Compile Data Set for Download or QSAR

Found 171 hits with Last Name = 'burke-howie' and Initial = 'kj'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
D(2) dopamine receptor (Homo sapiens (Human))	BDBM21397 (8-[4-(4-fluorophenyl)-4-keto-butyl]-1-phenyl-1,3,8...) Show SMILES Fc1ccc(cc1)C(=O)CCCN1CCC2(CC1)N(CNC2=O)c1ccccc1 Show InChI InChI=1S/C23H26FN3O2/c24-19-10-8-18(9-11-19)21(28)7-4-14-26-15-12-23(13-16-26)22(29)25-17-27(23)20-5-2-1-3-6-20/h1-3,5-6,8-11H,4,7,12-17H2,(H,25,29)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid PDB UniChem Patents Similars	Article PubMed	0.125	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Oregon Health Sciences University Curated by PDSP Ki Database									Proc Natl Acad Sci U S A 86: 9762-6 (1989) Article DOI: 10.1073/pnas.86.24.9762 BindingDB Entry DOI: 10.7270/Q2W66J87
					More data for this Ligand-Target Pair
D(2) dopamine receptor (Rattus norvegicus (rat))	BDBM21397 (8-[4-(4-fluorophenyl)-4-keto-butyl]-1-phenyl-1,3,8...) Show SMILES Fc1ccc(cc1)C(=O)CCCN1CCC2(CC1)N(CNC2=O)c1ccccc1 Show InChI InChI=1S/C23H26FN3O2/c24-19-10-8-18(9-11-19)21(28)7-4-14-26-15-12-23(13-16-26)22(29)25-17-27(23)20-5-2-1-3-6-20/h1-3,5-6,8-11H,4,7,12-17H2,(H,25,29)	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid PDB UniChem Patents Similars	Article PubMed	0.350	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Oregon Health Sciences University Curated by PDSP Ki Database									Proc Natl Acad Sci U S A 86: 9762-6 (1989) Article DOI: 10.1073/pnas.86.24.9762 BindingDB Entry DOI: 10.7270/Q2W66J87
					More data for this Ligand-Target Pair
D(2) dopamine receptor (Rattus norvegicus (rat))	BDBM21397 (8-[4-(4-fluorophenyl)-4-keto-butyl]-1-phenyl-1,3,8...) Show SMILES Fc1ccc(cc1)C(=O)CCCN1CCC2(CC1)N(CNC2=O)c1ccccc1 Show InChI InChI=1S/C23H26FN3O2/c24-19-10-8-18(9-11-19)21(28)7-4-14-26-15-12-23(13-16-26)22(29)25-17-27(23)20-5-2-1-3-6-20/h1-3,5-6,8-11H,4,7,12-17H2,(H,25,29)	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid PDB UniChem Patents Similars	Article PubMed	0.560	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Oregon Health Sciences University Curated by PDSP Ki Database									Proc Natl Acad Sci U S A 86: 9762-6 (1989) Article DOI: 10.1073/pnas.86.24.9762 BindingDB Entry DOI: 10.7270/Q2W66J87
					More data for this Ligand-Target Pair
D(2) dopamine receptor (Homo sapiens (Human))	BDBM50008735 ((+)-3-(tert-butyl)-(3S,4aS,13bS)-2,3,4,4a,8,9,13b,...) Show SMILES CC(C)(C)[C@]1(O)CCN2C[C@H]3c4ccccc4CCc4cccc([C@@H]2C1)c34 Show InChI InChI=1S/C25H31NO/c1-24(2,3)25(27)13-14-26-16-21-19-9-5-4-7-17(19)11-12-18-8-6-10-20(23(18)21)22(26)15-25/h4-10,21-22,27H,11-16H2,1-3H3/t21-,22-,25-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	0.940	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Oregon Health Sciences University Curated by PDSP Ki Database									Proc Natl Acad Sci U S A 86: 9762-6 (1989) Article DOI: 10.1073/pnas.86.24.9762 BindingDB Entry DOI: 10.7270/Q2W66J87
					More data for this Ligand-Target Pair
D(2) dopamine receptor (Rattus norvegicus (rat))	BDBM50008735 ((+)-3-(tert-butyl)-(3S,4aS,13bS)-2,3,4,4a,8,9,13b,...) Show SMILES CC(C)(C)[C@]1(O)CCN2C[C@H]3c4ccccc4CCc4cccc([C@@H]2C1)c34 Show InChI InChI=1S/C25H31NO/c1-24(2,3)25(27)13-14-26-16-21-19-9-5-4-7-17(19)11-12-18-8-6-10-20(23(18)21)22(26)15-25/h4-10,21-22,27H,11-16H2,1-3H3/t21-,22-,25-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.20	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Oregon Health Sciences University Curated by PDSP Ki Database									Proc Natl Acad Sci U S A 86: 9762-6 (1989) Article DOI: 10.1073/pnas.86.24.9762 BindingDB Entry DOI: 10.7270/Q2W66J87
					More data for this Ligand-Target Pair
D(2) dopamine receptor (Rattus norvegicus (rat))	BDBM50008735 ((+)-3-(tert-butyl)-(3S,4aS,13bS)-2,3,4,4a,8,9,13b,...) Show SMILES CC(C)(C)[C@]1(O)CCN2C[C@H]3c4ccccc4CCc4cccc([C@@H]2C1)c34 Show InChI InChI=1S/C25H31NO/c1-24(2,3)25(27)13-14-26-16-21-19-9-5-4-7-17(19)11-12-18-8-6-10-20(23(18)21)22(26)15-25/h4-10,21-22,27H,11-16H2,1-3H3/t21-,22-,25-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.60	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Oregon Health Sciences University Curated by PDSP Ki Database									Proc Natl Acad Sci U S A 86: 9762-6 (1989) Article DOI: 10.1073/pnas.86.24.9762 BindingDB Entry DOI: 10.7270/Q2W66J87
					More data for this Ligand-Target Pair
