med Chem 54: 580-90 (2011) Article DOI: 10.1021/jm101150b BindingDB Entry DOI: 10.7270/Q2DF6RHX
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase Chk2 (Homo sapiens (Human))	BDBM50335670 (4-fluoro-2-(4-((3S,4R)-4-(hydroxymethyl)pyrrolidin...) Show SMILES OC[C@@H]1CNC[C@H]1Nc1nc(nc2ccccc12)-c1cc(F)ccc1O |r| Show InChI InChI=1S/C19H19FN4O2/c20-12-5-6-17(26)14(7-12)19-22-15-4-2-1-3-13(15)18(24-19)23-16-9-21-8-11(16)10-25/h1-7,11,16,21,25-26H,8-10H2,(H,22,23,24)/t11-,16+/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	37	n/a	n/a	n/a	n/a	n/a	n/a
Institute of Cancer Research Curated by ChEMBL					Assay Description Inhibition of CHK2 by DELFIA assay				J Med Chem 54: 580-90 (2011) Article DOI: 10.1021/jm101150b BindingDB Entry DOI: 10.7270/Q2DF6RHX
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase Chk2 (Homo sapiens (Human))	BDBM50309209 (2-Amino-N-(2-aminoethyl)-5-(thiophen-3-yl)nicotina...) Show SMILES NCCNC(=O)c1cc(cnc1N)-c1ccsc1 Show InChI InChI=1S/C12H14N4OS/c13-2-3-15-12(17)10-5-9(6-16-11(10)14)8-1-4-18-7-8/h1,4-7H,2-3,13H2,(H2,14,16)(H,15,17)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	39	n/a	n/a	n/a	n/a	n/a	n/a
Institute of Cancer Research Curated by ChEMBL					Assay Description Inhibition of CHK2 in human HT29 cells				Bioorg Med Chem 18: 707-18 (2010) Article DOI: 10.1016/j.bmc.2009.11.058 BindingDB Entry DOI: 10.7270/Q26974J2
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase Chk2 (Homo sapiens (Human))	BDBM50335656 ((S)-4-fluoro-2-(4-(pyrrolidin-3-ylamino)quinazolin...) Show SMILES Oc1ccc(F)cc1-c1nc(N[C@H]2CCNC2)c2ccccc2n1 |r| Show InChI InChI=1S/C18H17FN4O/c19-11-5-6-16(24)14(9-11)18-22-15-4-2-1-3-13(15)17(23-18)21-12-7-8-20-10-12/h1-6,9,12,20,24H,7-8,10H2,(H,21,22,23)/t12-/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	60	n/a	n/a	n/a	n/a	n/a	n/a
Institute of Cancer Research Curated by ChEMBL					Assay Description Inhibition of CHK2 by DELFIA assay				J Med Chem 54: 580-90 (2011) Article DOI: 10.1021/jm101150b BindingDB Entry DOI: 10.7270/Q2DF6RHX
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase Chk2 (Homo sapiens (Human))	BDBM50335661 ((S)-4-(1H-pyrazol-4-yl)-2-(4-(pyrrolidin-3-ylamino...) Show SMILES Oc1ccc(cc1-c1nc(N[C@H]2CCNC2)c2ccccc2n1)-c1cn[nH]c1 |r| Show InChI InChI=1S/C21H20N6O/c28-19-6-5-13(14-10-23-24-11-14)9-17(19)21-26-18-4-2-1-3-16(18)20(27-21)25-15-7-8-22-12-15/h1-6,9-11,15,22,28H,7-8,12H2,(H,23,24)(H,25,26,27)/t15-/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	65	n/a	n/a	n/a	n/a	n/a	n/a
Institute of Cancer Research Curated by ChEMBL					Assay Description Inhibition of CHK2 by DELFIA assay				J Med Chem 54: 580-90 (2011) Article DOI: 10.1021/jm101150b BindingDB Entry DOI: 10.7270/Q2DF6RHX
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase Chk2 (Homo sapiens (Human))	BDBM50335675 ((S)-2-(7-(2-methoxyethoxy)-4-(pyrrolidin-3-ylamino...) Show SMILES COCCOc1ccc2c(N[C@H]3CCNC3)nc(nc2c1)-c1ccccc1O |r| Show InChI InChI=1S/C21H24N4O3/c1-27-10-11-28-15-6-7-16-18(12-15)24-21(17-4-2-3-5-19(17)26)25-20(16)23-14-8-9-22-13-14/h2-7,12,14,22,26H,8-11,13H2,1H3,(H,23,24,25)/t14-/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	70	n/a	n/a	n/a	n/a	n/a	n/a
