Compile Data Set for Download or QSAR

Found 113 hits with Last Name = 'andronati' and Initial = 's'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Integrin alpha-IIb/beta-3 (Homo sapiens (Human))	BDBM50155250 (3-[3-(2,3-Dihydro-1H-isoindol-5-ylcarbamoyl)-propi...) Show SMILES OC(=O)CC(NC(=O)CCC(=O)Nc1ccc2CNCc2c1)c1ccccc1 Show InChI InChI=1S/C21H23N3O4/c25-19(23-17-7-6-15-12-22-13-16(15)10-17)8-9-20(26)24-18(11-21(27)28)14-4-2-1-3-5-14/h1-7,10,18,22H,8-9,11-13H2,(H,23,25)(H,24,26)(H,27,28)	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	4.20	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
A.V. Bogatsky Physico-Chemical Institute of the National Academy of Sciences of Ukraine Curated by ChEMBL					Assay Description In vitro binding affinity for FITC-labeled fibrinogen binding to alphaIIb-beta3 receptor of human platelets				Bioorg Med Chem Lett 14: 5533-5 (2004) Article DOI: 10.1016/j.bmcl.2004.09.002 BindingDB Entry DOI: 10.7270/Q2J38T9M
					More data for this Ligand-Target Pair
Integrin alpha-IIb/beta-3 (Homo sapiens (Human))	BDBM50155251 (3-[3-(2,3-Dihydro-1H-isoindol-5-ylcarbamoyl)-propi...) Show SMILES OC(=O)CCNC(=O)CCC(=O)Nc1ccc2CNCc2c1 Show InChI InChI=1S/C15H19N3O4/c19-13(17-6-5-15(21)22)3-4-14(20)18-12-2-1-10-8-16-9-11(10)7-12/h1-2,7,16H,3-6,8-9H2,(H,17,19)(H,18,20)(H,21,22)	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	7.10	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
A.V. Bogatsky Physico-Chemical Institute of the National Academy of Sciences of Ukraine Curated by ChEMBL					Assay Description In vitro binding affinity for FITC-labeled fibrinogen binding to alphaIIb-beta3 receptor of human platelets				Bioorg Med Chem Lett 14: 5533-5 (2004) Article DOI: 10.1016/j.bmcl.2004.09.002 BindingDB Entry DOI: 10.7270/Q2J38T9M
					More data for this Ligand-Target Pair
Integrin alpha-3/beta-3 (Homo sapiens (Human))	BDBM50482402 (CHEMBL1209692) Show SMILES OC(=O)CC(NC(=O)CCC(=O)Nc1ccc2CNCc2c1)c1ccc2OCOc2c1 Show InChI InChI=1S/C22H23N3O6/c26-20(24-16-3-1-14-10-23-11-15(14)7-16)5-6-21(27)25-17(9-22(28)29)13-2-4-18-19(8-13)31-12-30-18/h1-4,7-8,17,23H,5-6,9-12H2,(H,24,26)(H,25,27)(H,28,29)	PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	0.220	n/a	n/a	n/a	n/a	n/a	n/a
A.V. Bogatsky Physico-Chemical Institute of the National Academy of Sciences of Ukraine Curated by ChEMBL					Assay Description Antagonist activity at FITC-tagged alpha3beta3 integrin in human platelet assessed as reduction of ADP-induced platelet aggregation				Bioorg Med Chem Lett 20: 4444-6 (2010) Article DOI: 10.1016/j.bmcl.2010.06.051 BindingDB Entry DOI: 10.7270/Q2H134T5
					More data for this Ligand-Target Pair
Integrin alpha-3/beta-3 (Homo sapiens (Human))	BDBM50482409 (CHEMBL1208912) Show SMILES Cl.OC(=O)CC(NC(=O)CCC(=O)Nc1ccc2CCNCc2c1)c1ccc2OCOc2c1 Show InChI InChI=1S/C23H25N3O6.ClH/c27-21(25-17-3-1-14-7-8-24-12-16(14)9-17)5-6-22(28)26-18(11-23(29)30)15-2-4-19-20(10-15)32-13-31-19;/h1-4,9-10,18,24H,5-8,11-13H2,(H,25,27)(H,26,28)(H,29,30);1H	PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	0.400	n/a	n/a	n/a	n/a	n/a	n/a
A.V. Bogatsky Physico-Chemical Institute of the National Academy of Sciences of Ukraine Curated by ChEMBL					Assay Description Antagonist activity at FITC-tagged alpha3beta3 integrin in human platelet assessed as reduction of ADP-induced platelet aggregation				Bioorg Med Chem Lett 20: 4444-6 (2010) Article DOI: 10.1016/j.bmcl.2010.06.051 BindingDB Entry DOI: 10.7270/Q2H134T5
					More data for this Ligand-Target Pair
Integrin alpha-3/beta-3 (Homo sapiens (Human))	BDBM50482414 (CHEMBL1208853) Show SMILES Cl.COc1ccc(cc1OC)C(CC(O)=O)NC(=O)CCC(=O)Nc1ccc2CCNCc2c1 Show InChI InChI=1S/C24H29N3O6.ClH/c1-32-20-6-4-16(12-21(20)33-2)19(13-24(30)31)27-23(29)8-7-22(28)26-18-5-3-15-9-10-25-14-17(15)11-18;/h3-6,11-12,19,25H,7-10,13-14H2,1-2H3,(H,26,28)(H,27,29)(H,30,31);1H	PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	0.630	n/a	n/a	n/a	n/a	n/a	n/a
A.V. Bogatsky Physico-Chemical Institute of the National Academy of Sciences of Ukraine Curated by ChEMBL					Assay Description Antagonist activity at FITC-tagged alpha3beta3 integrin in human platelet assessed as reduction of ADP-induced platelet aggregation				Bioorg Med Chem Lett 20: 4444-6 (2010) Article DOI: 10.1016/j.bmcl.2010.06.051 BindingDB Entry DOI: 10.7270/Q2H134T5
					More data for this Ligand-Target Pair
Integrin alpha-2/beta-3 (Homo sapiens (Human))	BDBM50323320 (3-(3,4-dimethoxyphenyl)-3-(3-(1,2,3,4-tetrahydrois...) Show SMILES COc1ccc(cc1OC)C(CC(O)=O)NC(=O)c1cccc(c1)C(=O)Nc1ccc2CCNCc2c1 Show InChI InChI=1S/C28H29N3O6/c1-36-24-9-7-18(14-25(24)37-2)23(15-26(32)33)31-28(35)20-5-3-4-19(12-20)27(34)30-22-8-6-17-10-11-29-16-21(17)13-22/h3-9,12-14,23,29H,10-11,15-16H2,1-2H3,(H,30,34)(H,31,35)(H,32,33)	PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	0.700	n/a	n/a	n/a	n/a	n/a	n/a
A.V. Bogatsky Physico-Chemical Institute of the National Academy of Sciences of Ukraine Curated by ChEMBL					Assay Description Displacement of FITC-Fg from integrin alpha2beta3 receptor expressed in human activated platelets				Bioorg Med Chem Lett 16: 5294-7 (2006) Article DOI: 10.1016/j.bmcl.2006.07.090 BindingDB Entry DOI: 10.7270/Q2MW2HZP
					More data for this Ligand-Target Pair
