Compile Data Set for Download or QSAR

Found 69 hits with Last Name = 'andrews' and Initial = 'jm'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Prothrombin (Homo sapiens (Human))	BDBM50010247 (CHEMBL3247184) Show SMILES NC(=N)c1cccc(c1)C(O)=O Show InChI InChI=1S/C8H8N2O2/c9-7(10)5-2-1-3-6(4-5)8(11)12/h1-4H,(H3,9,10)(H,11,12)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem	PubMed	3.98E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Competitive inhibition of esterase activity of human thrombin assessed as decrease in p-nitrophenol production using Nalpha-Z-L-Lys-ONp as substrate ...				J Med Chem 21: 1202-7 (1979) BindingDB Entry DOI: 10.7270/Q2ST7RCQ
					More data for this Ligand-Target Pair
Plasminogen (Homo sapiens (Human))	BDBM50010252 (CHEMBL3247187) Show SMILES NC(=N)c1cccc(c1)-c1ccccc1 Show InChI InChI=1S/C13H12N2/c14-13(15)12-8-4-7-11(9-12)10-5-2-1-3-6-10/h1-9H,(H3,14,15)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	PubMed	4.00E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Competitive inhibition of esterase activity of human plasmin assessed as assessed as decrease in p-nitrophenol production using N-Z-L-Tyr-ONp as subs...				J Med Chem 21: 1202-7 (1979) BindingDB Entry DOI: 10.7270/Q2ST7RCQ
					More data for this Ligand-Target Pair
Prothrombin (Homo sapiens (Human))	BDBM50010249 (CHEMBL3247185) Show SMILES NC(=N)c1cccc(Cc2ccccc2)c1 Show InChI InChI=1S/C14H14N2/c15-14(16)13-8-4-7-12(10-13)9-11-5-2-1-3-6-11/h1-8,10H,9H2,(H3,15,16)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	PubMed	6.30E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Competitive inhibition of esterase activity of human thrombin assessed as decrease in p-nitrophenol production using Nalpha-Z-L-Lys-ONp as substrate ...				J Med Chem 21: 1202-7 (1979) BindingDB Entry DOI: 10.7270/Q2ST7RCQ
					More data for this Ligand-Target Pair
Complement C1s subcomponent (Homo sapiens (Human))	BDBM50010258 (CHEMBL3247193) Show SMILES NC(=N)c1cccc(OCCCOc2ccccc2)c1 Show InChI InChI=1S/C16H18N2O2/c17-16(18)13-6-4-9-15(12-13)20-11-5-10-19-14-7-2-1-3-8-14/h1-4,6-9,12H,5,10-11H2,(H3,17,18)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Competitive inhibition of esterase activity of human activated C1s subunit of first complement component assessed as decrease in p-nitrophenol produc...				J Med Chem 21: 1202-7 (1979) BindingDB Entry DOI: 10.7270/Q2ST7RCQ
					More data for this Ligand-Target Pair
Plasminogen (Homo sapiens (Human))	BDBM8527 (n,n-dimethyl, m-aminobenzamidine) Show SMILES CN(C)c1cccc(c1)C(N)=N Show InChI InChI=1S/C9H13N3/c1-12(2)8-5-3-4-7(6-8)9(10)11/h3-6H,1-2H3,(H3,10,11)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem	PubMed	1.25E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Competitive inhibition of esterase activity of human plasmin assessed as assessed as decrease in p-nitrophenol production using N-Z-L-Tyr-ONp as subs...				J Med Chem 21: 1202-7 (1979) BindingDB Entry DOI: 10.7270/Q2ST7RCQ
					More data for this Ligand-Target Pair
Complement C1s subcomponent (Homo sapiens (Human))	BDBM50010258 (CHEMBL3247193) Show SMILES NC(=N)c1cccc(OCCCOc2ccccc2)c1 Show InChI InChI=1S/C16H18N2O2/c17-16(18)13-6-4-9-15(12-13)20-11-5-10-19-14-7-2-1-3-8-14/h1-4,6-9,12H,5,10-11H2,(H3,17,18)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	1.25E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Competitive inhibition of esterase activity of human activated C1s subunit of first complement component assessed as decrease in p-nitrophenol produc...				J Med Chem 21: 1202-7 (1979) BindingDB Entry DOI: 10.7270/Q2ST7RCQ
					More data for this Ligand-Target Pair
