Compile Data Set for Download or QSAR

Found 304 hits with Last Name = 'antane' and Initial = 's'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
5-hydroxytryptamine receptor 6 (Homo sapiens (Human))	BDBM50300820 (CHEMBL565723 | N-(2-{3-[(3-Chlorophenyl)sulfonyl]-...) Show SMILES CNCCn1cc(c2cccnc12)S(=O)(=O)c1cccc(Cl)c1 Show InChI InChI=1S/C16H16ClN3O2S/c1-18-8-9-20-11-15(14-6-3-7-19-16(14)20)23(21,22)13-5-2-4-12(17)10-13/h2-7,10-11,18H,8-9H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	0.300	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Displacement of [3H]LSD from human cloned 5HT6 receptor expressed in HeLa cells				Bioorg Med Chem 17: 5153-63 (2009) Article DOI: 10.1016/j.bmc.2009.05.055 BindingDB Entry DOI: 10.7270/Q25T3KJS
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 6 (Homo sapiens (Human))	BDBM50300845 (CHEMBL565746 | N-(2-{3-[(6-Chloroimidazo[2,1-b][1,...) Show SMILES CNCCn1cc(c2cccnc12)S(=O)(=O)c1c(Cl)nc2sccn12 Show InChI InChI=1S/C15H14ClN5O2S2/c1-17-5-6-20-9-11(10-3-2-4-18-13(10)20)25(22,23)14-12(16)19-15-21(14)7-8-24-15/h2-4,7-9,17H,5-6H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	0.900	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Displacement of [3H]LSD from human cloned 5HT6 receptor expressed in HeLa cells				Bioorg Med Chem 17: 5153-63 (2009) Article DOI: 10.1016/j.bmc.2009.05.055 BindingDB Entry DOI: 10.7270/Q25T3KJS
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 6 (Homo sapiens (Human))	BDBM50300842 (CHEMBL565724 | N-(2-{3-[(6-Chloroimidazo[2,1-b][1,...) Show SMILES CN(C)CCn1cc(c2cccnc12)S(=O)(=O)c1c(Cl)nc2sccn12 Show InChI InChI=1S/C16H16ClN5O2S2/c1-20(2)6-7-21-10-12(11-4-3-5-18-14(11)21)26(23,24)15-13(17)19-16-22(15)8-9-25-16/h3-5,8-10H,6-7H2,1-2H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	0.900	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Displacement of [3H]LSD from human cloned 5HT6 receptor expressed in HeLa cells				Bioorg Med Chem 17: 5153-63 (2009) Article DOI: 10.1016/j.bmc.2009.05.055 BindingDB Entry DOI: 10.7270/Q25T3KJS
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 6 (Homo sapiens (Human))	BDBM50300843 (CHEMBL565976 | N-(2-{3-[(3-Fluorophenyl)sulfonyl]-...) Show SMILES CNCCn1cc(c2cccnc12)S(=O)(=O)c1cccc(F)c1 Show InChI InChI=1S/C16H16FN3O2S/c1-18-8-9-20-11-15(14-6-3-7-19-16(14)20)23(21,22)13-5-2-4-12(17)10-13/h2-7,10-11,18H,8-9H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Displacement of [3H]LSD from human cloned 5HT6 receptor expressed in HeLa cells				Bioorg Med Chem 17: 5153-63 (2009) Article DOI: 10.1016/j.bmc.2009.05.055 BindingDB Entry DOI: 10.7270/Q25T3KJS
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 6 (Homo sapiens (Human))	BDBM50300838 (CHEMBL565552 | N,N-Dimethyl-N-{2-[3-(1-naphthylsul...) Show SMILES CN(C)CCn1cc(c2cccnc12)S(=O)(=O)c1cccc2ccccc12 Show InChI InChI=1S/C21H21N3O2S/c1-23(2)13-14-24-15-20(18-10-6-12-22-21(18)24)27(25,26)19-11-5-8-16-7-3-4-9-17(16)19/h3-12,15H,13-14H2,1-2H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Displacement of [3H]LSD from human cloned 5HT6 receptor expressed in HeLa cells				Bioorg Med Chem 17: 5153-63 (2009) Article DOI: 10.1016/j.bmc.2009.05.055 BindingDB Entry DOI: 10.7270/Q25T3KJS
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 6 (Homo sapiens (Human))	BDBM50313121 (3-(3-chlorophenylsulfonyl)-1-(1-methylpyrrolidin-3...) Show SMILES CN1CCC(C1)n1cc(c2ccccc12)S(=O)(=O)c1cccc(Cl)c1 Show InChI InChI=1S/C19H19ClN2O2S/c1-21-10-9-15(12-21)22-13-19(17-7-2-3-8-18(17)22)25(23,24)16-6-4-5-14(20)11-16/h2-8,11,13,15H,9-10,12H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.30	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Pharmaceuticals Curated by ChEMBL					Assay Description Displacement of [3H]LSD from human 5-HT6 receptor expressed in human HeLa cells after 2 hrs				Bioorg Med Chem Lett 20: 1657-60 (2010) Article DOI: 10.1016/j.bmcl.2010.01.073 BindingDB Entry DOI: 10.7270/Q2ZC830C
