Compile Data Set for Download or QSAR

Found 5 hits with Last Name = 'annereau' and Initial = 'jp'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
DNA topoisomerase 1 (Homo sapiens (Human))	BDBM50372625 (CHEMBL406538) Show SMILES NCCc1c([nH]c2cc(Br)ccc12)C(c1c[nH]c2ccccc12)c1[nH]c2cc(Br)ccc2c1CCNC(=O)C(F)(F)F |w:13.26| Show InChI InChI=1S/C31H26Br2F3N5O/c32-16-5-7-19-21(9-11-37)28(40-25(19)13-16)27(23-15-39-24-4-2-1-3-18(23)24)29-22(10-12-38-30(42)31(34,35)36)20-8-6-17(33)14-26(20)41-29/h1-8,13-15,27,39-41H,9-12,37H2,(H,38,42)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	8.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ de Paris-sud 11 Curated by ChEMBL					Assay Description Inhibition of topoisomerase 1-mediated DNA relaxation				Bioorg Med Chem Lett 18: 1212-6 (2008) Article DOI: 10.1016/j.bmcl.2007.11.113 BindingDB Entry DOI: 10.7270/Q2NV9K2G
					More data for this Ligand-Target Pair
DNA topoisomerase 1 (Homo sapiens (Human))	BDBM50372627 (CHEMBL406537) Show SMILES NCCc1c([nH]c2cc(Br)ccc12)C(c1cn(c2ccccc12)S(=O)(=O)c1ccccc1)c1[nH]c2cc(Br)ccc2c1CCNC(=O)C(F)(F)F |w:13.36| Show InChI InChI=1S/C37H30Br2F3N5O3S/c38-21-10-12-24-27(14-16-43)34(45-30(24)18-21)33(29-20-47(32-9-5-4-8-26(29)32)51(49,50)23-6-2-1-3-7-23)35-28(15-17-44-36(48)37(40,41)42)25-13-11-22(39)19-31(25)46-35/h1-13,18-20,33,45-46H,14-17,43H2,(H,44,48)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	9.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ de Paris-sud 11 Curated by ChEMBL					Assay Description Inhibition of topoisomerase 1-mediated DNA relaxation				Bioorg Med Chem Lett 18: 1212-6 (2008) Article DOI: 10.1016/j.bmcl.2007.11.113 BindingDB Entry DOI: 10.7270/Q2NV9K2G
					More data for this Ligand-Target Pair
DNA topoisomerase 2-alpha (Homo sapiens (Human))	BDBM50372625 (CHEMBL406538) Show SMILES NCCc1c([nH]c2cc(Br)ccc12)C(c1c[nH]c2ccccc12)c1[nH]c2cc(Br)ccc2c1CCNC(=O)C(F)(F)F |w:13.26| Show InChI InChI=1S/C31H26Br2F3N5O/c32-16-5-7-19-21(9-11-37)28(40-25(19)13-16)27(23-15-39-24-4-2-1-3-18(23)24)29-22(10-12-38-30(42)31(34,35)36)20-8-6-17(33)14-26(20)41-29/h1-8,13-15,27,39-41H,9-12,37H2,(H,38,42)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.30E+4	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ de Paris-sud 11 Curated by ChEMBL					Assay Description Inhibition of topoisomerase 2 meadiated DNA relaxation				Bioorg Med Chem Lett 18: 1212-6 (2008) Article DOI: 10.1016/j.bmcl.2007.11.113 BindingDB Entry DOI: 10.7270/Q2NV9K2G
					More data for this Ligand-Target Pair
DNA topoisomerase 2-alpha (Homo sapiens (Human))	BDBM50372627 (CHEMBL406537) Show SMILES NCCc1c([nH]c2cc(Br)ccc12)C(c1cn(c2ccccc12)S(=O)(=O)c1ccccc1)c1[nH]c2cc(Br)ccc2c1CCNC(=O)C(F)(F)F |w:13.36| Show InChI InChI=1S/C37H30Br2F3N5O3S/c38-21-10-12-24-27(14-16-43)34(45-30(24)18-21)33(29-20-47(32-9-5-4-8-26(29)32)51(49,50)23-6-2-1-3-7-23)35-28(15-17-44-36(48)37(40,41)42)25-13-11-22(39)19-31(25)46-35/h1-13,18-20,33,45-46H,14-17,43H2,(H,44,48)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.90E+4	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ de Paris-sud 11 Curated by ChEMBL					Assay Description Inhibition of topoisomerase 2 meadiated DNA relaxation				Bioorg Med Chem Lett 18: 1212-6 (2008) Article DOI: 10.1016/j.bmcl.2007.11.113 BindingDB Entry DOI: 10.7270/Q2NV9K2G
					More data for this Ligand-Target Pair
DNA topoisomerase 2-alpha (Homo sapiens (Human))	BDBM50372626 (BENGACARBOLINE) Show SMILES NCCc1c([nH]c2ccccc12)C1(NCCc2c1[nH]c1ccccc21)c1c[nH]c2ccccc12 |w:12.29| Show InChI InChI=1S/C29H27N5/c30-15-13-20-18-7-1-5-11-25(18)33-27(20)29(23-17-31-24-10-4-3-9-22(23)24)28-21(14-16-32-29)19-8-2-6-12-26(19)34-28/h1-12,17,31-34H,13-16,30H2	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ de Paris-sud 11 Curated by ChEMBL					Assay Description Inhibition of topoisomerase 2 meadiated DNA relaxation				Bioorg Med Chem Lett 18: 1212-6 (2008) Article DOI: 10.1016/j.bmcl.2007.11.113 BindingDB Entry DOI: 10.7270/Q2NV9K2G
					More data for this Ligand-Target Pair