BindingDB PrimarySearch

Found 73 hits with Last Name = 'bora' and Initial = 'e'
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
NAD-dependent protein deacetylase sirtuin-2 (Homo sapiens (Human))	BDBM50513317 (CHEMBL4465620) Show SMILES Show InChI	PDB MMDB NCI pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	68	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Kyoto Prefectural University of Medicine Curated by ChEMBL					Assay Description Inhibition of human N-terminal His-tagged SIRT2 expressed in Escherichia coli using p53 (Gln-Pro-Lys-Lys(Ac)) (317 to 320 residues) as substrate incu...				J Med Chem 62: 5844-5862 (2019) Article DOI: 10.1021/acs.jmedchem.9b00255 BindingDB Entry DOI: 10.7270/Q2JH3QJR
Kyoto Prefectural University of Medicine Curated by ChEMBL					More data for this Ligand-Target Pair
NAD-dependent protein deacetylase sirtuin-2 (Homo sapiens (Human))	BDBM50513318 (CHEMBL4516553) Show SMILES Show InChI	PDB MMDB NCI pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	470	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Kyoto Prefectural University of Medicine Curated by ChEMBL					Assay Description Inhibition of human N-terminal His-tagged SIRT2 expressed in Escherichia coli using p53 (Gln-Pro-Lys-Lys(Ac)) (317 to 320 residues) as substrate incu...				J Med Chem 62: 5844-5862 (2019) Article DOI: 10.1021/acs.jmedchem.9b00255 BindingDB Entry DOI: 10.7270/Q2JH3QJR
Kyoto Prefectural University of Medicine Curated by ChEMBL					More data for this Ligand-Target Pair
Alpha-ketoglutarate-dependent dioxygenase FTO (Homo sapiens (Human))	BDBM50596052 (CHEMBL5196484) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem	Article PubMed	n/a	n/a	87	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details Article DOI: 10.1021/acs.jmedchem.1c01107 BindingDB Entry DOI: 10.7270/Q2QF8XWG
TBA					More data for this Ligand-Target Pair
Proto-oncogene tyrosine-protein kinase Src (Homo sapiens (Human))	BDBM50255048 (3,4-Difluoro-2-(2-fluoro-4-iodo-phenylamino)-5-[(5...) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	100	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Binding affinity to SRC (unknown origin)				Bioorg Med Chem Lett 19: 226-9 (2008) Article DOI: 10.1016/j.bmcl.2008.10.108 BindingDB Entry DOI: 10.7270/Q22F7N98
Pfizer Global Research and Development Curated by ChEMBL					More data for this Ligand-Target Pair
Lysine-specific histone demethylase 1A (Homo sapiens (Human))	BDBM50595758 (CHEMBL5207682) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	126	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details Article DOI: 10.1021/acsmedchemlett.2c00126 BindingDB Entry DOI: 10.7270/Q2BC43JF
TBA					More data for this Ligand-Target Pair
Tyrosine-protein kinase ABL1 (Homo sapiens (Human))	BDBM50255048 (3,4-Difluoro-2-(2-fluoro-4-iodo-phenylamino)-5-[(5...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	300	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Binding affinity to ABL (unknown origin)				Bioorg Med Chem Lett 19: 226-9 (2008) Article DOI: 10.1016/j.bmcl.2008.10.108 BindingDB Entry DOI: 10.7270/Q22F7N98
Pfizer Global Research and Development Curated by ChEMBL					More data for this Ligand-Target Pair
NAD-dependent protein deacetylase sirtuin-2 (Homo sapiens (Human))	BDBM50148781 (CHEMBL3770903) Show SMILES Show InChI	PDB MMDB NCI pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid PDB UniChem	PDB Article PubMed	n/a	n/a	300	n/a	n/a	n/a	n/a	n/a	n/a
