Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
RAC-alpha serine/threonine-protein kinase (Homo sapiens (Human)) | BDBM50536168 (CHEMBL4574111) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 1.90 | n/a | n/a | n/a | n/a | n/a | n/a |
ArQule Inc. Curated by ChEMBL | Assay Description Inhibition of full length unphosphorylated AKT1 (1 to 480 residues) (unknown origin) expressed in baculovirus infected Sf9 insect cells using biotin-... | J Med Chem 59: 6455-69 (2016) Article DOI: 10.1021/acs.jmedchem.6b00619 BindingDB Entry DOI: 10.7270/Q2RN3CCM | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
RAC-alpha serine/threonine-protein kinase (Homo sapiens (Human)) | BDBM50536169 (CHEMBL4519558) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 2.30 | n/a | n/a | n/a | n/a | n/a | n/a |
ArQule Inc. Curated by ChEMBL | Assay Description Inhibition of full length active AKT1 (1 to 480 residues) (unknown origin) expressed in baculovirus infected Sf9 insect cells using biotin-GRPRTSSFAE... | J Med Chem 59: 6455-69 (2016) Article DOI: 10.1021/acs.jmedchem.6b00619 BindingDB Entry DOI: 10.7270/Q2RN3CCM | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
RAC-beta serine/threonine-protein kinase (Homo sapiens (Human)) | BDBM50536170 (CHEMBL4544109) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 2.5 | n/a | n/a | n/a | n/a | n/a | n/a |
ArQule Inc. Curated by ChEMBL | Assay Description Inhibition of full length unphosphorylated AKT2 (1 to 481 residues) (unknown origin) expressed in baculovirus infected Sf9 insect cells using biotin-... | J Med Chem 59: 6455-69 (2016) Article DOI: 10.1021/acs.jmedchem.6b00619 BindingDB Entry DOI: 10.7270/Q2RN3CCM | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
RAC-alpha serine/threonine-protein kinase (Homo sapiens (Human)) | BDBM50536168 (CHEMBL4574111) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 2.60 | n/a | n/a | n/a | n/a | n/a | n/a |
ArQule Inc. Curated by ChEMBL | Assay Description Inhibition of full length active AKT1 (1 to 480 residues) (unknown origin) expressed in baculovirus infected Sf9 insect cells using biotin-GRPRTSSFAE... | J Med Chem 59: 6455-69 (2016) Article DOI: 10.1021/acs.jmedchem.6b00619 BindingDB Entry DOI: 10.7270/Q2RN3CCM | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
RAC-alpha serine/threonine-protein kinase (Homo sapiens (Human)) | BDBM50536167 (CHEMBL4523032) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase PC cid PC sid UniChem | Article PubMed | n/a | n/a | 2.70 | n/a | n/a | n/a | n/a | n/a | n/a |
ArQule Inc. Curated by ChEMBL | Assay Description Inhibition of full length unphosphorylated AKT1 (1 to 480 residues) (unknown origin) expressed in baculovirus infected Sf9 insect cells using biotin-... | J Med Chem 59: 6455-69 (2016) Article DOI: 10.1021/acs.jmedchem.6b00619 BindingDB Entry DOI: 10.7270/Q2RN3CCM | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
RAC-alpha serine/threonine-protein kinase (Homo sapiens (Human)) | BDBM50536169 (CHEMBL4519558) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 2.80 | n/a | n/a | n/a | n/a | n/a | n/a |
ArQule Inc. Curated by ChEMBL | Assay Description Inhibition of full length unphosphorylated AKT1 (1 to 480 residues) (unknown origin) expressed in baculovirus infected Sf9 insect cells using biotin-... | J Med Chem 59: 6455-69 (2016) Article DOI: 10.1021/acs.jmedchem.6b00619 BindingDB Entry DOI: 10.7270/Q2RN3CCM | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
