Compile Data Set for Download or QSAR

Found 442 hits with Last Name = 'arndt' and Initial = 'k'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Melanin-concentrating hormone receptor 1 (RAT)	BDBM50107746 (CHEMBL3600828) Show SMILES Clc1ccc(cc1)-c1ccc(nc1)C#Cc1ccc(OCCN2CCCC2)cc1 Show InChI InChI=1S/C25H23ClN2O/c26-23-9-6-21(7-10-23)22-8-12-24(27-19-22)11-3-20-4-13-25(14-5-20)29-18-17-28-15-1-2-16-28/h4-10,12-14,19H,1-2,15-18H2	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Boehringer Ingelheim Pharma GmbH& Co. KG Curated by ChEMBL					Assay Description Antagonist activity against rat MCHR1				Bioorg Med Chem Lett 25: 3264-9 (2015) Article DOI: 10.1016/j.bmcl.2015.05.077 BindingDB Entry DOI: 10.7270/Q25D8TMB
					More data for this Ligand-Target Pair
Melanin-concentrating hormone receptor 1 (Homo sapiens (Human))	BDBM142122 (US8933079, 149 | US8933079, 150 | US8933079, 9.1) Show SMILES COc1ccc(COc2cnn(CC(=O)c3ccc(CN(C)C)cc3C)c(=O)c2)nc1 Show InChI InChI=1S/C23H26N4O4/c1-16-9-17(13-26(2)3)5-8-21(16)22(28)14-27-23(29)10-20(12-25-27)31-15-18-6-7-19(30-4)11-24-18/h5-12H,13-15H2,1-4H3	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	14	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Boehringer Ingelheim Pharma GmbH& Co. KG Curated by ChEMBL					Assay Description Binding affinity to human MCH-R1 expressed in CHO/Galpha16 cells				Bioorg Med Chem Lett 25: 3275-80 (2015) Article DOI: 10.1016/j.bmcl.2015.05.065 BindingDB Entry DOI: 10.7270/Q2T43VV4
					More data for this Ligand-Target Pair
Proto-oncogene tyrosine-protein kinase Src (Homo sapiens (Human))	BDBM4560 (4-Phenylamino-3-quinolinecarbonitrile deriv. 31i |...) Show SMILES COc1cc(Nc2c(cnc3cc(OCCCN4CCC(O)CC4)c(OC)cc23)C#N)c(Cl)cc1Cl Show InChI InChI=1S/C26H28Cl2N4O4/c1-34-23-13-22(19(27)11-20(23)28)31-26-16(14-29)15-30-21-12-25(24(35-2)10-18(21)26)36-9-3-6-32-7-4-17(33)5-8-32/h10-13,15,17,33H,3-9H2,1-2H3,(H,30,31)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	0.640	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth-Ayerst Research					Assay Description Src kinase activity was measured in an ELISA format. IC50 is the inhibitor concentration which inhibits 50% of kinase activity that catalyzes the tra...				J Med Chem 44: 3965-77 (2001) Article DOI: 10.1021/jm0102250 BindingDB Entry DOI: 10.7270/Q2TD9VHP
					More data for this Ligand-Target Pair
Proto-oncogene tyrosine-protein kinase Src (Homo sapiens (Human))	BDBM4557 (4-Phenylamino-3-quinolinecarbonitrile deriv. 31f |...) Show SMILES COc1cc(Nc2c(cnc3cc(OCCCN4CCN(CCO)CC4)c(OC)cc23)C#N)c(Cl)cc1Cl Show InChI InChI=1S/C27H31Cl2N5O4/c1-36-24-15-23(20(28)13-21(24)29)32-27-18(16-30)17-31-22-14-26(25(37-2)12-19(22)27)38-11-3-4-33-5-7-34(8-6-33)9-10-35/h12-15,17,35H,3-11H2,1-2H3,(H,31,32)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	0.760	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth-Ayerst Research					Assay Description Src kinase activity was measured in an ELISA format. IC50 is the inhibitor concentration which inhibits 50% of kinase activity that catalyzes the tra...				J Med Chem 44: 3965-77 (2001) Article DOI: 10.1021/jm0102250 BindingDB Entry DOI: 10.7270/Q2TD9VHP
					More data for this Ligand-Target Pair
Proto-oncogene tyrosine-protein kinase Src (Homo sapiens (Human))	BDBM4553 (4-Phenylamino-3-quinolinecarbonitrile deriv. 31b |...) Show SMILES CCN1CCN(CCCOc2cc3ncc(C#N)c(Nc4cc(OC)c(Cl)cc4Cl)c3cc2OC)CC1 Show InChI InChI=1S/C27H31Cl2N5O3/c1-4-33-7-9-34(10-8-33)6-5-11-37-26-14-22-19(12-25(26)36-3)27(18(16-30)17-31-22)32-23-15-24(35-2)21(29)13-20(23)28/h12-15,17H,4-11H2,1-3H3,(H,31,32)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	0.770	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth-Ayerst Research					Assay Description Src kinase activity was measured in an ELISA format. IC50 is the inhibitor concentration which inhibits 50% of kinase activity that catalyzes the tra...				J Med Chem 44: 3965-77 (2001) Article DOI: 10.1021/jm0102250 BindingDB Entry DOI: 10.7270/Q2TD9VHP
					More data for this Ligand-Target Pair
Proto-oncogene tyrosine-protein kinase Src (Homo sapiens (Human))	BDBM4543 (4-Phenylamino-3-quinolinecarbonitrile deriv. 2c | ...) Show SMILES COc1cc(Nc2c(cnc3cc(OCCCN4CCOCC4)c(OC)cc23)C#N)c(Cl)cc1Cl Show InChI InChI=1S/C25H26Cl2N4O4/c1-32-22-13-21(18(26)11-19(22)27)30-25-16(14-28)15-29-20-12-24(23(33-2)10-17(20)25)35-7-3-4-31-5-8-34-9-6-31/h10-13,15H,3-9H2,1-2H3,(H,29,30)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	0.800	n/a	n/a	n/a	n/a	7.5	30
Wyeth-Ayerst Research					Assay Description Src kinase activity was measured in an ELISA format. IC50 is the inhibitor concentration which inhibits 50% of kinase activity that catalyzes the tra...				J Med Chem 44: 3965-77 (2001) Article DOI: 10.1021/jm0102250 BindingDB Entry DOI: 10.7270/Q2TD9VHP
					More data for this Ligand-Target Pair
