BindingDB PrimarySearch

Found 27 hits with Last Name = 'burke' and Initial = 'pj'
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Carboxypeptidase G2 (Pseudomonas aeruginosa)	BDBM50074672 ((R)-2-(4-Methoxy-phenylsulfanylcarbonylamino)-pent...) Show SMILES Show InChI	KEGG UniProtKB/TrEMBL GoogleScholar AffyNet	Purchase CHEMBL KEGG PC cid PC sid UniChem Similars	Article PubMed	300	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Imperial College of Science Curated by ChEMBL					Assay Description Inhibitory activity against bacterial carboxypeptidase G2 by Dixon plot assay				J Med Chem 42: 951-6 (1999) Article DOI: 10.1021/jm990004i BindingDB Entry DOI: 10.7270/Q2J965KN
Imperial College of Science Curated by ChEMBL					More data for this Ligand-Target Pair
Carboxypeptidase G2 (Pseudomonas aeruginosa)	BDBM50074680 (2-p-Tolylsulfanylcarbonylamino-pentanedioic acid \|...) Show SMILES Cc1ccc(SC(=O)NC(CCC(O)=O)C(O)=O)cc1 Show InChI	KEGG UniProtKB/TrEMBL GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.05E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Imperial College of Science Curated by ChEMBL					Assay Description Inhibitory activity against bacterial carboxypeptidase G2 by Dixon plot assay				J Med Chem 42: 951-6 (1999) Article DOI: 10.1021/jm990004i BindingDB Entry DOI: 10.7270/Q2J965KN
Imperial College of Science Curated by ChEMBL					More data for this Ligand-Target Pair
Carboxypeptidase G2 (Pseudomonas aeruginosa)	BDBM50074674 (2-(3-Methoxy-phenylsulfanylcarbonylamino)-pentaned...) Show SMILES COc1cccc(SC(=O)NC(CCC(O)=O)C(O)=O)c1 Show InChI	KEGG UniProtKB/TrEMBL GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.07E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Imperial College of Science Curated by ChEMBL					Assay Description Inhibitory activity against bacterial carboxypeptidase G2 by Dixon plot assay				J Med Chem 42: 951-6 (1999) Article DOI: 10.1021/jm990004i BindingDB Entry DOI: 10.7270/Q2J965KN
Imperial College of Science Curated by ChEMBL					More data for this Ligand-Target Pair
Carboxypeptidase G2 (Pseudomonas aeruginosa)	BDBM50074673 (2-(3-Amino-phenylsulfanylcarbonylamino)-pentanedio...) Show SMILES Nc1cccc(SC(=O)NC(CCC(O)=O)C(O)=O)c1 Show InChI	KEGG UniProtKB/TrEMBL GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	2.50E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Imperial College of Science Curated by ChEMBL					Assay Description Inhibitory activity against bacterial carboxypeptidase G2 by Dixon plot assay				J Med Chem 42: 951-6 (1999) Article DOI: 10.1021/jm990004i BindingDB Entry DOI: 10.7270/Q2J965KN
Imperial College of Science Curated by ChEMBL					More data for this Ligand-Target Pair
Carboxypeptidase G2 (Pseudomonas aeruginosa)	BDBM50074679 (2-(4-Amino-phenylsulfanylcarbonylamino)-pentanedio...) Show SMILES Nc1ccc(SC(=O)NC(CCC(O)=O)C(O)=O)cc1 Show InChI	KEGG UniProtKB/TrEMBL GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	5.80E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Imperial College of Science Curated by ChEMBL					Assay Description Inhibitory activity against bacterial carboxypeptidase G2 by Dixon plot assay				J Med Chem 42: 951-6 (1999) Article DOI: 10.1021/jm990004i BindingDB Entry DOI: 10.7270/Q2J965KN
Imperial College of Science Curated by ChEMBL					More data for this Ligand-Target Pair
Carboxypeptidase G2 (Pseudomonas aeruginosa)	BDBM50074678 (2-(1-Oxy-pyridin-4-ylsulfanylcarbonylamino)-pentan...) Show SMILES Show InChI	KEGG UniProtKB/TrEMBL GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	1.65E+5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Imperial College of Science Curated by ChEMBL					Assay Description Inhibitory activity against bacterial carboxypeptidase G2 by Dixon plot assay				J Med Chem 42: 951-6 (1999) Article DOI: 10.1021/jm990004i BindingDB Entry DOI: 10.7270/Q2J965KN