Institute of Cancer Research Curated by ChEMBL					Assay Description Inhibition of CHK2 by DELFIA assay				J Med Chem 54: 580-90 (2011) Article DOI: 10.1021/jm101150b BindingDB Entry DOI: 10.7270/Q2DF6RHX
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase Chk2 (Homo sapiens (Human))	BDBM50335657 ((S)-4-chloro-2-(4-(pyrrolidin-3-ylamino)quinazolin...) Show SMILES Oc1ccc(Cl)cc1-c1nc(N[C@H]2CCNC2)c2ccccc2n1 |r| Show InChI InChI=1S/C18H17ClN4O/c19-11-5-6-16(24)14(9-11)18-22-15-4-2-1-3-13(15)17(23-18)21-12-7-8-20-10-12/h1-6,9,12,20,24H,7-8,10H2,(H,21,22,23)/t12-/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	70	n/a	n/a	n/a	n/a	n/a	n/a
Institute of Cancer Research Curated by ChEMBL					Assay Description Inhibition of CHK2 by DELFIA assay				J Med Chem 54: 580-90 (2011) Article DOI: 10.1021/jm101150b BindingDB Entry DOI: 10.7270/Q2DF6RHX
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase Chk2 (Homo sapiens (Human))	BDBM50335677 ((S)-2-(7-(3-hydroxypropyl)-4-(pyrrolidin-3-ylamino...) Show SMILES OCCCc1ccc2c(N[C@H]3CCNC3)nc(nc2c1)-c1ccccc1O |r| Show InChI InChI=1S/C21H24N4O2/c26-11-3-4-14-7-8-16-18(12-14)24-21(17-5-1-2-6-19(17)27)25-20(16)23-15-9-10-22-13-15/h1-2,5-8,12,15,22,26-27H,3-4,9-11,13H2,(H,23,24,25)/t15-/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	78	n/a	n/a	n/a	n/a	n/a	n/a
Institute of Cancer Research Curated by ChEMBL					Assay Description Inhibition of CHK2 by DELFIA assay				J Med Chem 54: 580-90 (2011) Article DOI: 10.1021/jm101150b BindingDB Entry DOI: 10.7270/Q2DF6RHX
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase Chk2 (Homo sapiens (Human))	BDBM50335667 (4-fluoro-2-(4-((3S,5R)-5-(hydroxymethyl)pyrrolidin...) Show SMILES OC[C@H]1C[C@@H](CN1)Nc1nc(nc2ccccc12)-c1cc(F)ccc1O |r| Show InChI InChI=1S/C19H19FN4O2/c20-11-5-6-17(26)15(7-11)19-23-16-4-2-1-3-14(16)18(24-19)22-12-8-13(10-25)21-9-12/h1-7,12-13,21,25-26H,8-10H2,(H,22,23,24)/t12-,13+/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	81	n/a	n/a	n/a	n/a	n/a	n/a
Institute of Cancer Research Curated by ChEMBL					Assay Description Inhibition of CHK2 by DELFIA assay				J Med Chem 54: 580-90 (2011) Article DOI: 10.1021/jm101150b BindingDB Entry DOI: 10.7270/Q2DF6RHX
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase Chk2 (Homo sapiens (Human))	BDBM50309182 (4-(2-Amino-5-(2,3-dihydrothieno[3,4-b][1,4]dioxin-...) Show SMILES NC(=O)c1ccc(cc1)-c1cc(cnc1N)-c1scc2OCCOc12 Show InChI InChI=1S/C18H15N3O3S/c19-17-13(10-1-3-11(4-2-10)18(20)22)7-12(8-21-17)16-15-14(9-25-16)23-5-6-24-15/h1-4,7-9H,5-6H2,(H2,19,21)(H2,20,22)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL MMDB PC cid PC sid PDB UniChem	MMDB PDB Article PubMed	n/a	n/a	92	n/a	n/a	n/a	n/a	n/a	n/a
Institute of Cancer Research Curated by ChEMBL					Assay Description Inhibition of CHK2 by DELFIA assay				Bioorg Med Chem 18: 707-18 (2010) Article DOI: 10.1016/j.bmc.2009.11.058 BindingDB Entry DOI: 10.7270/Q26974J2
					More data for this Ligand-Target Pair				3D Structure (crystal)