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 6 (Homo sapiens (Human))	BDBM50313125 (8-(1-(pyrrolidin-3-yl)-1H-indol-3-ylsulfonyl)quino...) Show SMILES O=S(=O)(c1cn(C2CCNC2)c2ccccc12)c1cccc2cccnc12 Show InChI InChI=1S/C21H19N3O2S/c25-27(26,19-9-3-5-15-6-4-11-23-21(15)19)20-14-24(16-10-12-22-13-16)18-8-2-1-7-17(18)20/h1-9,11,14,16,22H,10,12-13H2	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Pharmaceuticals Curated by ChEMBL					Assay Description Displacement of [3H]LSD from human 5-HT6 receptor expressed in human HeLa cells after 2 hrs				Bioorg Med Chem Lett 20: 1657-60 (2010) Article DOI: 10.1016/j.bmcl.2010.01.073 BindingDB Entry DOI: 10.7270/Q2ZC830C
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 6 (Homo sapiens (Human))	BDBM50300839 (2-[3-(1-Naphthylsulfonyl)-1H-pyrrolo[2,3-b]pyridin...) Show SMILES NCCn1cc(c2cccnc12)S(=O)(=O)c1cccc2ccccc12 Show InChI InChI=1S/C19H17N3O2S/c20-10-12-22-13-18(16-8-4-11-21-19(16)22)25(23,24)17-9-3-6-14-5-1-2-7-15(14)17/h1-9,11,13H,10,12,20H2	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.60	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Displacement of [3H]LSD from human cloned 5HT6 receptor expressed in HeLa cells				Bioorg Med Chem 17: 5153-63 (2009) Article DOI: 10.1016/j.bmc.2009.05.055 BindingDB Entry DOI: 10.7270/Q25T3KJS
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 6 (Homo sapiens (Human))	BDBM50303164 (1-(1-(2-(dimethylamino)ethyl)-3-(naphthalen-1-ylsu...) Show SMILES CN(C)CCn1cc(c2nc(ccc12)C(C)=O)S(=O)(=O)c1cccc2ccccc12 Show InChI InChI=1S/C23H23N3O3S/c1-16(27)19-11-12-20-23(24-19)22(15-26(20)14-13-25(2)3)30(28,29)21-10-6-8-17-7-4-5-9-18(17)21/h4-12,15H,13-14H2,1-3H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.70	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Displacement of [3H]LSD from human HT6 receptor expressed in human HeLa cells				Bioorg Med Chem Lett 19: 6935-8 (2009) Article DOI: 10.1016/j.bmcl.2009.10.067 BindingDB Entry DOI: 10.7270/Q20K28PH
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 6 (Homo sapiens (Human))	BDBM50300824 (2-{3-[(3-Chlorophenyl)sulfonyl]-1H-pyrrolo[2,3-b]p...) Show SMILES NCCn1cc(c2cccnc12)S(=O)(=O)c1cccc(Cl)c1 Show InChI InChI=1S/C15H14ClN3O2S/c16-11-3-1-4-12(9-11)22(20,21)14-10-19(8-6-17)15-13(14)5-2-7-18-15/h1-5,7,9-10H,6,8,17H2	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	2	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Displacement of [3H]LSD from human cloned 5HT6 receptor expressed in HeLa cells				Bioorg Med Chem 17: 5153-63 (2009) Article DOI: 10.1016/j.bmc.2009.05.055 BindingDB Entry DOI: 10.7270/Q25T3KJS
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 6 (Homo sapiens (Human))	BDBM50300834 (2-(3-{[3-(Trifluoromethyl)phenyl]sulfonyl}-1Hpyrro...) Show SMILES NCCn1cc(c2cccnc12)S(=O)(=O)c1cccc(c1)C(F)(F)F Show InChI InChI=1S/C16H14F3N3O2S/c17-16(18,19)11-3-1-4-12(9-11)25(23,24)14-10-22(8-6-20)15-13(14)5-2-7-21-15/h1-5,7,9-10H,6,8,20H2	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	2.10	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Displacement of [3H]LSD from human cloned 5HT6 receptor expressed in HeLa cells				Bioorg Med Chem 17: 5153-63 (2009) Article DOI: 10.1016/j.bmc.2009.05.055 BindingDB Entry DOI: 10.7270/Q25T3KJS
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 6 (Homo sapiens (Human))	BDBM50300833 (2-(3-{[2-(Trifluoromethyl)phenyl]sulfonyl}-1Hpyrro...) Show SMILES NCCn1cc(c2cccnc12)S(=O)(=O)c1ccccc1C(F)(F)F Show InChI InChI=1S/C16H14F3N3O2S/c17-16(18,19)12-5-1-2-6-13(12)25(23,24)14-10-22(9-7-20)15-11(14)4-3-8-21-15/h1-6,8,10H,7,9,20H2	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	2.10	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Displacement of [3H]LSD from human cloned 5HT6 receptor expressed in HeLa cells				Bioorg Med Chem 17: 5153-63 (2009) Article DOI: 10.1016/j.bmc.2009.05.055 BindingDB Entry DOI: 10.7270/Q25T3KJS
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 6 (Homo sapiens (Human))	BDBM50300825 (CHEMBL584046 | N,N-Dimethyl-N-(2-{3-[(3-chlorophen...) Show SMILES CN(C)CCn1cc(c2cccnc12)S(=O)(=O)c1cccc(Cl)c1 Show InChI InChI=1S/C17H18ClN3O2S/c1-20(2)9-10-21-12-16(15-7-4-8-19-17(15)21)24(22,23)14-6-3-5-13(18)11-14/h3-8,11-12H,9-10H2,1-2H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	2.30	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Displacement of [3H]LSD from human cloned 5HT6 receptor expressed in HeLa cells				Bioorg Med Chem 17: 5153-63 (2009) Article DOI: 10.1016/j.bmc.2009.05.055 BindingDB Entry DOI: 10.7270/Q25T3KJS
