Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Prostaglandin G/H synthase 2 (Homo sapiens (Human)) | BDBM50150726 (3-(4-Methanesulfonyl-phenyl)-6-(4-methoxy-phenyl)-...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 20 | n/a | n/a | n/a | n/a | n/a | n/a |
Central Drug Research Institute Curated by ChEMBL | Assay Description Inhibition of COX2 (unknown origin) | Bioorg Med Chem 17: 3847-56 (2009) Article DOI: 10.1016/j.bmc.2009.04.032 BindingDB Entry DOI: 10.7270/Q2R2118H | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
DNA ligase 1 (Homo sapiens (Human)) | BDBM50431467 (CHEMBL2348305) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL MCE MMDB PC cid PC sid PDB UniChem Similars | Article PubMed | n/a | n/a | 1.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Allahabad Curated by ChEMBL | Assay Description Inhibition of human DNA ligase 1 | Eur J Med Chem 182: (2019) Article DOI: 10.1016/j.ejmech.2019.111657 BindingDB Entry DOI: 10.7270/Q2RN3C6C | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
DNA ligase 4 (Homo sapiens) | BDBM50509110 (CHEMBL4458668) | PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | Purchase MCE PC cid PC sid UniChem | Article PubMed | n/a | n/a | 5.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Allahabad Curated by ChEMBL | Assay Description Competitive inhibition of human DNA ligase 4 using nicked DNA as substrate by high-throughput fluorescence energy transfer-based DNA joining assay | Eur J Med Chem 182: (2019) Article DOI: 10.1016/j.ejmech.2019.111657 BindingDB Entry DOI: 10.7270/Q2RN3C6C | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
DNA ligase 1 (Homo sapiens (Human)) | BDBM50509110 (CHEMBL4458668) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase MCE PC cid PC sid UniChem | Article PubMed | n/a | n/a | 5.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Allahabad Curated by ChEMBL | Assay Description Competitive inhibition of human DNA ligase 1 using nicked DNA as substrate by high-throughput fluorescence energy transfer-based DNA joining assay | Eur J Med Chem 182: (2019) Article DOI: 10.1016/j.ejmech.2019.111657 BindingDB Entry DOI: 10.7270/Q2RN3C6C | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Protein S100-B (Rattus norvegicus) | BDBM50146593 (CHEMBL3764851) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 6.70E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Maryland Curated by ChEMBL | Assay Description Displacement of TAMRA-TRTK12 from recombinant rat calcium loaded S100-B by fluorescence polarization competition assay | J Med Chem 59: 592-608 (2016) Article DOI: 10.1021/acs.jmedchem.5b01369 BindingDB Entry DOI: 10.7270/Q2TH8PJQ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
DNA ligase 3 (Homo sapiens) | BDBM50509110 (CHEMBL4458668) | PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | Purchase MCE PC cid PC sid UniChem | Article PubMed | n/a | n/a | 9.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Allahabad Curated by ChEMBL | Assay Description Competitive inhibition of human DNA ligase 3 using nicked DNA as substrate by high-throughput fluorescence energy transfer-based DNA joining assay | Eur J Med Chem 182: (2019) Article DOI: 10.1016/j.ejmech.2019.111657 BindingDB Entry DOI: 10.7270/Q2RN3C6C | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
DNA ligase 1 (Homo sapiens (Human)) | BDBM50509109 (CHEMBL4461698) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase MCE PC cid PC sid UniChem | Article PubMed | n/a | n/a | 1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Allahabad Curated by ChEMBL | Assay Description Competitive inhibition of human DNA ligase 1 using nicked DNA as substrate by high-throughput fluorescence energy transfer-based DNA joining assay | Eur J Med Chem 182: (2019) Article DOI: 10.1016/j.ejmech.2019.111657 BindingDB Entry DOI: 10.7270/Q2RN3C6C | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
