Compile Data Set for Download or QSAR

Found 202 hits with Last Name = 'babault' and Initial = 'n'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Histone-lysine N-methyltransferase EHMT2 (Homo sapiens (Human))	BDBM50446376 (CHEMBL3109630) Show SMILES COc1cc2c(cc1OCCCN1CCCC1)N=C(N)C21CCC1 |t:19| Show InChI InChI=1S/C19H27N3O2/c1-23-16-12-14-15(21-18(20)19(14)6-4-7-19)13-17(16)24-11-5-10-22-8-2-3-9-22/h12-13H,2-11H2,1H3,(H2,20,21)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid PDB UniChem Similars	PDB Article PubMed	n/a	n/a	3	n/a	n/a	n/a	n/a	n/a	n/a
Icahn School of Medicine at Mount Sinai Curated by ChEMBL					Assay Description Inhibition of G9a (unknown origin)				J Med Chem 62: 8996-9007 (2019) Article DOI: 10.1021/acs.jmedchem.9b00522 BindingDB Entry DOI: 10.7270/Q2JM2F0X
					More data for this Ligand-Target Pair				3D Structure (crystal)
Histone-lysine N-methyltransferase EHMT1 (Homo sapiens (Human))	BDBM50300029 (6,7-dimethoxy-2-(4-methyl-1,4-diazepan-1-yl)-N-(1-...) Show SMILES COc1cc2nc(nc(NC3CCN(C)CC3)c2cc1OC)N1CCCN(C)CC1 Show InChI InChI=1S/C22H34N6O2/c1-26-8-5-9-28(13-12-26)22-24-18-15-20(30-4)19(29-3)14-17(18)21(25-22)23-16-6-10-27(2)11-7-16/h14-16H,5-13H2,1-4H3,(H,23,24,25)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	4	n/a	n/a	n/a	n/a	n/a	n/a
Icahn School of Medicine at Mount Sinai Curated by ChEMBL					Assay Description Inhibition of recombinant GLP catalytic SET domain (982 to 1266 residues) (unknown origin) expressed in Escherichia coli BL21 (DE3) codon plus RIL as...				J Med Chem 60: 1876-1891 (2017) Article DOI: 10.1021/acs.jmedchem.6b01645 BindingDB Entry DOI: 10.7270/Q2ZP4947
					More data for this Ligand-Target Pair
Histone-lysine N-methyltransferase EHMT1 (Homo sapiens (Human))	BDBM50268879 (CHEMBL4094717) Show SMILES COc1cc2nc(nc(NC3CCN(C)CC3)c2cc1OC)N(C)C1CCCC1 Show InChI InChI=1S/C22H33N5O2/c1-26-11-9-15(10-12-26)23-21-17-13-19(28-3)20(29-4)14-18(17)24-22(25-21)27(2)16-7-5-6-8-16/h13-16H,5-12H2,1-4H3,(H,23,24,25)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid PDB UniChem Similars	PDB Article PubMed	n/a	n/a	4	n/a	n/a	n/a	n/a	n/a	n/a
Icahn School of Medicine at Mount Sinai Curated by ChEMBL					Assay Description Inhibition of human GLP catalytic domain (951 to 1235 residues) expressed in Escherichia coli BL21 (DE3) using biotinylated H3 (1 to 25 residues) as ...				Bioorg Med Chem 25: 4414-4423 (2017) Article DOI: 10.1016/j.bmc.2017.06.021 BindingDB Entry DOI: 10.7270/Q2X350ZG
					More data for this Ligand-Target Pair				3D Structure (crystal)
Histone-lysine N-methyltransferase EHMT1 (Homo sapiens (Human))	BDBM50268886 (CHEMBL4072211) Show SMILES CCCN(C)c1nc(NC2CCN(C)CC2)c2cc(OC)c(OC)cc2n1 Show InChI InChI=1S/C20H31N5O2/c1-6-9-25(3)20-22-16-13-18(27-5)17(26-4)12-15(16)19(23-20)21-14-7-10-24(2)11-8-14/h12-14H,6-11H2,1-5H3,(H,21,22,23)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid PDB UniChem Similars	PDB Article PubMed	n/a	n/a	5	n/a	n/a	n/a	n/a	n/a	n/a
Icahn School of Medicine at Mount Sinai Curated by ChEMBL					Assay Description Inhibition of human GLP catalytic domain (951 to 1235 residues) expressed in Escherichia coli BL21 (DE3) using biotinylated H3 (1 to 25 residues) as ...				Bioorg Med Chem 25: 4414-4423 (2017) Article DOI: 10.1016/j.bmc.2017.06.021 BindingDB Entry DOI: 10.7270/Q2X350ZG
					More data for this Ligand-Target Pair				3D Structure (crystal)
Histone-lysine N-methyltransferase EHMT1 (Homo sapiens (Human))	BDBM50268910 (CHEMBL4066769) Show SMILES COc1cc2nc(cc(NC3CCN(C)CC3)c2cc1OC)N1CCOCC1 Show InChI InChI=1S/C21H30N4O3/c1-24-6-4-15(5-7-24)22-18-14-21(25-8-10-28-11-9-25)23-17-13-20(27-3)19(26-2)12-16(17)18/h12-15H,4-11H2,1-3H3,(H,22,23)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	6	n/a	n/a	n/a	n/a	n/a	n/a
Icahn School of Medicine at Mount Sinai Curated by ChEMBL					Assay Description Inhibition of human GLP catalytic domain (951 to 1235 residues) expressed in Escherichia coli BL21 (DE3) using biotinylated H3 (1 to 25 residues) as ...				Bioorg Med Chem 25: 4414-4423 (2017) Article DOI: 10.1016/j.bmc.2017.06.021 BindingDB Entry DOI: 10.7270/Q2X350ZG
					More data for this Ligand-Target Pair
Histone-lysine N-methyltransferase EHMT1 (Homo sapiens (Human))	BDBM50268871 (CHEMBL4100004) Show SMILES COc1cc2nc(nc(NC3CCN(C)CC3)c2cc1OC)N(C)C1CCCCC1 Show InChI InChI=1S/C23H35N5O2/c1-27-12-10-16(11-13-27)24-22-18-14-20(29-3)21(30-4)15-19(18)25-23(26-22)28(2)17-8-6-5-7-9-17/h14-17H,5-13H2,1-4H3,(H,24,25,26)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	6	n/a	n/a	n/a	n/a	n/a	n/a
Icahn School of Medicine at Mount Sinai Curated by ChEMBL					Assay Description Inhibition of human GLP catalytic domain (951 to 1235 residues) expressed in Escherichia coli BL21 (DE3) using biotinylated H3 (1 to 25 residues) as ...				Bioorg Med Chem 25: 4414-4423 (2017) Article DOI: 10.1016/j.bmc.2017.06.021 BindingDB Entry DOI: 10.7270/Q2X350ZG
					More data for this Ligand-Target Pair