RAC-beta serine/threonine-protein kinase (Homo sapiens (Human)) | BDBM50536168 (CHEMBL4574111) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 2.80 | n/a | n/a | n/a | n/a | n/a | n/a |
ArQule Inc. Curated by ChEMBL | Assay Description Inhibition of full length active AKT2 (1 to 481 residues) (unknown origin) expressed in baculovirus infected Sf9 insect cells using biotin-GRPRTSSFAE... | J Med Chem 59: 6455-69 (2016) Article DOI: 10.1021/acs.jmedchem.6b00619 BindingDB Entry DOI: 10.7270/Q2RN3CCM | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
RAC-beta serine/threonine-protein kinase (Homo sapiens (Human)) | BDBM50536169 (CHEMBL4519558) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 3.20 | n/a | n/a | n/a | n/a | n/a | n/a |
ArQule Inc. Curated by ChEMBL | Assay Description Inhibition of full length active AKT2 (1 to 481 residues) (unknown origin) expressed in baculovirus infected Sf9 insect cells using biotin-GRPRTSSFAE... | J Med Chem 59: 6455-69 (2016) Article DOI: 10.1021/acs.jmedchem.6b00619 BindingDB Entry DOI: 10.7270/Q2RN3CCM | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
RAC-alpha serine/threonine-protein kinase (Homo sapiens (Human)) | BDBM50536172 (CHEMBL4513257) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 3.70 | n/a | n/a | n/a | n/a | n/a | n/a |
ArQule Inc. Curated by ChEMBL | Assay Description Inhibition of full length unphosphorylated AKT1 (1 to 480 residues) (unknown origin) expressed in baculovirus infected Sf9 insect cells using biotin-... | J Med Chem 59: 6455-69 (2016) Article DOI: 10.1021/acs.jmedchem.6b00619 BindingDB Entry DOI: 10.7270/Q2RN3CCM | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
RAC-gamma serine/threonine-protein kinase (Homo sapiens (Human)) | BDBM50536168 (CHEMBL4574111) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 4 | n/a | n/a | n/a | n/a | n/a | n/a |
ArQule Inc. Curated by ChEMBL | Assay Description Inhibition of full length unphosphorylated AKT3 (1 to 479 residues) (unknown origin) expressed in baculovirus infected Sf9 insect cells using biotin-... | J Med Chem 59: 6455-69 (2016) Article DOI: 10.1021/acs.jmedchem.6b00619 BindingDB Entry DOI: 10.7270/Q2RN3CCM | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
RAC-beta serine/threonine-protein kinase (Homo sapiens (Human)) | BDBM50536167 (CHEMBL4523032) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase PC cid PC sid UniChem | Article PubMed | n/a | n/a | 4.5 | n/a | n/a | n/a | n/a | n/a | n/a |
ArQule Inc. Curated by ChEMBL | Assay Description Inhibition of full length active AKT2 (1 to 481 residues) (unknown origin) expressed in baculovirus infected Sf9 insect cells using biotin-GRPRTSSFAE... | J Med Chem 59: 6455-69 (2016) Article DOI: 10.1021/acs.jmedchem.6b00619 BindingDB Entry DOI: 10.7270/Q2RN3CCM | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
RAC-alpha serine/threonine-protein kinase (Homo sapiens (Human)) | BDBM50536167 (CHEMBL4523032) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase PC cid PC sid UniChem | Article PubMed | n/a | n/a | 5 | n/a | n/a | n/a | n/a | n/a | n/a |
ArQule Inc. Curated by ChEMBL | Assay Description Inhibition of full length active AKT1 (1 to 480 residues) (unknown origin) expressed in baculovirus infected Sf9 insect cells using biotin-GRPRTSSFAE... | J Med Chem 59: 6455-69 (2016) Article DOI: 10.1021/acs.jmedchem.6b00619 BindingDB Entry DOI: 10.7270/Q2RN3CCM | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
