BindingDB PrimarySearch

Found 26 hits with Last Name = 'chavez-noriega' and Initial = 'le'
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Neuronal acetylcholine receptor subunit alpha-2 (Homo sapiens (Human))	BDBM50049757 (()-2-(6-Chloro-pyridin-3-yl)-7-aza-bicyclo[2.2.1]h...) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid PDB UniChem Patents Similars	PDB PubMed	10.2	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
SIBIA Neurosciences, Inc. Curated by PDSP K_i Database									J Pharmacol Exp Ther 284: 777-89 (1998) BindingDB Entry DOI: 10.7270/Q28G8J7Q
SIBIA Neurosciences, Inc. Curated by PDSP K_i Database					More data for this Ligand-Target Pair				3D Structure (crystal)
Neuronal acetylcholine receptor subunit alpha-4 (Homo sapiens (Human))	BDBM50049757 (()-2-(6-Chloro-pyridin-3-yl)-7-aza-bicyclo[2.2.1]h...) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid PDB UniChem Patents Similars	PubMed	38.3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
SIBIA Neurosciences, Inc. Curated by PDSP K_i Database									J Pharmacol Exp Ther 284: 777-89 (1998) BindingDB Entry DOI: 10.7270/Q28G8J7Q
SIBIA Neurosciences, Inc. Curated by PDSP K_i Database					More data for this Ligand-Target Pair
Neuronal acetylcholine receptor subunit alpha-3 (Homo sapiens (Human))	BDBM50049757 (()-2-(6-Chloro-pyridin-3-yl)-7-aza-bicyclo[2.2.1]h...) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid PDB UniChem Patents Similars	PubMed	151	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
SIBIA Neurosciences, Inc. Curated by PDSP K_i Database									J Pharmacol Exp Ther 284: 777-89 (1998) BindingDB Entry DOI: 10.7270/Q28G8J7Q
SIBIA Neurosciences, Inc. Curated by PDSP K_i Database					More data for this Ligand-Target Pair
Neuronal acetylcholine receptor subunit alpha-4 (Homo sapiens (Human))	BDBM50107863 ((-)-cytisine \| (1R,9R)-7,11-diazatricyclo[7.3.1.0~...) Show SMILES O=c1cccc2[C@H]3CNC[C@@H](C3)Cn12 Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Similars	PubMed	515	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
SIBIA Neurosciences, Inc. Curated by PDSP K_i Database									J Pharmacol Exp Ther 284: 777-89 (1998) BindingDB Entry DOI: 10.7270/Q28G8J7Q
SIBIA Neurosciences, Inc. Curated by PDSP K_i Database					More data for this Ligand-Target Pair
Neuronal acetylcholine receptor subunit alpha-4 (Homo sapiens (Human))	BDBM50061565 ((+)Methyl-(2,3,3-trimethyl-bicyclo[2.2.1]hept-2-yl...) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG PC cid PC sid UniChem Patents Similars	PubMed	560	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
SIBIA Neurosciences, Inc. Curated by PDSP K_i Database									J Pharmacol Exp Ther 284: 777-89 (1998) BindingDB Entry DOI: 10.7270/Q28G8J7Q
SIBIA Neurosciences, Inc. Curated by PDSP K_i Database					More data for this Ligand-Target Pair
Neuronal acetylcholine receptor subunit alpha-3 (Homo sapiens (Human))	BDBM81458 (CAS_57-94-3 \| NSC_6000 \| d-Tubocurarine) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid PDB UniChem Similars	PubMed	730	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
SIBIA Neurosciences, Inc. Curated by PDSP K_i Database									J Pharmacol Exp Ther 284: 777-89 (1998) BindingDB Entry DOI: 10.7270/Q28G8J7Q
SIBIA Neurosciences, Inc. Curated by PDSP K_i Database					More data for this Ligand-Target Pair
Neuronal acetylcholine receptor subunit alpha-4 (Homo sapiens (Human))	BDBM81458 (CAS_57-94-3 \| NSC_6000 \| d-Tubocurarine) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid PDB UniChem Similars	PubMed	860	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
