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Compile Data Set for Download or QSAR

Found 141 hits with Last Name = 'chang' and Initial = 'mr'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Peroxisome proliferator-activated receptor gamma


(Homo sapiens (Human))		BDBM50428854
PNG
(CHEMBL1236924)
Show SMILES Clc1ccc(c(Cl)c1)S(=O)(=O)Nc1cc(Cl)c(Oc2cnc3ccccc3c2)c(Cl)c1
Show InChI InChI=1S/C21H12Cl4N2O3S/c22-13-5-6-20(16(23)8-13)31(28,29)27-14-9-17(24)21(18(25)10-14)30-15-7-12-3-1-2-4-19(12)26-11-15/h1-11,27H
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PubMed
 10n/an/an/an/an/an/an/an/a



The Scripps Research Institute

Curated by ChEMBL


Assay Description
Displacement of [3H]rosiglitazone from human PPARgamma LBD expressed in HEK293 cells by filtration assay

J Med Chem 60: 4584-4593 (2017)


Article DOI: 10.1021/acs.jmedchem.6b01727
BindingDB Entry DOI: 10.7270/Q23J3G4S
More data for this
Ligand-Target Pair		3D
3D Structure (crystal)
Nuclear receptor ROR-beta


(Homo sapiens (Human))		BDBM50466993
PNG
(CHEMBL4289691)
Show SMILES Nc1cc(c(s1)C(=O)c1ccccc1Cl)-c1cc(Cl)cc(Cl)c1
Show InChI InChI=1S/C17H10Cl3NOS/c18-10-5-9(6-11(19)7-10)13-8-15(21)23-17(13)16(22)12-3-1-2-4-14(12)20/h1-8H,21H2
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n/an/a<10n/an/an/an/an/an/a



The Scripps Research Institute

Curated by ChEMBL


Assay Description
Displacement of [3H]-T0901317 from recombinant human His-SUMO-tagged RORbeta LBD (71 to 459 residues) expressed in Escherichia coli BL21(DE3) after 1...

Bioorg Med Chem Lett 28: 3210-3215 (2018)


Article DOI: 10.1016/j.bmcl.2018.08.017
BindingDB Entry DOI: 10.7270/Q2KW5JPB
More data for this
Ligand-Target Pair
Nuclear receptor ROR-gamma


(Homo sapiens (Human))		BDBM50460731
PNG
(CHEMBL4225808)
Show SMILES CCS(=O)(=O)c1ccc(CC(=O)Nc2nc(c(s2)C(=O)c2ccccc2Cl)-c2ccccc2Cl)cc1
Show InChI InChI=1S/C26H20Cl2N2O4S2/c1-2-36(33,34)17-13-11-16(12-14-17)15-22(31)29-26-30-23(18-7-3-5-9-20(18)27)25(35-26)24(32)19-8-4-6-10-21(19)28/h3-14H,2,15H2,1H3,(H,29,30,31)
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n/an/a 13n/an/an/an/an/an/a



The Scripps Research Institute

Curated by ChEMBL


Assay Description
Displacement of [3H]-T0901317 from recombinant human His-SUMO-tagged RORgamma LBD (265 to 518 residues) expressed in Escherichia coli BL21(DE3) at af...

Bioorg Med Chem Lett 28: 1178-1181 (2018)


Article DOI: 10.1016/j.bmcl.2018.03.001
BindingDB Entry DOI: 10.7270/Q26T0Q9G
More data for this
Ligand-Target Pair
Nuclear receptor ROR-beta


(Homo sapiens (Human))		BDBM50466987
PNG
(CHEMBL4292343)
Show SMILES CC(C)Oc1cc(Br)cc(c1)-c1ccsc1C(=O)c1ccccc1Cl
Show InChI InChI=1S/C20H16BrClO2S/c1-12(2)24-15-10-13(9-14(21)11-15)16-7-8-25-20(16)19(23)17-5-3-4-6-18(17)22/h3-12H,1-2H3
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n/an/a 15n/an/an/an/an/an/a



The Scripps Research Institute

Curated by ChEMBL


Assay Description
Displacement of [3H]-T0901317 from recombinant human His-SUMO-tagged RORbeta LBD (71 to 459 residues) expressed in Escherichia coli BL21(DE3) after 1...

Bioorg Med Chem Lett 28: 3210-3215 (2018)


Article DOI: 10.1016/j.bmcl.2018.08.017
BindingDB Entry DOI: 10.7270/Q2KW5JPB
More data for this
Ligand-Target Pair
Nuclear receptor ROR-beta


(Homo sapiens (Human))		BDBM50466992
PNG
(CHEMBL4289114)
Show SMILES FC(F)(F)c1cc(Br)cc(c1)-c1ncsc1C(=O)c1ccccc1Cl
Show InChI InChI=1S/C17H8BrClF3NOS/c18-11-6-9(5-10(7-11)17(20,21)22)14-16(25-8-23-14)15(24)12-3-1-2-4-13(12)19/h1-8H
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n/an/a 26n/an/an/an/an/an/a



The Scripps Research Institute

Curated by ChEMBL


Assay Description
Displacement of [3H]-T0901317 from recombinant human His-SUMO-tagged RORbeta LBD (71 to 459 residues) expressed in Escherichia coli BL21(DE3) after 1...

Bioorg Med Chem Lett 28: 3210-3215 (2018)


Article DOI: 10.1016/j.bmcl.2018.08.017
BindingDB Entry DOI: 10.7270/Q2KW5JPB
More data for this
Ligand-Target Pair
Nuclear receptor ROR-beta


(Homo sapiens (Human))		BDBM50467002
PNG
(CHEMBL4284016)
Show SMILES FC(F)(F)c1cccc(c1)-c1ncsc1C(=O)c1ccccc1Cl
Show InChI InChI=1S/C17H9ClF3NOS/c18-13-7-2-1-6-12(13)15(23)16-14(22-9-24-16)10-4-3-5-11(8-10)17(19,20)21/h1-9H
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n/an/a 34n/an/an/an/an/an/a



The Scripps Research Institute

Curated by ChEMBL


Assay Description
Displacement of [3H]-T0901317 from recombinant human His-SUMO-tagged RORbeta LBD (71 to 459 residues) expressed in Escherichia coli BL21(DE3) after 1...