Serine/threonine-protein kinase Chk2 (Homo sapiens (Human))	BDBM50335658 ((S)-4-methyl-2-(4-(pyrrolidin-3-ylamino)quinazolin...) Show SMILES Cc1ccc(O)c(c1)-c1nc(N[C@H]2CCNC2)c2ccccc2n1 |r| Show InChI InChI=1S/C19H20N4O/c1-12-6-7-17(24)15(10-12)19-22-16-5-3-2-4-14(16)18(23-19)21-13-8-9-20-11-13/h2-7,10,13,20,24H,8-9,11H2,1H3,(H,21,22,23)/t13-/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	92	n/a	n/a	n/a	n/a	n/a	n/a
Institute of Cancer Research Curated by ChEMBL					Assay Description Inhibition of CHK2 by DELFIA assay				J Med Chem 54: 580-90 (2011) Article DOI: 10.1021/jm101150b BindingDB Entry DOI: 10.7270/Q2DF6RHX
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase Chk1 (Homo sapiens (Human))	BDBM50335683 (4-fluoro-2-(4-((3S,4R)-4-(2-hydroxypropan-2-yl)pyr...) Show SMILES COCCOc1cc2nc(nc(N[C@@H]3CNC[C@H]3C(C)(C)O)c2cc1OC)-c1cc(F)ccc1O |r| Show InChI InChI=1S/C25H31FN4O5/c1-25(2,32)17-12-27-13-19(17)29-23-15-10-21(34-4)22(35-8-7-33-3)11-18(15)28-24(30-23)16-9-14(26)5-6-20(16)31/h5-6,9-11,17,19,27,31-32H,7-8,12-13H2,1-4H3,(H,28,29,30)/t17-,19-/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	105	n/a	n/a	n/a	n/a	n/a	n/a
Institute of Cancer Research Curated by ChEMBL					Assay Description Inhibition of CHK1 by DELFIA assay				J Med Chem 54: 580-90 (2011) Article DOI: 10.1021/jm101150b BindingDB Entry DOI: 10.7270/Q2DF6RHX
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase Chk2 (Homo sapiens (Human))	BDBM50335679 ((S)-2-(6-methoxy-7-(2-methoxyethoxy)-4-(pyrrolidin...) Show SMILES COCCOc1cc2nc(nc(N[C@H]3CCNC3)c2cc1OC)-c1ccccc1O |r| Show InChI InChI=1S/C22H26N4O4/c1-28-9-10-30-20-12-17-16(11-19(20)29-2)22(24-14-7-8-23-13-14)26-21(25-17)15-5-3-4-6-18(15)27/h3-6,11-12,14,23,27H,7-10,13H2,1-2H3,(H,24,25,26)/t14-/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	120	n/a	n/a	n/a	n/a	n/a	n/a
Institute of Cancer Research Curated by ChEMBL					Assay Description Inhibition of CHK2 by DELFIA assay				J Med Chem 54: 580-90 (2011) Article DOI: 10.1021/jm101150b BindingDB Entry DOI: 10.7270/Q2DF6RHX
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase Chk1 (Homo sapiens (Human))	BDBM50335681 ((S)-4-fluoro-2-(7-(2-methoxyethoxy)-4-(pyrrolidin-...) Show SMILES COCCOc1ccc2c(N[C@H]3CCNC3)nc(nc2c1)-c1cc(F)ccc1O |r| Show InChI InChI=1S/C21H23FN4O3/c1-28-8-9-29-15-3-4-16-18(11-15)25-21(17-10-13(22)2-5-19(17)27)26-20(16)24-14-6-7-23-12-14/h2-5,10-11,14,23,27H,6-9,12H2,1H3,(H,24,25,26)/t14-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	140	n/a	n/a	n/a	n/a	n/a	n/a
Institute of Cancer Research Curated by ChEMBL					Assay Description Inhibition of CHK1 by DELFIA assay				J Med Chem 54: 580-90 (2011) Article DOI: 10.1021/jm101150b BindingDB Entry DOI: 10.7270/Q2DF6RHX
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase Chk2 (Homo sapiens (Human))	BDBM50335669 ((3R,4S)-ethyl 4-(2-(5-fluoro-2-hydroxyphenyl)quina...) Show SMILES CCOC(=O)[C@@H]1CNC[C@H]1Nc1nc(nc2ccccc12)-c1cc(F)ccc1O |r| Show InChI InChI=1S/C21H21FN4O3/c1-2-29-21(28)15-10-23-11-17(15)25-19-13-5-3-4-6-16(13)24-20(26-19)14-9-12(22)7-8-18(14)27/h3-9,15,17,23,27H,2,10-11H2,1H3,(H,24,25,26)/t15-,17-/m1/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	154	n/a	n/a	n/a	n/a	n/a	n/a
Institute of Cancer Research Curated by ChEMBL					Assay Description Inhibition of CHK2 by DELFIA assay				J Med Chem 54: 580-90 (2011) Article DOI: 10.1021/jm101150b BindingDB Entry DOI: 10.7270/Q2DF6RHX
