BindingDB PrimarySearch

Found 77 hits with Last Name = 'barnes' and Initial = 't'
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Nociceptin receptor (Homo sapiens (Human))	BDBM50475328 (CHEMBL414782) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	0.00500	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Ferrara Curated by ChEMBL					Assay Description Receptor binding affinity for recombinant human N/OFQ peptide receptor (NOP) expressed in chinese hamster ovary cells				J Med Chem 48: 1421-7 (2005) Article DOI: 10.1021/jm040106v BindingDB Entry DOI: 10.7270/Q2J38WBW
University of Ferrara Curated by ChEMBL					More data for this Ligand-Target Pair
Nociceptin receptor (Homo sapiens (Human))	BDBM50475327 (CHEMBL410653) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	0.00700	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Ferrara Curated by ChEMBL					Assay Description Receptor binding affinity for recombinant human N/OFQ peptide receptor (NOP) expressed in chinese hamster ovary cells				J Med Chem 48: 1421-7 (2005) Article DOI: 10.1021/jm040106v BindingDB Entry DOI: 10.7270/Q2J38WBW
University of Ferrara Curated by ChEMBL					More data for this Ligand-Target Pair
Nociceptin receptor (Homo sapiens (Human))	BDBM50475330 (CHEMBL442297) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	0.0200	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Ferrara Curated by ChEMBL					Assay Description Receptor binding affinity for recombinant human N/OFQ peptide receptor (NOP) expressed in chinese hamster ovary cells				J Med Chem 48: 1421-7 (2005) Article DOI: 10.1021/jm040106v BindingDB Entry DOI: 10.7270/Q2J38WBW
University of Ferrara Curated by ChEMBL					More data for this Ligand-Target Pair
Nociceptin receptor (Homo sapiens (Human))	BDBM86660 (OFQ/N UFP-102) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	0.0210	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Section of Pharmacology Curated by PDSP K_i Database									J Pharmacol Exp Ther 312: 1114-23 (2005) Article DOI: 10.1124/jpet.104.077339 BindingDB Entry DOI: 10.7270/Q2222SC4
Section of Pharmacology Curated by PDSP K_i Database					More data for this Ligand-Target Pair
Nociceptin receptor (Homo sapiens (Human))	BDBM50475333 (CHEMBL264846) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	0.0220	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Ferrara Curated by ChEMBL					Assay Description Receptor binding affinity for recombinant human N/OFQ peptide receptor (NOP) expressed in chinese hamster ovary cells				J Med Chem 48: 1421-7 (2005) Article DOI: 10.1021/jm040106v BindingDB Entry DOI: 10.7270/Q2J38WBW
University of Ferrara Curated by ChEMBL					More data for this Ligand-Target Pair
Nociceptin receptor (Homo sapiens (Human))	BDBM50475331 (CHEMBL411649) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	0.0250	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Ferrara Curated by ChEMBL					Assay Description Receptor binding affinity for recombinant human N/OFQ peptide receptor (NOP) expressed in chinese hamster ovary cells				J Med Chem 48: 1421-7 (2005) Article DOI: 10.1021/jm040106v BindingDB Entry DOI: 10.7270/Q2J38WBW
University of Ferrara Curated by ChEMBL					More data for this Ligand-Target Pair
Nociceptin receptor (Homo sapiens (Human))	BDBM50475325 (CHEMBL262544) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	0.0320	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Ferrara Curated by ChEMBL					Assay Description Receptor binding affinity for recombinant human N/OFQ peptide receptor (NOP) expressed in chinese hamster ovary cells				J Med Chem 48: 1421-7 (2005) Article DOI: 10.1021/jm040106v BindingDB Entry DOI: 10.7270/Q2J38WBW
University of Ferrara Curated by ChEMBL					More data for this Ligand-Target Pair
