Compile Data Set for Download or QSAR

Found 1282 hits with Last Name = 'blough' and Initial = 'b'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Sodium-dependent serotonin transporter (Rattus norvegicus (rat))	BDBM50046732 ((R)-3-(4-Chloro-phenyl)-8-aza-bicyclo[3.2.1]octane...) Show SMILES COC(=O)C1C2CCC(CC1c1ccc(Cl)cc1)N2 |THB:2:4:18:6.7,11:10:18:6.7| Show InChI InChI=1S/C15H18ClNO2/c1-19-15(18)14-12(8-11-6-7-13(14)17-11)9-2-4-10(16)5-3-9/h2-5,11-14,17H,6-8H2,1H3	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	0.380	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Research Triangle Institute Curated by ChEMBL					Assay Description Displacement of [3H]paroxetine from serotonin transporter (5-HT) of rat cerebral cortex				J Med Chem 48: 3852-7 (2005) Article DOI: 10.1021/jm058164j BindingDB Entry DOI: 10.7270/Q2M909FV
					More data for this Ligand-Target Pair
Sodium-dependent serotonin transporter (Rattus norvegicus (rat))	BDBM50046732 ((R)-3-(4-Chloro-phenyl)-8-aza-bicyclo[3.2.1]octane...) Show SMILES COC(=O)C1C2CCC(CC1c1ccc(Cl)cc1)N2 |THB:2:4:18:6.7,11:10:18:6.7| Show InChI InChI=1S/C15H18ClNO2/c1-19-15(18)14-12(8-11-6-7-13(14)17-11)9-2-4-10(16)5-3-9/h2-5,11-14,17H,6-8H2,1H3	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	0.380	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Research Triangle Institute Curated by ChEMBL					Assay Description Displacement of [3H]paroxetine from serotonin transporter (5-HT) of rat cerebral cortex				J Med Chem 48: 3852-7 (2005) Article DOI: 10.1021/jm058164j BindingDB Entry DOI: 10.7270/Q2M909FV
					More data for this Ligand-Target Pair
Transporter (Rattus norvegicus)	BDBM50168041 (3-(3-Fluoro-4-methyl-phenyl)-8-aza-bicyclo[3.2.1]o...) Show SMILES COC(=O)C1C2CCC(CC1c1ccc(C)c(F)c1)N2 |THB:2:4:19:6.7| Show InChI InChI=1S/C16H20FNO2/c1-9-3-4-10(7-13(9)17)12-8-11-5-6-14(18-11)15(12)16(19)20-2/h3-4,7,11-12,14-15,18H,5-6,8H2,1-2H3	Reactome pathway KEGG UniProtKB/TrEMBL GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	0.430	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Research Triangle Institute Curated by ChEMBL					Assay Description Displacement of [3H]nisoxetine from norepinephrine transporter (NET) of rat cerebral cortex				J Med Chem 48: 3852-7 (2005) Article DOI: 10.1021/jm058164j BindingDB Entry DOI: 10.7270/Q2M909FV
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2B (Homo sapiens (Human))	BDBM86237 (CAS_8226 | METHYLERGONOVINE | NSC_8226) Show SMILES CCC(CO)NC(=O)C1CN(C)C2Cc3c[nH]c4cccc(C2=C1)c34 |c:23| Show InChI InChI=1S/C20H25N3O2/c1-3-14(11-24)22-20(25)13-7-16-15-5-4-6-17-19(15)12(9-21-17)8-18(16)23(2)10-13/h4-7,9,13-14,18,21,24H,3,8,10-11H2,1-2H3,(H,22,25)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid PDB UniChem Similars	Article PubMed	0.800	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Case Western Reserve University Curated by PDSP Ki Database									Mol Pharmacol 63: 1223-9 (2003) Article DOI: 10.1124/mol.63.6.1223 BindingDB Entry DOI: 10.7270/Q2FN14SJ
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2B (Homo sapiens (Human))	BDBM10755 (14C-5-hydroxy tryptamine creatinine disulfate | 2-...) Show SMILES NCCc1c[nH]c2ccc(O)cc12 Show InChI InChI=1S/C10H12N2O/c11-4-3-7-6-12-10-2-1-8(13)5-9(7)10/h1-2,5-6,12-13H,3-4,11H2	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE KEGG PC cid PC sid PDB UniChem Similars	Article PubMed	1	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Case Western Reserve University Curated by PDSP Ki Database									Mol Pharmacol 63: 1223-9 (2003) Article DOI: 10.1124/mol.63.6.1223 BindingDB Entry DOI: 10.7270/Q2FN14SJ
					More data for this Ligand-Target Pair
Sodium-dependent serotonin transporter (Homo sapiens (Human))	BDBM50191330 (4,5,6,7,8,9,10,11,13,17a,18,19,20,21,22,22a-hexade...) Show SMILES CN1C2CCC1C1COC(=O)CCCCCCCCC(=O)Nc3ccc(cc3)C1C2 |TLB:7:6:1:3.4,THB:25:28:1:3.4| Show InChI InChI=1S/C25H36N2O3/c1-27-20-14-15-23(27)22-17-30-25(29)9-7-5-3-2-4-6-8-24(28)26-19-12-10-18(11-13-19)21(22)16-20/h10-13,20-23H,2-9,14-17H2,1H3,(H,26,28)	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.90	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Research Triangle Institute Curated by ChEMBL					Assay Description Displacement of [3H]paroxetine from human 5HTT				J Med Chem 49: 4589-94 (2006) Article DOI: 10.1021/jm060287w BindingDB Entry DOI: 10.7270/Q28053DM
					More data for this Ligand-Target Pair