SIBIA Neurosciences, Inc. Curated by PDSP K_i Database									J Pharmacol Exp Ther 284: 777-89 (1998) BindingDB Entry DOI: 10.7270/Q28G8J7Q
SIBIA Neurosciences, Inc. Curated by PDSP K_i Database					More data for this Ligand-Target Pair
Neuronal acetylcholine receptor subunit alpha-4 (Homo sapiens (Human))	BDBM85207 (CAS_123990 \| NSC_123990 \| Suberyldicholine) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase KEGG PC cid PC sid UniChem Patents Similars	PubMed	1.12E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
SIBIA Neurosciences, Inc. Curated by PDSP K_i Database									J Pharmacol Exp Ther 284: 777-89 (1998) BindingDB Entry DOI: 10.7270/Q28G8J7Q
SIBIA Neurosciences, Inc. Curated by PDSP K_i Database					More data for this Ligand-Target Pair
Neuronal acetylcholine receptor subunit alpha-3 (Homo sapiens (Human))	BDBM50061565 ((+)Methyl-(2,3,3-trimethyl-bicyclo[2.2.1]hept-2-yl...) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG PC cid PC sid UniChem Patents Similars	PubMed	1.40E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
SIBIA Neurosciences, Inc. Curated by PDSP K_i Database									J Pharmacol Exp Ther 284: 777-89 (1998) BindingDB Entry DOI: 10.7270/Q28G8J7Q
SIBIA Neurosciences, Inc. Curated by PDSP K_i Database					More data for this Ligand-Target Pair
Neuronal acetylcholine receptor subunit alpha-2 (Homo sapiens (Human))	BDBM81458 (CAS_57-94-3 \| NSC_6000 \| d-Tubocurarine) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid PDB UniChem Similars	PubMed	2.26E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
SIBIA Neurosciences, Inc. Curated by PDSP K_i Database									J Pharmacol Exp Ther 284: 777-89 (1998) BindingDB Entry DOI: 10.7270/Q28G8J7Q
SIBIA Neurosciences, Inc. Curated by PDSP K_i Database					More data for this Ligand-Target Pair
Neuronal acetylcholine receptor subunit alpha-2 (Homo sapiens (Human))	BDBM50061565 ((+)Methyl-(2,3,3-trimethyl-bicyclo[2.2.1]hept-2-yl...) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG PC cid PC sid UniChem Patents Similars	DrugBank PubMed	3.06E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
SIBIA Neurosciences, Inc. Curated by PDSP K_i Database									J Pharmacol Exp Ther 284: 777-89 (1998) BindingDB Entry DOI: 10.7270/Q28G8J7Q
SIBIA Neurosciences, Inc. Curated by PDSP K_i Database					More data for this Ligand-Target Pair
Neuronal acetylcholine receptor subunit alpha-2 (Homo sapiens (Human))	BDBM50061562 ((12R,13aR)-12-Methoxy-1,4,5,6,9,11,12,13-octahydro...) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	PubMed	5.09E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
SIBIA Neurosciences, Inc. Curated by PDSP K_i Database									J Pharmacol Exp Ther 284: 777-89 (1998) BindingDB Entry DOI: 10.7270/Q28G8J7Q
SIBIA Neurosciences, Inc. Curated by PDSP K_i Database					More data for this Ligand-Target Pair
Neuronal acetylcholine receptor subunit alpha-4 (Homo sapiens (Human))	BDBM50004108 ((+-)-nicotine \| (R,S)-nicotine \| (RS)-nicotine \| 3...) Show SMILES CN1CCCC1c1cccnc1 Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank KEGG PC cid PC sid PDB UniChem Patents Similars	DrugBank PDB PubMed	6.69E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
SIBIA Neurosciences, Inc. Curated by PDSP K_i Database									J Pharmacol Exp Ther 284: 777-89 (1998) BindingDB Entry DOI: 10.7270/Q28G8J7Q
SIBIA Neurosciences, Inc. Curated by PDSP K_i Database					More data for this Ligand-Target Pair				3D Structure (crystal)
Neuronal acetylcholine receptor subunit alpha-2 (Homo sapiens (Human))	BDBM85207 (CAS_123990 \| NSC_123990 \| Suberyldicholine) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase KEGG PC cid PC sid UniChem Patents Similars	PubMed	8.75E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