Nociceptin receptor (Homo sapiens (Human))	BDBM50475329 (CHEMBL263588) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	0.0480	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Ferrara Curated by ChEMBL					Assay Description Receptor binding affinity for recombinant human N/OFQ peptide receptor (NOP) expressed in chinese hamster ovary cells				J Med Chem 48: 1421-7 (2005) Article DOI: 10.1021/jm040106v BindingDB Entry DOI: 10.7270/Q2J38WBW
University of Ferrara Curated by ChEMBL					More data for this Ligand-Target Pair
Nociceptin receptor (Homo sapiens (Human))	BDBM50004178 (Nociceptin \| Nociceptin/orphanin FQ \| ORPHANIN FQ) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase MCE KEGG PC cid PC sid UniChem Similars	Article PubMed	0.0490	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Ferrara Curated by ChEMBL					Assay Description Binding affinity for recombinant human N/OFQ peptide receptor (NOP) expressed in chinese hamster ovary cells				J Med Chem 48: 1421-7 (2005) Article DOI: 10.1021/jm040106v BindingDB Entry DOI: 10.7270/Q2J38WBW
University of Ferrara Curated by ChEMBL					More data for this Ligand-Target Pair
Nociceptin receptor (Homo sapiens (Human))	BDBM86660 (OFQ/N UFP-102) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	0.0680	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Section of Pharmacology Curated by PDSP K_i Database									J Pharmacol Exp Ther 312: 1114-23 (2005) Article DOI: 10.1124/jpet.104.077339 BindingDB Entry DOI: 10.7270/Q2222SC4
Section of Pharmacology Curated by PDSP K_i Database					More data for this Ligand-Target Pair
Nociceptin receptor (Homo sapiens (Human))	BDBM86660 (OFQ/N UFP-102) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	0.0760	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Section of Pharmacology Curated by PDSP K_i Database									J Pharmacol Exp Ther 312: 1114-23 (2005) Article DOI: 10.1124/jpet.104.077339 BindingDB Entry DOI: 10.7270/Q2222SC4
Section of Pharmacology Curated by PDSP K_i Database					More data for this Ligand-Target Pair
Nociceptin receptor (Homo sapiens (Human))	BDBM50472747 (CHEMBL414767) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	0.129	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Ferrara Curated by ChEMBL					Assay Description Receptor binding affinity for recombinant human N/OFQ peptide receptor (NOP) expressed in chinese hamster ovary cells				J Med Chem 48: 1421-7 (2005) Article DOI: 10.1021/jm040106v BindingDB Entry DOI: 10.7270/Q2J38WBW
University of Ferrara Curated by ChEMBL					More data for this Ligand-Target Pair
Nociceptin receptor (Homo sapiens (Human))	BDBM50475326 (CHEMBL410145) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	0.129	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Ferrara Curated by ChEMBL					Assay Description Receptor binding affinity for recombinant human N/OFQ peptide receptor (NOP) expressed in chinese hamster ovary cells				J Med Chem 48: 1421-7 (2005) Article DOI: 10.1021/jm040106v BindingDB Entry DOI: 10.7270/Q2J38WBW
University of Ferrara Curated by ChEMBL					More data for this Ligand-Target Pair
Nociceptin receptor (Homo sapiens (Human))	BDBM85822 (Demethyl-AMPA \| OFQ/N \| OFQ/N (1-11) \| OFQ/N (1-11...) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	0.140	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Section of Pharmacology Curated by PDSP K_i Database									J Pharmacol Exp Ther 312: 1114-23 (2005) Article DOI: 10.1124/jpet.104.077339 BindingDB Entry DOI: 10.7270/Q2222SC4
Section of Pharmacology Curated by PDSP K_i Database					More data for this Ligand-Target Pair
Nociceptin receptor (Homo sapiens (Human))	BDBM50475332 (CHEMBL413944) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	0.240	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Ferrara Curated by ChEMBL					Assay Description Receptor binding affinity for recombinant human N/OFQ peptide receptor (NOP) expressed in chinese hamster ovary cells				J Med Chem 48: 1421-7 (2005) Article DOI: 10.1021/jm040106v BindingDB Entry DOI: 10.7270/Q2J38WBW
