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Compile Data Set for Download or QSAR

Found 16 hits with Last Name = 'banères' and Initial = 'jl'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Glutathione S-transferase kappa 1


(Homo sapiens (Human))
BDBM50422268
PNG
(GLUTATHIONE | GSH)
Show SMILES N[C@@H](CCC(=O)N[C@@H](CS)C(=O)NCC(O)=O)C(O)=O |r|
Show InChI InChI=1S/C10H17N3O6S/c11-5(10(18)19)1-2-7(14)13-6(4-20)9(17)12-3-8(15)16/h5-6,20H,1-4,11H2,(H,12,17)(H,13,14)(H,15,16)(H,18,19)/t5-,6-/m0/s1
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Article
PubMed
n/an/a 20n/an/an/an/an/an/a



Université Sidi Mohamed Ben Abdellah

Curated by ChEMBL


Assay Description
Affinity towards recombinant Glutathione S-transferase (GST) Enzyme.


J Med Chem 41: 2278-88 (1998)


Article DOI: 10.1021/jm970518m
BindingDB Entry DOI: 10.7270/Q2154G56
More data for this
Ligand-Target Pair
Leukotriene B4 receptor 1


(Homo sapiens (Human))
BDBM50087679
PNG
(2-[1-Hydroxy-3-((E)-3-hydroxy-7-phenyl-hept-1-enyl...)
Show SMILES CN(C)C(=O)CC1(O)CCCC(C1)\C=C\C(O)CCCCc1ccccc1
Show InChI InChI=1S/C23H35NO3/c1-24(2)22(26)18-23(27)16-8-12-20(17-23)14-15-21(25)13-7-6-11-19-9-4-3-5-10-19/h3-5,9-10,14-15,20-21,25,27H,6-8,11-13,16-18H2,1-2H3/b15-14+
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n/an/a 40n/an/an/an/an/an/a



UPRESA-CNRS 5074

Curated by ChEMBL


Assay Description
Compound was tested for inhibition against binding of radioligand [3H]-LTB4 to Leukotriene B4 receptor in human neutrophil membranes


Bioorg Med Chem Lett 10: 811-4 (2000)


BindingDB Entry DOI: 10.7270/Q2W37VHF
More data for this
Ligand-Target Pair
Leukotriene B4 receptor 1


(Homo sapiens (Human))
BDBM50087682
PNG
(CHEMBL354872 | Sodium; [1-hydroxy-3-((E)-3-hydroxy...)
Show SMILES OC(CCCCc1ccccc1)\C=C\C1CCCC(O)(CC(O)=O)C1
Show InChI InChI=1S/C21H30O4/c22-19(11-5-4-9-17-7-2-1-3-8-17)13-12-18-10-6-14-21(25,15-18)16-20(23)24/h1-3,7-8,12-13,18-19,22,25H,4-6,9-11,14-16H2,(H,23,24)/b13-12+
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n/an/a 300n/an/an/an/an/an/a



UPRESA-CNRS 5074

Curated by ChEMBL


Assay Description
Compound was tested for inhibition against binding of radioligand [3H]-LTB4 to Leukotriene B4 receptor in human neutrophil membranes


Bioorg Med Chem Lett 10: 811-4 (2000)


BindingDB Entry DOI: 10.7270/Q2W37VHF
More data for this
Ligand-Target Pair
Leukotriene B4 receptor 1


(Homo sapiens (Human))
BDBM50087680
PNG
(2-{3-[(E)-7-(4-Azido-phenyl)-3-hydroxy-hept-1-enyl...)
Show SMILES CN(C)C(=O)CC1(O)CCCC(C1)\C=C\C(O)CCCCc1ccc(cc1)N=[N+]=[N-]
Show InChI InChI=1S/C23H34N4O3/c1-27(2)22(29)17-23(30)15-5-7-19(16-23)11-14-21(28)8-4-3-6-18-9-12-20(13-10-18)25-26-24/h9-14,19,21,28,30H,3-8,15-17H2,1-2H3/b14-11+
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n/an/a 2.00E+3n/an/an/an/an/an/a



UPRESA-CNRS 5074

Curated by ChEMBL


Assay Description
Compound was tested for inhibition against binding of radioligand [3H]-LTB4 to Leukotriene B4 receptor in human neutrophil membranes


Bioorg Med Chem Lett 10: 811-4 (2000)