Integrin alpha-3/beta-3 (Homo sapiens (Human))	BDBM50323320 (3-(3,4-dimethoxyphenyl)-3-(3-(1,2,3,4-tetrahydrois...) Show SMILES COc1ccc(cc1OC)C(CC(O)=O)NC(=O)c1cccc(c1)C(=O)Nc1ccc2CCNCc2c1 Show InChI InChI=1S/C28H29N3O6/c1-36-24-9-7-18(14-25(24)37-2)23(15-26(32)33)31-28(35)20-5-3-4-19(12-20)27(34)30-22-8-6-17-10-11-29-16-21(17)13-22/h3-9,12-14,23,29H,10-11,15-16H2,1-2H3,(H,30,34)(H,31,35)(H,32,33)	PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	0.700	n/a	n/a	n/a	n/a	n/a	n/a
A.V. Bogatsky Physico-Chemical Institute of the National Academy of Sciences of Ukraine Curated by ChEMBL					Assay Description Antagonist activity at FITC-tagged alpha3beta3 integrin in human platelet assessed as reduction of ADP-induced platelet aggregation				Bioorg Med Chem Lett 20: 4444-6 (2010) Article DOI: 10.1016/j.bmcl.2010.06.051 BindingDB Entry DOI: 10.7270/Q2H134T5
					More data for this Ligand-Target Pair
Integrin alpha-3/beta-3 (Homo sapiens (Human))	BDBM50482419 (CHEMBL1208980) Show SMILES Cl.OC(=O)CC(NC(=O)CCCC(=O)Nc1ccc2CCNCc2c1)c1ccc2OCOc2c1 Show InChI InChI=1S/C24H27N3O6.ClH/c28-22(26-18-6-4-15-8-9-25-13-17(15)10-18)2-1-3-23(29)27-19(12-24(30)31)16-5-7-20-21(11-16)33-14-32-20;/h4-7,10-11,19,25H,1-3,8-9,12-14H2,(H,26,28)(H,27,29)(H,30,31);1H	PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	0.780	n/a	n/a	n/a	n/a	n/a	n/a
A.V. Bogatsky Physico-Chemical Institute of the National Academy of Sciences of Ukraine Curated by ChEMBL					Assay Description Antagonist activity at FITC-tagged alpha3beta3 integrin in human platelet assessed as reduction of ADP-induced platelet aggregation				Bioorg Med Chem Lett 20: 4444-6 (2010) Article DOI: 10.1016/j.bmcl.2010.06.051 BindingDB Entry DOI: 10.7270/Q2H134T5
					More data for this Ligand-Target Pair
Integrin alpha-3/beta-3 (Homo sapiens (Human))	BDBM50323319 (3-(3-(carbamoyl)benzamido)-3-(4-methoxyphenyl)prop...) Show SMILES COc1ccc(cc1)C(CC(O)=O)NC(=O)c1cccc(c1)C(=O)Nc1ccc2CCNCc2c1 Show InChI InChI=1S/C27H27N3O5/c1-35-23-9-6-18(7-10-23)24(15-25(31)32)30-27(34)20-4-2-3-19(13-20)26(33)29-22-8-5-17-11-12-28-16-21(17)14-22/h2-10,13-14,24,28H,11-12,15-16H2,1H3,(H,29,33)(H,30,34)(H,31,32)	PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	0.800	n/a	n/a	n/a	n/a	n/a	n/a
A.V. Bogatsky Physico-Chemical Institute of the National Academy of Sciences of Ukraine Curated by ChEMBL					Assay Description Antagonist activity at FITC-tagged alpha3beta3 integrin in human platelet assessed as reduction of ADP-induced platelet aggregation				Bioorg Med Chem Lett 20: 4444-6 (2010) Article DOI: 10.1016/j.bmcl.2010.06.051 BindingDB Entry DOI: 10.7270/Q2H134T5
					More data for this Ligand-Target Pair
Integrin alpha-2/beta-3 (Homo sapiens (Human))	BDBM50323319 (3-(3-(carbamoyl)benzamido)-3-(4-methoxyphenyl)prop...) Show SMILES COc1ccc(cc1)C(CC(O)=O)NC(=O)c1cccc(c1)C(=O)Nc1ccc2CCNCc2c1 Show InChI InChI=1S/C27H27N3O5/c1-35-23-9-6-18(7-10-23)24(15-25(31)32)30-27(34)20-4-2-3-19(13-20)26(33)29-22-8-5-17-11-12-28-16-21(17)14-22/h2-10,13-14,24,28H,11-12,15-16H2,1H3,(H,29,33)(H,30,34)(H,31,32)	PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	0.800	n/a	n/a	n/a	n/a	n/a	n/a
A.V. Bogatsky Physico-Chemical Institute of the National Academy of Sciences of Ukraine Curated by ChEMBL					Assay Description Displacement of FITC-Fg from integrin alpha2beta3 receptor expressed in human activated platelets				Bioorg Med Chem Lett 16: 5294-7 (2006) Article DOI: 10.1016/j.bmcl.2006.07.090 BindingDB Entry DOI: 10.7270/Q2MW2HZP
					More data for this Ligand-Target Pair
Integrin alpha-3/beta-3 (Homo sapiens (Human))	BDBM50482412 (CHEMBL1208850) Show SMILES Cl.Cc1ccc(cc1)C(CC(O)=O)NC(=O)CCC(=O)Nc1ccc2CCNCc2c1 Show InChI InChI=1S/C23H27N3O4.ClH/c1-15-2-4-17(5-3-15)20(13-23(29)30)26-22(28)9-8-21(27)25-19-7-6-16-10-11-24-14-18(16)12-19;/h2-7,12,20,24H,8-11,13-14H2,1H3,(H,25,27)(H,26,28)(H,29,30);1H	PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	0.900	n/a	n/a	n/a	n/a	n/a	n/a
A.V. Bogatsky Physico-Chemical Institute of the National Academy of Sciences of Ukraine Curated by ChEMBL					Assay Description Antagonist activity at FITC-tagged alpha3beta3 integrin in human platelet assessed as reduction of ADP-induced platelet aggregation				Bioorg Med Chem Lett 20: 4444-6 (2010) Article DOI: 10.1016/j.bmcl.2010.06.051 BindingDB Entry DOI: 10.7270/Q2H134T5
					More data for this Ligand-Target Pair
Integrin alpha-2/beta-3 (Homo sapiens (Human))	BDBM50323318 (3-(3-(carbamoyl)benzamido)-3-phenylpropanoic acid ...) Show SMILES OC(=O)CC(NC(=O)c1cccc(c1)C(=O)Nc1ccc2CCNCc2c1)c1ccccc1 Show InChI InChI=1S/C26H25N3O4/c30-24(31)15-23(18-5-2-1-3-6-18)29-26(33)20-8-4-7-19(13-20)25(32)28-22-10-9-17-11-12-27-16-21(17)14-22/h1-10,13-14,23,27H,11-12,15-16H2,(H,28,32)(H,29,33)(H,30,31)	PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1	n/a	n/a	n/a	n/a	n/a	n/a
A.V. Bogatsky Physico-Chemical Institute of the National Academy of Sciences of Ukraine Curated by ChEMBL					Assay Description Displacement of FITC-Fg from integrin alpha2beta3 receptor expressed in human activated platelets				Bioorg Med Chem Lett 16: 5294-7 (2006) Article DOI: 10.1016/j.bmcl.2006.07.090 BindingDB Entry DOI: 10.7270/Q2MW2HZP
					More data for this Ligand-Target Pair