DNA ligase 3 (Homo sapiens) | BDBM50509109 (CHEMBL4461698) | PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | Purchase MCE PC cid PC sid UniChem | Article PubMed | n/a | n/a | 1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Allahabad Curated by ChEMBL | Assay Description Competitive inhibition of human DNA ligase 3 using nicked DNA as substrate by high-throughput fluorescence energy transfer-based DNA joining assay | Eur J Med Chem 182: (2019) Article DOI: 10.1016/j.ejmech.2019.111657 BindingDB Entry DOI: 10.7270/Q2RN3C6C | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
DNA ligase 1 (Homo sapiens (Human)) | BDBM50509111 (CHEMBL4468667) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase MCE PC cid PC sid UniChem | Article PubMed | n/a | n/a | 1.20E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Allahabad Curated by ChEMBL | Assay Description Uncompetitive inhibition of human DNA ligase 1 using nicked DNA as substrate by high-throughput fluorescence energy transfer-based DNA joining assay | Eur J Med Chem 182: (2019) Article DOI: 10.1016/j.ejmech.2019.111657 BindingDB Entry DOI: 10.7270/Q2RN3C6C | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
DNA ligase 1 (Homo sapiens (Human)) | BDBM50509117 (CHEMBL4554752) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 1.39E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Allahabad Curated by ChEMBL | Assay Description Inhibition of human DNA ligase 1 expressed in Escherichia coli BL21 (DE3) cells using nicked DNA as substrate preincubated for 30 mins followed by su... | Eur J Med Chem 182: (2019) Article DOI: 10.1016/j.ejmech.2019.111657 BindingDB Entry DOI: 10.7270/Q2RN3C6C | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
DNA ligase 1 (Homo sapiens (Human)) | BDBM50509115 (CHEMBL4556388) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 1.41E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Allahabad Curated by ChEMBL | Assay Description Inhibition of human DNA ligase 1 expressed in Escherichia coli BL21 (DE3) cells using nicked DNA as substrate preincubated for 30 mins followed by su... | Eur J Med Chem 182: (2019) Article DOI: 10.1016/j.ejmech.2019.111657 BindingDB Entry DOI: 10.7270/Q2RN3C6C | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
DNA ligase 1 (Homo sapiens (Human)) | BDBM50509114 (CHEMBL4453581) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 1.41E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Allahabad Curated by ChEMBL | Assay Description Inhibition of human DNA ligase 1 expressed in Escherichia coli BL21 (DE3) cells using nicked DNA as substrate preincubated for 30 mins followed by su... | Eur J Med Chem 182: (2019) Article DOI: 10.1016/j.ejmech.2019.111657 BindingDB Entry DOI: 10.7270/Q2RN3C6C | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
DNA ligase 1 (Homo sapiens (Human)) | BDBM50509119 (CHEMBL4532660) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 1.41E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Allahabad Curated by ChEMBL | Assay Description Inhibition of human DNA ligase 1 expressed in Escherichia coli BL21 (DE3) cells using nicked DNA as substrate preincubated for 30 mins followed by su... | Eur J Med Chem 182: (2019) Article DOI: 10.1016/j.ejmech.2019.111657 BindingDB Entry DOI: 10.7270/Q2RN3C6C | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
DNA ligase 1 (Homo sapiens (Human)) | BDBM50509108 (CHEMBL4440472) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 1.55E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Allahabad Curated by ChEMBL | Assay Description Inhibition of human DNA ligase 1 expressed in Escherichia coli BL21 (DE3) cells using nicked DNA as substrate preincubated for 30 mins followed by su... | Eur J Med Chem 182: (2019) Article DOI: 10.1016/j.ejmech.2019.111657 BindingDB Entry DOI: 10.7270/Q2RN3C6C | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