Histone-lysine N-methyltransferase EHMT1 (Homo sapiens (Human))	BDBM50501525 (CHEMBL4086403) Show SMILES CCCCCCNc1nc(NC2CCN(C)CC2)c2cc(OC)c(OC)cc2n1 Show InChI InChI=1S/C22H35N5O2/c1-5-6-7-8-11-23-22-25-18-15-20(29-4)19(28-3)14-17(18)21(26-22)24-16-9-12-27(2)13-10-16/h14-16H,5-13H2,1-4H3,(H2,23,24,25,26)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid PDB UniChem	PDB Article PubMed	n/a	n/a	7	n/a	n/a	n/a	n/a	n/a	n/a
Icahn School of Medicine at Mount Sinai Curated by ChEMBL					Assay Description Inhibition of recombinant GLP catalytic SET domain (982 to 1266 residues) (unknown origin) expressed in Escherichia coli BL21 (DE3) codon plus RIL as...				J Med Chem 60: 1876-1891 (2017) Article DOI: 10.1021/acs.jmedchem.6b01645 BindingDB Entry DOI: 10.7270/Q2ZP4947
					More data for this Ligand-Target Pair				3D Structure (crystal)
Histone-lysine N-methyltransferase EHMT2 (Homo sapiens (Human))	BDBM50300029 (6,7-dimethoxy-2-(4-methyl-1,4-diazepan-1-yl)-N-(1-...) Show SMILES COc1cc2nc(nc(NC3CCN(C)CC3)c2cc1OC)N1CCCN(C)CC1 Show InChI InChI=1S/C22H34N6O2/c1-26-8-5-9-28(13-12-26)22-24-18-15-20(30-4)19(29-3)14-17(18)21(25-22)23-16-6-10-27(2)11-7-16/h14-16H,5-13H2,1-4H3,(H,23,24,25)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	9	n/a	n/a	n/a	n/a	n/a	n/a
Icahn School of Medicine at Mount Sinai Curated by ChEMBL					Assay Description Inhibition of recombinant G9a catalytic SET domain (913 to 1193 residues) (unknown origin) expressed in Escherichia coli BL21 (DE3) codon plus RIL as...				J Med Chem 60: 1876-1891 (2017) Article DOI: 10.1021/acs.jmedchem.6b01645 BindingDB Entry DOI: 10.7270/Q2ZP4947
					More data for this Ligand-Target Pair
Histone-lysine N-methyltransferase EHMT1 (Homo sapiens (Human))	BDBM50268909 (CHEMBL4088064) Show SMILES CCCCCCNc1cc(NC2CCN(C)CC2)c2cc(OC)c(OC)cc2n1 Show InChI InChI=1S/C23H36N4O2/c1-5-6-7-8-11-24-23-16-20(25-17-9-12-27(2)13-10-17)18-14-21(28-3)22(29-4)15-19(18)26-23/h14-17H,5-13H2,1-4H3,(H2,24,25,26)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	11	n/a	n/a	n/a	n/a	n/a	n/a
Icahn School of Medicine at Mount Sinai Curated by ChEMBL					Assay Description Inhibition of human GLP catalytic domain (951 to 1235 residues) expressed in Escherichia coli BL21 (DE3) using biotinylated H3 (1 to 25 residues) as ...				Bioorg Med Chem 25: 4414-4423 (2017) Article DOI: 10.1016/j.bmc.2017.06.021 BindingDB Entry DOI: 10.7270/Q2X350ZG
					More data for this Ligand-Target Pair
Histone-lysine N-methyltransferase EHMT1 (Homo sapiens (Human))	BDBM50501520 (CHEMBL4085546) Show SMILES CCCN1CCC(CC1)Nc1nc(nc2cc(OC)c(OC)cc12)N1CCOCC1 Show InChI InChI=1S/C22H33N5O3/c1-4-7-26-8-5-16(6-9-26)23-21-17-14-19(28-2)20(29-3)15-18(17)24-22(25-21)27-10-12-30-13-11-27/h14-16H,4-13H2,1-3H3,(H,23,24,25)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	11	n/a	n/a	n/a	n/a	n/a	n/a
Icahn School of Medicine at Mount Sinai Curated by ChEMBL					Assay Description Inhibition of recombinant GLP catalytic SET domain (982 to 1266 residues) (unknown origin) expressed in Escherichia coli BL21 (DE3) codon plus RIL as...				J Med Chem 60: 1876-1891 (2017) Article DOI: 10.1021/acs.jmedchem.6b01645 BindingDB Entry DOI: 10.7270/Q2ZP4947
					More data for this Ligand-Target Pair
Histone-lysine N-methyltransferase EHMT1 (Homo sapiens (Human))	BDBM50300034 (6,7-Dimethoxy-N2,N2-dimethyl-N4-(1-methylpiperidin...) Show SMILES COc1cc2nc(nc(NC3CCN(C)CC3)c2cc1OC)N(C)C Show InChI InChI=1S/C18H27N5O2/c1-22(2)18-20-14-11-16(25-5)15(24-4)10-13(14)17(21-18)19-12-6-8-23(3)9-7-12/h10-12H,6-9H2,1-5H3,(H,19,20,21)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	11	n/a	n/a	n/a	n/a	n/a	n/a
Icahn School of Medicine at Mount Sinai Curated by ChEMBL					Assay Description Inhibition of human GLP catalytic domain (951 to 1235 residues) expressed in Escherichia coli BL21 (DE3) using biotinylated H3 (1 to 25 residues) as ...				Bioorg Med Chem 25: 4414-4423 (2017) Article DOI: 10.1016/j.bmc.2017.06.021 BindingDB Entry DOI: 10.7270/Q2X350ZG
					More data for this Ligand-Target Pair
Histone-lysine N-methyltransferase EHMT1 (Homo sapiens (Human))	BDBM50300031 (6,7-Dimethoxy-N-(1-methylpiperidin-4-yl)-2-(piperi...) Show SMILES COc1cc2nc(nc(NC3CCN(C)CC3)c2cc1OC)N1CCCCC1 Show InChI InChI=1S/C21H31N5O2/c1-25-11-7-15(8-12-25)22-20-16-13-18(27-2)19(28-3)14-17(16)23-21(24-20)26-9-5-4-6-10-26/h13-15H,4-12H2,1-3H3,(H,22,23,24)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	12	n/a	n/a	n/a	n/a	n/a	n/a
Icahn School of Medicine at Mount Sinai Curated by ChEMBL					Assay Description Inhibition of recombinant GLP catalytic SET domain (982 to 1266 residues) (unknown origin) expressed in Escherichia coli BL21 (DE3) codon plus RIL as...				J Med Chem 60: 1876-1891 (2017) Article DOI: 10.1021/acs.jmedchem.6b01645 BindingDB Entry DOI: 10.7270/Q2ZP4947
					More data for this Ligand-Target Pair