Integrin alpha-3/beta-3 (Homo sapiens (Human))	BDBM50482404 (CHEMBL1209860) Show SMILES Cl.OC(=O)CC(NC(=O)CCC(=O)Nc1ccc2CCNCc2c1)c1ccc(F)cc1 Show InChI InChI=1S/C22H24FN3O4.ClH/c23-17-4-1-15(2-5-17)19(12-22(29)30)26-21(28)8-7-20(27)25-18-6-3-14-9-10-24-13-16(14)11-18;/h1-6,11,19,24H,7-10,12-13H2,(H,25,27)(H,26,28)(H,29,30);1H	PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1	n/a	n/a	n/a	n/a	n/a	n/a
A.V. Bogatsky Physico-Chemical Institute of the National Academy of Sciences of Ukraine Curated by ChEMBL					Assay Description Antagonist activity at FITC-tagged alpha3beta3 integrin in human platelet assessed as reduction of ADP-induced platelet aggregation				Bioorg Med Chem Lett 20: 4444-6 (2010) Article DOI: 10.1016/j.bmcl.2010.06.051 BindingDB Entry DOI: 10.7270/Q2H134T5
					More data for this Ligand-Target Pair
Integrin alpha-3/beta-3 (Homo sapiens (Human))	BDBM50323318 (3-(3-(carbamoyl)benzamido)-3-phenylpropanoic acid ...) Show SMILES OC(=O)CC(NC(=O)c1cccc(c1)C(=O)Nc1ccc2CCNCc2c1)c1ccccc1 Show InChI InChI=1S/C26H25N3O4/c30-24(31)15-23(18-5-2-1-3-6-18)29-26(33)20-8-4-7-19(13-20)25(32)28-22-10-9-17-11-12-27-16-21(17)14-22/h1-10,13-14,23,27H,11-12,15-16H2,(H,28,32)(H,29,33)(H,30,31)	PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1	n/a	n/a	n/a	n/a	n/a	n/a
A.V. Bogatsky Physico-Chemical Institute of the National Academy of Sciences of Ukraine Curated by ChEMBL					Assay Description Antagonist activity at FITC-tagged alpha3beta3 integrin in human platelet assessed as reduction of ADP-induced platelet aggregation				Bioorg Med Chem Lett 20: 4444-6 (2010) Article DOI: 10.1016/j.bmcl.2010.06.051 BindingDB Entry DOI: 10.7270/Q2H134T5
					More data for this Ligand-Target Pair
Integrin alpha-3/beta-3 (Homo sapiens (Human))	BDBM50482403 (CHEMBL1209774) Show SMILES Cl.OC(=O)CC(NC(=O)CCC(=O)Nc1ccc2CCNCc2c1)c1ccccc1 Show InChI InChI=1S/C22H25N3O4.ClH/c26-20(24-18-7-6-15-10-11-23-14-17(15)12-18)8-9-21(27)25-19(13-22(28)29)16-4-2-1-3-5-16;/h1-7,12,19,23H,8-11,13-14H2,(H,24,26)(H,25,27)(H,28,29);1H	PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1	n/a	n/a	n/a	n/a	n/a	n/a
A.V. Bogatsky Physico-Chemical Institute of the National Academy of Sciences of Ukraine Curated by ChEMBL					Assay Description Antagonist activity at FITC-tagged alpha3beta3 integrin in human platelet assessed as reduction of ADP-induced platelet aggregation				Bioorg Med Chem Lett 20: 4444-6 (2010) Article DOI: 10.1016/j.bmcl.2010.06.051 BindingDB Entry DOI: 10.7270/Q2H134T5
					More data for this Ligand-Target Pair
Integrin alpha-3/beta-3 (Homo sapiens (Human))	BDBM50482415 (CHEMBL1209773) Show SMILES Cl.OC(=O)CCNC(=O)CCC(=O)Nc1ccc2CCNCc2c1 Show InChI InChI=1S/C16H21N3O4/c20-14(18-8-6-16(22)23)3-4-15(21)19-13-2-1-11-5-7-17-10-12(11)9-13/h1-2,9,17H,3-8,10H2,(H,18,20)(H,19,21)(H,22,23)	PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.20	n/a	n/a	n/a	n/a	n/a	n/a
A.V. Bogatsky Physico-Chemical Institute of the National Academy of Sciences of Ukraine Curated by ChEMBL					Assay Description Antagonist activity at FITC-tagged alpha3beta3 integrin in human platelet assessed as reduction of ADP-induced platelet aggregation				Bioorg Med Chem Lett 20: 4444-6 (2010) Article DOI: 10.1016/j.bmcl.2010.06.051 BindingDB Entry DOI: 10.7270/Q2H134T5
					More data for this Ligand-Target Pair
Integrin alpha-IIb/beta-3 (Homo sapiens (Human))	BDBM50156364 (CHEMBL3786107) Show SMILES Cl.Cl.NC[C@H](NC(=O)OCc1ccccc1)C(=O)Nc1ccc2nc([nH]c(=O)c2c1)N1CCNCC1 |r| Show InChI InChI=1S/C23H27N7O4.2ClH/c24-13-19(28-23(33)34-14-15-4-2-1-3-5-15)21(32)26-16-6-7-18-17(12-16)20(31)29-22(27-18)30-10-8-25-9-11-30;;/h1-7,12,19,25H,8-11,13-14,24H2,(H,26,32)(H,28,33)(H,27,29,31);2*1H/t19-;;/m0../s1	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	1.5	n/a	n/a	n/a	n/a	n/a	n/a
A.V. Bogatsky Physico-Chemical Institute of the National Academy of Sciences of Ukraine Curated by ChEMBL					Assay Description Inhibition of FITC-labelled fibrinogen binding to integrin alpha2b beta3 receptor in human platelet cells				Bioorg Med Chem Lett 26: 1839-43 (2016) Article DOI: 10.1016/j.bmcl.2016.02.011 BindingDB Entry DOI: 10.7270/Q2NV9M57
					More data for this Ligand-Target Pair
Integrin alpha-IIb/beta-3 (Homo sapiens (Human))	BDBM50156365 (CHEMBL3787524) Show SMILES Cl.Cl.NCC[C@H](NC(=O)OCc1ccccc1)C(=O)Nc1ccc2nc([nH]c(=O)c2c1)N1CCNCC1 |r| Show InChI InChI=1S/C24H29N7O4.2ClH/c25-9-8-20(29-24(34)35-15-16-4-2-1-3-5-16)22(33)27-17-6-7-19-18(14-17)21(32)30-23(28-19)31-12-10-26-11-13-31;;/h1-7,14,20,26H,8-13,15,25H2,(H,27,33)(H,29,34)(H,28,30,32);2*1H/t20-;;/m0../s1	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	1.60	n/a	n/a	n/a	n/a	n/a	n/a
A.V. Bogatsky Physico-Chemical Institute of the National Academy of Sciences of Ukraine Curated by ChEMBL					Assay Description Inhibition of FITC-labelled fibrinogen binding to integrin alpha2b beta3 receptor in human platelet cells				Bioorg Med Chem Lett 26: 1839-43 (2016) Article DOI: 10.1016/j.bmcl.2016.02.011 BindingDB Entry DOI: 10.7270/Q2NV9M57
					More data for this Ligand-Target Pair