Bioorg Med Chem Lett 28: 3210-3215 (2018)


Article DOI: 10.1016/j.bmcl.2018.08.017
BindingDB Entry DOI: 10.7270/Q2KW5JPB
More data for this
Ligand-Target Pair
Nuclear receptor ROR-beta


(Homo sapiens (Human))		BDBM50466991
PNG
(CHEMBL4276720)
Show SMILES Nc1cc(c(s1)C(=O)c1ccccc1Cl)-c1cccc(c1)C(F)(F)F
Show InChI InChI=1S/C18H11ClF3NOS/c19-14-7-2-1-6-12(14)16(24)17-13(9-15(23)25-17)10-4-3-5-11(8-10)18(20,21)22/h1-9H,23H2
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n/an/a 40n/an/an/an/an/an/a



The Scripps Research Institute

Curated by ChEMBL


Assay Description
Displacement of [3H]-T0901317 from recombinant human His-SUMO-tagged RORbeta LBD (71 to 459 residues) expressed in Escherichia coli BL21(DE3) after 1...

Bioorg Med Chem Lett 28: 3210-3215 (2018)


Article DOI: 10.1016/j.bmcl.2018.08.017
BindingDB Entry DOI: 10.7270/Q2KW5JPB
More data for this
Ligand-Target Pair
Nuclear receptor ROR-beta


(Homo sapiens (Human))		BDBM50460731
PNG
(CHEMBL4225808)
Show SMILES CCS(=O)(=O)c1ccc(CC(=O)Nc2nc(c(s2)C(=O)c2ccccc2Cl)-c2ccccc2Cl)cc1
Show InChI InChI=1S/C26H20Cl2N2O4S2/c1-2-36(33,34)17-13-11-16(12-14-17)15-22(31)29-26-30-23(18-7-3-5-9-20(18)27)25(35-26)24(32)19-8-4-6-10-21(19)28/h3-14H,2,15H2,1H3,(H,29,30,31)
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n/an/a 59n/an/an/an/an/an/a



The Scripps Research Institute

Curated by ChEMBL


Assay Description
Displacement of [3H]-T0901317 from recombinant human His-SUMO-tagged RORbeta LBD (71 to 459 residues) expressed in Escherichia coli BL21(DE3) at afte...

Bioorg Med Chem Lett 28: 1178-1181 (2018)


Article DOI: 10.1016/j.bmcl.2018.03.001
BindingDB Entry DOI: 10.7270/Q26T0Q9G
More data for this
Ligand-Target Pair
Nuclear receptor ROR-beta


(Homo sapiens (Human))		BDBM50460725
PNG
(CHEMBL4226645)
Show SMILES Nc1nc(c(s1)C(=O)c1ccccc1Cl)-c1cc(Br)cc(c1)C(F)(F)F
Show InChI InChI=1S/C17H9BrClF3N2OS/c18-10-6-8(5-9(7-10)17(20,21)22)13-15(26-16(23)24-13)14(25)11-3-1-2-4-12(11)19/h1-7H,(H2,23,24)
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n/an/a 63n/an/an/an/an/an/a



The Scripps Research Institute

Curated by ChEMBL


Assay Description
Displacement of [3H]-T0901317 from recombinant human His-SUMO-tagged RORbeta LBD (71 to 459 residues) expressed in Escherichia coli BL21(DE3) at afte...

Bioorg Med Chem Lett 28: 1178-1181 (2018)


Article DOI: 10.1016/j.bmcl.2018.03.001
BindingDB Entry DOI: 10.7270/Q26T0Q9G
More data for this
Ligand-Target Pair
Nuclear receptor ROR-gamma


(Homo sapiens (Human))		BDBM50460731
PNG
(CHEMBL4225808)
Show SMILES CCS(=O)(=O)c1ccc(CC(=O)Nc2nc(c(s2)C(=O)c2ccccc2Cl)-c2ccccc2Cl)cc1
Show InChI InChI=1S/C26H20Cl2N2O4S2/c1-2-36(33,34)17-13-11-16(12-14-17)15-22(31)29-26-30-23(18-7-3-5-9-20(18)27)25(35-26)24(32)19-8-4-6-10-21(19)28/h3-14H,2,15H2,1H3,(H,29,30,31)
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n/an/a 66n/an/an/an/an/an/a



The Scripps Research Institute

Curated by ChEMBL


Assay Description
Inverse agonist activity at GAL4-DNA binding domain-fused human RORgamma ligand binding domain expressed in HEK293T cells incubated for 20 hrs by luc...

Bioorg Med Chem Lett 28: 1178-1181 (2018)


Article DOI: 10.1016/j.bmcl.2018.03.001
BindingDB Entry DOI: 10.7270/Q26T0Q9G
More data for this
Ligand-Target Pair
Nuclear receptor ROR-beta


(Homo sapiens (Human))		BDBM50466998
PNG
(CHEMBL4291888)
Show SMILES COc1ccccc1C(=O)c1sc(N)cc1-c1cccc(c1)C(F)(F)F
Show InChI InChI=1S/C19H14F3NO2S/c1-25-15-8-3-2-7-13(15)17(24)18-14(10-16(23)26-18)11-5-4-6-12(9-11)19(20,21)22/h2-10H,23H2,1H3
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n/an/a 76n/an/an/an/an/an/a



The Scripps Research Institute

Curated by ChEMBL


Assay Description
Displacement of [3H]-T0901317 from recombinant human His-SUMO-tagged RORbeta LBD (71 to 459 residues) expressed in Escherichia coli BL21(DE3) after 1...

Bioorg Med Chem Lett 28: 3210-3215 (2018)


Article DOI: 10.1016/j.bmcl.2018.08.017
BindingDB Entry DOI: 10.7270/Q2KW5JPB
More data for this
Ligand-Target Pair
Nuclear receptor ROR-beta


(Homo sapiens (Human))		BDBM50466997
PNG
(CHEMBL4284644)
Show SMILES Clc1cc(ccn1)-c1ccsc1C(=O)c1ccccc1Cl
Show InChI InChI=1S/C16H9Cl2NOS/c17-13-4-2-1-3-12(13)15(20)16-11(6-8-21-16)10-5-7-19-14(18)9-10/h1-9H
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n/an/a 87n/an/an/an/an/an/a



The Scripps Research Institute

Curated by ChEMBL


Assay Description
Displacement of [3H]-T0901317 from recombinant human His-SUMO-tagged RORbeta LBD (71 to 459 residues) expressed in Escherichia coli BL21(DE3) after 1...