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 6 (Homo sapiens (Human))	BDBM50313126 (8-(1-(1-methylpyrrolidin-3-yl)-1H-indol-3-ylsulfon...) Show SMILES CN1CCC(C1)n1cc(c2ccccc12)S(=O)(=O)c1cccc2cccnc12 Show InChI InChI=1S/C22H21N3O2S/c1-24-13-11-17(14-24)25-15-21(18-8-2-3-9-19(18)25)28(26,27)20-10-4-6-16-7-5-12-23-22(16)20/h2-10,12,15,17H,11,13-14H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	2.80	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Pharmaceuticals Curated by ChEMBL					Assay Description Displacement of [3H]LSD from human 5-HT6 receptor expressed in human HeLa cells after 2 hrs				Bioorg Med Chem Lett 20: 1657-60 (2010) Article DOI: 10.1016/j.bmcl.2010.01.073 BindingDB Entry DOI: 10.7270/Q2ZC830C
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 6 (Homo sapiens (Human))	BDBM50300836 (2-{3-[(3,5-Dichlorophenyl)sulfonyl]-1H-pyrrolo[2,3...) Show SMILES NCCn1cc(c2cccnc12)S(=O)(=O)c1cc(Cl)cc(Cl)c1 Show InChI InChI=1S/C15H13Cl2N3O2S/c16-10-6-11(17)8-12(7-10)23(21,22)14-9-20(5-3-18)15-13(14)2-1-4-19-15/h1-2,4,6-9H,3,5,18H2	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	2.90	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Displacement of [3H]LSD from human cloned 5HT6 receptor expressed in HeLa cells				Bioorg Med Chem 17: 5153-63 (2009) Article DOI: 10.1016/j.bmc.2009.05.055 BindingDB Entry DOI: 10.7270/Q25T3KJS
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 6 (Homo sapiens (Human))	BDBM50313147 (3-(3-chlorophenylsulfonyl)-1-(pyrrolidin-3-yl)-1H-...) Show SMILES Clc1cccc(c1)S(=O)(=O)c1cn(C2CCNC2)c2ccccc12 Show InChI InChI=1S/C18H17ClN2O2S/c19-13-4-3-5-15(10-13)24(22,23)18-12-21(14-8-9-20-11-14)17-7-2-1-6-16(17)18/h1-7,10,12,14,20H,8-9,11H2	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	3.20	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Pharmaceuticals Curated by ChEMBL					Assay Description Displacement of [3H]LSD from human 5-HT6 receptor expressed in human HeLa cells after 2 hrs				Bioorg Med Chem Lett 20: 1657-60 (2010) Article DOI: 10.1016/j.bmcl.2010.01.073 BindingDB Entry DOI: 10.7270/Q2ZC830C
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 6 (Homo sapiens (Human))	BDBM50300841 (CHEMBL583389 | N-(2-{3-[(5-Chlorothien-2-yl)sulfon...) Show SMILES CN(C)CCn1cc(c2cccnc12)S(=O)(=O)c1ccc(Cl)s1 Show InChI InChI=1S/C15H16ClN3O2S2/c1-18(2)8-9-19-10-12(11-4-3-7-17-15(11)19)23(20,21)14-6-5-13(16)22-14/h3-7,10H,8-9H2,1-2H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	3.30	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Displacement of [3H]LSD from human cloned 5HT6 receptor expressed in HeLa cells				Bioorg Med Chem 17: 5153-63 (2009) Article DOI: 10.1016/j.bmc.2009.05.055 BindingDB Entry DOI: 10.7270/Q25T3KJS
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 6 (Homo sapiens (Human))	BDBM50313141 (3-(3-fluorophenylsulfonyl)-1-(1-methylpyrrolidin-3...) Show SMILES CN1CCC(C1)n1cc(c2ccccc12)S(=O)(=O)c1cccc(F)c1 Show InChI InChI=1S/C19H19FN2O2S/c1-21-10-9-15(12-21)22-13-19(17-7-2-3-8-18(17)22)25(23,24)16-6-4-5-14(20)11-16/h2-8,11,13,15H,9-10,12H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	3.5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Pharmaceuticals Curated by ChEMBL					Assay Description Displacement of [3H]LSD from human 5-HT6 receptor expressed in human HeLa cells after 2 hrs				Bioorg Med Chem Lett 20: 1657-60 (2010) Article DOI: 10.1016/j.bmcl.2010.01.073 BindingDB Entry DOI: 10.7270/Q2ZC830C
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 6 (Homo sapiens (Human))	BDBM50155130 (CHEMBL185958 | Dimethyl-{2-[3-(naphthalene-1-sulfo...) Show SMILES CN(C)CCn1cc(c2ccccc12)S(=O)(=O)c1cccc2ccccc12 Show InChI InChI=1S/C22H22N2O2S/c1-23(2)14-15-24-16-22(19-11-5-6-12-20(19)24)27(25,26)21-13-7-9-17-8-3-4-10-18(17)21/h3-13,16H,14-15H2,1-2H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	3.70	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Binding affinity against human 5-hydroxytryptamine 6 receptor transfected in HeLa cells				Bioorg Med Chem Lett 14: 5499-502 (2004) Article DOI: 10.1016/j.bmcl.2004.09.003 BindingDB Entry DOI: 10.7270/Q2SB457X