Integrin alpha-IIb/beta-3 (Homo sapiens (Human))	BDBM50156363 (CHEMBL3786425) Show SMILES Cl.Cl.CC(C)COC(=O)N[C@@H](CN)C(=O)Nc1ccc2nc([nH]c(=O)c2c1)N1CCNCC1 |r| Show InChI InChI=1S/C20H29N7O4.2ClH/c1-12(2)11-31-20(30)25-16(10-21)18(29)23-13-3-4-15-14(9-13)17(28)26-19(24-15)27-7-5-22-6-8-27;;/h3-4,9,12,16,22H,5-8,10-11,21H2,1-2H3,(H,23,29)(H,25,30)(H,24,26,28);2*1H/t16-;;/m0../s1	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.80	n/a	n/a	n/a	n/a	n/a	n/a
A.V. Bogatsky Physico-Chemical Institute of the National Academy of Sciences of Ukraine Curated by ChEMBL					Assay Description Inhibition of FITC-labelled fibrinogen binding to integrin alpha2b beta3 receptor in human platelet cells				Bioorg Med Chem Lett 26: 1839-43 (2016) Article DOI: 10.1016/j.bmcl.2016.02.011 BindingDB Entry DOI: 10.7270/Q2NV9M57
					More data for this Ligand-Target Pair
Integrin alpha-IIb/beta-3 (Homo sapiens (Human))	BDBM50004058 ((2S)-2-(butylsulfonylamino)-3-[4-(4-piperidin-4-yl...) Show SMILES CCCCS(=O)(=O)N[C@@H](Cc1ccc(OCCCCC2CCNCC2)cc1)C(O)=O Show InChI InChI=1S/C22H36N2O5S/c1-2-3-16-30(27,28)24-21(22(25)26)17-19-7-9-20(10-8-19)29-15-5-4-6-18-11-13-23-14-12-18/h7-10,18,21,23-24H,2-6,11-17H2,1H3,(H,25,26)/t21-/m0/s1	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	Purchase DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	DrugBank PDB Article PubMed	n/a	n/a	1.90	n/a	n/a	n/a	n/a	n/a	n/a
A.V. Bogatsky Physico-Chemical Institute of the National Academy of Sciences of Ukraine Curated by ChEMBL					Assay Description Inhibition of FITC-labelled fibrinogen binding to integrin alpha2b beta3 receptor in human platelet cells				Bioorg Med Chem Lett 26: 1839-43 (2016) Article DOI: 10.1016/j.bmcl.2016.02.011 BindingDB Entry DOI: 10.7270/Q2NV9M57
					More data for this Ligand-Target Pair				3D Structure (crystal)
Integrin alpha-IIb/beta-3 (Homo sapiens (Human))	BDBM50004058 ((2S)-2-(butylsulfonylamino)-3-[4-(4-piperidin-4-yl...) Show SMILES CCCCS(=O)(=O)N[C@@H](Cc1ccc(OCCCCC2CCNCC2)cc1)C(O)=O Show InChI InChI=1S/C22H36N2O5S/c1-2-3-16-30(27,28)24-21(22(25)26)17-19-7-9-20(10-8-19)29-15-5-4-6-18-11-13-23-14-12-18/h7-10,18,21,23-24H,2-6,11-17H2,1H3,(H,25,26)/t21-/m0/s1	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	Purchase DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	DrugBank PDB Article PubMed	n/a	n/a	2.40	n/a	n/a	n/a	n/a	n/a	n/a
A.V. Bogatsky Physico-Chemical Institute of the National Academy of Sciences of Ukraine Curated by ChEMBL					Assay Description Inhibition of FITC-labeled fibrinogen binding to integrin alpha2bbeta3 receptor in human platelets by flow cytometry				Bioorg Med Chem 21: 4646-61 (2013) Article DOI: 10.1016/j.bmc.2013.05.019 BindingDB Entry DOI: 10.7270/Q2Q81FGX
					More data for this Ligand-Target Pair				3D Structure (crystal)
Integrin alpha-3/beta-3 (Homo sapiens (Human))	BDBM50482400 (CHEMBL1209622) Show SMILES COc1ccc(cc1)C(CC(O)=O)NC(=O)CCC(=O)Nc1ccc2CNCc2c1 Show InChI InChI=1S/C22H25N3O5/c1-30-18-6-3-14(4-7-18)19(11-22(28)29)25-21(27)9-8-20(26)24-17-5-2-15-12-23-13-16(15)10-17/h2-7,10,19,23H,8-9,11-13H2,1H3,(H,24,26)(H,25,27)(H,28,29)	PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	2.60	n/a	n/a	n/a	n/a	n/a	n/a
A.V. Bogatsky Physico-Chemical Institute of the National Academy of Sciences of Ukraine Curated by ChEMBL					Assay Description Antagonist activity at FITC-tagged alpha3beta3 integrin in human platelet assessed as reduction of ADP-induced platelet aggregation				Bioorg Med Chem Lett 20: 4444-6 (2010) Article DOI: 10.1016/j.bmcl.2010.06.051 BindingDB Entry DOI: 10.7270/Q2H134T5
					More data for this Ligand-Target Pair
Integrin alpha-3/beta-3 (Homo sapiens (Human))	BDBM50482407 (CHEMBL1208851) Show SMILES Cl.COc1ccc(cc1)C(CC(O)=O)NC(=O)CCC(=O)Nc1ccc2CCNCc2c1 Show InChI InChI=1S/C23H27N3O5.ClH/c1-31-19-6-3-16(4-7-19)20(13-23(29)30)26-22(28)9-8-21(27)25-18-5-2-15-10-11-24-14-17(15)12-18;/h2-7,12,20,24H,8-11,13-14H2,1H3,(H,25,27)(H,26,28)(H,29,30);1H	PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	3.5	n/a	n/a	n/a	n/a	n/a	n/a
A.V. Bogatsky Physico-Chemical Institute of the National Academy of Sciences of Ukraine Curated by ChEMBL					Assay Description Antagonist activity at FITC-tagged alpha3beta3 integrin in human platelet assessed as reduction of ADP-induced platelet aggregation				Bioorg Med Chem Lett 20: 4444-6 (2010) Article DOI: 10.1016/j.bmcl.2010.06.051 BindingDB Entry DOI: 10.7270/Q2H134T5
					More data for this Ligand-Target Pair
Integrin alpha-2/beta-3 (Homo sapiens (Human))	BDBM50370766 (CHEMBL385939) Show SMILES COc1ccc(cc1OC)C(CC(O)=O)NC(=O)c1cc(cc(c1)[N+]([O-])=O)C(=O)Nc1ccc2CCNCc2c1 Show InChI InChI=1S/C28H28N4O8/c1-39-24-6-4-17(13-25(24)40-2)23(14-26(33)34)31-28(36)19-9-18(11-22(12-19)32(37)38)27(35)30-21-5-3-16-7-8-29-15-20(16)10-21/h3-6,9-13,23,29H,7-8,14-15H2,1-2H3,(H,30,35)(H,31,36)(H,33,34)	PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.70	n/a	n/a	n/a	n/a	n/a	n/a
A.V. Bogatsky Physico-Chemical Institute of the National Academy of Sciences of Ukraine Curated by ChEMBL					Assay Description Displacement of FITC-Fg from integrin alpha2beta3 receptor expressed in human activated platelets				Bioorg Med Chem Lett 16: 5294-7 (2006) Article DOI: 10.1016/j.bmcl.2006.07.090 BindingDB Entry DOI: 10.7270/Q2MW2HZP
					More data for this Ligand-Target Pair