RAC-alpha serine/threonine-protein kinase (Homo sapiens (Human)) | BDBM50397798 (CHEMBL2177836) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL MCE MMDB PC cid PC sid PDB UniChem Similars | PDB Article PubMed | n/a | n/a | 5 | n/a | n/a | n/a | n/a | n/a | n/a |
ArQule Inc. Curated by ChEMBL | Assay Description Inhibition of Akt1 (1 to 480) expressed in Sf9 cells using biotin-GRPRTSSFAEG as substrate after 20 mins by Alpha-screen assay | J Med Chem 55: 5291-310 (2012) Article DOI: 10.1021/jm300276x BindingDB Entry DOI: 10.7270/Q2NK3G5J | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (crystal) | ||||||||||||
RAC-alpha serine/threonine-protein kinase (Homo sapiens (Human)) | BDBM50397783 (CHEMBL2177833) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 5.20 | n/a | n/a | n/a | n/a | n/a | n/a |
ArQule Inc. Curated by ChEMBL | Assay Description Inhibition of Akt1 (1 to 480) expressed in Sf9 cells using biotin-GRPRTSSFAEG as substrate after 20 mins by Alpha-screen assay | J Med Chem 55: 5291-310 (2012) Article DOI: 10.1021/jm300276x BindingDB Entry DOI: 10.7270/Q2NK3G5J | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
RAC-beta serine/threonine-protein kinase (Homo sapiens (Human)) | BDBM50536168 (CHEMBL4574111) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 5.40 | n/a | n/a | n/a | n/a | n/a | n/a |
ArQule Inc. Curated by ChEMBL | Assay Description Inhibition of full length unphosphorylated AKT2 (1 to 481 residues) (unknown origin) expressed in baculovirus infected Sf9 insect cells using biotin-... | J Med Chem 59: 6455-69 (2016) Article DOI: 10.1021/acs.jmedchem.6b00619 BindingDB Entry DOI: 10.7270/Q2RN3CCM | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
RAC-gamma serine/threonine-protein kinase (Homo sapiens (Human)) | BDBM50536169 (CHEMBL4519558) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 5.40 | n/a | n/a | n/a | n/a | n/a | n/a |
ArQule Inc. Curated by ChEMBL | Assay Description Inhibition of full length unphosphorylated AKT3 (1 to 479 residues) (unknown origin) expressed in baculovirus infected Sf9 insect cells using biotin-... | J Med Chem 59: 6455-69 (2016) Article DOI: 10.1021/acs.jmedchem.6b00619 BindingDB Entry DOI: 10.7270/Q2RN3CCM | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
RAC-alpha serine/threonine-protein kinase (Homo sapiens (Human)) | BDBM50536178 (CHEMBL4528363) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 5.40 | n/a | n/a | n/a | n/a | n/a | n/a |
ArQule Inc. Curated by ChEMBL | Assay Description Inhibition of full length unphosphorylated AKT1 (1 to 480 residues) (unknown origin) expressed in baculovirus infected Sf9 insect cells using biotin-... | J Med Chem 59: 6455-69 (2016) Article DOI: 10.1021/acs.jmedchem.6b00619 BindingDB Entry DOI: 10.7270/Q2RN3CCM | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
RAC-alpha serine/threonine-protein kinase (Homo sapiens (Human)) | BDBM50536170 (CHEMBL4544109) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 6 | n/a | n/a | n/a | n/a | n/a | n/a |
ArQule Inc. Curated by ChEMBL | Assay Description Inhibition of full length unphosphorylated AKT1 (1 to 480 residues) (unknown origin) expressed in baculovirus infected Sf9 insect cells using biotin-... | J Med Chem 59: 6455-69 (2016) Article DOI: 10.1021/acs.jmedchem.6b00619 BindingDB Entry DOI: 10.7270/Q2RN3CCM | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
RAC-beta serine/threonine-protein kinase (Homo sapiens (Human)) | BDBM50536169 (CHEMBL4519558) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 7.10 | n/a | n/a | n/a | n/a | n/a | n/a |