D(2) dopamine receptor (Homo sapiens (Human))	BDBM21398 (4-[4-(4-Chloro-phenyl)-4-hydroxy-piperidin-1-yl]-1...) Show SMILES OC1(CCN(CCCC(=O)c2ccc(F)cc2)CC1)c1ccc(Cl)cc1 Show InChI InChI=1S/C21H23ClFNO2/c22-18-7-5-17(6-8-18)21(26)11-14-24(15-12-21)13-1-2-20(25)16-3-9-19(23)10-4-16/h3-10,26H,1-2,11-15H2	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG PC cid PC sid PDB UniChem Patents Similars	DrugBank Article PubMed	2.40	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Oregon Health Sciences University Curated by PDSP Ki Database									Proc Natl Acad Sci U S A 86: 9762-6 (1989) Article DOI: 10.1073/pnas.86.24.9762 BindingDB Entry DOI: 10.7270/Q2W66J87
					More data for this Ligand-Target Pair
D(2) dopamine receptor (Rattus norvegicus (rat))	BDBM21398 (4-[4-(4-Chloro-phenyl)-4-hydroxy-piperidin-1-yl]-1...) Show SMILES OC1(CCN(CCCC(=O)c2ccc(F)cc2)CC1)c1ccc(Cl)cc1 Show InChI InChI=1S/C21H23ClFNO2/c22-18-7-5-17(6-8-18)21(26)11-14-24(15-12-21)13-1-2-20(25)16-3-9-19(23)10-4-16/h3-10,26H,1-2,11-15H2	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG PC cid PC sid PDB UniChem Patents Similars	Article PubMed	5.10	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Oregon Health Sciences University Curated by PDSP Ki Database									Proc Natl Acad Sci U S A 86: 9762-6 (1989) Article DOI: 10.1073/pnas.86.24.9762 BindingDB Entry DOI: 10.7270/Q2W66J87
					More data for this Ligand-Target Pair
D(2) dopamine receptor (Rattus norvegicus (rat))	BDBM21398 (4-[4-(4-Chloro-phenyl)-4-hydroxy-piperidin-1-yl]-1...) Show SMILES OC1(CCN(CCCC(=O)c2ccc(F)cc2)CC1)c1ccc(Cl)cc1 Show InChI InChI=1S/C21H23ClFNO2/c22-18-7-5-17(6-8-18)21(26)11-14-24(15-12-21)13-1-2-20(25)16-3-9-19(23)10-4-16/h3-10,26H,1-2,11-15H2	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG PC cid PC sid PDB UniChem Patents Similars	Article PubMed	5.80	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Oregon Health Sciences University Curated by PDSP Ki Database									Proc Natl Acad Sci U S A 86: 9762-6 (1989) Article DOI: 10.1073/pnas.86.24.9762 BindingDB Entry DOI: 10.7270/Q2W66J87
					More data for this Ligand-Target Pair
D(2) dopamine receptor (Rattus norvegicus (rat))	BDBM11638 (CHEMBL26 | Compound 7 | N-[(1-ethylpyrrolidin-2-yl...) Show SMILES CCN1CCCC1CNC(=O)c1cc(ccc1OC)S(N)(=O)=O Show InChI InChI=1S/C15H23N3O4S/c1-3-18-8-4-5-11(18)10-17-15(19)13-9-12(23(16,20)21)6-7-14(13)22-2/h6-7,9,11H,3-5,8,10H2,1-2H3,(H,17,19)(H2,16,20,21)	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE PC cid PC sid UniChem Patents Similars	Article PubMed	160	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Oregon Health Sciences University Curated by PDSP Ki Database									Proc Natl Acad Sci U S A 86: 9762-6 (1989) Article DOI: 10.1073/pnas.86.24.9762 BindingDB Entry DOI: 10.7270/Q2W66J87
					More data for this Ligand-Target Pair
D(2) dopamine receptor (Rattus norvegicus (rat))	BDBM11638 (CHEMBL26 | Compound 7 | N-[(1-ethylpyrrolidin-2-yl...) Show SMILES CCN1CCCC1CNC(=O)c1cc(ccc1OC)S(N)(=O)=O Show InChI InChI=1S/C15H23N3O4S/c1-3-18-8-4-5-11(18)10-17-15(19)13-9-12(23(16,20)21)6-7-14(13)22-2/h6-7,9,11H,3-5,8,10H2,1-2H3,(H,17,19)(H2,16,20,21)	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE PC cid PC sid UniChem Patents Similars	Article PubMed	205	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Oregon Health Sciences University Curated by PDSP Ki Database									Proc Natl Acad Sci U S A 86: 9762-6 (1989) Article DOI: 10.1073/pnas.86.24.9762 BindingDB Entry DOI: 10.7270/Q2W66J87
					More data for this Ligand-Target Pair
D(2) dopamine receptor (Homo sapiens (Human))	BDBM11638 (CHEMBL26 | Compound 7 | N-[(1-ethylpyrrolidin-2-yl...) Show SMILES CCN1CCCC1CNC(=O)c1cc(ccc1OC)S(N)(=O)=O Show InChI InChI=1S/C15H23N3O4S/c1-3-18-8-4-5-11(18)10-17-15(19)13-9-12(23(16,20)21)6-7-14(13)22-2/h6-7,9,11H,3-5,8,10H2,1-2H3,(H,17,19)(H2,16,20,21)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE PC cid PC sid UniChem Patents Similars	DrugBank Article PubMed	206	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Oregon Health Sciences University Curated by PDSP Ki Database									Proc Natl Acad Sci U S A 86: 9762-6 (1989) Article DOI: 10.1073/pnas.86.24.9762 BindingDB Entry DOI: 10.7270/Q2W66J87
					More data for this Ligand-Target Pair
D(2) dopamine receptor (Homo sapiens (Human))	BDBM82247 (8-Chloro-3-methyl-5-phenyl-2,3,4,5-tetrahydro-1H-b...) Show SMILES CN1CCc2cc(Cl)c(O)cc2[C@H](C1)c1ccccc1 |r| Show InChI InChI=1S/C17H18ClNO/c1-19-8-7-13-9-16(18)17(20)10-14(13)15(11-19)12-5-3-2-4-6-12/h2-6,9-10,15,20H,7-8,11H2,1H3/t15-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Similars	Article PubMed	2.15E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Oregon Health Sciences University Curated by PDSP Ki Database									Proc Natl Acad Sci U S A 86: 9762-6 (1989) Article DOI: 10.1073/pnas.86.24.9762 BindingDB Entry DOI: 10.7270/Q2W66J87