Transporter (Rattus norvegicus)	BDBM50168044 (3-(3,5-Difluoro-phenyl)-8-aza-bicyclo[3.2.1]octane...) Show SMILES COC(=O)C1C2CCC(CC1c1cc(F)cc(F)c1)N2 |THB:2:4:19:6.7| Show InChI InChI=1S/C15H17F2NO2/c1-20-15(19)14-12(7-11-2-3-13(14)18-11)8-4-9(16)6-10(17)5-8/h4-6,11-14,18H,2-3,7H2,1H3	Reactome pathway KEGG UniProtKB/TrEMBL GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	2.05	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Research Triangle Institute Curated by ChEMBL					Assay Description Displacement of [3H]nisoxetine from norepinephrine transporter (NET) of rat cerebral cortex				J Med Chem 48: 3852-7 (2005) Article DOI: 10.1021/jm058164j BindingDB Entry DOI: 10.7270/Q2M909FV
					More data for this Ligand-Target Pair
Transporter (Rattus norvegicus)	BDBM50168042 (3-(4-Fluoro-3-methyl-phenyl)-8-aza-bicyclo[3.2.1]o...) Show SMILES COC(=O)C1C2CCC(CC1c1ccc(F)c(C)c1)N2 |THB:2:4:19:6.7| Show InChI InChI=1S/C16H20FNO2/c1-9-7-10(3-5-13(9)17)12-8-11-4-6-14(18-11)15(12)16(19)20-2/h3,5,7,11-12,14-15,18H,4,6,8H2,1-2H3	Reactome pathway KEGG UniProtKB/TrEMBL GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	2.12	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Research Triangle Institute Curated by ChEMBL					Assay Description Displacement of [3H]nisoxetine from norepinephrine transporter (NET) of rat cerebral cortex				J Med Chem 48: 3852-7 (2005) Article DOI: 10.1021/jm058164j BindingDB Entry DOI: 10.7270/Q2M909FV
					More data for this Ligand-Target Pair
Sodium-dependent serotonin transporter (Rattus norvegicus (rat))	BDBM50118185 ((3S,8R)-3-(4-Ethyl-phenyl)-8-methyl-8-aza-bicyclo[...) Show SMILES CCc1ccc(cc1)[C@H]1C[C@H]2CCC(C1C(=O)OC)N2C |THB:15:14:19:12.11,5:8:19:12.11,20:19:14.8.9:12.11| Show InChI InChI=1S/C18H25NO2/c1-4-12-5-7-13(8-6-12)15-11-14-9-10-16(19(14)2)17(15)18(20)21-3/h5-8,14-17H,4,9-11H2,1-3H3/t14-,15-,16?,17?/m1/s1	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	2.58	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Research Triangle Institute Curated by ChEMBL					Assay Description Tested for the binding affinity towards Serotonin transporter in rat midbrain tissue by displacing [3H]paroxetine radioligand				J Med Chem 45: 4029-37 (2002) BindingDB Entry DOI: 10.7270/Q20P10RR
					More data for this Ligand-Target Pair
Transporter (Rattus norvegicus)	BDBM50168047 (3-(3,4-Difluoro-phenyl)-8-aza-bicyclo[3.2.1]octane...) Show SMILES COC(=O)C1C2CCC(CC1c1ccc(F)c(F)c1)N2 |THB:2:4:19:6.7| Show InChI InChI=1S/C15H17F2NO2/c1-20-15(19)14-10(7-9-3-5-13(14)18-9)8-2-4-11(16)12(17)6-8/h2,4,6,9-10,13-14,18H,3,5,7H2,1H3	Reactome pathway KEGG UniProtKB/TrEMBL GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	2.60	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Research Triangle Institute Curated by ChEMBL					Assay Description Displacement of [3H]nisoxetine from norepinephrine transporter (NET) of rat cerebral cortex				J Med Chem 48: 3852-7 (2005) Article DOI: 10.1021/jm058164j BindingDB Entry DOI: 10.7270/Q2M909FV
					More data for this Ligand-Target Pair
Transporter (Rattus norvegicus)	BDBM50046732 ((R)-3-(4-Chloro-phenyl)-8-aza-bicyclo[3.2.1]octane...) Show SMILES COC(=O)C1C2CCC(CC1c1ccc(Cl)cc1)N2 |THB:2:4:18:6.7,11:10:18:6.7| Show InChI InChI=1S/C15H18ClNO2/c1-19-15(18)14-12(8-11-6-7-13(14)17-11)9-2-4-10(16)5-3-9/h2-5,11-14,17H,6-8H2,1H3	Reactome pathway KEGG UniProtKB/TrEMBL GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	3.10	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Research Triangle Institute Curated by ChEMBL					Assay Description Displacement of [3H]nisoxetine from norepinephrine transporter (NET) of rat cerebral cortex				J Med Chem 48: 3852-7 (2005) Article DOI: 10.1021/jm058164j BindingDB Entry DOI: 10.7270/Q2M909FV
					More data for this Ligand-Target Pair
Transporter (Rattus norvegicus)	BDBM50046732 ((R)-3-(4-Chloro-phenyl)-8-aza-bicyclo[3.2.1]octane...) Show SMILES COC(=O)C1C2CCC(CC1c1ccc(Cl)cc1)N2 |THB:2:4:18:6.7,11:10:18:6.7| Show InChI InChI=1S/C15H18ClNO2/c1-19-15(18)14-12(8-11-6-7-13(14)17-11)9-2-4-10(16)5-3-9/h2-5,11-14,17H,6-8H2,1H3	Reactome pathway KEGG UniProtKB/TrEMBL GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	3.10	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Research Triangle Institute Curated by ChEMBL					Assay Description Inhibition of 0.5 nM [3H]nisoxetine binding to Norepinephrine transporter				Bioorg Med Chem Lett 10: 2445-7 (2001) BindingDB Entry DOI: 10.7270/Q2474BCV
					More data for this Ligand-Target Pair
Transporter (Rattus norvegicus)	BDBM50046732 ((R)-3-(4-Chloro-phenyl)-8-aza-bicyclo[3.2.1]octane...) Show SMILES COC(=O)C1C2CCC(CC1c1ccc(Cl)cc1)N2 |THB:2:4:18:6.7,11:10:18:6.7| Show InChI InChI=1S/C15H18ClNO2/c1-19-15(18)14-12(8-11-6-7-13(14)17-11)9-2-4-10(16)5-3-9/h2-5,11-14,17H,6-8H2,1H3	Reactome pathway KEGG UniProtKB/TrEMBL GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	3.28	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Research Triangle Institute Curated by ChEMBL					Assay Description Displacement of [3H]nisoxetine from norepinephrine transporter (NET) of rat cerebral cortex				J Med Chem 48: 3852-7 (2005) Article DOI: 10.1021/jm058164j BindingDB Entry DOI: 10.7270/Q2M909FV