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase Chk2 (Homo sapiens (Human))	BDBM50335648 ((S)-2-(4-(pyrrolidin-3-ylamino)quinazolin-2-yl)phe...) Show SMILES Oc1ccccc1-c1nc(N[C@H]2CCNC2)c2ccccc2n1 |r| Show InChI InChI=1S/C18H18N4O/c23-16-8-4-2-6-14(16)18-21-15-7-3-1-5-13(15)17(22-18)20-12-9-10-19-11-12/h1-8,12,19,23H,9-11H2,(H,20,21,22)/t12-/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid PDB UniChem Similars	PDB Article PubMed	n/a	n/a	160	n/a	n/a	n/a	n/a	n/a	n/a
Institute of Cancer Research Curated by ChEMBL					Assay Description Inhibition of CHK2 by DELFIA assay				J Med Chem 54: 580-90 (2011) Article DOI: 10.1021/jm101150b BindingDB Entry DOI: 10.7270/Q2DF6RHX
					More data for this Ligand-Target Pair				3D Structure (crystal)
Serine/threonine-protein kinase Chk2 (Homo sapiens (Human))	BDBM50335651 ((R)-2-(4-(piperidin-3-ylamino)quinazolin-2-yl)phen...) Show SMILES Oc1ccccc1-c1nc(N[C@@H]2CCCNC2)c2ccccc2n1 |r| Show InChI InChI=1S/C19H20N4O/c24-17-10-4-2-8-15(17)19-22-16-9-3-1-7-14(16)18(23-19)21-13-6-5-11-20-12-13/h1-4,7-10,13,20,24H,5-6,11-12H2,(H,21,22,23)/t13-/m1/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	180	n/a	n/a	n/a	n/a	n/a	n/a
Institute of Cancer Research Curated by ChEMBL					Assay Description Inhibition of CHK2 by DELFIA assay				J Med Chem 54: 580-90 (2011) Article DOI: 10.1021/jm101150b BindingDB Entry DOI: 10.7270/Q2DF6RHX
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase Chk2 (Homo sapiens (Human))	BDBM50335665 ((2R,4S)-4-(2-(2-hydroxyphenyl)quinazolin-4-ylamino...) Show SMILES CN(C)C(=O)[C@H]1C[C@@H](CN1)Nc1nc(nc2ccccc12)-c1ccccc1O |r| Show InChI InChI=1S/C21H23N5O2/c1-26(2)21(28)17-11-13(12-22-17)23-19-14-7-3-5-9-16(14)24-20(25-19)15-8-4-6-10-18(15)27/h3-10,13,17,22,27H,11-12H2,1-2H3,(H,23,24,25)/t13-,17+/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	181	n/a	n/a	n/a	n/a	n/a	n/a
Institute of Cancer Research Curated by ChEMBL					Assay Description Inhibition of CHK2 by DELFIA assay				J Med Chem 54: 580-90 (2011) Article DOI: 10.1021/jm101150b BindingDB Entry DOI: 10.7270/Q2DF6RHX
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase Chk1 (Homo sapiens (Human))	BDBM50335684 (4-FLUORO-2-(4-{[(3S,4R)-4-(1-HYDROXY-1-METHYLETHYL...) Show SMILES COc1cc2nc(nc(N[C@@H]3CNC[C@H]3C(C)(C)O)c2cc1OC)-c1cc(F)ccc1O |r| Show InChI InChI=1S/C23H27FN4O4/c1-23(2,30)15-10-25-11-17(15)27-21-13-8-19(31-3)20(32-4)9-16(13)26-22(28-21)14-7-12(24)5-6-18(14)29/h5-9,15,17,25,29-30H,10-11H2,1-4H3,(H,26,27,28)/t15-,17-/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE MMDB PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	190	n/a	n/a	n/a	n/a	n/a	n/a
Institute of Cancer Research Curated by ChEMBL					Assay Description Inhibition of CHK1 by DELFIA assay				J Med Chem 54: 580-90 (2011) Article DOI: 10.1021/jm101150b BindingDB Entry DOI: 10.7270/Q2DF6RHX
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase Chk1 (Homo sapiens (Human))	BDBM50335680 ((S)-2-(6,7-dimethoxy-4-(pyrrolidin-3-ylamino)quina...) Show SMILES COc1cc2nc(nc(N[C@H]3CCNC3)c2cc1OC)-c1cc(F)ccc1O |r| Show InChI InChI=1S/C20H21FN4O3/c1-27-17-8-13-15(9-18(17)28-2)24-20(14-7-11(21)3-4-16(14)26)25-19(13)23-12-5-6-22-10-12/h3-4,7-9,12,22,26H,5-6,10H2,1-2H3,(H,23,24,25)/t12-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	200	n/a	n/a	n/a	n/a	n/a	n/a