Bioorg Med Chem Lett 28: 3210-3215 (2018)


Article DOI: 10.1016/j.bmcl.2018.08.017
BindingDB Entry DOI: 10.7270/Q2KW5JPB
More data for this
Ligand-Target Pair
Nuclear receptor ROR-beta


(Homo sapiens (Human))		BDBM50460726
PNG
(CHEMBL4225823)
Show SMILES Nc1nc(c(s1)C(=O)c1ccccc1C(F)(F)F)-c1cccc(c1)C(F)(F)F
Show InChI InChI=1S/C18H10F6N2OS/c19-17(20,21)10-5-3-4-9(8-10)13-15(28-16(25)26-13)14(27)11-6-1-2-7-12(11)18(22,23)24/h1-8H,(H2,25,26)
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n/an/a 90n/an/an/an/an/an/a



The Scripps Research Institute

Curated by ChEMBL


Assay Description
Displacement of [3H]-T0901317 from recombinant human His-SUMO-tagged RORbeta LBD (71 to 459 residues) expressed in Escherichia coli BL21(DE3) at afte...

Bioorg Med Chem Lett 28: 1178-1181 (2018)


Article DOI: 10.1016/j.bmcl.2018.03.001
BindingDB Entry DOI: 10.7270/Q26T0Q9G
More data for this
Ligand-Target Pair
Nuclear receptor ROR-beta


(Homo sapiens (Human))		BDBM50467006
PNG
(CHEMBL4286904)
Show SMILES Clc1ccccc1C(=O)c1sccc1-c1cccc2ccccc12
Show InChI InChI=1S/C21H13ClOS/c22-19-11-4-3-9-18(19)20(23)21-17(12-13-24-21)16-10-5-7-14-6-1-2-8-15(14)16/h1-13H
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n/an/a 90n/an/an/an/an/an/a



The Scripps Research Institute

Curated by ChEMBL


Assay Description
Displacement of [3H]-T0901317 from recombinant human His-SUMO-tagged RORbeta LBD (71 to 459 residues) expressed in Escherichia coli BL21(DE3) after 1...

Bioorg Med Chem Lett 28: 3210-3215 (2018)


Article DOI: 10.1016/j.bmcl.2018.08.017
BindingDB Entry DOI: 10.7270/Q2KW5JPB
More data for this
Ligand-Target Pair
Nuclear receptor ROR-beta


(Homo sapiens (Human))		BDBM50467011
PNG
(CHEMBL4293341)
Show SMILES Nc1ccc(C(=O)c2ccccc2Cl)c(c1)-c1cccc(c1)C(F)(F)F
Show InChI InChI=1S/C20H13ClF3NO/c21-18-7-2-1-6-16(18)19(26)15-9-8-14(25)11-17(15)12-4-3-5-13(10-12)20(22,23)24/h1-11H,25H2
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n/an/a 90n/an/an/an/an/an/a



The Scripps Research Institute

Curated by ChEMBL


Assay Description
Displacement of [3H]-T0901317 from recombinant human His-SUMO-tagged RORbeta LBD (71 to 459 residues) expressed in Escherichia coli BL21(DE3) after 1...

Bioorg Med Chem Lett 28: 3210-3215 (2018)


Article DOI: 10.1016/j.bmcl.2018.08.017
BindingDB Entry DOI: 10.7270/Q2KW5JPB
More data for this
Ligand-Target Pair
Nuclear receptor ROR-beta


(Homo sapiens (Human))		BDBM50467004
PNG
(CHEMBL4288028)
Show SMILES COc1ccccc1C(=O)c1scnc1-c1cccc(c1)C(F)(F)F
Show InChI InChI=1S/C18H12F3NO2S/c1-24-14-8-3-2-7-13(14)16(23)17-15(22-10-25-17)11-5-4-6-12(9-11)18(19,20)21/h2-10H,1H3
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n/an/a 94n/an/an/an/an/an/a



The Scripps Research Institute

Curated by ChEMBL


Assay Description
Displacement of [3H]-T0901317 from recombinant human His-SUMO-tagged RORbeta LBD (71 to 459 residues) expressed in Escherichia coli BL21(DE3) after 1...

Bioorg Med Chem Lett 28: 3210-3215 (2018)


Article DOI: 10.1016/j.bmcl.2018.08.017
BindingDB Entry DOI: 10.7270/Q2KW5JPB
More data for this
Ligand-Target Pair
Nuclear receptor ROR-alpha


(Homo sapiens (Human))		BDBM50460731
PNG
(CHEMBL4225808)
Show SMILES CCS(=O)(=O)c1ccc(CC(=O)Nc2nc(c(s2)C(=O)c2ccccc2Cl)-c2ccccc2Cl)cc1
Show InChI InChI=1S/C26H20Cl2N2O4S2/c1-2-36(33,34)17-13-11-16(12-14-17)15-22(31)29-26-30-23(18-7-3-5-9-20(18)27)25(35-26)24(32)19-8-4-6-10-21(19)28/h3-14H,2,15H2,1H3,(H,29,30,31)
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n/an/a 110n/an/an/an/an/an/a



The Scripps Research Institute

Curated by ChEMBL


Assay Description
Inverse agonist activity at GAL4-DNA binding domain-fused human RORalpha ligand binding domain expressed in HEK293T cells incubated for 20 hrs by luc...

Bioorg Med Chem Lett 28: 1178-1181 (2018)


Article DOI: 10.1016/j.bmcl.2018.03.001
BindingDB Entry DOI: 10.7270/Q26T0Q9G
More data for this
Ligand-Target Pair
Nuclear receptor ROR-beta


(Homo sapiens (Human))		BDBM50460727
PNG
(CHEMBL4226392)
Show SMILES Nc1nc(c(s1)C(=O)c1ccccc1Br)-c1cccc(c1)C(F)(F)F
Show InChI InChI=1S/C17H10BrF3N2OS/c18-12-7-2-1-6-11(12)14(24)15-13(23-16(22)25-15)9-4-3-5-10(8-9)17(19,20)21/h1-8H,(H2,22,23)
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The Scripps Research Institute

Curated by ChEMBL


Assay Description
Displacement of [3H]-T0901317 from recombinant human His-SUMO-tagged RORbeta LBD (71 to 459 residues) expressed in Escherichia coli BL21(DE3) at afte...