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 6 (Homo sapiens (Human))	BDBM50303163 (1-(3-(4-bromophenylsulfonyl)-1-(2-(dimethylamino)e...) Show SMILES CN(C)CCn1cc(c2nc(ccc12)C(C)=O)S(=O)(=O)c1ccc(Br)cc1 Show InChI InChI=1S/C19H20BrN3O3S/c1-13(24)16-8-9-17-19(21-16)18(12-23(17)11-10-22(2)3)27(25,26)15-6-4-14(20)5-7-15/h4-9,12H,10-11H2,1-3H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	3.90	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Displacement of [3H]LSD from human HT6 receptor expressed in human HeLa cells				Bioorg Med Chem Lett 19: 6935-8 (2009) Article DOI: 10.1016/j.bmcl.2009.10.067 BindingDB Entry DOI: 10.7270/Q20K28PH
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 6 (Homo sapiens (Human))	BDBM50313118 (5-fluoro-3-(3-fluorophenylsulfonyl)-1-(piperidin-3...) Show SMILES Fc1cccc(c1)S(=O)(=O)c1cn(C2CCCNC2)c2ccc(F)cc12 Show InChI InChI=1S/C19H18F2N2O2S/c20-13-3-1-5-16(9-13)26(24,25)19-12-23(15-4-2-8-22-11-15)18-7-6-14(21)10-17(18)19/h1,3,5-7,9-10,12,15,22H,2,4,8,11H2	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Pharmaceuticals Curated by ChEMBL					Assay Description Displacement of [3H]LSD from human 5-HT6 receptor expressed in human HeLa cells after 2 hrs				Bioorg Med Chem Lett 20: 1657-60 (2010) Article DOI: 10.1016/j.bmcl.2010.01.073 BindingDB Entry DOI: 10.7270/Q2ZC830C
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 6 (Homo sapiens (Human))	BDBM50300830 (2-[2-Methyl-3-(phenylsulfonyl)-1H-pyrrolo[2,3-b]py...) Show SMILES Cc1c(c2cccnc2n1CCN)S(=O)(=O)c1ccccc1 Show InChI InChI=1S/C16H17N3O2S/c1-12-15(22(20,21)13-6-3-2-4-7-13)14-8-5-10-18-16(14)19(12)11-9-17/h2-8,10H,9,11,17H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	4.20	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Displacement of [3H]LSD from human cloned 5HT6 receptor expressed in HeLa cells				Bioorg Med Chem 17: 5153-63 (2009) Article DOI: 10.1016/j.bmc.2009.05.055 BindingDB Entry DOI: 10.7270/Q25T3KJS
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 6 (Homo sapiens (Human))	BDBM50300835 (CHEMBL565977 | N-(2-{3-[(3,5-Dichlorophenyl)sulfon...) Show SMILES CN(C)CCn1cc(c2cccnc12)S(=O)(=O)c1cc(Cl)cc(Cl)c1 Show InChI InChI=1S/C17H17Cl2N3O2S/c1-21(2)6-7-22-11-16(15-4-3-5-20-17(15)22)25(23,24)14-9-12(18)8-13(19)10-14/h3-5,8-11H,6-7H2,1-2H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	4.30	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Displacement of [3H]LSD from human cloned 5HT6 receptor expressed in HeLa cells				Bioorg Med Chem 17: 5153-63 (2009) Article DOI: 10.1016/j.bmc.2009.05.055 BindingDB Entry DOI: 10.7270/Q25T3KJS
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 6 (Homo sapiens (Human))	BDBM50313122 (3-(3-chlorophenylsulfonyl)-6-methoxy-1-(pyrrolidin...) Show SMILES COc1ccc2c(cn(C3CCNC3)c2c1)S(=O)(=O)c1cccc(Cl)c1 Show InChI InChI=1S/C19H19ClN2O3S/c1-25-15-5-6-17-18(10-15)22(14-7-8-21-11-14)12-19(17)26(23,24)16-4-2-3-13(20)9-16/h2-6,9-10,12,14,21H,7-8,11H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	4.60	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Pharmaceuticals Curated by ChEMBL					Assay Description Displacement of [3H]LSD from human 5-HT6 receptor expressed in human HeLa cells after 2 hrs				Bioorg Med Chem Lett 20: 1657-60 (2010) Article DOI: 10.1016/j.bmcl.2010.01.073 BindingDB Entry DOI: 10.7270/Q2ZC830C
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 6 (Homo sapiens (Human))	BDBM50300829 (CHEMBL565730 | N,N-Dimethyl-N-{2-[2-methyl-3-(phen...) Show SMILES CN(C)CCn1c(C)c(c2cccnc12)S(=O)(=O)c1ccccc1 Show InChI InChI=1S/C18H21N3O2S/c1-14-17(24(22,23)15-8-5-4-6-9-15)16-10-7-11-19-18(16)21(14)13-12-20(2)3/h4-11H,12-13H2,1-3H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	4.70	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Displacement of [3H]LSD from human cloned 5HT6 receptor expressed in HeLa cells				Bioorg Med Chem 17: 5153-63 (2009) Article DOI: 10.1016/j.bmc.2009.05.055 BindingDB Entry DOI: 10.7270/Q25T3KJS