Imperial College of Science Curated by ChEMBL					More data for this Ligand-Target Pair
Estrogen receptor beta (Homo sapiens (Human))	BDBM17292 ((1S,10R,11S,14S,15S)-15-methyltetracyclo[8.7.0.0^{...) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	PDB Article PubMed	n/a	n/a	1.5	n/a	n/a	n/a	n/a	n/a	n/a
University of Colorado Curated by ChEMBL					Assay Description Inhibition of [3H]E2 binding to estrogen receptor alpha in MCF-7 cell lysate				J Med Chem 47: 1193-206 (2004) Article DOI: 10.1021/jm030352r BindingDB Entry DOI: 10.7270/Q2M61P0X
University of Colorado Curated by ChEMBL					More data for this Ligand-Target Pair				3D Structure (crystal)
Estrogen receptor beta (Homo sapiens (Human))	BDBM50474781 (CHEMBL19195) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	5	n/a	n/a	n/a	n/a	n/a	n/a
University of Colorado Curated by ChEMBL					Assay Description Inhibition of [3H]E2 binding to estrogen receptor alpha in MCF-7 cell lysate				J Med Chem 47: 1193-206 (2004) Article DOI: 10.1021/jm030352r BindingDB Entry DOI: 10.7270/Q2M61P0X
University of Colorado Curated by ChEMBL					More data for this Ligand-Target Pair
7-dehydrocholesterol reductase (Homo sapiens (Human))	BDBM50411320 (CHEMBL222694) Show SMILES Show InChI	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	30	n/a	n/a	n/a	n/a	n/a	n/a
University of Colorado Curated by ChEMBL					Assay Description Growth inhibition of MDA-MB-231 cells containing antiestrogen binding sites				J Med Chem 47: 6509-18 (2004) Article DOI: 10.1021/jm049496b BindingDB Entry DOI: 10.7270/Q23R0V3T
University of Colorado Curated by ChEMBL					More data for this Ligand-Target Pair
7-dehydrocholesterol reductase (Homo sapiens (Human))	BDBM50411320 (CHEMBL222694) Show SMILES Show InChI	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	30	n/a	n/a	n/a	n/a	n/a	n/a
University of Colorado Curated by ChEMBL					Assay Description Growth inhibition of MCF7 cells expressing ER and antiestrogen binding sites				J Med Chem 47: 6509-18 (2004) Article DOI: 10.1021/jm049496b BindingDB Entry DOI: 10.7270/Q23R0V3T
University of Colorado Curated by ChEMBL					More data for this Ligand-Target Pair
7-dehydrocholesterol reductase (Homo sapiens (Human))	BDBM50411320 (CHEMBL222694) Show SMILES Show InChI	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	40	n/a	n/a	n/a	n/a	n/a	n/a
University of Colorado Curated by ChEMBL					Assay Description Growth inhibition of MDA-MB-435 cells containing antiestrogen binding sites				J Med Chem 47: 6509-18 (2004) Article DOI: 10.1021/jm049496b BindingDB Entry DOI: 10.7270/Q23R0V3T
University of Colorado Curated by ChEMBL					More data for this Ligand-Target Pair
7-dehydrocholesterol reductase (Homo sapiens (Human))	BDBM50411319 (CHEMBL266892) Show SMILES Show InChI	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	50	n/a	n/a	n/a	n/a	n/a	n/a
University of Colorado Curated by ChEMBL					Assay Description Growth inhibition of MDA-MB-435 cells containing antiestrogen binding sites				J Med Chem 47: 6509-18 (2004) Article DOI: 10.1021/jm049496b BindingDB Entry DOI: 10.7270/Q23R0V3T
University of Colorado Curated by ChEMBL					More data for this Ligand-Target Pair
7-dehydrocholesterol reductase (Homo sapiens (Human))	BDBM50411320 (CHEMBL222694) Show SMILES Show InChI	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	60	n/a	n/a	n/a	n/a	n/a	n/a