					More data for this Ligand-Target Pair
Transporter (Rattus norvegicus)	BDBM50046732 ((R)-3-(4-Chloro-phenyl)-8-aza-bicyclo[3.2.1]octane...) Show SMILES COC(=O)C1C2CCC(CC1c1ccc(Cl)cc1)N2 |THB:2:4:18:6.7,11:10:18:6.7| Show InChI InChI=1S/C15H18ClNO2/c1-19-15(18)14-12(8-11-6-7-13(14)17-11)9-2-4-10(16)5-3-9/h2-5,11-14,17H,6-8H2,1H3	Reactome pathway KEGG UniProtKB/TrEMBL GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	3.30	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Research Triangle Institute Curated by ChEMBL					Assay Description Inhibition of 0.5 nM [3H]nisoxetine binding to Norepinephrine transporter				Bioorg Med Chem Lett 10: 2445-7 (2001) BindingDB Entry DOI: 10.7270/Q2474BCV
					More data for this Ligand-Target Pair
Sodium-dependent serotonin transporter (Rattus norvegicus (rat))	BDBM50035738 ((R)-3-(4-Chloro-phenyl)-8-methyl-8-aza-bicyclo[3.2...) Show SMILES COC(=O)C1C2CCC(CC1c1ccc(Cl)cc1)N2C |TLB:11:10:18:6.7,THB:2:4:18:6.7| Show InChI InChI=1S/C16H20ClNO2/c1-18-12-7-8-14(18)15(16(19)20-2)13(9-12)10-3-5-11(17)6-4-10/h3-6,12-15H,7-9H2,1-2H3	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Research Triangle Institute Curated by ChEMBL					Assay Description Displacement of [3H]paroxetine from serotonin transporter (5-HT) of rat cerebral cortex				J Med Chem 48: 3852-7 (2005) Article DOI: 10.1021/jm058164j BindingDB Entry DOI: 10.7270/Q2M909FV
					More data for this Ligand-Target Pair
Sodium-dependent serotonin transporter (Rattus norvegicus (rat))	BDBM50035738 ((R)-3-(4-Chloro-phenyl)-8-methyl-8-aza-bicyclo[3.2...) Show SMILES COC(=O)C1C2CCC(CC1c1ccc(Cl)cc1)N2C |TLB:11:10:18:6.7,THB:2:4:18:6.7| Show InChI InChI=1S/C16H20ClNO2/c1-18-12-7-8-14(18)15(16(19)20-2)13(9-12)10-3-5-11(17)6-4-10/h3-6,12-15H,7-9H2,1-2H3	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Research Triangle Institute Curated by ChEMBL					Assay Description Displacement of [3H]paroxetine from serotonin transporter (5-HT) of rat cerebral cortex				J Med Chem 48: 3852-7 (2005) Article DOI: 10.1021/jm058164j BindingDB Entry DOI: 10.7270/Q2M909FV
					More data for this Ligand-Target Pair
Transporter (Rattus norvegicus)	BDBM50168046 (3-(3-Fluoro-phenyl)-8-aza-bicyclo[3.2.1]octane-2-c...) Show SMILES COC(=O)C1C2CCC(CC1c1cccc(F)c1)N2 |THB:2:4:18:6.7| Show InChI InChI=1S/C15H18FNO2/c1-19-15(18)14-12(8-11-5-6-13(14)17-11)9-3-2-4-10(16)7-9/h2-4,7,11-14,17H,5-6,8H2,1H3	Reactome pathway KEGG UniProtKB/TrEMBL GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Research Triangle Institute Curated by ChEMBL					Assay Description Displacement of [3H]nisoxetine from norepinephrine transporter (NET) of rat cerebral cortex				J Med Chem 48: 3852-7 (2005) Article DOI: 10.1021/jm058164j BindingDB Entry DOI: 10.7270/Q2M909FV
					More data for this Ligand-Target Pair
Transporter (Rattus norvegicus)	BDBM50093781 (3-p-Tolyl-8-aza-bicyclo[3.2.1]octane | 3-p-Tolyl-8...) Show SMILES COC(=O)C1C2CCC(CC1c1ccc(C)cc1)N2 |THB:2:4:18:6.7,11:10:18:6.7| Show InChI InChI=1S/C16H21NO2/c1-10-3-5-11(6-4-10)13-9-12-7-8-14(17-12)15(13)16(18)19-2/h3-6,12-15,17H,7-9H2,1-2H3	Reactome pathway KEGG UniProtKB/TrEMBL GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	4.40	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Research Triangle Institute Curated by ChEMBL					Assay Description Displacement of [3H]nisoxetine from norepinephrine transporter (NET) of rat cerebral cortex				J Med Chem 48: 3852-7 (2005) Article DOI: 10.1021/jm058164j BindingDB Entry DOI: 10.7270/Q2M909FV
					More data for this Ligand-Target Pair
Transporter (Rattus norvegicus)	BDBM50093781 (3-p-Tolyl-8-aza-bicyclo[3.2.1]octane | 3-p-Tolyl-8...) Show SMILES COC(=O)C1C2CCC(CC1c1ccc(C)cc1)N2 |THB:2:4:18:6.7,11:10:18:6.7| Show InChI InChI=1S/C16H21NO2/c1-10-3-5-11(6-4-10)13-9-12-7-8-14(17-12)15(13)16(18)19-2/h3-6,12-15,17H,7-9H2,1-2H3	Reactome pathway KEGG UniProtKB/TrEMBL GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	4.40	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Research Triangle Institute Curated by ChEMBL					Assay Description Displacement of [3H]nisoxetine from norepinephrine transporter (NET) of rat cerebral cortex				J Med Chem 48: 3852-7 (2005) Article DOI: 10.1021/jm058164j BindingDB Entry DOI: 10.7270/Q2M909FV
					More data for this Ligand-Target Pair