					More data for this Ligand-Target Pair
D(2) dopamine receptor (Rattus norvegicus (rat))	BDBM82247 (8-Chloro-3-methyl-5-phenyl-2,3,4,5-tetrahydro-1H-b...) Show SMILES CN1CCc2cc(Cl)c(O)cc2[C@H](C1)c1ccccc1 |r| Show InChI InChI=1S/C17H18ClNO/c1-19-8-7-13-9-16(18)17(20)10-14(13)15(11-19)12-5-3-2-4-6-12/h2-6,9-10,15,20H,7-8,11H2,1H3/t15-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Similars	Article PubMed	2.50E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Oregon Health Sciences University Curated by PDSP Ki Database									Proc Natl Acad Sci U S A 86: 9762-6 (1989) Article DOI: 10.1073/pnas.86.24.9762 BindingDB Entry DOI: 10.7270/Q2W66J87
					More data for this Ligand-Target Pair
D(2) dopamine receptor (Homo sapiens (Human))	BDBM35256 ((S)-mianserin | Lerivon | MIANSERIN | MIANSERIN (+...) Show SMILES [H][C@]12CN(C)CCN1c1ccccc1Cc1ccccc21 |r| Show InChI InChI=1S/C18H20N2/c1-19-10-11-20-17-9-5-3-7-15(17)12-14-6-2-4-8-16(14)18(20)13-19/h2-9,18H,10-13H2,1H3/t18-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem Patents Similars	Article PubMed	2.69E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Oregon Health Sciences University Curated by PDSP Ki Database									Proc Natl Acad Sci U S A 86: 9762-6 (1989) Article DOI: 10.1073/pnas.86.24.9762 BindingDB Entry DOI: 10.7270/Q2W66J87
					More data for this Ligand-Target Pair
D(2) dopamine receptor (Rattus norvegicus (rat))	BDBM82247 (8-Chloro-3-methyl-5-phenyl-2,3,4,5-tetrahydro-1H-b...) Show SMILES CN1CCc2cc(Cl)c(O)cc2[C@H](C1)c1ccccc1 |r| Show InChI InChI=1S/C17H18ClNO/c1-19-8-7-13-9-16(18)17(20)10-14(13)15(11-19)12-5-3-2-4-6-12/h2-6,9-10,15,20H,7-8,11H2,1H3/t15-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Similars	Article PubMed	3.30E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Oregon Health Sciences University Curated by PDSP Ki Database									Proc Natl Acad Sci U S A 86: 9762-6 (1989) Article DOI: 10.1073/pnas.86.24.9762 BindingDB Entry DOI: 10.7270/Q2W66J87
					More data for this Ligand-Target Pair
D(2) dopamine receptor (Rattus norvegicus (rat))	BDBM35256 ((S)-mianserin | Lerivon | MIANSERIN | MIANSERIN (+...) Show SMILES [H][C@]12CN(C)CCN1c1ccccc1Cc1ccccc21 |r| Show InChI InChI=1S/C18H20N2/c1-19-10-11-20-17-9-5-3-7-15(17)12-14-6-2-4-8-16(14)18(20)13-19/h2-9,18H,10-13H2,1H3/t18-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem Patents Similars	Article PubMed	4.30E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Oregon Health Sciences University Curated by PDSP Ki Database									Proc Natl Acad Sci U S A 86: 9762-6 (1989) Article DOI: 10.1073/pnas.86.24.9762 BindingDB Entry DOI: 10.7270/Q2W66J87
					More data for this Ligand-Target Pair
D(2) dopamine receptor (Rattus norvegicus (rat))	BDBM35256 ((S)-mianserin | Lerivon | MIANSERIN | MIANSERIN (+...) Show SMILES [H][C@]12CN(C)CCN1c1ccccc1Cc1ccccc21 |r| Show InChI InChI=1S/C18H20N2/c1-19-10-11-20-17-9-5-3-7-15(17)12-14-6-2-4-8-16(14)18(20)13-19/h2-9,18H,10-13H2,1H3/t18-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem Patents Similars	Article PubMed	4.60E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Oregon Health Sciences University Curated by PDSP Ki Database									Proc Natl Acad Sci U S A 86: 9762-6 (1989) Article DOI: 10.1073/pnas.86.24.9762 BindingDB Entry DOI: 10.7270/Q2W66J87
					More data for this Ligand-Target Pair
D(2) dopamine receptor (Rattus norvegicus (rat))	BDBM50008735 ((+)-3-(tert-butyl)-(3S,4aS,13bS)-2,3,4,4a,8,9,13b,...) Show SMILES CC(C)(C)[C@]1(O)CCN2C[C@H]3c4ccccc4CCc4cccc([C@@H]2C1)c34 Show InChI InChI=1S/C25H31NO/c1-24(2,3)25(27)13-14-26-16-21-19-9-5-4-7-17(19)11-12-18-8-6-10-20(23(18)21)22(26)15-25/h4-10,21-22,27H,11-16H2,1-3H3/t21-,22-,25-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Oregon Health Sciences University Curated by PDSP Ki Database									Proc Natl Acad Sci U S A 86: 9762-6 (1989) Article DOI: 10.1073/pnas.86.24.9762 BindingDB Entry DOI: 10.7270/Q2W66J87
					More data for this Ligand-Target Pair
D(2) dopamine receptor (Rattus norvegicus (rat))	BDBM50008735 ((+)-3-(tert-butyl)-(3S,4aS,13bS)-2,3,4,4a,8,9,13b,...) Show SMILES CC(C)(C)[C@]1(O)CCN2C[C@H]3c4ccccc4CCc4cccc([C@@H]2C1)c34 Show InChI InChI=1S/C25H31NO/c1-24(2,3)25(27)13-14-26-16-21-19-9-5-4-7-17(19)11-12-18-8-6-10-20(23(18)21)22(26)15-25/h4-10,21-22,27H,11-16H2,1-3H3/t21-,22-,25-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Oregon Health Sciences University Curated by PDSP Ki Database									Proc Natl Acad Sci U S A 86: 9762-6 (1989) Article DOI: 10.1073/pnas.86.24.9762 BindingDB Entry DOI: 10.7270/Q2W66J87