Histone-lysine N-methyltransferase EHMT1 (Homo sapiens (Human))	BDBM50501523 (CHEMBL4063569) Show SMILES COc1cc2nc(nc(NC3CCN(C)CC3)c2cc1OC)N1CCCC1 Show InChI InChI=1S/C20H29N5O2/c1-24-10-6-14(7-11-24)21-19-15-12-17(26-2)18(27-3)13-16(15)22-20(23-19)25-8-4-5-9-25/h12-14H,4-11H2,1-3H3,(H,21,22,23)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	12	n/a	n/a	n/a	n/a	n/a	n/a
Icahn School of Medicine at Mount Sinai Curated by ChEMBL					Assay Description Inhibition of recombinant GLP catalytic SET domain (982 to 1266 residues) (unknown origin) expressed in Escherichia coli BL21 (DE3) codon plus RIL as...				J Med Chem 60: 1876-1891 (2017) Article DOI: 10.1021/acs.jmedchem.6b01645 BindingDB Entry DOI: 10.7270/Q2ZP4947
					More data for this Ligand-Target Pair
Histone-lysine N-methyltransferase EHMT1 (Homo sapiens (Human))	BDBM50501518 (CHEMBL4093293) Show SMILES COc1cc2nc(nc(NC3CCN(CC3)C3CC3)c2cc1OC)N1CCOCC1 Show InChI InChI=1S/C22H31N5O3/c1-28-19-13-17-18(14-20(19)29-2)24-22(27-9-11-30-12-10-27)25-21(17)23-15-5-7-26(8-6-15)16-3-4-16/h13-16H,3-12H2,1-2H3,(H,23,24,25)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	12	n/a	n/a	n/a	n/a	n/a	n/a
Icahn School of Medicine at Mount Sinai Curated by ChEMBL					Assay Description Inhibition of recombinant GLP catalytic SET domain (982 to 1266 residues) (unknown origin) expressed in Escherichia coli BL21 (DE3) codon plus RIL as...				J Med Chem 60: 1876-1891 (2017) Article DOI: 10.1021/acs.jmedchem.6b01645 BindingDB Entry DOI: 10.7270/Q2ZP4947
					More data for this Ligand-Target Pair
Histone-lysine N-methyltransferase EHMT1 (Homo sapiens (Human))	BDBM50300032 (6,7-Dimethoxy-N-(1-methylpiperidin-4-yl)-2-morphol...) Show SMILES COc1cc2nc(nc(NC3CCN(C)CC3)c2cc1OC)N1CCOCC1 Show InChI InChI=1S/C20H29N5O3/c1-24-6-4-14(5-7-24)21-19-15-12-17(26-2)18(27-3)13-16(15)22-20(23-19)25-8-10-28-11-9-25/h12-14H,4-11H2,1-3H3,(H,21,22,23)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid PDB UniChem Similars	PDB Article PubMed	n/a	n/a	13	n/a	n/a	n/a	n/a	n/a	n/a
Icahn School of Medicine at Mount Sinai Curated by ChEMBL					Assay Description Inhibition of recombinant GLP catalytic SET domain (982 to 1266 residues) (unknown origin) expressed in Escherichia coli BL21 (DE3) codon plus RIL as...				J Med Chem 60: 1876-1891 (2017) Article DOI: 10.1021/acs.jmedchem.6b01645 BindingDB Entry DOI: 10.7270/Q2ZP4947
					More data for this Ligand-Target Pair				3D Structure (crystal)
Histone-lysine N-methyltransferase EHMT1 (Homo sapiens (Human))	BDBM50501519 (CHEMBL4072569) Show SMILES COc1cc2nc(nc(NC3CCN(CC3)C(C)C)c2cc1OC)N1CCOCC1 Show InChI InChI=1S/C22H33N5O3/c1-15(2)26-7-5-16(6-8-26)23-21-17-13-19(28-3)20(29-4)14-18(17)24-22(25-21)27-9-11-30-12-10-27/h13-16H,5-12H2,1-4H3,(H,23,24,25)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	15	n/a	n/a	n/a	n/a	n/a	n/a
Icahn School of Medicine at Mount Sinai Curated by ChEMBL					Assay Description Inhibition of recombinant GLP catalytic SET domain (982 to 1266 residues) (unknown origin) expressed in Escherichia coli BL21 (DE3) codon plus RIL as...				J Med Chem 60: 1876-1891 (2017) Article DOI: 10.1021/acs.jmedchem.6b01645 BindingDB Entry DOI: 10.7270/Q2ZP4947
					More data for this Ligand-Target Pair
Histone-lysine N-methyltransferase EHMT1 (Homo sapiens (Human))	BDBM50501533 (CHEMBL4097286) Show SMILES COc1cc2nc(nc(NC3CCN(C)CC3)c2cc1OC)N1CCCCCC1 Show InChI InChI=1S/C22H33N5O2/c1-26-12-8-16(9-13-26)23-21-17-14-19(28-2)20(29-3)15-18(17)24-22(25-21)27-10-6-4-5-7-11-27/h14-16H,4-13H2,1-3H3,(H,23,24,25)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	16	n/a	n/a	n/a	n/a	n/a	n/a
Icahn School of Medicine at Mount Sinai Curated by ChEMBL					Assay Description Inhibition of recombinant GLP catalytic SET domain (982 to 1266 residues) (unknown origin) expressed in Escherichia coli BL21 (DE3) codon plus RIL as...				J Med Chem 60: 1876-1891 (2017) Article DOI: 10.1021/acs.jmedchem.6b01645 BindingDB Entry DOI: 10.7270/Q2ZP4947
					More data for this Ligand-Target Pair
Histone-lysine N-methyltransferase EHMT1 (Homo sapiens (Human))	BDBM50268880 (CHEMBL4074209) Show SMILES COc1cc2nc(nc(NC3CCN(C)CC3)c2cc1OC)N(C)C1CCC1 Show InChI InChI=1S/C21H31N5O2/c1-25-10-8-14(9-11-25)22-20-16-12-18(27-3)19(28-4)13-17(16)23-21(24-20)26(2)15-6-5-7-15/h12-15H,5-11H2,1-4H3,(H,22,23,24)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	17	n/a	n/a	n/a	n/a	n/a	n/a
Icahn School of Medicine at Mount Sinai Curated by ChEMBL					Assay Description Inhibition of human GLP catalytic domain (951 to 1235 residues) expressed in Escherichia coli BL21 (DE3) using biotinylated H3 (1 to 25 residues) as ...				Bioorg Med Chem 25: 4414-4423 (2017) Article DOI: 10.1016/j.bmc.2017.06.021 BindingDB Entry DOI: 10.7270/Q2X350ZG
					More data for this Ligand-Target Pair
Histone-lysine N-methyltransferase EHMT1 (Homo sapiens (Human))	BDBM50501522 (CHEMBL4081938) Show SMILES CCCCCCN(C)c1nc(NC2CCN(C)CC2)c2cc(OC)c(OC)cc2n1 Show InChI InChI=1S/C23H37N5O2/c1-6-7-8-9-12-28(3)23-25-19-16-21(30-5)20(29-4)15-18(19)22(26-23)24-17-10-13-27(2)14-11-17/h15-17H,6-14H2,1-5H3,(H,24,25,26)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	18	n/a	n/a	n/a	n/a	n/a	n/a