Proto-oncogene tyrosine-protein kinase Src (Homo sapiens (Human))	BDBM4544 (4-Phenylamino-3-quinolinecarbonitrile deriv. 2d | ...) Show SMILES COc1cc(Nc2c(cnc3cc(OCCCN4CCOCC4)c(OC)cc23)C#N)c(Br)cc1Cl Show InChI InChI=1S/C25H26BrClN4O4/c1-32-22-13-21(18(26)11-19(22)27)30-25-16(14-28)15-29-20-12-24(23(33-2)10-17(20)25)35-7-3-4-31-5-8-34-9-6-31/h10-13,15H,3-9H2,1-2H3,(H,29,30)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	0.950	n/a	n/a	n/a	n/a	7.5	30
Wyeth-Ayerst Research					Assay Description Src kinase activity was measured in an ELISA format. IC50 is the inhibitor concentration which inhibits 50% of kinase activity that catalyzes the tra...				J Med Chem 44: 3965-77 (2001) Article DOI: 10.1021/jm0102250 BindingDB Entry DOI: 10.7270/Q2TD9VHP
					More data for this Ligand-Target Pair
Melanin-concentrating hormone receptor 1 (Homo sapiens (Human))	BDBM50107818 (CHEMBL3600811) Show SMILES Fc1cc(ccc1-c1ccc(Cl)cc1)C(=O)NCCc1ccc(CN2CCCC2)cc1 Show InChI InChI=1S/C26H26ClFN2O/c27-23-10-7-21(8-11-23)24-12-9-22(17-25(24)28)26(31)29-14-13-19-3-5-20(6-4-19)18-30-15-1-2-16-30/h3-12,17H,1-2,13-16,18H2,(H,29,31)	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1	n/a	n/a	n/a	n/a	n/a	n/a
Boehringer Ingelheim Pharma GmbH& Co. KG Curated by ChEMBL					Assay Description Displacement of [125I]-MCH from human MCHR1 expressed in CHO/Galpha16 cell membranes by scintillation counting method				Bioorg Med Chem Lett 25: 3264-9 (2015) Article DOI: 10.1016/j.bmcl.2015.05.077 BindingDB Entry DOI: 10.7270/Q25D8TMB
					More data for this Ligand-Target Pair
Melanin-concentrating hormone receptor 1 (Homo sapiens (Human))	BDBM50107817 (CHEMBL3600810) Show SMILES Fc1cc(ccc1C(=O)NCCc1ccc(CN2CCCC2)cc1)-c1ccc(Cl)cc1 Show InChI InChI=1S/C26H26ClFN2O/c27-23-10-7-21(8-11-23)22-9-12-24(25(28)17-22)26(31)29-14-13-19-3-5-20(6-4-19)18-30-15-1-2-16-30/h3-12,17H,1-2,13-16,18H2,(H,29,31)	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1	n/a	n/a	n/a	n/a	n/a	n/a
Boehringer Ingelheim Pharma GmbH& Co. KG Curated by ChEMBL					Assay Description Displacement of [125I]-MCH from human MCHR1 expressed in CHO/Galpha16 cell membranes by scintillation counting method				Bioorg Med Chem Lett 25: 3264-9 (2015) Article DOI: 10.1016/j.bmcl.2015.05.077 BindingDB Entry DOI: 10.7270/Q25D8TMB
					More data for this Ligand-Target Pair
Proto-oncogene tyrosine-protein kinase Src (Homo sapiens (Human))	BDBM4556 (4-Phenylamino-3-quinolinecarbonitrile deriv. 31e |...) Show SMILES COc1cc(Nc2c(cnc3cc(OCCCN4CCNCC4)c(OC)cc23)C#N)c(Cl)cc1Cl Show InChI InChI=1S/C25H27Cl2N5O3/c1-33-22-13-21(18(26)11-19(22)27)31-25-16(14-28)15-30-20-12-24(23(34-2)10-17(20)25)35-9-3-6-32-7-4-29-5-8-32/h10-13,15,29H,3-9H2,1-2H3,(H,30,31)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	1.10	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth-Ayerst Research					Assay Description Src kinase activity was measured in an ELISA format. IC50 is the inhibitor concentration which inhibits 50% of kinase activity that catalyzes the tra...				J Med Chem 44: 3965-77 (2001) Article DOI: 10.1021/jm0102250 BindingDB Entry DOI: 10.7270/Q2TD9VHP
					More data for this Ligand-Target Pair
Proto-oncogene tyrosine-protein kinase Src (Homo sapiens (Human))	BDBM4555 (4-Phenylamino-3-quinolinecarbonitrile deriv. 31d |...) Show SMILES CCCN1CCN(CCCOc2cc3ncc(C#N)c(Nc4cc(OC)c(Cl)cc4Cl)c3cc2OC)CC1 Show InChI InChI=1S/C28H33Cl2N5O3/c1-4-6-34-8-10-35(11-9-34)7-5-12-38-27-15-23-20(13-26(27)37-3)28(19(17-31)18-32-23)33-24-16-25(36-2)22(30)14-21(24)29/h13-16,18H,4-12H2,1-3H3,(H,32,33)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	1.10	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth-Ayerst Research					Assay Description Src kinase activity was measured in an ELISA format. IC50 is the inhibitor concentration which inhibits 50% of kinase activity that catalyzes the tra...				J Med Chem 44: 3965-77 (2001) Article DOI: 10.1021/jm0102250 BindingDB Entry DOI: 10.7270/Q2TD9VHP
					More data for this Ligand-Target Pair
Proto-oncogene tyrosine-protein kinase Src (Homo sapiens (Human))	BDBM4547 (4-Phenylamino-3-quinolinecarbonitrile deriv. 2g | ...) Show SMILES COc1cc(Nc2c(cnc3cc(OCCCN4CCOCC4)c(OC)cc23)C#N)c(Cl)cc1C Show InChI InChI=1S/C26H29ClN4O4/c1-17-11-20(27)22(14-23(17)32-2)30-26-18(15-28)16-29-21-13-25(24(33-3)12-19(21)26)35-8-4-5-31-6-9-34-10-7-31/h11-14,16H,4-10H2,1-3H3,(H,29,30)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	1.10	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth-Ayerst Research					Assay Description Src kinase activity was measured in an ELISA format. IC50 is the inhibitor concentration which inhibits 50% of kinase activity that catalyzes the tra...				J Med Chem 44: 3965-77 (2001) Article DOI: 10.1021/jm0102250 BindingDB Entry DOI: 10.7270/Q2TD9VHP
					More data for this Ligand-Target Pair