Sodium-dependent serotonin transporter (Rattus norvegicus (rat))	BDBM50046732 ((R)-3-(4-Chloro-phenyl)-8-aza-bicyclo[3.2.1]octane...) Show SMILES COC(=O)C1C2CCC(CC1c1ccc(Cl)cc1)N2 |THB:2:4:18:6.7,11:10:18:6.7| Show InChI InChI=1S/C15H18ClNO2/c1-19-15(18)14-12(8-11-6-7-13(14)17-11)9-2-4-10(16)5-3-9/h2-5,11-14,17H,6-8H2,1H3	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	4.80	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Research Triangle Institute Curated by ChEMBL					Assay Description Inhibition of 0.2 nM [3H]paroxetine binding to Serotonin transporter				Bioorg Med Chem Lett 10: 2445-7 (2001) BindingDB Entry DOI: 10.7270/Q2474BCV
					More data for this Ligand-Target Pair
Sodium-dependent serotonin transporter (Rattus norvegicus (rat))	BDBM50046732 ((R)-3-(4-Chloro-phenyl)-8-aza-bicyclo[3.2.1]octane...) Show SMILES COC(=O)C1C2CCC(CC1c1ccc(Cl)cc1)N2 |THB:2:4:18:6.7,11:10:18:6.7| Show InChI InChI=1S/C15H18ClNO2/c1-19-15(18)14-12(8-11-6-7-13(14)17-11)9-2-4-10(16)5-3-9/h2-5,11-14,17H,6-8H2,1H3	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	4.80	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Research Triangle Institute Curated by ChEMBL					Assay Description Inhibition of 0.5 nM [3H]nisoxetine binding toNorepinephrine transporter				Bioorg Med Chem Lett 10: 2445-7 (2001) BindingDB Entry DOI: 10.7270/Q2474BCV
					More data for this Ligand-Target Pair
Transporter (Rattus norvegicus)	BDBM50093781 (3-p-Tolyl-8-aza-bicyclo[3.2.1]octane | 3-p-Tolyl-8...) Show SMILES COC(=O)C1C2CCC(CC1c1ccc(C)cc1)N2 |THB:2:4:18:6.7,11:10:18:6.7| Show InChI InChI=1S/C16H21NO2/c1-10-3-5-11(6-4-10)13-9-12-7-8-14(17-12)15(13)16(18)19-2/h3-6,12-15,17H,7-9H2,1-2H3	Reactome pathway KEGG UniProtKB/TrEMBL GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	5.20	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Research Triangle Institute Curated by ChEMBL					Assay Description Inhibition of 0.5 nM [3H]nisoxetine binding to Norepinephrine transporter				Bioorg Med Chem Lett 10: 2445-7 (2001) BindingDB Entry DOI: 10.7270/Q2474BCV
					More data for this Ligand-Target Pair
Transporter (Rattus norvegicus)	BDBM50093781 (3-p-Tolyl-8-aza-bicyclo[3.2.1]octane | 3-p-Tolyl-8...) Show SMILES COC(=O)C1C2CCC(CC1c1ccc(C)cc1)N2 |THB:2:4:18:6.7,11:10:18:6.7| Show InChI InChI=1S/C16H21NO2/c1-10-3-5-11(6-4-10)13-9-12-7-8-14(17-12)15(13)16(18)19-2/h3-6,12-15,17H,7-9H2,1-2H3	Reactome pathway KEGG UniProtKB/TrEMBL GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	5.20	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Research Triangle Institute Curated by ChEMBL					Assay Description Inhibition of 0.5 nM [3H]nisoxetine binding toNorepinephrine transporter				Bioorg Med Chem Lett 10: 2445-7 (2001) BindingDB Entry DOI: 10.7270/Q2474BCV
					More data for this Ligand-Target Pair
Transporter (Rattus norvegicus)	BDBM50046737 (3-(4-Fluoro-phenyl)-8-aza-bicyclo[3.2.1]octane-2-c...) Show SMILES COC(=O)C1C2CCC(CC1c1ccc(F)cc1)N2 |THB:2:4:18:6.7,11:10:18:6.7| Show InChI InChI=1S/C15H18FNO2/c1-19-15(18)14-12(8-11-6-7-13(14)17-11)9-2-4-10(16)5-3-9/h2-5,11-14,17H,6-8H2,1H3	Reactome pathway KEGG UniProtKB/TrEMBL GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	5.90	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Research Triangle Institute Curated by ChEMBL					Assay Description Inhibition of 0.2 nM [3H]paroxetine binding to Serotonin transporter				Bioorg Med Chem Lett 10: 2445-7 (2001) BindingDB Entry DOI: 10.7270/Q2474BCV
					More data for this Ligand-Target Pair
Transporter (Rattus norvegicus)	BDBM50046737 (3-(4-Fluoro-phenyl)-8-aza-bicyclo[3.2.1]octane-2-c...) Show SMILES COC(=O)C1C2CCC(CC1c1ccc(F)cc1)N2 |THB:2:4:18:6.7,11:10:18:6.7| Show InChI InChI=1S/C15H18FNO2/c1-19-15(18)14-12(8-11-6-7-13(14)17-11)9-2-4-10(16)5-3-9/h2-5,11-14,17H,6-8H2,1H3	Reactome pathway KEGG UniProtKB/TrEMBL GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	5.90	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Research Triangle Institute Curated by ChEMBL					Assay Description Inhibition of 0.5 nM [3H]nisoxetine binding to Norepinephrine transporter				Bioorg Med Chem Lett 10: 2445-7 (2001) BindingDB Entry DOI: 10.7270/Q2474BCV
					More data for this Ligand-Target Pair
Sodium-dependent dopamine transporter (Homo sapiens (Human))	BDBM22403 (2-[(1R,2S,3S,5S)-3-(4-chlorophenyl)-8-methyl-8-aza...) Show SMILES CN1[C@H]2CC[C@@H]1[C@H]([C@H](C2)c1ccc(Cl)cc1)c1ncc(s1)-c1ccc(cc1)[N+]([O-])=O |TLB:0:1:4.3:7.8.6| Show InChI InChI=1S/C23H22ClN3O2S/c1-26-18-10-11-20(26)22(19(12-18)14-2-6-16(24)7-3-14)23-25-13-21(30-23)15-4-8-17(9-5-15)27(28)29/h2-9,13,18-20,22H,10-12H2,1H3/t18-,19+,20+,22-/m0/s1	NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	6.10	n/a	n/a	n/a	30	n/a	n/a	n/a	n/a
