Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Protein-S-isoprenylcysteine O-methyltransferase (Homo sapiens (Human)) | BDBM50183409 (CHEMBL3822531) | KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem | PubMed | 1.10E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Icahn School of Medicine at Mount Sinai Curated by ChEMBL | Assay Description Competitive inhibition of human isoprenylcysteine carboxyl methyltransferase expressed in yeast His10myc3N-Icmt membranes using increasing AFC substr... | Medchemcomm 7: 1016-1021 (2016) BindingDB Entry DOI: 10.7270/Q2C82C8P | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Protein-S-isoprenylcysteine O-methyltransferase (Homo sapiens (Human)) | BDBM50183409 (CHEMBL3822531) | KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem | PubMed | 2.90E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Icahn School of Medicine at Mount Sinai Curated by ChEMBL | Assay Description Non-competitive inhibition of human isoprenylcysteine carboxyl methyltransferase expressed in yeast His10myc3N-Icmt membranes with increasing [14C]-S... | Medchemcomm 7: 1016-1021 (2016) BindingDB Entry DOI: 10.7270/Q2C82C8P | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Protein-S-isoprenylcysteine O-methyltransferase (Homo sapiens (Human)) | BDBM50384449 (CHEMBL2035530) | KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 400 | n/a | n/a | n/a | n/a | n/a | n/a |
Icahn School of Medicine at Mount Sinai Curated by ChEMBL | Assay Description Inhibition of human isoprenylcysteine carboxyl methyltransferase expressed in yeast His10myc3N-Icmt membranes using AFC substrate and [14C]-SAM and i... | Medchemcomm 7: 1016-1021 (2016) BindingDB Entry DOI: 10.7270/Q2C82C8P | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Protein-S-isoprenylcysteine O-methyltransferase (Homo sapiens (Human)) | BDBM50183409 (CHEMBL3822531) | KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem | PubMed | n/a | n/a | 1.50E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Icahn School of Medicine at Mount Sinai Curated by ChEMBL | Assay Description Inhibition of human isoprenylcysteine carboxyl methyltransferase expressed in yeast His10myc3N-Icmt membranes using AFC substrate and [14C]-SAM and i... | Medchemcomm 7: 1016-1021 (2016) BindingDB Entry DOI: 10.7270/Q2C82C8P | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Protein-S-isoprenylcysteine O-methyltransferase (Homo sapiens (Human)) | BDBM50183444 (CHEMBL3823651) | KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 2.20E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Icahn School of Medicine at Mount Sinai Curated by ChEMBL | Assay Description Inhibition of human isoprenylcysteine carboxyl methyltransferase expressed in yeast His10myc3N-Icmt membranes using AFC substrate and [14C]-SAM and i... | Medchemcomm 7: 1016-1021 (2016) BindingDB Entry DOI: 10.7270/Q2C82C8P | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Broad substrate specificity ATP-binding cassette transporter ABCG2 (Homo sapiens (Human)) | BDBM50260355 (CHEMBL2063071) | PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 4.30E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Purdue University Curated by ChEMBL | Assay Description Inhibition of human ABCG2 expressed in Sf9 cell membranes assessed as reduction in [125I]-IAAP binding incubated for 20 mins under UV light irradiati... | Bioorg Med Chem 25: 5128-5132 (2017) Article DOI: 10.1016/j.bmc.2017.07.001 BindingDB Entry DOI: 10.7270/Q2DB84BZ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Protein-S-isoprenylcysteine O-methyltransferase (Homo sapiens (Human)) | BDBM50183445 (CHEMBL3822621) | KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 7.70E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Icahn School of Medicine at Mount Sinai Curated by ChEMBL | Assay Description Inhibition of human isoprenylcysteine carboxyl methyltransferase expressed in yeast His10myc3N-Icmt membranes using AFC substrate and [14C]-SAM and i... | Medchemcomm 7: 1016-1021 (2016) BindingDB Entry DOI: 10.7270/Q2C82C8P | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
ATP-dependent translocase ABCB1 (Homo sapiens (Human)) | BDBM50260355 (CHEMBL2063071) | PDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 9.30E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Purdue University Curated by ChEMBL | Assay Description Inhibition of human MDR1 expressed in Sf9 cell membranes assessed as reduction in [125I]-IAAP binding incubated for 20 mins under UV light irradiatio... | Bioorg Med Chem 25: 5128-5132 (2017) Article DOI: 10.1016/j.bmc.2017.07.001 BindingDB Entry DOI: 10.7270/Q2DB84BZ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Broad substrate specificity ATP-binding cassette transporter ABCG2 (Homo sapiens (Human)) | BDBM50260355 (CHEMBL2063071) | PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 1.15E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Purdue University Curated by ChEMBL | Assay Description Inhibition of human ABCG2 expressed in Sf9 cell membranes assessed as reduction in [125I]-IAAP binding incubated for 20 mins under UV light irradiati... | Bioorg Med Chem 25: 5128-5132 (2017) Article DOI: 10.1016/j.bmc.2017.07.001 BindingDB Entry DOI: 10.7270/Q2DB84BZ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Broad substrate specificity ATP-binding cassette transporter ABCG2 (Homo sapiens (Human)) | BDBM50260356 (CHEMBL2063072) | PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 1.33E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Purdue University Curated by ChEMBL | Assay Description Inhibition of human ABCG2 expressed in Sf9 cell membranes assessed as reduction in [125I]-IAAP binding incubated for 20 mins under UV light irradiati... | Bioorg Med Chem 25: 5128-5132 (2017) Article DOI: 10.1016/j.bmc.2017.07.001 BindingDB Entry DOI: 