Bioorg Med Chem Lett 28: 1178-1181 (2018)


Article DOI: 10.1016/j.bmcl.2018.03.001
BindingDB Entry DOI: 10.7270/Q26T0Q9G
More data for this
Ligand-Target Pair
Nuclear receptor ROR-beta


(Homo sapiens (Human))		BDBM50460730
PNG
(CHEMBL4227190)
Show SMILES Nc1nc(c(s1)C(=O)c1ccccc1Cl)-c1ccc(Cl)c(c1)C(F)(F)F
Show InChI InChI=1S/C17H9Cl2F3N2OS/c18-11-4-2-1-3-9(11)14(25)15-13(24-16(23)26-15)8-5-6-12(19)10(7-8)17(20,21)22/h1-7H,(H2,23,24)
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The Scripps Research Institute

Curated by ChEMBL


Assay Description
Displacement of [3H]-T0901317 from recombinant human His-SUMO-tagged RORbeta LBD (71 to 459 residues) expressed in Escherichia coli BL21(DE3) at afte...

Bioorg Med Chem Lett 28: 1178-1181 (2018)


Article DOI: 10.1016/j.bmcl.2018.03.001
BindingDB Entry DOI: 10.7270/Q26T0Q9G
More data for this
Ligand-Target Pair
Nuclear receptor ROR-beta


(Homo sapiens (Human))		BDBM50466990
PNG
(CHEMBL4281271)
Show SMILES COc1ccccc1C(=O)c1sc(N)cc1-c1cccc(Cl)c1
Show InChI InChI=1S/C18H14ClNO2S/c1-22-15-8-3-2-7-13(15)17(21)18-14(10-16(20)23-18)11-5-4-6-12(19)9-11/h2-10H,20H2,1H3
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The Scripps Research Institute

Curated by ChEMBL


Assay Description
Displacement of [3H]-T0901317 from recombinant human His-SUMO-tagged RORbeta LBD (71 to 459 residues) expressed in Escherichia coli BL21(DE3) after 1...

Bioorg Med Chem Lett 28: 3210-3215 (2018)


Article DOI: 10.1016/j.bmcl.2018.08.017
BindingDB Entry DOI: 10.7270/Q2KW5JPB
More data for this
Ligand-Target Pair
Nuclear receptor ROR-beta


(Homo sapiens (Human))		BDBM50460724
PNG
(CHEMBL4228640)
Show SMILES Nc1nc(c(s1)C(=O)c1c(F)cccc1C(F)(F)F)-c1cccc(c1)C(F)(F)F
Show InChI InChI=1S/C18H9F7N2OS/c19-11-6-2-5-10(18(23,24)25)12(11)14(28)15-13(27-16(26)29-15)8-3-1-4-9(7-8)17(20,21)22/h1-7H,(H2,26,27)
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The Scripps Research Institute

Curated by ChEMBL


Assay Description
Displacement of [3H]-T0901317 from recombinant human His-SUMO-tagged RORbeta LBD (71 to 459 residues) expressed in Escherichia coli BL21(DE3) at afte...

Bioorg Med Chem Lett 28: 1178-1181 (2018)


Article DOI: 10.1016/j.bmcl.2018.03.001
BindingDB Entry DOI: 10.7270/Q26T0Q9G
More data for this
Ligand-Target Pair
Nuclear receptor ROR-beta


(Homo sapiens (Human))		BDBM50460733
PNG
(CHEMBL4227927)
Show SMILES Nc1nc(c(s1)C(=O)c1ccccc1Cl)-c1cc(Cl)cc(c1)C(F)(F)F
Show InChI InChI=1S/C17H9Cl2F3N2OS/c18-10-6-8(5-9(7-10)17(20,21)22)13-15(26-16(23)24-13)14(25)11-3-1-2-4-12(11)19/h1-7H,(H2,23,24)
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The Scripps Research Institute

Curated by ChEMBL


Assay Description
Displacement of [3H]-T0901317 from recombinant human His-SUMO-tagged RORbeta LBD (71 to 459 residues) expressed in Escherichia coli BL21(DE3) at afte...

Bioorg Med Chem Lett 28: 1178-1181 (2018)


Article DOI: 10.1016/j.bmcl.2018.03.001
BindingDB Entry DOI: 10.7270/Q26T0Q9G
More data for this
Ligand-Target Pair
Nuclear receptor ROR-beta


(Homo sapiens (Human))		BDBM50460721
PNG
(CHEMBL4225264)
Show SMILES COc1ccccc1C(=O)c1sc(N)nc1-c1ccc(Cl)c(c1)C(F)(F)F
Show InChI InChI=1S/C18H12ClF3N2O2S/c1-26-13-5-3-2-4-10(13)15(25)16-14(24-17(23)27-16)9-6-7-12(19)11(8-9)18(20,21)22/h2-8H,1H3,(H2,23,24)
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The Scripps Research Institute

Curated by ChEMBL


Assay Description
Displacement of [3H]-T0901317 from recombinant human His-SUMO-tagged RORbeta LBD (71 to 459 residues) expressed in Escherichia coli BL21(DE3) at afte...

Bioorg Med Chem Lett 28: 1178-1181 (2018)


Article DOI: 10.1016/j.bmcl.2018.03.001
BindingDB Entry DOI: 10.7270/Q26T0Q9G
More data for this
Ligand-Target Pair
Nuclear receptor ROR-beta


(Homo sapiens (Human))		BDBM50460728
PNG
(CHEMBL4227867)
Show SMILES COc1ccccc1C(=O)c1sc(N)nc1-c1cc(Br)cc(c1)C(F)(F)F
Show InChI InChI=1S/C18H12BrF3N2O2S/c1-26-13-5-3-2-4-12(13)15(25)16-14(24-17(23)27-16)9-6-10(18(20,21)22)8-11(19)7-9/h2-8H,1H3,(H2,23,24)
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The Scripps Research Institute

Curated by ChEMBL


Assay Description
Displacement of [3H]-T0901317 from recombinant human His-SUMO-tagged RORbeta LBD (71 to 459 residues) expressed in Escherichia coli BL21(DE3) at afte...

Bioorg Med Chem Lett 28: 1178-1181 (2018)


Article DOI: 10.1016/j.bmcl.2018.03.001
BindingDB Entry DOI: 10.7270/Q26T0Q9G
More data for this
Ligand-Target Pair
Nuclear receptor ROR-beta


(Homo sapiens (Human))		BDBM50467003
PNG
(CHEMBL4290788)
Show SMILES FC(F)(F)c1cccc(c1)-c1ccccc1C(=O)c1ccccc1Cl
Show InChI InChI=1S/C20H12ClF3O/c21-18-11-4-3-10-17(18)19(25)16-9-2-1-8-15(16)13-6-5-7-14(12-13)20(22,23)24/h1-12H
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The Scripps Research Institute

Curated by ChEMBL


Assay Description
Displacement of [3H]-T0901317 from recombinant human His-SUMO-tagged RORbeta LBD (71 to 459 residues) expressed in Escherichia coli BL21(DE3) after 1...