Integrin alpha-3/beta-3 (Homo sapiens (Human))	BDBM50482411 (CHEMBL1208979) Show SMILES Cl.COc1ccc(cc1OC)C(CC(O)=O)NC(=O)CCCC(=O)Nc1ccc2CCNCc2c1 Show InChI InChI=1S/C25H31N3O6.ClH/c1-33-21-9-7-17(13-22(21)34-2)20(14-25(31)32)28-24(30)5-3-4-23(29)27-19-8-6-16-10-11-26-15-18(16)12-19;/h6-9,12-13,20,26H,3-5,10-11,14-15H2,1-2H3,(H,27,29)(H,28,30)(H,31,32);1H	PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	5	n/a	n/a	n/a	n/a	n/a	n/a
A.V. Bogatsky Physico-Chemical Institute of the National Academy of Sciences of Ukraine Curated by ChEMBL					Assay Description Antagonist activity at FITC-tagged alpha3beta3 integrin in human platelet assessed as reduction of ADP-induced platelet aggregation				Bioorg Med Chem Lett 20: 4444-6 (2010) Article DOI: 10.1016/j.bmcl.2010.06.051 BindingDB Entry DOI: 10.7270/Q2H134T5
					More data for this Ligand-Target Pair
Integrin alpha-3/beta-3 (Homo sapiens (Human))	BDBM50482416 (CHEMBL1209862) Show SMILES Cl.OC(=O)CC(NC(=O)CCC(=O)Nc1ccc2CCNCc2c1)c1ccccc1F Show InChI InChI=1S/C22H24FN3O4.ClH/c23-18-4-2-1-3-17(18)19(12-22(29)30)26-21(28)8-7-20(27)25-16-6-5-14-9-10-24-13-15(14)11-16;/h1-6,11,19,24H,7-10,12-13H2,(H,25,27)(H,26,28)(H,29,30);1H	PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	5	n/a	n/a	n/a	n/a	n/a	n/a
A.V. Bogatsky Physico-Chemical Institute of the National Academy of Sciences of Ukraine Curated by ChEMBL					Assay Description Antagonist activity at FITC-tagged alpha3beta3 integrin in human platelet assessed as reduction of ADP-induced platelet aggregation				Bioorg Med Chem Lett 20: 4444-6 (2010) Article DOI: 10.1016/j.bmcl.2010.06.051 BindingDB Entry DOI: 10.7270/Q2H134T5
					More data for this Ligand-Target Pair
Integrin alpha-2/beta-3 (Homo sapiens (Human))	BDBM50370765 (CHEMBL219051) Show SMILES COc1ccc(cc1)C(CC(O)=O)NC(=O)c1cc(cc(c1)[N+]([O-])=O)C(=O)Nc1ccc2CCNCc2c1 Show InChI InChI=1S/C27H26N4O7/c1-38-23-6-3-17(4-7-23)24(14-25(32)33)30-27(35)19-10-18(12-22(13-19)31(36)37)26(34)29-21-5-2-16-8-9-28-15-20(16)11-21/h2-7,10-13,24,28H,8-9,14-15H2,1H3,(H,29,34)(H,30,35)(H,32,33)	PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	5	n/a	n/a	n/a	n/a	n/a	n/a
A.V. Bogatsky Physico-Chemical Institute of the National Academy of Sciences of Ukraine Curated by ChEMBL					Assay Description Displacement of FITC-Fg from integrin alpha2beta3 receptor expressed in human activated platelets				Bioorg Med Chem Lett 16: 5294-7 (2006) Article DOI: 10.1016/j.bmcl.2006.07.090 BindingDB Entry DOI: 10.7270/Q2MW2HZP
					More data for this Ligand-Target Pair
Integrin alpha-2/beta-3 (Homo sapiens (Human))	BDBM50354350 (CHEMBL1836344) Show SMILES OC(=O)CCN1Cc2ccc(NC(=O)CCCC3CCNCC3)cc2C1=O Show InChI InChI=1S/C20H27N3O4/c24-18(3-1-2-14-6-9-21-10-7-14)22-16-5-4-15-13-23(11-8-19(25)26)20(27)17(15)12-16/h4-5,12,14,21H,1-3,6-11,13H2,(H,22,24)(H,25,26)	PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	5.5	n/a	n/a	n/a	n/a	n/a	n/a
A.V. Bogatsky Physico-Chemical Institute of the National Academy of Sciences of Ukraine Curated by ChEMBL					Assay Description Displacement of FITC-labeled fibrinogen from alpha2beta3 in human platelets				Bioorg Med Chem Lett 21: 5971-4 (2011) Article DOI: 10.1016/j.bmcl.2011.07.063 BindingDB Entry DOI: 10.7270/Q26Q1XNS
					More data for this Ligand-Target Pair
Integrin alpha-IIb/beta-3 (Homo sapiens (Human))	BDBM50354350 (CHEMBL1836344) Show SMILES OC(=O)CCN1Cc2ccc(NC(=O)CCCC3CCNCC3)cc2C1=O Show InChI InChI=1S/C20H27N3O4/c24-18(3-1-2-14-6-9-21-10-7-14)22-16-5-4-15-13-23(11-8-19(25)26)20(27)17(15)12-16/h4-5,12,14,21H,1-3,6-11,13H2,(H,22,24)(H,25,26)	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	5.5	n/a	n/a	n/a	n/a	n/a	n/a
A.V. Bogatsky Physico-Chemical Institute of the National Academy of Sciences of Ukraine Curated by ChEMBL					Assay Description Inhibition of FITC-labeled fibrinogen binding to integrin alpha2bbeta3 receptor in human platelets by flow cytometry				Bioorg Med Chem 21: 4646-61 (2013) Article DOI: 10.1016/j.bmc.2013.05.019 BindingDB Entry DOI: 10.7270/Q2Q81FGX
					More data for this Ligand-Target Pair
Integrin alpha-3/beta-3 (Homo sapiens (Human))	BDBM50482401 (CHEMBL1209690) Show SMILES CC(C)Oc1ccc(cc1)C(CC(O)=O)NC(=O)CCC(=O)Nc1ccc2CNCc2c1 Show InChI InChI=1S/C24H29N3O5/c1-15(2)32-20-7-4-16(5-8-20)21(12-24(30)31)27-23(29)10-9-22(28)26-19-6-3-17-13-25-14-18(17)11-19/h3-8,11,15,21,25H,9-10,12-14H2,1-2H3,(H,26,28)(H,27,29)(H,30,31)	PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	6	n/a	n/a	n/a	n/a	n/a	n/a
A.V. Bogatsky Physico-Chemical Institute of the National Academy of Sciences of Ukraine Curated by ChEMBL					Assay Description Antagonist activity at FITC-tagged alpha3beta3 integrin in human platelet assessed as reduction of ADP-induced platelet aggregation				Bioorg Med Chem Lett 20: 4444-6 (2010) Article DOI: 10.1016/j.bmcl.2010.06.051 BindingDB Entry DOI: 10.7270/Q2H134T5
					More data for this Ligand-Target Pair
Integrin alpha-2/beta-3 (Homo sapiens (Human))	BDBM50124560 (CHEMBL3623706) Show SMILES Cl.OC(=O)[C@H](CNC(=O)CCNC(=O)c1ccc2CCNCc2c1)NS(=O)(=O)c1ccccc1 |r| Show InChI InChI=1S/C22H26N4O6S.ClH/c27-20(9-11-24-21(28)16-7-6-15-8-10-23-13-17(15)12-16)25-14-19(22(29)30)26-33(31,32)18-4-2-1-3-5-18;/h1-7,12,19,23,26H,8-11,13-14H2,(H,24,28)(H,25,27)(H,29,30);1H/t19-;/m0./s1	PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	6.20	n/a	n/a	n/a	n/a	n/a	n/a