Kyoto Prefectural University of Medicine Curated by ChEMBL					Assay Description Inhibition of human N-terminal His-tagged SIRT2 expressed in Escherichia coli using p53 (Gln-Pro-Lys-Lys(Ac)) (317 to 320 residues) as substrate incu...				J Med Chem 62: 5844-5862 (2019) Article DOI: 10.1021/acs.jmedchem.9b00255 BindingDB Entry DOI: 10.7270/Q2JH3QJR
Kyoto Prefectural University of Medicine Curated by ChEMBL					More data for this Ligand-Target Pair				3D Structure (crystal)
NAD-dependent protein deacetylase sirtuin-2 (Homo sapiens (Human))	BDBM50513317 (CHEMBL4465620) Show SMILES Show InChI	PDB MMDB NCI pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	310	n/a	n/a	n/a	n/a	n/a	n/a
Kyoto Prefectural University of Medicine Curated by ChEMBL					Assay Description Inhibition of human N-terminal His-tagged SIRT2 expressed in Escherichia coli using p53 (Gln-Pro-Lys-Lys(Ac)) (317 to 320 residues) as substrate incu...				J Med Chem 62: 5844-5862 (2019) Article DOI: 10.1021/acs.jmedchem.9b00255 BindingDB Entry DOI: 10.7270/Q2JH3QJR
Kyoto Prefectural University of Medicine Curated by ChEMBL					More data for this Ligand-Target Pair
NAD-dependent protein deacetylase sirtuin-2 (Homo sapiens (Human))	BDBM50513320 (CHEMBL4471909) Show SMILES Show InChI	PDB MMDB NCI pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	370	n/a	n/a	n/a	n/a	n/a	n/a
Kyoto Prefectural University of Medicine Curated by ChEMBL					Assay Description Inhibition of human N-terminal His-tagged SIRT2 expressed in Escherichia coli using p53 (Gln-Pro-Lys-Lys(Ac)) (317 to 320 residues) as substrate incu...				J Med Chem 62: 5844-5862 (2019) Article DOI: 10.1021/acs.jmedchem.9b00255 BindingDB Entry DOI: 10.7270/Q2JH3QJR
Kyoto Prefectural University of Medicine Curated by ChEMBL					More data for this Ligand-Target Pair
Lysine-specific histone demethylase 1A (Homo sapiens (Human))	BDBM50595759 (CHEMBL5175995) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	444	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details Article DOI: 10.1021/acsmedchemlett.2c00126 BindingDB Entry DOI: 10.7270/Q2BC43JF
TBA					More data for this Ligand-Target Pair
Lysine-specific histone demethylase 1A (Homo sapiens (Human))	BDBM50595760 (CHEMBL5177373) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	457	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details Article DOI: 10.1021/acsmedchemlett.2c00126 BindingDB Entry DOI: 10.7270/Q2BC43JF
TBA					More data for this Ligand-Target Pair
Tyrosine-protein kinase Lck (Homo sapiens (Human))	BDBM50255048 (3,4-Difluoro-2-(2-fluoro-4-iodo-phenylamino)-5-[(5...) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	500	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Binding affinity to LCK (unknown origin)				Bioorg Med Chem Lett 19: 226-9 (2008) Article DOI: 10.1016/j.bmcl.2008.10.108 BindingDB Entry DOI: 10.7270/Q22F7N98
Pfizer Global Research and Development Curated by ChEMBL					More data for this Ligand-Target Pair
Alpha-ketoglutarate-dependent dioxygenase FTO (Homo sapiens (Human))	BDBM50596051 (CHEMBL5183243) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem	Article PubMed	n/a	n/a	570	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details Article DOI: 10.1021/acs.jmedchem.1c01107 BindingDB Entry DOI: 10.7270/Q2QF8XWG
TBA					More data for this Ligand-Target Pair
NAD-dependent protein deacetylase sirtuin-2 (Homo sapiens (Human))	BDBM50513318 (CHEMBL4516553) Show SMILES Show InChI	PDB MMDB NCI pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	600	n/a	n/a	n/a	n/a	n/a	n/a