Icahn School of Medicine at Mount Sinai Curated by ChEMBL					Assay Description Inhibition of recombinant GLP catalytic SET domain (982 to 1266 residues) (unknown origin) expressed in Escherichia coli BL21 (DE3) codon plus RIL as...				J Med Chem 60: 1876-1891 (2017) Article DOI: 10.1021/acs.jmedchem.6b01645 BindingDB Entry DOI: 10.7270/Q2ZP4947
					More data for this Ligand-Target Pair
Histone-lysine N-methyltransferase EHMT1 (Homo sapiens (Human))	BDBM50268894 (CHEMBL4092975) Show SMILES CCN(C)c1nc(NC2CCN(C)CC2)c2cc(OC)c(OC)cc2n1 Show InChI InChI=1S/C19H29N5O2/c1-6-24(3)19-21-15-12-17(26-5)16(25-4)11-14(15)18(22-19)20-13-7-9-23(2)10-8-13/h11-13H,6-10H2,1-5H3,(H,20,21,22)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	18	n/a	n/a	n/a	n/a	n/a	n/a
Icahn School of Medicine at Mount Sinai Curated by ChEMBL					Assay Description Inhibition of human GLP catalytic domain (951 to 1235 residues) expressed in Escherichia coli BL21 (DE3) using biotinylated H3 (1 to 25 residues) as ...				Bioorg Med Chem 25: 4414-4423 (2017) Article DOI: 10.1016/j.bmc.2017.06.021 BindingDB Entry DOI: 10.7270/Q2X350ZG
					More data for this Ligand-Target Pair
Histone-lysine N-methyltransferase EHMT1 (Homo sapiens (Human))	BDBM50268885 (CHEMBL4084508) Show SMILES COc1cc2nc(nc(NC3CCN(C)CC3)c2cc1OC)N(C)C(C)C Show InChI InChI=1S/C20H31N5O2/c1-13(2)25(4)20-22-16-12-18(27-6)17(26-5)11-15(16)19(23-20)21-14-7-9-24(3)10-8-14/h11-14H,7-10H2,1-6H3,(H,21,22,23)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	18	n/a	n/a	n/a	n/a	n/a	n/a
Icahn School of Medicine at Mount Sinai Curated by ChEMBL					Assay Description Inhibition of human GLP catalytic domain (951 to 1235 residues) expressed in Escherichia coli BL21 (DE3) using biotinylated H3 (1 to 25 residues) as ...				Bioorg Med Chem 25: 4414-4423 (2017) Article DOI: 10.1016/j.bmc.2017.06.021 BindingDB Entry DOI: 10.7270/Q2X350ZG
					More data for this Ligand-Target Pair
Histone-lysine N-methyltransferase EHMT1 (Homo sapiens (Human))	BDBM50268867 (CHEMBL4069640) Show SMILES COc1cc2nc(nc(NC3CCN(C)CC3)c2cc1OC)N(C)CCO Show InChI InChI=1S/C19H29N5O3/c1-23-7-5-13(6-8-23)20-18-14-11-16(26-3)17(27-4)12-15(14)21-19(22-18)24(2)9-10-25/h11-13,25H,5-10H2,1-4H3,(H,20,21,22)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	20	n/a	n/a	n/a	n/a	n/a	n/a
Icahn School of Medicine at Mount Sinai Curated by ChEMBL					Assay Description Inhibition of human GLP catalytic domain (951 to 1235 residues) expressed in Escherichia coli BL21 (DE3) using biotinylated H3 (1 to 25 residues) as ...				Bioorg Med Chem 25: 4414-4423 (2017) Article DOI: 10.1016/j.bmc.2017.06.021 BindingDB Entry DOI: 10.7270/Q2X350ZG
					More data for this Ligand-Target Pair
Histone-lysine N-methyltransferase EHMT1 (Homo sapiens (Human))	BDBM50268908 (CHEMBL4063767) Show SMILES CCCN(CC)c1nc(NC2CCN(C)CC2)c2cc(OC)c(OC)cc2n1 Show InChI InChI=1S/C21H33N5O2/c1-6-10-26(7-2)21-23-17-14-19(28-5)18(27-4)13-16(17)20(24-21)22-15-8-11-25(3)12-9-15/h13-15H,6-12H2,1-5H3,(H,22,23,24)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	20	n/a	n/a	n/a	n/a	n/a	n/a
Icahn School of Medicine at Mount Sinai Curated by ChEMBL					Assay Description Inhibition of human GLP catalytic domain (951 to 1235 residues) expressed in Escherichia coli BL21 (DE3) using biotinylated H3 (1 to 25 residues) as ...				Bioorg Med Chem 25: 4414-4423 (2017) Article DOI: 10.1016/j.bmc.2017.06.021 BindingDB Entry DOI: 10.7270/Q2X350ZG
					More data for this Ligand-Target Pair
Histone-lysine N-methyltransferase EHMT1 (Homo sapiens (Human))	BDBM50268865 (CHEMBL4068291) Show SMILES COc1cc2nc(nc(NC3CCN(C)CC3)c2cc1OC)N(C)CC1CCCCC1 Show InChI InChI=1S/C24H37N5O2/c1-28-12-10-18(11-13-28)25-23-19-14-21(30-3)22(31-4)15-20(19)26-24(27-23)29(2)16-17-8-6-5-7-9-17/h14-15,17-18H,5-13,16H2,1-4H3,(H,25,26,27)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	20	n/a	n/a	n/a	n/a	n/a	n/a
Icahn School of Medicine at Mount Sinai Curated by ChEMBL					Assay Description Inhibition of human GLP catalytic domain (951 to 1235 residues) expressed in Escherichia coli BL21 (DE3) using biotinylated H3 (1 to 25 residues) as ...				Bioorg Med Chem 25: 4414-4423 (2017) Article DOI: 10.1016/j.bmc.2017.06.021 BindingDB Entry DOI: 10.7270/Q2X350ZG
					More data for this Ligand-Target Pair
Histone-lysine N-methyltransferase EHMT1 (Homo sapiens (Human))	BDBM50300033 (CHEMBL585180 | N2,N2-diethyl-6,7-dimethoxy-N4-(1-m...) Show SMILES CCN(CC)c1nc(NC2CCN(C)CC2)c2cc(OC)c(OC)cc2n1 Show InChI InChI=1S/C20H31N5O2/c1-6-25(7-2)20-22-16-13-18(27-5)17(26-4)12-15(16)19(23-20)21-14-8-10-24(3)11-9-14/h12-14H,6-11H2,1-5H3,(H,21,22,23)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	23	n/a	n/a	n/a	n/a	n/a	n/a
Icahn School of Medicine at Mount Sinai Curated by ChEMBL					Assay Description Inhibition of human GLP catalytic domain (951 to 1235 residues) expressed in Escherichia coli BL21 (DE3) using biotinylated H3 (1 to 25 residues) as ...				Bioorg Med Chem 25: 4414-4423 (2017) Article DOI: 10.1016/j.bmc.2017.06.021 BindingDB Entry DOI: 10.7270/Q2X350ZG