A.V. Bogatsky Physico-Chemical Institute of National Academy of Sciences of Ukraine Curated by ChEMBL					Assay Description Antagonist activity against integrin alpha2bbeta3 open form in human platelet rich plasma assessed as inhibition of ADP-induced platelet aggregation				J Med Chem 58: 7681-94 (2015) Article DOI: 10.1021/acs.jmedchem.5b00865 BindingDB Entry DOI: 10.7270/Q2QN68MB
					More data for this Ligand-Target Pair
Integrin alpha-2/beta-3 (Homo sapiens (Human))	BDBM50354355 (CHEMBL1836351) Show SMILES CC(CC(O)=O)N1Cc2ccc(NC(=O)c3ccc4CCNCc4c3)cc2C1=O Show InChI InChI=1S/C22H23N3O4/c1-13(8-20(26)27)25-12-16-4-5-18(10-19(16)22(25)29)24-21(28)15-3-2-14-6-7-23-11-17(14)9-15/h2-5,9-10,13,23H,6-8,11-12H2,1H3,(H,24,28)(H,26,27)	PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	6.5	n/a	n/a	n/a	n/a	n/a	n/a
A.V. Bogatsky Physico-Chemical Institute of the National Academy of Sciences of Ukraine Curated by ChEMBL					Assay Description Displacement of FITC-labeled fibrinogen from alpha2beta3 in human platelets				Bioorg Med Chem Lett 21: 5971-4 (2011) Article DOI: 10.1016/j.bmcl.2011.07.063 BindingDB Entry DOI: 10.7270/Q26Q1XNS
					More data for this Ligand-Target Pair
Integrin alpha-IIb/beta-3 (Homo sapiens (Human))	BDBM50354355 (CHEMBL1836351) Show SMILES CC(CC(O)=O)N1Cc2ccc(NC(=O)c3ccc4CCNCc4c3)cc2C1=O Show InChI InChI=1S/C22H23N3O4/c1-13(8-20(26)27)25-12-16-4-5-18(10-19(16)22(25)29)24-21(28)15-3-2-14-6-7-23-11-17(14)9-15/h2-5,9-10,13,23H,6-8,11-12H2,1H3,(H,24,28)(H,26,27)	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	6.5	n/a	n/a	n/a	n/a	n/a	n/a
A.V. Bogatsky Physico-Chemical Institute of the National Academy of Sciences of Ukraine Curated by ChEMBL					Assay Description Inhibition of FITC-labeled fibrinogen binding to integrin alpha2bbeta3 receptor in human platelets by flow cytometry				Bioorg Med Chem 21: 4646-61 (2013) Article DOI: 10.1016/j.bmc.2013.05.019 BindingDB Entry DOI: 10.7270/Q2Q81FGX
					More data for this Ligand-Target Pair
Integrin alpha-IIb/beta-3 (Homo sapiens (Human))	BDBM50354352 (CHEMBL1836347) Show SMILES OC(=O)CCN1Cc2ccc(NC(=O)c3ccc4CCNCc4c3)cc2C1=O Show InChI InChI=1S/C21H21N3O4/c25-19(26)6-8-24-12-15-3-4-17(10-18(15)21(24)28)23-20(27)14-2-1-13-5-7-22-11-16(13)9-14/h1-4,9-10,22H,5-8,11-12H2,(H,23,27)(H,25,26)	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	6.5	n/a	n/a	n/a	n/a	n/a	n/a
A.V. Bogatsky Physico-Chemical Institute of the National Academy of Sciences of Ukraine Curated by ChEMBL					Assay Description Inhibition of FITC-labeled fibrinogen binding to integrin alpha2bbeta3 receptor in human platelets by flow cytometry				Bioorg Med Chem 21: 4646-61 (2013) Article DOI: 10.1016/j.bmc.2013.05.019 BindingDB Entry DOI: 10.7270/Q2Q81FGX
					More data for this Ligand-Target Pair
Integrin alpha-2/beta-3 (Homo sapiens (Human))	BDBM50354352 (CHEMBL1836347) Show SMILES OC(=O)CCN1Cc2ccc(NC(=O)c3ccc4CCNCc4c3)cc2C1=O Show InChI InChI=1S/C21H21N3O4/c25-19(26)6-8-24-12-15-3-4-17(10-18(15)21(24)28)23-20(27)14-2-1-13-5-7-22-11-16(13)9-14/h1-4,9-10,22H,5-8,11-12H2,(H,23,27)(H,25,26)	PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	6.5	n/a	n/a	n/a	n/a	n/a	n/a
A.V. Bogatsky Physico-Chemical Institute of the National Academy of Sciences of Ukraine Curated by ChEMBL					Assay Description Displacement of FITC-labeled fibrinogen from alpha2beta3 in human platelets				Bioorg Med Chem Lett 21: 5971-4 (2011) Article DOI: 10.1016/j.bmcl.2011.07.063 BindingDB Entry DOI: 10.7270/Q26Q1XNS
					More data for this Ligand-Target Pair
Integrin alpha-2/beta-3 (Homo sapiens (Human))	BDBM50354351 (CHEMBL1836345) Show SMILES OC(=O)CCN1Cc2ccc(NC(=O)c3ccc(cc3)C3CCNCC3)cc2C1=O Show InChI InChI=1S/C23H25N3O4/c27-21(28)9-12-26-14-18-5-6-19(13-20(18)23(26)30)25-22(29)17-3-1-15(2-4-17)16-7-10-24-11-8-16/h1-6,13,16,24H,7-12,14H2,(H,25,29)(H,27,28)	PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	6.80	n/a	n/a	n/a	n/a	n/a	n/a
A.V. Bogatsky Physico-Chemical Institute of the National Academy of Sciences of Ukraine Curated by ChEMBL					Assay Description Displacement of FITC-labeled fibrinogen from alpha2beta3 in human platelets				Bioorg Med Chem Lett 21: 5971-4 (2011) Article DOI: 10.1016/j.bmcl.2011.07.063 BindingDB Entry DOI: 10.7270/Q26Q1XNS
					More data for this Ligand-Target Pair
Integrin alpha-IIb/beta-3 (Homo sapiens (Human))	BDBM50354351 (CHEMBL1836345) Show SMILES OC(=O)CCN1Cc2ccc(NC(=O)c3ccc(cc3)C3CCNCC3)cc2C1=O Show InChI InChI=1S/C23H25N3O4/c27-21(28)9-12-26-14-18-5-6-19(13-20(18)23(26)30)25-22(29)17-3-1-15(2-4-17)16-7-10-24-11-8-16/h1-6,13,16,24H,7-12,14H2,(H,25,29)(H,27,28)	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	6.80	n/a	n/a	n/a	n/a	n/a	n/a
A.V. Bogatsky Physico-Chemical Institute of the National Academy of Sciences of Ukraine Curated by ChEMBL					Assay Description Inhibition of FITC-labeled fibrinogen binding to integrin alpha2bbeta3 receptor in human platelets by flow cytometry				Bioorg Med Chem 21: 4646-61 (2013) Article DOI: 10.1016/j.bmc.2013.05.019 BindingDB Entry DOI: 10.7270/Q2Q81FGX
					More data for this Ligand-Target Pair