Kyoto Prefectural University of Medicine Curated by ChEMBL					Assay Description Inhibition of human N-terminal His-tagged SIRT2 expressed in Escherichia coli using p53 (Gln-Pro-Lys-Lys(Ac)) (317 to 320 residues) as substrate incu...				J Med Chem 62: 5844-5862 (2019) Article DOI: 10.1021/acs.jmedchem.9b00255 BindingDB Entry DOI: 10.7270/Q2JH3QJR
Kyoto Prefectural University of Medicine Curated by ChEMBL					More data for this Ligand-Target Pair
Alpha-ketoglutarate-dependent dioxygenase FTO (Homo sapiens (Human))	BDBM50596053 (CHEMBL5173876) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid PDB UniChem	PDB Article PubMed	n/a	n/a	930	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details Article DOI: 10.1021/acs.jmedchem.1c01107 BindingDB Entry DOI: 10.7270/Q2QF8XWG
TBA					More data for this Ligand-Target Pair				3D Structure (crystal)
Aurora kinase A (Homo sapiens (Human))	BDBM50255012 (5-((4-(methylsulfonyl)benzylamino)methyl)-3,4-difl...) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Binding affinity to Aurora A (unknown origin)				Bioorg Med Chem Lett 19: 226-9 (2008) Article DOI: 10.1016/j.bmcl.2008.10.108 BindingDB Entry DOI: 10.7270/Q22F7N98
Pfizer Global Research and Development Curated by ChEMBL					More data for this Ligand-Target Pair
NAD-dependent protein deacetylase sirtuin-2 (Homo sapiens (Human))	BDBM50513319 (CHEMBL4589851) Show SMILES Show InChI	PDB MMDB NCI pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.18E+3	n/a	n/a	n/a	n/a	n/a	n/a
Kyoto Prefectural University of Medicine Curated by ChEMBL					Assay Description Inhibition of human N-terminal His-tagged SIRT2 expressed in Escherichia coli using p53 (Gln-Pro-Lys-Lys(Ac)) (317 to 320 residues) as substrate incu...				J Med Chem 62: 5844-5862 (2019) Article DOI: 10.1021/acs.jmedchem.9b00255 BindingDB Entry DOI: 10.7270/Q2JH3QJR
Kyoto Prefectural University of Medicine Curated by ChEMBL					More data for this Ligand-Target Pair
Lysine-specific histone demethylase 1A (Homo sapiens (Human))	BDBM50595757 (CHEMBL5174314) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.29E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details Article DOI: 10.1021/acsmedchemlett.2c00126 BindingDB Entry DOI: 10.7270/Q2BC43JF
TBA					More data for this Ligand-Target Pair
NAD-dependent protein deacetylase sirtuin-2 (Homo sapiens (Human))	BDBM50392111 (CHEMBL2152613) Show SMILES NC(=O)c1ccccc1Nc1cccc(OCCc2ccccc2)c1 Show InChI	PDB MMDB NCI pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid PDB UniChem Similars	PDB Article PubMed	n/a	n/a	1.74E+3	n/a	n/a	n/a	n/a	n/a	n/a
Kyoto Prefectural University of Medicine Curated by ChEMBL					Assay Description Inhibition of human N-terminal His-tagged SIRT2 expressed in Escherichia coli using p53 (Gln-Pro-Lys-Lys(Ac)) (317 to 320 residues) as substrate incu...				J Med Chem 62: 5844-5862 (2019) Article DOI: 10.1021/acs.jmedchem.9b00255 BindingDB Entry DOI: 10.7270/Q2JH3QJR
Kyoto Prefectural University of Medicine Curated by ChEMBL					More data for this Ligand-Target Pair				3D Structure (crystal)
Aurora kinase A (Homo sapiens (Human))	BDBM50255013 ((S)-5-((2,4-diamino-4-oxobutanamido)methyl)-3,4-di...) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	2.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Binding affinity to Aurora A (unknown origin)				Bioorg Med Chem Lett 19: 226-9 (2008) Article DOI: 10.1016/j.bmcl.2008.10.108 BindingDB Entry DOI: 10.7270/Q22F7N98
Pfizer Global Research and Development Curated by ChEMBL					More data for this Ligand-Target Pair