SIBIA Neurosciences, Inc. Curated by PDSP K_i Database									J Pharmacol Exp Ther 284: 777-89 (1998) BindingDB Entry DOI: 10.7270/Q28G8J7Q
SIBIA Neurosciences, Inc. Curated by PDSP K_i Database					More data for this Ligand-Target Pair
Neuronal acetylcholine receptor subunit alpha-2 (Homo sapiens (Human))	BDBM50004108 ((+-)-nicotine \| (R,S)-nicotine \| (RS)-nicotine \| 3...) Show SMILES CN1CCCC1c1cccnc1 Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank KEGG PC cid PC sid PDB UniChem Patents Similars	DrugBank PubMed	9.90E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
SIBIA Neurosciences, Inc. Curated by PDSP K_i Database									J Pharmacol Exp Ther 284: 777-89 (1998) BindingDB Entry DOI: 10.7270/Q28G8J7Q
SIBIA Neurosciences, Inc. Curated by PDSP K_i Database					More data for this Ligand-Target Pair
Neuronal acetylcholine receptor subunit alpha-4 (Homo sapiens (Human))	BDBM50061567 (1,1-Dimethyl-4-phenyl-piperazin-1-ium \| CHEMBL1347...) Show SMILES C[N+]1(C)CCN(CC1)c1ccccc1 Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE KEGG PC cid PC sid UniChem Patents Similars	PubMed	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
SIBIA Neurosciences, Inc. Curated by PDSP K_i Database									J Pharmacol Exp Ther 284: 777-89 (1998) BindingDB Entry DOI: 10.7270/Q28G8J7Q
SIBIA Neurosciences, Inc. Curated by PDSP K_i Database					More data for this Ligand-Target Pair
Neuronal acetylcholine receptor subunit alpha-4 (Homo sapiens (Human))	BDBM50061562 ((12R,13aR)-12-Methoxy-1,4,5,6,9,11,12,13-octahydro...) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	PubMed	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
SIBIA Neurosciences, Inc. Curated by PDSP K_i Database									J Pharmacol Exp Ther 284: 777-89 (1998) BindingDB Entry DOI: 10.7270/Q28G8J7Q
SIBIA Neurosciences, Inc. Curated by PDSP K_i Database					More data for this Ligand-Target Pair
Neuronal acetylcholine receptor subunit alpha-3 (Homo sapiens (Human))	BDBM85207 (CAS_123990 \| NSC_123990 \| Suberyldicholine) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase KEGG PC cid PC sid UniChem Patents Similars	PubMed	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
SIBIA Neurosciences, Inc. Curated by PDSP K_i Database									J Pharmacol Exp Ther 284: 777-89 (1998) BindingDB Entry DOI: 10.7270/Q28G8J7Q
SIBIA Neurosciences, Inc. Curated by PDSP K_i Database					More data for this Ligand-Target Pair
Neuronal acetylcholine receptor subunit alpha-3 (Homo sapiens (Human))	BDBM50004108 ((+-)-nicotine \| (R,S)-nicotine \| (RS)-nicotine \| 3...) Show SMILES CN1CCCC1c1cccnc1 Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank KEGG PC cid PC sid PDB UniChem Patents Similars	PubMed	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
SIBIA Neurosciences, Inc. Curated by PDSP K_i Database									J Pharmacol Exp Ther 284: 777-89 (1998) BindingDB Entry DOI: 10.7270/Q28G8J7Q
SIBIA Neurosciences, Inc. Curated by PDSP K_i Database					More data for this Ligand-Target Pair
Neuronal acetylcholine receptor subunit alpha-3 (Homo sapiens (Human))	BDBM50061567 (1,1-Dimethyl-4-phenyl-piperazin-1-ium \| CHEMBL1347...) Show SMILES C[N+]1(C)CCN(CC1)c1ccccc1 Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE KEGG PC cid PC sid UniChem Patents Similars	PubMed	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
SIBIA Neurosciences, Inc. Curated by PDSP K_i Database									J Pharmacol Exp Ther 284: 777-89 (1998) BindingDB Entry DOI: 10.7270/Q28G8J7Q
SIBIA Neurosciences, Inc. Curated by PDSP K_i Database					More data for this Ligand-Target Pair