Integrin alpha-2/beta-3 (Homo sapiens (Human))	BDBM50370769 (CHEMBL218200) Show SMILES OC(=O)CC(NC(=O)c1cc(cc(c1)[N+]([O-])=O)C(=O)Nc1ccc2CCNCc2c1)c1ccccc1 Show InChI InChI=1S/C26H24N4O6/c31-24(32)14-23(17-4-2-1-3-5-17)29-26(34)19-10-18(12-22(13-19)30(35)36)25(33)28-21-7-6-16-8-9-27-15-20(16)11-21/h1-7,10-13,23,27H,8-9,14-15H2,(H,28,33)(H,29,34)(H,31,32)	PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	8	n/a	n/a	n/a	n/a	n/a	n/a
A.V. Bogatsky Physico-Chemical Institute of the National Academy of Sciences of Ukraine Curated by ChEMBL					Assay Description Displacement of FITC-Fg from integrin alpha2beta3 receptor expressed in human activated platelets				Bioorg Med Chem Lett 16: 5294-7 (2006) Article DOI: 10.1016/j.bmcl.2006.07.090 BindingDB Entry DOI: 10.7270/Q2MW2HZP
					More data for this Ligand-Target Pair
Integrin alpha-IIb/beta-3 (Homo sapiens (Human))	BDBM50155250 (3-[3-(2,3-Dihydro-1H-isoindol-5-ylcarbamoyl)-propi...) Show SMILES OC(=O)CC(NC(=O)CCC(=O)Nc1ccc2CNCc2c1)c1ccccc1 Show InChI InChI=1S/C21H23N3O4/c25-19(23-17-7-6-15-12-22-13-16(15)10-17)8-9-20(26)24-18(11-21(27)28)14-4-2-1-3-5-14/h1-7,10,18,22H,8-9,11-13H2,(H,23,25)(H,24,26)(H,27,28)	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	8.30	n/a	n/a	n/a	n/a	n/a	n/a
A.V. Bogatsky Physico-Chemical Institute of the National Academy of Sciences of Ukraine Curated by ChEMBL					Assay Description In vitro inhibition of FITC-labeled fibrinogen binding to alphaIIb-beta3 receptor of human platelets				Bioorg Med Chem Lett 14: 5533-5 (2004) Article DOI: 10.1016/j.bmcl.2004.09.002 BindingDB Entry DOI: 10.7270/Q2J38T9M
					More data for this Ligand-Target Pair
Integrin alpha-3/beta-3 (Homo sapiens (Human))	BDBM50155250 (3-[3-(2,3-Dihydro-1H-isoindol-5-ylcarbamoyl)-propi...) Show SMILES OC(=O)CC(NC(=O)CCC(=O)Nc1ccc2CNCc2c1)c1ccccc1 Show InChI InChI=1S/C21H23N3O4/c25-19(23-17-7-6-15-12-22-13-16(15)10-17)8-9-20(26)24-18(11-21(27)28)14-4-2-1-3-5-14/h1-7,10,18,22H,8-9,11-13H2,(H,23,25)(H,24,26)(H,27,28)	PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	8.30	n/a	n/a	n/a	n/a	n/a	n/a
A.V. Bogatsky Physico-Chemical Institute of the National Academy of Sciences of Ukraine Curated by ChEMBL					Assay Description Antagonist activity at FITC-tagged alpha3beta3 integrin in human platelet assessed as reduction of ADP-induced platelet aggregation				Bioorg Med Chem Lett 20: 4444-6 (2010) Article DOI: 10.1016/j.bmcl.2010.06.051 BindingDB Entry DOI: 10.7270/Q2H134T5
					More data for this Ligand-Target Pair
Integrin alpha-3/beta-3 (Homo sapiens (Human))	BDBM50482404 (CHEMBL1209860) Show SMILES Cl.OC(=O)CC(NC(=O)CCC(=O)Nc1ccc2CCNCc2c1)c1ccc(F)cc1 Show InChI InChI=1S/C22H24FN3O4.ClH/c23-17-4-1-15(2-5-17)19(12-22(29)30)26-21(28)8-7-20(27)25-18-6-3-14-9-10-24-13-16(14)11-18;/h1-6,11,19,24H,7-10,12-13H2,(H,25,27)(H,26,28)(H,29,30);1H	PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	8.90	n/a	n/a	n/a	n/a	n/a	n/a
A.V. Bogatsky Physico-Chemical Institute of the National Academy of Sciences of Ukraine Curated by ChEMBL					Assay Description Antagonist activity at FITC-tagged alpha3beta3 integrin in human platelet rich plasma				Bioorg Med Chem Lett 20: 4444-6 (2010) Article DOI: 10.1016/j.bmcl.2010.06.051 BindingDB Entry DOI: 10.7270/Q2H134T5
					More data for this Ligand-Target Pair
Integrin alpha-3/beta-3 (Homo sapiens (Human))	BDBM50482413 (CHEMBL1209691) Show SMILES COc1ccc(cc1OC)C(CC(O)=O)NC(=O)CCC(=O)Nc1ccc2CNCc2c1 Show InChI InChI=1S/C23H27N3O6/c1-31-19-6-4-14(10-20(19)32-2)18(11-23(29)30)26-22(28)8-7-21(27)25-17-5-3-15-12-24-13-16(15)9-17/h3-6,9-10,18,24H,7-8,11-13H2,1-2H3,(H,25,27)(H,26,28)(H,29,30)	PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	9	n/a	n/a	n/a	n/a	n/a	n/a
A.V. Bogatsky Physico-Chemical Institute of the National Academy of Sciences of Ukraine Curated by ChEMBL					Assay Description Antagonist activity at FITC-tagged alpha3beta3 integrin in human platelet assessed as reduction of ADP-induced platelet aggregation				Bioorg Med Chem Lett 20: 4444-6 (2010) Article DOI: 10.1016/j.bmcl.2010.06.051 BindingDB Entry DOI: 10.7270/Q2H134T5
					More data for this Ligand-Target Pair
Integrin alpha-2/beta-3 (Homo sapiens (Human))	BDBM50370768 (CHEMBL219603) Show SMILES OC(=O)CCNC(=O)c1cccc(c1)C(=O)Nc1ccc2CCNCc2c1 Show InChI InChI=1S/C20H21N3O4/c24-18(25)7-9-22-19(26)14-2-1-3-15(10-14)20(27)23-17-5-4-13-6-8-21-12-16(13)11-17/h1-5,10-11,21H,6-9,12H2,(H,22,26)(H,23,27)(H,24,25)	PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	9	n/a	n/a	n/a	n/a	n/a	n/a
A.V. Bogatsky Physico-Chemical Institute of the National Academy of Sciences of Ukraine Curated by ChEMBL					Assay Description Displacement of FITC-Fg from integrin alpha2beta3 receptor expressed in human activated platelets				Bioorg Med Chem Lett 16: 5294-7 (2006) Article DOI: 10.1016/j.bmcl.2006.07.090 BindingDB Entry DOI: 10.7270/Q2MW2HZP
					More data for this Ligand-Target Pair
Integrin alpha-IIb/beta-3 (Homo sapiens (Human))	BDBM50155251 (3-[3-(2,3-Dihydro-1H-isoindol-5-ylcarbamoyl)-propi...) Show SMILES OC(=O)CCNC(=O)CCC(=O)Nc1ccc2CNCc2c1 Show InChI InChI=1S/C15H19N3O4/c19-13(17-6-5-15(21)22)3-4-14(20)18-12-2-1-10-8-16-9-11(10)7-12/h1-2,7,16H,3-6,8-9H2,(H,17,19)(H,18,20)(H,21,22)	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	10	n/a	n/a	n/a	n/a	n/a	n/a
A.V. Bogatsky Physico-Chemical Institute of the National Academy of Sciences of Ukraine Curated by ChEMBL					Assay Description In vitro inhibition of FITC-labeled fibrinogen binding to alphaIIb-beta3 receptor of human platelets				Bioorg Med Chem Lett 14: 5533-5 (2004) Article DOI: 10.1016/j.bmcl.2004.09.002 BindingDB Entry DOI: 10.7270/Q2J38T9M