Tumor necrosis factor receptor superfamily member 1A (Homo sapiens (Human))	BDBM50255012 (5-((4-(methylsulfonyl)benzylamino)methyl)-3,4-difl...) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	2.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Binding affinity to TRAK-A (unknown origin)				Bioorg Med Chem Lett 19: 226-9 (2008) Article DOI: 10.1016/j.bmcl.2008.10.108 BindingDB Entry DOI: 10.7270/Q22F7N98
Pfizer Global Research and Development Curated by ChEMBL					More data for this Ligand-Target Pair
Protein kinase C beta type (Homo sapiens (Human))	BDBM50255013 ((S)-5-((2,4-diamino-4-oxobutanamido)methyl)-3,4-di...) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	2.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Binding affinity to PKC beta2 (unknown origin)				Bioorg Med Chem Lett 19: 226-9 (2008) Article DOI: 10.1016/j.bmcl.2008.10.108 BindingDB Entry DOI: 10.7270/Q22F7N98
Pfizer Global Research and Development Curated by ChEMBL					More data for this Ligand-Target Pair
Fibroblast growth factor receptor 1 (Homo sapiens (Human))	BDBM50255048 (3,4-Difluoro-2-(2-fluoro-4-iodo-phenylamino)-5-[(5...) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	2.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Binding affinity to FGFR1 (unknown origin)				Bioorg Med Chem Lett 19: 226-9 (2008) Article DOI: 10.1016/j.bmcl.2008.10.108 BindingDB Entry DOI: 10.7270/Q22F7N98
Pfizer Global Research and Development Curated by ChEMBL					More data for this Ligand-Target Pair
Ephrin type-A receptor 2 (Homo sapiens (Human))	BDBM50255048 (3,4-Difluoro-2-(2-fluoro-4-iodo-phenylamino)-5-[(5...) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	3.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Binding affinity to ECK (unknown origin)				Bioorg Med Chem Lett 19: 226-9 (2008) Article DOI: 10.1016/j.bmcl.2008.10.108 BindingDB Entry DOI: 10.7270/Q22F7N98
Pfizer Global Research and Development Curated by ChEMBL					More data for this Ligand-Target Pair
Dual specificity protein kinase CLK1 (Homo sapiens (Human))	BDBM50255049 (5-{[2-(4-Chloro-benzenesulfonyl)-acetyl]-hydrazono...) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	3.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Binding affinity to CLK1 (unknown origin)				Bioorg Med Chem Lett 19: 226-9 (2008) Article DOI: 10.1016/j.bmcl.2008.10.108 BindingDB Entry DOI: 10.7270/Q22F7N98
Pfizer Global Research and Development Curated by ChEMBL					More data for this Ligand-Target Pair
Aurora kinase A (Homo sapiens (Human))	BDBM50255048 (3,4-Difluoro-2-(2-fluoro-4-iodo-phenylamino)-5-[(5...) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	3.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Binding affinity to Aurora A (unknown origin)				Bioorg Med Chem Lett 19: 226-9 (2008) Article DOI: 10.1016/j.bmcl.2008.10.108 BindingDB Entry DOI: 10.7270/Q22F7N98
Pfizer Global Research and Development Curated by ChEMBL					More data for this Ligand-Target Pair
Proto-oncogene tyrosine-protein kinase Src (Homo sapiens (Human))	BDBM50255049 (5-{[2-(4-Chloro-benzenesulfonyl)-acetyl]-hydrazono...) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	3.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Binding affinity to SRC (unknown origin)				Bioorg Med Chem Lett 19: 226-9 (2008) Article DOI: 10.1016/j.bmcl.2008.10.108 BindingDB Entry DOI: 10.7270/Q22F7N98
Pfizer Global Research and Development Curated by ChEMBL					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM50255048 (3,4-Difluoro-2-(2-fluoro-4-iodo-phenylamino)-5-[(5...) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	3.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Binding affinity to VEGFR2 (unknown origin)				Bioorg Med Chem Lett 19: 226-9 (2008) Article DOI: 10.1016/j.bmcl.2008.10.108 BindingDB Entry DOI: 10.7270/Q22F7N98