Proto-oncogene tyrosine-protein kinase Src (Homo sapiens (Human))	BDBM4545 (4-Phenylamino-3-quinolinecarbonitrile deriv. 2e | ...) Show SMILES COc1cc(Nc2c(cnc3cc(OCCCN4CCOCC4)c(OC)cc23)C#N)c(C)cc1Cl Show InChI InChI=1S/C26H29ClN4O4/c1-17-11-20(27)23(32-2)13-21(17)30-26-18(15-28)16-29-22-14-25(24(33-3)12-19(22)26)35-8-4-5-31-6-9-34-10-7-31/h11-14,16H,4-10H2,1-3H3,(H,29,30)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	1.20	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth-Ayerst Research					Assay Description Src kinase activity was measured in an ELISA format. IC50 is the inhibitor concentration which inhibits 50% of kinase activity that catalyzes the tra...				J Med Chem 44: 3965-77 (2001) Article DOI: 10.1021/jm0102250 BindingDB Entry DOI: 10.7270/Q2TD9VHP
					More data for this Ligand-Target Pair
Proto-oncogene tyrosine-protein kinase Src (Homo sapiens (Human))	BDBM4552 (4-[(2,4-Dichloro-5-methoxyphenyl)amino]-6-methoxy-...) Show SMILES COc1cc(Nc2c(cnc3cc(OCCCN4CCN(C)CC4)c(OC)cc23)C#N)c(Cl)cc1Cl Show InChI InChI=1S/C26H29Cl2N5O3/c1-32-6-8-33(9-7-32)5-4-10-36-25-13-21-18(11-24(25)35-3)26(17(15-29)16-30-21)31-22-14-23(34-2)20(28)12-19(22)27/h11-14,16H,4-10H2,1-3H3,(H,30,31)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE MMDB PC cid PC sid PDB UniChem Patents Similars	DrugBank Article PubMed	n/a	n/a	1.20	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth-Ayerst Research					Assay Description Src kinase activity was measured in an ELISA format. IC50 is the inhibitor concentration which inhibits 50% of kinase activity that catalyzes the tra...				J Med Chem 44: 3965-77 (2001) Article DOI: 10.1021/jm0102250 BindingDB Entry DOI: 10.7270/Q2TD9VHP
					More data for this Ligand-Target Pair
Proto-oncogene tyrosine-protein kinase Src (Homo sapiens (Human))	BDBM4559 (4-Phenylamino-3-quinolinecarbonitrile deriv. 31h |...) Show SMILES COc1cc(Nc2c(cnc3cc(OCCCN4CCCCC4)c(OC)cc23)C#N)c(Cl)cc1Cl Show InChI InChI=1S/C26H28Cl2N4O3/c1-33-23-14-22(19(27)12-20(23)28)31-26-17(15-29)16-30-21-13-25(24(34-2)11-18(21)26)35-10-6-9-32-7-4-3-5-8-32/h11-14,16H,3-10H2,1-2H3,(H,30,31)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	1.20	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth-Ayerst Research					Assay Description Src kinase activity was measured in an ELISA format. IC50 is the inhibitor concentration which inhibits 50% of kinase activity that catalyzes the tra...				J Med Chem 44: 3965-77 (2001) Article DOI: 10.1021/jm0102250 BindingDB Entry DOI: 10.7270/Q2TD9VHP
					More data for this Ligand-Target Pair
Proto-oncogene tyrosine-protein kinase Src (Homo sapiens (Human))	BDBM4550 (4-Phenylamino 3-quinolinecarbonitrile deriv. 27 | ...) Show SMILES COc1cc(Nc2c(cnc3cc(OCCCCN4CCOCC4)c(OC)cc23)C#N)c(Cl)cc1Cl Show InChI InChI=1S/C26H28Cl2N4O4/c1-33-23-14-22(19(27)12-20(23)28)31-26-17(15-29)16-30-21-13-25(24(34-2)11-18(21)26)36-8-4-3-5-32-6-9-35-10-7-32/h11-14,16H,3-10H2,1-2H3,(H,30,31)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	1.30	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth-Ayerst Research					Assay Description Src kinase activity was measured in an ELISA format. IC50 is the inhibitor concentration which inhibits 50% of kinase activity that catalyzes the tra...				J Med Chem 44: 3965-77 (2001) Article DOI: 10.1021/jm0102250 BindingDB Entry DOI: 10.7270/Q2TD9VHP
					More data for this Ligand-Target Pair
Proto-oncogene tyrosine-protein kinase Src (Homo sapiens (Human))	BDBM4554 (4-Phenylamino-3-quinolinecarbonitrile deriv. 31c |...) Show SMILES COc1cc(Nc2c(cnc3cc(OCCCN4C[C@H](C)N(C)[C@H](C)C4)c(OC)cc23)C#N)c(Cl)cc1Cl |r| Show InChI InChI=1S/C28H33Cl2N5O3/c1-17-15-35(16-18(2)34(17)3)7-6-8-38-27-11-23-20(9-26(27)37-5)28(19(13-31)14-32-23)33-24-12-25(36-4)22(30)10-21(24)29/h9-12,14,17-18H,6-8,15-16H2,1-5H3,(H,32,33)/t17-,18+	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	1.40	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth-Ayerst Research					Assay Description Src kinase activity was measured in an ELISA format. IC50 is the inhibitor concentration which inhibits 50% of kinase activity that catalyzes the tra...				J Med Chem 44: 3965-77 (2001) Article DOI: 10.1021/jm0102250 BindingDB Entry DOI: 10.7270/Q2TD9VHP
					More data for this Ligand-Target Pair
Proto-oncogene tyrosine-protein kinase Src (Homo sapiens (Human))	BDBM4558 (4-Phenylamino-3-quinolinecarbonitrile deriv. 31g |...) Show SMILES COc1cc(Nc2c(cnc3cc(OCCCN4CCCN(C)CC4)c(OC)cc23)C#N)c(Cl)cc1Cl Show InChI InChI=1S/C27H31Cl2N5O3/c1-33-6-4-7-34(10-9-33)8-5-11-37-26-14-22-19(12-25(26)36-3)27(18(16-30)17-31-22)32-23-15-24(35-2)21(29)13-20(23)28/h12-15,17H,4-11H2,1-3H3,(H,31,32)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	1.40	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth-Ayerst Research					Assay Description Src kinase activity was measured in an ELISA format. IC50 is the inhibitor concentration which inhibits 50% of kinase activity that catalyzes the tra...				J Med Chem 44: 3965-77 (2001) Article DOI: 10.1021/jm0102250 BindingDB Entry DOI: 10.7270/Q2TD9VHP
					More data for this Ligand-Target Pair