ArQule Inc. Curated by ChEMBL | Assay Description Inhibition of full length unphosphorylated AKT2 (1 to 481 residues) (unknown origin) expressed in baculovirus infected Sf9 insect cells using biotin-... | J Med Chem 59: 6455-69 (2016) Article DOI: 10.1021/acs.jmedchem.6b00619 BindingDB Entry DOI: 10.7270/Q2RN3CCM | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
RAC-alpha serine/threonine-protein kinase (Homo sapiens (Human)) | BDBM50397780 (CHEMBL2177831) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 8 | n/a | n/a | n/a | n/a | n/a | n/a |
ArQule Inc. Curated by ChEMBL | Assay Description Inhibition of Akt1 (1 to 480) expressed in Sf9 cells using biotin-GRPRTSSFAEG as substrate after 20 mins by Alpha-screen assay | J Med Chem 55: 5291-310 (2012) Article DOI: 10.1021/jm300276x BindingDB Entry DOI: 10.7270/Q2NK3G5J | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
RAC-gamma serine/threonine-protein kinase (Homo sapiens (Human)) | BDBM50536167 (CHEMBL4523032) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | Purchase PC cid PC sid UniChem | Article PubMed | n/a | n/a | 8.10 | n/a | n/a | n/a | n/a | n/a | n/a |
ArQule Inc. Curated by ChEMBL | Assay Description Inhibition of full length unphosphorylated AKT3 (1 to 479 residues) (unknown origin) expressed in baculovirus infected Sf9 insect cells using biotin-... | J Med Chem 59: 6455-69 (2016) Article DOI: 10.1021/acs.jmedchem.6b00619 BindingDB Entry DOI: 10.7270/Q2RN3CCM | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
RAC-gamma serine/threonine-protein kinase (Homo sapiens (Human)) | BDBM50536168 (CHEMBL4574111) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 9 | n/a | n/a | n/a | n/a | n/a | n/a |
ArQule Inc. Curated by ChEMBL | Assay Description Inhibition of full length active AKT3 (1 to 479 residues) (unknown origin) expressed in baculovirus infected Sf9 insect cells using biotin-GRPRTSSFAE... | J Med Chem 59: 6455-69 (2016) Article DOI: 10.1021/acs.jmedchem.6b00619 BindingDB Entry DOI: 10.7270/Q2RN3CCM | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
RAC-alpha serine/threonine-protein kinase (Homo sapiens (Human)) | BDBM50536173 (CHEMBL4546484) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 13 | n/a | n/a | n/a | n/a | n/a | n/a |
ArQule Inc. Curated by ChEMBL | Assay Description Inhibition of full length unphosphorylated AKT1 (1 to 480 residues) (unknown origin) expressed in baculovirus infected Sf9 insect cells using biotin-... | J Med Chem 59: 6455-69 (2016) Article DOI: 10.1021/acs.jmedchem.6b00619 BindingDB Entry DOI: 10.7270/Q2RN3CCM | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
RAC-alpha serine/threonine-protein kinase (Homo sapiens (Human)) | BDBM50397800 (CHEMBL2177817) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 14 | n/a | n/a | n/a | n/a | n/a | n/a |
ArQule Inc. Curated by ChEMBL | Assay Description Inhibition of Akt1 (1 to 480) expressed in Sf9 cells using biotin-GRPRTSSFAEG as substrate after 20 mins by Alpha-screen assay | J Med Chem 55: 5291-310 (2012) Article DOI: 10.1021/jm300276x BindingDB Entry DOI: 10.7270/Q2NK3G5J | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
RAC-beta serine/threonine-protein kinase (Homo sapiens (Human)) | BDBM50536181 (CHEMBL4576518) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 14 | n/a | n/a | n/a | n/a | n/a | n/a |