					More data for this Ligand-Target Pair
Sigma non-opioid intracellular receptor 1 (Homo sapiens (Human))	BDBM50061754 (CHEMBL542487 | N-(2-Chloro-3,5-diethyl-phenyl)-N'-...) Show SMILES CCc1cccc(NC(N)=Nc2cc(CC)cc(CC)c2Cl)c1 |w:10.10| Show InChI InChI=1S/C19H24ClN3/c1-4-13-8-7-9-16(11-13)22-19(21)23-17-12-14(5-2)10-15(6-3)18(17)20/h7-12H,4-6H2,1-3H3,(H3,21,22,23)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	4.5	n/a	n/a	n/a	n/a	n/a	n/a
Cambridge NeuroScience, Inc. Curated by ChEMBL					Assay Description Binding assay for the sigma receptor sites is performed by utilizing [3H]N,N-di-o-tolylguanidine ([3H]DTG) and guinea pig brain membrane suspensions				J Med Chem 40: 4281-9 (1998) Article DOI: 10.1021/jm970459c BindingDB Entry DOI: 10.7270/Q2G161HQ
					More data for this Ligand-Target Pair
Sigma non-opioid intracellular receptor 1 (Homo sapiens (Human))	BDBM50061768 (CHEMBL553034 | N-(2-Bromo-3,5-diethyl-phenyl)-N'-(...) Show SMILES CCc1cccc(NC(N)=Nc2cc(CC)cc(CC)c2Br)c1 |w:10.10| Show InChI InChI=1S/C19H24BrN3/c1-4-13-8-7-9-16(11-13)22-19(21)23-17-12-14(5-2)10-15(6-3)18(17)20/h7-12H,4-6H2,1-3H3,(H3,21,22,23)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	5.70	n/a	n/a	n/a	n/a	n/a	n/a
Cambridge NeuroScience, Inc. Curated by ChEMBL					Assay Description Binding assay for the sigma receptor sites is performed by utilizing [3H]N,N-di-o-tolylguanidine ([3H]DTG) and guinea pig brain membrane suspensions				J Med Chem 40: 4281-9 (1998) Article DOI: 10.1021/jm970459c BindingDB Entry DOI: 10.7270/Q2G161HQ
					More data for this Ligand-Target Pair
Sigma non-opioid intracellular receptor 1 (Homo sapiens (Human))	BDBM50280995 (CHEMBL542638 | N-Adamantan-1-yl-N'-o-tolyl-acetami...) Show SMILES CC(NC12CC3CC(CC(C3)C1)C2)=Nc1ccccc1C |w:13.16,TLB:2:3:10:7.6.8,2:3:5.6.10:8,12:3:10:7.6.8,THB:4:3:5.6.10:8,4:5:3.12.11:8,12:7:3.4.11:10| Show InChI InChI=1S/C19H26N2/c1-13-5-3-4-6-18(13)20-14(2)21-19-10-15-7-16(11-19)9-17(8-15)12-19/h3-6,15-17H,7-12H2,1-2H3,(H,20,21)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article	n/a	n/a	6	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description The compound was evaluated for binding affinity against sigma opioid receptor using [3H]-DTG radioligand in guinea pig membranes				Bioorg Med Chem Lett 3: 2113-2116 (1993) Article DOI: 10.1016/S0960-894X(01)81027-1 BindingDB Entry DOI: 10.7270/Q2930T28
					More data for this Ligand-Target Pair
Sigma non-opioid intracellular receptor 1 (Homo sapiens (Human))	BDBM50061773 (CHEMBL552829 | N-(3,5-Diethyl-2-fluoro-phenyl)-N'-...) Show SMILES CCc1cccc(NC(N)=Nc2cc(CC)cc(CC)c2F)c1 |w:10.10| Show InChI InChI=1S/C19H24FN3/c1-4-13-8-7-9-16(11-13)22-19(21)23-17-12-14(5-2)10-15(6-3)18(17)20/h7-12H,4-6H2,1-3H3,(H3,21,22,23)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	7.40	n/a	n/a	n/a	n/a	n/a	n/a
Cambridge NeuroScience, Inc. Curated by ChEMBL					Assay Description Binding assay for the sigma receptor sites is performed by utilizing [3H]N,N-di-o-tolylguanidine ([3H]DTG) and guinea pig brain membrane suspensions				J Med Chem 40: 4281-9 (1998) Article DOI: 10.1021/jm970459c BindingDB Entry DOI: 10.7270/Q2G161HQ
					More data for this Ligand-Target Pair
Sigma non-opioid intracellular receptor 1 (Homo sapiens (Human))	BDBM50061807 (CHEMBL552831 | N-(3,5-Diethyl-phenyl)-N'-(3-ethyl-...) Show SMILES CCc1cccc(NC(N)=Nc2cc(CC)cc(CC)c2)c1 |w:10.10| Show InChI InChI=1S/C19H25N3/c1-4-14-8-7-9-17(11-14)21-19(20)22-18-12-15(5-2)10-16(6-3)13-18/h7-13H,4-6H2,1-3H3,(H3,20,21,22)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	8	n/a	n/a	n/a	n/a	n/a	n/a
Cambridge NeuroScience, Inc. Curated by ChEMBL					Assay Description Binding assay for the sigma receptor sites is performed by utilizing [3H]N,N-di-o-tolylguanidine ([3H]DTG) and guinea pig brain membrane suspensions				J Med Chem 40: 4281-9 (1998) Article DOI: 10.1021/jm970459c BindingDB Entry DOI: 10.7270/Q2G161HQ
					More data for this Ligand-Target Pair
Sigma non-opioid intracellular receptor 1 (Homo sapiens (Human))	BDBM50280997 (CHEMBL544054 | N-Cyclohexyl-N'-o-tolyl-acetamidine...) Show SMILES CC(NC1CCCCC1)=Nc1ccccc1C |w:9.10| Show InChI InChI=1S/C15H22N2/c1-12-8-6-7-11-15(12)17-13(2)16-14-9-4-3-5-10-14/h6-8,11,14H,3-5,9-10H2,1-2H3,(H,16,17)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article	n/a	n/a	9	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description The compound was evaluated for binding affinity against sigma opioid receptor using [3H]-DTG radioligand in guinea pig membranes				Bioorg Med Chem Lett 3: 2113-2116 (1993) Article DOI: 10.1016/S0960-894X(01)81027-1 BindingDB Entry DOI: 10.7270/Q2930T28
