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| Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Thyroid hormone receptor beta (Homo sapiens (Human)) | BDBM18864 (3-[4-(4-hydroxy-3-iodophenoxy)-3,5-diiodophenyl]pr...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet  | Purchase PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 0.0190 | n/a | n/a | n/a | n/a | 7.0 | 4 |
Karo Bio AB | Assay Description IC50 is the concentration of each compound required to inhibit 50% binding of 125I-T3 to hTRbeta. | J Med Chem 46: 1580-8 (2003) Article DOI: 10.1021/jm021080f BindingDB Entry DOI: 10.7270/Q20K26TG | |||||||||||
| More data for this Ligand-Target Pair |  3D Structure (docked) | ||||||||||||
| Thyroid hormone receptor beta (Homo sapiens (Human)) | BDBM18865 (3-{3,5-dibromo-4-[4-hydroxy-3-(propan-2-yl)phenoxy...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL MMDB PC cid PC sid PDB UniChem Patents Similars | MMDB PDB Article PubMed | n/a | n/a | 0.0250 | n/a | n/a | n/a | n/a | 7.0 | 4 |
Karo Bio AB | Assay Description IC50 is the concentration of each compound required to inhibit 50% binding of 125I-T3 to hTRbeta. | J Med Chem 46: 1580-8 (2003) Article DOI: 10.1021/jm021080f BindingDB Entry DOI: 10.7270/Q20K26TG | |||||||||||
| More data for this Ligand-Target Pair | 3D Structure (crystal) | ||||||||||||
| Thyroid hormone receptor alpha (Homo sapiens (Human)) | BDBM18864 (3-[4-(4-hydroxy-3-iodophenoxy)-3,5-diiodophenyl]pr...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 0.0410 | n/a | n/a | n/a | n/a | 7.0 | 4 |
Karo Bio AB | Assay Description IC50 is the concentration of each compound required to inhibit 50% binding of 125I-T3 to hTRalpha. | J Med Chem 46: 1580-8 (2003) Article DOI: 10.1021/jm021080f BindingDB Entry DOI: 10.7270/Q20K26TG | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Thyroid hormone receptor beta (Homo sapiens (Human)) | BDBM18862 (2-[4-(4-hydroxy-3-iodophenoxy)-3,5-diiodophenyl]ac...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL DrugBank MCE MMDB PC cid PC sid PDB UniChem Patents | MMDB PDB Article PubMed | n/a | n/a | 0.0480 | n/a | n/a | n/a | n/a | 7.0 | 4 |
Karo Bio AB | Assay Description IC50 is the concentration of each compound required to inhibit 50% binding of 125I-T3 to hTRbeta. | J Med Chem 46: 1580-8 (2003) Article DOI: 10.1021/jm021080f BindingDB Entry DOI: 10.7270/Q20K26TG | |||||||||||
| More data for this Ligand-Target Pair | 3D Structure (crystal) | ||||||||||||
| Thyroid hormone receptor beta (Homo sapiens (Human)) | BDBM18867 (2-{3,5-dibromo-4-[4-hydroxy-3-(propan-2-yl)phenoxy...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Patents | Article PubMed | n/a | n/a | 0.0950 | n/a | 0.200 | n/a | n/a | 7.0 | 4 |
Karo Bio AB | Assay Description IC50 is the concentration of each compound required to inhibit 50% binding of 125I-T3 to hTRbeta. EC50 is the concentration of compound required to r... | J Med Chem 46: 1580-8 (2003) Article DOI: 10.1021/jm021080f BindingDB Entry DOI: 10.7270/Q20K26TG | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Thyroid hormone receptor alpha (Homo sapiens (Human)) | BDBM18865 (3-{3,5-dibromo-4-[4-hydroxy-3-(propan-2-yl)phenoxy...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL MMDB PC cid PC sid PDB UniChem Patents Similars | Article PubMed | n/a | n/a | 0.100 | n/a | n/a | n/a | n/a | 7.0 | 4 |
Karo Bio AB | Assay Description IC50 is the concentration of each compound required to inhibit 50% binding of 125I-T3 to hTRalpha. | J Med Chem 46: 1580-8 (2003) Article DOI: 10.1021/jm021080f BindingDB Entry DOI: 10.7270/Q20K26TG | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Thyroid hormone receptor beta (Homo sapiens (Human)) | BDBM18863 ((2R)-2-amino-3-{4-[4-hydroxy-3-(propan-2-yl)phenox...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 0.110 | n/a | n/a | n/a | n/a | 7.0 | 4 |