Prothrombin (Homo sapiens (Human))	BDBM50010258 (CHEMBL3247193) Show SMILES NC(=N)c1cccc(OCCCOc2ccccc2)c1 Show InChI InChI=1S/C16H18N2O2/c17-16(18)13-6-4-9-15(12-13)20-11-5-10-19-14-7-2-1-3-8-14/h1-4,6-9,12H,5,10-11H2,(H3,17,18)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	1.58E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Competitive inhibition of esterase activity of human activated C1s subunit of first complement component assessed as decrease in p-nitrophenol produc...				J Med Chem 21: 1202-7 (1979) BindingDB Entry DOI: 10.7270/Q2ST7RCQ
					More data for this Ligand-Target Pair
Prothrombin (Homo sapiens (Human))	BDBM50010253 (CHEMBL3247189) Show SMILES COc1cccc(c1)C(N)=N Show InChI InChI=1S/C8H10N2O/c1-11-7-4-2-3-6(5-7)8(9)10/h2-5H,1H3,(H3,9,10)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem	PubMed	1.58E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Competitive inhibition of esterase activity of human plasmin assessed as assessed as decrease in p-nitrophenol production using N-Z-L-Tyr-ONp as subs...				J Med Chem 21: 1202-7 (1979) BindingDB Entry DOI: 10.7270/Q2ST7RCQ
					More data for this Ligand-Target Pair
Complement C1s subcomponent (Homo sapiens (Human))	BDBM8527 (n,n-dimethyl, m-aminobenzamidine) Show SMILES CN(C)c1cccc(c1)C(N)=N Show InChI InChI=1S/C9H13N3/c1-12(2)8-5-3-4-7(6-8)9(10)11/h3-6H,1-2H3,(H3,10,11)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem	PubMed	1.99E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Competitive inhibition of esterase activity of human plasmin assessed as assessed as decrease in p-nitrophenol production using N-Z-L-Tyr-ONp as subs...				J Med Chem 21: 1202-7 (1979) BindingDB Entry DOI: 10.7270/Q2ST7RCQ
					More data for this Ligand-Target Pair
Plasminogen (Homo sapiens (Human))	BDBM50010258 (CHEMBL3247193) Show SMILES NC(=N)c1cccc(OCCCOc2ccccc2)c1 Show InChI InChI=1S/C16H18N2O2/c17-16(18)13-6-4-9-15(12-13)20-11-5-10-19-14-7-2-1-3-8-14/h1-4,6-9,12H,5,10-11H2,(H3,17,18)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	2.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Competitive inhibition of esterase activity of human activated C1s subunit of first complement component assessed as decrease in p-nitrophenol produc...				J Med Chem 21: 1202-7 (1979) BindingDB Entry DOI: 10.7270/Q2ST7RCQ
					More data for this Ligand-Target Pair
Prothrombin (Homo sapiens (Human))	BDBM50010287 (CHEMBL3138844) Show SMILES COc1ccc(cc1)C(N)=N Show InChI InChI=1S/C8H10N2O/c1-11-7-4-2-6(3-5-7)8(9)10/h2-5H,1H3,(H3,9,10)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid PDB UniChem Similars	PubMed	3.16E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Competitive inhibition of esterase activity of human activated C1s subunit of first complement component assessed as decrease in p-nitrophenol produc...				J Med Chem 21: 1202-7 (1979) BindingDB Entry DOI: 10.7270/Q2ST7RCQ
					More data for this Ligand-Target Pair
Prothrombin (Homo sapiens (Human))	BDBM50010244 (CHEMBL3247181) Show SMILES NC(=N)c1cccc(CO)c1 Show InChI InChI=1S/C8H10N2O/c9-8(10)7-3-1-2-6(4-7)5-11/h1-4,11H,5H2,(H3,9,10)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem	PubMed	3.20E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Competitive inhibition of esterase activity of human thrombin assessed as decrease in p-nitrophenol production using Nalpha-Z-L-Lys-ONp as substrate ...				J Med Chem 21: 1202-7 (1979) BindingDB Entry DOI: 10.7270/Q2ST7RCQ
					More data for this Ligand-Target Pair
Prothrombin (Homo sapiens (Human))	BDBM50010245 (CHEMBL3247182) Show SMILES Cc1ccccc1C(N)=N Show InChI InChI=1S/C8H10N2/c1-6-4-2-3-5-7(6)8(9)10/h2-5H,1H3,(H3,9,10)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Similars	PubMed	3.98E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Competitive inhibition of esterase activity of human thrombin assessed as decrease in p-nitrophenol production using Nalpha-Z-L-Lys-ONp as substrate ...				J Med Chem 21: 1202-7 (1979) BindingDB Entry DOI: 10.7270/Q2ST7RCQ