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 6 (Homo sapiens (Human))	BDBM50313140 (3-(3-fluorophenylsulfonyl)-1-(pyrrolidin-3-yl)-1H-...) Show SMILES Fc1cccc(c1)S(=O)(=O)c1cn(C2CCNC2)c2ccccc12 Show InChI InChI=1S/C18H17FN2O2S/c19-13-4-3-5-15(10-13)24(22,23)18-12-21(14-8-9-20-11-14)17-7-2-1-6-16(17)18/h1-7,10,12,14,20H,8-9,11H2	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	4.70	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Pharmaceuticals Curated by ChEMBL					Assay Description Displacement of [3H]LSD from human 5-HT6 receptor expressed in human HeLa cells after 2 hrs				Bioorg Med Chem Lett 20: 1657-60 (2010) Article DOI: 10.1016/j.bmcl.2010.01.073 BindingDB Entry DOI: 10.7270/Q2ZC830C
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 6 (Homo sapiens (Human))	BDBM50300827 (2-{3-[(3-Fluorophenyl)sulfonyl]-1H-pyrrolo[2,3-b]p...) Show SMILES NCCn1cc(c2cccnc12)S(=O)(=O)c1cccc(F)c1 Show InChI InChI=1S/C15H14FN3O2S/c16-11-3-1-4-12(9-11)22(20,21)14-10-19(8-6-17)15-13(14)5-2-7-18-15/h1-5,7,9-10H,6,8,17H2	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	4.70	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Displacement of [3H]LSD from human cloned 5HT6 receptor expressed in HeLa cells				Bioorg Med Chem 17: 5153-63 (2009) Article DOI: 10.1016/j.bmc.2009.05.055 BindingDB Entry DOI: 10.7270/Q25T3KJS
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 6 (Homo sapiens (Human))	BDBM50300828 (2-(3-(3-fluorophenylsulfonyl)-1H-pyrrolo[2,3-b]pyr...) Show SMILES CN(C)CCn1cc(c2cccnc12)S(=O)(=O)c1cccc(F)c1 Show InChI InChI=1S/C17H18FN3O2S/c1-20(2)9-10-21-12-16(15-7-4-8-19-17(15)21)24(22,23)14-6-3-5-13(18)11-14/h3-8,11-12H,9-10H2,1-2H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	Article PubMed	4.80	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Displacement of [3H]LSD from human cloned 5HT6 receptor expressed in HeLa cells				Bioorg Med Chem 17: 5153-63 (2009) Article DOI: 10.1016/j.bmc.2009.05.055 BindingDB Entry DOI: 10.7270/Q25T3KJS
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 6 (Homo sapiens (Human))	BDBM50300828 (2-(3-(3-fluorophenylsulfonyl)-1H-pyrrolo[2,3-b]pyr...) Show SMILES CN(C)CCn1cc(c2cccnc12)S(=O)(=O)c1cccc(F)c1 Show InChI InChI=1S/C17H18FN3O2S/c1-20(2)9-10-21-12-16(15-7-4-8-19-17(15)21)24(22,23)14-6-3-5-13(18)11-14/h3-8,11-12H,9-10H2,1-2H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	Article PubMed	4.90	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Displacement of [3H]LSD from human HT6 receptor expressed in human HeLa cells				Bioorg Med Chem Lett 19: 6935-8 (2009) Article DOI: 10.1016/j.bmcl.2009.10.067 BindingDB Entry DOI: 10.7270/Q20K28PH
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 6 (Homo sapiens (Human))	BDBM50155142 (CHEMBL187278 | [2-(1-Benzenesulfonyl-1H-indol-3-yl...) Show SMILES CNCCc1cn(c2ccccc12)S(=O)(=O)c1ccccc1 Show InChI InChI=1S/C17H18N2O2S/c1-18-12-11-14-13-19(17-10-6-5-9-16(14)17)22(20,21)15-7-3-2-4-8-15/h2-10,13,18H,11-12H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Binding affinity against human 5-hydroxytryptamine 6 receptor transfected in HeLa cells				Bioorg Med Chem Lett 14: 5499-502 (2004) Article DOI: 10.1016/j.bmcl.2004.09.003 BindingDB Entry DOI: 10.7270/Q2SB457X
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 6 (Homo sapiens (Human))	BDBM50313120 (5-fluoro-3-(3-fluorophenylsulfonyl)-1-(1-methylpyr...) Show SMILES CN1CCC(C1)n1cc(c2cc(F)ccc12)S(=O)(=O)c1cccc(F)c1 Show InChI InChI=1S/C19H18F2N2O2S/c1-22-8-7-15(11-22)23-12-19(17-10-14(21)5-6-18(17)23)26(24,25)16-4-2-3-13(20)9-16/h2-6,9-10,12,15H,7-8,11H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Pharmaceuticals Curated by ChEMBL					Assay Description Displacement of [3H]LSD from human 5-HT6 receptor expressed in human HeLa cells after 2 hrs				Bioorg Med Chem Lett 20: 1657-60 (2010) Article DOI: 10.1016/j.bmcl.2010.01.073 BindingDB Entry DOI: 10.7270/Q2ZC830C
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 6 (Homo sapiens (Human))	BDBM50313139 (3-(phenylsulfonyl)-1-(pyrrolidin-3-yl)-1H-indole |...) Show SMILES O=S(=O)(c1cn(C2CCNC2)c2ccccc12)c1ccccc1 Show InChI InChI=1S/C18H18N2O2S/c21-23(22,15-6-2-1-3-7-15)18-13-20(14-10-11-19-12-14)17-9-5-4-8-16(17)18/h1-9,13-14,19H,10-12H2	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Pharmaceuticals Curated by ChEMBL					Assay Description Displacement of [3H]LSD from human 5-HT6 receptor expressed in human HeLa cells after 2 hrs				Bioorg Med Chem Lett 20: 1657-60 (2010) Article DOI: 10.1016/j.bmcl.2010.01.073 BindingDB Entry DOI: 10.7270/Q2ZC830C