Pfizer Global Research and Development Curated by ChEMBL					More data for this Ligand-Target Pair
Tyrosine-protein kinase ABL1 (Homo sapiens (Human))	BDBM50255049 (5-{[2-(4-Chloro-benzenesulfonyl)-acetyl]-hydrazono...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	4.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Binding affinity to ABL (unknown origin)				Bioorg Med Chem Lett 19: 226-9 (2008) Article DOI: 10.1016/j.bmcl.2008.10.108 BindingDB Entry DOI: 10.7270/Q22F7N98
Pfizer Global Research and Development Curated by ChEMBL					More data for this Ligand-Target Pair
Aurora kinase A (Homo sapiens (Human))	BDBM50255049 (5-{[2-(4-Chloro-benzenesulfonyl)-acetyl]-hydrazono...) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	4.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Binding affinity to Aurora A (unknown origin)				Bioorg Med Chem Lett 19: 226-9 (2008) Article DOI: 10.1016/j.bmcl.2008.10.108 BindingDB Entry DOI: 10.7270/Q22F7N98
Pfizer Global Research and Development Curated by ChEMBL					More data for this Ligand-Target Pair
Proto-oncogene tyrosine-protein kinase Src (Homo sapiens (Human))	BDBM50255013 ((S)-5-((2,4-diamino-4-oxobutanamido)methyl)-3,4-di...) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	4.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Binding affinity to SRC (unknown origin)				Bioorg Med Chem Lett 19: 226-9 (2008) Article DOI: 10.1016/j.bmcl.2008.10.108 BindingDB Entry DOI: 10.7270/Q22F7N98
Pfizer Global Research and Development Curated by ChEMBL					More data for this Ligand-Target Pair
Mitogen-activated protein kinase kinase kinase 9 (Homo sapiens (Human))	BDBM50255048 (3,4-Difluoro-2-(2-fluoro-4-iodo-phenylamino)-5-[(5...) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	4.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Binding affinity to MAP3K9 (unknown origin)				Bioorg Med Chem Lett 19: 226-9 (2008) Article DOI: 10.1016/j.bmcl.2008.10.108 BindingDB Entry DOI: 10.7270/Q22F7N98
Pfizer Global Research and Development Curated by ChEMBL					More data for this Ligand-Target Pair
Tumor necrosis factor receptor superfamily member 1A (Homo sapiens (Human))	BDBM50255049 (5-{[2-(4-Chloro-benzenesulfonyl)-acetyl]-hydrazono...) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	5.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Binding affinity to TRAK-A (unknown origin)				Bioorg Med Chem Lett 19: 226-9 (2008) Article DOI: 10.1016/j.bmcl.2008.10.108 BindingDB Entry DOI: 10.7270/Q22F7N98
Pfizer Global Research and Development Curated by ChEMBL					More data for this Ligand-Target Pair
Mitogen-activated protein kinase kinase kinase 9 (Homo sapiens (Human))	BDBM50255012 (5-((4-(methylsulfonyl)benzylamino)methyl)-3,4-difl...) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	5.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Binding affinity to MAP3K9 (unknown origin)				Bioorg Med Chem Lett 19: 226-9 (2008) Article DOI: 10.1016/j.bmcl.2008.10.108 BindingDB Entry DOI: 10.7270/Q22F7N98
Pfizer Global Research and Development Curated by ChEMBL					More data for this Ligand-Target Pair
Serine/threonine-protein kinase 3 (Homo sapiens (Human))	BDBM50255013 ((S)-5-((2,4-diamino-4-oxobutanamido)methyl)-3,4-di...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	6.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Binding affinity to MST2 (unknown origin)				Bioorg Med Chem Lett 19: 226-9 (2008) Article DOI: 10.1016/j.bmcl.2008.10.108 BindingDB Entry DOI: 10.7270/Q22F7N98