					More data for this Ligand-Target Pair
Complement C1s subcomponent (Homo sapiens (Human))	BDBM50010256 (CHEMBL3247192) Show SMILES Cc1cc(C)cc(c1)C(N)=N Show InChI InChI=1S/C9H12N2/c1-6-3-7(2)5-8(4-6)9(10)11/h3-5H,1-2H3,(H3,10,11)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Similars	PubMed	7.90E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Competitive inhibition of esterase activity of human activated C1s subunit of first complement component assessed as decrease in p-nitrophenol produc...				J Med Chem 21: 1202-7 (1979) BindingDB Entry DOI: 10.7270/Q2ST7RCQ
					More data for this Ligand-Target Pair
Complement C1s subcomponent (Homo sapiens (Human))	BDBM50010257 (CHEMBL1231012) Show SMILES NC(=N)c1ccc(CC(=O)C(O)=O)cc1 Show InChI InChI=1S/C10H10N2O3/c11-9(12)7-3-1-6(2-4-7)5-8(13)10(14)15/h1-4H,5H2,(H3,11,12)(H,14,15)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL DrugBank KEGG PC cid PC sid UniChem Similars	PubMed	7.94E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Competitive inhibition of esterase activity of human activated C1s subunit of first complement component assessed as decrease in p-nitrophenol produc...				J Med Chem 21: 1202-7 (1979) BindingDB Entry DOI: 10.7270/Q2ST7RCQ
					More data for this Ligand-Target Pair
Plasminogen (Homo sapiens (Human))	BDBM50010304 (CHEMBL3247195) Show SMILES NC(=N)c1cccc(c1)C(=N)Nc1cccc2ccccc12 Show InChI InChI=1S/C18H16N4/c19-17(20)13-7-3-8-14(11-13)18(21)22-16-10-4-6-12-5-1-2-9-15(12)16/h1-11H,(H3,19,20)(H2,21,22)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	PubMed	7.94E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Competitive inhibition of esterase activity of human thrombin assessed as decrease in p-nitrophenol production using Nalpha-Z-L-Tyr-ONp as substrate ...				J Med Chem 21: 1202-7 (1979) BindingDB Entry DOI: 10.7270/Q2ST7RCQ
					More data for this Ligand-Target Pair
Prothrombin (Homo sapiens (Human))	BDBM50010249 (CHEMBL3247185) Show SMILES NC(=N)c1cccc(Cc2ccccc2)c1 Show InChI InChI=1S/C14H14N2/c15-14(16)13-8-4-7-12(10-13)9-11-5-2-1-3-6-11/h1-8,10H,9H2,(H3,15,16)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	PubMed	9.99E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Competitive inhibition of esterase activity of human thrombin assessed as decrease in p-nitrophenol production using Nalpha-Z-L-Lys-ONp as substrate ...				J Med Chem 21: 1202-7 (1979) BindingDB Entry DOI: 10.7270/Q2ST7RCQ
					More data for this Ligand-Target Pair
Plasminogen (Homo sapiens (Human))	BDBM50010257 (CHEMBL1231012) Show SMILES NC(=N)c1ccc(CC(=O)C(O)=O)cc1 Show InChI InChI=1S/C10H10N2O3/c11-9(12)7-3-1-6(2-4-7)5-8(13)10(14)15/h1-4H,5H2,(H3,11,12)(H,14,15)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL DrugBank KEGG PC cid PC sid UniChem Similars	PubMed	9.99E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Competitive inhibition of esterase activity of human activated C1s subunit of first complement component assessed as decrease in p-nitrophenol produc...				J Med Chem 21: 1202-7 (1979) BindingDB Entry DOI: 10.7270/Q2ST7RCQ
					More data for this Ligand-Target Pair
Complement C1s subcomponent (Homo sapiens (Human))	BDBM50010279 (CHEMBL3138975) Show SMILES CCOc1ccc(cc1)C(N)=N Show InChI InChI=1S/C9H12N2O/c1-2-12-8-5-3-7(4-6-8)9(10)11/h3-6H,2H2,1H3,(H3,10,11)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE MMDB PC cid PC sid UniChem Patents Similars	PubMed	1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Competitive inhibition of esterase activity of human activated C1s subunit of first complement component assessed as decrease in p-nitrophenol produc...				J Med Chem 21: 1202-7 (1979) BindingDB Entry DOI: 10.7270/Q2ST7RCQ