Institute of Cancer Research Curated by ChEMBL					Assay Description Inhibition of CHK1 by DELFIA assay				J Med Chem 54: 580-90 (2011) Article DOI: 10.1021/jm101150b BindingDB Entry DOI: 10.7270/Q2DF6RHX
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase Chk2 (Homo sapiens (Human))	BDBM50335672 ((S)-2-(6-methoxy-4-(pyrrolidin-3-ylamino)quinazoli...) Show SMILES COc1ccc2nc(nc(N[C@H]3CCNC3)c2c1)-c1ccccc1O |r| Show InChI InChI=1S/C19H20N4O2/c1-25-13-6-7-16-15(10-13)19(21-12-8-9-20-11-12)23-18(22-16)14-4-2-3-5-17(14)24/h2-7,10,12,20,24H,8-9,11H2,1H3,(H,21,22,23)/t12-/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	200	n/a	n/a	n/a	n/a	n/a	n/a
Institute of Cancer Research Curated by ChEMBL					Assay Description Inhibition of CHK2 by DELFIA assay				J Med Chem 54: 580-90 (2011) Article DOI: 10.1021/jm101150b BindingDB Entry DOI: 10.7270/Q2DF6RHX
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase Chk2 (Homo sapiens (Human))	BDBM50335660 ((S)-2-(4-(pyrrolidin-3-ylamino)quinazolin-2-yl)-4-...) Show SMILES Oc1ccc(cc1-c1nc(N[C@H]2CCNC2)c2ccccc2n1)C(F)(F)F |r| Show InChI InChI=1S/C19H17F3N4O/c20-19(21,22)11-5-6-16(27)14(9-11)18-25-15-4-2-1-3-13(15)17(26-18)24-12-7-8-23-10-12/h1-6,9,12,23,27H,7-8,10H2,(H,24,25,26)/t12-/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	201	n/a	n/a	n/a	n/a	n/a	n/a
Institute of Cancer Research Curated by ChEMBL					Assay Description Inhibition of CHK2 by DELFIA assay				J Med Chem 54: 580-90 (2011) Article DOI: 10.1021/jm101150b BindingDB Entry DOI: 10.7270/Q2DF6RHX
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase Chk2 (Homo sapiens (Human))	BDBM50309178 (4-(2-Amino-5-(benzo[d][1,3]dioxol-4-yl)pyridin-3-y...) Show SMILES NC(=O)c1ccc(cc1)-c1cc(cnc1N)-c1cccc2OCOc12 Show InChI InChI=1S/C19H15N3O3/c20-18-15(11-4-6-12(7-5-11)19(21)23)8-13(9-22-18)14-2-1-3-16-17(14)25-10-24-16/h1-9H,10H2,(H2,20,22)(H2,21,23)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL MMDB PC cid PC sid PDB UniChem Similars	MMDB PDB Article PubMed	n/a	n/a	210	n/a	n/a	n/a	n/a	n/a	n/a
Institute of Cancer Research Curated by ChEMBL					Assay Description Inhibition of CHK2 by DELFIA assay				Bioorg Med Chem 18: 707-18 (2010) Article DOI: 10.1016/j.bmc.2009.11.058 BindingDB Entry DOI: 10.7270/Q26974J2
					More data for this Ligand-Target Pair				3D Structure (crystal)
Serine/threonine-protein kinase Chk1 (Homo sapiens (Human))	BDBM50335685 (4-fluoro-2-(4-((3S,4R)-4-(hydroxymethyl)pyrrolidin...) Show SMILES COc1cc2nc(nc(N[C@@H]3CNC[C@H]3CO)c2cc1OC)-c1cc(F)ccc1O |r| Show InChI InChI=1S/C21H23FN4O4/c1-29-18-6-13-15(7-19(18)30-2)24-21(14-5-12(22)3-4-17(14)28)26-20(13)25-16-9-23-8-11(16)10-27/h3-7,11,16,23,27-28H,8-10H2,1-2H3,(H,24,25,26)/t11-,16+/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	230	n/a	n/a	n/a	n/a	n/a	n/a
Institute of Cancer Research Curated by ChEMBL					Assay Description Inhibition of CHK1 by DELFIA assay				J Med Chem 54: 580-90 (2011) Article DOI: 10.1021/jm101150b BindingDB Entry DOI: 10.7270/Q2DF6RHX