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 6 (Homo sapiens (Human))	BDBM50300831 (2-[3-(Phenylsulfonyl)-1H-pyrrolo[2,3-b]pyridin-1-y...) Show SMILES NCCn1cc(c2cccnc12)S(=O)(=O)c1ccccc1 Show InChI InChI=1S/C15H15N3O2S/c16-8-10-18-11-14(13-7-4-9-17-15(13)18)21(19,20)12-5-2-1-3-6-12/h1-7,9,11H,8,10,16H2	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	5.5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Displacement of [3H]LSD from human cloned 5HT6 receptor expressed in HeLa cells				Bioorg Med Chem 17: 5153-63 (2009) Article DOI: 10.1016/j.bmc.2009.05.055 BindingDB Entry DOI: 10.7270/Q25T3KJS
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 6 (Homo sapiens (Human))	BDBM50313137 (8-(1-(piperidin-3-yl)-1H-indol-3-ylsulfonyl)quinol...) Show SMILES O=S(=O)(c1cn(C2CCCNC2)c2ccccc12)c1cccc2cccnc12 Show InChI InChI=1S/C22H21N3O2S/c26-28(27,20-11-3-6-16-7-4-13-24-22(16)20)21-15-25(17-8-5-12-23-14-17)19-10-2-1-9-18(19)21/h1-4,6-7,9-11,13,15,17,23H,5,8,12,14H2	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	5.60	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Pharmaceuticals Curated by ChEMBL					Assay Description Displacement of [3H]LSD from human 5-HT6 receptor expressed in human HeLa cells after 2 hrs				Bioorg Med Chem Lett 20: 1657-60 (2010) Article DOI: 10.1016/j.bmcl.2010.01.073 BindingDB Entry DOI: 10.7270/Q2ZC830C
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 6 (Homo sapiens (Human))	BDBM50155135 (CHEMBL184652 | Methyl-{2-[3-(naphthalene-1-sulfony...) Show SMILES CNCCn1cc(c2ccccc12)S(=O)(=O)c1cccc2ccccc12 Show InChI InChI=1S/C21H20N2O2S/c1-22-13-14-23-15-21(18-10-4-5-11-19(18)23)26(24,25)20-12-6-8-16-7-2-3-9-17(16)20/h2-12,15,22H,13-14H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	5.70	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Binding affinity against human 5-hydroxytryptamine 6 receptor transfected in HeLa cells				Bioorg Med Chem Lett 14: 5499-502 (2004) Article DOI: 10.1016/j.bmcl.2004.09.003 BindingDB Entry DOI: 10.7270/Q2SB457X
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 6 (Homo sapiens (Human))	BDBM50313132 (3-(3-fluorophenylsulfonyl)-1-(piperidin-3-yl)-1H-i...) Show SMILES Fc1cccc(c1)S(=O)(=O)c1cn(C2CCCNC2)c2ccccc12 Show InChI InChI=1S/C19H19FN2O2S/c20-14-5-3-7-16(11-14)25(23,24)19-13-22(15-6-4-10-21-12-15)18-9-2-1-8-17(18)19/h1-3,5,7-9,11,13,15,21H,4,6,10,12H2	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	6	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Pharmaceuticals Curated by ChEMBL					Assay Description Displacement of [3H]LSD from human 5-HT6 receptor expressed in human HeLa cells after 2 hrs				Bioorg Med Chem Lett 20: 1657-60 (2010) Article DOI: 10.1016/j.bmcl.2010.01.073 BindingDB Entry DOI: 10.7270/Q2ZC830C
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 6 (Homo sapiens (Human))	BDBM50313124 (1-(1-methylpyrrolidin-3-yl)-3-(naphthalen-1-ylsulf...) Show SMILES CN1CCC(C1)n1cc(c2ccccc12)S(=O)(=O)c1cccc2ccccc12 Show InChI InChI=1S/C23H22N2O2S/c1-24-14-13-18(15-24)25-16-23(20-10-4-5-11-21(20)25)28(26,27)22-12-6-8-17-7-2-3-9-19(17)22/h2-12,16,18H,13-15H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	6	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Pharmaceuticals Curated by ChEMBL					Assay Description Displacement of [3H]LSD from human 5-HT6 receptor expressed in human HeLa cells after 2 hrs				Bioorg Med Chem Lett 20: 1657-60 (2010) Article DOI: 10.1016/j.bmcl.2010.01.073 BindingDB Entry DOI: 10.7270/Q2ZC830C
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 6 (Homo sapiens (Human))	BDBM50313119 (1-(1-methylpiperidin-3-yl)-3-(naphthalen-1-ylsulfo...) Show SMILES CN1CCCC(C1)n1cc(c2ccccc12)S(=O)(=O)c1cccc2ccccc12 Show InChI InChI=1S/C24H24N2O2S/c1-25-15-7-10-19(16-25)26-17-24(21-12-4-5-13-22(21)26)29(27,28)23-14-6-9-18-8-2-3-11-20(18)23/h2-6,8-9,11-14,17,19H,7,10,15-16H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	7.10	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Pharmaceuticals Curated by ChEMBL					Assay Description Displacement of [3H]LSD from human 5-HT6 receptor expressed in human HeLa cells after 2 hrs				Bioorg Med Chem Lett 20: 1657-60 (2010) Article DOI: 10.1016/j.bmcl.2010.01.073 BindingDB Entry DOI: 10.7270/Q2ZC830C