Bioorg Med Chem Lett 28: 3210-3215 (2018)


Article DOI: 10.1016/j.bmcl.2018.08.017
BindingDB Entry DOI: 10.7270/Q2KW5JPB
More data for this
Ligand-Target Pair
Nuclear receptor ROR-beta


(Homo sapiens (Human))		BDBM50467007
PNG
(CHEMBL4284441)
Show SMILES COc1ccccc1C(=O)c1sccc1-c1cccc(Cl)c1
Show InChI InChI=1S/C18H13ClO2S/c1-21-16-8-3-2-7-15(16)17(20)18-14(9-10-22-18)12-5-4-6-13(19)11-12/h2-11H,1H3
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The Scripps Research Institute

Curated by ChEMBL


Assay Description
Displacement of [3H]-T0901317 from recombinant human His-SUMO-tagged RORbeta LBD (71 to 459 residues) expressed in Escherichia coli BL21(DE3) after 1...

Bioorg Med Chem Lett 28: 3210-3215 (2018)


Article DOI: 10.1016/j.bmcl.2018.08.017
BindingDB Entry DOI: 10.7270/Q2KW5JPB
More data for this
Ligand-Target Pair
Nuclear receptor ROR-beta


(Homo sapiens (Human))		BDBM50466986
PNG
(CHEMBL4276733)
Show SMILES COc1ccccc1C(=O)c1sc(N)cc1-c1cc(Cl)cc(Cl)c1
Show InChI InChI=1S/C18H13Cl2NO2S/c1-23-15-5-3-2-4-13(15)17(22)18-14(9-16(21)24-18)10-6-11(19)8-12(20)7-10/h2-9H,21H2,1H3
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The Scripps Research Institute

Curated by ChEMBL


Assay Description
Displacement of [3H]-T0901317 from recombinant human His-SUMO-tagged RORbeta LBD (71 to 459 residues) expressed in Escherichia coli BL21(DE3) after 1...

Bioorg Med Chem Lett 28: 3210-3215 (2018)


Article DOI: 10.1016/j.bmcl.2018.08.017
BindingDB Entry DOI: 10.7270/Q2KW5JPB
More data for this
Ligand-Target Pair
Nuclear receptor ROR-beta


(Homo sapiens (Human))		BDBM50466989
PNG
(CHEMBL4288937)
Show SMILES COc1ccccc1C(=O)c1sccc1-c1cccc(c1)C(F)(F)F
Show InChI InChI=1S/C19H13F3O2S/c1-24-16-8-3-2-7-15(16)17(23)18-14(9-10-25-18)12-5-4-6-13(11-12)19(20,21)22/h2-11H,1H3
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The Scripps Research Institute

Curated by ChEMBL


Assay Description
Displacement of [3H]-T0901317 from recombinant human His-SUMO-tagged RORbeta LBD (71 to 459 residues) expressed in Escherichia coli BL21(DE3) after 1...

Bioorg Med Chem Lett 28: 3210-3215 (2018)


Article DOI: 10.1016/j.bmcl.2018.08.017
BindingDB Entry DOI: 10.7270/Q2KW5JPB
More data for this
Ligand-Target Pair
Nuclear receptor ROR-beta


(Homo sapiens (Human))		BDBM50467010
PNG
(CHEMBL4285419)
Show SMILES FC(F)(F)c1cccc(c1)-c1ccsc1C(=O)c1ccccc1Cl
Show InChI InChI=1S/C18H10ClF3OS/c19-15-7-2-1-6-14(15)16(23)17-13(8-9-24-17)11-4-3-5-12(10-11)18(20,21)22/h1-10H
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The Scripps Research Institute

Curated by ChEMBL


Assay Description
Displacement of [3H]-T0901317 from recombinant human His-SUMO-tagged RORbeta LBD (71 to 459 residues) expressed in Escherichia coli BL21(DE3) after 1...

Bioorg Med Chem Lett 28: 3210-3215 (2018)


Article DOI: 10.1016/j.bmcl.2018.08.017
BindingDB Entry DOI: 10.7270/Q2KW5JPB
More data for this
Ligand-Target Pair
Nuclear receptor ROR-beta


(Homo sapiens (Human))		BDBM50467008
PNG
(CHEMBL4281036)
Show SMILES COc1ccccc1C(=O)c1sccc1-c1ccnc(Cl)c1
Show InChI InChI=1S/C17H12ClNO2S/c1-21-14-5-3-2-4-13(14)16(20)17-12(7-9-22-17)11-6-8-19-15(18)10-11/h2-10H,1H3
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The Scripps Research Institute

Curated by ChEMBL


Assay Description
Displacement of [3H]-T0901317 from recombinant human His-SUMO-tagged RORbeta LBD (71 to 459 residues) expressed in Escherichia coli BL21(DE3) after 1...

Bioorg Med Chem Lett 28: 3210-3215 (2018)


Article DOI: 10.1016/j.bmcl.2018.08.017
BindingDB Entry DOI: 10.7270/Q2KW5JPB
More data for this
Ligand-Target Pair
Nuclear receptor ROR-beta


(Homo sapiens (Human))		BDBM50466996
PNG
(CHEMBL4292696)
Show SMILES Nc1cc(c(s1)C(=O)c1ccccc1Cl)-c1cc(cc(c1)C(F)(F)F)C(F)(F)F
Show InChI InChI=1S/C19H10ClF6NOS/c20-14-4-2-1-3-12(14)16(28)17-13(8-15(27)29-17)9-5-10(18(21,22)23)7-11(6-9)19(24,25)26/h1-8H,27H2
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The Scripps Research Institute

Curated by ChEMBL


Assay Description
Displacement of [3H]-T0901317 from recombinant human His-SUMO-tagged RORbeta LBD (71 to 459 residues) expressed in Escherichia coli BL21(DE3) after 1...