Research Triangle Institute					Assay Description Membranes were preincubated with drugs before the addition of [125I]RTI-55. The reaction was terminated by filtration through Wallac Filtermat A filt...				J Med Chem 50: 3686-95 (2007) Article DOI: 10.1021/jm0703035 BindingDB Entry DOI: 10.7270/Q25D8Q4T
					More data for this Ligand-Target Pair
Sodium-dependent serotonin transporter (Rattus norvegicus (rat))	BDBM50046737 (3-(4-Fluoro-phenyl)-8-aza-bicyclo[3.2.1]octane-2-c...) Show SMILES COC(=O)C1C2CCC(CC1c1ccc(F)cc1)N2 |THB:2:4:18:6.7,11:10:18:6.7| Show InChI InChI=1S/C15H18FNO2/c1-19-15(18)14-12(8-11-6-7-13(14)17-11)9-2-4-10(16)5-3-9/h2-5,11-14,17H,6-8H2,1H3	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	6.24	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Research Triangle Institute Curated by ChEMBL					Assay Description Displacement of [3H]paroxetine from serotonin transporter (5-HT) of rat cerebral cortex				J Med Chem 48: 3852-7 (2005) Article DOI: 10.1021/jm058164j BindingDB Entry DOI: 10.7270/Q2M909FV
					More data for this Ligand-Target Pair
Sodium-dependent serotonin transporter (Rattus norvegicus (rat))	BDBM50046737 (3-(4-Fluoro-phenyl)-8-aza-bicyclo[3.2.1]octane-2-c...) Show SMILES COC(=O)C1C2CCC(CC1c1ccc(F)cc1)N2 |THB:2:4:18:6.7,11:10:18:6.7| Show InChI InChI=1S/C15H18FNO2/c1-19-15(18)14-12(8-11-6-7-13(14)17-11)9-2-4-10(16)5-3-9/h2-5,11-14,17H,6-8H2,1H3	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	6.24	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Research Triangle Institute Curated by ChEMBL					Assay Description Displacement of [3H]paroxetine from serotonin transporter (5-HT) of rat cerebral cortex				J Med Chem 48: 3852-7 (2005) Article DOI: 10.1021/jm058164j BindingDB Entry DOI: 10.7270/Q2M909FV
					More data for this Ligand-Target Pair
Sodium-dependent dopamine transporter (Homo sapiens (Human))	BDBM22404 (2-[(1R,2S,3S,5S)-3-(4-chlorophenyl)-8-methyl-8-aza...) Show SMILES CN1[C@H]2CC[C@@H]1[C@H]([C@H](C2)c1ccc(Cl)cc1)c1ncc(s1)-c1cccc(c1)[N+]([O-])=O |TLB:0:1:4.3:7.8.6| Show InChI InChI=1S/C23H22ClN3O2S/c1-26-17-9-10-20(26)22(19(12-17)14-5-7-16(24)8-6-14)23-25-13-21(30-23)15-3-2-4-18(11-15)27(28)29/h2-8,11,13,17,19-20,22H,9-10,12H2,1H3/t17-,19+,20+,22-/m0/s1	NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	7.70	n/a	n/a	n/a	45	n/a	n/a	n/a	n/a
Research Triangle Institute					Assay Description Membranes were preincubated with drugs before the addition of [125I]RTI-55. The reaction was terminated by filtration through Wallac Filtermat A filt...				J Med Chem 50: 3686-95 (2007) Article DOI: 10.1021/jm0703035 BindingDB Entry DOI: 10.7270/Q25D8Q4T
					More data for this Ligand-Target Pair
Sodium-dependent serotonin transporter (Rattus norvegicus (rat))	BDBM50046737 (3-(4-Fluoro-phenyl)-8-aza-bicyclo[3.2.1]octane-2-c...) Show SMILES COC(=O)C1C2CCC(CC1c1ccc(F)cc1)N2 |THB:2:4:18:6.7,11:10:18:6.7| Show InChI InChI=1S/C15H18FNO2/c1-19-15(18)14-12(8-11-6-7-13(14)17-11)9-2-4-10(16)5-3-9/h2-5,11-14,17H,6-8H2,1H3	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	8.40	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Research Triangle Institute Curated by ChEMBL					Assay Description Inhibition of 0.2 nM [3H]paroxetine binding to Serotonin transporter				Bioorg Med Chem Lett 10: 2445-7 (2001) BindingDB Entry DOI: 10.7270/Q2474BCV
					More data for this Ligand-Target Pair
Sodium-dependent serotonin transporter (Rattus norvegicus (rat))	BDBM50046737 (3-(4-Fluoro-phenyl)-8-aza-bicyclo[3.2.1]octane-2-c...) Show SMILES COC(=O)C1C2CCC(CC1c1ccc(F)cc1)N2 |THB:2:4:18:6.7,11:10:18:6.7| Show InChI InChI=1S/C15H18FNO2/c1-19-15(18)14-12(8-11-6-7-13(14)17-11)9-2-4-10(16)5-3-9/h2-5,11-14,17H,6-8H2,1H3	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	8.40	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Research Triangle Institute Curated by ChEMBL					Assay Description Inhibition of 0.2 nM [3H]paroxetine binding to Serotonin transporter				Bioorg Med Chem Lett 10: 2445-7 (2001) BindingDB Entry DOI: 10.7270/Q2474BCV
					More data for this Ligand-Target Pair
Sodium-dependent dopamine transporter (Homo sapiens (Human))	BDBM22405 (2-[(1R,2S,3S,5S)-3-(4-chlorophenyl)-8-methyl-8-aza...) Show SMILES COc1ccc(cc1)-c1cnc(s1)[C@@H]1[C@H]2CC[C@@H](C[C@@H]1c1ccc(Cl)cc1)N2C |TLB:28:27:15.16:19.18.13| Show InChI InChI=1S/C24H25ClN2OS/c1-27-18-9-12-21(27)23(20(13-18)15-3-7-17(25)8-4-15)24-26-14-22(29-24)16-5-10-19(28-2)11-6-16/h3-8,10-11,14,18,20-21,23H,9,12-13H2,1-2H3/t18-,20+,21+,23-/m0/s1	NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	8.60	n/a	n/a	n/a	38	n/a	n/a	n/a	n/a