University of Ferrara Curated by ChEMBL					More data for this Ligand-Target Pair
Nociceptin receptor (MOUSE)	BDBM86660 (OFQ/N UFP-102) Show SMILES Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	0.360	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Section of Pharmacology Curated by PDSP K_i Database									J Pharmacol Exp Ther 312: 1114-23 (2005) Article DOI: 10.1124/jpet.104.077339 BindingDB Entry DOI: 10.7270/Q2222SC4
Section of Pharmacology Curated by PDSP K_i Database					More data for this Ligand-Target Pair
Nociceptin receptor (MOUSE)	BDBM86660 (OFQ/N UFP-102) Show SMILES Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	0.380	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Section of Pharmacology Curated by PDSP K_i Database									J Pharmacol Exp Ther 312: 1114-23 (2005) Article DOI: 10.1124/jpet.104.077339 BindingDB Entry DOI: 10.7270/Q2222SC4
Section of Pharmacology Curated by PDSP K_i Database					More data for this Ligand-Target Pair
Nociceptin receptor (Homo sapiens (Human))	BDBM50472746 (CHEMBL411621) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	0.417	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Ferrara Curated by ChEMBL					Assay Description Receptor binding affinity for recombinant human N/OFQ peptide receptor (NOP) expressed in chinese hamster ovary cells				J Med Chem 48: 1421-7 (2005) Article DOI: 10.1021/jm040106v BindingDB Entry DOI: 10.7270/Q2J38WBW
University of Ferrara Curated by ChEMBL					More data for this Ligand-Target Pair
Nociceptin receptor (GUINEA PIG)	BDBM86660 (OFQ/N UFP-102) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	0.580	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Section of Pharmacology Curated by PDSP K_i Database									J Pharmacol Exp Ther 312: 1114-23 (2005) Article DOI: 10.1124/jpet.104.077339 BindingDB Entry DOI: 10.7270/Q2222SC4
Section of Pharmacology Curated by PDSP K_i Database					More data for this Ligand-Target Pair
Nociceptin receptor (MOUSE)	BDBM86660 (OFQ/N UFP-102) Show SMILES Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	0.650	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Section of Pharmacology Curated by PDSP K_i Database									J Pharmacol Exp Ther 312: 1114-23 (2005) Article DOI: 10.1124/jpet.104.077339 BindingDB Entry DOI: 10.7270/Q2222SC4
Section of Pharmacology Curated by PDSP K_i Database					More data for this Ligand-Target Pair
Nociceptin receptor (MOUSE)	BDBM85822 (Demethyl-AMPA \| OFQ/N \| OFQ/N (1-11) \| OFQ/N (1-11...) Show SMILES Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	1.20	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Section of Pharmacology Curated by PDSP K_i Database									J Pharmacol Exp Ther 312: 1114-23 (2005) Article DOI: 10.1124/jpet.104.077339 BindingDB Entry DOI: 10.7270/Q2222SC4
Section of Pharmacology Curated by PDSP K_i Database					More data for this Ligand-Target Pair
Nociceptin receptor (MOUSE)	BDBM85822 (Demethyl-AMPA \| OFQ/N \| OFQ/N (1-11) \| OFQ/N (1-11...) Show SMILES Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	2.29	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Section of Pharmacology Curated by PDSP K_i Database									J Pharmacol Exp Ther 312: 1114-23 (2005) Article DOI: 10.1124/jpet.104.077339 BindingDB Entry DOI: 10.7270/Q2222SC4
Section of Pharmacology Curated by PDSP K_i Database					More data for this Ligand-Target Pair
Nociceptin receptor (RAT)	BDBM86660 (OFQ/N UFP-102) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	2.69	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Section of Pharmacology Curated by PDSP K_i Database									J Pharmacol Exp Ther 312: 1114-23 (2005) Article DOI: 10.1124/jpet.104.077339 BindingDB Entry DOI: 10.7270/Q2222SC4
Section of Pharmacology Curated by PDSP K_i Database					More data for this Ligand-Target Pair