Bioorg Med Chem Lett 28: 3210-3215 (2018)


Article DOI: 10.1016/j.bmcl.2018.08.017
BindingDB Entry DOI: 10.7270/Q2KW5JPB
More data for this
Ligand-Target Pair
Nuclear receptor ROR-beta


(Homo sapiens (Human))		BDBM50460729
PNG
(CHEMBL4226071)
Show SMILES Nc1nc(c(s1)C(=O)c1ccccc1Cl)-c1cccc(Cl)c1
Show InChI InChI=1S/C16H10Cl2N2OS/c17-10-5-3-4-9(8-10)13-15(22-16(19)20-13)14(21)11-6-1-2-7-12(11)18/h1-8H,(H2,19,20)
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The Scripps Research Institute

Curated by ChEMBL


Assay Description
Displacement of [3H]-T0901317 from recombinant human His-SUMO-tagged RORbeta LBD (71 to 459 residues) expressed in Escherichia coli BL21(DE3) at afte...

Bioorg Med Chem Lett 28: 1178-1181 (2018)


Article DOI: 10.1016/j.bmcl.2018.03.001
BindingDB Entry DOI: 10.7270/Q26T0Q9G
More data for this
Ligand-Target Pair
Nuclear receptor ROR-beta


(Homo sapiens (Human))		BDBM50460735
PNG
(CHEMBL4226334)
Show SMILES Nc1nc(c(s1)C(=O)c1ccccc1Cl)-c1ccc(Br)c(c1)C(F)(F)F
Show InChI InChI=1S/C17H9BrClF3N2OS/c18-11-6-5-8(7-10(11)17(20,21)22)13-15(26-16(23)24-13)14(25)9-3-1-2-4-12(9)19/h1-7H,(H2,23,24)
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The Scripps Research Institute

Curated by ChEMBL


Assay Description
Displacement of [3H]-T0901317 from recombinant human His-SUMO-tagged RORbeta LBD (71 to 459 residues) expressed in Escherichia coli BL21(DE3) at afte...

Bioorg Med Chem Lett 28: 1178-1181 (2018)


Article DOI: 10.1016/j.bmcl.2018.03.001
BindingDB Entry DOI: 10.7270/Q26T0Q9G
More data for this
Ligand-Target Pair
Nuclear receptor ROR-beta


(Homo sapiens (Human))		BDBM50460736
PNG
(CHEMBL4225424)
Show SMILES COc1ccccc1C(=O)c1sc(N)nc1-c1cc(cc(c1)C(F)(F)F)C(F)(F)F
Show InChI InChI=1S/C19H12F6N2O2S/c1-29-13-5-3-2-4-12(13)15(28)16-14(27-17(26)30-16)9-6-10(18(20,21)22)8-11(7-9)19(23,24)25/h2-8H,1H3,(H2,26,27)
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The Scripps Research Institute

Curated by ChEMBL


Assay Description
Displacement of [3H]-T0901317 from recombinant human His-SUMO-tagged RORbeta LBD (71 to 459 residues) expressed in Escherichia coli BL21(DE3) at afte...

Bioorg Med Chem Lett 28: 1178-1181 (2018)


Article DOI: 10.1016/j.bmcl.2018.03.001
BindingDB Entry DOI: 10.7270/Q26T0Q9G
More data for this
Ligand-Target Pair
Nuclear receptor ROR-beta


(Homo sapiens (Human))		BDBM50460722
PNG
(CHEMBL4227134)
Show SMILES Nc1nc(c(s1)C(=O)c1ccccc1Cl)-c1cc(cc(c1)C(F)(F)F)C(F)(F)F
Show InChI InChI=1S/C18H9ClF6N2OS/c19-12-4-2-1-3-11(12)14(28)15-13(27-16(26)29-15)8-5-9(17(20,21)22)7-10(6-8)18(23,24)25/h1-7H,(H2,26,27)
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The Scripps Research Institute

Curated by ChEMBL


Assay Description
Displacement of [3H]-T0901317 from recombinant human His-SUMO-tagged RORbeta LBD (71 to 459 residues) expressed in Escherichia coli BL21(DE3) at afte...

Bioorg Med Chem Lett 28: 1178-1181 (2018)


Article DOI: 10.1016/j.bmcl.2018.03.001
BindingDB Entry DOI: 10.7270/Q26T0Q9G
More data for this
Ligand-Target Pair
Nuclear receptor ROR-gamma


(Homo sapiens (Human))		BDBM50467006
PNG
(CHEMBL4286904)
Show SMILES Clc1ccccc1C(=O)c1sccc1-c1cccc2ccccc12
Show InChI InChI=1S/C21H13ClOS/c22-19-11-4-3-9-18(19)20(23)21-17(12-13-24-21)16-10-5-7-14-6-1-2-8-15(14)16/h1-13H
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The Scripps Research Institute

Curated by ChEMBL


Assay Description
Displacement of [3H]-T0901317 from recombinant human His-SUMO-tagged RORgamma LBD (265 to 518 residues) expressed in Escherichia coli BL21(DE3) after...

Bioorg Med Chem Lett 28: 3210-3215 (2018)


Article DOI: 10.1016/j.bmcl.2018.08.017
BindingDB Entry DOI: 10.7270/Q2KW5JPB
More data for this
Ligand-Target Pair
Nuclear receptor ROR-beta


(Homo sapiens (Human))		BDBM50467009
PNG
(CHEMBL4284673)
Show SMILES COc1ccccc1C(=O)c1sc(N)cc1-c1ccnc(Cl)c1
Show InChI InChI=1S/C17H13ClN2O2S/c1-22-13-5-3-2-4-11(13)16(21)17-12(9-15(19)23-17)10-6-7-20-14(18)8-10/h2-9H,19H2,1H3
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The Scripps Research Institute

Curated by ChEMBL


Assay Description
Displacement of [3H]-T0901317 from recombinant human His-SUMO-tagged RORbeta LBD (71 to 459 residues) expressed in Escherichia coli BL21(DE3) after 1...

Bioorg Med Chem Lett 28: 3210-3215 (2018)


Article DOI: 10.1016/j.bmcl.2018.08.017
BindingDB Entry DOI: 10.7270/Q2KW5JPB
More data for this
Ligand-Target Pair
Nuclear receptor ROR-beta


(Homo sapiens (Human))		BDBM50467005
PNG
(CHEMBL4277389)
Show SMILES Clc1ccccc1C(=O)c1sccc1-c1cccc(c1)-c1ccccc1
Show InChI InChI=1S/C23H15ClOS/c24-21-12-5-4-11-20(21)22(25)23-19(13-14-26-23)18-10-6-9-17(15-18)16-7-2-1-3-8-16/h1-15H
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The Scripps Research Institute

Curated by ChEMBL


Assay Description
Displacement of [3H]-T0901317 from recombinant human His-SUMO-tagged RORbeta LBD (71 to 459 residues) expressed in Escherichia coli BL21(DE3) after 1...