Neuronal acetylcholine receptor subunit alpha-3 (Homo sapiens (Human))	BDBM50107863 ((-)-cytisine \| (1R,9R)-7,11-diazatricyclo[7.3.1.0~...) Show SMILES O=c1cccc2[C@H]3CNC[C@@H](C3)Cn12 Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Similars	PubMed	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
SIBIA Neurosciences, Inc. Curated by PDSP K_i Database									J Pharmacol Exp Ther 284: 777-89 (1998) BindingDB Entry DOI: 10.7270/Q28G8J7Q
SIBIA Neurosciences, Inc. Curated by PDSP K_i Database					More data for this Ligand-Target Pair
Neuronal acetylcholine receptor subunit alpha-3 (Homo sapiens (Human))	BDBM50061562 ((12R,13aR)-12-Methoxy-1,4,5,6,9,11,12,13-octahydro...) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	PubMed	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
SIBIA Neurosciences, Inc. Curated by PDSP K_i Database									J Pharmacol Exp Ther 284: 777-89 (1998) BindingDB Entry DOI: 10.7270/Q28G8J7Q
SIBIA Neurosciences, Inc. Curated by PDSP K_i Database					More data for this Ligand-Target Pair
Neuronal acetylcholine receptor subunit alpha-2 (Homo sapiens (Human))	BDBM50061567 (1,1-Dimethyl-4-phenyl-piperazin-1-ium \| CHEMBL1347...) Show SMILES C[N+]1(C)CCN(CC1)c1ccccc1 Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE KEGG PC cid PC sid UniChem Patents Similars	PubMed	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
SIBIA Neurosciences, Inc. Curated by PDSP K_i Database									J Pharmacol Exp Ther 284: 777-89 (1998) BindingDB Entry DOI: 10.7270/Q28G8J7Q
SIBIA Neurosciences, Inc. Curated by PDSP K_i Database					More data for this Ligand-Target Pair
Neuronal acetylcholine receptor; alpha2/beta4 (Homo sapiens (Human))	BDBM50071366 (7-Methoxy-2,3,3a,4,5,9b-hexahydro-1H-pyrrolo[3,2-h...) Show SMILES COc1cc2CCC3CCNC3c2cn1 Show InChI	PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	PubMed	n/a	n/a	n/a	n/a	8.70E+4	n/a	n/a	n/a	n/a
SIBIA Neurosciences Inc. Curated by ChEMBL					Assay Description Compound was evaluated for agonist activity against activated human recombinant Nicotinic acetylcholine receptor alpha2-beta4 in Xenopus Oocytes				Bioorg Med Chem Lett 8: 2173-8 (1999) BindingDB Entry DOI: 10.7270/Q2V9877J
SIBIA Neurosciences Inc. Curated by ChEMBL					More data for this Ligand-Target Pair
Neuronal acetylcholine receptor subunit alpha-4/beta-4 (Homo sapiens (Human))	BDBM50071366 (7-Methoxy-2,3,3a,4,5,9b-hexahydro-1H-pyrrolo[3,2-h...) Show SMILES COc1cc2CCC3CCNC3c2cn1 Show InChI	PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	PubMed	n/a	n/a	n/a	n/a	3.20E+4	n/a	n/a	n/a	n/a
SIBIA Neurosciences Inc. Curated by ChEMBL					Assay Description Compound was evaluated for its agonist activity against activated human recombinant Nicotinic acetylcholine receptor alpha4-beta4 in Xenopus Oocytes				Bioorg Med Chem Lett 8: 2173-8 (1999) BindingDB Entry DOI: 10.7270/Q2V9877J
SIBIA Neurosciences Inc. Curated by ChEMBL					More data for this Ligand-Target Pair
Neuronal acetylcholine receptor subunit alpha-4/beta-2 (Homo sapiens (Human))	BDBM50071366 (7-Methoxy-2,3,3a,4,5,9b-hexahydro-1H-pyrrolo[3,2-h...) Show SMILES COc1cc2CCC3CCNC3c2cn1 Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	PubMed	n/a	n/a	n/a	n/a	3.00E+3	n/a	n/a	n/a	n/a
SIBIA Neurosciences Inc. Curated by ChEMBL					Assay Description Compound was evaluated for agonist activity against activated human recombinant aNicotinic acetylcholine receptor alpha4-beta2 in Xenopus Oocytes				Bioorg Med Chem Lett 8: 2173-8 (1999) BindingDB Entry DOI: 10.7270/Q2V9877J
SIBIA Neurosciences Inc. Curated by ChEMBL					More data for this Ligand-Target Pair