ArQule Inc. Curated by ChEMBL | Assay Description Inhibition of full length unphosphorylated AKT2 (1 to 481 residues) (unknown origin) expressed in baculovirus infected Sf9 insect cells using biotin-... | J Med Chem 59: 6455-69 (2016) Article DOI: 10.1021/acs.jmedchem.6b00619 BindingDB Entry DOI: 10.7270/Q2RN3CCM | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
RAC-beta serine/threonine-protein kinase (Homo sapiens (Human)) | BDBM50536167 (CHEMBL4523032) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase PC cid PC sid UniChem | Article PubMed | n/a | n/a | 14 | n/a | n/a | n/a | n/a | n/a | n/a |
ArQule Inc. Curated by ChEMBL | Assay Description Inhibition of full length unphosphorylated AKT2 (1 to 481 residues) (unknown origin) expressed in baculovirus infected Sf9 insect cells using biotin-... | J Med Chem 59: 6455-69 (2016) Article DOI: 10.1021/acs.jmedchem.6b00619 BindingDB Entry DOI: 10.7270/Q2RN3CCM | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
RAC-alpha serine/threonine-protein kinase (Homo sapiens (Human)) | BDBM50397782 (CHEMBL2177834) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 15 | n/a | n/a | n/a | n/a | n/a | n/a |
ArQule Inc. Curated by ChEMBL | Assay Description Inhibition of Akt1 (1 to 480) expressed in Sf9 cells using biotin-GRPRTSSFAEG as substrate after 20 mins by Alpha-screen assay | J Med Chem 55: 5291-310 (2012) Article DOI: 10.1021/jm300276x BindingDB Entry DOI: 10.7270/Q2NK3G5J | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
RAC-beta serine/threonine-protein kinase (Homo sapiens (Human)) | BDBM50397794 (CHEMBL2177827) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 15 | n/a | n/a | n/a | n/a | n/a | n/a |
ArQule Inc. Curated by ChEMBL | Assay Description Inhibition of Akt2 (1 to 481) expressed in Sf9 cells using biotin-GRPRTSSFAEG as substrate after 20 mins by Alpha-screen assay | J Med Chem 55: 5291-310 (2012) Article DOI: 10.1021/jm300276x BindingDB Entry DOI: 10.7270/Q2NK3G5J | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
RAC-alpha serine/threonine-protein kinase (Homo sapiens (Human)) | BDBM50397796 (CHEMBL2177828) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 15 | n/a | n/a | n/a | n/a | n/a | n/a |
ArQule Inc. Curated by ChEMBL | Assay Description Inhibition of Akt 1 in human A2780 cells assessed as phosphorylation of Akt at T308 after 2 hrs by Western Blot analysis | J Med Chem 55: 5291-310 (2012) Article DOI: 10.1021/jm300276x BindingDB Entry DOI: 10.7270/Q2NK3G5J | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
RAC-alpha serine/threonine-protein kinase (Homo sapiens (Human)) | BDBM50397794 (CHEMBL2177827) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 16 | n/a | n/a | n/a | n/a | n/a | n/a |
ArQule Inc. Curated by ChEMBL | Assay Description Inhibition of Akt1 (1 to 480) expressed in Sf9 cells using biotin-GRPRTSSFAEG as substrate after 20 mins by Alpha-screen assay | J Med Chem 55: 5291-310 (2012) Article DOI: 10.1021/jm300276x BindingDB Entry DOI: 10.7270/Q2NK3G5J | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
RAC-gamma serine/threonine-protein kinase (Homo sapiens (Human)) | BDBM50536167 (CHEMBL4523032) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | Purchase PC cid PC sid UniChem | Article PubMed | n/a | n/a | 16 | n/a | n/a | n/a | n/a | n/a | n/a |
ArQule Inc. Curated by ChEMBL | Assay Description Inhibition of full length active AKT3 (1 to 479 residues) (unknown origin) expressed in baculovirus infected Sf9 insect cells using biotin-GRPRTSSFAE... | J Med Chem 59: 6455-69 (2016) Article DOI: 10.1021/acs.jmedchem.6b00619 BindingDB Entry DOI: 10.7270/Q2RN3CCM | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