DNA ligase 1 (Homo sapiens (Human)) | BDBM50509118 (CHEMBL4577708) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 1.58E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Allahabad Curated by ChEMBL | Assay Description Inhibition of human DNA ligase 1 using 52-mer DNA/25-mer DNA/27-mer DNA as substrate | Eur J Med Chem 182: (2019) Article DOI: 10.1016/j.ejmech.2019.111657 BindingDB Entry DOI: 10.7270/Q2RN3C6C | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Protein S100-B (Rattus norvegicus) | BDBM50146592 (CHEMBL3764285) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 1.83E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Maryland Curated by ChEMBL | Assay Description Displacement of TAMRA-TRTK12 from recombinant rat calcium loaded S100-B by fluorescence polarization competition assay | J Med Chem 59: 592-608 (2016) Article DOI: 10.1021/acs.jmedchem.5b01369 BindingDB Entry DOI: 10.7270/Q2TH8PJQ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
DNA ligase 1 (Homo sapiens (Human)) | BDBM50509116 ((+/-)-Protolichesterinic acid) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 1.84E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Allahabad Curated by ChEMBL | Assay Description Inhibition of human DNA ligase 1 using 52-mer DNA/25-mer DNA/27-mer DNA as substrate by fluorescence assay | Eur J Med Chem 182: (2019) Article DOI: 10.1016/j.ejmech.2019.111657 BindingDB Entry DOI: 10.7270/Q2RN3C6C | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
DNA ligase 1 (Homo sapiens (Human)) | BDBM50509120 (CHEMBL4464745) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 2.11E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Allahabad Curated by ChEMBL | Assay Description Inhibition of human DNA ligase 1 expressed in Escherichia coli BL21 (DE3) cells using nicked DNA as substrate preincubated for 30 mins followed by su... | Eur J Med Chem 182: (2019) Article DOI: 10.1016/j.ejmech.2019.111657 BindingDB Entry DOI: 10.7270/Q2RN3C6C | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
DNA ligase 1 (Homo sapiens (Human)) | BDBM50509112 (CHEMBL4456837) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 2.31E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Allahabad Curated by ChEMBL | Assay Description Inhibition of human DNA ligase 1 using 52-mer DNA/25-mer DNA/27-mer DNA as substrate | Eur J Med Chem 182: (2019) Article DOI: 10.1016/j.ejmech.2019.111657 BindingDB Entry DOI: 10.7270/Q2RN3C6C | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
DNA ligase 1 (Homo sapiens (Human)) | BDBM50478514 (Fagaronine | Fagaronine Chloride) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 2.59E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Allahabad Curated by ChEMBL | Assay Description Inhibition of human DNA ligase 1 using 52-mer DNA/25-mer DNA/27-mer DNA as substrate by fluorescence assay | Eur J Med Chem 182: (2019) Article DOI: 10.1016/j.ejmech.2019.111657 BindingDB Entry DOI: 10.7270/Q2RN3C6C | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
DNA ligase 1 (Homo sapiens (Human)) | BDBM50509113 (CHEMBL4465196) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 2.65E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Allahabad Curated by ChEMBL | Assay Description Inhibition of human DNA ligase 1 expressed in Escherichia coli BL21 (DE3) cells using nicked DNA as substrate preincubated for 30 mins followed by su... | Eur J Med Chem 182: (2019) Article DOI: 10.1016/j.ejmech.2019.111657 BindingDB Entry DOI: 10.7270/Q2RN3C6C | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