					More data for this Ligand-Target Pair
Plasminogen (Homo sapiens (Human))	BDBM50010250 (CHEMBL3247186) Show SMILES Cl.NC(=N)c1cccc(N)c1 Show InChI InChI=1S/C7H9N3.ClH/c8-6-3-1-2-5(4-6)7(9)10;/h1-4H,8H2,(H3,9,10);1H	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem	PubMed	1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Competitive inhibition of esterase activity of human plasmin assessed as assessed as decrease in p-nitrophenol production using N-Z-L-Tyr-ONp as subs...				J Med Chem 21: 1202-7 (1979) BindingDB Entry DOI: 10.7270/Q2ST7RCQ
					More data for this Ligand-Target Pair
Complement C1s subcomponent (Homo sapiens (Human))	BDBM50010287 (CHEMBL3138844) Show SMILES COc1ccc(cc1)C(N)=N Show InChI InChI=1S/C8H10N2O/c1-11-7-4-2-6(3-5-7)8(9)10/h2-5H,1H3,(H3,9,10)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid PDB UniChem Similars	PubMed	1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Competitive inhibition of esterase activity of human activated C1s subunit of first complement component assessed as decrease in p-nitrophenol produc...				J Med Chem 21: 1202-7 (1979) BindingDB Entry DOI: 10.7270/Q2ST7RCQ
					More data for this Ligand-Target Pair
Prothrombin (Homo sapiens (Human))	BDBM50010257 (CHEMBL1231012) Show SMILES NC(=N)c1ccc(CC(=O)C(O)=O)cc1 Show InChI InChI=1S/C10H10N2O3/c11-9(12)7-3-1-6(2-4-7)5-8(13)10(14)15/h1-4H,5H2,(H3,11,12)(H,14,15)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL DrugBank KEGG PC cid PC sid UniChem Similars	PubMed	1.25E+5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Competitive inhibition of esterase activity of human activated C1s subunit of first complement component assessed as decrease in p-nitrophenol produc...				J Med Chem 21: 1202-7 (1979) BindingDB Entry DOI: 10.7270/Q2ST7RCQ
					More data for this Ligand-Target Pair
Plasminogen (Homo sapiens (Human))	BDBM50010250 (CHEMBL3247186) Show SMILES Cl.NC(=N)c1cccc(N)c1 Show InChI InChI=1S/C7H9N3.ClH/c8-6-3-1-2-5(4-6)7(9)10;/h1-4H,8H2,(H3,9,10);1H	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem	PubMed	1.25E+5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Competitive inhibition of esterase activity of human plasmin assessed as assessed as decrease in p-nitrophenol production using N-Z-L-Tyr-ONp as subs...				J Med Chem 21: 1202-7 (1979) BindingDB Entry DOI: 10.7270/Q2ST7RCQ
					More data for this Ligand-Target Pair
Prothrombin (Homo sapiens (Human))	BDBM50010243 (CHEMBL3247180) Show SMILES NC(=[NH2+])c1ccc(cc1)[N+]([O-])=O Show InChI InChI=1S/C7H7N3O2/c8-7(9)5-1-3-6(4-2-5)10(11)12/h1-4H,(H3,8,9)/p+1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Similars	PubMed	1.30E+5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Competitive inhibition of esterase activity of human thrombin assessed as decrease in p-nitrophenol production using Nalpha-Z-L-Lys-ONp as substrate ...				J Med Chem 21: 1202-7 (1979) BindingDB Entry DOI: 10.7270/Q2ST7RCQ
					More data for this Ligand-Target Pair
Prothrombin (Homo sapiens (Human))	BDBM50153443 (4-(HYDROXYMETHYL)BENZAMIDINE | 4-Hydroxymethyl-ben...) Show SMILES NC(=N)c1ccc(CO)cc1 Show InChI InChI=1S/C8H10N2O/c9-8(10)7-3-1-6(5-11)2-4-7/h1-4,11H,5H2,(H3,9,10)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MMDB PC cid PC sid PDB UniChem Patents	PubMed	1.58E+5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Competitive inhibition of esterase activity of human thrombin assessed as decrease in p-nitrophenol production using Nalpha-Z-L-Tyr-ONp as substrate ...				J Med Chem 21: 1202-7 (1979) BindingDB Entry DOI: 10.7270/Q2ST7RCQ