Bioorg Med Chem Lett 28: 3210-3215 (2018)


Article DOI: 10.1016/j.bmcl.2018.08.017
BindingDB Entry DOI: 10.7270/Q2KW5JPB
More data for this
Ligand-Target Pair
Nuclear receptor ROR-beta


(Homo sapiens (Human))		BDBM50460734
PNG
(CHEMBL4228057)
Show SMILES COc1ccccc1C(=O)c1sc(N)nc1-c1cccc(c1)C(F)(F)F
Show InChI InChI=1S/C18H13F3N2O2S/c1-25-13-8-3-2-7-12(13)15(24)16-14(23-17(22)26-16)10-5-4-6-11(9-10)18(19,20)21/h2-9H,1H3,(H2,22,23)
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The Scripps Research Institute

Curated by ChEMBL


Assay Description
Displacement of [3H]-T0901317 from recombinant human His-SUMO-tagged RORbeta LBD (71 to 459 residues) expressed in Escherichia coli BL21(DE3) at afte...

Bioorg Med Chem Lett 28: 1178-1181 (2018)


Article DOI: 10.1016/j.bmcl.2018.03.001
BindingDB Entry DOI: 10.7270/Q26T0Q9G
More data for this
Ligand-Target Pair
Nuclear receptor ROR-beta


(Homo sapiens (Human))		BDBM50467001
PNG
(CHEMBL4285780)
Show SMILES Clc1ccccc1C(=O)c1sccc1-c1ccc2OCOc2c1
Show InChI InChI=1S/C18H11ClO3S/c19-14-4-2-1-3-13(14)17(20)18-12(7-8-23-18)11-5-6-15-16(9-11)22-10-21-15/h1-9H,10H2
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n/an/a 380n/an/an/an/an/an/a



The Scripps Research Institute

Curated by ChEMBL


Assay Description
Displacement of [3H]-T0901317 from recombinant human His-SUMO-tagged RORbeta LBD (71 to 459 residues) expressed in Escherichia coli BL21(DE3) after 1...

Bioorg Med Chem Lett 28: 3210-3215 (2018)


Article DOI: 10.1016/j.bmcl.2018.08.017
BindingDB Entry DOI: 10.7270/Q2KW5JPB
More data for this
Ligand-Target Pair
Nuclear receptor ROR-beta


(Homo sapiens (Human))		BDBM50460720
PNG
(CHEMBL4228577)
Show SMILES Nc1nc(c(s1)C(=O)c1c(F)cccc1Cl)-c1cccc(c1)C(F)(F)F
Show InChI InChI=1S/C17H9ClF4N2OS/c18-10-5-2-6-11(19)12(10)14(25)15-13(24-16(23)26-15)8-3-1-4-9(7-8)17(20,21)22/h1-7H,(H2,23,24)
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n/an/a 410n/an/an/an/an/an/a



The Scripps Research Institute

Curated by ChEMBL


Assay Description
Displacement of [3H]-T0901317 from recombinant human His-SUMO-tagged RORbeta LBD (71 to 459 residues) expressed in Escherichia coli BL21(DE3) at afte...

Bioorg Med Chem Lett 28: 1178-1181 (2018)


Article DOI: 10.1016/j.bmcl.2018.03.001
BindingDB Entry DOI: 10.7270/Q26T0Q9G
More data for this
Ligand-Target Pair
Nuclear receptor ROR-beta


(Homo sapiens (Human))		BDBM50460732
PNG
(CHEMBL4227440)
Show SMILES Nc1nc(c(s1)C(=O)c1ccccc1Cl)-c1cccc(Br)c1
Show InChI InChI=1S/C16H10BrClN2OS/c17-10-5-3-4-9(8-10)13-15(22-16(19)20-13)14(21)11-6-1-2-7-12(11)18/h1-8H,(H2,19,20)
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n/an/a 410n/an/an/an/an/an/a



The Scripps Research Institute

Curated by ChEMBL


Assay Description
Displacement of [3H]-T0901317 from recombinant human His-SUMO-tagged RORbeta LBD (71 to 459 residues) expressed in Escherichia coli BL21(DE3) at afte...

Bioorg Med Chem Lett 28: 1178-1181 (2018)


Article DOI: 10.1016/j.bmcl.2018.03.001
BindingDB Entry DOI: 10.7270/Q26T0Q9G
More data for this
Ligand-Target Pair
Nuclear receptor ROR-gamma


(Homo sapiens (Human))		BDBM50466987
PNG
(CHEMBL4292343)
Show SMILES CC(C)Oc1cc(Br)cc(c1)-c1ccsc1C(=O)c1ccccc1Cl
Show InChI InChI=1S/C20H16BrClO2S/c1-12(2)24-15-10-13(9-14(21)11-15)16-7-8-25-20(16)19(23)17-5-3-4-6-18(17)22/h3-12H,1-2H3
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n/an/a 460n/an/an/an/an/an/a



The Scripps Research Institute

Curated by ChEMBL


Assay Description
Displacement of [3H]-T0901317 from recombinant human His-SUMO-tagged RORgamma LBD (265 to 518 residues) expressed in Escherichia coli BL21(DE3) after...

Bioorg Med Chem Lett 28: 3210-3215 (2018)


Article DOI: 10.1016/j.bmcl.2018.08.017
BindingDB Entry DOI: 10.7270/Q2KW5JPB
More data for this
Ligand-Target Pair
Nuclear receptor ROR-beta


(Homo sapiens (Human))		BDBM50466985
PNG
(CHEMBL4293998)
Show SMILES Clc1ccc(cc1Cl)-c1ccsc1C(=O)c1ccccc1Cl
Show InChI InChI=1S/C17H9Cl3OS/c18-13-4-2-1-3-12(13)16(21)17-11(7-8-22-17)10-5-6-14(19)15(20)9-10/h1-9H
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n/an/a 470n/an/an/an/an/an/a



The Scripps Research Institute

Curated by ChEMBL


Assay Description
Displacement of [3H]-T0901317 from recombinant human His-SUMO-tagged RORbeta LBD (71 to 459 residues) expressed in Escherichia coli BL21(DE3) after 1...