University of Colorado Curated by ChEMBL					Assay Description Growth inhibition of multidrug resistant MCF7/Adr cells containing antiestrogen binding sites				J Med Chem 47: 6509-18 (2004) Article DOI: 10.1021/jm049496b BindingDB Entry DOI: 10.7270/Q23R0V3T
University of Colorado Curated by ChEMBL					More data for this Ligand-Target Pair
7-dehydrocholesterol reductase (Homo sapiens (Human))	BDBM50411319 (CHEMBL266892) Show SMILES Show InChI	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	70	n/a	n/a	n/a	n/a	n/a	n/a
University of Colorado Curated by ChEMBL					Assay Description Growth inhibition of MCF7 cells expressing ER and antiestrogen binding sites				J Med Chem 47: 6509-18 (2004) Article DOI: 10.1021/jm049496b BindingDB Entry DOI: 10.7270/Q23R0V3T
University of Colorado Curated by ChEMBL					More data for this Ligand-Target Pair
7-dehydrocholesterol reductase (Homo sapiens (Human))	BDBM50411319 (CHEMBL266892) Show SMILES Show InChI	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	80	n/a	n/a	n/a	n/a	n/a	n/a
University of Colorado Curated by ChEMBL					Assay Description Growth inhibition of MDA-MB-231 cells containing antiestrogen binding sites				J Med Chem 47: 6509-18 (2004) Article DOI: 10.1021/jm049496b BindingDB Entry DOI: 10.7270/Q23R0V3T
University of Colorado Curated by ChEMBL					More data for this Ligand-Target Pair
Estrogen receptor beta (Homo sapiens (Human))	BDBM50474779 (CHEMBL19481) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	150	n/a	n/a	n/a	n/a	n/a	n/a
University of Colorado Curated by ChEMBL					Assay Description Inhibition of [3H]E2 binding to estrogen receptor alpha in MCF-7 cell lysate				J Med Chem 47: 1193-206 (2004) Article DOI: 10.1021/jm030352r BindingDB Entry DOI: 10.7270/Q2M61P0X
University of Colorado Curated by ChEMBL					More data for this Ligand-Target Pair
Estrogen receptor beta (Homo sapiens (Human))	BDBM50474783 (CHEMBL278308) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	150	n/a	n/a	n/a	n/a	n/a	n/a
University of Colorado Curated by ChEMBL					Assay Description Inhibition of [3H]E2 binding to estrogen receptor alpha in MCF-7 cell lysate				J Med Chem 47: 1193-206 (2004) Article DOI: 10.1021/jm030352r BindingDB Entry DOI: 10.7270/Q2M61P0X
University of Colorado Curated by ChEMBL					More data for this Ligand-Target Pair
7-dehydrocholesterol reductase (Homo sapiens (Human))	BDBM22984 ((8S,10S)-10-{[(2R,4S,5S,6S)-4-amino-5-hydroxy-6-me...) Show SMILES Show InChI	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	150	n/a	n/a	n/a	n/a	n/a	n/a
University of Colorado Curated by ChEMBL					Assay Description Growth inhibition of MDA-MB-435 cells containing antiestrogen binding sites				J Med Chem 47: 6509-18 (2004) Article DOI: 10.1021/jm049496b BindingDB Entry DOI: 10.7270/Q23R0V3T
University of Colorado Curated by ChEMBL					More data for this Ligand-Target Pair
7-dehydrocholesterol reductase (Homo sapiens (Human))	BDBM22984 ((8S,10S)-10-{[(2R,4S,5S,6S)-4-amino-5-hydroxy-6-me...) Show SMILES Show InChI	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	200	n/a	n/a	n/a	n/a	n/a	n/a
University of Colorado Curated by ChEMBL					Assay Description Growth inhibition of MCF7 cells expressing ER and antiestrogen binding sites				J Med Chem 47: 6509-18 (2004) Article DOI: 10.1021/jm049496b BindingDB Entry DOI: 10.7270/Q23R0V3T
University of Colorado Curated by ChEMBL					More data for this Ligand-Target Pair
Estrogen receptor beta (Homo sapiens (Human))	BDBM50474784 (CHEMBL410193) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	200	n/a	n/a	n/a	n/a	n/a	n/a
University of Colorado Curated by ChEMBL					Assay Description Inhibition of [3H]E2 binding to estrogen receptor alpha in MCF-7 cell lysate				J Med Chem 47: 1193-206 (2004) Article DOI: 10.1021/jm030352r BindingDB Entry DOI: 10.7270/Q2M61P0X