BindingDB Entry DOI: 10.7270/Q2W37VHF
More data for this
Ligand-Target Pair
Leukotriene B4 receptor 1


(Homo sapiens (Human))
BDBM50087681
PNG
(CHEMBL164721 | Sodium; {3-[(E)-7-(4-azido-phenyl)-...)
Show SMILES OC(CCCCc1ccc(cc1)N=[N+]=[N-])\C=C\C1CCCC(O)(CC(O)=O)C1
Show InChI InChI=1S/C21H29N3O4/c22-24-23-18-10-7-16(8-11-18)4-1-2-6-19(25)12-9-17-5-3-13-21(28,14-17)15-20(26)27/h7-12,17,19,25,28H,1-6,13-15H2,(H,26,27)/b12-9+
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n/an/a 2.00E+3n/an/an/an/an/an/a



UPRESA-CNRS 5074

Curated by ChEMBL


Assay Description
Compound was tested for inhibition against binding of radioligand [3H]-LTB4 to Leukotriene B4 receptor in human neutrophil membranes


Bioorg Med Chem Lett 10: 811-4 (2000)


BindingDB Entry DOI: 10.7270/Q2W37VHF
More data for this
Ligand-Target Pair
Leukotriene B4 receptor 1


(Homo sapiens (Human))
BDBM50087680
PNG
(2-{3-[(E)-7-(4-Azido-phenyl)-3-hydroxy-hept-1-enyl...)
Show SMILES CN(C)C(=O)CC1(O)CCCC(C1)\C=C\C(O)CCCCc1ccc(cc1)N=[N+]=[N-]
Show InChI InChI=1S/C23H34N4O3/c1-27(2)22(29)17-23(30)15-5-7-19(16-23)11-14-21(28)8-4-3-6-18-9-12-20(13-10-18)25-26-24/h9-14,19,21,28,30H,3-8,15-17H2,1-2H3/b14-11+
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n/an/a 2.00E+3n/an/an/an/an/an/a



UPRESA-CNRS 5074

Curated by ChEMBL


Assay Description
Compound was tested for inhibition against binding of radioligand [3H]-LTB4 to Leukotriene B4 receptor in human neutrophil membranes


Bioorg Med Chem Lett 10: 811-4 (2000)


BindingDB Entry DOI: 10.7270/Q2W37VHF
More data for this
Ligand-Target Pair
Integrin alpha-5/beta-1


(Homo sapiens (Human))
BDBM50241180
PNG
((6S,12S,15S)-1,6-diamino-12-(carboxymethyl)-16-hyd...)
Show SMILES [#7]-[#6@@H](-[#6]-[#6]-[#6]\[#7]=[#6](/[#7])-[#7])-[#6](=O)-[#7]-[#6]-[#6](=O)-[#7]-[#6@@H](-[#6]-[#6](-[#8])=O)-[#6](=O)-[#7]-[#6@@H](-[#6]-[#8])-[#6](-[#8])=O |r|
Show InChI InChI=1S/C15H27N7O8/c16-7(2-1-3-19-15(17)18)12(27)20-5-10(24)21-8(4-11(25)26)13(28)22-9(6-23)14(29)30/h7-9,23H,1-6,16H2,(H,20,27)(H,21,24)(H,22,28)(H,25,26)(H,29,30)(H4,17,18,19)/t7-,8-,9-/m0/s1
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n/an/a 2.20E+3n/an/an/an/an/an/a



Université Montpellier I

Curated by ChEMBL


Assay Description
Inhibition of fibronectin (GST-3Fn8-11) binding to recombinant soluble mini integrin alpha5-beta1


Bioorg Med Chem Lett 13: 1561-4 (2003)


BindingDB Entry DOI: 10.7270/Q2BR8RK2
More data for this
Ligand-Target Pair
Glutathione S-transferase kappa 1


(Homo sapiens (Human))
BDBM50064878
PNG
(5-Mercaptomethyl-undecanedioic acid | CHEMBL75497)
Show SMILES OC(=O)CCCCCC(CS)CCCC(O)=O
Show InChI InChI=1S/C12H22O4S/c13-11(14)7-3-1-2-5-10(9-17)6-4-8-12(15)16/h10,17H,1-9H2,(H,13,14)(H,15,16)
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n/an/a 5.20E+3n/an/an/an/an/an/a



Université Sidi Mohamed Ben Abdellah

Curated by ChEMBL


Assay Description
Affinity towards recombinant Glutathione S-transferase (GST) Enzyme.