					More data for this Ligand-Target Pair
Complement C1s subcomponent (Homo sapiens (Human))	BDBM50010257 (CHEMBL1231012) Show SMILES NC(=N)c1ccc(CC(=O)C(O)=O)cc1 Show InChI InChI=1S/C10H10N2O3/c11-9(12)7-3-1-6(2-4-7)5-8(13)10(14)15/h1-4H,5H2,(H3,11,12)(H,14,15)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL DrugBank KEGG PC cid PC sid UniChem Similars	PubMed	1.58E+5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Competitive inhibition of esterase activity of human activated C1s subunit of first complement component assessed as decrease in p-nitrophenol produc...				J Med Chem 21: 1202-7 (1979) BindingDB Entry DOI: 10.7270/Q2ST7RCQ
					More data for this Ligand-Target Pair
Prothrombin (Homo sapiens (Human))	BDBM50010247 (CHEMBL3247184) Show SMILES NC(=N)c1cccc(c1)C(O)=O Show InChI InChI=1S/C8H8N2O2/c9-7(10)5-2-1-3-6(4-5)8(11)12/h1-4H,(H3,9,10)(H,11,12)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem	PubMed	1.58E+5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Competitive inhibition of esterase activity of human thrombin assessed as decrease in p-nitrophenol production using Nalpha-Z-L-Lys-ONp as substrate ...				J Med Chem 21: 1202-7 (1979) BindingDB Entry DOI: 10.7270/Q2ST7RCQ
					More data for this Ligand-Target Pair
Complement C1s subcomponent (Homo sapiens (Human))	BDBM50010253 (CHEMBL3247189) Show SMILES COc1cccc(c1)C(N)=N Show InChI InChI=1S/C8H10N2O/c1-11-7-4-2-3-6(5-7)8(9)10/h2-5H,1H3,(H3,9,10)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem	PubMed	1.60E+5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Competitive inhibition of esterase activity of human activated C1s subunit of first complement component assessed as decrease in p-nitrophenol produc...				J Med Chem 21: 1202-7 (1979) BindingDB Entry DOI: 10.7270/Q2ST7RCQ
					More data for this Ligand-Target Pair
Plasminogen (Homo sapiens (Human))	BDBM50010245 (CHEMBL3247182) Show SMILES Cc1ccccc1C(N)=N Show InChI InChI=1S/C8H10N2/c1-6-4-2-3-5-7(6)8(9)10/h2-5H,1H3,(H3,9,10)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Similars	PubMed	1.99E+5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Competitive inhibition of esterase activity of human thrombin assessed as decrease in p-nitrophenol production using Nalpha-Z-L-Lys-ONp as substrate ...				J Med Chem 21: 1202-7 (1979) BindingDB Entry DOI: 10.7270/Q2ST7RCQ
					More data for this Ligand-Target Pair
Plasminogen (Homo sapiens (Human))	BDBM50010256 (CHEMBL3247192) Show SMILES Cc1cc(C)cc(c1)C(N)=N Show InChI InChI=1S/C9H12N2/c1-6-3-7(2)5-8(4-6)9(10)11/h3-5H,1-2H3,(H3,10,11)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Similars	PubMed	2.50E+5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Competitive inhibition of esterase activity of human activated C1s subunit of first complement component assessed as decrease in p-nitrophenol produc...				J Med Chem 21: 1202-7 (1979) BindingDB Entry DOI: 10.7270/Q2ST7RCQ
					More data for this Ligand-Target Pair
Complement C1s subcomponent (Homo sapiens (Human))	BDBM50010303 (CHEMBL3247194) Show SMILES NC(=N)c1cccc(CC(=O)C(O)=O)c1 Show InChI InChI=1S/C10H10N2O3/c11-9(12)7-3-1-2-6(4-7)5-8(13)10(14)15/h1-4H,5H2,(H3,11,12)(H,14,15)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL KEGG PC cid PC sid UniChem Similars	PubMed	2.51E+5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Competitive inhibition of esterase activity of human activated C1s subunit of first complement component assessed as decrease in p-nitrophenol produc...				J Med Chem 21: 1202-7 (1979) BindingDB Entry DOI: 10.7270/Q2ST7RCQ
					More data for this Ligand-Target Pair