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 6 (Homo sapiens (Human))	BDBM50313131 (1-(1-ethylpiperidin-3-yl)-3-(phenylsulfonyl)-1H-in...) Show SMILES CCN1CCCC(C1)n1cc(c2ccccc12)S(=O)(=O)c1ccccc1 Show InChI InChI=1S/C21H24N2O2S/c1-2-22-14-8-9-17(15-22)23-16-21(19-12-6-7-13-20(19)23)26(24,25)18-10-4-3-5-11-18/h3-7,10-13,16-17H,2,8-9,14-15H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	7.30	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Pharmaceuticals Curated by ChEMBL					Assay Description Displacement of [3H]LSD from human 5-HT6 receptor expressed in human HeLa cells after 2 hrs				Bioorg Med Chem Lett 20: 1657-60 (2010) Article DOI: 10.1016/j.bmcl.2010.01.073 BindingDB Entry DOI: 10.7270/Q2ZC830C
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 6 (Homo sapiens (Human))	BDBM50300837 (CHEMBL568249 | N-(2-{3-[(2,6-Dichlorophenyl)sulfon...) Show SMILES CN(C)CCn1cc(c2cccnc12)S(=O)(=O)c1c(Cl)cccc1Cl Show InChI InChI=1S/C17H17Cl2N3O2S/c1-21(2)9-10-22-11-15(12-5-4-8-20-17(12)22)25(23,24)16-13(18)6-3-7-14(16)19/h3-8,11H,9-10H2,1-2H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	9	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Displacement of [3H]LSD from human cloned 5HT6 receptor expressed in HeLa cells				Bioorg Med Chem 17: 5153-63 (2009) Article DOI: 10.1016/j.bmc.2009.05.055 BindingDB Entry DOI: 10.7270/Q25T3KJS
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 6 (Homo sapiens (Human))	BDBM50313143 (5-fluoro-3-(3-fluorophenylsulfonyl)-1-(pyrrolidin-...) Show SMILES Fc1cccc(c1)S(=O)(=O)c1cn(C2CCNC2)c2ccc(F)cc12 Show InChI InChI=1S/C18H16F2N2O2S/c19-12-2-1-3-15(8-12)25(23,24)18-11-22(14-6-7-21-10-14)17-5-4-13(20)9-16(17)18/h1-5,8-9,11,14,21H,6-7,10H2	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	9.60	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Pharmaceuticals Curated by ChEMBL					Assay Description Displacement of [3H]LSD from human 5-HT6 receptor expressed in human HeLa cells after 2 hrs				Bioorg Med Chem Lett 20: 1657-60 (2010) Article DOI: 10.1016/j.bmcl.2010.01.073 BindingDB Entry DOI: 10.7270/Q2ZC830C
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 6 (Homo sapiens (Human))	BDBM21341 (2-[1-(benzenesulfonyl)-1H-indol-3-yl]ethan-1-amine...) Show SMILES NCCc1cn(c2ccccc12)S(=O)(=O)c1ccccc1 Show InChI InChI=1S/C16H16N2O2S/c17-11-10-13-12-18(16-9-5-4-8-15(13)16)21(19,20)14-6-2-1-3-7-14/h1-9,12H,10-11,17H2	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	10.3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Binding affinity against human 5-hydroxytryptamine 6 receptor transfected in HeLa cells				Bioorg Med Chem Lett 14: 5499-502 (2004) Article DOI: 10.1016/j.bmcl.2004.09.003 BindingDB Entry DOI: 10.7270/Q2SB457X
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 6 (Homo sapiens (Human))	BDBM50313133 (3-(3-fluorophenylsulfonyl)-5-methoxy-1-(piperidin-...) Show SMILES COc1ccc2n(cc(c2c1)S(=O)(=O)c1cccc(F)c1)C1CCCNC1 Show InChI InChI=1S/C20H21FN2O3S/c1-26-16-7-8-19-18(11-16)20(13-23(19)15-5-3-9-22-12-15)27(24,25)17-6-2-4-14(21)10-17/h2,4,6-8,10-11,13,15,22H,3,5,9,12H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	10.7	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Pharmaceuticals Curated by ChEMBL					Assay Description Displacement of [3H]LSD from human 5-HT6 receptor expressed in human HeLa cells after 2 hrs				Bioorg Med Chem Lett 20: 1657-60 (2010) Article DOI: 10.1016/j.bmcl.2010.01.073 BindingDB Entry DOI: 10.7270/Q2ZC830C
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 6 (Homo sapiens (Human))	BDBM50303162 (1-(1-(2-(dimethylamino)ethyl)-3-(3-fluorophenylsul...) Show SMILES CN(C)CCn1cc(c2nc(ccc12)C(C)=O)S(=O)(=O)c1cccc(F)c1 Show InChI InChI=1S/C19H20FN3O3S/c1-13(24)16-7-8-17-19(21-16)18(12-23(17)10-9-22(2)3)27(25,26)15-6-4-5-14(20)11-15/h4-8,11-12H,9-10H2,1-3H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	11.3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Displacement of [3H]LSD from human HT6 receptor expressed in human HeLa cells				Bioorg Med Chem Lett 19: 6935-8 (2009) Article DOI: 10.1016/j.bmcl.2009.10.067 BindingDB Entry DOI: 10.7270/Q20K28PH