DNA ligase 1 (Homo sapiens (Human)) | BDBM50509122 (CHEMBL4541795) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 3.64E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Allahabad Curated by ChEMBL | Assay Description Inhibition of human DNA ligase 1 expressed in Escherichia coli BL21 (DE3) cells using nicked DNA as substrate preincubated for 30 mins followed by su... | Eur J Med Chem 182: (2019) Article DOI: 10.1016/j.ejmech.2019.111657 BindingDB Entry DOI: 10.7270/Q2RN3C6C | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Protein S100-B (Rattus norvegicus) | BDBM50146595 (CHEMBL3765382) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 5.11E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Maryland Curated by ChEMBL | Assay Description Displacement of TAMRA-TRTK12 from recombinant rat calcium loaded S100-B by fluorescence polarization competition assay | J Med Chem 59: 592-608 (2016) Article DOI: 10.1021/acs.jmedchem.5b01369 BindingDB Entry DOI: 10.7270/Q2TH8PJQ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Protein S100-B (Rattus norvegicus) | BDBM50100895 (2-(4-(4-carbamimidoylphenoxy)phenyl)-1H-indole-6-c...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid PDB UniChem Patents Similars | PDB Article PubMed | n/a | n/a | 6.66E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Maryland Curated by ChEMBL | Assay Description Displacement of TAMRA-TRTK12 from recombinant rat calcium loaded S100-B by fluorescence polarization competition assay | J Med Chem 59: 592-608 (2016) Article DOI: 10.1021/acs.jmedchem.5b01369 BindingDB Entry DOI: 10.7270/Q2TH8PJQ | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (crystal) | ||||||||||||
DNA ligase 1 (Homo sapiens (Human)) | BDBM50017566 (CHEBI:7578 | NITIDINE) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase MCE KEGG PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 7.17E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Allahabad Curated by ChEMBL | Assay Description Inhibition of human DNA ligase 1 using 52-mer DNA/25-mer DNA/27-mer DNA as substrate by fluorescence assay | Eur J Med Chem 182: (2019) Article DOI: 10.1016/j.ejmech.2019.111657 BindingDB Entry DOI: 10.7270/Q2RN3C6C | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
DNA ligase 1 (Homo sapiens (Human)) | BDBM15236 (3,5,7-trihydroxy-2-(3,4,5-trihydroxyphenyl)-4H-chr...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars | Article PubMed | n/a | n/a | 8.79E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Allahabad Curated by ChEMBL | Assay Description Inhibition of human DNA ligase 1 using 52-mer DNA/25-mer DNA/27-mer DNA as substrate by fluorescence assay | Eur J Med Chem 182: (2019) Article DOI: 10.1016/j.ejmech.2019.111657 BindingDB Entry DOI: 10.7270/Q2RN3C6C | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
DNA ligase 1 (Homo sapiens (Human)) | BDBM50346601 (NSC-114945 | OLEANOLIC_ACID | Oleanolic acid | Ole...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase MCE KEGG PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 1.86E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Allahabad Curated by ChEMBL | Assay Description Inhibition of human DNA ligase 1 using 52-mer DNA/25-mer DNA/27-mer DNA as substrate by fluorescence assay | Eur J Med Chem 182: (2019) Article DOI: 10.1016/j.ejmech.2019.111657 BindingDB Entry DOI: 10.7270/Q2RN3C6C | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
DNA ligase 1 (Homo sapiens (Human)) | BDBM50509121 (CHEMBL4586295) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 1.95E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Allahabad Curated by ChEMBL | Assay Description Inhibition of human DNA ligase 1 using 52-mer DNA/25-mer DNA/27-mer DNA as substrate by fluorescence assay | Eur J Med Chem 182: (2019) Article DOI: 10.1016/j.ejmech.2019.111657 BindingDB Entry DOI: 10.7270/Q2RN3C6C | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
DNA ligase 1 (Homo sapiens (Human)) | BDBM50478515 (Aleuritolic Acid | CHEBI:73107 | Maprounic Acid) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 2.08E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Allahabad Curated by ChEMBL | Assay Description Inhibition of human DNA ligase 1 using 52-mer DNA/25-mer DNA/27-mer DNA as substrate by fluorescence assay | Eur J Med Chem 182: (2019) Article DOI: 10.1016/j.ejmech.2019.111657 BindingDB Entry DOI: 10.7270/Q2RN3C6C | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