Prothrombin (Homo sapiens (Human))	BDBM8527 (n,n-dimethyl, m-aminobenzamidine) Show SMILES CN(C)c1cccc(c1)C(N)=N Show InChI InChI=1S/C9H13N3/c1-12(2)8-5-3-4-7(6-8)9(10)11/h3-6H,1-2H3,(H3,10,11)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem	PubMed	2.51E+5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Competitive inhibition of esterase activity of human plasmin assessed as assessed as decrease in p-nitrophenol production using N-Z-L-Tyr-ONp as subs...				J Med Chem 21: 1202-7 (1979) BindingDB Entry DOI: 10.7270/Q2ST7RCQ
					More data for this Ligand-Target Pair
Prothrombin (Homo sapiens (Human))	BDBM50010252 (CHEMBL3247187) Show SMILES NC(=N)c1cccc(c1)-c1ccccc1 Show InChI InChI=1S/C13H12N2/c14-13(15)12-8-4-7-11(9-12)10-5-2-1-3-6-10/h1-9H,(H3,14,15)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	PubMed	3.16E+5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Competitive inhibition of esterase activity of human plasmin assessed as assessed as decrease in p-nitrophenol production using N-Z-L-Tyr-ONp as subs...				J Med Chem 21: 1202-7 (1979) BindingDB Entry DOI: 10.7270/Q2ST7RCQ
					More data for this Ligand-Target Pair
Complement C1s subcomponent (Homo sapiens (Human))	BDBM50010250 (CHEMBL3247186) Show SMILES Cl.NC(=N)c1cccc(N)c1 Show InChI InChI=1S/C7H9N3.ClH/c8-6-3-1-2-5(4-6)7(9)10;/h1-4H,8H2,(H3,9,10);1H	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem	PubMed	3.16E+5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Competitive inhibition of esterase activity of human plasmin assessed as assessed as decrease in p-nitrophenol production using N-Z-L-Tyr-ONp as subs...				J Med Chem 21: 1202-7 (1979) BindingDB Entry DOI: 10.7270/Q2ST7RCQ
					More data for this Ligand-Target Pair
Prothrombin (Homo sapiens (Human))	BDBM50038002 (Benzamidine (Protonated) | CHEMBL20936 | CHEMBL537...) Show SMILES NC(=N)c1ccccc1 Show InChI InChI=1S/C7H8N2/c8-7(9)6-4-2-1-3-5-6/h1-5H,(H3,8,9)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE KEGG MMDB PC cid PC sid UniChem Patents Similars	PubMed	3.16E+5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Competitive inhibition of esterase activity of human plasmin assessed as assessed as decrease in p-nitrophenol production using N-Z-L-Tyr-ONp as subs...				J Med Chem 21: 1202-7 (1979) BindingDB Entry DOI: 10.7270/Q2ST7RCQ
					More data for this Ligand-Target Pair
Complement C1s subcomponent (Homo sapiens (Human))	BDBM50038002 (Benzamidine (Protonated) | CHEMBL20936 | CHEMBL537...) Show SMILES NC(=N)c1ccccc1 Show InChI InChI=1S/C7H8N2/c8-7(9)6-4-2-1-3-5-6/h1-5H,(H3,8,9)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE KEGG MMDB PC cid PC sid UniChem Patents Similars	PubMed	3.98E+5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Competitive inhibition of esterase activity of human plasmin assessed as assessed as decrease in p-nitrophenol production using N-Z-L-Tyr-ONp as subs...				J Med Chem 21: 1202-7 (1979) BindingDB Entry DOI: 10.7270/Q2ST7RCQ
					More data for this Ligand-Target Pair
Plasminogen (Homo sapiens (Human))	BDBM50010244 (CHEMBL3247181) Show SMILES NC(=N)c1cccc(CO)c1 Show InChI InChI=1S/C8H10N2O/c9-8(10)7-3-1-2-6(4-7)5-11/h1-4,11H,5H2,(H3,9,10)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem	PubMed	3.98E+5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Competitive inhibition of esterase activity of human thrombin assessed as decrease in p-nitrophenol production using Nalpha-Z-L-Lys-ONp as substrate ...				J Med Chem 21: 1202-7 (1979) BindingDB Entry DOI: 10.7270/Q2ST7RCQ
					More data for this Ligand-Target Pair