Proto-oncogene tyrosine-protein kinase Src (Homo sapiens (Human))	BDBM4542 (4-Phenylamino-3-quinolinecarbonitrile deriv. 2b | ...) Show SMILES COc1ccc(Cl)c(Nc2c(cnc3cc(OCCCN4CCOCC4)c(OC)cc23)C#N)c1 Show InChI InChI=1S/C25H27ClN4O4/c1-31-18-4-5-20(26)22(12-18)29-25-17(15-27)16-28-21-14-24(23(32-2)13-19(21)25)34-9-3-6-30-7-10-33-11-8-30/h4-5,12-14,16H,3,6-11H2,1-2H3,(H,28,29)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	1.60	n/a	n/a	n/a	n/a	7.5	30
Wyeth-Ayerst Research					Assay Description Src kinase activity was measured in an ELISA format. IC50 is the inhibitor concentration which inhibits 50% of kinase activity that catalyzes the tra...				J Med Chem 44: 3965-77 (2001) Article DOI: 10.1021/jm0102250 BindingDB Entry DOI: 10.7270/Q2TD9VHP
					More data for this Ligand-Target Pair
Proto-oncogene tyrosine-protein kinase Src (Homo sapiens (Human))	BDBM4546 (4-Phenylamino-3-quinolinecarbonitrile deriv. 2f | ...) Show SMILES COc1cc(Nc2c(cnc3cc(OCCCN4CCOCC4)c(OC)cc23)C#N)c(C)cc1C Show InChI InChI=1S/C27H32N4O4/c1-18-12-19(2)24(32-3)14-22(18)30-27-20(16-28)17-29-23-15-26(25(33-4)13-21(23)27)35-9-5-6-31-7-10-34-11-8-31/h12-15,17H,5-11H2,1-4H3,(H,29,30)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	1.70	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth-Ayerst Research					Assay Description Src kinase activity was measured in an ELISA format. IC50 is the inhibitor concentration which inhibits 50% of kinase activity that catalyzes the tra...				J Med Chem 44: 3965-77 (2001) Article DOI: 10.1021/jm0102250 BindingDB Entry DOI: 10.7270/Q2TD9VHP
					More data for this Ligand-Target Pair
Proto-oncogene tyrosine-protein kinase Src (Homo sapiens (Human))	BDBM4562 (4-Phenylamino-3-quinolinecarbonitrile deriv. 31k |...) Show SMILES COc1cc(Nc2c(cnc3cc(OCCCn4ccnn4)c(OC)cc23)C#N)c(Cl)cc1Cl Show InChI InChI=1S/C23H20Cl2N6O3/c1-32-20-11-19(16(24)9-17(20)25)29-23-14(12-26)13-27-18-10-22(21(33-2)8-15(18)23)34-7-3-5-31-6-4-28-30-31/h4,6,8-11,13H,3,5,7H2,1-2H3,(H,27,29)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	1.90	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth-Ayerst Research					Assay Description Src kinase activity was measured in an ELISA format. IC50 is the inhibitor concentration which inhibits 50% of kinase activity that catalyzes the tra...				J Med Chem 44: 3965-77 (2001) Article DOI: 10.1021/jm0102250 BindingDB Entry DOI: 10.7270/Q2TD9VHP
					More data for this Ligand-Target Pair
Melanin-concentrating hormone receptor 1 (Homo sapiens (Human))	BDBM50107733 (CHEMBL3600801) Show SMILES Clc1ccc(cc1)-c1ccc(cc1)C(=O)NCCc1ccc(CN2CCCC2)cc1 Show InChI InChI=1S/C26H27ClN2O/c27-25-13-11-23(12-14-25)22-7-9-24(10-8-22)26(30)28-16-15-20-3-5-21(6-4-20)19-29-17-1-2-18-29/h3-14H,1-2,15-19H2,(H,28,30)	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2	n/a	n/a	n/a	n/a	n/a	n/a
Boehringer Ingelheim Pharma GmbH& Co. KG Curated by ChEMBL					Assay Description Displacement of [125I]-MCH from human MCHR1 expressed in CHO/Galpha16 cell membranes by scintillation counting method				Bioorg Med Chem Lett 25: 3264-9 (2015) Article DOI: 10.1016/j.bmcl.2015.05.077 BindingDB Entry DOI: 10.7270/Q25D8TMB
					More data for this Ligand-Target Pair
Melanin-concentrating hormone receptor 1 (Homo sapiens (Human))	BDBM50107764 (CHEMBL3600807) Show SMILES Clc1ccc(cc1)-c1ccc(cc1)C(=O)NCCc1ccc(CN2CCCC2)cc1Br Show InChI InChI=1S/C26H26BrClN2O/c27-25-17-19(18-30-15-1-2-16-30)3-4-22(25)13-14-29-26(31)23-7-5-20(6-8-23)21-9-11-24(28)12-10-21/h3-12,17H,1-2,13-16,18H2,(H,29,31)	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	2	n/a	n/a	n/a	n/a	n/a	n/a
Boehringer Ingelheim Pharma GmbH& Co. KG Curated by ChEMBL					Assay Description Displacement of [125I]-MCH from human MCHR1 expressed in CHO/Galpha16 cell membranes by scintillation counting method				Bioorg Med Chem Lett 25: 3264-9 (2015) Article DOI: 10.1016/j.bmcl.2015.05.077 BindingDB Entry DOI: 10.7270/Q25D8TMB
					More data for this Ligand-Target Pair
Melanin-concentrating hormone receptor 1 (Homo sapiens (Human))	BDBM50107761 (CHEMBL3600804) Show SMILES OCCNCc1ccc(CCNC(=O)c2ccc(cc2)-c2ccc(Cl)cc2)cc1 Show InChI InChI=1S/C24H25ClN2O2/c25-23-11-9-21(10-12-23)20-5-7-22(8-6-20)24(29)27-14-13-18-1-3-19(4-2-18)17-26-15-16-28/h1-12,26,28H,13-17H2,(H,27,29)	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	2	n/a	n/a	n/a	n/a	n/a	n/a
Boehringer Ingelheim Pharma GmbH& Co. KG Curated by ChEMBL					Assay Description Displacement of [125I]-MCH from human MCHR1 expressed in CHO/Galpha16 cell membranes by scintillation counting method				Bioorg Med Chem Lett 25: 3264-9 (2015) Article DOI: 10.1016/j.bmcl.2015.05.077 BindingDB Entry DOI: 10.7270/Q25D8TMB
					More data for this Ligand-Target Pair
Melanin-concentrating hormone receptor 1 (Homo sapiens (Human))	BDBM50107760 (CHEMBL3600803) Show SMILES Clc1ccc(cc1)-c1ccc(cc1)C(=O)NCCc1ccc(CN2CCCCC2)cc1 Show InChI InChI=1S/C27H29ClN2O/c28-26-14-12-24(13-15-26)23-8-10-25(11-9-23)27(31)29-17-16-21-4-6-22(7-5-21)20-30-18-2-1-3-19-30/h4-15H,1-3,16-20H2,(H,29,31)	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	2	n/a	n/a	n/a	n/a	n/a	n/a
