Found 50 hits with Last Name = 'choi' and Initial = 'ys' Target/Host
(Institution) | Ligand | Target/Host
Links | Ligand
Links | Trg + Lig
Links | Ki
nM | ΔG°
kJ/mole | IC50
nM | Kd
nM | EC50/IC50
nM | koff
s-1 | kon
M-1s-1 | pH | Temp
°C |
|---|
Transient receptor potential cation channel subfamily V member 1
(Rattus norvegicus (rat)) | BDBM20330
(3-[(4-tert-butylphenyl)methyl]-1-[(4-methanesulfon...)Show SMILES COc1cc(CNC(=S)NCc2ccc(cc2)C(C)(C)C)ccc1NS(C)(=O)=O Show InChI InChI=1S/C21H29N3O3S2/c1-21(2,3)17-9-6-15(7-10-17)13-22-20(28)23-14-16-8-11-18(19(12-16)27-4)24-29(5,25)26/h6-12,24H,13-14H2,1-5H3,(H2,22,23,28) | PDB
MMDB
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PubMed
| 3.40 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Seoul National University
Curated by ChEMBL
| Assay Description
Antagonist activity towards rat TRPV1 expressed in CHO cells |
Bioorg Med Chem Lett 15: 4143-50 (2005)
Article DOI: 10.1016/j.bmcl.2005.06.006
BindingDB Entry DOI: 10.7270/Q2JH3KQB |
More data for this
Ligand-Target Pair | |
Transient receptor potential cation channel subfamily V member 1
(Rattus norvegicus (rat)) | BDBM20321
(3-[(4-tert-butylphenyl)methyl]-1-[(3-fluoro-4-meth...)Show SMILES CC(C)(C)c1ccc(CNC(=S)NCc2ccc(NS(C)(=O)=O)c(F)c2)cc1 Show InChI InChI=1S/C20H26FN3O2S2/c1-20(2,3)16-8-5-14(6-9-16)12-22-19(27)23-13-15-7-10-18(17(21)11-15)24-28(4,25)26/h5-11,24H,12-13H2,1-4H3,(H2,22,23,27) | PDB
MMDB
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PubMed
| 9.16 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Seoul National University
Curated by ChEMBL
| Assay Description
Antagonist activity towards rat TRPV1 expressed in CHO cells |
Bioorg Med Chem Lett 15: 4143-50 (2005)
Article DOI: 10.1016/j.bmcl.2005.06.006
BindingDB Entry DOI: 10.7270/Q2JH3KQB |
More data for this
Ligand-Target Pair | |
Transient receptor potential cation channel subfamily V member 1
(Rattus norvegicus (rat)) | BDBM20330
(3-[(4-tert-butylphenyl)methyl]-1-[(4-methanesulfon...)Show SMILES COc1cc(CNC(=S)NCc2ccc(cc2)C(C)(C)C)ccc1NS(C)(=O)=O Show InChI InChI=1S/C21H29N3O3S2/c1-21(2,3)17-9-6-15(7-10-17)13-22-20(28)23-14-16-8-11-18(19(12-16)27-4)24-29(5,25)26/h6-12,24H,13-14H2,1-5H3,(H2,22,23,28) | PDB
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| 50.4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Seoul National University
Curated by ChEMBL
| Assay Description
In vitro inhibition of [3H]-RTX binding to rat TRPV1 expressed in CHO cells |
Bioorg Med Chem Lett 15: 4143-50 (2005)
Article DOI: 10.1016/j.bmcl.2005.06.006
BindingDB Entry DOI: 10.7270/Q2JH3KQB |
More data for this
Ligand-Target Pair | |
Transient receptor potential cation channel subfamily V member 1
(Rattus norvegicus (rat)) | BDBM20321
(3-[(4-tert-butylphenyl)methyl]-1-[(3-fluoro-4-meth...)Show SMILES CC(C)(C)c1ccc(CNC(=S)NCc2ccc(NS(C)(=O)=O)c(F)c2)cc1 Show InChI InChI=1S/C20H26FN3O2S2/c1-20(2,3)16-8-5-14(6-9-16)12-22-19(27)23-13-15-7-10-18(17(21)11-15)24-28(4,25)26/h5-11,24H,12-13H2,1-4H3,(H2,22,23,27) | PDB
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| 53.5 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Seoul National University
Curated by ChEMBL
| Assay Description
In vitro inhibition of [3H]-RTX binding to rat TRPV1 expressed in CHO cells |
Bioorg Med Chem Lett 15: 4143-50 (2005)
Article DOI: 10.1016/j.bmcl.2005.06.006
BindingDB Entry DOI: 10.7270/Q2JH3KQB |
More data for this
Ligand-Target Pair | |
Transient receptor potential cation channel subfamily V member 1
(Rattus norvegicus (rat)) | BDBM20315
(3-[(4-tert-butylphenyl)methyl]-1-[(4-methanesulfon...)Show SMILES CC(C)(C)c1ccc(CNC(=S)NCc2ccc(NS(C)(=O)=O)cc2)cc1 Show InChI InChI=1S/C20H27N3O2S2/c1-20(2,3)17-9-5-15(6-10-17)13-21-19(26)22-14-16-7-11-18(12-8-16)23-27(4,24)25/h5-12,23H,13-14H2,1-4H3,(H2,21,22,26) | PDB
MMDB
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UniChem
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PubMed