Plasminogen (Homo sapiens (Human))	BDBM50038002 (Benzamidine (Protonated) | CHEMBL20936 | CHEMBL537...) Show SMILES NC(=N)c1ccccc1 Show InChI InChI=1S/C7H8N2/c8-7(9)6-4-2-1-3-5-6/h1-5H,(H3,8,9)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE KEGG MMDB PC cid PC sid UniChem Patents Similars	PubMed	5.00E+5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Competitive inhibition of esterase activity of human plasmin assessed as assessed as decrease in p-nitrophenol production using N-Z-L-Tyr-ONp as subs...				J Med Chem 21: 1202-7 (1979) BindingDB Entry DOI: 10.7270/Q2ST7RCQ
					More data for this Ligand-Target Pair
Prothrombin (Homo sapiens (Human))	BDBM50010250 (CHEMBL3247186) Show SMILES Cl.NC(=N)c1cccc(N)c1 Show InChI InChI=1S/C7H9N3.ClH/c8-6-3-1-2-5(4-6)7(9)10;/h1-4H,8H2,(H3,9,10);1H	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem	PubMed	5.01E+5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Competitive inhibition of esterase activity of human plasmin assessed as assessed as decrease in p-nitrophenol production using N-Z-L-Tyr-ONp as subs...				J Med Chem 21: 1202-7 (1979) BindingDB Entry DOI: 10.7270/Q2ST7RCQ
					More data for this Ligand-Target Pair
Prothrombin (Homo sapiens (Human))	BDBM50010255 (CHEMBL3247191) Show SMILES NC(=N)c1cccc(Br)c1 Show InChI InChI=1S/C7H7BrN2/c8-6-3-1-2-5(4-6)7(9)10/h1-4H,(H3,9,10)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem	PubMed	6.30E+5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Competitive inhibition of esterase activity of human activated C1s subunit of first complement component assessed as decrease in p-nitrophenol produc...				J Med Chem 21: 1202-7 (1979) BindingDB Entry DOI: 10.7270/Q2ST7RCQ
					More data for this Ligand-Target Pair
Complement C1s subcomponent (Homo sapiens (Human))	BDBM50010249 (CHEMBL3247185) Show SMILES NC(=N)c1cccc(Cc2ccccc2)c1 Show InChI InChI=1S/C14H14N2/c15-14(16)13-8-4-7-12(10-13)9-11-5-2-1-3-6-11/h1-8,10H,9H2,(H3,15,16)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	PubMed	6.30E+5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Competitive inhibition of esterase activity of human plasmin assessed as assessed as decrease in p-nitrophenol production using N-Z-L-Tyr-ONp as subs...				J Med Chem 21: 1202-7 (1979) BindingDB Entry DOI: 10.7270/Q2ST7RCQ
					More data for this Ligand-Target Pair
Plasminogen (Homo sapiens (Human))	BDBM50010253 (CHEMBL3247189) Show SMILES COc1cccc(c1)C(N)=N Show InChI InChI=1S/C8H10N2O/c1-11-7-4-2-3-6(5-7)8(9)10/h2-5H,1H3,(H3,9,10)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem	PubMed	6.30E+5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Competitive inhibition of esterase activity of human plasmin assessed as assessed as decrease in p-nitrophenol production using N-Z-L-Tyr-ONp as subs...				J Med Chem 21: 1202-7 (1979) BindingDB Entry DOI: 10.7270/Q2ST7RCQ
					More data for this Ligand-Target Pair
Complement C1s subcomponent (Homo sapiens (Human))	BDBM50010256 (CHEMBL3247192) Show SMILES Cc1cc(C)cc(c1)C(N)=N Show InChI InChI=1S/C9H12N2/c1-6-3-7(2)5-8(4-6)9(10)11/h3-5H,1-2H3,(H3,10,11)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Similars	PubMed	6.30E+5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Competitive inhibition of esterase activity of human activated C1s subunit of first complement component assessed as decrease in p-nitrophenol produc...				J Med Chem 21: 1202-7 (1979) BindingDB Entry DOI: 10.7270/Q2ST7RCQ
					More data for this Ligand-Target Pair
Complement C1s subcomponent (Homo sapiens (Human))	BDBM50010255 (CHEMBL3247191) Show SMILES NC(=N)c1cccc(Br)c1 Show InChI InChI=1S/C7H7BrN2/c8-6-3-1-2-5(4-6)7(9)10/h1-4H,(H3,9,10)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem	PubMed	6.30E+5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Competitive inhibition of esterase activity of human activated C1s subunit of first complement component assessed as decrease in p-nitrophenol produc...				J Med Chem 21: 1202-7 (1979) BindingDB Entry DOI: 10.7270/Q2ST7RCQ