DNA ligase 1 (Homo sapiens (Human)) | BDBM26658 (2-(2,4-dihydroxyphenyl)-3,5,7-trihydroxy-1-benzopy...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL MCE KEGG PC cid PC sid PDB UniChem Patents Similars | Article PubMed | n/a | n/a | 2.24E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Allahabad Curated by ChEMBL | Assay Description Inhibition of human DNA ligase 1 using 52-mer DNA/25-mer DNA/27-mer DNA as substrate by fluorescence assay | Eur J Med Chem 182: (2019) Article DOI: 10.1016/j.ejmech.2019.111657 BindingDB Entry DOI: 10.7270/Q2RN3C6C | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
DNA ligase 1 (Homo sapiens (Human)) | BDBM50148911 ((3beta)-3-hydroxyurs-12-en-28-oic acid | 3beta-hyd...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL MCE KEGG PC cid PC sid PDB UniChem Patents Similars | Article PubMed | n/a | n/a | 2.62E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Allahabad Curated by ChEMBL | Assay Description Inhibition of human DNA ligase 1 using 52-mer DNA/25-mer DNA/27-mer DNA as substrate by fluorescence assay | Eur J Med Chem 182: (2019) Article DOI: 10.1016/j.ejmech.2019.111657 BindingDB Entry DOI: 10.7270/Q2RN3C6C | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
DNA ligase 1 (Homo sapiens (Human)) | BDBM50480323 (CHEBI:5188 | Fulvoplumierin) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase KEGG PC cid PC sid UniChem | Article PubMed | n/a | n/a | 3.56E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Allahabad Curated by ChEMBL | Assay Description Inhibition of human DNA ligase 1 using 52-mer DNA/25-mer DNA/27-mer DNA as substrate by fluorescence assay | Eur J Med Chem 182: (2019) Article DOI: 10.1016/j.ejmech.2019.111657 BindingDB Entry DOI: 10.7270/Q2RN3C6C | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
DNA ligase 1 (Homo sapiens (Human)) | BDBM25525 (24-methyl-5,7,18,20-tetraoxa-24-azahexacyclo[11.11...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars | Article PubMed | n/a | n/a | 3.82E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Allahabad Curated by ChEMBL | Assay Description Inhibition of human DNA ligase 1 using 52-mer DNA/25-mer DNA/27-mer DNA as substrate by fluorescence assay | Eur J Med Chem 182: (2019) Article DOI: 10.1016/j.ejmech.2019.111657 BindingDB Entry DOI: 10.7270/Q2RN3C6C | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Protein S100-B (Rattus norvegicus) | BDBM50146596 (CHEMBL3765054) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 9.82E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Maryland Curated by ChEMBL | Assay Description Displacement of TAMRA-TRTK12 from recombinant rat calcium loaded S100-B by fluorescence polarization competition assay | J Med Chem 59: 592-608 (2016) Article DOI: 10.1021/acs.jmedchem.5b01369 BindingDB Entry DOI: 10.7270/Q2TH8PJQ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Protein S100-B (Rattus norvegicus) | BDBM50146594 (CHEMBL3765771) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 2.22E+6 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Maryland Curated by ChEMBL | Assay Description Displacement of TAMRA-TRTK12 from recombinant rat calcium loaded S100-B by fluorescence polarization competition assay | J Med Chem 59: 592-608 (2016) Article DOI: 10.1021/acs.jmedchem.5b01369 BindingDB Entry DOI: 10.7270/Q2TH8PJQ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Protein S100-B (Rattus norvegicus) | BDBM50146596 (CHEMBL3765054) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | 8.95E+4 | n/a | n/a | n/a | n/a | n/a |