Kappa-type opioid receptor (Homo sapiens (Human))	BDBM86660 (OFQ/N UFP-102) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	4.79	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Section of Pharmacology Curated by PDSP K_i Database									J Pharmacol Exp Ther 312: 1114-23 (2005) Article DOI: 10.1124/jpet.104.077339 BindingDB Entry DOI: 10.7270/Q2222SC4
Section of Pharmacology Curated by PDSP K_i Database					More data for this Ligand-Target Pair
Nociceptin receptor (GUINEA PIG)	BDBM85822 (Demethyl-AMPA \| OFQ/N \| OFQ/N (1-11) \| OFQ/N (1-11...) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	11.5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Section of Pharmacology Curated by PDSP K_i Database									J Pharmacol Exp Ther 312: 1114-23 (2005) Article DOI: 10.1124/jpet.104.077339 BindingDB Entry DOI: 10.7270/Q2222SC4
Section of Pharmacology Curated by PDSP K_i Database					More data for this Ligand-Target Pair
Nociceptin receptor (MOUSE)	BDBM85822 (Demethyl-AMPA \| OFQ/N \| OFQ/N (1-11) \| OFQ/N (1-11...) Show SMILES Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	17.4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Section of Pharmacology Curated by PDSP K_i Database									J Pharmacol Exp Ther 312: 1114-23 (2005) Article DOI: 10.1124/jpet.104.077339 BindingDB Entry DOI: 10.7270/Q2222SC4
Section of Pharmacology Curated by PDSP K_i Database					More data for this Ligand-Target Pair
Nociceptin receptor (RAT)	BDBM85822 (Demethyl-AMPA \| OFQ/N \| OFQ/N (1-11) \| OFQ/N (1-11...) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	57.5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Section of Pharmacology Curated by PDSP K_i Database									J Pharmacol Exp Ther 312: 1114-23 (2005) Article DOI: 10.1124/jpet.104.077339 BindingDB Entry DOI: 10.7270/Q2222SC4
Section of Pharmacology Curated by PDSP K_i Database					More data for this Ligand-Target Pair
Mu-type opioid receptor (Homo sapiens (Human))	BDBM86660 (OFQ/N UFP-102) Show SMILES Show InChI	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	70.8	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Section of Pharmacology Curated by PDSP K_i Database									J Pharmacol Exp Ther 312: 1114-23 (2005) Article DOI: 10.1124/jpet.104.077339 BindingDB Entry DOI: 10.7270/Q2222SC4
Section of Pharmacology Curated by PDSP K_i Database					More data for this Ligand-Target Pair
Delta-type opioid receptor (Homo sapiens (Human))	BDBM86660 (OFQ/N UFP-102) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	380	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Section of Pharmacology Curated by PDSP K_i Database									J Pharmacol Exp Ther 312: 1114-23 (2005) Article DOI: 10.1124/jpet.104.077339 BindingDB Entry DOI: 10.7270/Q2222SC4
Section of Pharmacology Curated by PDSP K_i Database					More data for this Ligand-Target Pair
Heat shock protein HSP 90-beta (Homo sapiens (Human))	BDBM227589 (Radicicol) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid PDB UniChem	PDB Article PubMed	n/a	n/a	19	n/a	n/a	n/a	n/a	n/a	n/a
University of California Curated by ChEMBL					Assay Description Inhibition of HSP90 (unknown origin)				J Nat Prod 77: 618-24 (2014) Article DOI: 10.1021/np400889x BindingDB Entry DOI: 10.7270/Q2ZS30H3
University of California Curated by ChEMBL					More data for this Ligand-Target Pair				3D Structure (crystal)
Reverse transcriptase/RNaseH (Human immunodeficiency virus 1)	BDBM33410 (CHEMBL16755 \| N-hydroxyisoquinolinedione, 2) Show SMILES ON1C(=O)Cc2ccccc2C1=O Show InChI	PDB MMDB UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	Purchase CHEMBL MCE MMDB PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	135	n/a	n/a	n/a	n/a	8.0	20
Gilead Sciences Inc.					Assay Description Enzyme activity was measuring substrate hydrolysis of RNase H. The intact substrate has a low background fluorescent signal and provides up to 50-fol...				J Med Chem 52: 5781-4 (2009) Article DOI: 10.1021/jm900597q BindingDB Entry DOI: 10.7270/Q2TM78F2
Gilead Sciences Inc.					More data for this Ligand-Target Pair
Reverse transcriptase/RNaseH (Human immunodeficiency virus 1)	BDBM33419 (pyrimidinol carboxylic acid, 11) Show SMILES Show InChI	PDB MMDB UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	175	n/a	n/a	n/a	n/a	8.0	20
Gilead Sciences Inc.					Assay Description Enzyme activity was measuring substrate hydrolysis of RNase H. The intact substrate has a low background fluorescent signal and provides up to 50-fol...				J Med Chem 52: 5781-4 (2009) Article DOI: 10.1021/jm900597q BindingDB Entry DOI: 10.7270/Q2TM78F2
Gilead Sciences Inc.					More data for this Ligand-Target Pair
Reverse transcriptase/RNaseH (Human immunodeficiency virus 1)	BDBM33411 (β-Thujaplicinol \| hydroxytropolone, 3) Show SMILES CC(C)c1ccc(O)c(=O)c(O)c1 Show InChI	PDB MMDB UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	MMDB PC cid PC sid PDB UniChem Patents Similars	MMDB PDB Article PubMed	n/a	n/a	660	n/a	n/a	n/a	n/a	8.0	20
Gilead Sciences Inc.					Assay Description Enzyme activity was measuring substrate hydrolysis of RNase H. The intact substrate has a low background fluorescent signal and provides up to 50-fol...				J Med Chem 52: 5781-4 (2009) Article DOI: 10.1021/jm900597q BindingDB Entry DOI: 10.7270/Q2TM78F2
Gilead Sciences Inc.					More data for this Ligand-Target Pair				3D Structure (crystal)
Reverse transcriptase/RNaseH (Human immunodeficiency virus 1)	BDBM33418 (pyrimidinol carboxylic acid, 10) Show SMILES Show InChI	PDB MMDB UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	MMDB PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.15E+3	n/a	n/a	n/a	n/a	8.0	20
Gilead Sciences Inc.					Assay Description Enzyme activity was measuring substrate hydrolysis of RNase H. The intact substrate has a low background fluorescent signal and provides up to 50-fol...				J Med Chem 52: 5781-4 (2009) Article DOI: 10.1021/jm900597q BindingDB Entry DOI: 10.7270/Q2TM78F2
Gilead Sciences Inc.					More data for this Ligand-Target Pair
Reverse transcriptase/RNaseH (Human immunodeficiency virus 1)	BDBM33417 (pyrimidinol carboxylic acid, 9) Show SMILES Show InChI	PDB MMDB UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	MMDB PC cid PC sid PDB UniChem Similars	PDB Article PubMed	n/a	n/a	1.45E+3	n/a	n/a	n/a	n/a	8.0	20
Gilead Sciences Inc.					Assay Description Enzyme activity was measuring substrate hydrolysis of RNase H. The intact substrate has a low background fluorescent signal and provides up to 50-fol...				J Med Chem 52: 5781-4 (2009) Article DOI: 10.1021/jm900597q BindingDB Entry DOI: 10.7270/Q2TM78F2
Gilead Sciences Inc.					More data for this Ligand-Target Pair				3D Structure (crystal)
Reverse transcriptase/RNaseH (Human immunodeficiency virus 1)	BDBM33415 (CHEMBL204900 \| pyrimidinol carboxylic acid, 7) Show SMILES OC(=O)c1nc(Cc2ccccc2)[nH]c(=O)c1O Show InChI	PDB MMDB UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.50E+3	n/a	n/a	n/a	n/a	8.0	20
Gilead Sciences Inc.					Assay Description Enzyme activity was measuring substrate hydrolysis of RNase H. The intact substrate has a low background fluorescent signal and provides up to 50-fol...				J Med Chem 52: 5781-4 (2009) Article DOI: 10.1021/jm900597q BindingDB Entry DOI: 10.7270/Q2TM78F2
Gilead Sciences Inc.					More data for this Ligand-Target Pair
Reverse transcriptase/RNaseH (Human immunodeficiency virus 1)	BDBM33412 (CHEMBL183852 \| N-hydroxy quinazolinedione, 4 \| US1...) Show SMILES On1c(=O)[nH]c2ccccc2c1=O Show InChI	PDB MMDB UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	6.00E+3	n/a	n/a	n/a	n/a	8.0	20
Gilead Sciences Inc.					Assay Description Enzyme activity was measuring substrate hydrolysis of RNase H. The intact substrate has a low background fluorescent signal and provides up to 50-fol...				J Med Chem 52: 5781-4 (2009) Article DOI: 10.1021/jm900597q BindingDB Entry DOI: 10.7270/Q2TM78F2
Gilead Sciences Inc.					More data for this Ligand-Target Pair
Reverse transcriptase/RNaseH (Human immunodeficiency virus 1)	BDBM33409 (alpha, gamma-diketo acid, 1) Show SMILES Show InChI	PDB MMDB UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	KEGG PC cid PC sid UniChem	Article PubMed	n/a	n/a	9.85E+3	n/a	n/a	n/a	n/a	8.0	20
Gilead Sciences Inc.					Assay Description Enzyme activity was measuring substrate hydrolysis of RNase H. The intact substrate has a low background fluorescent signal and provides up to 50-fol...				J Med Chem 52: 5781-4 (2009) Article DOI: 10.1021/jm900597q BindingDB Entry DOI: 10.7270/Q2TM78F2
Gilead Sciences Inc.					More data for this Ligand-Target Pair
Reverse transcriptase/RNaseH (Human immunodeficiency virus 1)	BDBM33416 (pyrimidinol carboxylic acid, 8) Show SMILES OC(=O)c1nc(CCc2ccccc2)[nH]c(=O)c1O Show InChI	PDB MMDB UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.02E+4	n/a	n/a	n/a	n/a	8.0	20
Gilead Sciences Inc.					Assay Description Enzyme activity was measuring substrate hydrolysis of RNase H. The intact substrate has a low background fluorescent signal and provides up to 50-fol...				J Med Chem 52: 5781-4 (2009) Article DOI: 10.1021/jm900597q BindingDB Entry DOI: 10.7270/Q2TM78F2
Gilead Sciences Inc.					More data for this Ligand-Target Pair
Reverse transcriptase/RNaseH (Human immunodeficiency virus 1)	BDBM33414 (CHEMBL440562 \| pyrimidinol carboxylic acid, 6) Show SMILES OC(=O)c1nc([nH]c(=O)c1O)-c1ccccc1 Show InChI	PDB MMDB UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.30E+4	n/a	n/a	n/a	n/a	8.0	20
Gilead Sciences Inc.					Assay Description Enzyme activity was measuring substrate hydrolysis of RNase H. The intact substrate has a low background fluorescent signal and provides up to 50-fol...				J Med Chem 52: 5781-4 (2009) Article DOI: 10.1021/jm900597q BindingDB Entry DOI: 10.7270/Q2TM78F2
Gilead Sciences Inc.					More data for this Ligand-Target Pair
Reverse transcriptase/RNaseH (Human immunodeficiency virus 1)	BDBM33413 (benzo[7]annulene-8-carboxylic acid, 5) Show SMILES OC(=O)c1cc(O)c(=O)c2c(O)c(O)ccc2c1 Show InChI	PDB MMDB UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	MCE PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	2.32E+4	n/a	n/a	n/a	n/a	8.0	20
Gilead Sciences Inc.					Assay Description Enzyme activity was measuring substrate hydrolysis of RNase H. The intact substrate has a low background fluorescent signal and provides up to 50-fol...				J Med Chem 52: 5781-4 (2009) Article DOI: 10.1021/jm900597q BindingDB Entry DOI: 10.7270/Q2TM78F2
Gilead Sciences Inc.					More data for this Ligand-Target Pair
Ribonuclease H1 (Homo sapiens (Human))	BDBM33419 (pyrimidinol carboxylic acid, 11) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	4.85E+4	n/a	n/a	n/a	n/a	8.0	20
Gilead Sciences Inc.					Assay Description Enzyme activity was measuring substrate hydrolysis of RNase H. The intact substrate has a low background fluorescent signal and provides up to 50-fol...				J Med Chem 52: 5781-4 (2009) Article DOI: 10.1021/jm900597q BindingDB Entry DOI: 10.7270/Q2TM78F2
Gilead Sciences Inc.					More data for this Ligand-Target Pair
Reverse transcriptase/RNaseH (Human immunodeficiency virus 1)	BDBM33420 (pyrimidinol carboxylic acid, 12) Show SMILES COC(=O)c1nc(Cc2ccccc2)[nH]c(=O)c1O Show InChI	PDB MMDB UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	7.20E+4	n/a	n/a	n/a	n/a	8.0	20
Gilead Sciences Inc.					Assay Description Enzyme activity was measuring substrate hydrolysis of RNase H. The intact substrate has a low background fluorescent signal and provides up to 50-fol...				J Med Chem 52: 5781-4 (2009) Article DOI: 10.1021/jm900597q BindingDB Entry DOI: 10.7270/Q2TM78F2
Gilead Sciences Inc.					More data for this Ligand-Target Pair