Boehringer Ingelheim Pharma GmbH& Co. KG Curated by ChEMBL					Assay Description Displacement of [125I]-MCH from human MCHR1 expressed in CHO/Galpha16 cell membranes by scintillation counting method				Bioorg Med Chem Lett 25: 3264-9 (2015) Article DOI: 10.1016/j.bmcl.2015.05.077 BindingDB Entry DOI: 10.7270/Q25D8TMB
					More data for this Ligand-Target Pair
Proto-oncogene tyrosine-protein kinase Src (Homo sapiens (Human))	BDBM4563 (4-Phenylamino-3-quinolinecarbonitrile deriv. 31l |...) Show SMILES COc1cc(Nc2c(cnc3cc(OCCCn4ccnc4)c(OC)cc23)C#N)c(Cl)cc1Cl Show InChI InChI=1S/C24H21Cl2N5O3/c1-32-21-11-20(17(25)9-18(21)26)30-24-15(12-27)13-29-19-10-23(22(33-2)8-16(19)24)34-7-3-5-31-6-4-28-14-31/h4,6,8-11,13-14H,3,5,7H2,1-2H3,(H,29,30)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	2.10	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth-Ayerst Research					Assay Description Src kinase activity was measured in an ELISA format. IC50 is the inhibitor concentration which inhibits 50% of kinase activity that catalyzes the tra...				J Med Chem 44: 3965-77 (2001) Article DOI: 10.1021/jm0102250 BindingDB Entry DOI: 10.7270/Q2TD9VHP
					More data for this Ligand-Target Pair
Proto-oncogene tyrosine-protein kinase Src (Homo sapiens (Human))	BDBM4565 (4-Phenylamino-3-quinolinecarbonitrile deriv. 31n |...) Show SMILES COc1cc(Nc2c(cnc3cc(OCCCN(C)CCN(C)C)c(OC)cc23)C#N)c(Cl)cc1Cl Show InChI InChI=1S/C26H31Cl2N5O3/c1-32(2)8-9-33(3)7-6-10-36-25-13-21-18(11-24(25)35-5)26(17(15-29)16-30-21)31-22-14-23(34-4)20(28)12-19(22)27/h11-14,16H,6-10H2,1-5H3,(H,30,31)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	2.30	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth-Ayerst Research					Assay Description Src kinase activity was measured in an ELISA format. IC50 is the inhibitor concentration which inhibits 50% of kinase activity that catalyzes the tra...				J Med Chem 44: 3965-77 (2001) Article DOI: 10.1021/jm0102250 BindingDB Entry DOI: 10.7270/Q2TD9VHP
					More data for this Ligand-Target Pair
Proto-oncogene tyrosine-protein kinase Src (Homo sapiens (Human))	BDBM4549 (4-Phenylamino 3-quinolinecarbonitrile deriv. 26 | ...) Show SMILES COc1cc(Nc2c(cnc3cc(OCCN4CCOCC4)c(OC)cc23)C#N)c(Cl)cc1Cl Show InChI InChI=1S/C24H24Cl2N4O4/c1-31-21-12-20(17(25)10-18(21)26)29-24-15(13-27)14-28-19-11-23(22(32-2)9-16(19)24)34-8-5-30-3-6-33-7-4-30/h9-12,14H,3-8H2,1-2H3,(H,28,29)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	2.30	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth-Ayerst Research					Assay Description Src kinase activity was measured in an ELISA format. IC50 is the inhibitor concentration which inhibits 50% of kinase activity that catalyzes the tra...				J Med Chem 44: 3965-77 (2001) Article DOI: 10.1021/jm0102250 BindingDB Entry DOI: 10.7270/Q2TD9VHP
					More data for this Ligand-Target Pair
Proto-oncogene tyrosine-protein kinase Src (Homo sapiens (Human))	BDBM4551 (4-Phenylamino-3-quinolinecarbonitrile deriv. 28 | ...) Show SMILES COc1cc(Nc2c(cnc3cc(OCCCCCN4CCOCC4)c(OC)cc23)C#N)c(Cl)cc1Cl Show InChI InChI=1S/C27H30Cl2N4O4/c1-34-24-15-23(20(28)13-21(24)29)32-27-18(16-30)17-31-22-14-26(25(35-2)12-19(22)27)37-9-5-3-4-6-33-7-10-36-11-8-33/h12-15,17H,3-11H2,1-2H3,(H,31,32)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	2.5	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth-Ayerst Research					Assay Description Src kinase activity was measured in an ELISA format. IC50 is the inhibitor concentration which inhibits 50% of kinase activity that catalyzes the tra...				J Med Chem 44: 3965-77 (2001) Article DOI: 10.1021/jm0102250 BindingDB Entry DOI: 10.7270/Q2TD9VHP
					More data for this Ligand-Target Pair
Proto-oncogene tyrosine-protein kinase Src (Homo sapiens (Human))	BDBM4534 (4-Phenylamino-3-quinolinecarbonitrile deriv. 1l | ...) Show SMILES COc1cc(Nc2c(cnc3cc(OC)c(OC)cc23)C#N)c(Cl)cc1C Show InChI InChI=1S/C20H18ClN3O3/c1-11-5-14(21)16(8-17(11)25-2)24-20-12(9-22)10-23-15-7-19(27-4)18(26-3)6-13(15)20/h5-8,10H,1-4H3,(H,23,24)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	2.90	n/a	n/a	n/a	n/a	7.5	30
Wyeth-Ayerst Research					Assay Description Src kinase activity was measured in an ELISA format. IC50 is the inhibitor concentration which inhibits 50% of kinase activity that catalyzes the tra...				J Med Chem 44: 3965-77 (2001) Article DOI: 10.1021/jm0102250 BindingDB Entry DOI: 10.7270/Q2TD9VHP
					More data for this Ligand-Target Pair
Proto-oncogene tyrosine-protein kinase Src (Homo sapiens (Human))	BDBM4530 (4-Phenylamino-3-quinolinecarbonitrile deriv. 1h | ...) Show SMILES COc1cc(Nc2c(cnc3cc(OC)c(OC)cc23)C#N)c(Br)cc1Cl Show InChI InChI=1S/C19H15BrClN3O3/c1-25-16-7-15(12(20)5-13(16)21)24-19-10(8-22)9-23-14-6-18(27-3)17(26-2)4-11(14)19/h4-7,9H,1-3H3,(H,23,24)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	3	n/a	n/a	n/a	n/a	7.5	30