10.7270/Q2DB84BZ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Protein-S-isoprenylcysteine O-methyltransferase (Homo sapiens (Human)) | BDBM50183447 (CHEMBL3823076) | KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 1.40E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Icahn School of Medicine at Mount Sinai Curated by ChEMBL | Assay Description Inhibition of human isoprenylcysteine carboxyl methyltransferase expressed in yeast His10myc3N-Icmt membranes using AFC substrate and [14C]-SAM and i... | Medchemcomm 7: 1016-1021 (2016) BindingDB Entry DOI: 10.7270/Q2C82C8P | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Protein-S-isoprenylcysteine O-methyltransferase (Homo sapiens (Human)) | BDBM50183446 (CHEMBL3822563) | KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 1.80E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Icahn School of Medicine at Mount Sinai Curated by ChEMBL | Assay Description Inhibition of human isoprenylcysteine carboxyl methyltransferase expressed in yeast His10myc3N-Icmt membranes using AFC substrate and [14C]-SAM and i... | Medchemcomm 7: 1016-1021 (2016) BindingDB Entry DOI: 10.7270/Q2C82C8P | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Broad substrate specificity ATP-binding cassette transporter ABCG2 (Homo sapiens (Human)) | BDBM50260357 (CHEMBL2063070) | PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 2.82E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Purdue University Curated by ChEMBL | Assay Description Inhibition of human ABCG2 expressed in Sf9 cell membranes assessed as reduction in [125I]-IAAP binding incubated for 20 mins under UV light irradiati... | Bioorg Med Chem 25: 5128-5132 (2017) Article DOI: 10.1016/j.bmc.2017.07.001 BindingDB Entry DOI: 10.7270/Q2DB84BZ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Protein-S-isoprenylcysteine O-methyltransferase (Homo sapiens (Human)) | BDBM50183442 (CHEMBL3823998) | KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | >5.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Icahn School of Medicine at Mount Sinai Curated by ChEMBL | Assay Description Inhibition of human isoprenylcysteine carboxyl methyltransferase expressed in yeast His10myc3N-Icmt membranes using AFC substrate and [14C]-SAM and i... | Medchemcomm 7: 1016-1021 (2016) BindingDB Entry DOI: 10.7270/Q2C82C8P | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Protein-S-isoprenylcysteine O-methyltransferase (Homo sapiens (Human)) | BDBM50183441 (CHEMBL3823782) | KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | >5.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Icahn School of Medicine at Mount Sinai Curated by ChEMBL | Assay Description Inhibition of human isoprenylcysteine carboxyl methyltransferase expressed in yeast His10myc3N-Icmt membranes using AFC substrate and [14C]-SAM and i... | Medchemcomm 7: 1016-1021 (2016) BindingDB Entry DOI: 10.7270/Q2C82C8P | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Protein-S-isoprenylcysteine O-methyltransferase (Homo sapiens (Human)) | BDBM50183440 (CHEMBL3823382) | KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | >5.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Icahn School of Medicine at Mount Sinai Curated by ChEMBL | Assay Description Inhibition of human isoprenylcysteine carboxyl methyltransferase expressed in yeast His10myc3N-Icmt membranes using AFC substrate and [14C]-SAM and i... | Medchemcomm 7: 1016-1021 (2016) BindingDB Entry DOI: 10.7270/Q2C82C8P | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Protein-S-isoprenylcysteine O-methyltransferase (Homo sapiens (Human)) | BDBM50183412 (CHEMBL3822723) | KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem | PubMed | n/a | n/a | >5.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Icahn School of Medicine at Mount Sinai Curated by ChEMBL | Assay Description Inhibition of human isoprenylcysteine carboxyl methyltransferase expressed in yeast His10myc3N-Icmt membranes using AFC substrate and [14C]-SAM and i... | Medchemcomm 7: 1016-1021 (2016) BindingDB Entry DOI: 10.7270/Q2C82C8P | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Protein-S-isoprenylcysteine O-methyltransferase (Homo sapiens (Human)) | BDBM50183411 (CHEMBL3824039) | KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | PubMed | n/a | n/a | >5.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Icahn School of Medicine at Mount Sinai Curated by ChEMBL | Assay Description Inhibition of human isoprenylcysteine carboxyl methyltransferase expressed in yeast His10myc3N-Icmt membranes using AFC substrate and [14C]-SAM and i... | Medchemcomm 7: 1016-1021 (2016) BindingDB Entry DOI: 10.7270/Q2C82C8P | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Protein-S-isoprenylcysteine O-methyltransferase (Homo sapiens (Human)) | BDBM50183410 (CHEMBL3823389) | KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem | PubMed | n/a | n/a | >5.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Icahn School of Medicine at Mount Sinai Curated by ChEMBL | Assay Description Inhibition of human isoprenylcysteine carboxyl methyltransferase expressed in yeast His10myc3N-Icmt membranes using AFC substrate and [14C]-SAM and i... | Medchemcomm 7: 1016-1021 (2016) BindingDB Entry DOI: 10.7270/Q2C82C8P | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Protein-S-isoprenylcysteine O-methyltransferase (Homo sapiens (Human)) | BDBM50183443 (CHEMBL3823479) | KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | >5.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Icahn School of Medicine at Mount Sinai Curated by ChEMBL | Assay Description Inhibition of human isoprenylcysteine carboxyl methyltransferase expressed in yeast His10myc3N-Icmt membranes using AFC substrate and [14C]-SAM and i... | Medchemcomm 7: 1016-1021 (2016) BindingDB Entry DOI: 10.7270/Q2C82C8P | |||||||||||
More data for this Ligand-Target Pair |