					More data for this Ligand-Target Pair
Sigma non-opioid intracellular receptor 1 (Homo sapiens (Human))	BDBM50280994 (CHEMBL63508 | N-Bicyclo[2.2.1]hept-2-yl-N'-o-tolyl...) Show SMILES CC(NC1CC2CCC1C2)=Nc1ccccc1C |w:10.12,THB:2:3:9:7.6| Show InChI InChI=1S/C16H22N2/c1-11-5-3-4-6-15(11)17-12(2)18-16-10-13-7-8-14(16)9-13/h3-6,13-14,16H,7-10H2,1-2H3,(H,17,18)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article	n/a	n/a	9	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description The compound was evaluated for binding affinity against sigma opioid receptor using [3H]-DTG radioligand in guinea pig membranes				Bioorg Med Chem Lett 3: 2113-2116 (1993) Article DOI: 10.1016/S0960-894X(01)81027-1 BindingDB Entry DOI: 10.7270/Q2930T28
					More data for this Ligand-Target Pair
Sigma non-opioid intracellular receptor 1 (Homo sapiens (Human))	BDBM50061756 (CHEMBL544842 | N-(3-Bromo-phenyl)-N'-(3-ethyl-phen...) Show SMILES CCc1cccc(NC(N)=Nc2cccc(Br)c2)c1 |w:10.10| Show InChI InChI=1S/C15H16BrN3/c1-2-11-5-3-7-13(9-11)18-15(17)19-14-8-4-6-12(16)10-14/h3-10H,2H2,1H3,(H3,17,18,19)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	10	n/a	n/a	n/a	n/a	n/a	n/a
Cambridge NeuroScience, Inc. Curated by ChEMBL					Assay Description Binding assay for the sigma receptor sites is performed by utilizing [3H]N,N-di-o-tolylguanidine ([3H]DTG) and guinea pig brain membrane suspensions				J Med Chem 40: 4281-9 (1998) Article DOI: 10.1021/jm970459c BindingDB Entry DOI: 10.7270/Q2G161HQ
					More data for this Ligand-Target Pair
Sigma non-opioid intracellular receptor 1 (Homo sapiens (Human))	BDBM50061746 (CHEMBL556043 | N-(3-Ethyl-phenyl)-N'-o-tolyl-guani...) Show SMILES CCc1cccc(NC(N)=Nc2ccccc2C)c1 |w:10.10| Show InChI InChI=1S/C16H19N3/c1-3-13-8-6-9-14(11-13)18-16(17)19-15-10-5-4-7-12(15)2/h4-11H,3H2,1-2H3,(H3,17,18,19)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	11	n/a	n/a	n/a	n/a	n/a	n/a
Cambridge NeuroScience, Inc. Curated by ChEMBL					Assay Description Binding assay for the sigma receptor sites is performed by utilizing [3H]N,N-di-o-tolylguanidine ([3H]DTG) and guinea pig brain membrane suspensions				J Med Chem 40: 4281-9 (1998) Article DOI: 10.1021/jm970459c BindingDB Entry DOI: 10.7270/Q2G161HQ
					More data for this Ligand-Target Pair
Sigma non-opioid intracellular receptor 1 (Homo sapiens (Human))	BDBM50061776 (CHEMBL553312 | N-(2,5-Dichloro-phenyl)-N'-(3-ethyl...) Show SMILES CCc1cccc(NC(N)=Nc2cc(Cl)ccc2Cl)c1 |w:10.10| Show InChI InChI=1S/C15H15Cl2N3/c1-2-10-4-3-5-12(8-10)19-15(18)20-14-9-11(16)6-7-13(14)17/h3-9H,2H2,1H3,(H3,18,19,20)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	12	n/a	n/a	n/a	n/a	n/a	n/a
Cambridge NeuroScience, Inc. Curated by ChEMBL					Assay Description Binding assay for the sigma receptor sites is performed by utilizing [3H]N,N-di-o-tolylguanidine ([3H]DTG) and guinea pig brain membrane suspensions				J Med Chem 40: 4281-9 (1998) Article DOI: 10.1021/jm970459c BindingDB Entry DOI: 10.7270/Q2G161HQ
					More data for this Ligand-Target Pair
Sigma non-opioid intracellular receptor 1 (Homo sapiens (Human))	BDBM50061805 (CHEMBL542491 | N-(2,3-Dichloro-phenyl)-N'-(3-ethyl...) Show SMILES CCc1cccc(NC(N)=Nc2cccc(Cl)c2Cl)c1 |w:10.10| Show InChI InChI=1S/C15H15Cl2N3/c1-2-10-5-3-6-11(9-10)19-15(18)20-13-8-4-7-12(16)14(13)17/h3-9H,2H2,1H3,(H3,18,19,20)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	13	n/a	n/a	n/a	n/a	n/a	n/a
Cambridge NeuroScience, Inc. Curated by ChEMBL					Assay Description Binding assay for the sigma receptor sites is performed by utilizing [3H]N,N-di-o-tolylguanidine ([3H]DTG) and guinea pig brain membrane suspensions				J Med Chem 40: 4281-9 (1998) Article DOI: 10.1021/jm970459c BindingDB Entry DOI: 10.7270/Q2G161HQ
					More data for this Ligand-Target Pair
Sigma non-opioid intracellular receptor 1 (Homo sapiens (Human))	BDBM50061806 (CHEMBL543433 | N-(2,6-Dichloro-phenyl)-N'-(3-ethyl...) Show SMILES CCc1cccc(NC(N)=Nc2c(Cl)cccc2Cl)c1 |w:10.10| Show InChI InChI=1S/C15H15Cl2N3/c1-2-10-5-3-6-11(9-10)19-15(18)20-14-12(16)7-4-8-13(14)17/h3-9H,2H2,1H3,(H3,18,19,20)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	14	n/a	n/a	n/a	n/a	n/a	n/a
Cambridge NeuroScience, Inc. Curated by ChEMBL					Assay Description Binding assay for the sigma receptor sites is performed by utilizing [3H]N,N-di-o-tolylguanidine ([3H]DTG) and guinea pig brain membrane suspensions				J Med Chem 40: 4281-9 (1998) Article DOI: 10.1021/jm970459c BindingDB Entry DOI: 10.7270/Q2G161HQ
					More data for this Ligand-Target Pair