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase Chk2 (Homo sapiens (Human))	BDBM50335654 (2-(4-(azepan-3-ylamino)quinazolin-2-yl)phenol | CH...) Show SMILES Oc1ccccc1-c1nc(NC2CCCCNC2)c2ccccc2n1 Show InChI InChI=1S/C20H22N4O/c25-18-11-4-2-9-16(18)20-23-17-10-3-1-8-15(17)19(24-20)22-14-7-5-6-12-21-13-14/h1-4,8-11,14,21,25H,5-7,12-13H2,(H,22,23,24)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	250	n/a	n/a	n/a	n/a	n/a	n/a
Institute of Cancer Research Curated by ChEMBL					Assay Description Inhibition of CHK2 by DELFIA assay				J Med Chem 54: 580-90 (2011) Article DOI: 10.1021/jm101150b BindingDB Entry DOI: 10.7270/Q2DF6RHX
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase Chk1 (Homo sapiens (Human))	BDBM50335682 ((S)-4-fluoro-2-(6-methoxy-7-(2-methoxyethoxy)-4-(p...) Show SMILES COCCOc1cc2nc(nc(N[C@H]3CCNC3)c2cc1OC)-c1cc(F)ccc1O |r| Show InChI InChI=1S/C22H25FN4O4/c1-29-7-8-31-20-11-17-15(10-19(20)30-2)21(25-14-5-6-24-12-14)27-22(26-17)16-9-13(23)3-4-18(16)28/h3-4,9-11,14,24,28H,5-8,12H2,1-2H3,(H,25,26,27)/t14-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	260	n/a	n/a	n/a	n/a	n/a	n/a
Institute of Cancer Research Curated by ChEMBL					Assay Description Inhibition of CHK1 by DELFIA assay				J Med Chem 54: 580-90 (2011) Article DOI: 10.1021/jm101150b BindingDB Entry DOI: 10.7270/Q2DF6RHX
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase Chk2 (Homo sapiens (Human))	BDBM50309194 (4-(2-Amino-5-(3,4-dimethoxyphenyl)pyridin-3-yl)ben...) Show SMILES COc1ccc(cc1OC)-c1cnc(N)c(c1)-c1ccc(cc1)C(N)=O Show InChI InChI=1S/C20H19N3O3/c1-25-17-8-7-14(10-18(17)26-2)15-9-16(19(21)23-11-15)12-3-5-13(6-4-12)20(22)24/h3-11H,1-2H3,(H2,21,23)(H2,22,24)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	270	n/a	n/a	n/a	n/a	n/a	n/a
Institute of Cancer Research Curated by ChEMBL					Assay Description Inhibition of CHK2 in human HT29 cells				Bioorg Med Chem 18: 707-18 (2010) Article DOI: 10.1016/j.bmc.2009.11.058 BindingDB Entry DOI: 10.7270/Q26974J2
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase Chk2 (Homo sapiens (Human))	BDBM50335674 ((S)-2-(6-(2-methoxyethoxy)-4-(pyrrolidin-3-ylamino...) Show SMILES COCCOc1ccc2nc(nc(N[C@H]3CCNC3)c2c1)-c1ccccc1O |r| Show InChI InChI=1S/C21H24N4O3/c1-27-10-11-28-15-6-7-18-17(12-15)21(23-14-8-9-22-13-14)25-20(24-18)16-4-2-3-5-19(16)26/h2-7,12,14,22,26H,8-11,13H2,1H3,(H,23,24,25)/t14-/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	280	n/a	n/a	n/a	n/a	n/a	n/a
Institute of Cancer Research Curated by ChEMBL					Assay Description Inhibition of CHK2 by DELFIA assay				J Med Chem 54: 580-90 (2011) Article DOI: 10.1021/jm101150b BindingDB Entry DOI: 10.7270/Q2DF6RHX
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase Chk2 (Homo sapiens (Human))	BDBM50309206 (4-(2-Amino-5-(4-hydroxy-3-methoxyphenyl)pyridin-3-...) Show SMILES COc1cc(ccc1O)-c1cnc(N)c(c1)-c1ccc(cc1)C(N)=O Show InChI InChI=1S/C19H17N3O3/c1-25-17-9-13(6-7-16(17)23)14-8-15(18(20)22-10-14)11-2-4-12(5-3-11)19(21)24/h2-10,23H,1H3,(H2,20,22)(H2,21,24)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL MMDB PC cid PC sid PDB UniChem Similars	MMDB PDB Article PubMed	n/a	n/a	310	n/a	n/a	n/a	n/a	n/a	n/a