RAC-alpha serine/threonine-protein kinase (Homo sapiens (Human)) | BDBM50536181 (CHEMBL4576518) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 17 | n/a | n/a | n/a | n/a | n/a | n/a |
ArQule Inc. Curated by ChEMBL | Assay Description Inhibition of full length unphosphorylated AKT1 (1 to 480 residues) (unknown origin) expressed in baculovirus infected Sf9 insect cells using biotin-... | J Med Chem 59: 6455-69 (2016) Article DOI: 10.1021/acs.jmedchem.6b00619 BindingDB Entry DOI: 10.7270/Q2RN3CCM | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
RAC-alpha serine/threonine-protein kinase (Homo sapiens (Human)) | BDBM50397796 (CHEMBL2177828) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 17 | n/a | n/a | n/a | n/a | n/a | n/a |
ArQule Inc. Curated by ChEMBL | Assay Description Inhibition of Akt1 (1 to 480) expressed in Sf9 cells using biotin-GRPRTSSFAEG as substrate after 20 mins by Alpha-screen assay | J Med Chem 55: 5291-310 (2012) Article DOI: 10.1021/jm300276x BindingDB Entry DOI: 10.7270/Q2NK3G5J | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
RAC-beta serine/threonine-protein kinase (Homo sapiens (Human)) | BDBM50397798 (CHEMBL2177836) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL MCE MMDB PC cid PC sid PDB UniChem Similars | Article PubMed | n/a | n/a | 18 | n/a | n/a | n/a | n/a | n/a | n/a |
ArQule Inc. Curated by ChEMBL | Assay Description Inhibition of Akt2 (1 to 481) expressed in Sf9 cells using biotin-GRPRTSSFAEG as substrate after 20 mins by Alpha-screen assay | J Med Chem 55: 5291-310 (2012) Article DOI: 10.1021/jm300276x BindingDB Entry DOI: 10.7270/Q2NK3G5J | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
RAC-gamma serine/threonine-protein kinase (Homo sapiens (Human)) | BDBM50536169 (CHEMBL4519558) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 22 | n/a | n/a | n/a | n/a | n/a | n/a |
ArQule Inc. Curated by ChEMBL | Assay Description Inhibition of full length active AKT3 (1 to 479 residues) (unknown origin) expressed in baculovirus infected Sf9 insect cells using biotin-GRPRTSSFAE... | J Med Chem 59: 6455-69 (2016) Article DOI: 10.1021/acs.jmedchem.6b00619 BindingDB Entry DOI: 10.7270/Q2RN3CCM | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
RAC-alpha serine/threonine-protein kinase (Homo sapiens (Human)) | BDBM50397790 (CHEMBL2177819) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 23 | n/a | n/a | n/a | n/a | n/a | n/a |
ArQule Inc. Curated by ChEMBL | Assay Description Inhibition of Akt1 (1 to 480) expressed in Sf9 cells using biotin-GRPRTSSFAEG as substrate after 20 mins by Alpha-screen assay | J Med Chem 55: 5291-310 (2012) Article DOI: 10.1021/jm300276x BindingDB Entry DOI: 10.7270/Q2NK3G5J | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
RAC-alpha serine/threonine-protein kinase (Homo sapiens (Human)) | BDBM50397793 (CHEMBL2177835) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 24 | n/a | n/a | n/a | n/a | n/a | n/a |
ArQule Inc. Curated by ChEMBL | Assay Description Inhibition of Akt1 (1 to 480) expressed in Sf9 cells using biotin-GRPRTSSFAEG as substrate after 20 mins by Alpha-screen assay | J Med Chem 55: 5291-310 (2012) Article DOI: 10.1021/jm300276x BindingDB Entry DOI: 10.7270/Q2NK3G5J | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
RAC-beta serine/threonine-protein kinase (Homo sapiens (Human)) | BDBM50536173 (CHEMBL4546484) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 24 | n/a | n/a | n/a | n/a | n/a | n/a |