Sigma non-opioid intracellular receptor 1 (Homo sapiens (Human))	BDBM50280991 (CHEMBL538754 | N,N'-Di-o-tolyl-acetamidine; hydroc...) Show SMILES CC(Nc1ccccc1C)=Nc1ccccc1C |w:10.11| Show InChI InChI=1S/C16H18N2/c1-12-8-4-6-10-15(12)17-14(3)18-16-11-7-5-9-13(16)2/h4-11H,1-3H3,(H,17,18)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article	n/a	n/a	15	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description The compound was evaluated for binding affinity against sigma opioid receptor using [3H]-DTG radioligand in guinea pig membranes				Bioorg Med Chem Lett 3: 2113-2116 (1993) Article DOI: 10.1016/S0960-894X(01)81027-1 BindingDB Entry DOI: 10.7270/Q2930T28
					More data for this Ligand-Target Pair
Sigma non-opioid intracellular receptor 1 (Homo sapiens (Human))	BDBM50061766 (CHEMBL545310 | N-(2-Chloro-phenyl)-N'-(3-ethyl-phe...) Show SMILES CCc1cccc(NC(N)=Nc2ccccc2Cl)c1 |w:10.10| Show InChI InChI=1S/C15H16ClN3/c1-2-11-6-5-7-12(10-11)18-15(17)19-14-9-4-3-8-13(14)16/h3-10H,2H2,1H3,(H3,17,18,19)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	16	n/a	n/a	n/a	n/a	n/a	n/a
Cambridge NeuroScience, Inc. Curated by ChEMBL					Assay Description Binding assay for the sigma receptor sites is performed by utilizing [3H]N,N-di-o-tolylguanidine ([3H]DTG) and guinea pig brain membrane suspensions				J Med Chem 40: 4281-9 (1998) Article DOI: 10.1021/jm970459c BindingDB Entry DOI: 10.7270/Q2G161HQ
					More data for this Ligand-Target Pair
Sigma non-opioid intracellular receptor 1 (Homo sapiens (Human))	BDBM50061795 (CHEMBL543427 | N-(2-Chloro-3-ethyl-5-methylsulfany...) Show SMILES CCc1cccc(NC(N)=Nc2cc(SC)cc(CC)c2Cl)c1 |w:10.10| Show InChI InChI=1S/C18H22ClN3S/c1-4-12-7-6-8-14(9-12)21-18(20)22-16-11-15(23-3)10-13(5-2)17(16)19/h6-11H,4-5H2,1-3H3,(H3,20,21,22)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	16	n/a	n/a	n/a	n/a	n/a	n/a
Cambridge NeuroScience, Inc. Curated by ChEMBL					Assay Description Binding assay for the sigma receptor sites is performed by utilizing [3H]N,N-di-o-tolylguanidine ([3H]DTG) and guinea pig brain membrane suspensions				J Med Chem 40: 4281-9 (1998) Article DOI: 10.1021/jm970459c BindingDB Entry DOI: 10.7270/Q2G161HQ
					More data for this Ligand-Target Pair
Sigma non-opioid intracellular receptor 1 (Homo sapiens (Human))	BDBM50280993 (CHEMBL67388 | N,N'-Di-adamantan-1-yl-acetamidine) Show SMILES CC(NC12CC3CC(CC(C3)C1)C2)=NC12CC3CC(CC(C3)C1)C2 |w:13.16,TLB:17:18:22:16.15.21,10:9:12:5.4.6,10:5:12:9.11.8,23:14:21:18.17.19,THB:17:16:22:18.23.19,8:9:4:7.12.6,8:7:4:9.11.10,23:18:14.22.15:21,TEB:13:14:21:18.17.19,13:14:16.17.21:19| Show InChI InChI=1S/C22H34N2/c1-14(23-21-8-15-2-16(9-21)4-17(3-15)10-21)24-22-11-18-5-19(12-22)7-20(6-18)13-22/h15-20H,2-13H2,1H3,(H,23,24)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article	n/a	n/a	16	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description The compound was evaluated for binding affinity against sigma opioid receptor using [3H]-DTG radioligand in guinea pig membranes				Bioorg Med Chem Lett 3: 2113-2116 (1993) Article DOI: 10.1016/S0960-894X(01)81027-1 BindingDB Entry DOI: 10.7270/Q2930T28
					More data for this Ligand-Target Pair
Sigma non-opioid intracellular receptor 1 (Homo sapiens (Human))	BDBM50061739 (CHEMBL542736 | N-(2-Chloro-3-ethyl-5-trifluorometh...) Show SMILES CCc1cccc(NC(N)=Nc2cc(cc(CC)c2Cl)C(F)(F)F)c1 |w:10.10| Show InChI InChI=1S/C18H19ClF3N3/c1-3-11-6-5-7-14(8-11)24-17(23)25-15-10-13(18(20,21)22)9-12(4-2)16(15)19/h5-10H,3-4H2,1-2H3,(H3,23,24,25)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	17	n/a	n/a	n/a	n/a	n/a	n/a
Cambridge NeuroScience, Inc. Curated by ChEMBL					Assay Description Binding assay for the sigma receptor sites is performed by utilizing [3H]N,N-di-o-tolylguanidine ([3H]DTG) and guinea pig brain membrane suspensions				J Med Chem 40: 4281-9 (1998) Article DOI: 10.1021/jm970459c BindingDB Entry DOI: 10.7270/Q2G161HQ
					More data for this Ligand-Target Pair
Sigma non-opioid intracellular receptor 1 (Homo sapiens (Human))	BDBM50061778 (CHEMBL542481 | N-(2,5-Dibromo-3-ethyl-phenyl)-N'-(...) Show SMILES CCc1cccc(NC(N)=Nc2cc(Br)cc(CC)c2Br)c1 |w:10.10| Show InChI InChI=1S/C17H19Br2N3/c1-3-11-6-5-7-14(8-11)21-17(20)22-15-10-13(18)9-12(4-2)16(15)19/h5-10H,3-4H2,1-2H3,(H3,20,21,22)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	18	n/a	n/a	n/a	n/a	n/a	n/a
Cambridge NeuroScience, Inc. Curated by ChEMBL					Assay Description Binding assay for the sigma receptor sites is performed by utilizing [3H]N,N-di-o-tolylguanidine ([3H]DTG) and guinea pig brain membrane suspensions				J Med Chem 40: 4281-9 (1998) Article DOI: 10.1021/jm970459c BindingDB Entry DOI: 10.7270/Q2G161HQ