Karo Bio AB | Assay Description IC50 is the concentration of each compound required to inhibit 50% binding of 125I-T3 to hTRbeta. | J Med Chem 46: 1580-8 (2003) Article DOI: 10.1021/jm021080f BindingDB Entry DOI: 10.7270/Q20K26TG | |||||||||||
| More data for this Ligand-Target Pair | 3D Structure (docked) | ||||||||||||
| Thyroid hormone receptor alpha (Homo sapiens (Human)) | BDBM18862 (2-[4-(4-hydroxy-3-iodophenoxy)-3,5-diiodophenyl]ac...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL DrugBank MCE MMDB PC cid PC sid PDB UniChem Patents | PDB Article PubMed | n/a | n/a | 0.140 | n/a | n/a | n/a | n/a | 7.0 | 4 |
Karo Bio AB | Assay Description IC50 is the concentration of each compound required to inhibit 50% binding of 125I-T3 to hTRalpha. | J Med Chem 46: 1580-8 (2003) Article DOI: 10.1021/jm021080f BindingDB Entry DOI: 10.7270/Q20K26TG | |||||||||||
| More data for this Ligand-Target Pair | 3D Structure (crystal) | ||||||||||||
| Thyroid hormone receptor alpha (Homo sapiens (Human)) | BDBM18863 ((2R)-2-amino-3-{4-[4-hydroxy-3-(propan-2-yl)phenox...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 0.140 | n/a | n/a | n/a | n/a | 7.0 | 4 |
Karo Bio AB | Assay Description IC50 is the concentration of each compound required to inhibit 50% binding of 125I-T3 to hTRalpha. | J Med Chem 46: 1580-8 (2003) Article DOI: 10.1021/jm021080f BindingDB Entry DOI: 10.7270/Q20K26TG | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Thyroid hormone receptor beta (Homo sapiens (Human)) | BDBM18870 (3-{3,5-dichloro-4-[4-hydroxy-3-(propan-2-yl)phenox...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Patents | Article PubMed | n/a | n/a | 0.150 | n/a | 0.280 | n/a | n/a | 7.0 | 4 |
Karo Bio AB | Assay Description IC50 is the concentration of each compound required to inhibit 50% binding of 125I-T3 to hTRbeta. EC50 is the concentration of compound required to r... | J Med Chem 46: 1580-8 (2003) Article DOI: 10.1021/jm021080f BindingDB Entry DOI: 10.7270/Q20K26TG | |||||||||||
| More data for this Ligand-Target Pair | 3D Structure (docked) | ||||||||||||
| Thyroid hormone receptor alpha (Homo sapiens (Human)) | BDBM18860 ((2R)-2-amino-3-[4-(4-hydroxy-3-iodophenoxy)-3,5-di...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars | DrugBank PDB Article PubMed | n/a | n/a | 0.240 | n/a | n/a | n/a | n/a | 7.0 | 4 |
Karo Bio AB | Assay Description IC50 is the concentration of each compound required to inhibit 50% binding of 125I-T3 to hTRalpha. | J Med Chem 46: 1580-8 (2003) Article DOI: 10.1021/jm021080f BindingDB Entry DOI: 10.7270/Q20K26TG | |||||||||||
| More data for this Ligand-Target Pair | 3D Structure (crystal) | ||||||||||||
| Thyroid hormone receptor beta (Homo sapiens (Human)) | BDBM18860 ((2R)-2-amino-3-[4-(4-hydroxy-3-iodophenoxy)-3,5-di...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars | DrugBank PDB Article PubMed | n/a | n/a | 0.260 | n/a | n/a | n/a | n/a | 7.0 | 4 |
Karo Bio AB | Assay Description IC50 is the concentration of each compound required to inhibit 50% binding of 125I-T3 to hTRbeta. | J Med Chem 46: 1580-8 (2003) Article DOI: 10.1021/jm021080f BindingDB Entry DOI: 10.7270/Q20K26TG | |||||||||||
| More data for this Ligand-Target Pair | 3D Structure (crystal) | ||||||||||||
| Thyroid hormone receptor alpha (Homo sapiens (Human)) | BDBM18870 (3-{3,5-dichloro-4-[4-hydroxy-3-(propan-2-yl)phenox...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Patents | Article PubMed | n/a | n/a | 0.760 | n/a | 0.300 | n/a | n/a | 7.0 | 4 |
Karo Bio AB | Assay Description IC50 is the concentration of each compound required to inhibit 50% binding of 125I-T3 to hTRalpha. EC50 is the concentration of compound required to ... | J Med Chem 46: 1580-8 (2003) Article DOI: 10.1021/jm021080f BindingDB Entry DOI: 10.7270/Q20K26TG | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Thyroid hormone receptor beta (Homo sapiens (Human)) | BDBM18869 (2-{3,5-dichloro-4-[4-hydroxy-3-(propan-2-yl)phenox...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL DrugBank MCE MMDB PC cid PC sid PDB UniChem Patents Similars | MMDB PDB Article PubMed | n/a | n/a | 1.10 | n/a | 3.5 | n/a | n/a | 7.0 | 4 |
Karo Bio AB | Assay Description IC50 is the concentration of each compound required to inhibit 50% binding of 125I-T3 to hTRbeta. EC50 is the concentration of compound required to r... | J Med Chem 46: 1580-8 (2003) Article DOI: 10.1021/jm021080f BindingDB Entry DOI: 10.7270/Q20K26TG | |||||||||||
| More data for this Ligand-Target Pair | 3D Structure (crystal) | ||||||||||||
| Thyroid hormone receptor alpha (Homo sapiens (Human)) | BDBM18867 (2-{3,5-dibromo-4-[4-hydroxy-3-(propan-2-yl)phenoxy...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Patents | Article PubMed | n/a | n/a | 1.40 | n/a | 0.380 | n/a | n/a | 7.0 | 4 |
Karo Bio AB | Assay Description IC50 is the concentration of each compound required to inhibit 50% binding of 125I-T3 to hTRalpha. EC50 is the concentration of compound required to ... | J Med Chem 46: 1580-8 (2003) Article DOI: 10.1021/jm021080f BindingDB Entry DOI: 10.7270/Q20K26TG | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Thyroid hormone receptor beta (Homo sapiens (Human)) | BDBM18866 (3,5-dibromo-4-[4-hydroxy-3-(propan-2-yl)phenoxy]be...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 2.10 | n/a | n/a | n/a | n/a | 7.0 | 4 |
Karo Bio AB | Assay Description IC50 is the concentration of each compound required to inhibit 50% binding of 125I-T3 to hTRbeta. | J Med Chem 46: 1580-8 (2003) Article DOI: 10.1021/jm021080f BindingDB Entry DOI: 10.7270/Q20K26TG | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Thyroid hormone receptor alpha (Homo sapiens (Human)) | BDBM18866 (3,5-dibromo-4-[4-hydroxy-3-(propan-2-yl)phenoxy]be...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 9.70 | n/a | n/a | n/a | n/a | 7.0 | 4 |
Karo Bio AB | Assay Description IC50 is the concentration of each compound required to inhibit 50% binding of 125I-T3 to hTRalpha. | J Med Chem 46: 1580-8 (2003) Article DOI: 10.1021/jm021080f BindingDB Entry DOI: 10.7270/Q20K26TG | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Thyroid hormone receptor beta (Homo sapiens (Human)) | BDBM18868 (3,5-dichloro-4-[4-hydroxy-3-(propan-2-yl)phenoxy]b...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Patents | Article PubMed | n/a | n/a | 21 | n/a | 150 | n/a | n/a | 7.0 | 4 |
Karo Bio AB | Assay Description IC50 is the concentration of each compound required to inhibit 50% binding of 125I-T3 to hTRbeta. EC50 is the concentration of compound required to r... | J Med Chem 46: 1580-8 (2003) Article DOI: 10.1021/jm021080f BindingDB Entry DOI: 10.7270/Q20K26TG | |||||||||||
| More data for this Ligand-Target Pair | 3D Structure (docked) | ||||||||||||
| Thyroid hormone receptor alpha (Homo sapiens (Human)) | BDBM18869 (2-{3,5-dichloro-4-[4-hydroxy-3-(propan-2-yl)phenox...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL DrugBank MCE MMDB PC cid PC sid PDB UniChem Patents Similars | PDB Article PubMed | n/a | n/a | 25 | n/a | 11 | n/a | n/a | 7.0 | 4 |
Karo Bio AB | Assay Description IC50 is the concentration of each compound required to inhibit 50% binding of 125I-T3 to hTRalpha. EC50 is the concentration of compound required to ... | J Med Chem 46: 1580-8 (2003) Article DOI: 10.1021/jm021080f BindingDB Entry DOI: 10.7270/Q20K26TG | |||||||||||
| More data for this Ligand-Target Pair | 3D Structure (crystal) | ||||||||||||
| Thyroid hormone receptor alpha (Homo sapiens (Human)) | BDBM18868 (3,5-dichloro-4-[4-hydroxy-3-(propan-2-yl)phenoxy]b...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Patents | Article PubMed | n/a | n/a | 130 | n/a | 190 | n/a | n/a | 7.0 | 4 |
Karo Bio AB | Assay Description IC50 is the concentration of each compound required to inhibit 50% binding of 125I-T3 to hTRalpha. EC50 is the concentration of compound required to ... | J Med Chem 46: 1580-8 (2003) Article DOI: 10.1021/jm021080f BindingDB Entry DOI: 10.7270/Q20K26TG | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Thyroid hormone receptor beta (Homo sapiens (Human)) | BDBM18887 (3,5-Dibromo-4-alkoxyphenylalkanoic Acid, 9k | 3-[3...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 190 | n/a | 0.120 | n/a | n/a | 7.0 | 4 |
Karo Bio AB | Assay Description IC50 is the concentration of each compound required to inhibit 50% binding of 125I-T3 to hTRbeta. EC50 is the concentration of compound required to i... | J Med Chem 48: 3114-7 (2005) Article DOI: 10.1021/jm050004k BindingDB Entry DOI: 10.7270/Q2M906XW | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Thyroid hormone receptor beta (Homo sapiens (Human)) | BDBM18906 (3,5-Dibromo-4-alkoxyphenylalkanoic Acid, 9i | 3-[3...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 360 | n/a | 1 | n/a | n/a | 7.0 | 4 |
Karo Bio AB | Assay Description IC50 is the concentration of each compound required to inhibit 50% binding of 125I-T3 to hTRbeta. EC50 is the concentration of compound required to i... | J Med Chem 48: 3114-7 (2005) Article DOI: 10.1021/jm050004k BindingDB Entry DOI: 10.7270/Q2M906XW | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Thyroid hormone receptor alpha (Homo sapiens (Human)) | BDBM18887 (3,5-Dibromo-4-alkoxyphenylalkanoic Acid, 9k | 3-[3...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 460 | n/a | 0.530 | n/a | n/a | 7.0 | 4 |
Karo Bio AB | Assay Description IIC50 is the concentration of each compound required to inhibit 50% binding of 125I-T3 to hTRalpha. EC50 is the concentration of compound required to... | J Med Chem 48: 3114-7 (2005) Article DOI: 10.1021/jm050004k BindingDB Entry DOI: 10.7270/Q2M906XW | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Thyroid hormone receptor beta (Homo sapiens (Human)) | BDBM18904 (2-[3,5-dibromo-4-(cyclohexylmethoxy)phenyl]acetic ...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 770 | n/a | 0.520 | n/a | n/a | 7.0 | 4 |
Karo Bio AB | Assay Description IC50 is the concentration of each compound required to inhibit 50% binding of 125I-T3 to hTRbeta. EC50 is the concentration of compound required to i... | J Med Chem 48: 3114-7 (2005) Article DOI: 10.1021/jm050004k BindingDB Entry DOI: 10.7270/Q2M906XW | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Thyroid hormone receptor beta (Homo sapiens (Human)) | BDBM18903 (2-[3,5-dibromo-4-(2-ethylbutoxy)phenyl]acetic acid...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 800 | n/a | 0.700 | n/a | n/a | 7.0 | 4 |
Karo Bio AB | Assay Description IC50 is the concentration of each compound required to inhibit 50% binding of 125I-T3 to hTRbeta. EC50 is the concentration of compound required to i... | J Med Chem 48: 3114-7 (2005) Article DOI: 10.1021/jm050004k BindingDB Entry DOI: 10.7270/Q2M906XW | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Thyroid hormone receptor beta (Homo sapiens (Human)) | BDBM18907 (3,5-Dibromo-4-alkoxyphenylalkanoic Acid, 9j | 3-[3...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 810 | n/a | n/a | n/a | n/a | 7.0 | 4 |
Karo Bio AB | Assay Description IC50 is the concentration of each compound required to inhibit 50% binding of 125I-T3 to hTRbeta. EC50 is the concentration of compound required to i... | J Med Chem 48: 3114-7 (2005) Article DOI: 10.1021/jm050004k BindingDB Entry DOI: 10.7270/Q2M906XW | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Thyroid hormone receptor alpha (Homo sapiens (Human)) | BDBM18908 (3,5-dichloro-4-(2-chloro-4-nitrophenoxy)-N-[(3,5-d...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 930 | n/a | n/a | n/a | n/a | 7.0 | 4 |
Karo Bio AB | Assay Description IC50 is the concentration of each compound required to inhibit 50% binding of 125I-T3 to hTRalpha. | J Med Chem 41: 2503-12 (1998) Article DOI: 10.1021/jm9708691 BindingDB Entry DOI: 10.7270/Q2GM85KW | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Thyroid hormone receptor alpha (Homo sapiens (Human)) | BDBM18906 (3,5-Dibromo-4-alkoxyphenylalkanoic Acid, 9i | 3-[3...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 1.10E+3 | n/a | 0.600 | n/a | n/a | 7.0 | 4 |
Karo Bio AB | Assay Description IIC50 is the concentration of each compound required to inhibit 50% binding of 125I-T3 to hTRalpha. EC50 is the concentration of compound required to... | J Med Chem 48: 3114-7 (2005) Article DOI: 10.1021/jm050004k BindingDB Entry DOI: 10.7270/Q2M906XW | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Thyroid hormone receptor beta (Homo sapiens (Human)) | BDBM18902 (2-[3,5-dibromo-4-(hexyloxy)phenyl]acetic acid | 3,...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 1.50E+3 | n/a | 0.800 | n/a | n/a | 7.0 | 4 |
Karo Bio AB | Assay Description IC50 is the concentration of each compound required to inhibit 50% binding of 125I-T3 to hTRbeta. EC50 is the concentration of compound required to i... | J Med Chem 48: 3114-7 (2005) Article DOI: 10.1021/jm050004k BindingDB Entry DOI: 10.7270/Q2M906XW | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Thyroid hormone receptor alpha (Homo sapiens (Human)) | BDBM18907 (3,5-Dibromo-4-alkoxyphenylalkanoic Acid, 9j | 3-[3...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 1.60E+3 | n/a | n/a | n/a | n/a | 7.0 | 4 |
Karo Bio AB | Assay Description IIC50 is the concentration of each compound required to inhibit 50% binding of 125I-T3 to hTRalpha. EC50 is the concentration of compound required to... | J Med Chem 48: 3114-7 (2005) Article DOI: 10.1021/jm050004k BindingDB Entry DOI: 10.7270/Q2M906XW | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Thyroid hormone receptor alpha (Homo sapiens (Human)) | BDBM18910 (3,5-dichloro-4-(2-chloro-4-nitrophenoxy)-N-(2-chlo...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 1.80E+3 | n/a | n/a | n/a | n/a | 7.0 | 4 |
Karo Bio AB | Assay Description IC50 is the concentration of each compound required to inhibit 50% binding of 125I-T3 to hTRalpha. | J Med Chem 41: 2503-12 (1998) Article DOI: 10.1021/jm9708691 BindingDB Entry DOI: 10.7270/Q2GM85KW | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Thyroid hormone receptor beta (Homo sapiens (Human)) | BDBM18905 (3,5-Dibromo-4-alkoxyphenylalkanoic Acid, 9h | 3-[3...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 1.80E+3 | n/a | n/a | n/a | n/a | 7.0 | 4 |
Karo Bio AB | Assay Description IC50 is the concentration of each compound required to inhibit 50% binding of 125I-T3 to hTRbeta. EC50 is the concentration of compound required to i... | J Med Chem 48: 3114-7 (2005) Article DOI: 10.1021/jm050004k BindingDB Entry DOI: 10.7270/Q2M906XW | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Thyroid hormone receptor beta (Homo sapiens (Human)) | BDBM18901 (2-[3,5-dibromo-4-(3-methylbutoxy)phenyl]acetic aci...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 1.80E+3 | n/a | n/a | n/a | n/a | 7.0 | 4 |
Karo Bio AB | Assay Description IC50 is the concentration of each compound required to inhibit 50% binding of 125I-T3 to hTRbeta. EC50 is the concentration of compound required to i... | J Med Chem 48: 3114-7 (2005) Article DOI: 10.1021/jm050004k BindingDB Entry DOI: 10.7270/Q2M906XW | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Thyroid hormone receptor beta (Homo sapiens (Human)) | BDBM18899 (2-(3,5-dibromo-4-butoxyphenyl)acetic acid | 3,5-Di...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 1.90E+3 | n/a | n/a | n/a | n/a | 7.0 | 4 |
Karo Bio AB | Assay Description IC50 is the concentration of each compound required to inhibit 50% binding of 125I-T3 to hTRbeta. EC50 is the concentration of compound required to i... | J Med Chem 48: 3114-7 (2005) Article DOI: 10.1021/jm050004k BindingDB Entry DOI: 10.7270/Q2M906XW | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Thyroid hormone receptor alpha (Homo sapiens (Human)) | BDBM18904 (2-[3,5-dibromo-4-(cyclohexylmethoxy)phenyl]acetic ...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 2.70E+3 | n/a | 0.420 | n/a | n/a | 7.0 | 4 |
Karo Bio AB | Assay Description IIC50 is the concentration of each compound required to inhibit 50% binding of 125I-T3 to hTRalpha. EC50 is the concentration of compound required to... | J Med Chem 48: 3114-7 (2005) Article DOI: 10.1021/jm050004k BindingDB Entry DOI: 10.7270/Q2M906XW | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Thyroid hormone receptor alpha (Homo sapiens (Human)) | BDBM18905 (3,5-Dibromo-4-alkoxyphenylalkanoic Acid, 9h | 3-[3...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 4.40E+3 | n/a | n/a | n/a | n/a | 7.0 | 4 |
Karo Bio AB | Assay Description IIC50 is the concentration of each compound required to inhibit 50% binding of 125I-T3 to hTRalpha. EC50 is the concentration of compound required to... | J Med Chem 48: 3114-7 (2005) Article DOI: 10.1021/jm050004k BindingDB Entry DOI: 10.7270/Q2M906XW | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Thyroid hormone receptor alpha (Homo sapiens (Human)) | BDBM18902 (2-[3,5-dibromo-4-(hexyloxy)phenyl]acetic acid | 3,...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 5.20E+3 | n/a | 0.700 | n/a | n/a | 7.0 | 4 |
Karo Bio AB | Assay Description IIC50 is the concentration of each compound required to inhibit 50% binding of 125I-T3 to hTRalpha. EC50 is the concentration of compound required to... | J Med Chem 48: 3114-7 (2005) Article DOI: 10.1021/jm050004k BindingDB Entry DOI: 10.7270/Q2M906XW | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Thyroid hormone receptor beta (Homo sapiens (Human)) | BDBM18900 (2-[3,5-dibromo-4-(pentyloxy)phenyl]acetic acid | 3...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 5.70E+3 | n/a | n/a | n/a | n/a | 7.0 | 4 |
Karo Bio AB | Assay Description IC50 is the concentration of each compound required to inhibit 50% binding of 125I-T3 to hTRbeta. EC50 is the concentration of compound required to i... | J Med Chem 48: 3114-7 (2005) Article DOI: 10.1021/jm050004k BindingDB Entry DOI: 10.7270/Q2M906XW | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Thyroid hormone receptor alpha (Homo sapiens (Human)) | BDBM18903 (2-[3,5-dibromo-4-(2-ethylbutoxy)phenyl]acetic acid...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 6.90E+3 | n/a | 0.820 | n/a | n/a | 7.0 | 4 |
Karo Bio AB | Assay Description IIC50 is the concentration of each compound required to inhibit 50% binding of 125I-T3 to hTRalpha. EC50 is the concentration of compound required to... | J Med Chem 48: 3114-7 (2005) Article DOI: 10.1021/jm050004k BindingDB Entry DOI: 10.7270/Q2M906XW | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Thyroid hormone receptor alpha (Homo sapiens (Human)) | BDBM18901 (2-[3,5-dibromo-4-(3-methylbutoxy)phenyl]acetic aci...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 1.30E+4 | n/a | n/a | n/a | n/a | 7.0 | 4 |