ArQule Inc. Curated by ChEMBL | Assay Description Inhibition of full length unphosphorylated AKT2 (1 to 481 residues) (unknown origin) expressed in baculovirus infected Sf9 insect cells using biotin-... | J Med Chem 59: 6455-69 (2016) Article DOI: 10.1021/acs.jmedchem.6b00619 BindingDB Entry DOI: 10.7270/Q2RN3CCM | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
RAC-beta serine/threonine-protein kinase (Homo sapiens (Human)) | BDBM50397796 (CHEMBL2177828) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 24 | n/a | n/a | n/a | n/a | n/a | n/a |
ArQule Inc. Curated by ChEMBL | Assay Description Inhibition of Akt2 (1 to 481) expressed in Sf9 cells using biotin-GRPRTSSFAEG as substrate after 20 mins by Alpha-screen assay | J Med Chem 55: 5291-310 (2012) Article DOI: 10.1021/jm300276x BindingDB Entry DOI: 10.7270/Q2NK3G5J | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
RAC-beta serine/threonine-protein kinase (Homo sapiens (Human)) | BDBM50397792 (CHEMBL2177829) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 25 | n/a | n/a | n/a | n/a | n/a | n/a |
ArQule Inc. Curated by ChEMBL | Assay Description Inhibition of Akt2 (1 to 481) expressed in Sf9 cells using biotin-GRPRTSSFAEG as substrate after 20 mins by Alpha-screen assay | J Med Chem 55: 5291-310 (2012) Article DOI: 10.1021/jm300276x BindingDB Entry DOI: 10.7270/Q2NK3G5J | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
RAC-gamma serine/threonine-protein kinase (Homo sapiens (Human)) | BDBM50536170 (CHEMBL4544109) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 26 | n/a | n/a | n/a | n/a | n/a | n/a |
ArQule Inc. Curated by ChEMBL | Assay Description Inhibition of full length unphosphorylated AKT3 (1 to 479 residues) (unknown origin) expressed in baculovirus infected Sf9 insect cells using biotin-... | J Med Chem 59: 6455-69 (2016) Article DOI: 10.1021/acs.jmedchem.6b00619 BindingDB Entry DOI: 10.7270/Q2RN3CCM | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
RAC-alpha serine/threonine-protein kinase (Homo sapiens (Human)) | BDBM50397799 (CHEMBL2177825) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 27 | n/a | n/a | n/a | n/a | n/a | n/a |
ArQule Inc. Curated by ChEMBL | Assay Description Inhibition of Akt1 (1 to 480) expressed in Sf9 cells using biotin-GRPRTSSFAEG as substrate after 20 mins by Alpha-screen assay | J Med Chem 55: 5291-310 (2012) Article DOI: 10.1021/jm300276x BindingDB Entry DOI: 10.7270/Q2NK3G5J | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
RAC-beta serine/threonine-protein kinase (Homo sapiens (Human)) | BDBM50397783 (CHEMBL2177833) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 27 | n/a | n/a | n/a | n/a | n/a | n/a |
ArQule Inc. Curated by ChEMBL | Assay Description Inhibition of Akt2 (1 to 481) expressed in Sf9 cells using biotin-GRPRTSSFAEG as substrate after 20 mins by Alpha-screen assay | J Med Chem 55: 5291-310 (2012) Article DOI: 10.1021/jm300276x BindingDB Entry DOI: 10.7270/Q2NK3G5J | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
RAC-alpha serine/threonine-protein kinase (Homo sapiens (Human)) | BDBM50397798 (CHEMBL2177836) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL MCE MMDB PC cid PC sid PDB UniChem Similars | PDB Article PubMed | n/a | n/a | 27 | n/a | n/a | n/a | n/a | n/a | n/a |