Research Triangle Institute					Assay Description Membranes were preincubated with drugs before the addition of [125I]RTI-55. The reaction was terminated by filtration through Wallac Filtermat A filt...				J Med Chem 50: 3686-95 (2007) Article DOI: 10.1021/jm0703035 BindingDB Entry DOI: 10.7270/Q25D8Q4T
					More data for this Ligand-Target Pair
Transporter (Rattus norvegicus)	BDBM50046737 (3-(4-Fluoro-phenyl)-8-aza-bicyclo[3.2.1]octane-2-c...) Show SMILES COC(=O)C1C2CCC(CC1c1ccc(F)cc1)N2 |THB:2:4:18:6.7,11:10:18:6.7| Show InChI InChI=1S/C15H18FNO2/c1-19-15(18)14-12(8-11-6-7-13(14)17-11)9-2-4-10(16)5-3-9/h2-5,11-14,17H,6-8H2,1H3	Reactome pathway KEGG UniProtKB/TrEMBL GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	11.3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Research Triangle Institute Curated by ChEMBL					Assay Description Displacement of [3H]nisoxetine from norepinephrine transporter (NET) of rat cerebral cortex				J Med Chem 48: 3852-7 (2005) Article DOI: 10.1021/jm058164j BindingDB Entry DOI: 10.7270/Q2M909FV
					More data for this Ligand-Target Pair
Transporter (Rattus norvegicus)	BDBM50046737 (3-(4-Fluoro-phenyl)-8-aza-bicyclo[3.2.1]octane-2-c...) Show SMILES COC(=O)C1C2CCC(CC1c1ccc(F)cc1)N2 |THB:2:4:18:6.7,11:10:18:6.7| Show InChI InChI=1S/C15H18FNO2/c1-19-15(18)14-12(8-11-6-7-13(14)17-11)9-2-4-10(16)5-3-9/h2-5,11-14,17H,6-8H2,1H3	Reactome pathway KEGG UniProtKB/TrEMBL GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	11.3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Research Triangle Institute Curated by ChEMBL					Assay Description Displacement of [3H]nisoxetine from norepinephrine transporter (NET) of rat cerebral cortex				J Med Chem 48: 3852-7 (2005) Article DOI: 10.1021/jm058164j BindingDB Entry DOI: 10.7270/Q2M909FV
					More data for this Ligand-Target Pair
Sodium-dependent serotonin transporter (Rattus norvegicus (rat))	BDBM50093781 (3-p-Tolyl-8-aza-bicyclo[3.2.1]octane | 3-p-Tolyl-8...) Show SMILES COC(=O)C1C2CCC(CC1c1ccc(C)cc1)N2 |THB:2:4:18:6.7,11:10:18:6.7| Show InChI InChI=1S/C16H21NO2/c1-10-3-5-11(6-4-10)13-9-12-7-8-14(17-12)15(13)16(18)19-2/h3-6,12-15,17H,7-9H2,1-2H3	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	12	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Research Triangle Institute Curated by ChEMBL					Assay Description Displacement of [3H]paroxetine from serotonin transporter (5-HT) of rat cerebral cortex				J Med Chem 48: 3852-7 (2005) Article DOI: 10.1021/jm058164j BindingDB Entry DOI: 10.7270/Q2M909FV
					More data for this Ligand-Target Pair
Sodium-dependent serotonin transporter (Rattus norvegicus (rat))	BDBM50093781 (3-p-Tolyl-8-aza-bicyclo[3.2.1]octane | 3-p-Tolyl-8...) Show SMILES COC(=O)C1C2CCC(CC1c1ccc(C)cc1)N2 |THB:2:4:18:6.7,11:10:18:6.7| Show InChI InChI=1S/C16H21NO2/c1-10-3-5-11(6-4-10)13-9-12-7-8-14(17-12)15(13)16(18)19-2/h3-6,12-15,17H,7-9H2,1-2H3	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	12	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Research Triangle Institute Curated by ChEMBL					Assay Description Displacement of [3H]paroxetine from serotonin transporter (5-HT) of rat cerebral cortex				J Med Chem 48: 3852-7 (2005) Article DOI: 10.1021/jm058164j BindingDB Entry DOI: 10.7270/Q2M909FV
					More data for this Ligand-Target Pair
Sodium-dependent dopamine transporter (Homo sapiens (Human))	BDBM22399 (2-[(1R,2S,3S,5S)-3-(4-chlorophenyl)-8-methyl-8-aza...) Show SMILES CN1[C@H]2CC[C@@H]1[C@H]([C@H](C2)c1ccc(Cl)cc1)c1ncc(s1)-c1ccc(F)cc1 |TLB:0:1:4.3:7.8.6| Show InChI InChI=1S/C23H22ClFN2S/c1-27-18-10-11-20(27)22(19(12-18)14-2-6-16(24)7-3-14)23-26-13-21(28-23)15-4-8-17(25)9-5-15/h2-9,13,18-20,22H,10-12H2,1H3/t18-,19+,20+,22-/m0/s1	NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	12	n/a	n/a	n/a	30	n/a	n/a	n/a	n/a
Research Triangle Institute					Assay Description Membranes were preincubated with drugs before the addition of [125I]RTI-55. The reaction was terminated by filtration through Wallac Filtermat A filt...				J Med Chem 50: 3686-95 (2007) Article DOI: 10.1021/jm0703035 BindingDB Entry DOI: 10.7270/Q25D8Q4T
					More data for this Ligand-Target Pair
Sodium-dependent dopamine transporter (Homo sapiens (Human))	BDBM22410 (5-(3-bromophenyl)-2-[(1R,2S,3S,5S)-8-methyl-3-(4-m...) Show SMILES CN1[C@H]2CC[C@@H]1[C@H]([C@H](C2)c1ccc(C)cc1)c1ncc(s1)-c1cccc(Br)c1 |TLB:0:1:4.3:7.8.6| Show InChI InChI=1S/C24H25BrN2S/c1-15-6-8-16(9-7-15)20-13-19-10-11-21(27(19)2)23(20)24-26-14-22(28-24)17-4-3-5-18(25)12-17/h3-9,12,14,19-21,23H,10-11,13H2,1-2H3/t19-,20+,21+,23-/m0/s1	NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	12	n/a	n/a	n/a	98	n/a	n/a	n/a	n/a