					More data for this Ligand-Target Pair
Histone-lysine N-methyltransferase EHMT1 (Homo sapiens (Human))	BDBM50268907 (CHEMBL4105129) Show SMILES CCCCN(CC)c1nc(NC2CCN(C)CC2)c2cc(OC)c(OC)cc2n1 Show InChI InChI=1S/C22H35N5O2/c1-6-8-11-27(7-2)22-24-18-15-20(29-5)19(28-4)14-17(18)21(25-22)23-16-9-12-26(3)13-10-16/h14-16H,6-13H2,1-5H3,(H,23,24,25)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Patents	Article PubMed	n/a	n/a	23	n/a	n/a	n/a	n/a	n/a	n/a
Icahn School of Medicine at Mount Sinai Curated by ChEMBL					Assay Description Inhibition of human GLP catalytic domain (951 to 1235 residues) expressed in Escherichia coli BL21 (DE3) using biotinylated H3 (1 to 25 residues) as ...				Bioorg Med Chem 25: 4414-4423 (2017) Article DOI: 10.1016/j.bmc.2017.06.021 BindingDB Entry DOI: 10.7270/Q2X350ZG
					More data for this Ligand-Target Pair
Histone-lysine N-methyltransferase EHMT1 (Homo sapiens (Human))	BDBM50268898 (CHEMBL4093972) Show SMILES COc1cc2nc(NCC(C)(C)C)nc(NC3CCN(C)CC3)c2cc1OC Show InChI InChI=1S/C21H33N5O2/c1-21(2,3)13-22-20-24-16-12-18(28-6)17(27-5)11-15(16)19(25-20)23-14-7-9-26(4)10-8-14/h11-12,14H,7-10,13H2,1-6H3,(H2,22,23,24,25)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	24	n/a	n/a	n/a	n/a	n/a	n/a
Icahn School of Medicine at Mount Sinai Curated by ChEMBL					Assay Description Inhibition of human GLP catalytic domain (951 to 1235 residues) expressed in Escherichia coli BL21 (DE3) using biotinylated H3 (1 to 25 residues) as ...				Bioorg Med Chem 25: 4414-4423 (2017) Article DOI: 10.1016/j.bmc.2017.06.021 BindingDB Entry DOI: 10.7270/Q2X350ZG
					More data for this Ligand-Target Pair
Histone-lysine N-methyltransferase EHMT1 (Homo sapiens (Human))	BDBM50268869 (CHEMBL4075387) Show SMILES COc1cc2nc(nc(NC3CCN(C)CC3)c2cc1OC)N(C)CCN(C)C Show InChI InChI=1S/C21H34N6O2/c1-25(2)11-12-27(4)21-23-17-14-19(29-6)18(28-5)13-16(17)20(24-21)22-15-7-9-26(3)10-8-15/h13-15H,7-12H2,1-6H3,(H,22,23,24)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	24	n/a	n/a	n/a	n/a	n/a	n/a
Icahn School of Medicine at Mount Sinai Curated by ChEMBL					Assay Description Inhibition of human GLP catalytic domain (951 to 1235 residues) expressed in Escherichia coli BL21 (DE3) using biotinylated H3 (1 to 25 residues) as ...				Bioorg Med Chem 25: 4414-4423 (2017) Article DOI: 10.1016/j.bmc.2017.06.021 BindingDB Entry DOI: 10.7270/Q2X350ZG
					More data for this Ligand-Target Pair
Histone-lysine N-methyltransferase EHMT1 (Homo sapiens (Human))	BDBM50501521 (CHEMBL4063977) Show SMILES CCN1CCC(CC1)Nc1nc(nc2cc(OC)c(OC)cc12)N1CCOCC1 Show InChI InChI=1S/C21H31N5O3/c1-4-25-7-5-15(6-8-25)22-20-16-13-18(27-2)19(28-3)14-17(16)23-21(24-20)26-9-11-29-12-10-26/h13-15H,4-12H2,1-3H3,(H,22,23,24)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	26	n/a	n/a	n/a	n/a	n/a	n/a
Icahn School of Medicine at Mount Sinai Curated by ChEMBL					Assay Description Inhibition of recombinant GLP catalytic SET domain (982 to 1266 residues) (unknown origin) expressed in Escherichia coli BL21 (DE3) codon plus RIL as...				J Med Chem 60: 1876-1891 (2017) Article DOI: 10.1021/acs.jmedchem.6b01645 BindingDB Entry DOI: 10.7270/Q2ZP4947
					More data for this Ligand-Target Pair
Histone-lysine N-methyltransferase EHMT1 (Homo sapiens (Human))	BDBM50268896 (CHEMBL4104425) Show SMILES COc1cc2nc(NCCCCC(C)C)nc(NC3CCN(C)CC3)c2cc1OC Show InChI InChI=1S/C23H37N5O2/c1-16(2)8-6-7-11-24-23-26-19-15-21(30-5)20(29-4)14-18(19)22(27-23)25-17-9-12-28(3)13-10-17/h14-17H,6-13H2,1-5H3,(H2,24,25,26,27)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	27	n/a	n/a	n/a	n/a	n/a	n/a
Icahn School of Medicine at Mount Sinai Curated by ChEMBL					Assay Description Inhibition of human GLP catalytic domain (951 to 1235 residues) expressed in Escherichia coli BL21 (DE3) using biotinylated H3 (1 to 25 residues) as ...				Bioorg Med Chem 25: 4414-4423 (2017) Article DOI: 10.1016/j.bmc.2017.06.021 BindingDB Entry DOI: 10.7270/Q2X350ZG
					More data for this Ligand-Target Pair
Histone-lysine N-methyltransferase EHMT1 (Homo sapiens (Human))	BDBM50501526 (CHEMBL4099939) Show SMILES CCCCCN(C)c1nc(NC2CCN(C)CC2)c2cc(OC)c(OC)cc2n1 Show InChI InChI=1S/C22H35N5O2/c1-6-7-8-11-27(3)22-24-18-15-20(29-5)19(28-4)14-17(18)21(25-22)23-16-9-12-26(2)13-10-16/h14-16H,6-13H2,1-5H3,(H,23,24,25)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	28	n/a	n/a	n/a	n/a	n/a	n/a
Icahn School of Medicine at Mount Sinai Curated by ChEMBL					Assay Description Inhibition of recombinant GLP catalytic SET domain (982 to 1266 residues) (unknown origin) expressed in Escherichia coli BL21 (DE3) codon plus RIL as...				J Med Chem 60: 1876-1891 (2017) Article DOI: 10.1021/acs.jmedchem.6b01645 BindingDB Entry DOI: 10.7270/Q2ZP4947
					More data for this Ligand-Target Pair