					More data for this Ligand-Target Pair
Sigma non-opioid intracellular receptor 1 (Homo sapiens (Human))	BDBM50061764 (CHEMBL538036 | N-(2-Ethyl-phenyl)-N'-(3-ethyl-phen...) Show SMILES CCc1cccc(NC(N)=Nc2ccccc2CC)c1 |w:10.10| Show InChI InChI=1S/C17H21N3/c1-3-13-8-7-10-15(12-13)19-17(18)20-16-11-6-5-9-14(16)4-2/h5-12H,3-4H2,1-2H3,(H3,18,19,20)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	19	n/a	n/a	n/a	n/a	n/a	n/a
Cambridge NeuroScience, Inc. Curated by ChEMBL					Assay Description Binding assay for the sigma receptor sites is performed by utilizing [3H]N,N-di-o-tolylguanidine ([3H]DTG) and guinea pig brain membrane suspensions				J Med Chem 40: 4281-9 (1998) Article DOI: 10.1021/jm970459c BindingDB Entry DOI: 10.7270/Q2G161HQ
					More data for this Ligand-Target Pair
Sigma non-opioid intracellular receptor 1 (Homo sapiens (Human))	BDBM50061744 (CHEMBL553749 | N-(2-Bromo-3-ethyl-5-trifluoromethy...) Show SMILES CCc1cccc(NC(N)=Nc2cc(cc(CC)c2Br)C(F)(F)F)c1 |w:10.10| Show InChI InChI=1S/C18H19BrF3N3/c1-3-11-6-5-7-14(8-11)24-17(23)25-15-10-13(18(20,21)22)9-12(4-2)16(15)19/h5-10H,3-4H2,1-2H3,(H3,23,24,25)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	20	n/a	n/a	n/a	n/a	n/a	n/a
Cambridge NeuroScience, Inc. Curated by ChEMBL					Assay Description Binding assay for the sigma receptor sites is performed by utilizing [3H]N,N-di-o-tolylguanidine ([3H]DTG) and guinea pig brain membrane suspensions				J Med Chem 40: 4281-9 (1998) Article DOI: 10.1021/jm970459c BindingDB Entry DOI: 10.7270/Q2G161HQ
					More data for this Ligand-Target Pair
Sigma non-opioid intracellular receptor 1 (Homo sapiens (Human))	BDBM50061741 (CHEMBL543432 | N-(4-Chloro-phenyl)-N'-(3-ethyl-phe...) Show SMILES CCc1cccc(c1)N=C(N)Nc1ccc(Cl)cc1 |w:8.8| Show InChI InChI=1S/C15H16ClN3/c1-2-11-4-3-5-14(10-11)19-15(17)18-13-8-6-12(16)7-9-13/h3-10H,2H2,1H3,(H3,17,18,19)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	20	n/a	n/a	n/a	n/a	n/a	n/a
Cambridge NeuroScience, Inc. Curated by ChEMBL					Assay Description Binding assay for the sigma receptor sites is performed by utilizing [3H]N,N-di-o-tolylguanidine ([3H]DTG) and guinea pig brain membrane suspensions				J Med Chem 40: 4281-9 (1998) Article DOI: 10.1021/jm970459c BindingDB Entry DOI: 10.7270/Q2G161HQ
					More data for this Ligand-Target Pair
Sigma non-opioid intracellular receptor 1 (Homo sapiens (Human))	BDBM50061770 (CHEMBL541860 | N-(3-Ethyl-phenyl)-N'-(2-isopropyl-...) Show SMILES CCc1cccc(NC(N)=Nc2ccccc2C(C)C)c1 |w:10.10| Show InChI InChI=1S/C18H23N3/c1-4-14-8-7-9-15(12-14)20-18(19)21-17-11-6-5-10-16(17)13(2)3/h5-13H,4H2,1-3H3,(H3,19,20,21)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	21	n/a	n/a	n/a	n/a	n/a	n/a
Cambridge NeuroScience, Inc. Curated by ChEMBL					Assay Description Binding assay for the sigma receptor sites is performed by utilizing [3H]N,N-di-o-tolylguanidine ([3H]DTG) and guinea pig brain membrane suspensions				J Med Chem 40: 4281-9 (1998) Article DOI: 10.1021/jm970459c BindingDB Entry DOI: 10.7270/Q2G161HQ
					More data for this Ligand-Target Pair
Sigma non-opioid intracellular receptor 1 (Homo sapiens (Human))	BDBM50061755 (CHEMBL540841 | N-(3-Ethyl-2-fluoro-5-trifluorometh...) Show SMILES CCc1cccc(NC(N)=Nc2cc(cc(CC)c2F)C(F)(F)F)c1 |w:10.10| Show InChI InChI=1S/C18H19F4N3/c1-3-11-6-5-7-14(8-11)24-17(23)25-15-10-13(18(20,21)22)9-12(4-2)16(15)19/h5-10H,3-4H2,1-2H3,(H3,23,24,25)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	24	n/a	n/a	n/a	n/a	n/a	n/a
Cambridge NeuroScience, Inc. Curated by ChEMBL					Assay Description Binding assay for the sigma receptor sites is performed by utilizing [3H]N,N-di-o-tolylguanidine ([3H]DTG) and guinea pig brain membrane suspensions				J Med Chem 40: 4281-9 (1998) Article DOI: 10.1021/jm970459c BindingDB Entry DOI: 10.7270/Q2G161HQ
					More data for this Ligand-Target Pair
Sigma non-opioid intracellular receptor 1 (Homo sapiens (Human))	BDBM50280992 (CHEMBL67665 | N,N'-Bis-(4-bromo-2-methyl-phenyl)-a...) Show SMILES CC(Nc1ccc(Br)cc1C)=Nc1ccc(Br)cc1C |w:11.12| Show InChI InChI=1S/C16H16Br2N2/c1-10-8-13(17)4-6-15(10)19-12(3)20-16-7-5-14(18)9-11(16)2/h4-9H,1-3H3,(H,19,20)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents	Article	n/a	n/a	26	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description The compound was evaluated for binding affinity against sigma opioid receptor using [3H]-DTG radioligand in guinea pig membranes				Bioorg Med Chem Lett 3: 2113-2116 (1993) Article DOI: 10.1016/S0960-894X(01)81027-1 BindingDB Entry DOI: 10.7270/Q2930T28