Wyeth-Ayerst Research					Assay Description Src kinase activity was measured in an ELISA format. IC50 is the inhibitor concentration which inhibits 50% of kinase activity that catalyzes the tra...				J Med Chem 44: 3965-77 (2001) Article DOI: 10.1021/jm0102250 BindingDB Entry DOI: 10.7270/Q2TD9VHP
					More data for this Ligand-Target Pair
Melanin-concentrating hormone receptor 1 (Homo sapiens (Human))	BDBM50106579 (CHEMBL3601036) Show SMILES OC1CCN(Cc2ccc(NCCCc3ccc(OCc4ccccc4)nn3)cc2)CC1 Show InChI InChI=1S/C26H32N4O2/c31-25-14-17-30(18-15-25)19-21-8-10-23(11-9-21)27-16-4-7-24-12-13-26(29-28-24)32-20-22-5-2-1-3-6-22/h1-3,5-6,8-13,25,27,31H,4,7,14-20H2	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3	n/a	n/a	n/a	n/a	n/a	n/a
Boehringer Ingelheim Pharma GmbH& Co. KG Curated by ChEMBL					Assay Description Displacement of [125I-MCH] from human MCH receptor 1 expressed in CHO cell membranes by scintillation counting method				Bioorg Med Chem Lett 25: 3270-4 (2015) Article DOI: 10.1016/j.bmcl.2015.05.074 BindingDB Entry DOI: 10.7270/Q2MK6FN7
					More data for this Ligand-Target Pair
3-phosphoinositide-dependent protein kinase 1 (Homo sapiens (Human))	BDBM50316351 (2-(5-{[(2S)-2-Amino-3-(4-fluorophenyl)propyl]oxy}p...) Show SMILES COc1cc2ncc3c(N)nc(cc3c2cc1OC)-c1cncc(OC[C@@H](N)Cc2ccc(F)cc2)c1 |r| Show InChI InChI=1S/C28H26FN5O3/c1-35-26-10-22-21-9-24(34-28(31)23(21)14-33-25(22)11-27(26)36-2)17-8-20(13-32-12-17)37-15-19(30)7-16-3-5-18(29)6-4-16/h3-6,8-14,19H,7,15,30H2,1-2H3,(H2,31,34)/t19-/m0/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Inhibition of human GST-tagged-PDK1 expressed in HEK293 cells				Eur J Med Chem 45: 1379-86 (2010) Article DOI: 10.1016/j.ejmech.2009.12.036 BindingDB Entry DOI: 10.7270/Q2HD7VT5
					More data for this Ligand-Target Pair
Melanin-concentrating hormone receptor 1 (Homo sapiens (Human))	BDBM50107735 (CHEMBL3600815) Show SMILES CC(=O)NC1CCN(Cc2ccc(CCNC(=O)c3ccc(cc3)-c3ccc(F)cc3)cc2)CC1 Show InChI InChI=1S/C29H32FN3O2/c1-21(34)32-28-15-18-33(19-16-28)20-23-4-2-22(3-5-23)14-17-31-29(35)26-8-6-24(7-9-26)25-10-12-27(30)13-11-25/h2-13,28H,14-20H2,1H3,(H,31,35)(H,32,34)	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3	n/a	n/a	n/a	n/a	n/a	n/a
Boehringer Ingelheim Pharma GmbH& Co. KG Curated by ChEMBL					Assay Description Displacement of [125I]-MCH from human MCHR1 expressed in CHO/Galpha16 cell membranes by scintillation counting method				Bioorg Med Chem Lett 25: 3264-9 (2015) Article DOI: 10.1016/j.bmcl.2015.05.077 BindingDB Entry DOI: 10.7270/Q25D8TMB
					More data for this Ligand-Target Pair
Melanin-concentrating hormone receptor 1 (Homo sapiens (Human))	BDBM50106487 (CHEMBL3600970) Show SMILES Clc1ccc(cc1)-c1ccc(CCCNc2ccc(CN3CCCCC3)cc2)cc1 Show InChI InChI=1S/C27H31ClN2/c28-26-14-12-25(13-15-26)24-10-6-22(7-11-24)5-4-18-29-27-16-8-23(9-17-27)21-30-19-2-1-3-20-30/h6-17,29H,1-5,18-21H2	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3	n/a	n/a	n/a	n/a	n/a	n/a
Boehringer Ingelheim Pharma GmbH& Co. KG Curated by ChEMBL					Assay Description Displacement of [125I-MCH] from human MCH receptor 1 expressed in CHO cell membranes by scintillation counting method				Bioorg Med Chem Lett 25: 3270-4 (2015) Article DOI: 10.1016/j.bmcl.2015.05.074 BindingDB Entry DOI: 10.7270/Q2MK6FN7
					More data for this Ligand-Target Pair
Proto-oncogene tyrosine-protein kinase Src (Homo sapiens (Human))	BDBM4564 (4-Phenylamino-3-quinolinecarbonitrile deriv. 31m |...) Show SMILES COc1cc(Nc2c(cnc3cc(OCCCNCCN4CCOCC4)c(OC)cc23)C#N)c(Cl)cc1Cl Show InChI InChI=1S/C27H31Cl2N5O4/c1-35-24-15-23(20(28)13-21(24)29)33-27-18(16-30)17-32-22-14-26(25(36-2)12-19(22)27)38-9-3-4-31-5-6-34-7-10-37-11-8-34/h12-15,17,31H,3-11H2,1-2H3,(H,32,33)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	3	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth-Ayerst Research					Assay Description Src kinase activity was measured in an ELISA format. IC50 is the inhibitor concentration which inhibits 50% of kinase activity that catalyzes the tra...				J Med Chem 44: 3965-77 (2001) Article DOI: 10.1021/jm0102250 BindingDB Entry DOI: 10.7270/Q2TD9VHP
					More data for this Ligand-Target Pair
3-phosphoinositide-dependent protein kinase 1 (Homo sapiens (Human))	BDBM50316346 (2-(5-{[(2R)-2-Aminobutyl]oxy}pyridin-3-yl)-8,9-dim...) Show SMILES CC[C@@H](N)COc1cncc(c1)-c1cc2c(cnc3cc(OC)c(OC)cc23)c(N)n1 |r| Show InChI InChI=1S/C23H25N5O3/c1-4-14(24)12-31-15-5-13(9-26-10-15)19-6-16-17-7-21(29-2)22(30-3)8-20(17)27-11-18(16)23(25)28-19/h5-11,14H,4,12,24H2,1-3H3,(H2,25,28)/t14-/m1/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Inhibition of human GST-tagged-PDK1 expressed in HEK293 cells				Eur J Med Chem 45: 1379-86 (2010) Article DOI: 10.1016/j.ejmech.2009.12.036 BindingDB Entry DOI: 10.7270/Q2HD7VT5
					More data for this Ligand-Target Pair