Histone-lysine N-methyltransferase EHMT1 (Homo sapiens (Human))	BDBM50268911 (CHEMBL4064559) Show SMILES COc1cc2nc(nc(NC3CCN(C)CC3)c2cc1OC)N(C)CC(C)C Show InChI InChI=1S/C21H33N5O2/c1-14(2)13-26(4)21-23-17-12-19(28-6)18(27-5)11-16(17)20(24-21)22-15-7-9-25(3)10-8-15/h11-12,14-15H,7-10,13H2,1-6H3,(H,22,23,24)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	28	n/a	n/a	n/a	n/a	n/a	n/a
Icahn School of Medicine at Mount Sinai Curated by ChEMBL					Assay Description Inhibition of human GLP catalytic domain (951 to 1235 residues) expressed in Escherichia coli BL21 (DE3) using biotinylated H3 (1 to 25 residues) as ...				Bioorg Med Chem 25: 4414-4423 (2017) Article DOI: 10.1016/j.bmc.2017.06.021 BindingDB Entry DOI: 10.7270/Q2X350ZG
					More data for this Ligand-Target Pair
Histone-lysine N-methyltransferase EHMT1 (Homo sapiens (Human))	BDBM50501524 (CHEMBL4092930) Show SMILES COc1cc2c(NC3CCN(C)CC3)nc(nc2cc1C)N1CCOCC1 Show InChI InChI=1S/C20H29N5O2/c1-14-12-17-16(13-18(14)26-3)19(21-15-4-6-24(2)7-5-15)23-20(22-17)25-8-10-27-11-9-25/h12-13,15H,4-11H2,1-3H3,(H,21,22,23)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	29	n/a	n/a	n/a	n/a	n/a	n/a
Icahn School of Medicine at Mount Sinai Curated by ChEMBL					Assay Description Inhibition of recombinant GLP catalytic SET domain (982 to 1266 residues) (unknown origin) expressed in Escherichia coli BL21 (DE3) codon plus RIL as...				J Med Chem 60: 1876-1891 (2017) Article DOI: 10.1021/acs.jmedchem.6b01645 BindingDB Entry DOI: 10.7270/Q2ZP4947
					More data for this Ligand-Target Pair
Histone-lysine N-methyltransferase EHMT1 (Homo sapiens (Human))	BDBM50268881 (CHEMBL4102467) Show SMILES COc1cc2nc(nc(NC3CCN(C)CC3)c2cc1OC)N(C)C1CC1 Show InChI InChI=1S/C20H29N5O2/c1-24-9-7-13(8-10-24)21-19-15-11-17(26-3)18(27-4)12-16(15)22-20(23-19)25(2)14-5-6-14/h11-14H,5-10H2,1-4H3,(H,21,22,23)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	30	n/a	n/a	n/a	n/a	n/a	n/a
Icahn School of Medicine at Mount Sinai Curated by ChEMBL					Assay Description Inhibition of human GLP catalytic domain (951 to 1235 residues) expressed in Escherichia coli BL21 (DE3) using biotinylated H3 (1 to 25 residues) as ...				Bioorg Med Chem 25: 4414-4423 (2017) Article DOI: 10.1016/j.bmc.2017.06.021 BindingDB Entry DOI: 10.7270/Q2X350ZG
					More data for this Ligand-Target Pair
Histone-lysine N-methyltransferase EHMT2 (Homo sapiens (Human))	BDBM50300031 (6,7-Dimethoxy-N-(1-methylpiperidin-4-yl)-2-(piperi...) Show SMILES COc1cc2nc(nc(NC3CCN(C)CC3)c2cc1OC)N1CCCCC1 Show InChI InChI=1S/C21H31N5O2/c1-25-11-7-15(8-12-25)22-20-16-13-18(27-2)19(28-3)14-17(16)23-21(24-20)26-9-5-4-6-10-26/h13-15H,4-12H2,1-3H3,(H,22,23,24)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	31	n/a	n/a	n/a	n/a	n/a	n/a
Icahn School of Medicine at Mount Sinai Curated by ChEMBL					Assay Description Inhibition of recombinant G9a catalytic SET domain (913 to 1193 residues) (unknown origin) expressed in Escherichia coli BL21 (DE3) codon plus RIL as...				J Med Chem 60: 1876-1891 (2017) Article DOI: 10.1021/acs.jmedchem.6b01645 BindingDB Entry DOI: 10.7270/Q2ZP4947
					More data for this Ligand-Target Pair
Histone-lysine N-methyltransferase EHMT1 (Homo sapiens (Human))	BDBM50501532 (CHEMBL4067656) Show SMILES COc1cc2nc(nc(NC3CCN(C)CC3)c2cc1OC)C1CCCCC1 Show InChI InChI=1S/C22H32N4O2/c1-26-11-9-16(10-12-26)23-22-17-13-19(27-2)20(28-3)14-18(17)24-21(25-22)15-7-5-4-6-8-15/h13-16H,4-12H2,1-3H3,(H,23,24,25)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	34	n/a	n/a	n/a	n/a	n/a	n/a
Icahn School of Medicine at Mount Sinai Curated by ChEMBL					Assay Description Inhibition of recombinant GLP catalytic SET domain (982 to 1266 residues) (unknown origin) expressed in Escherichia coli BL21 (DE3) codon plus RIL as...				J Med Chem 60: 1876-1891 (2017) Article DOI: 10.1021/acs.jmedchem.6b01645 BindingDB Entry DOI: 10.7270/Q2ZP4947
					More data for this Ligand-Target Pair
Histone-lysine N-methyltransferase EHMT1 (Homo sapiens (Human))	BDBM50501527 (CHEMBL4094167) Show SMILES CCCCN(C)c1nc(NC2CCN(C)CC2)c2cc(OC)c(OC)cc2n1 Show InChI InChI=1S/C21H33N5O2/c1-6-7-10-26(3)21-23-17-14-19(28-5)18(27-4)13-16(17)20(24-21)22-15-8-11-25(2)12-9-15/h13-15H,6-12H2,1-5H3,(H,22,23,24)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	35	n/a	n/a	n/a	n/a	n/a	n/a
Icahn School of Medicine at Mount Sinai Curated by ChEMBL					Assay Description Inhibition of recombinant GLP catalytic SET domain (982 to 1266 residues) (unknown origin) expressed in Escherichia coli BL21 (DE3) codon plus RIL as...				J Med Chem 60: 1876-1891 (2017) Article DOI: 10.1021/acs.jmedchem.6b01645 BindingDB Entry DOI: 10.7270/Q2ZP4947
					More data for this Ligand-Target Pair
Histone-lysine N-methyltransferase EHMT1 (Homo sapiens (Human))	BDBM50501530 (CHEMBL4078544) Show SMILES CCCCNc1nc(NC2CCN(C)CC2)c2cc(OC)c(OC)cc2n1 Show InChI InChI=1S/C20H31N5O2/c1-5-6-9-21-20-23-16-13-18(27-4)17(26-3)12-15(16)19(24-20)22-14-7-10-25(2)11-8-14/h12-14H,5-11H2,1-4H3,(H2,21,22,23,24)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	35	n/a	n/a	n/a	n/a	n/a	n/a