J Med Chem 41: 2278-88 (1998)


Article DOI: 10.1021/jm970518m
BindingDB Entry DOI: 10.7270/Q2154G56
More data for this
Ligand-Target Pair
Leukotriene B4 receptor 1


(Homo sapiens (Human))
BDBM50087677
PNG
(2-{3-[(E)-7-(4-Azido-3-iodo-phenyl)-3-hydroxy-hept...)
Show SMILES CN(C)C(=O)CC1(O)CCCC(C1)\C=C\C(O)CCCCc1ccc(N=[N+]=[N-])c(I)c1
Show InChI InChI=1S/C23H33IN4O3/c1-28(2)22(30)16-23(31)13-5-7-18(15-23)9-11-19(29)8-4-3-6-17-10-12-21(26-27-25)20(24)14-17/h9-12,14,18-19,29,31H,3-8,13,15-16H2,1-2H3/b11-9+
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n/an/a 6.00E+3n/an/an/an/an/an/a



UPRESA-CNRS 5074

Curated by ChEMBL


Assay Description
Compound was tested for inhibition against binding of radioligand [3H]-LTB4 to Leukotriene B4 receptor in human neutrophil membranes


Bioorg Med Chem Lett 10: 811-4 (2000)


BindingDB Entry DOI: 10.7270/Q2W37VHF
More data for this
Ligand-Target Pair
Leukotriene B4 receptor 1


(Homo sapiens (Human))
BDBM50087678
PNG
(CHEMBL168507 | Sodium; {3-[(E)-7-(4-azido-3-iodo-p...)
Show SMILES OC(CCCCc1ccc(N=[N+]=[N-])c(I)c1)\C=C\C1CCCC(O)(CC(O)=O)C1
Show InChI InChI=1S/C21H28IN3O4/c22-18-12-15(8-10-19(18)24-25-23)4-1-2-6-17(26)9-7-16-5-3-11-21(29,13-16)14-20(27)28/h7-10,12,16-17,26,29H,1-6,11,13-14H2,(H,27,28)/b9-7+
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n/an/a>1.00E+4n/an/an/an/an/an/a



UPRESA-CNRS 5074

Curated by ChEMBL


Assay Description
Compound was tested for inhibition against binding of radioligand [3H]-LTB4 to Leukotriene B4 receptor in human neutrophil membranes


Bioorg Med Chem Lett 10: 811-4 (2000)


BindingDB Entry DOI: 10.7270/Q2W37VHF
More data for this
Ligand-Target Pair
Leukotriene B4 receptor 1


(Homo sapiens (Human))
BDBM50087677
PNG
(2-{3-[(E)-7-(4-Azido-3-iodo-phenyl)-3-hydroxy-hept...)
Show SMILES CN(C)C(=O)CC1(O)CCCC(C1)\C=C\C(O)CCCCc1ccc(N=[N+]=[N-])c(I)c1
Show InChI InChI=1S/C23H33IN4O3/c1-28(2)22(30)16-23(31)13-5-7-18(15-23)9-11-19(29)8-4-3-6-17-10-12-21(26-27-25)20(24)14-17/h9-12,14,18-19,29,31H,3-8,13,15-16H2,1-2H3/b11-9+
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n/an/a>1.00E+4n/an/an/an/an/an/a



UPRESA-CNRS 5074

Curated by ChEMBL


Assay Description
Compound was tested for inhibition against binding of radioligand [3H]-LTB4 to Leukotriene B4 receptor in human neutrophil membranes


Bioorg Med Chem Lett 10: 811-4 (2000)


BindingDB Entry DOI: 10.7270/Q2W37VHF
More data for this
Ligand-Target Pair
Glutathione S-transferase kappa 1


(Homo sapiens (Human))
BDBM50064879
PNG
(5-Mercaptomethyl-decanedioic acid | CHEMBL73552)
Show SMILES OC(=O)CCCCC(CS)CCCC(O)=O
Show InChI InChI=1S/C11H20O4S/c12-10(13)6-2-1-4-9(8-16)5-3-7-11(14)15/h9,16H,1-8H2,(H,12,13)(H,14,15)
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n/an/a 1.01E+4n/an/an/an/an/an/a



Université Sidi Mohamed Ben Abdellah

Curated by ChEMBL


Assay Description
Affinity towards recombinant Glutathione S-transferase (GST) Enzyme.