Institute of Cancer Research Curated by ChEMBL					Assay Description Inhibition of CHK2 in human HT29 cells				Bioorg Med Chem 18: 707-18 (2010) Article DOI: 10.1016/j.bmc.2009.11.058 BindingDB Entry DOI: 10.7270/Q26974J2
					More data for this Ligand-Target Pair				3D Structure (crystal)
Serine/threonine-protein kinase Chk1 (Homo sapiens (Human))	BDBM50335679 ((S)-2-(6-methoxy-7-(2-methoxyethoxy)-4-(pyrrolidin...) Show SMILES COCCOc1cc2nc(nc(N[C@H]3CCNC3)c2cc1OC)-c1ccccc1O |r| Show InChI InChI=1S/C22H26N4O4/c1-28-9-10-30-20-12-17-16(11-19(20)29-2)22(24-14-7-8-23-13-14)26-21(25-17)15-5-3-4-6-18(15)27/h3-6,11-12,14,23,27H,7-10,13H2,1-2H3,(H,24,25,26)/t14-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	330	n/a	n/a	n/a	n/a	n/a	n/a
Institute of Cancer Research Curated by ChEMBL					Assay Description Inhibition of CHK1 by DELFIA assay				J Med Chem 54: 580-90 (2011) Article DOI: 10.1021/jm101150b BindingDB Entry DOI: 10.7270/Q2DF6RHX
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase Chk2 (Homo sapiens (Human))	BDBM50309184 (4-(2-Amino-5-(thiophen-2-yl)pyridin-3-yl)benzamide...) Show SMILES NC(=O)c1ccc(cc1)-c1cc(cnc1N)-c1cccs1 Show InChI InChI=1S/C16H13N3OS/c17-15-13(10-3-5-11(6-4-10)16(18)20)8-12(9-19-15)14-2-1-7-21-14/h1-9H,(H2,17,19)(H2,18,20)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	350	n/a	n/a	n/a	n/a	n/a	n/a
Institute of Cancer Research Curated by ChEMBL					Assay Description Inhibition of CHK2 in human HT29 cells				Bioorg Med Chem 18: 707-18 (2010) Article DOI: 10.1016/j.bmc.2009.11.058 BindingDB Entry DOI: 10.7270/Q26974J2
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase Chk2 (Homo sapiens (Human))	BDBM50309187 (2-Amino-N-(3-amino-3-oxopropyl)-5-(thiophen-3-yl)n...) Show SMILES NC(=O)CCNC(=O)c1cc(cnc1N)-c1ccsc1 Show InChI InChI=1S/C13H14N4O2S/c14-11(18)1-3-16-13(19)10-5-9(6-17-12(10)15)8-2-4-20-7-8/h2,4-7H,1,3H2,(H2,14,18)(H2,15,17)(H,16,19)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	410	n/a	n/a	n/a	n/a	n/a	n/a
Institute of Cancer Research Curated by ChEMBL					Assay Description Inhibition of CHK2 in human HT29 cells				Bioorg Med Chem 18: 707-18 (2010) Article DOI: 10.1016/j.bmc.2009.11.058 BindingDB Entry DOI: 10.7270/Q26974J2
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase Chk2 (Homo sapiens (Human))	BDBM50309186 (4-(2-Amino-5-(3-(2-methoxyethoxy)phenyl)pyridin-3-...) Show SMILES COCCOc1cccc(c1)-c1cnc(N)c(c1)-c1ccc(cc1)C(N)=O Show InChI InChI=1S/C21H21N3O3/c1-26-9-10-27-18-4-2-3-16(11-18)17-12-19(20(22)24-13-17)14-5-7-15(8-6-14)21(23)25/h2-8,11-13H,9-10H2,1H3,(H2,22,24)(H2,23,25)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	420	n/a	n/a	n/a	n/a	n/a	n/a
Institute of Cancer Research Curated by ChEMBL					Assay Description Inhibition of CHK2 in human HT29 cells				Bioorg Med Chem 18: 707-18 (2010) Article DOI: 10.1016/j.bmc.2009.11.058 BindingDB Entry DOI: 10.7270/Q26974J2