Icahn School of Medicine at Mount Sinai Curated by ChEMBL					Assay Description Inhibition of recombinant GLP catalytic SET domain (982 to 1266 residues) (unknown origin) expressed in Escherichia coli BL21 (DE3) codon plus RIL as...				J Med Chem 60: 1876-1891 (2017) Article DOI: 10.1021/acs.jmedchem.6b01645 BindingDB Entry DOI: 10.7270/Q2ZP4947
					More data for this Ligand-Target Pair
Histone-lysine N-methyltransferase EHMT1 (Homo sapiens (Human))	BDBM50268903 (CHEMBL4101782) Show SMILES CCCCN(CCC)c1nc(NC2CCN(C)CC2)c2cc(OC)c(OC)cc2n1 Show InChI InChI=1S/C23H37N5O2/c1-6-8-12-28(11-7-2)23-25-19-16-21(30-5)20(29-4)15-18(19)22(26-23)24-17-9-13-27(3)14-10-17/h15-17H,6-14H2,1-5H3,(H,24,25,26)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	36	n/a	n/a	n/a	n/a	n/a	n/a
Icahn School of Medicine at Mount Sinai Curated by ChEMBL					Assay Description Inhibition of human GLP catalytic domain (951 to 1235 residues) expressed in Escherichia coli BL21 (DE3) using biotinylated H3 (1 to 25 residues) as ...				Bioorg Med Chem 25: 4414-4423 (2017) Article DOI: 10.1016/j.bmc.2017.06.021 BindingDB Entry DOI: 10.7270/Q2X350ZG
					More data for this Ligand-Target Pair
Histone-lysine N-methyltransferase EHMT1 (Homo sapiens (Human))	BDBM50268900 (CHEMBL4092251) Show SMILES COc1cc2nc(nc(NC3CCN(C)CC3)c2cc1OC)N(C)c1ccccc1 Show InChI InChI=1S/C23H29N5O2/c1-27-12-10-16(11-13-27)24-22-18-14-20(29-3)21(30-4)15-19(18)25-23(26-22)28(2)17-8-6-5-7-9-17/h5-9,14-16H,10-13H2,1-4H3,(H,24,25,26)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	43	n/a	n/a	n/a	n/a	n/a	n/a
Icahn School of Medicine at Mount Sinai Curated by ChEMBL					Assay Description Inhibition of human GLP catalytic domain (951 to 1235 residues) expressed in Escherichia coli BL21 (DE3) using biotinylated H3 (1 to 25 residues) as ...				Bioorg Med Chem 25: 4414-4423 (2017) Article DOI: 10.1016/j.bmc.2017.06.021 BindingDB Entry DOI: 10.7270/Q2X350ZG
					More data for this Ligand-Target Pair
Histone-lysine N-methyltransferase EHMT1 (Homo sapiens (Human))	BDBM50501528 (CHEMBL4066625) Show SMILES CCCCCCCNc1nc(NC2CCN(C)CC2)c2cc(OC)c(OC)cc2n1 Show InChI InChI=1S/C23H37N5O2/c1-5-6-7-8-9-12-24-23-26-19-16-21(30-4)20(29-3)15-18(19)22(27-23)25-17-10-13-28(2)14-11-17/h15-17H,5-14H2,1-4H3,(H2,24,25,26,27)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	44	n/a	n/a	n/a	n/a	n/a	n/a
Icahn School of Medicine at Mount Sinai Curated by ChEMBL					Assay Description Inhibition of recombinant GLP catalytic SET domain (982 to 1266 residues) (unknown origin) expressed in Escherichia coli BL21 (DE3) codon plus RIL as...				J Med Chem 60: 1876-1891 (2017) Article DOI: 10.1021/acs.jmedchem.6b01645 BindingDB Entry DOI: 10.7270/Q2ZP4947
					More data for this Ligand-Target Pair
Histone-lysine N-methyltransferase EHMT1 (Homo sapiens (Human))	BDBM50268866 (CHEMBL4090654) Show SMILES COc1cc2nc(nc(NC3CCN(C)CC3)c2cc1OC)N(C)Cc1ccccc1 Show InChI InChI=1S/C24H31N5O2/c1-28-12-10-18(11-13-28)25-23-19-14-21(30-3)22(31-4)15-20(19)26-24(27-23)29(2)16-17-8-6-5-7-9-17/h5-9,14-15,18H,10-13,16H2,1-4H3,(H,25,26,27)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	46	n/a	n/a	n/a	n/a	n/a	n/a
Icahn School of Medicine at Mount Sinai Curated by ChEMBL					Assay Description Inhibition of human GLP catalytic domain (951 to 1235 residues) expressed in Escherichia coli BL21 (DE3) using biotinylated H3 (1 to 25 residues) as ...				Bioorg Med Chem 25: 4414-4423 (2017) Article DOI: 10.1016/j.bmc.2017.06.021 BindingDB Entry DOI: 10.7270/Q2X350ZG
					More data for this Ligand-Target Pair
Histone-lysine N-methyltransferase EHMT1 (Homo sapiens (Human))	BDBM50268901 (CHEMBL4095652) Show SMILES COc1cc2nc(nc(NC3CCN(C)CC3)c2cc1OC)N(C)CC(C)(C)C Show InChI InChI=1S/C22H35N5O2/c1-22(2,3)14-27(5)21-24-17-13-19(29-7)18(28-6)12-16(17)20(25-21)23-15-8-10-26(4)11-9-15/h12-13,15H,8-11,14H2,1-7H3,(H,23,24,25)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	50	n/a	n/a	n/a	n/a	n/a	n/a
Icahn School of Medicine at Mount Sinai Curated by ChEMBL					Assay Description Inhibition of human GLP catalytic domain (951 to 1235 residues) expressed in Escherichia coli BL21 (DE3) using biotinylated H3 (1 to 25 residues) as ...				Bioorg Med Chem 25: 4414-4423 (2017) Article DOI: 10.1016/j.bmc.2017.06.021 BindingDB Entry DOI: 10.7270/Q2X350ZG
					More data for this Ligand-Target Pair
Histone-lysine N-methyltransferase EHMT1 (Homo sapiens (Human))	BDBM50268868 (CHEMBL4082847) Show SMILES COCCN(C)c1nc(NC2CCN(C)CC2)c2cc(OC)c(OC)cc2n1 Show InChI InChI=1S/C20H31N5O3/c1-24-8-6-14(7-9-24)21-19-15-12-17(27-4)18(28-5)13-16(15)22-20(23-19)25(2)10-11-26-3/h12-14H,6-11H2,1-5H3,(H,21,22,23)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	58	n/a	n/a	n/a	n/a	n/a	n/a
Icahn School of Medicine at Mount Sinai Curated by ChEMBL					Assay Description Inhibition of human GLP catalytic domain (951 to 1235 residues) expressed in Escherichia coli BL21 (DE3) using biotinylated H3 (1 to 25 residues) as ...				Bioorg Med Chem 25: 4414-4423 (2017) Article DOI: 10.1016/j.bmc.2017.06.021 BindingDB Entry DOI: 10.7270/Q2X350ZG