J Med Chem 41: 2278-88 (1998)


Article DOI: 10.1021/jm970518m
BindingDB Entry DOI: 10.7270/Q2154G56
More data for this
Ligand-Target Pair
Integrin alpha-5/beta-1


(Homo sapiens (Human))
BDBM50127296
PNG
((R)-3-[(S)-5-(3-Guanidino-propylcarbamoyl)-2-oxo-1...)
Show SMILES NC(=N)NCCCNC(=O)[C@H]1CCC(=O)N2C[C@H](CCC(O)=O)[C@H]2C1
Show InChI InChI=1S/C16H27N5O4/c17-16(18)20-7-1-6-19-15(25)10-2-4-13(22)21-9-11(12(21)8-10)3-5-14(23)24/h10-12H,1-9H2,(H,19,25)(H,23,24)(H4,17,18,20)/t10-,11-,12+/m0/s1
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n/an/a 6.50E+4n/an/an/an/an/an/a



Université Montpellier I

Curated by ChEMBL


Assay Description
Inhibition of fibronectin (GST-3Fn8-11) binding to recombinant soluble mini integrin alpha5-beta1


Bioorg Med Chem Lett 13: 1561-4 (2003)


BindingDB Entry DOI: 10.7270/Q2BR8RK2
More data for this
Ligand-Target Pair
Integrin alpha-5/beta-1


(Homo sapiens (Human))
BDBM50127297
PNG
(3-[5-(3-Guanidino-propylcarbamoyl)-2-oxo-1-aza-bic...)
Show SMILES NC(=N)NCCCNC(=O)C1CCC(=O)N2CC(CCC(O)=O)C2C1
Show InChI InChI=1S/C16H27N5O4/c17-16(18)20-7-1-6-19-15(25)10-2-4-13(22)21-9-11(12(21)8-10)3-5-14(23)24/h10-12H,1-9H2,(H,19,25)(H,23,24)(H4,17,18,20)
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n/an/a 1.30E+6n/an/an/an/an/an/a



Université Montpellier I

Curated by ChEMBL


Assay Description
Inhibition of fibronectin (GST-3Fn8-11) binding to recombinant soluble mini integrin alpha5-beta1


Bioorg Med Chem Lett 13: 1561-4 (2003)


BindingDB Entry DOI: 10.7270/Q2BR8RK2
More data for this
Ligand-Target Pair
Glutathione S-transferase kappa 1


(Homo sapiens (Human))
BDBM50064881
PNG
(4-Mercaptomethyl-decanedioic acid | CHEMBL76285)
Show SMILES OC(=O)CCCCCC(CS)CCC(O)=O
Show InChI InChI=1S/C11H20O4S/c12-10(13)5-3-1-2-4-9(8-16)6-7-11(14)15/h9,16H,1-8H2,(H,12,13)(H,14,15)
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n/an/a 1.80E+6n/an/an/an/an/an/a



Université Sidi Mohamed Ben Abdellah

Curated by ChEMBL


Assay Description
Affinity towards recombinant Glutathione S-transferase (GST) Enzyme.


J Med Chem 41: 2278-88 (1998)


Article DOI: 10.1021/jm970518m
BindingDB Entry DOI: 10.7270/Q2154G56
More data for this
Ligand-Target Pair
Integrin alpha-5/beta-1


(Homo sapiens (Human))
BDBM50127298
PNG
((R)-3-[(R)-5-(3-Guanidino-propylcarbamoyl)-2-oxo-1...)
Show SMILES NC(=N)NCCCNC(=O)[C@@H]1CCC(=O)N2C[C@H](CCC(O)=O)[C@H]2C1
Show InChI InChI=1S/C16H27N5O4/c17-16(18)20-7-1-6-19-15(25)10-2-4-13(22)21-9-11(12(21)8-10)3-5-14(23)24/h10-12H,1-9H2,(H,19,25)(H,23,24)(H4,17,18,20)/t10-,11+,12-/m1/s1
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n/an/a 3.10E+6n/an/an/an/an/an/a



Université Montpellier I

Curated by ChEMBL


Assay Description
Inhibition of fibronectin (GST-3Fn8-11) binding to recombinant soluble mini integrin alpha5-beta1


Bioorg Med Chem Lett 13: 1561-4 (2003)


BindingDB Entry DOI: 10.7270/Q2BR8RK2
More data for this
Ligand-Target Pair