Research Triangle Institute					Assay Description Membranes were preincubated with drugs before the addition of [125I]RTI-55. The reaction was terminated by filtration through Wallac Filtermat A filt...				J Med Chem 50: 3686-95 (2007) Article DOI: 10.1021/jm0703035 BindingDB Entry DOI: 10.7270/Q25D8Q4T
					More data for this Ligand-Target Pair
Sodium-dependent serotonin transporter (Rattus norvegicus (rat))	BDBM50168044 (3-(3,5-Difluoro-phenyl)-8-aza-bicyclo[3.2.1]octane...) Show SMILES COC(=O)C1C2CCC(CC1c1cc(F)cc(F)c1)N2 |THB:2:4:19:6.7| Show InChI InChI=1S/C15H17F2NO2/c1-20-15(19)14-12(7-11-2-3-13(14)18-11)8-4-9(16)6-10(17)5-8/h4-6,11-14,18H,2-3,7H2,1H3	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	13.7	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Research Triangle Institute Curated by ChEMBL					Assay Description Displacement of [3H]paroxetine from serotonin transporter (5-HT) of rat cerebral cortex				J Med Chem 48: 3852-7 (2005) Article DOI: 10.1021/jm058164j BindingDB Entry DOI: 10.7270/Q2M909FV
					More data for this Ligand-Target Pair
Sodium-dependent dopamine transporter (Homo sapiens (Human))	BDBM22412 (2-[(1R,2S,3S,5S)-8-methyl-3-(4-methylphenyl)-8-aza...) Show SMILES CN1[C@H]2CC[C@@H]1[C@H]([C@H](C2)c1ccc(C)cc1)c1ncc(s1)-c1cccc(c1)[N+]([O-])=O |TLB:0:1:4.3:7.8.6| Show InChI InChI=1S/C24H25N3O2S/c1-15-6-8-16(9-7-15)20-13-18-10-11-21(26(18)2)23(20)24-25-14-22(30-24)17-4-3-5-19(12-17)27(28)29/h3-9,12,14,18,20-21,23H,10-11,13H2,1-2H3/t18-,20+,21+,23-/m0/s1	NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	14	n/a	n/a	n/a	23	n/a	n/a	n/a	n/a
Research Triangle Institute					Assay Description Membranes were preincubated with drugs before the addition of [125I]RTI-55. The reaction was terminated by filtration through Wallac Filtermat A filt...				J Med Chem 50: 3686-95 (2007) Article DOI: 10.1021/jm0703035 BindingDB Entry DOI: 10.7270/Q25D8Q4T
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2B (Homo sapiens (Human))	BDBM86233 (CAS_66104-22-1 | NSC_47812 | PERGOLIDE) Show SMILES CCCN1CC(CSC)CC2C1Cc1c[nH]c3cccc2c13 Show InChI InChI=1S/C19H26N2S/c1-3-7-21-11-13(12-22-2)8-16-15-5-4-6-17-19(15)14(10-20-17)9-18(16)21/h4-6,10,13,16,18,20H,3,7-9,11-12H2,1-2H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	Article PubMed	14	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Case Western Reserve University Curated by PDSP Ki Database									Mol Pharmacol 63: 1223-9 (2003) Article DOI: 10.1124/mol.63.6.1223 BindingDB Entry DOI: 10.7270/Q2FN14SJ
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2B (Homo sapiens (Human))	BDBM86236 (CAS_15897 | NSC_15897 | Norfenfluramine) Show SMILES CC(N)Cc1cccc(c1)C(F)(F)F Show InChI InChI=1S/C10H12F3N/c1-7(14)5-8-3-2-4-9(6-8)10(11,12)13/h2-4,6-7H,5,14H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Patents Similars	Article PubMed	15	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Case Western Reserve University Curated by PDSP Ki Database									Mol Pharmacol 63: 1223-9 (2003) Article DOI: 10.1124/mol.63.6.1223 BindingDB Entry DOI: 10.7270/Q2FN14SJ
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2B (Homo sapiens (Human))	BDBM86235 (CAS_3066 | DHE | NSC_3066) Show SMILES CN1CC(CC2C1Cc1c[nH]c3cccc2c13)C(=O)NC1(C)OC2(O)C3CCCN3C(=O)C(Cc3ccccc3)N2C1=O Show InChI InChI=1S/C33H37N5O5/c1-32(35-29(39)21-15-23-22-10-6-11-24-28(22)20(17-34-24)16-25(23)36(2)18-21)31(41)38-26(14-19-8-4-3-5-9-19)30(40)37-13-7-12-27(37)33(38,42)43-32/h3-6,8-11,17,21,23,25-27,34,42H,7,12-16,18H2,1-2H3,(H,35,39)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid PDB UniChem Similars	Article PubMed	15.2	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Case Western Reserve University Curated by PDSP Ki Database									Mol Pharmacol 63: 1223-9 (2003) Article DOI: 10.1124/mol.63.6.1223 BindingDB Entry DOI: 10.7270/Q2FN14SJ
					More data for this Ligand-Target Pair
Sodium-dependent serotonin transporter (Rattus norvegicus (rat))	BDBM50168042 (3-(4-Fluoro-3-methyl-phenyl)-8-aza-bicyclo[3.2.1]o...) Show SMILES COC(=O)C1C2CCC(CC1c1ccc(F)c(C)c1)N2 |THB:2:4:19:6.7| Show InChI InChI=1S/C16H20FNO2/c1-9-7-10(3-5-13(9)17)12-8-11-4-6-14(18-11)15(12)16(19)20-2/h3,5,7,11-12,14-15,18H,4,6,8H2,1-2H3	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	17.1	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Research Triangle Institute Curated by ChEMBL					Assay Description Displacement of [3H]paroxetine from serotonin transporter (5-HT) of rat cerebral cortex				J Med Chem 48: 3852-7 (2005) Article DOI: 10.1021/jm058164j BindingDB Entry DOI: 10.7270/Q2M909FV