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase Chk2 (Homo sapiens (Human))	BDBM50335666 (4-fluoro-2-(4-((3S,5R)-5-(2-hydroxypropan-2-yl)pyr...) Show SMILES CC(C)(O)[C@H]1C[C@@H](CN1)Nc1nc(nc2ccccc12)-c1cc(F)ccc1O |r| Show InChI InChI=1S/C21H23FN4O2/c1-21(2,28)18-10-13(11-23-18)24-19-14-5-3-4-6-16(14)25-20(26-19)15-9-12(22)7-8-17(15)27/h3-9,13,18,23,27-28H,10-11H2,1-2H3,(H,24,25,26)/t13-,18+/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	460	n/a	n/a	n/a	n/a	n/a	n/a
Institute of Cancer Research Curated by ChEMBL					Assay Description Inhibition of CHK2 by DELFIA assay				J Med Chem 54: 580-90 (2011) Article DOI: 10.1021/jm101150b BindingDB Entry DOI: 10.7270/Q2DF6RHX
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase Chk2 (Homo sapiens (Human))	BDBM50335653 ((S)-2-(4-(methyl(pyrrolidin-3-yl)amino)quinazolin-...) Show SMILES CN([C@H]1CCNC1)c1nc(nc2ccccc12)-c1ccccc1O |r| Show InChI InChI=1S/C19H20N4O/c1-23(13-10-11-20-12-13)19-14-6-2-4-8-16(14)21-18(22-19)15-7-3-5-9-17(15)24/h2-9,13,20,24H,10-12H2,1H3/t13-/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	500	n/a	n/a	n/a	n/a	n/a	n/a
Institute of Cancer Research Curated by ChEMBL					Assay Description Inhibition of CHK2 by DELFIA assay				J Med Chem 54: 580-90 (2011) Article DOI: 10.1021/jm101150b BindingDB Entry DOI: 10.7270/Q2DF6RHX
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase Chk2 (Homo sapiens (Human))	BDBM50335655 (2-(4-(azepan-4-ylamino)quinazolin-2-yl)phenol | CH...) Show SMILES Oc1ccccc1-c1nc(NC2CCCNCC2)c2ccccc2n1 Show InChI InChI=1S/C20H22N4O/c25-18-10-4-2-8-16(18)20-23-17-9-3-1-7-15(17)19(24-20)22-14-6-5-12-21-13-11-14/h1-4,7-10,14,21,25H,5-6,11-13H2,(H,22,23,24)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	510	n/a	n/a	n/a	n/a	n/a	n/a
Institute of Cancer Research Curated by ChEMBL					Assay Description Inhibition of CHK2 by DELFIA assay				J Med Chem 54: 580-90 (2011) Article DOI: 10.1021/jm101150b BindingDB Entry DOI: 10.7270/Q2DF6RHX
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase Chk2 (Homo sapiens (Human))	BDBM50335676 ((S)-2-(6-(3-hydroxypropyl)-4-(pyrrolidin-3-ylamino...) Show SMILES OCCCc1ccc2nc(nc(N[C@H]3CCNC3)c2c1)-c1ccccc1O |r| Show InChI InChI=1S/C21H24N4O2/c26-11-3-4-14-7-8-18-17(12-14)21(23-15-9-10-22-13-15)25-20(24-18)16-5-1-2-6-19(16)27/h1-2,5-8,12,15,22,26-27H,3-4,9-11,13H2,(H,23,24,25)/t15-/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	600	n/a	n/a	n/a	n/a	n/a	n/a
Institute of Cancer Research Curated by ChEMBL					Assay Description Inhibition of CHK2 by DELFIA assay				J Med Chem 54: 580-90 (2011) Article DOI: 10.1021/jm101150b BindingDB Entry DOI: 10.7270/Q2DF6RHX
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase Chk2 (Homo sapiens (Human))	BDBM50309210 (4-(2-Amino-5-(3-methoxyphenyl)pyridin-3-yl)benzami...) Show SMILES COc1cccc(c1)-c1cnc(N)c(c1)-c1ccc(cc1)C(N)=O Show InChI InChI=1S/C19H17N3O2/c1-24-16-4-2-3-14(9-16)15-10-17(18(20)22-11-15)12-5-7-13(8-6-12)19(21)23/h2-11H,1H3,(H2,20,22)(H2,21,23)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	600	n/a	n/a	n/a	n/a	n/a	n/a
Institute of Cancer Research Curated by ChEMBL					Assay Description Inhibition of CHK2 in human HT29 cells				Bioorg Med Chem 18: 707-18 (2010) Article DOI: 10.1016/j.bmc.2009.11.058 BindingDB Entry DOI: 10.7270/Q26974J2
					More data for this Ligand-Target Pair

Displayed 1 to 50 (of 133 total )  |  Next  |  Last  >>

Jump to: