Compile Data Set for Download or QSAR

Found 94 hits with Last Name = 'binda' and Initial = 'm'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Neuronal acetylcholine receptor subunit alpha-4 (Rattus norvegicus (Rat))	BDBM82070 (CAS_29790-52-1 | NICOTINE-L (BASE) | Nicotine-D sa...) Show SMILES CN1CCC[C@H]1c1cccnc1 |r| Show InChI InChI=1S/C10H14N2/c1-12-7-3-5-10(12)9-4-2-6-11-8-9/h2,4,6,8,10H,3,5,7H2,1H3/t10-/m0/s1	PDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase KEGG PC cid PC sid PDB UniChem Similars	PDB Article PubMed	4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Università di Milano Pietro Pratesi Curated by ChEMBL					Assay Description Displacement of [3H]epibatidine from alpha4beta2 nAchR in rat brain cortex membrane				Bioorg Med Chem Lett 19: 854-9 (2009) Article DOI: 10.1016/j.bmcl.2008.12.002 BindingDB Entry DOI: 10.7270/Q29K4B2T
					More data for this Ligand-Target Pair				3D Structure (crystal)
Neuronal acetylcholine receptor subunit alpha-4/beta-2 (Homo sapiens (Human))	BDBM86312 (CAS_84607 | DMCC | NSC_84607) Show SMILES CN(C)C(=O)OCC[N+](C)(C)C Show InChI InChI=1S/C8H19N2O2/c1-9(2)8(11)12-7-6-10(3,4)5/h6-7H2,1-5H3/q+1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	KEGG PC cid PC sid UniChem Patents Similars	Article PubMed	20	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ di Milano Curated by ChEMBL					Assay Description Binding affinity to alpha4beta2 nAChR (unknown origin)				Bioorg Med Chem Lett 23: 6481-5 (2013) Article DOI: 10.1016/j.bmcl.2013.09.023 BindingDB Entry DOI: 10.7270/Q22V2HKF
					More data for this Ligand-Target Pair
Neuronal acetylcholine receptor subunit alpha-4/beta-2 (Homo sapiens (Human))	BDBM82546 (CAS_14721-69-8 | MCC | N-methylcarbamylcholine | N...) Show SMILES CNC(=O)OCC[N+](C)(C)C Show InChI InChI=1S/C7H16N2O2/c1-8-7(10)11-6-5-9(2,3)4/h5-6H2,1-4H3/p+1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	KEGG PC cid PC sid UniChem Patents Similars	Article PubMed	23	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ di Milano Curated by ChEMBL					Assay Description Binding affinity to alpha4beta2 nAChR (unknown origin)				Bioorg Med Chem Lett 23: 6481-5 (2013) Article DOI: 10.1016/j.bmcl.2013.09.023 BindingDB Entry DOI: 10.7270/Q22V2HKF
					More data for this Ligand-Target Pair
Neuronal acetylcholine receptor subunit alpha-7 (Rattus norvegicus (Rat))	BDBM50114008 (CHEMBL3603931) Show SMILES CN1CC[C@H]1COc1cccc(O)c1 |r| Show InChI InChI=1S/C11H15NO2/c1-12-6-5-9(12)8-14-11-4-2-3-10(13)7-11/h2-4,7,9,13H,5-6,8H2,1H3/t9-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	29	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ degli Studi di Milano Curated by ChEMBL					Assay Description Displacement of [125I]]-alpha-bungarotoxin from alpha7 nAChR in rat hippocampus membranes by liquid scintillation counting method				J Med Chem 58: 6665-77 (2015) Article DOI: 10.1021/acs.jmedchem.5b00904 BindingDB Entry DOI: 10.7270/Q2CF9RX4
					More data for this Ligand-Target Pair
Neuronal acetylcholine receptor subunit alpha-7 (Rattus norvegicus (Rat))	BDBM50113482 (CHEMBL3603941) Show SMILES [H][C@]1(CCCN1C)[C@@H](C)Oc1cccc(O)c1 |r| Show InChI InChI=1S/C13H19NO2/c1-10(13-7-4-8-14(13)2)16-12-6-3-5-11(15)9-12/h3,5-6,9-10,13,15H,4,7-8H2,1-2H3/t10-,13+/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	57	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ degli Studi di Milano Curated by ChEMBL					Assay Description Displacement of [125I]]-alpha-bungarotoxin from alpha7 nAChR in rat hippocampus membranes by liquid scintillation counting method				J Med Chem 58: 6665-77 (2015) Article DOI: 10.1021/acs.jmedchem.5b00904 BindingDB Entry DOI: 10.7270/Q2CF9RX4
					More data for this Ligand-Target Pair
Neuronal acetylcholine receptor subunit alpha-7 (Rattus norvegicus (Rat))	BDBM50114006 (CHEMBL3603929) Show SMILES CN1CCC[C@H]1COc1cccc(O)c1 |r| Show InChI InChI=1S/C12H17NO2/c1-13-7-3-4-10(13)9-15-12-6-2-5-11(14)8-12/h2,5-6,8,10,14H,3-4,7,9H2,1H3/t10-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	119	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ degli Studi di Milano Curated by ChEMBL					Assay Description Displacement of [125I]]-alpha-bungarotoxin from alpha7 nAChR in rat hippocampus membranes by liquid scintillation counting method				J Med Chem 58: 6665-77 (2015) Article DOI: 10.1021/acs.jmedchem.5b00904 BindingDB Entry DOI: 10.7270/Q2CF9RX4
					More data for this Ligand-Target Pair
Neuronal acetylcholine receptor subunit alpha-4/beta-2 (Rattus norvegicus (Rat))	BDBM50259714 (CHEMBL4101001) Show SMILES CN1CCC[C@H]1c1cc2ccccc2o1 |r| Show InChI InChI=1S/C13H15NO/c1-14-8-4-6-11(14)13-9-10-5-2-3-7-12(10)15-13/h2-3,5,7,9,11H,4,6,8H2,1H3/t11-/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	160	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ degli Studi di Milano Curated by ChEMBL					Assay Description Displacement of [3H](-)cytisine from rat whole brain alpha4beta2 nAChR				Eur J Med Chem 125: 1132-1144 (2017) Article DOI: 10.1016/j.ejmech.2016.10.048 BindingDB Entry DOI: 10.7270/Q2PZ5C8H
					More data for this Ligand-Target Pair
Neuronal acetylcholine receptor subunit alpha-7 (Rattus norvegicus (Rat))	BDBM50114005 (CHEMBL3603930) Show SMILES Oc1cccc(OC[C@@H]2CCCN2)c1 |r| Show InChI InChI=1S/C11H15NO2/c13-10-4-1-5-11(7-10)14-8-9-3-2-6-12-9/h1,4-5,7,9,12-13H,2-3,6,8H2/t9-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	212	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ degli Studi di Milano Curated by ChEMBL					Assay Description Displacement of [125I]]-alpha-bungarotoxin from alpha7 nAChR in rat hippocampus membranes by liquid scintillation counting method				J Med Chem 58: 6665-77 (2015) Article DOI: 10.1021/acs.jmedchem.5b00904 BindingDB Entry DOI: 10.7270/Q2CF9RX4
					More data for this Ligand-Target Pair
Neuronal acetylcholine receptor subunit alpha-7 (Rattus norvegicus (Rat))	BDBM82070 (CAS_29790-52-1 | NICOTINE-L (BASE) | Nicotine-D sa...) Show SMILES CN1CCC[C@H]1c1cccnc1 |r| Show InChI InChI=1S/C10H14N2/c1-12-7-3-5-10(12)9-4-2-6-11-8-9/h2,4,6,8,10H,3,5,7H2,1H3/t10-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase KEGG PC cid PC sid PDB UniChem Similars	PDB Article PubMed	234	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Università di Milano Pietro Pratesi Curated by ChEMBL					Assay Description Displacement of [125I]alphaBungarotoxin from alpha7 nAchR in rat brain cortex membrane				Bioorg Med Chem Lett 19: 854-9 (2009) Article DOI: 10.1016/j.bmcl.2008.12.002 BindingDB Entry DOI: 10.7270/Q29K4B2T
					More data for this Ligand-Target Pair				3D Structure (crystal)
Neuronal acetylcholine receptor subunit alpha-7 (Rattus norvegicus (Rat))	BDBM82070 (CAS_29790-52-1 | NICOTINE-L (BASE) | Nicotine-D sa...) Show SMILES CN1CCC[C@H]1c1cccnc1 |r| Show InChI InChI=1S/C10H14N2/c1-12-7-3-5-10(12)9-4-2-6-11-8-9/h2,4,6,8,10H,3,5,7H2,1H3/t10-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase KEGG PC cid PC sid PDB UniChem Similars	PDB Article PubMed	234	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ degli Studi di Milano Curated by ChEMBL					Assay Description Displacement of [125I]]-alpha-bungarotoxin from alpha7 nAChR in rat hippocampus membranes by liquid scintillation counting method				J Med Chem 58: 6665-77 (2015) Article DOI: 10.1021/acs.jmedchem.5b00904 BindingDB Entry DOI: 10.7270/Q2CF9RX4
					More data for this Ligand-Target Pair				3D Structure (crystal)
Neuronal acetylcholine receptor subunit alpha-3/beta-4 (Homo sapiens (Human))	BDBM50113482 (CHEMBL3603941) Show SMILES [H][C@]1(CCCN1C)[C@@H](C)Oc1cccc(O)c1 |r| Show InChI InChI=1S/C13H19NO2/c1-10(13-7-4-8-14(13)2)16-12-6-3-5-11(15)9-12/h3,5-6,9-10,13,15H,4,7-8H2,1-2H3/t10-,13+/m1/s1	PDB KEGG UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	257	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ degli Studi di Milano Curated by ChEMBL					Assay Description Displacement of [3H]epibatidine from human alpha3beta4 nAChR expressed in HEK293 cells pretreated for 5 mins followed by [3H]epibatidine addition aft...				Eur J Med Chem 125: 1132-1144 (2017) Article DOI: 10.1016/j.ejmech.2016.10.048 BindingDB Entry DOI: 10.7270/Q2PZ5C8H
					More data for this Ligand-Target Pair
Neuronal acetylcholine receptor subunit alpha-4 (Rattus norvegicus (Rat))	BDBM50194315 ((2R,2'S)-2-(1-methyl-2-pyrrolidinyl)-1,4-benzodiox...) Show SMILES CN1CCC[C@H]1[C@@H]1COc2ccccc2O1 Show InChI InChI=1S/C13H17NO2/c1-14-8-4-5-10(14)13-9-15-11-6-2-3-7-12(11)16-13/h2-3,6-7,10,13H,4-5,8-9H2,1H3/t10-,13-/m0/s1	PDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	260	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Università di Milano Pietro Pratesi Curated by ChEMBL					Assay Description Displacement of [3H]epibatidine from alpha4beta2 nAchR in rat brain cortex membrane				Bioorg Med Chem Lett 19: 854-9 (2009) Article DOI: 10.1016/j.bmcl.2008.12.002 BindingDB Entry DOI: 10.7270/Q29K4B2T
					More data for this Ligand-Target Pair