					More data for this Ligand-Target Pair
Sodium-dependent dopamine transporter (Homo sapiens (Human))	BDBM22398 (2-[(1R,2S,3S,5S)-3-(4-chlorophenyl)-8-methyl-8-aza...) Show SMILES CN1[C@H]2CC[C@@H]1[C@H]([C@H](C2)c1ccc(Cl)cc1)c1ncc(s1)-c1ccccc1 |TLB:0:1:4.3:7.8.6| Show InChI InChI=1S/C23H23ClN2S/c1-26-18-11-12-20(26)22(19(13-18)15-7-9-17(24)10-8-15)23-25-14-21(27-23)16-5-3-2-4-6-16/h2-10,14,18-20,22H,11-13H2,1H3/t18-,19+,20+,22-/m0/s1	NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	18	n/a	n/a	n/a	158	n/a	n/a	n/a	n/a
Research Triangle Institute					Assay Description Membranes were preincubated with drugs before the addition of [125I]RTI-55. The reaction was terminated by filtration through Wallac Filtermat A filt...				J Med Chem 50: 3686-95 (2007) Article DOI: 10.1021/jm0703035 BindingDB Entry DOI: 10.7270/Q25D8Q4T
					More data for this Ligand-Target Pair
Sodium-dependent noradrenaline transporter (Homo sapiens (Human))	BDBM50191341 (5,6,7,8,10,14a,15,16,17,18,19,19a-dodecahydro-20-m...) Show SMILES CN1C2CCC1C1COC(=O)CCCCCC(=O)Nc3ccc(cc3)C1C2 |TLB:7:6:1:3.4,THB:22:25:1:3.4| Show InChI InChI=1S/C22H30N2O3/c1-24-17-11-12-20(24)19-14-27-22(26)6-4-2-3-5-21(25)23-16-9-7-15(8-10-16)18(19)13-17/h7-10,17-20H,2-6,11-14H2,1H3,(H,23,25)	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	20	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Research Triangle Institute Curated by ChEMBL					Assay Description Displacement of [3H]nisoxetine from human NET				J Med Chem 49: 4589-94 (2006) Article DOI: 10.1021/jm060287w BindingDB Entry DOI: 10.7270/Q28053DM
					More data for this Ligand-Target Pair
Transporter (Rattus norvegicus)	BDBM50035738 ((R)-3-(4-Chloro-phenyl)-8-methyl-8-aza-bicyclo[3.2...) Show SMILES COC(=O)C1C2CCC(CC1c1ccc(Cl)cc1)N2C |TLB:11:10:18:6.7,THB:2:4:18:6.7| Show InChI InChI=1S/C16H20ClNO2/c1-18-12-7-8-14(18)15(16(19)20-2)13(9-12)10-3-5-11(17)6-4-10/h3-6,12-15H,7-9H2,1-2H3	Reactome pathway KEGG UniProtKB/TrEMBL GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	22	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Research Triangle Institute Curated by ChEMBL					Assay Description Displacement of [3H]nisoxetine from norepinephrine transporter (NET) of rat cerebral cortex				J Med Chem 48: 3852-7 (2005) Article DOI: 10.1021/jm058164j BindingDB Entry DOI: 10.7270/Q2M909FV
					More data for this Ligand-Target Pair
Sodium-dependent serotonin transporter (Rattus norvegicus (rat))	BDBM50035729 (8-Methyl-3-p-tolyl-8-aza-bicyclo[3.2.1]octane | 8-...) Show SMILES COC(=O)C1C2CCC(CC1c1ccc(C)cc1)N2C |THB:2:4:18:6.7,11:10:18:6.7| Show InChI InChI=1S/C17H23NO2/c1-11-4-6-12(7-5-11)14-10-13-8-9-15(18(13)2)16(14)17(19)20-3/h4-7,13-16H,8-10H2,1-3H3	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	22	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Research Triangle Institute Curated by ChEMBL					Assay Description Displacement of [3H]paroxetine from serotonin transporter (5-HT) of rat cerebral cortex				J Med Chem 48: 3852-7 (2005) Article DOI: 10.1021/jm058164j BindingDB Entry DOI: 10.7270/Q2M909FV
					More data for this Ligand-Target Pair
Transporter (Rattus norvegicus)	BDBM50035738 ((R)-3-(4-Chloro-phenyl)-8-methyl-8-aza-bicyclo[3.2...) Show SMILES COC(=O)C1C2CCC(CC1c1ccc(Cl)cc1)N2C |TLB:11:10:18:6.7,THB:2:4:18:6.7| Show InChI InChI=1S/C16H20ClNO2/c1-18-12-7-8-14(18)15(16(19)20-2)13(9-12)10-3-5-11(17)6-4-10/h3-6,12-15H,7-9H2,1-2H3	Reactome pathway KEGG UniProtKB/TrEMBL GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	22	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Research Triangle Institute Curated by ChEMBL					Assay Description Displacement of [3H]nisoxetine from norepinephrine transporter (NET) of rat cerebral cortex				J Med Chem 48: 3852-7 (2005) Article DOI: 10.1021/jm058164j BindingDB Entry DOI: 10.7270/Q2M909FV
					More data for this Ligand-Target Pair
Sodium-dependent serotonin transporter (Rattus norvegicus (rat))	BDBM50035729 (8-Methyl-3-p-tolyl-8-aza-bicyclo[3.2.1]octane | 8-...) Show SMILES COC(=O)C1C2CCC(CC1c1ccc(C)cc1)N2C |THB:2:4:18:6.7,11:10:18:6.7| Show InChI InChI=1S/C17H23NO2/c1-11-4-6-12(7-5-11)14-10-13-8-9-15(18(13)2)16(14)17(19)20-3/h4-7,13-16H,8-10H2,1-3H3	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	22	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Research Triangle Institute Curated by ChEMBL					Assay Description Displacement of [3H]paroxetine from serotonin transporter (5-HT) of rat cerebral cortex				J Med Chem 48: 3852-7 (2005) Article DOI: 10.1021/jm058164j BindingDB Entry DOI: 10.7270/Q2M909FV
					More data for this Ligand-Target Pair

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