Pfizer Global Research and Development Curated by ChEMBL					More data for this Ligand-Target Pair
Tyrosine-protein kinase Lck (Homo sapiens (Human))	BDBM50255049 (5-{[2-(4-Chloro-benzenesulfonyl)-acetyl]-hydrazono...) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	7.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Binding affinity to LCK (unknown origin)				Bioorg Med Chem Lett 19: 226-9 (2008) Article DOI: 10.1016/j.bmcl.2008.10.108 BindingDB Entry DOI: 10.7270/Q22F7N98
Pfizer Global Research and Development Curated by ChEMBL					More data for this Ligand-Target Pair
Mitogen-activated protein kinase kinase kinase 9 (Homo sapiens (Human))	BDBM50255049 (5-{[2-(4-Chloro-benzenesulfonyl)-acetyl]-hydrazono...) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	7.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Binding affinity to MAP3K9 (unknown origin)				Bioorg Med Chem Lett 19: 226-9 (2008) Article DOI: 10.1016/j.bmcl.2008.10.108 BindingDB Entry DOI: 10.7270/Q22F7N98
Pfizer Global Research and Development Curated by ChEMBL					More data for this Ligand-Target Pair
Tyrosine-protein kinase BTK (Homo sapiens (Human))	BDBM50255048 (3,4-Difluoro-2-(2-fluoro-4-iodo-phenylamino)-5-[(5...) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	7.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Binding affinity to BTK (unknown origin)				Bioorg Med Chem Lett 19: 226-9 (2008) Article DOI: 10.1016/j.bmcl.2008.10.108 BindingDB Entry DOI: 10.7270/Q22F7N98
Pfizer Global Research and Development Curated by ChEMBL					More data for this Ligand-Target Pair
RNA demethylase ALKBH5 (Homo sapiens)	BDBM50596051 (CHEMBL5183243) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem	Article PubMed	n/a	n/a	7.13E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details Article DOI: 10.1021/acs.jmedchem.1c01107 BindingDB Entry DOI: 10.7270/Q2QF8XWG
TBA					More data for this Ligand-Target Pair
RNA demethylase ALKBH5 (Homo sapiens)	BDBM50596052 (CHEMBL5196484) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem	Article PubMed	n/a	n/a	8.98E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details Article DOI: 10.1021/acs.jmedchem.1c01107 BindingDB Entry DOI: 10.7270/Q2QF8XWG
TBA					More data for this Ligand-Target Pair
Tumor necrosis factor receptor superfamily member 1A (Homo sapiens (Human))	BDBM50255013 ((S)-5-((2,4-diamino-4-oxobutanamido)methyl)-3,4-di...) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.30E+4	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Binding affinity to TRAK-A (unknown origin)				Bioorg Med Chem Lett 19: 226-9 (2008) Article DOI: 10.1016/j.bmcl.2008.10.108 BindingDB Entry DOI: 10.7270/Q22F7N98
Pfizer Global Research and Development Curated by ChEMBL					More data for this Ligand-Target Pair
Dual specificity protein kinase CLK1 (Homo sapiens (Human))	BDBM50255048 (3,4-Difluoro-2-(2-fluoro-4-iodo-phenylamino)-5-[(5...) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.50E+4	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Binding affinity to CLK1 (unknown origin)				Bioorg Med Chem Lett 19: 226-9 (2008) Article DOI: 10.1016/j.bmcl.2008.10.108 BindingDB Entry DOI: 10.7270/Q22F7N98
Pfizer Global Research and Development Curated by ChEMBL					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM50255012 (5-((4-(methylsulfonyl)benzylamino)methyl)-3,4-difl...) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.80E+4	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Binding affinity to VEGFR2 (unknown origin)				Bioorg Med Chem Lett 19: 226-9 (2008) Article DOI: 10.1016/j.bmcl.2008.10.108 BindingDB Entry DOI: 10.7270/Q22F7N98