					More data for this Ligand-Target Pair
Histone-lysine N-methyltransferase EHMT1 (Homo sapiens (Human))	BDBM50268895 (CHEMBL4080189) Show SMILES COc1cc2nc(NCCCCCCO)nc(NC3CCN(C)CC3)c2cc1OC Show InChI InChI=1S/C22H35N5O3/c1-27-11-8-16(9-12-27)24-21-17-14-19(29-2)20(30-3)15-18(17)25-22(26-21)23-10-6-4-5-7-13-28/h14-16,28H,4-13H2,1-3H3,(H2,23,24,25,26)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	59	n/a	n/a	n/a	n/a	n/a	n/a
Icahn School of Medicine at Mount Sinai Curated by ChEMBL					Assay Description Inhibition of human GLP catalytic domain (951 to 1235 residues) expressed in Escherichia coli BL21 (DE3) using biotinylated H3 (1 to 25 residues) as ...				Bioorg Med Chem 25: 4414-4423 (2017) Article DOI: 10.1016/j.bmc.2017.06.021 BindingDB Entry DOI: 10.7270/Q2X350ZG
					More data for this Ligand-Target Pair
Histone-lysine N-methyltransferase EHMT1 (Homo sapiens (Human))	BDBM50501529 (CHEMBL4104299) Show SMILES CCCCCNc1nc(NC2CCN(C)CC2)c2cc(OC)c(OC)cc2n1 Show InChI InChI=1S/C21H33N5O2/c1-5-6-7-10-22-21-24-17-14-19(28-4)18(27-3)13-16(17)20(25-21)23-15-8-11-26(2)12-9-15/h13-15H,5-12H2,1-4H3,(H2,22,23,24,25)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	63	n/a	n/a	n/a	n/a	n/a	n/a
Icahn School of Medicine at Mount Sinai Curated by ChEMBL					Assay Description Inhibition of recombinant GLP catalytic SET domain (982 to 1266 residues) (unknown origin) expressed in Escherichia coli BL21 (DE3) codon plus RIL as...				J Med Chem 60: 1876-1891 (2017) Article DOI: 10.1021/acs.jmedchem.6b01645 BindingDB Entry DOI: 10.7270/Q2ZP4947
					More data for this Ligand-Target Pair
Spindlin-1 (Homo sapiens)	BDBM50446376 (CHEMBL3109630) Show SMILES COc1cc2c(cc1OCCCN1CCCC1)N=C(N)C21CCC1 |t:19| Show InChI InChI=1S/C19H27N3O2/c1-23-16-12-14-15(21-18(20)19(14)6-4-7-19)13-17(16)24-11-5-10-22-8-2-3-9-22/h12-13H,2-11H2,1H3,(H2,20,21)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid PDB UniChem Similars	PDB Article PubMed	n/a	n/a	72	n/a	n/a	n/a	n/a	n/a	n/a
Icahn School of Medicine at Mount Sinai Curated by ChEMBL					Assay Description Inhibition of biotin-H3(1-23)K4me3 binding to recombinant human C-terminal His6-tagged SPIN1 (49 to 262 residues) expressed in Escherichia coli BL21 ...				J Med Chem 62: 8996-9007 (2019) Article DOI: 10.1021/acs.jmedchem.9b00522 BindingDB Entry DOI: 10.7270/Q2JM2F0X
					More data for this Ligand-Target Pair				3D Structure (crystal)
Histone-lysine N-methyltransferase EHMT1 (Homo sapiens (Human))	BDBM50268870 (CHEMBL4072358) Show SMILES COc1cc2nc(nc(NC3CCN(C)CC3)c2cc1OC)N(C)CCCO Show InChI InChI=1S/C20H31N5O3/c1-24-9-6-14(7-10-24)21-19-15-12-17(27-3)18(28-4)13-16(15)22-20(23-19)25(2)8-5-11-26/h12-14,26H,5-11H2,1-4H3,(H,21,22,23)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	73	n/a	n/a	n/a	n/a	n/a	n/a
Icahn School of Medicine at Mount Sinai Curated by ChEMBL					Assay Description Inhibition of human GLP catalytic domain (951 to 1235 residues) expressed in Escherichia coli BL21 (DE3) using biotinylated H3 (1 to 25 residues) as ...				Bioorg Med Chem 25: 4414-4423 (2017) Article DOI: 10.1016/j.bmc.2017.06.021 BindingDB Entry DOI: 10.7270/Q2X350ZG
					More data for this Ligand-Target Pair
Histone-lysine N-methyltransferase EHMT1 (Homo sapiens (Human))	BDBM50268902 (CHEMBL4083783) Show SMILES COc1cc2nc(NC3CCCCC3)nc(NC3CCN(C)CC3)c2cc1OC Show InChI InChI=1S/C22H33N5O2/c1-27-11-9-16(10-12-27)23-21-17-13-19(28-2)20(29-3)14-18(17)25-22(26-21)24-15-7-5-4-6-8-15/h13-16H,4-12H2,1-3H3,(H2,23,24,25,26)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	77	n/a	n/a	n/a	n/a	n/a	n/a
Icahn School of Medicine at Mount Sinai Curated by ChEMBL					Assay Description Inhibition of human GLP catalytic domain (951 to 1235 residues) expressed in Escherichia coli BL21 (DE3) using biotinylated H3 (1 to 25 residues) as ...				Bioorg Med Chem 25: 4414-4423 (2017) Article DOI: 10.1016/j.bmc.2017.06.021 BindingDB Entry DOI: 10.7270/Q2X350ZG
					More data for this Ligand-Target Pair
Spindlin-1 (Homo sapiens)	BDBM50519514 (CHEMBL4552020) Show SMILES COc1c(CN)cc(CN)cc1OCCCN1Cc2ccccc2C1 Show InChI InChI=1S/C20H27N3O2/c1-24-20-18(12-22)9-15(11-21)10-19(20)25-8-4-7-23-13-16-5-2-3-6-17(16)14-23/h2-3,5-6,9-10H,4,7-8,11-14,21-22H2,1H3	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	Purchase MCE PC cid PC sid PDB UniChem	PDB Article PubMed	n/a	n/a	77	n/a	n/a	n/a	n/a	n/a	n/a
Icahn School of Medicine at Mount Sinai Curated by ChEMBL					Assay Description Inhibition of biotin-H3(1-23)K4me3 binding to recombinant human C-terminal His6-tagged SPIN1 (49 to 262 residues) expressed in Escherichia coli BL21 ...				J Med Chem 62: 8996-9007 (2019) Article DOI: 10.1021/acs.jmedchem.9b00522 BindingDB Entry DOI: 10.7270/Q2JM2F0X
					More data for this Ligand-Target Pair				3D Structure (crystal)

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