Neuronal acetylcholine receptor subunit alpha-3/beta-4 (Homo sapiens (Human))	BDBM82070 (CAS_29790-52-1 | NICOTINE-L (BASE) | Nicotine-D sa...) Show SMILES CN1CCC[C@H]1c1cccnc1 |r| Show InChI InChI=1S/C10H14N2/c1-12-7-3-5-10(12)9-4-2-6-11-8-9/h2,4,6,8,10H,3,5,7H2,1H3/t10-/m0/s1	PDB KEGG UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	Purchase KEGG PC cid PC sid PDB UniChem Similars	Article PubMed	261	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ degli Studi di Milano Curated by ChEMBL					Assay Description Displacement of [3H]epibatidine from human alpha3beta4 nAChR expressed in HEK293 cells pretreated for 5 mins followed by [3H]epibatidine addition aft...				Eur J Med Chem 125: 1132-1144 (2017) Article DOI: 10.1016/j.ejmech.2016.10.048 BindingDB Entry DOI: 10.7270/Q2PZ5C8H
					More data for this Ligand-Target Pair
Neuronal acetylcholine receptor subunit alpha-3/beta-4 (Homo sapiens (Human))	BDBM50114015 (CHEMBL3603939) Show SMILES COc1ccc(O)cc1OC[C@@H]1CCCN1C |r| Show InChI InChI=1S/C13H19NO3/c1-14-7-3-4-10(14)9-17-13-8-11(15)5-6-12(13)16-2/h5-6,8,10,15H,3-4,7,9H2,1-2H3/t10-/m0/s1	PDB KEGG UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	271	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ degli Studi di Milano Curated by ChEMBL					Assay Description Displacement of [3H]epibatidine from human alpha3beta4 nAChR expressed in HEK293 cells pretreated for 5 mins followed by [3H]epibatidine addition aft...				Eur J Med Chem 125: 1132-1144 (2017) Article DOI: 10.1016/j.ejmech.2016.10.048 BindingDB Entry DOI: 10.7270/Q2PZ5C8H
					More data for this Ligand-Target Pair
Neuronal acetylcholine receptor subunit alpha-3/beta-4 (Homo sapiens (Human))	BDBM50357065 (CHEMBL1917232) Show SMILES CN1CCC[C@H]1[C@H]1COc2ccc(O)cc2O1 |r| Show InChI InChI=1S/C13H17NO3/c1-14-6-2-3-10(14)13-8-16-11-5-4-9(15)7-12(11)17-13/h4-5,7,10,13,15H,2-3,6,8H2,1H3/t10-,13+/m0/s1	PDB KEGG UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	310	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ degli Studi di Milano Curated by ChEMBL					Assay Description Displacement of [3H]epibatidine from human alpha3beta4 nAChR expressed in HEK293 cells pretreated for 5 mins followed by [3H]epibatidine addition aft...				Eur J Med Chem 125: 1132-1144 (2017) Article DOI: 10.1016/j.ejmech.2016.10.048 BindingDB Entry DOI: 10.7270/Q2PZ5C8H
					More data for this Ligand-Target Pair
Neuronal acetylcholine receptor subunit alpha-7 (Rattus norvegicus (Rat))	BDBM50114000 (CHEMBL3603933) Show SMILES CN1CCC[C@H]1COc1cncc(O)c1 |r| Show InChI InChI=1S/C11H16N2O2/c1-13-4-2-3-9(13)8-15-11-5-10(14)6-12-7-11/h5-7,9,14H,2-4,8H2,1H3/t9-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	321	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ degli Studi di Milano Curated by ChEMBL					Assay Description Displacement of [125I]]-alpha-bungarotoxin from alpha7 nAChR in rat hippocampus membranes by liquid scintillation counting method				J Med Chem 58: 6665-77 (2015) Article DOI: 10.1021/acs.jmedchem.5b00904 BindingDB Entry DOI: 10.7270/Q2CF9RX4
					More data for this Ligand-Target Pair
Neuronal acetylcholine receptor subunit alpha-7 (Rattus norvegicus (Rat))	BDBM50114004 (CHEMBL3603947) Show SMILES [H][C@]1(CCCN1C)[C@@H](C)Oc1cccnc1 |r| Show InChI InChI=1S/C12H18N2O/c1-10(12-6-4-8-14(12)2)15-11-5-3-7-13-9-11/h3,5,7,9-10,12H,4,6,8H2,1-2H3/t10-,12+/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	388	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ degli Studi di Milano Curated by ChEMBL					Assay Description Displacement of [125I]]-alpha-bungarotoxin from alpha7 nAChR in rat hippocampus membranes by liquid scintillation counting method				J Med Chem 58: 6665-77 (2015) Article DOI: 10.1021/acs.jmedchem.5b00904 BindingDB Entry DOI: 10.7270/Q2CF9RX4
					More data for this Ligand-Target Pair
Neuronal acetylcholine receptor subunit alpha-7 (Rattus norvegicus (Rat))	BDBM50357064 (CHEMBL1917231) Show SMILES CN1CCC[C@H]1[C@@H]1COc2ccc(O)cc2O1 |r| Show InChI InChI=1S/C13H17NO3/c1-14-6-2-3-10(14)13-8-16-11-5-4-9(15)7-12(11)17-13/h4-5,7,10,13,15H,2-3,6,8H2,1H3/t10-,13-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	427	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ degli Studi di Milano Curated by ChEMBL					Assay Description Displacement of [125I]alpha-bungarotoxin from alpha7 nAChR in Sprague-Dawley rat cerebral cortex by beta counting				J Med Chem 54: 7588-601 (2011) Article DOI: 10.1021/jm200937t BindingDB Entry DOI: 10.7270/Q2K64JGC
					More data for this Ligand-Target Pair
Neuronal acetylcholine receptor subunit alpha-4 (Rattus norvegicus (Rat))	BDBM50256279 ((2S,2'S)-2-(1-methyl-2-pyrrolidinyl)-1,4-benzodiox...) Show SMILES CN1CCC[C@H]1[C@H]1COc2ccccc2O1 |r| Show InChI InChI=1S/C13H17NO2/c1-14-8-4-5-10(14)13-9-15-11-6-2-3-7-12(11)16-13/h2-3,6-7,10,13H,4-5,8-9H2,1H3/t10-,13+/m0/s1	PDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	470	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Università di Milano Pietro Pratesi Curated by ChEMBL					Assay Description Displacement of [3H]epibatidine from alpha4beta2 nAchR in rat brain cortex membrane				Bioorg Med Chem Lett 19: 854-9 (2009) Article DOI: 10.1016/j.bmcl.2008.12.002 BindingDB Entry DOI: 10.7270/Q29K4B2T
					More data for this Ligand-Target Pair
Neuronal acetylcholine receptor subunit alpha-7 (Rattus norvegicus (Rat))	BDBM50114019 (CHEMBL3603942) Show SMILES [H][C@]1(CCCN1C)[C@H](C)Oc1cccc(O)c1 |r| Show InChI InChI=1S/C13H19NO2/c1-10(13-7-4-8-14(13)2)16-12-6-3-5-11(15)9-12/h3,5-6,9-10,13,15H,4,7-8H2,1-2H3/t10-,13-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	743	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ degli Studi di Milano Curated by ChEMBL					Assay Description Displacement of [125I]]-alpha-bungarotoxin from alpha7 nAChR in rat hippocampus membranes by liquid scintillation counting method				J Med Chem 58: 6665-77 (2015) Article DOI: 10.1021/acs.jmedchem.5b00904 BindingDB Entry DOI: 10.7270/Q2CF9RX4
					More data for this Ligand-Target Pair
Neuronal acetylcholine receptor subunit alpha-4/beta-2 (Homo sapiens (Human))	BDBM50004656 ((2-Carbamoyloxy-ethyl)-trimethyl-ammonium | (2-Car...) Show SMILES C[N+](C)(C)CCOC(N)=O Show InChI InChI=1S/C6H14N2O2/c1-8(2,3)4-5-10-6(7)9/h4-5H2,1-3H3,(H-,7,9)/p+1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank KEGG MMDB PC cid PC sid PDB UniChem Similars	Article PubMed	750	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ di Milano Curated by ChEMBL					Assay Description Binding affinity to alpha4beta2 nAChR (unknown origin)				Bioorg Med Chem Lett 23: 6481-5 (2013) Article DOI: 10.1016/j.bmcl.2013.09.023 BindingDB Entry DOI: 10.7270/Q22V2HKF
					More data for this Ligand-Target Pair
Neuronal acetylcholine receptor subunit alpha-7 (Rattus norvegicus (Rat))	BDBM50114015 (CHEMBL3603939) Show SMILES COc1ccc(O)cc1OC[C@@H]1CCCN1C |r| Show InChI InChI=1S/C13H19NO3/c1-14-7-3-4-10(14)9-17-13-8-11(15)5-6-12(13)16-2/h5-6,8,10,15H,3-4,7,9H2,1-2H3/t10-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.15E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ degli Studi di Milano Curated by ChEMBL					Assay Description Displacement of [125I]]-alpha-bungarotoxin from alpha7 nAChR in rat hippocampus membranes by liquid scintillation counting method				J Med Chem 58: 6665-77 (2015) Article DOI: 10.1021/acs.jmedchem.5b00904 BindingDB Entry DOI: 10.7270/Q2CF9RX4
					More data for this Ligand-Target Pair
Neuronal acetylcholine receptor subunit alpha-7 (Rattus norvegicus (Rat))	BDBM50114007 (CHEMBL3603932) Show SMILES Oc1cccc(OC[C@@H]2CCN2)c1 |r| Show InChI InChI=1S/C10H13NO2/c12-9-2-1-3-10(6-9)13-7-8-4-5-11-8/h1-3,6,8,11-12H,4-5,7H2/t8-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.20E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ degli Studi di Milano Curated by ChEMBL					Assay Description Displacement of [125I]]-alpha-bungarotoxin from alpha7 nAChR in rat hippocampus membranes by liquid scintillation counting method				J Med Chem 58: 6665-77 (2015) Article DOI: 10.1021/acs.jmedchem.5b00904 BindingDB Entry DOI: 10.7270/Q2CF9RX4
					More data for this Ligand-Target Pair
Neuronal acetylcholine receptor subunit alpha-3/beta-4 (Homo sapiens (Human))	BDBM50194315 ((2R,2'S)-2-(1-methyl-2-pyrrolidinyl)-1,4-benzodiox...) Show SMILES CN1CCC[C@H]1[C@@H]1COc2ccccc2O1 Show InChI InChI=1S/C13H17NO2/c1-14-8-4-5-10(14)13-9-15-11-6-2-3-7-12(11)16-13/h2-3,6-7,10,13H,4-5,8-9H2,1H3/t10-,13-/m0/s1	PDB KEGG UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.20E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ degli Studi di Milano Curated by ChEMBL					Assay Description Displacement of [3H]epibatidine from human alpha3beta4 nAChR expressed in HEK293 cells pretreated for 5 mins followed by [3H]epibatidine addition aft...				Eur J Med Chem 125: 1132-1144 (2017) Article DOI: 10.1016/j.ejmech.2016.10.048 BindingDB Entry DOI: 10.7270/Q2PZ5C8H
					More data for this Ligand-Target Pair
Neuronal acetylcholine receptor subunit alpha-7 (Rattus norvegicus (Rat))	BDBM50357067 (CHEMBL1917234) Show SMILES CN1CCC[C@@H]1[C@@H]1COc2ccc(O)cc2O1 |r| Show InChI InChI=1S/C13H17NO3/c1-14-6-2-3-10(14)13-8-16-11-5-4-9(15)7-12(11)17-13/h4-5,7,10,13,15H,2-3,6,8H2,1H3/t10-,13+/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.30E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ degli Studi di Milano Curated by ChEMBL					Assay Description Displacement of [125I]alpha-bungarotoxin from alpha7 nAChR in Sprague-Dawley rat cerebral cortex by beta counting				J Med Chem 54: 7588-601 (2011) Article DOI: 10.1021/jm200937t BindingDB Entry DOI: 10.7270/Q2K64JGC
					More data for this Ligand-Target Pair
Neuronal acetylcholine receptor subunit alpha-4 (Rattus norvegicus (Rat))	BDBM50256280 ((2R,2'S)-2-(2,3-dihydrobenzo[b][1,4]dioxin-2-yl)py...) Show SMILES C1CN[C@@H](C1)[C@@H]1COc2ccccc2O1 |r| Show InChI InChI=1S/C12H15NO2/c1-2-6-11-10(5-1)14-8-12(15-11)9-4-3-7-13-9/h1-2,5-6,9,12-13H,3-4,7-8H2/t9-,12-/m0/s1	PDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	2.10E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Università di Milano Pietro Pratesi Curated by ChEMBL					Assay Description Displacement of [3H]epibatidine from alpha4beta2 nAchR in rat brain cortex membrane				Bioorg Med Chem Lett 19: 854-9 (2009) Article DOI: 10.1016/j.bmcl.2008.12.002 BindingDB Entry DOI: 10.7270/Q29K4B2T
					More data for this Ligand-Target Pair
Neuronal acetylcholine receptor subunit alpha-4 (Rattus norvegicus (Rat))	BDBM50256181 ((5S,2'S)-5-(1-methyl-2-pyrrolidinyl)oxazolidinone ...) Show SMILES CN1CCC[C@H]1[C@@H]1CNC(=O)O1 |r| Show InChI InChI=1S/C8H14N2O2/c1-10-4-2-3-6(10)7-5-9-8(11)12-7/h6-7H,2-5H2,1H3,(H,9,11)/t6-,7-/m0/s1	PDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	2.70E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Università di Milano Pietro Pratesi Curated by ChEMBL					Assay Description Displacement of [3H]epibatidine from alpha4beta2 nAchR in rat brain cortex membrane				Bioorg Med Chem Lett 19: 854-9 (2009) Article DOI: 10.1016/j.bmcl.2008.12.002 BindingDB Entry DOI: 10.7270/Q29K4B2T
					More data for this Ligand-Target Pair
Neuronal acetylcholine receptor subunit alpha-7 (Rattus norvegicus (Rat))	BDBM50357071 (CHEMBL1917237) Show SMILES Oc1ccc2OC[C@H](Oc2c1)[C@H]1CCCN1 |r| Show InChI InChI=1S/C12H15NO3/c14-8-3-4-10-11(6-8)16-12(7-15-10)9-2-1-5-13-9/h3-4,6,9,12-14H,1-2,5,7H2/t9-,12+/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	3.00E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ degli Studi di Milano Curated by ChEMBL					Assay Description Displacement of [125I]alpha-bungarotoxin from alpha7 nAChR in Sprague-Dawley rat cerebral cortex by beta counting				J Med Chem 54: 7588-601 (2011) Article DOI: 10.1021/jm200937t BindingDB Entry DOI: 10.7270/Q2K64JGC
					More data for this Ligand-Target Pair
Neuronal acetylcholine receptor subunit alpha-7 (Rattus norvegicus (Rat))	BDBM50113999 (CHEMBL3603934) Show SMILES Oc1cncc(OC[C@@H]2CCCN2)c1 |r| Show InChI InChI=1S/C10H14N2O2/c13-9-4-10(6-11-5-9)14-7-8-2-1-3-12-8/h4-6,8,12-13H,1-3,7H2/t8-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	3.50E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ degli Studi di Milano Curated by ChEMBL					Assay Description Displacement of [125I]]-alpha-bungarotoxin from alpha7 nAChR in rat hippocampus membranes by liquid scintillation counting method				J Med Chem 58: 6665-77 (2015) Article DOI: 10.1021/acs.jmedchem.5b00904 BindingDB Entry DOI: 10.7270/Q2CF9RX4
					More data for this Ligand-Target Pair
Neuronal acetylcholine receptor subunit alpha-7 (Rattus norvegicus (Rat))	BDBM50357066 (CHEMBL1917233) Show SMILES CN1CCC[C@@H]1[C@H]1COc2ccc(O)cc2O1 |r| Show InChI InChI=1S/C13H17NO3/c1-14-6-2-3-10(14)13-8-16-11-5-4-9(15)7-12(11)17-13/h4-5,7,10,13,15H,2-3,6,8H2,1H3/t10-,13-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	4.50E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ degli Studi di Milano Curated by ChEMBL					Assay Description Displacement of [125I]alpha-bungarotoxin from alpha7 nAChR in Sprague-Dawley rat cerebral cortex by beta counting				J Med Chem 54: 7588-601 (2011) Article DOI: 10.1021/jm200937t BindingDB Entry DOI: 10.7270/Q2K64JGC
					More data for this Ligand-Target Pair
Neuronal acetylcholine receptor subunit alpha-4/beta-2 (Homo sapiens (Human))	BDBM86310 (DMCAE) Show SMILES CN(C)CCOC(=O)N(C)C Show InChI InChI=1S/C7H16N2O2/c1-8(2)5-6-11-7(10)9(3)4/h5-6H2,1-4H3	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	5.70E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ di Milano Curated by ChEMBL					Assay Description Binding affinity to alpha4beta2 nAChR (unknown origin)				Bioorg Med Chem Lett 23: 6481-5 (2013) Article DOI: 10.1016/j.bmcl.2013.09.023 BindingDB Entry DOI: 10.7270/Q22V2HKF
					More data for this Ligand-Target Pair