3-phosphoinositide-dependent protein kinase 1 (Homo sapiens (Human))	BDBM50316344 (2-(5-{[(2R)-2-Aminopropyl]oxy}pyridin-3-yl)-8,9-di...) Show SMILES COc1cc2ncc3c(N)nc(cc3c2cc1OC)-c1cncc(OC[C@@H](C)N)c1 |r| Show InChI InChI=1S/C22H23N5O3/c1-12(23)11-30-14-4-13(8-25-9-14)18-5-15-16-6-20(28-2)21(29-3)7-19(16)26-10-17(15)22(24)27-18/h4-10,12H,11,23H2,1-3H3,(H2,24,27)/t12-/m1/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Inhibition of human GST-tagged-PDK1 expressed in HEK293 cells				Eur J Med Chem 45: 1379-86 (2010) Article DOI: 10.1016/j.ejmech.2009.12.036 BindingDB Entry DOI: 10.7270/Q2HD7VT5
					More data for this Ligand-Target Pair
Melanin-concentrating hormone receptor 1 (Homo sapiens (Human))	BDBM50107820 (CHEMBL3600812) Show SMILES Fc1ccc(cc1)-c1ccc(cc1)C(=O)NCCc1ccc(CN2CCCC2)cc1 Show InChI InChI=1S/C26H27FN2O/c27-25-13-11-23(12-14-25)22-7-9-24(10-8-22)26(30)28-16-15-20-3-5-21(6-4-20)19-29-17-1-2-18-29/h3-14H,1-2,15-19H2,(H,28,30)	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3	n/a	n/a	n/a	n/a	n/a	n/a
Boehringer Ingelheim Pharma GmbH& Co. KG Curated by ChEMBL					Assay Description Displacement of [125I]-MCH from human MCHR1 expressed in CHO/Galpha16 cell membranes by scintillation counting method				Bioorg Med Chem Lett 25: 3264-9 (2015) Article DOI: 10.1016/j.bmcl.2015.05.077 BindingDB Entry DOI: 10.7270/Q25D8TMB
					More data for this Ligand-Target Pair
Proto-oncogene tyrosine-protein kinase Src (Homo sapiens (Human))	BDBM4522 (4-Phenylamino-3-quinolinecarbonitrile deriv. 27 | ...) Show SMILES COc1cc2c(Nc3ccc(Cl)cc3Cl)c(cnc2cc1OCCCN1CCC(O)CC1)C#N Show InChI InChI=1S/C25H26Cl2N4O3/c1-33-23-12-19-22(13-24(23)34-10-2-7-31-8-5-18(32)6-9-31)29-15-16(14-28)25(19)30-21-4-3-17(26)11-20(21)27/h3-4,11-13,15,18,32H,2,5-10H2,1H3,(H,29,30)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.5	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth-Ayerst Research					Assay Description Src kinase activity was measured in an ELISA format. IC50 is the inhibitor concentration which inhibits 50% of kinase activity that catalyzes the tra...				J Med Chem 44: 822-33 (2001) Article DOI: 10.1021/jm000420z BindingDB Entry DOI: 10.7270/Q2Z31WVP
					More data for this Ligand-Target Pair
Proto-oncogene tyrosine-protein kinase Src (Homo sapiens (Human))	BDBM4520 (4-Phenylamino-3-quinolinecarbonitrile deriv. 25 | ...) Show SMILES COc1cc2c(Nc3ccc(Cl)cc3Cl)c(cnc2cc1OCCCN1CCOCC1)C#N Show InChI InChI=1S/C24H24Cl2N4O3/c1-31-22-12-18-21(13-23(22)33-8-2-5-30-6-9-32-10-7-30)28-15-16(14-27)24(18)29-20-4-3-17(25)11-19(20)26/h3-4,11-13,15H,2,5-10H2,1H3,(H,28,29)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	3.80	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth-Ayerst Research					Assay Description Src kinase activity was measured in an ELISA format. IC50 is the inhibitor concentration which inhibits 50% of kinase activity that catalyzes the tra...				J Med Chem 44: 822-33 (2001) Article DOI: 10.1021/jm000420z BindingDB Entry DOI: 10.7270/Q2Z31WVP
					More data for this Ligand-Target Pair
Proto-oncogene tyrosine-protein kinase Src (Homo sapiens (Human))	BDBM4520 (4-Phenylamino-3-quinolinecarbonitrile deriv. 25 | ...) Show SMILES COc1cc2c(Nc3ccc(Cl)cc3Cl)c(cnc2cc1OCCCN1CCOCC1)C#N Show InChI InChI=1S/C24H24Cl2N4O3/c1-31-22-12-18-21(13-23(22)33-8-2-5-30-6-9-32-10-7-30)28-15-16(14-27)24(18)29-20-4-3-17(25)11-19(20)26/h3-4,11-13,15H,2,5-10H2,1H3,(H,28,29)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	3.80	n/a	n/a	n/a	n/a	7.5	30
Wyeth-Ayerst Research					Assay Description Src kinase activity was measured in an ELISA format. IC50 is the inhibitor concentration which inhibits 50% of kinase activity that catalyzes the tra...				J Med Chem 44: 3965-77 (2001) Article DOI: 10.1021/jm0102250 BindingDB Entry DOI: 10.7270/Q2TD9VHP
					More data for this Ligand-Target Pair
Melanin-concentrating hormone receptor 1 (Homo sapiens (Human))	BDBM50106522 (CHEMBL3600978) Show SMILES Clc1ccc(cc1)-c1ccc(CCCNc2ccc(CN3CCCCC3)cc2)nn1 Show InChI InChI=1S/C25H29ClN4/c26-22-10-8-21(9-11-22)25-15-14-24(28-29-25)5-4-16-27-23-12-6-20(7-13-23)19-30-17-2-1-3-18-30/h6-15,27H,1-5,16-19H2	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	4	n/a	n/a	n/a	n/a	n/a	n/a
Boehringer Ingelheim Pharma GmbH& Co. KG Curated by ChEMBL					Assay Description Displacement of [125I-MCH] from human MCH receptor 1 expressed in CHO cell membranes by scintillation counting method				Bioorg Med Chem Lett 25: 3270-4 (2015) Article DOI: 10.1016/j.bmcl.2015.05.074 BindingDB Entry DOI: 10.7270/Q2MK6FN7
					More data for this Ligand-Target Pair
Melanin-concentrating hormone receptor 1 (Homo sapiens (Human))	BDBM50106583 (CHEMBL3601040) Show SMILES OCC1CCN(Cc2ccc(OCCCc3ccc(nn3)-c3ccc(Cl)cc3)cc2)CC1 Show InChI InChI=1S/C26H30ClN3O2/c27-23-7-5-22(6-8-23)26-12-9-24(28-29-26)2-1-17-32-25-10-3-20(4-11-25)18-30-15-13-21(19-31)14-16-30/h3-12,21,31H,1-2,13-19H2	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	4	n/a	n/a	n/a	n/a	n/a	n/a