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 6 (Homo sapiens (Human))	BDBM50300844 (CHEMBL568673 | N-(2-{3-[(2,5-Dichlorophenyl)sulfon...) Show SMILES CN(C)CCn1cc(c2cccnc12)S(=O)(=O)c1cc(Cl)ccc1Cl Show InChI InChI=1S/C17H17Cl2N3O2S/c1-21(2)8-9-22-11-16(13-4-3-7-20-17(13)22)25(23,24)15-10-12(18)5-6-14(15)19/h3-7,10-11H,8-9H2,1-2H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	11.7	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Displacement of [3H]LSD from human cloned 5HT6 receptor expressed in HeLa cells				Bioorg Med Chem 17: 5153-63 (2009) Article DOI: 10.1016/j.bmc.2009.05.055 BindingDB Entry DOI: 10.7270/Q25T3KJS
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 6 (Homo sapiens (Human))	BDBM21366 ((2-{3-[(3-fluorobenzene)sulfonyl]-1H-indol-1-yl}et...) Show SMILES CN(C)CCn1cc(c2ccccc12)S(=O)(=O)c1cccc(F)c1 Show InChI InChI=1S/C18H19FN2O2S/c1-20(2)10-11-21-13-18(16-8-3-4-9-17(16)21)24(22,23)15-7-5-6-14(19)12-15/h3-9,12-13H,10-11H2,1-2H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	13	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Binding affinity against human 5-hydroxytryptamine 6 receptor transfected in HeLa cells				Bioorg Med Chem Lett 14: 5499-502 (2004) Article DOI: 10.1016/j.bmcl.2004.09.003 BindingDB Entry DOI: 10.7270/Q2SB457X
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 6 (Homo sapiens (Human))	BDBM50313130 (3-(phenylsulfonyl)-1-(piperidin-3-yl)-1H-indole | ...) Show SMILES O=S(=O)(c1cn(C2CCCNC2)c2ccccc12)c1ccccc1 Show InChI InChI=1S/C19H20N2O2S/c22-24(23,16-8-2-1-3-9-16)19-14-21(15-7-6-12-20-13-15)18-11-5-4-10-17(18)19/h1-5,8-11,14-15,20H,6-7,12-13H2	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	13	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Pharmaceuticals Curated by ChEMBL					Assay Description Displacement of [3H]LSD from human 5-HT6 receptor expressed in human HeLa cells after 2 hrs				Bioorg Med Chem Lett 20: 1657-60 (2010) Article DOI: 10.1016/j.bmcl.2010.01.073 BindingDB Entry DOI: 10.7270/Q2ZC830C
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 6 (Homo sapiens (Human))	BDBM50313145 (5-chloro-3-(3-fluorophenylsulfonyl)-1-(pyrrolidin-...) Show SMILES Fc1cccc(c1)S(=O)(=O)c1cn(C2CCNC2)c2ccc(Cl)cc12 Show InChI InChI=1S/C18H16ClFN2O2S/c19-12-4-5-17-16(8-12)18(11-22(17)14-6-7-21-10-14)25(23,24)15-3-1-2-13(20)9-15/h1-5,8-9,11,14,21H,6-7,10H2	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	15	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Pharmaceuticals Curated by ChEMBL					Assay Description Displacement of [3H]LSD from human 5-HT6 receptor expressed in human HeLa cells after 2 hrs				Bioorg Med Chem Lett 20: 1657-60 (2010) Article DOI: 10.1016/j.bmcl.2010.01.073 BindingDB Entry DOI: 10.7270/Q2ZC830C
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 6 (Homo sapiens (Human))	BDBM50300840 (CHEMBL565753 | N,N-Dimethyl-N-{2-[3-(thien-2-ylsul...) Show SMILES CN(C)CCn1cc(c2cccnc12)S(=O)(=O)c1cccs1 Show InChI InChI=1S/C15H17N3O2S2/c1-17(2)8-9-18-11-13(12-5-3-7-16-15(12)18)22(19,20)14-6-4-10-21-14/h3-7,10-11H,8-9H2,1-2H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	15	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Displacement of [3H]LSD from human cloned 5HT6 receptor expressed in HeLa cells				Bioorg Med Chem 17: 5153-63 (2009) Article DOI: 10.1016/j.bmc.2009.05.055 BindingDB Entry DOI: 10.7270/Q25T3KJS
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 6 (Homo sapiens (Human))	BDBM50155138 (CHEMBL360181 | [2-(3-Benzenesulfonyl-indol-1-yl)-e...) Show SMILES CNCCn1cc(c2ccccc12)S(=O)(=O)c1ccccc1 Show InChI InChI=1S/C17H18N2O2S/c1-18-11-12-19-13-17(15-9-5-6-10-16(15)19)22(20,21)14-7-3-2-4-8-14/h2-10,13,18H,11-12H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	15.5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Binding affinity against human 5-hydroxytryptamine 6 receptor transfected in HeLa cells				Bioorg Med Chem Lett 14: 5499-502 (2004) Article DOI: 10.1016/j.bmcl.2004.09.003 BindingDB Entry DOI: 10.7270/Q2SB457X
					More data for this Ligand-Target Pair

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