					More data for this Ligand-Target Pair
Sigma non-opioid intracellular receptor 1 (Homo sapiens (Human))	BDBM50061783 (CHEMBL554355 | N-(3-Chloro-phenyl)-N'-(3-ethyl-phe...) Show SMILES CCc1cccc(NC(N)=Nc2cccc(Cl)c2)c1 |w:10.10| Show InChI InChI=1S/C15H16ClN3/c1-2-11-5-3-7-13(9-11)18-15(17)19-14-8-4-6-12(16)10-14/h3-10H,2H2,1H3,(H3,17,18,19)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	27	n/a	n/a	n/a	n/a	n/a	n/a
Cambridge NeuroScience, Inc. Curated by ChEMBL					Assay Description Binding assay for the sigma receptor sites is performed by utilizing [3H]N,N-di-o-tolylguanidine ([3H]DTG) and guinea pig brain membrane suspensions				J Med Chem 40: 4281-9 (1998) Article DOI: 10.1021/jm970459c BindingDB Entry DOI: 10.7270/Q2G161HQ
					More data for this Ligand-Target Pair
Sigma non-opioid intracellular receptor 1 (Homo sapiens (Human))	BDBM50061745 (CHEMBL543673 | N'-(2,5-Dichloro-phenyl)-N-(3-ethyl...) Show SMILES CCc1cccc(c1)N(C)C(N)=Nc1cc(Cl)ccc1Cl |w:12.13| Show InChI InChI=1S/C16H17Cl2N3/c1-3-11-5-4-6-13(9-11)21(2)16(19)20-15-10-12(17)7-8-14(15)18/h4-10H,3H2,1-2H3,(H2,19,20)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	29	n/a	n/a	n/a	n/a	n/a	n/a
Cambridge NeuroScience, Inc. Curated by ChEMBL					Assay Description Binding assay for the sigma receptor sites is performed by utilizing [3H]N,N-di-o-tolylguanidine ([3H]DTG) and guinea pig brain membrane suspensions				J Med Chem 40: 4281-9 (1998) Article DOI: 10.1021/jm970459c BindingDB Entry DOI: 10.7270/Q2G161HQ
					More data for this Ligand-Target Pair
Sigma non-opioid intracellular receptor 1 (Homo sapiens (Human))	BDBM50010747 (CHEMBL543201 | CHEMBL78777 | N,N'-Bis-(3-ethyl-phe...) Show SMILES CCc1cccc(NC(N)=Nc2cccc(CC)c2)c1 |w:10.10| Show InChI InChI=1S/C17H21N3/c1-3-13-7-5-9-15(11-13)19-17(18)20-16-10-6-8-14(4-2)12-16/h5-12H,3-4H2,1-2H3,(H3,18,19,20)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	30	n/a	n/a	n/a	n/a	n/a	n/a
Cambridge NeuroScience, Inc. Curated by ChEMBL					Assay Description Binding assay for the sigma receptor sites is performed by utilizing [3H]N,N-di-o-tolylguanidine ([3H]DTG) and guinea pig brain membrane suspensions				J Med Chem 40: 4281-9 (1998) Article DOI: 10.1021/jm970459c BindingDB Entry DOI: 10.7270/Q2G161HQ
					More data for this Ligand-Target Pair
Sigma non-opioid intracellular receptor 1 (Homo sapiens (Human))	BDBM50061762 (CHEMBL542730 | N-(2-Chloro-3-ethyl-5-methyl-phenyl...) Show SMILES CCc1cccc(NC(N)=Nc2cc(C)cc(CC)c2Cl)c1 |w:10.10| Show InChI InChI=1S/C18H22ClN3/c1-4-13-7-6-8-15(11-13)21-18(20)22-16-10-12(3)9-14(5-2)17(16)19/h6-11H,4-5H2,1-3H3,(H3,20,21,22)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	31	n/a	n/a	n/a	n/a	n/a	n/a
Cambridge NeuroScience, Inc. Curated by ChEMBL					Assay Description Binding assay for the sigma receptor sites is performed by utilizing [3H]N,N-di-o-tolylguanidine ([3H]DTG) and guinea pig brain membrane suspensions				J Med Chem 40: 4281-9 (1998) Article DOI: 10.1021/jm970459c BindingDB Entry DOI: 10.7270/Q2G161HQ
					More data for this Ligand-Target Pair
Sigma non-opioid intracellular receptor 1 (Homo sapiens (Human))	BDBM50061788 (CHEMBL543431 | N-(3,4-Dichloro-phenyl)-N'-(3-ethyl...) Show SMILES CCc1cccc(NC(N)=Nc2ccc(Cl)c(Cl)c2)c1 |w:10.10| Show InChI InChI=1S/C15H15Cl2N3/c1-2-10-4-3-5-11(8-10)19-15(18)20-12-6-7-13(16)14(17)9-12/h3-9H,2H2,1H3,(H3,18,19,20)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	32	n/a	n/a	n/a	n/a	n/a	n/a
Cambridge NeuroScience, Inc. Curated by ChEMBL					Assay Description Binding assay for the sigma receptor sites is performed by utilizing [3H]N,N-di-o-tolylguanidine ([3H]DTG) and guinea pig brain membrane suspensions				J Med Chem 40: 4281-9 (1998) Article DOI: 10.1021/jm970459c BindingDB Entry DOI: 10.7270/Q2G161HQ
					More data for this Ligand-Target Pair
Sigma non-opioid intracellular receptor 1 (Homo sapiens (Human))	BDBM81982 (CAS_97-39-2 | DITOLYLGUANIDINE | DTG | Di-o-tolylg...) Show SMILES Cc1ccccc1NC(N)=Nc1ccccc1C |w:10.11| Show InChI InChI=1S/C15H17N3/c1-11-7-3-5-9-13(11)17-15(16)18-14-10-6-4-8-12(14)2/h3-10H,1-2H3,(H3,16,17,18)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Patents Similars	Article	n/a	n/a	32	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description The compound was evaluated for binding affinity against sigma opioid receptor using [3H]-DTG radioligand in guinea pig membranes				Bioorg Med Chem Lett 3: 2113-2116 (1993) Article DOI: 10.1016/S0960-894X(01)81027-1 BindingDB Entry DOI: 10.7270/Q2930T28
					More data for this Ligand-Target Pair

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