Boehringer Ingelheim Pharma GmbH& Co. KG Curated by ChEMBL					Assay Description Displacement of [125I-MCH] from human MCH receptor 1 expressed in CHO cell membranes by scintillation counting method				Bioorg Med Chem Lett 25: 3270-4 (2015) Article DOI: 10.1016/j.bmcl.2015.05.074 BindingDB Entry DOI: 10.7270/Q2MK6FN7
					More data for this Ligand-Target Pair
Melanin-concentrating hormone receptor 1 (Homo sapiens (Human))	BDBM50107751 (CHEMBL3601023) Show SMILES Cc1cc(ccc1OCCN1CCC[C@H]1CO)C#Cc1ccc(cn1)-c1ccc(Cl)cc1 |r| Show InChI InChI=1S/C27H27ClN2O2/c1-20-17-21(5-13-27(20)32-16-15-30-14-2-3-26(30)19-31)4-11-25-12-8-23(18-29-25)22-6-9-24(28)10-7-22/h5-10,12-13,17-18,26,31H,2-3,14-16,19H2,1H3/t26-/m0/s1	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	4	n/a	n/a	n/a	n/a	n/a	n/a
Boehringer Ingelheim Pharma GmbH& Co. KG Curated by ChEMBL					Assay Description Displacement of [125I]-MCH from human MCHR1 expressed in CHO/Galpha16 cell membranes by scintillation counting method				Bioorg Med Chem Lett 25: 3264-9 (2015) Article DOI: 10.1016/j.bmcl.2015.05.077 BindingDB Entry DOI: 10.7270/Q25D8TMB
					More data for this Ligand-Target Pair
Melanin-concentrating hormone receptor 1 (Homo sapiens (Human))	BDBM50107749 (CHEMBL3601021) Show SMILES CC1CCN(CCOc2ccc(cc2)C#Cc2ncc(cc2F)-c2ccc(Cl)cc2)CC1 Show InChI InChI=1S/C27H26ClFN2O/c1-20-12-14-31(15-13-20)16-17-32-25-9-2-21(3-10-25)4-11-27-26(29)18-23(19-30-27)22-5-7-24(28)8-6-22/h2-3,5-10,18-20H,12-17H2,1H3	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	4	n/a	n/a	n/a	n/a	n/a	n/a
Boehringer Ingelheim Pharma GmbH& Co. KG Curated by ChEMBL					Assay Description Displacement of [125I]-MCH from human MCHR1 expressed in CHO/Galpha16 cell membranes by scintillation counting method				Bioorg Med Chem Lett 25: 3264-9 (2015) Article DOI: 10.1016/j.bmcl.2015.05.077 BindingDB Entry DOI: 10.7270/Q25D8TMB
					More data for this Ligand-Target Pair
Proto-oncogene tyrosine-protein kinase Src (Homo sapiens (Human))	BDBM4531 (4-Phenylamino-3-quinolinecarbonitrile deriv. 1i | ...) Show SMILES COc1cc(Nc2c(cnc3cc(OC)c(OC)cc23)C#N)c(C)cc1Cl Show InChI InChI=1S/C20H18ClN3O3/c1-11-5-14(21)17(25-2)7-15(11)24-20-12(9-22)10-23-16-8-19(27-4)18(26-3)6-13(16)20/h5-8,10H,1-4H3,(H,23,24)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	4	n/a	n/a	n/a	n/a	7.5	30
Wyeth-Ayerst Research					Assay Description Src kinase activity was measured in an ELISA format. IC50 is the inhibitor concentration which inhibits 50% of kinase activity that catalyzes the tra...				J Med Chem 44: 3965-77 (2001) Article DOI: 10.1021/jm0102250 BindingDB Entry DOI: 10.7270/Q2TD9VHP
					More data for this Ligand-Target Pair
Proto-oncogene tyrosine-protein kinase Src (Homo sapiens (Human))	BDBM4525 (4-Phenylamino-3-quinolinecarbonitrile deriv. 1c | ...) Show SMILES COc1cc(Nc2c(cnc3cc(OC)c(OC)cc23)C#N)c(Cl)cc1Cl Show InChI InChI=1S/C19H15Cl2N3O3/c1-25-16-7-15(12(20)5-13(16)21)24-19-10(8-22)9-23-14-6-18(27-3)17(26-2)4-11(14)19/h4-7,9H,1-3H3,(H,23,24)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	4.30	n/a	n/a	n/a	n/a	7.5	30
Wyeth-Ayerst Research					Assay Description Src kinase activity was measured in an ELISA format. IC50 is the inhibitor concentration which inhibits 50% of kinase activity that catalyzes the tra...				J Med Chem 44: 3965-77 (2001) Article DOI: 10.1021/jm0102250 BindingDB Entry DOI: 10.7270/Q2TD9VHP
					More data for this Ligand-Target Pair
Proto-oncogene tyrosine-protein kinase Src (Homo sapiens (Human))	BDBM4536 (4-Phenylamino-3-quinolinecarbonitrile deriv. 1n | ...) Show SMILES COc1cc(Nc2c(cnc3cc(OC)c(OC)cc23)C#N)c(C)cc1C Show InChI InChI=1S/C21H21N3O3/c1-12-6-13(2)18(25-3)8-16(12)24-21-14(10-22)11-23-17-9-20(27-5)19(26-4)7-15(17)21/h6-9,11H,1-5H3,(H,23,24)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	4.60	n/a	n/a	n/a	n/a	7.5	30
Wyeth-Ayerst Research					Assay Description Src kinase activity was measured in an ELISA format. IC50 is the inhibitor concentration which inhibits 50% of kinase activity that catalyzes the tra...				J Med Chem 44: 3965-77 (2001) Article DOI: 10.1021/jm0102250 BindingDB Entry DOI: 10.7270/Q2TD9VHP
					More data for this Ligand-Target Pair
Melanin-concentrating hormone receptor 1 (Homo sapiens (Human))	BDBM50107754 (CHEMBL3601017) Show SMILES Clc1ccc(cc1)-c1ccc(nc1)C#Cc1ccc(OCCN2CCCC2)c(Cl)c1 Show InChI InChI=1S/C25H22Cl2N2O/c26-22-8-5-20(6-9-22)21-7-11-23(28-18-21)10-3-19-4-12-25(24(27)17-19)30-16-15-29-13-1-2-14-29/h4-9,11-12,17-18H,1-2,13-16H2	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	5	n/a	n/a	n/a	n/a	n/a	n/a
Boehringer Ingelheim Pharma GmbH& Co. KG Curated by ChEMBL					Assay Description Displacement of [125I]-MCH from human MCHR1 expressed in CHO/Galpha16 cell membranes by scintillation counting method				Bioorg Med Chem Lett 25: 3264-9 (2015) Article DOI: 10.1016/j.bmcl.2015.05.077 BindingDB Entry DOI: 10.7270/Q25D8TMB
					More data for this Ligand-Target Pair

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