Karo Bio AB | Assay Description IIC50 is the concentration of each compound required to inhibit 50% binding of 125I-T3 to hTRalpha. EC50 is the concentration of compound required to... | J Med Chem 48: 3114-7 (2005) Article DOI: 10.1021/jm050004k BindingDB Entry DOI: 10.7270/Q2M906XW | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Thyroid hormone receptor alpha (Homo sapiens (Human)) | BDBM18911 (3-nitro-N-[4-({4-[(3-nitrobenzene)amido]phenyl}met...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 1.81E+4 | n/a | n/a | n/a | n/a | 7.0 | 4 |
Karo Bio AB | Assay Description IC50 is the concentration of each compound required to inhibit 50% binding of 125I-T3 to hTRalpha. | J Med Chem 41: 2503-12 (1998) Article DOI: 10.1021/jm9708691 BindingDB Entry DOI: 10.7270/Q2GM85KW | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Thyroid hormone receptor alpha (Homo sapiens (Human)) | BDBM18900 (2-[3,5-dibromo-4-(pentyloxy)phenyl]acetic acid | 3...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 2.00E+4 | n/a | n/a | n/a | n/a | 7.0 | 4 |
Karo Bio AB | Assay Description IIC50 is the concentration of each compound required to inhibit 50% binding of 125I-T3 to hTRalpha. EC50 is the concentration of compound required to... | J Med Chem 48: 3114-7 (2005) Article DOI: 10.1021/jm050004k BindingDB Entry DOI: 10.7270/Q2M906XW | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Thyroid hormone receptor alpha (Homo sapiens (Human)) | BDBM18899 (2-(3,5-dibromo-4-butoxyphenyl)acetic acid | 3,5-Di...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 2.60E+4 | n/a | n/a | n/a | n/a | 7.0 | 4 |
Karo Bio AB | Assay Description IIC50 is the concentration of each compound required to inhibit 50% binding of 125I-T3 to hTRalpha. EC50 is the concentration of compound required to... | J Med Chem 48: 3114-7 (2005) Article DOI: 10.1021/jm050004k BindingDB Entry DOI: 10.7270/Q2M906XW | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Thyroid hormone receptor beta (Homo sapiens (Human)) | BDBM18898 (2-(3,5-dibromo-4-ethoxyphenyl)acetic acid | 3,5-Di...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 3.20E+4 | n/a | n/a | n/a | n/a | 7.0 | 4 |
Karo Bio AB | Assay Description IC50 is the concentration of each compound required to inhibit 50% binding of 125I-T3 to hTRbeta. EC50 is the concentration of compound required to i... | J Med Chem 48: 3114-7 (2005) Article DOI: 10.1021/jm050004k BindingDB Entry DOI: 10.7270/Q2M906XW | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Thyroid hormone receptor alpha (Homo sapiens (Human)) | BDBM18909 (3,5-dichloro-4-(2-chloro-4-nitrophenoxy)-N-(pyridi...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 3.90E+4 | n/a | n/a | n/a | n/a | 7.0 | 4 |
Karo Bio AB | Assay Description IC50 is the concentration of each compound required to inhibit 50% binding of 125I-T3 to hTRalpha. | J Med Chem 41: 2503-12 (1998) Article DOI: 10.1021/jm9708691 BindingDB Entry DOI: 10.7270/Q2GM85KW | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Thyroid hormone receptor alpha (Homo sapiens (Human)) | BDBM18912 (4-[(5-{[2-(2,4-dichlorophenyl)-2-oxoethyl]sulfanyl...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 6.90E+4 | n/a | n/a | n/a | n/a | 7.0 | 4 |
Karo Bio AB | Assay Description IC50 is the concentration of each compound required to inhibit 50% binding of 125I-T3 to hTRalpha. | J Med Chem 41: 2503-12 (1998) Article DOI: 10.1021/jm9708691 BindingDB Entry DOI: 10.7270/Q2GM85KW | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Thyroid hormone receptor alpha (Homo sapiens (Human)) | BDBM18898 (2-(3,5-dibromo-4-ethoxyphenyl)acetic acid | 3,5-Di...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 1.60E+5 | n/a | n/a | n/a | n/a | 7.0 | 4 |
Karo Bio AB | Assay Description IIC50 is the concentration of each compound required to inhibit 50% binding of 125I-T3 to hTRalpha. EC50 is the concentration of compound required to... | J Med Chem 48: 3114-7 (2005) Article DOI: 10.1021/jm050004k BindingDB Entry DOI: 10.7270/Q2M906XW | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