					More data for this Ligand-Target Pair
Integrin alpha-2/beta-3 (Homo sapiens (Human))	BDBM50124522 (CHEMBL3623709) Show SMILES Cl.Cl.NCCCC(=O)Nc1ccc2nc([nH]c(=O)c2c1)N1CCNCC1 Show InChI InChI=1S/C16H22N6O2.2ClH/c17-5-1-2-14(23)19-11-3-4-13-12(10-11)15(24)21-16(20-13)22-8-6-18-7-9-22;;/h3-4,10,18H,1-2,5-9,17H2,(H,19,23)(H,20,21,24);2*1H	PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	11	n/a	n/a	n/a	n/a	n/a	n/a
A.V. Bogatsky Physico-Chemical Institute of National Academy of Sciences of Ukraine Curated by ChEMBL					Assay Description Antagonist activity against integrin alpha2bbeta3 closed form in human platelet rich plasma assessed as inhibition of ADP-induced platelet aggregatio...				J Med Chem 58: 7681-94 (2015) Article DOI: 10.1021/acs.jmedchem.5b00865 BindingDB Entry DOI: 10.7270/Q2QN68MB
					More data for this Ligand-Target Pair
Integrin alpha-3/beta-3 (Homo sapiens (Human))	BDBM50323320 (3-(3,4-dimethoxyphenyl)-3-(3-(1,2,3,4-tetrahydrois...) Show SMILES COc1ccc(cc1OC)C(CC(O)=O)NC(=O)c1cccc(c1)C(=O)Nc1ccc2CCNCc2c1 Show InChI InChI=1S/C28H29N3O6/c1-36-24-9-7-18(14-25(24)37-2)23(15-26(32)33)31-28(35)20-5-3-4-19(12-20)27(34)30-22-8-6-17-10-11-29-16-21(17)13-22/h3-9,12-14,23,29H,10-11,15-16H2,1-2H3,(H,30,34)(H,31,35)(H,32,33)	PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	12	n/a	n/a	n/a	n/a	n/a	n/a
A.V. Bogatsky Physico-Chemical Institute of the National Academy of Sciences of Ukraine Curated by ChEMBL					Assay Description Antagonist activity at FITC-tagged alpha3beta3 integrin in human platelet rich plasma				Bioorg Med Chem Lett 20: 4444-6 (2010) Article DOI: 10.1016/j.bmcl.2010.06.051 BindingDB Entry DOI: 10.7270/Q2H134T5
					More data for this Ligand-Target Pair
Integrin alpha-3/beta-3 (Homo sapiens (Human))	BDBM50482403 (CHEMBL1209774) Show SMILES Cl.OC(=O)CC(NC(=O)CCC(=O)Nc1ccc2CCNCc2c1)c1ccccc1 Show InChI InChI=1S/C22H25N3O4.ClH/c26-20(24-18-7-6-15-10-11-23-14-17(15)12-18)8-9-21(27)25-19(13-22(28)29)16-4-2-1-3-5-16;/h1-7,12,19,23H,8-11,13-14H2,(H,24,26)(H,25,27)(H,28,29);1H	PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	13	n/a	n/a	n/a	n/a	n/a	n/a
A.V. Bogatsky Physico-Chemical Institute of the National Academy of Sciences of Ukraine Curated by ChEMBL					Assay Description Antagonist activity at FITC-tagged alpha3beta3 integrin in human platelet rich plasma				Bioorg Med Chem Lett 20: 4444-6 (2010) Article DOI: 10.1016/j.bmcl.2010.06.051 BindingDB Entry DOI: 10.7270/Q2H134T5
					More data for this Ligand-Target Pair
Integrin alpha-3/beta-3 (Homo sapiens (Human))	BDBM50323319 (3-(3-(carbamoyl)benzamido)-3-(4-methoxyphenyl)prop...) Show SMILES COc1ccc(cc1)C(CC(O)=O)NC(=O)c1cccc(c1)C(=O)Nc1ccc2CCNCc2c1 Show InChI InChI=1S/C27H27N3O5/c1-35-23-9-6-18(7-10-23)24(15-25(31)32)30-27(34)20-4-2-3-19(13-20)26(33)29-22-8-5-17-11-12-28-16-21(17)14-22/h2-10,13-14,24,28H,11-12,15-16H2,1H3,(H,29,33)(H,30,34)(H,31,32)	PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	17	n/a	n/a	n/a	n/a	n/a	n/a
A.V. Bogatsky Physico-Chemical Institute of the National Academy of Sciences of Ukraine Curated by ChEMBL					Assay Description Antagonist activity at FITC-tagged alpha3beta3 integrin in human platelet rich plasma				Bioorg Med Chem Lett 20: 4444-6 (2010) Article DOI: 10.1016/j.bmcl.2010.06.051 BindingDB Entry DOI: 10.7270/Q2H134T5
					More data for this Ligand-Target Pair
Integrin alpha-3/beta-3 (Homo sapiens (Human))	BDBM50482410 (CHEMBL1208914) Show SMILES Cl.COc1ccc(cc1)C(CC(O)=O)NC(=O)CCCC(=O)Nc1ccc2CCNCc2c1 Show InChI InChI=1S/C24H29N3O5.ClH/c1-32-20-9-6-17(7-10-20)21(14-24(30)31)27-23(29)4-2-3-22(28)26-19-8-5-16-11-12-25-15-18(16)13-19;/h5-10,13,21,25H,2-4,11-12,14-15H2,1H3,(H,26,28)(H,27,29)(H,30,31);1H	PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	18	n/a	n/a	n/a	n/a	n/a	n/a
A.V. Bogatsky Physico-Chemical Institute of the National Academy of Sciences of Ukraine Curated by ChEMBL					Assay Description Antagonist activity at FITC-tagged alpha3beta3 integrin in human platelet assessed as reduction of ADP-induced platelet aggregation				Bioorg Med Chem Lett 20: 4444-6 (2010) Article DOI: 10.1016/j.bmcl.2010.06.051 BindingDB Entry DOI: 10.7270/Q2H134T5
					More data for this Ligand-Target Pair
Integrin alpha-IIb/beta-3 (Homo sapiens (Human))	BDBM50156362 (CHEMBL3785983) Show SMILES Cl.Cl.O=C(Nc1ccc2nc([nH]c(=O)c2c1)N1CCNCC1)c1ccc(cc1)N1CCNCC1 Show InChI InChI=1S/C23H27N7O2.2ClH/c31-21(16-1-4-18(5-2-16)29-11-7-24-8-12-29)26-17-3-6-20-19(15-17)22(32)28-23(27-20)30-13-9-25-10-14-30;;/h1-6,15,24-25H,7-14H2,(H,26,31)(H,27,28,32);2*1H	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	20	n/a	n/a	n/a	n/a	n/a	n/a
A.V. Bogatsky Physico-Chemical Institute of the National Academy of Sciences of Ukraine Curated by ChEMBL					Assay Description Inhibition of FITC-labelled fibrinogen binding to integrin alpha2b beta3 receptor in human platelet cells				Bioorg Med Chem Lett 26: 1839-43 (2016) Article DOI: 10.1016/j.bmcl.2016.02.011 BindingDB Entry DOI: 10.7270/Q2NV9M57
					More data for this Ligand-Target Pair

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