University of Maryland Curated by ChEMBL | Assay Description Displacement of TAMRA-TRTK12 from recombinant rat calcium loaded S100-B by Nikolovska-Cleska analysis | J Med Chem 59: 592-608 (2016) Article DOI: 10.1021/acs.jmedchem.5b01369 BindingDB Entry DOI: 10.7270/Q2TH8PJQ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Protein S100-B (Rattus norvegicus) | BDBM50146592 (CHEMBL3764285) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | 1.60E+3 | n/a | n/a | n/a | n/a | n/a |
University of Maryland Curated by ChEMBL | Assay Description Displacement of TAMRA-TRTK12 from recombinant rat calcium loaded S100-B by Nikolovska-Cleska analysis | J Med Chem 59: 592-608 (2016) Article DOI: 10.1021/acs.jmedchem.5b01369 BindingDB Entry DOI: 10.7270/Q2TH8PJQ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Protein S100-B (Rattus norvegicus) | BDBM50100895 (2-(4-(4-carbamimidoylphenoxy)phenyl)-1H-indole-6-c...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid PDB UniChem Patents Similars | PDB Article PubMed | n/a | n/a | n/a | 6.00E+3 | n/a | n/a | n/a | n/a | n/a |
University of Maryland Curated by ChEMBL | Assay Description Displacement of TAMRA-TRTK12 from recombinant rat calcium loaded S100-B by Nikolovska-Cleska analysis | J Med Chem 59: 592-608 (2016) Article DOI: 10.1021/acs.jmedchem.5b01369 BindingDB Entry DOI: 10.7270/Q2TH8PJQ | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (crystal) | ||||||||||||
Protein S100-B (Rattus norvegicus) | BDBM50146595 (CHEMBL3765382) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | 4.60E+3 | n/a | n/a | n/a | n/a | n/a |
University of Maryland Curated by ChEMBL | Assay Description Displacement of TAMRA-TRTK12 from recombinant rat calcium loaded S100-B by Nikolovska-Cleska analysis | J Med Chem 59: 592-608 (2016) Article DOI: 10.1021/acs.jmedchem.5b01369 BindingDB Entry DOI: 10.7270/Q2TH8PJQ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Protein S100-B (Rattus norvegicus) | BDBM50146594 (CHEMBL3765771) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | 2.03E+5 | n/a | n/a | n/a | n/a | n/a |
University of Maryland Curated by ChEMBL | Assay Description Displacement of TAMRA-TRTK12 from recombinant rat calcium loaded S100-B by Nikolovska-Cleska analysis | J Med Chem 59: 592-608 (2016) Article DOI: 10.1021/acs.jmedchem.5b01369 BindingDB Entry DOI: 10.7270/Q2TH8PJQ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Protein S100-B (Rattus norvegicus) | BDBM45440 (4-[5-(4-amidinophenoxy)pentoxy]benzamidine;2-hydro...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL DrugBank MCE KEGG PC cid PC sid PDB UniChem Similars | PDB Article PubMed | n/a | n/a | n/a | 4.40E+4 | n/a | n/a | n/a | n/a | n/a |
University of Maryland Curated by ChEMBL | Assay Description Binding affinity to recombinant rat calcium loaded S100-B by fluorescence spectrophotometric analysis | J Med Chem 59: 592-608 (2016) Article DOI: 10.1021/acs.jmedchem.5b01369 BindingDB Entry DOI: 10.7270/Q2TH8PJQ | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (crystal) | ||||||||||||
Protein S100-B (Rattus norvegicus) | BDBM45440 (4-[5-(4-amidinophenoxy)pentoxy]benzamidine;2-hydro...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL DrugBank MCE KEGG PC cid PC sid PDB UniChem Similars | PDB Article PubMed | n/a | n/a | n/a | 5.00E+4 | n/a | n/a | n/a | n/a | n/a |
University of Maryland Curated by ChEMBL | Assay Description Binding affinity to recombinant rat calcium loaded S100-B by isothermal titration calorimetry | J Med Chem 59: 592-608 (2016) Article DOI: 10.1021/acs.jmedchem.5b01369 BindingDB Entry DOI: 10.7270/Q2TH8PJQ | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (crystal) | ||||||||||||
Protein S100-B (Rattus norvegicus) | BDBM50146593 (CHEMBL3764851) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | 500 | n/a | n/a | n/a | n/a | n/a |
University of Maryland Curated by ChEMBL | Assay Description Displacement of TAMRA-TRTK12 from recombinant rat calcium loaded S100-B by Nikolovska-Cleska analysis | J Med Chem 59: 592-608 (2016) Article DOI: 10.1021/acs.jmedchem.5b01369 BindingDB Entry DOI: 10.7270/Q2TH8PJQ | |||||||||||
More data for this Ligand-Target Pair |