Neuronal acetylcholine receptor subunit alpha-3/beta-4 (Homo sapiens (Human))	BDBM50259712 (CHEMBL4061221) Show SMILES [H][C@]1(CCCN1C)[C@]1([H])COc2ccncc2O1 |r| Show InChI InChI=1S/C12H16N2O2/c1-14-6-2-3-9(14)12-8-15-10-4-5-13-7-11(10)16-12/h4-5,7,9,12H,2-3,6,8H2,1H3/t9-,12-/m0/s1	PDB KEGG UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	5.80E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ degli Studi di Milano Curated by ChEMBL					Assay Description Displacement of [3H]epibatidine from human alpha3beta4 nAChR expressed in HEK293 cells pretreated for 5 mins followed by [3H]epibatidine addition aft...				Eur J Med Chem 125: 1132-1144 (2017) Article DOI: 10.1016/j.ejmech.2016.10.048 BindingDB Entry DOI: 10.7270/Q2PZ5C8H
					More data for this Ligand-Target Pair
Neuronal acetylcholine receptor subunit alpha-7 (Rattus norvegicus (Rat))	BDBM50357074 (CHEMBL1917240) Show SMILES CC(C)Oc1ccc2OC[C@H](Oc2c1)[C@@H]1CCCN1C |r| Show InChI InChI=1S/C16H23NO3/c1-11(2)19-12-6-7-14-15(9-12)20-16(10-18-14)13-5-4-8-17(13)3/h6-7,9,11,13,16H,4-5,8,10H2,1-3H3/t13-,16-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	6.10E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ degli Studi di Milano Curated by ChEMBL					Assay Description Displacement of [125I]alpha-bungarotoxin from alpha7 nAChR in Sprague-Dawley rat cerebral cortex by beta counting				J Med Chem 54: 7588-601 (2011) Article DOI: 10.1021/jm200937t BindingDB Entry DOI: 10.7270/Q2K64JGC
					More data for this Ligand-Target Pair
Neuronal acetylcholine receptor subunit alpha-7 (Rattus norvegicus (Rat))	BDBM50114003 (CHEMBL3603948) Show SMILES [H][C@]1(CCCN1C)[C@H](C)Oc1cccnc1 |r| Show InChI InChI=1S/C12H18N2O/c1-10(12-6-4-8-14(12)2)15-11-5-3-7-13-9-11/h3,5,7,9-10,12H,4,6,8H2,1-2H3/t10-,12-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	6.10E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ degli Studi di Milano Curated by ChEMBL					Assay Description Displacement of [125I]]-alpha-bungarotoxin from alpha7 nAChR in rat hippocampus membranes by liquid scintillation counting method				J Med Chem 58: 6665-77 (2015) Article DOI: 10.1021/acs.jmedchem.5b00904 BindingDB Entry DOI: 10.7270/Q2CF9RX4
					More data for this Ligand-Target Pair
Neuronal acetylcholine receptor subunit alpha-3/beta-4 (Homo sapiens (Human))	BDBM50256279 ((2S,2'S)-2-(1-methyl-2-pyrrolidinyl)-1,4-benzodiox...) Show SMILES CN1CCC[C@H]1[C@H]1COc2ccccc2O1 |r| Show InChI InChI=1S/C13H17NO2/c1-14-8-4-5-10(14)13-9-15-11-6-2-3-7-12(11)16-13/h2-3,6-7,10,13H,4-5,8-9H2,1H3/t10-,13+/m0/s1	PDB KEGG UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	8.20E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ degli Studi di Milano Curated by ChEMBL					Assay Description Displacement of [3H]epibatidine from human alpha3beta4 nAChR expressed in HEK293 cells pretreated for 5 mins followed by [3H]epibatidine addition aft...				Eur J Med Chem 125: 1132-1144 (2017) Article DOI: 10.1016/j.ejmech.2016.10.048 BindingDB Entry DOI: 10.7270/Q2PZ5C8H
					More data for this Ligand-Target Pair
Neuronal acetylcholine receptor subunit alpha-7 (Rattus norvegicus (Rat))	BDBM50114016 (CHEMBL3603938) Show SMILES CC(Oc1ccccc1)C1CCCN1C Show InChI InChI=1S/C13H19NO/c1-11(13-9-6-10-14(13)2)15-12-7-4-3-5-8-12/h3-5,7-8,11,13H,6,9-10H2,1-2H3	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	8.90E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ degli Studi di Milano Curated by ChEMBL					Assay Description Displacement of [125I]]-alpha-bungarotoxin from alpha7 nAChR in rat hippocampus membranes by liquid scintillation counting method				J Med Chem 58: 6665-77 (2015) Article DOI: 10.1021/acs.jmedchem.5b00904 BindingDB Entry DOI: 10.7270/Q2CF9RX4
					More data for this Ligand-Target Pair
Neuronal acetylcholine receptor subunit alpha-3/beta-4 (Homo sapiens (Human))	BDBM50259715 (CHEMBL4076895) Show SMILES [H][C@]1(CCCN1C)[C@@]1([H])COc2ccncc2O1 |r| Show InChI InChI=1S/C12H16N2O2/c1-14-6-2-3-9(14)12-8-15-10-4-5-13-7-11(10)16-12/h4-5,7,9,12H,2-3,6,8H2,1H3/t9-,12+/m0/s1	PDB KEGG UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	8.90E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ degli Studi di Milano Curated by ChEMBL					Assay Description Displacement of [3H]epibatidine from human alpha3beta4 nAChR expressed in HEK293 cells pretreated for 5 mins followed by [3H]epibatidine addition aft...				Eur J Med Chem 125: 1132-1144 (2017) Article DOI: 10.1016/j.ejmech.2016.10.048 BindingDB Entry DOI: 10.7270/Q2PZ5C8H
					More data for this Ligand-Target Pair
Neuronal acetylcholine receptor subunit alpha-7 (Rattus norvegicus (Rat))	BDBM50114011 (CHEMBL3603945) Show SMILES COc1ccncc1OC[C@@H]1CCCN1C |r| Show InChI InChI=1S/C12H18N2O2/c1-14-7-3-4-10(14)9-16-12-8-13-6-5-11(12)15-2/h5-6,8,10H,3-4,7,9H2,1-2H3/t10-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	9.40E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ degli Studi di Milano Curated by ChEMBL					Assay Description Displacement of [125I]]-alpha-bungarotoxin from alpha7 nAChR in rat hippocampus membranes by liquid scintillation counting method				J Med Chem 58: 6665-77 (2015) Article DOI: 10.1021/acs.jmedchem.5b00904 BindingDB Entry DOI: 10.7270/Q2CF9RX4
					More data for this Ligand-Target Pair
Neuronal acetylcholine receptor subunit alpha-4 (Rattus norvegicus (Rat))	BDBM50256282 ((2R,2'R))-2-(2,3-dihydrobenzo[b][1,4]dioxin-2-yl)p...) Show SMILES C1CN[C@H](C1)[C@@H]1COc2ccccc2O1 |r| Show InChI InChI=1S/C12H15NO2/c1-2-6-11-10(5-1)14-8-12(15-11)9-4-3-7-13-9/h1-2,5-6,9,12-13H,3-4,7-8H2/t9-,12+/m1/s1	PDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.16E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Università di Milano Pietro Pratesi Curated by ChEMBL					Assay Description Displacement of [3H]epibatidine from alpha4beta2 nAchR in rat brain cortex membrane				Bioorg Med Chem Lett 19: 854-9 (2009) Article DOI: 10.1016/j.bmcl.2008.12.002 BindingDB Entry DOI: 10.7270/Q29K4B2T
					More data for this Ligand-Target Pair
Neuronal acetylcholine receptor subunit alpha-7 (Rattus norvegicus (Rat))	BDBM50357076 (CHEMBL1917224) Show SMILES CN1CCC[C@H]1[C@H]1COc2ccc(CO)cc2O1 |r| Show InChI InChI=1S/C14H19NO3/c1-15-6-2-3-11(15)14-9-17-12-5-4-10(8-16)7-13(12)18-14/h4-5,7,11,14,16H,2-3,6,8-9H2,1H3/t11-,14+/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.20E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ degli Studi di Milano Curated by ChEMBL					Assay Description Displacement of [125I]alpha-bungarotoxin from alpha7 nAChR in Sprague-Dawley rat cerebral cortex by beta counting				J Med Chem 54: 7588-601 (2011) Article DOI: 10.1021/jm200937t BindingDB Entry DOI: 10.7270/Q2K64JGC
					More data for this Ligand-Target Pair
Neuronal acetylcholine receptor subunit alpha-4 (Rattus norvegicus (Rat))	BDBM50194314 ((2S,2'R)-2-(1-methyl-2-pyrrolidinyl)-1,4-benzodiox...) Show SMILES CN1CCC[C@@H]1[C@H]1COc2ccccc2O1 Show InChI InChI=1S/C13H17NO2/c1-14-8-4-5-10(14)13-9-15-11-6-2-3-7-12(11)16-13/h2-3,6-7,10,13H,4-5,8-9H2,1H3/t10-,13-/m1/s1	PDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.25E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Università di Milano Pietro Pratesi Curated by ChEMBL					Assay Description Displacement of [3H]epibatidine from alpha4beta2 nAchR in rat brain cortex membrane				Bioorg Med Chem Lett 19: 854-9 (2009) Article DOI: 10.1016/j.bmcl.2008.12.002 BindingDB Entry DOI: 10.7270/Q29K4B2T
					More data for this Ligand-Target Pair
Neuronal acetylcholine receptor subunit alpha-4 (Rattus norvegicus (Rat))	BDBM50256335 ((2S,2'S-2-(2,3-dihydrobenzo[b][1,4]dioxin-2-yl)pyr...) Show SMILES C1CN[C@@H](C1)[C@H]1COc2ccccc2O1 |r| Show InChI InChI=1S/C12H15NO2/c1-2-6-11-10(5-1)14-8-12(15-11)9-4-3-7-13-9/h1-2,5-6,9,12-13H,3-4,7-8H2/t9-,12+/m0/s1	PDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.44E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Università di Milano Pietro Pratesi Curated by ChEMBL					Assay Description Displacement of [3H]epibatidine from alpha4beta2 nAchR in rat brain cortex membrane				Bioorg Med Chem Lett 19: 854-9 (2009) Article DOI: 10.1016/j.bmcl.2008.12.002 BindingDB Entry DOI: 10.7270/Q29K4B2T
					More data for this Ligand-Target Pair
Neuronal acetylcholine receptor subunit alpha-7 (Rattus norvegicus (Rat))	BDBM50256279 ((2S,2'S)-2-(1-methyl-2-pyrrolidinyl)-1,4-benzodiox...) Show SMILES CN1CCC[C@H]1[C@H]1COc2ccccc2O1 |r| Show InChI InChI=1S/C13H17NO2/c1-14-8-4-5-10(14)13-9-15-11-6-2-3-7-12(11)16-13/h2-3,6-7,10,13H,4-5,8-9H2,1H3/t10-,13+/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.46E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Università di Milano Pietro Pratesi Curated by ChEMBL					Assay Description Displacement of [125I]alphaBungarotoxin from alpha7 nAchR in rat brain cortex membrane				Bioorg Med Chem Lett 19: 854-9 (2009) Article DOI: 10.1016/j.bmcl.2008.12.002 BindingDB Entry DOI: 10.7270/Q29K4B2T
					More data for this Ligand-Target Pair
Neuronal acetylcholine receptor subunit alpha-7 (Rattus norvegicus (Rat))	BDBM50256281 ((2S,2'R-2-(2,3-dihydrobenzo[b][1,4]dioxin-2-yl)pyr...) Show SMILES C1CN[C@H](C1)[C@H]1COc2ccccc2O1 |r| Show InChI InChI=1S/C12H15NO2/c1-2-6-11-10(5-1)14-8-12(15-11)9-4-3-7-13-9/h1-2,5-6,9,12-13H,3-4,7-8H2/t9-,12-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.47E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Università di Milano Pietro Pratesi Curated by ChEMBL					Assay Description Displacement of [125I]alphaBungarotoxin from alpha7 nAchR in rat brain cortex membrane				Bioorg Med Chem Lett 19: 854-9 (2009) Article DOI: 10.1016/j.bmcl.2008.12.002 BindingDB Entry DOI: 10.7270/Q29K4B2T
					More data for this Ligand-Target Pair
Neuronal acetylcholine receptor subunit alpha-7 (Rattus norvegicus (Rat))	BDBM50256278 ((2R,2'R)-2-(1-methyl-2-pyrrolidinyl)-1,4-benzodiox...) Show SMILES CN1CCC[C@@H]1[C@@H]1COc2ccccc2O1 |r| Show InChI InChI=1S/C13H17NO2/c1-14-8-4-5-10(14)13-9-15-11-6-2-3-7-12(11)16-13/h2-3,6-7,10,13H,4-5,8-9H2,1H3/t10-,13+/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.48E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Università di Milano Pietro Pratesi Curated by ChEMBL					Assay Description Displacement of [125I]alphaBungarotoxin from alpha7 nAchR in rat brain cortex membrane				Bioorg Med Chem Lett 19: 854-9 (2009) Article DOI: 10.1016/j.bmcl.2008.12.002 BindingDB Entry DOI: 10.7270/Q29K4B2T
					More data for this Ligand-Target Pair
Neuronal acetylcholine receptor subunit alpha-7 (Rattus norvegicus (Rat))	BDBM50114014 (CHEMBL3603937) Show SMILES [H][C@]1(CCCN1C)[C@@H](C)Oc1ccccc1 |r| Show InChI InChI=1S/C13H19NO/c1-11(13-9-6-10-14(13)2)15-12-7-4-3-5-8-12/h3-5,7-8,11,13H,6,9-10H2,1-2H3/t11-,13+/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.52E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ degli Studi di Milano Curated by ChEMBL					Assay Description Displacement of [125I]]-alpha-bungarotoxin from alpha7 nAChR in rat hippocampus membranes by liquid scintillation counting method				J Med Chem 58: 6665-77 (2015) Article DOI: 10.1021/acs.jmedchem.5b00904 BindingDB Entry DOI: 10.7270/Q2CF9RX4
					More data for this Ligand-Target Pair
Neuronal acetylcholine receptor subunit alpha-3/beta-4 (Homo sapiens (Human))	BDBM50259713 (CHEMBL4095303) Show SMILES [H][C@]1(CCCN1C)[C@]1([H])COc2ncccc2O1 |r| Show InChI InChI=1S/C12H16N2O2/c1-14-7-3-4-9(14)11-8-15-12-10(16-11)5-2-6-13-12/h2,5-6,9,11H,3-4,7-8H2,1H3/t9-,11-/m0/s1	PDB KEGG UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	1.62E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ degli Studi di Milano Curated by ChEMBL					Assay Description Displacement of [3H]epibatidine from human alpha3beta4 nAChR expressed in HEK293 cells pretreated for 5 mins followed by [3H]epibatidine addition aft...				Eur J Med Chem 125: 1132-1144 (2017) Article DOI: 10.1016/j.ejmech.2016.10.048 BindingDB Entry DOI: 10.7270/Q2PZ5C8H
					More data for this Ligand-Target Pair
Neuronal acetylcholine receptor subunit alpha-7 (Rattus norvegicus (Rat))	BDBM50357065 (CHEMBL1917232) Show SMILES CN1CCC[C@H]1[C@H]1COc2ccc(O)cc2O1 |r| Show InChI InChI=1S/C13H17NO3/c1-14-6-2-3-10(14)13-8-16-11-5-4-9(15)7-12(11)17-13/h4-5,7,10,13,15H,2-3,6,8H2,1H3/t10-,13+/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	2.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ degli Studi di Milano Curated by ChEMBL					Assay Description Displacement of [125I]alpha-bungarotoxin from alpha7 nAChR in Sprague-Dawley rat cerebral cortex by beta counting				J Med Chem 54: 7588-601 (2011) Article DOI: 10.1021/jm200937t BindingDB Entry DOI: 10.7270/Q2K64JGC
					More data for this Ligand-Target Pair
Neuronal acetylcholine receptor subunit alpha-7 (Rattus norvegicus (Rat))	BDBM50256181 ((5S,2'S)-5-(1-methyl-2-pyrrolidinyl)oxazolidinone ...) Show SMILES CN1CCC[C@H]1[C@@H]1CNC(=O)O1 |r| Show InChI InChI=1S/C8H14N2O2/c1-10-4-2-3-6(10)7-5-9-8(11)12-7/h6-7H,2-5H2,1H3,(H,9,11)/t6-,7-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	2.10E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Università di Milano Pietro Pratesi Curated by ChEMBL					Assay Description Displacement of [125I]alphaBungarotoxin from alpha7 nAchR in rat brain cortex membrane				Bioorg Med Chem Lett 19: 854-9 (2009) Article DOI: 10.1016/j.bmcl.2008.12.002 BindingDB Entry DOI: 10.7270/Q29K4B2T
					More data for this Ligand-Target Pair
Neuronal acetylcholine receptor subunit alpha-7 (Rattus norvegicus (Rat))	BDBM50194315 ((2R,2'S)-2-(1-methyl-2-pyrrolidinyl)-1,4-benzodiox...) Show SMILES CN1CCC[C@H]1[C@@H]1COc2ccccc2O1 Show InChI InChI=1S/C13H17NO2/c1-14-8-4-5-10(14)13-9-15-11-6-2-3-7-12(11)16-13/h2-3,6-7,10,13H,4-5,8-9H2,1H3/t10-,13-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	2.10E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Università di Milano Pietro Pratesi Curated by ChEMBL					Assay Description Displacement of [125I]alphaBungarotoxin from alpha7 nAchR in rat brain cortex membrane				Bioorg Med Chem Lett 19: 854-9 (2009) Article DOI: 10.1016/j.bmcl.2008.12.002 BindingDB Entry DOI: 10.7270/Q29K4B2T
					More data for this Ligand-Target Pair

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