Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
DNA polymerase beta (Homo sapiens (Human)) | BDBM50241922 (CHEMBL486991 | ddCTP SODIUM | sodium ((2S,5R)-5-(4...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL MCE KEGG PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 1.30E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
National Center for Scientific Research (CNRS)-Pierre Fabre Curated by ChEMBL | Assay Description Inhibition of human recombinant DNA polymerase beta assessed as fluorescein-12-dCTP incorporation by fluorimetry | J Nat Prod 68: 979-84 (2005) Article DOI: 10.1021/np049676o BindingDB Entry DOI: 10.7270/Q2VT1RVB | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
DNA polymerase beta (Homo sapiens (Human)) | BDBM50241929 (CHEMBL520861 | Mahureone D) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 1.20E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
National Center for Scientific Research (CNRS)-Pierre Fabre Curated by ChEMBL | Assay Description Inhibition of human recombinant DNA polymerase beta assessed as fluorescein-12-dCTP incorporation by fluorimetry | J Nat Prod 68: 979-84 (2005) Article DOI: 10.1021/np049676o BindingDB Entry DOI: 10.7270/Q2VT1RVB | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
DNA polymerase beta (Homo sapiens (Human)) | BDBM50241923 (CHEMBL521208 | mahureone A) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 2.80E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
National Center for Scientific Research (CNRS)-Pierre Fabre Curated by ChEMBL | Assay Description Inhibition of human recombinant DNA polymerase beta assessed as fluorescein-12-dCTP incorporation by fluorimetry | J Nat Prod 68: 979-84 (2005) Article DOI: 10.1021/np049676o BindingDB Entry DOI: 10.7270/Q2VT1RVB | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
DNA polymerase beta (Homo sapiens (Human)) | BDBM50241924 (CHEMBL486797 | Mahureone B) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 7.30E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
National Center for Scientific Research (CNRS)-Pierre Fabre Curated by ChEMBL | Assay Description Inhibition of human recombinant DNA polymerase beta assessed as fluorescein-12-dCTP incorporation by fluorimetry | J Nat Prod 68: 979-84 (2005) Article DOI: 10.1021/np049676o BindingDB Entry DOI: 10.7270/Q2VT1RVB | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
DNA polymerase beta (Homo sapiens (Human)) | BDBM50241930 (CHEMBL486194 | Mahureone E) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 3.42E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
National Center for Scientific Research (CNRS)-Pierre Fabre Curated by ChEMBL | Assay Description Inhibition of human recombinant DNA polymerase beta assessed as fluorescein-12-dCTP incorporation by fluorimetry | J Nat Prod 68: 979-84 (2005) Article DOI: 10.1021/np049676o BindingDB Entry DOI: 10.7270/Q2VT1RVB | |||||||||||
More data for this Ligand-Target Pair |