ArQule Inc. Curated by ChEMBL | Assay Description Inhibition of Akt1 in human A2780 cells assessed as phosphorylation of Akt at S473 after 2 hrs by Western Blot analysis | J Med Chem 55: 5291-310 (2012) Article DOI: 10.1021/jm300276x BindingDB Entry DOI: 10.7270/Q2NK3G5J | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (crystal) | ||||||||||||
RAC-alpha serine/threonine-protein kinase (Homo sapiens (Human)) | BDBM50397787 (CHEMBL2177832) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 28 | n/a | n/a | n/a | n/a | n/a | n/a |
ArQule Inc. Curated by ChEMBL | Assay Description Inhibition of Akt1 (1 to 480) expressed in Sf9 cells using biotin-GRPRTSSFAEG as substrate after 20 mins by Alpha-screen assay | J Med Chem 55: 5291-310 (2012) Article DOI: 10.1021/jm300276x BindingDB Entry DOI: 10.7270/Q2NK3G5J | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
RAC-alpha serine/threonine-protein kinase (Homo sapiens (Human)) | BDBM50397788 (CHEMBL2177818) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 28 | n/a | n/a | n/a | n/a | n/a | n/a |
ArQule Inc. Curated by ChEMBL | Assay Description Inhibition of Akt1 (1 to 480) expressed in Sf9 cells using biotin-GRPRTSSFAEG as substrate after 20 mins by Alpha-screen assay | J Med Chem 55: 5291-310 (2012) Article DOI: 10.1021/jm300276x BindingDB Entry DOI: 10.7270/Q2NK3G5J | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
RAC-beta serine/threonine-protein kinase (Homo sapiens (Human)) | BDBM50397780 (CHEMBL2177831) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 30 | n/a | n/a | n/a | n/a | n/a | n/a |
ArQule Inc. Curated by ChEMBL | Assay Description Inhibition of Akt2 (1 to 481) expressed in Sf9 cells using biotin-GRPRTSSFAEG as substrate after 20 mins by Alpha-screen assay | J Med Chem 55: 5291-310 (2012) Article DOI: 10.1021/jm300276x BindingDB Entry DOI: 10.7270/Q2NK3G5J | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
RAC-alpha serine/threonine-protein kinase (Homo sapiens (Human)) | BDBM50397798 (CHEMBL2177836) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL MCE MMDB PC cid PC sid PDB UniChem Similars | PDB Article PubMed | n/a | n/a | 32 | n/a | n/a | n/a | n/a | n/a | n/a |
ArQule Inc. Curated by ChEMBL | Assay Description Inhibition of Akt 1 in human A2780 cells assessed as phosphorylation of Akt at T308 after 2 hrs by Western Blot analysis | J Med Chem 55: 5291-310 (2012) Article DOI: 10.1021/jm300276x BindingDB Entry DOI: 10.7270/Q2NK3G5J | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (crystal) | ||||||||||||
RAC-beta serine/threonine-protein kinase (Homo sapiens (Human)) | BDBM50397787 (CHEMBL2177832) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 32 | n/a | n/a | n/a | n/a | n/a | n/a |
ArQule Inc. Curated by ChEMBL | Assay Description Inhibition of Akt2 (1 to 481) expressed in Sf9 cells using biotin-GRPRTSSFAEG as substrate after 20 mins by Alpha-screen assay | J Med Chem 55: 5291-310 (2012) Article DOI: 10.1021/jm300276x BindingDB Entry DOI: 10.7270/Q2NK3G5J | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
RAC-beta serine/threonine-protein kinase (Homo sapiens (Human)) | BDBM50536172 (CHEMBL4513257) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 33 | n/a | n/a | n/a | n/a | n/a | n/a |
ArQule Inc. Curated by ChEMBL | Assay Description Inhibition of full length unphosphorylated AKT2 (1 to 481 residues) (unknown origin) expressed in baculovirus infected Sf9 insect cells using biotin-... | J Med Chem 59: 6455-69 (2016) Article DOI: 10.1021/acs.jmedchem.6b00619 BindingDB Entry DOI: 10.7270/Q2RN3CCM | |||||||||||
More data for this Ligand-Target Pair |
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