Ribonuclease H1 (Homo sapiens (Human))	BDBM33418 (pyrimidinol carboxylic acid, 10) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	MMDB PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	7.40E+4	n/a	n/a	n/a	n/a	8.0	20
Gilead Sciences Inc.					Assay Description Enzyme activity was measuring substrate hydrolysis of RNase H. The intact substrate has a low background fluorescent signal and provides up to 50-fol...				J Med Chem 52: 5781-4 (2009) Article DOI: 10.1021/jm900597q BindingDB Entry DOI: 10.7270/Q2TM78F2
Gilead Sciences Inc.					More data for this Ligand-Target Pair
Ribonuclease H1 (Homo sapiens (Human))	BDBM33414 (CHEMBL440562 \| pyrimidinol carboxylic acid, 6) Show SMILES OC(=O)c1nc([nH]c(=O)c1O)-c1ccccc1 Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	8.0	20
Gilead Sciences Inc.					Assay Description Enzyme activity was measuring substrate hydrolysis of RNase H. The intact substrate has a low background fluorescent signal and provides up to 50-fol...				J Med Chem 52: 5781-4 (2009) Article DOI: 10.1021/jm900597q BindingDB Entry DOI: 10.7270/Q2TM78F2
Gilead Sciences Inc.					More data for this Ligand-Target Pair
Ribonuclease H1 (Homo sapiens (Human))	BDBM33415 (CHEMBL204900 \| pyrimidinol carboxylic acid, 7) Show SMILES OC(=O)c1nc(Cc2ccccc2)[nH]c(=O)c1O Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	8.0	20
Gilead Sciences Inc.					Assay Description Enzyme activity was measuring substrate hydrolysis of RNase H. The intact substrate has a low background fluorescent signal and provides up to 50-fol...				J Med Chem 52: 5781-4 (2009) Article DOI: 10.1021/jm900597q BindingDB Entry DOI: 10.7270/Q2TM78F2
Gilead Sciences Inc.					More data for this Ligand-Target Pair
Ribonuclease H1 (Homo sapiens (Human))	BDBM33416 (pyrimidinol carboxylic acid, 8) Show SMILES OC(=O)c1nc(CCc2ccccc2)[nH]c(=O)c1O Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	8.0	20
Gilead Sciences Inc.					Assay Description Enzyme activity was measuring substrate hydrolysis of RNase H. The intact substrate has a low background fluorescent signal and provides up to 50-fol...				J Med Chem 52: 5781-4 (2009) Article DOI: 10.1021/jm900597q BindingDB Entry DOI: 10.7270/Q2TM78F2
Gilead Sciences Inc.					More data for this Ligand-Target Pair
Ribonuclease H1 (Homo sapiens (Human))	BDBM33417 (pyrimidinol carboxylic acid, 9) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	MMDB PC cid PC sid PDB UniChem Similars	Article PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	8.0	20
Gilead Sciences Inc.					Assay Description Enzyme activity was measuring substrate hydrolysis of RNase H. The intact substrate has a low background fluorescent signal and provides up to 50-fol...				J Med Chem 52: 5781-4 (2009) Article DOI: 10.1021/jm900597q BindingDB Entry DOI: 10.7270/Q2TM78F2
Gilead Sciences Inc.					More data for this Ligand-Target Pair
Nociceptin receptor (MOUSE)	BDBM50004178 (Nociceptin \| Nociceptin/orphanin FQ \| ORPHANIN FQ) Show SMILES Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase MCE KEGG PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	5.40	n/a	n/a	n/a	n/a
University of Ferrara Curated by ChEMBL					Assay Description Inhibition of electrically evoked contraction of mouse vas deferens				J Med Chem 48: 1421-7 (2005) Article DOI: 10.1021/jm040106v BindingDB Entry DOI: 10.7270/Q2J38WBW
University of Ferrara Curated by ChEMBL					More data for this Ligand-Target Pair
Nociceptin receptor (Homo sapiens (Human))	BDBM50475331 (CHEMBL411649) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	4.90	n/a	n/a	n/a	n/a
University of Ferrara Curated by ChEMBL					Assay Description Inhibition of forskolin stimulated cAMP levels in CHO cell membranes expressing the human NOP receptor (CHOhNOP)				J Med Chem 48: 1421-7 (2005) Article DOI: 10.1021/jm040106v BindingDB Entry DOI: 10.7270/Q2J38WBW
University of Ferrara Curated by ChEMBL					More data for this Ligand-Target Pair

Displayed 1 to 50 (of 77 total ) | Next | Last >>