Pfizer Global Research and Development Curated by ChEMBL					More data for this Ligand-Target Pair
Tumor necrosis factor receptor superfamily member 1A (Homo sapiens (Human))	BDBM50255048 (3,4-Difluoro-2-(2-fluoro-4-iodo-phenylamino)-5-[(5...) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	2.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Binding affinity to TRAK-A (unknown origin)				Bioorg Med Chem Lett 19: 226-9 (2008) Article DOI: 10.1016/j.bmcl.2008.10.108 BindingDB Entry DOI: 10.7270/Q22F7N98
Pfizer Global Research and Development Curated by ChEMBL					More data for this Ligand-Target Pair
Lysine-specific histone demethylase 1A (Homo sapiens (Human))	BDBM50113851 ((+/-)-Tranylcypromine \| 2-PCPA \| 2-Phenyl-cyclopro...) Show SMILES NC1CC1c1ccccc1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	2.48E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details Article DOI: 10.1021/acsmedchemlett.2c00126 BindingDB Entry DOI: 10.7270/Q2BC43JF
TBA					More data for this Ligand-Target Pair
Fibroblast growth factor receptor 1 (Homo sapiens (Human))	BDBM50255012 (5-((4-(methylsulfonyl)benzylamino)methyl)-3,4-difl...) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	>3.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Binding affinity to FGFR1 (unknown origin)				Bioorg Med Chem Lett 19: 226-9 (2008) Article DOI: 10.1016/j.bmcl.2008.10.108 BindingDB Entry DOI: 10.7270/Q22F7N98
Pfizer Global Research and Development Curated by ChEMBL					More data for this Ligand-Target Pair
Fibroblast growth factor receptor 1 (Homo sapiens (Human))	BDBM50255013 ((S)-5-((2,4-diamino-4-oxobutanamido)methyl)-3,4-di...) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	>3.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Binding affinity to FGFR1 (unknown origin)				Bioorg Med Chem Lett 19: 226-9 (2008) Article DOI: 10.1016/j.bmcl.2008.10.108 BindingDB Entry DOI: 10.7270/Q22F7N98
Pfizer Global Research and Development Curated by ChEMBL					More data for this Ligand-Target Pair
Fibroblast growth factor receptor 1 (Homo sapiens (Human))	BDBM50255049 (5-{[2-(4-Chloro-benzenesulfonyl)-acetyl]-hydrazono...) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	>3.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Binding affinity to FGFR1 (unknown origin)				Bioorg Med Chem Lett 19: 226-9 (2008) Article DOI: 10.1016/j.bmcl.2008.10.108 BindingDB Entry DOI: 10.7270/Q22F7N98
Pfizer Global Research and Development Curated by ChEMBL					More data for this Ligand-Target Pair
Ephrin type-A receptor 2 (Homo sapiens (Human))	BDBM50255012 (5-((4-(methylsulfonyl)benzylamino)methyl)-3,4-difl...) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	>3.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Binding affinity to ECK (unknown origin)				Bioorg Med Chem Lett 19: 226-9 (2008) Article DOI: 10.1016/j.bmcl.2008.10.108 BindingDB Entry DOI: 10.7270/Q22F7N98
Pfizer Global Research and Development Curated by ChEMBL					More data for this Ligand-Target Pair
Ephrin type-A receptor 2 (Homo sapiens (Human))	BDBM50255013 ((S)-5-((2,4-diamino-4-oxobutanamido)methyl)-3,4-di...) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	>3.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Binding affinity to ECK (unknown origin)				Bioorg Med Chem Lett 19: 226-9 (2008) Article DOI: 10.1016/j.bmcl.2008.10.108 BindingDB Entry DOI: 10.7270/Q22F7N98
Pfizer Global Research and Development Curated by ChEMBL					More data for this Ligand-Target Pair

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