University of Colorado Curated by ChEMBL					More data for this Ligand-Target Pair
7-dehydrocholesterol reductase (Homo sapiens (Human))	BDBM22984 ((8S,10S)-10-{[(2R,4S,5S,6S)-4-amino-5-hydroxy-6-me...) Show SMILES Show InChI	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	300	n/a	n/a	n/a	n/a	n/a	n/a
University of Colorado Curated by ChEMBL					Assay Description Growth inhibition of MDA-MB-231 cells containing antiestrogen binding sites				J Med Chem 47: 6509-18 (2004) Article DOI: 10.1021/jm049496b BindingDB Entry DOI: 10.7270/Q23R0V3T
University of Colorado Curated by ChEMBL					More data for this Ligand-Target Pair
Estrogen receptor beta (Homo sapiens (Human))	BDBM50474780 (CHEMBL266703) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	300	n/a	n/a	n/a	n/a	n/a	n/a
University of Colorado Curated by ChEMBL					Assay Description Inhibition of [3H]E2 binding to estrogen receptor alpha in MCF-7 cell lysate				J Med Chem 47: 1193-206 (2004) Article DOI: 10.1021/jm030352r BindingDB Entry DOI: 10.7270/Q2M61P0X
University of Colorado Curated by ChEMBL					More data for this Ligand-Target Pair
Estrogen receptor beta (Homo sapiens (Human))	BDBM50474785 (CHEMBL266185) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	300	n/a	n/a	n/a	n/a	n/a	n/a
University of Colorado Curated by ChEMBL					Assay Description Inhibition of [3H]E2 binding to estrogen receptor alpha in MCF-7 cell lysate				J Med Chem 47: 1193-206 (2004) Article DOI: 10.1021/jm030352r BindingDB Entry DOI: 10.7270/Q2M61P0X
University of Colorado Curated by ChEMBL					More data for this Ligand-Target Pair
Estrogen receptor beta (Homo sapiens (Human))	BDBM50474782 (CHEMBL19535) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	300	n/a	n/a	n/a	n/a	n/a	n/a
University of Colorado Curated by ChEMBL					Assay Description Inhibition of [3H]E2 binding to estrogen receptor alpha in MCF-7 cell lysate				J Med Chem 47: 1193-206 (2004) Article DOI: 10.1021/jm030352r BindingDB Entry DOI: 10.7270/Q2M61P0X
University of Colorado Curated by ChEMBL					More data for this Ligand-Target Pair
7-dehydrocholesterol reductase (Homo sapiens (Human))	BDBM50411319 (CHEMBL266892) Show SMILES Show InChI	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Colorado Curated by ChEMBL					Assay Description Growth inhibition of multidrug resistant MCF7/Adr cells containing antiestrogen binding sites				J Med Chem 47: 6509-18 (2004) Article DOI: 10.1021/jm049496b BindingDB Entry DOI: 10.7270/Q23R0V3T
University of Colorado Curated by ChEMBL					More data for this Ligand-Target Pair
Estrogen receptor beta (Homo sapiens (Human))	BDBM20607 ((2-{4-[(1Z)-1,2-diphenylbut-1-en-1-yl]phenoxy}ethy...) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	2.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Colorado Curated by ChEMBL					Assay Description Inhibition of [3H]E2 binding to estrogen receptor alpha in MCF-7 cell lysate				J Med Chem 47: 1193-206 (2004) Article DOI: 10.1021/jm030352r BindingDB Entry DOI: 10.7270/Q2M61P0X
University of Colorado Curated by ChEMBL					More data for this Ligand-Target Pair
7-dehydrocholesterol reductase (Homo sapiens (Human))	BDBM22984 ((8S,10S)-10-{[(2R,4S,5S,6S)-4-amino-5-hydroxy-6-me...) Show SMILES Show InChI	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Colorado Curated by ChEMBL					Assay Description Growth inhibition of multidrug resistant MCF7/Adr cells containing antiestrogen binding sites				J Med Chem 47: 6509-18 (2004) Article DOI: 10.1021/jm049496b BindingDB Entry DOI: 10.7270/Q23R0V3T
University of Colorado Curated by ChEMBL					More data for this Ligand-Target Pair