					More data for this Ligand-Target Pair
Prothrombin (Homo sapiens (Human))	BDBM50010246 (CHEMBL3247183) Show SMILES Cl.NC(=[NH2+])c1cccc(c1)[N+]([O-])=O Show InChI InChI=1S/C7H7N3O2.ClH/c8-7(9)5-2-1-3-6(4-5)10(11)12;/h1-4H,(H3,8,9);1H/p+1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem	PubMed	7.94E+5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Competitive inhibition of esterase activity of human thrombin assessed as decrease in p-nitrophenol production using Nalpha-Z-L-Lys-ONp as substrate ...				J Med Chem 21: 1202-7 (1979) BindingDB Entry DOI: 10.7270/Q2ST7RCQ
					More data for this Ligand-Target Pair
Prothrombin (Homo sapiens (Human))	BDBM50010304 (CHEMBL3247195) Show SMILES NC(=N)c1cccc(c1)C(=N)Nc1cccc2ccccc12 Show InChI InChI=1S/C18H16N4/c19-17(20)13-7-3-8-14(11-13)18(21)22-16-10-4-6-12-5-1-2-9-15(12)16/h1-11H,(H3,19,20)(H2,21,22)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	PubMed	9.99E+5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Competitive inhibition of esterase activity of human thrombin assessed as decrease in p-nitrophenol production using Nalpha-Z-L-Tyr-ONp as substrate ...				J Med Chem 21: 1202-7 (1979) BindingDB Entry DOI: 10.7270/Q2ST7RCQ
					More data for this Ligand-Target Pair
Prothrombin (Homo sapiens (Human))	BDBM50153443 (4-(HYDROXYMETHYL)BENZAMIDINE | 4-Hydroxymethyl-ben...) Show SMILES NC(=N)c1ccc(CO)cc1 Show InChI InChI=1S/C8H10N2O/c9-8(10)7-3-1-6(5-11)2-4-7/h1-4,11H,5H2,(H3,9,10)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MMDB PC cid PC sid PDB UniChem Patents	PubMed	9.99E+5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Competitive inhibition of esterase activity of human thrombin assessed as decrease in p-nitrophenol production using Nalpha-Z-L-Tyr-ONp as substrate ...				J Med Chem 21: 1202-7 (1979) BindingDB Entry DOI: 10.7270/Q2ST7RCQ
					More data for this Ligand-Target Pair
Prothrombin (Homo sapiens (Human))	BDBM50010246 (CHEMBL3247183) Show SMILES Cl.NC(=[NH2+])c1cccc(c1)[N+]([O-])=O Show InChI InChI=1S/C7H7N3O2.ClH/c8-7(9)5-2-1-3-6(4-5)10(11)12;/h1-4H,(H3,8,9);1H/p+1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem	PubMed	1.58E+6	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Competitive inhibition of esterase activity of human thrombin assessed as decrease in p-nitrophenol production using Nalpha-Z-L-Lys-ONp as substrate ...				J Med Chem 21: 1202-7 (1979) BindingDB Entry DOI: 10.7270/Q2ST7RCQ
					More data for this Ligand-Target Pair
Plasminogen (Homo sapiens (Human))	BDBM50010247 (CHEMBL3247184) Show SMILES NC(=N)c1cccc(c1)C(O)=O Show InChI InChI=1S/C8H8N2O2/c9-7(10)5-2-1-3-6(4-5)8(11)12/h1-4H,(H3,9,10)(H,11,12)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem	PubMed	1.58E+6	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Competitive inhibition of esterase activity of human thrombin assessed as decrease in p-nitrophenol production using Nalpha-Z-L-Lys-ONp as substrate ...				J Med Chem 21: 1202-7 (1979) BindingDB Entry DOI: 10.7270/Q2ST7RCQ
					More data for this Ligand-Target Pair
Plasminogen (Homo sapiens (Human))	BDBM50010246 (CHEMBL3247183) Show SMILES Cl.NC(=[NH2+])c1cccc(c1)[N+]([O-])=O Show InChI InChI=1S/C7H7N3O2.ClH/c8-7(9)5-2-1-3-6(4-5)10(11)12;/h1-4H,(H3,8,9);1H/p+1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem	PubMed	1.58E+6	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Competitive inhibition of esterase activity of human thrombin assessed as decrease in p-nitrophenol production using Nalpha-Z-L-Lys-ONp as substrate ...				J Med Chem 21: 1202-7 (1979) BindingDB Entry DOI: 10.7270/Q2ST7RCQ
					More data for this Ligand-Target Pair

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