Bioorg Med Chem Lett 28: 3210-3215 (2018)


Article DOI: 10.1016/j.bmcl.2018.08.017
BindingDB Entry DOI: 10.7270/Q2KW5JPB
More data for this
Ligand-Target Pair
Nuclear receptor ROR-beta


(Homo sapiens (Human))		BDBM50466994
PNG
(CHEMBL4283486)
Show SMILES Clc1cccc(c1)-c1ccsc1C(=O)c1ccccc1Cl
Show InChI InChI=1S/C17H10Cl2OS/c18-12-5-3-4-11(10-12)13-8-9-21-17(13)16(20)14-6-1-2-7-15(14)19/h1-10H
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n/an/a 570n/an/an/an/an/an/a



The Scripps Research Institute

Curated by ChEMBL


Assay Description
Displacement of [3H]-T0901317 from recombinant human His-SUMO-tagged RORbeta LBD (71 to 459 residues) expressed in Escherichia coli BL21(DE3) after 1...

Bioorg Med Chem Lett 28: 3210-3215 (2018)


Article DOI: 10.1016/j.bmcl.2018.08.017
BindingDB Entry DOI: 10.7270/Q2KW5JPB
More data for this
Ligand-Target Pair
Nuclear receptor ROR-beta


(Homo sapiens (Human))		BDBM50460723
PNG
(CHEMBL4229273)
Show SMILES Nc1nc(c(s1)C(=O)c1ccccc1Cl)-c1cccc(c1)C(F)(F)F
Show InChI InChI=1S/C17H10ClF3N2OS/c18-12-7-2-1-6-11(12)14(24)15-13(23-16(22)25-15)9-4-3-5-10(8-9)17(19,20)21/h1-8H,(H2,22,23)
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n/an/a 610n/an/an/an/an/an/a



The Scripps Research Institute

Curated by ChEMBL


Assay Description
Displacement of [3H]-T0901317 from recombinant human His-SUMO-tagged RORbeta LBD (71 to 459 residues) expressed in Escherichia coli BL21(DE3) after 1...

Bioorg Med Chem Lett 28: 3210-3215 (2018)


Article DOI: 10.1016/j.bmcl.2018.08.017
BindingDB Entry DOI: 10.7270/Q2KW5JPB
More data for this
Ligand-Target Pair
Nuclear receptor ROR-beta


(Homo sapiens (Human))		BDBM50460723
PNG
(CHEMBL4229273)
Show SMILES Nc1nc(c(s1)C(=O)c1ccccc1Cl)-c1cccc(c1)C(F)(F)F
Show InChI InChI=1S/C17H10ClF3N2OS/c18-12-7-2-1-6-11(12)14(24)15-13(23-16(22)25-15)9-4-3-5-10(8-9)17(19,20)21/h1-8H,(H2,22,23)
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n/an/a 610n/an/an/an/an/an/a



The Scripps Research Institute

Curated by ChEMBL


Assay Description
Displacement of [3H]-T0901317 from recombinant human His-SUMO-tagged RORbeta LBD (71 to 459 residues) expressed in Escherichia coli BL21(DE3) at afte...

Bioorg Med Chem Lett 28: 1178-1181 (2018)


Article DOI: 10.1016/j.bmcl.2018.03.001
BindingDB Entry DOI: 10.7270/Q26T0Q9G
More data for this
Ligand-Target Pair
Nuclear receptor ROR-gamma


(Homo sapiens (Human))		BDBM50467007
PNG
(CHEMBL4284441)
Show SMILES COc1ccccc1C(=O)c1sccc1-c1cccc(Cl)c1
Show InChI InChI=1S/C18H13ClO2S/c1-21-16-8-3-2-7-15(16)17(20)18-14(9-10-22-18)12-5-4-6-13(19)11-12/h2-11H,1H3
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n/an/a 780n/an/an/an/an/an/a



The Scripps Research Institute

Curated by ChEMBL


Assay Description
Displacement of [3H]-T0901317 from recombinant human His-SUMO-tagged RORgamma LBD (265 to 518 residues) expressed in Escherichia coli BL21(DE3) after...

Bioorg Med Chem Lett 28: 3210-3215 (2018)


Article DOI: 10.1016/j.bmcl.2018.08.017
BindingDB Entry DOI: 10.7270/Q2KW5JPB
More data for this
Ligand-Target Pair
Nuclear receptor ROR-gamma


(Homo sapiens (Human))		BDBM50466989
PNG
(CHEMBL4288937)
Show SMILES COc1ccccc1C(=O)c1sccc1-c1cccc(c1)C(F)(F)F
Show InChI InChI=1S/C19H13F3O2S/c1-24-16-8-3-2-7-15(16)17(23)18-14(9-10-25-18)12-5-4-6-13(11-12)19(20,21)22/h2-11H,1H3
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n/an/a 790n/an/an/an/an/an/a



The Scripps Research Institute

Curated by ChEMBL


Assay Description
Displacement of [3H]-T0901317 from recombinant human His-SUMO-tagged RORgamma LBD (265 to 518 residues) expressed in Escherichia coli BL21(DE3) after...

Bioorg Med Chem Lett 28: 3210-3215 (2018)


Article DOI: 10.1016/j.bmcl.2018.08.017
BindingDB Entry DOI: 10.7270/Q2KW5JPB
More data for this
Ligand-Target Pair
Nuclear receptor ROR-beta


(Homo sapiens (Human))		BDBM50466995
PNG
(CHEMBL4285720)
Show SMILES Clc1cccc(c1)-c1ncsc1C(=O)c1ccc(Cl)c(Cl)c1
Show InChI InChI=1S/C16H8Cl3NOS/c17-11-3-1-2-9(6-11)14-16(22-8-20-14)15(21)10-4-5-12(18)13(19)7-10/h1-8H
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n/an/a 800n/an/an/an/an/an/a



The Scripps Research Institute

Curated by ChEMBL


Assay Description
Displacement of [3H]-T0901317 from recombinant human His-SUMO-tagged RORbeta LBD (71 to 459 residues) expressed in Escherichia coli BL21(DE3) after 1...

Bioorg Med Chem Lett 28: 3210-3215 (2018)


Article DOI: 10.1016/j.bmcl.2018.08.017
BindingDB Entry DOI: 10.7270/Q2KW5JPB
More data for this
Ligand-Target Pair
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