| 54 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Seoul National University
Curated by ChEMBL
| Assay Description
Antagonist activity towards rat TRPV1 expressed in CHO cells |
Bioorg Med Chem Lett 15: 4143-50 (2005)
Article DOI: 10.1016/j.bmcl.2005.06.006
BindingDB Entry DOI: 10.7270/Q2JH3KQB |
More data for this
Ligand-Target Pair | |
Transient receptor potential cation channel subfamily V member 1
(Rattus norvegicus (rat)) | BDBM20315
(3-[(4-tert-butylphenyl)methyl]-1-[(4-methanesulfon...)Show SMILES CC(C)(C)c1ccc(CNC(=S)NCc2ccc(NS(C)(=O)=O)cc2)cc1 Show InChI InChI=1S/C20H27N3O2S2/c1-20(2,3)17-9-5-15(6-10-17)13-21-19(26)22-14-16-7-11-18(12-8-16)23-27(4,24)25/h5-12,23H,13-14H2,1-4H3,(H2,21,22,26) | PDB
MMDB
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PC sid
UniChem
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| Article
PubMed
| 63 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Seoul National University
Curated by ChEMBL
| Assay Description
In vitro inhibition of [3H]-RTX binding to rat TRPV1 expressed in CHO cells |
Bioorg Med Chem Lett 15: 4143-50 (2005)
Article DOI: 10.1016/j.bmcl.2005.06.006
BindingDB Entry DOI: 10.7270/Q2JH3KQB |
More data for this
Ligand-Target Pair | |
Transient receptor potential cation channel subfamily V member 1
(Rattus norvegicus (rat)) | BDBM50169732
((4-tert-Butyl-benzyl)-thiocarbamic acid 4-methanes...)Show SMILES COc1cc(COC(=S)NCc2ccc(cc2)C(C)(C)C)ccc1NS(C)(=O)=O Show InChI InChI=1S/C21H28N2O4S2/c1-21(2,3)17-9-6-15(7-10-17)13-22-20(28)27-14-16-8-11-18(19(12-16)26-4)23-29(5,24)25/h6-12,23H,13-14H2,1-5H3,(H,22,28) | PDB
MMDB
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KEGG
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| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 110 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Seoul National University
Curated by ChEMBL
| Assay Description
Antagonist activity towards rat TRPV1 expressed in CHO cells |
Bioorg Med Chem Lett 15: 4143-50 (2005)
Article DOI: 10.1016/j.bmcl.2005.06.006
BindingDB Entry DOI: 10.7270/Q2JH3KQB |
More data for this
Ligand-Target Pair | |
Transient receptor potential cation channel subfamily V member 1
(Rattus norvegicus (rat)) | BDBM50169728
(CHEMBL364193 | N-(4-tert-Butyl-benzyl)-2-(3-fluoro...)Show SMILES CC(C)(C)c1ccc(CNC(=O)Cc2ccc(NS(C)(=O)=O)c(F)c2)cc1 Show InChI InChI=1S/C20H25FN2O3S/c1-20(2,3)16-8-5-14(6-9-16)13-22-19(24)12-15-7-10-18(17(21)11-15)23-27(4,25)26/h5-11,23H,12-13H2,1-4H3,(H,22,24) | PDB
MMDB
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KEGG
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| CHEMBL
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PC sid
UniChem
Similars
| Article
PubMed
| 118 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Seoul National University
Curated by ChEMBL
| Assay Description
Antagonist activity towards rat TRPV1 expressed in CHO cells |
Bioorg Med Chem Lett 15: 4143-50 (2005)
Article DOI: 10.1016/j.bmcl.2005.06.006
BindingDB Entry DOI: 10.7270/Q2JH3KQB |
More data for this
Ligand-Target Pair | |
Transient receptor potential cation channel subfamily V member 1
(Rattus norvegicus (rat)) | BDBM50169733
((4-tert-Butyl-benzyl)-thiocarbamic acid 3-fluoro-4...)Show SMILES CC(C)(C)c1ccc(CNC(=S)OCc2ccc(NS(C)(=O)=O)c(F)c2)cc1 Show InChI InChI=1S/C20H25FN2O3S2/c1-20(2,3)16-8-5-14(6-9-16)12-22-19(27)26-13-15-7-10-18(17(21)11-15)23-28(4,24)25/h5-11,23H,12-13H2,1-4H3,(H,22,27) | PDB
MMDB
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KEGG
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PC sid
UniChem
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| Article
PubMed
| 120 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Seoul National University
Curated by ChEMBL
| Assay Description
Antagonist activity towards rat TRPV1 expressed in CHO cells |
Bioorg Med Chem Lett 15: 4143-50 (2005)
Article DOI: 10.1016/j.bmcl.2005.06.006
BindingDB Entry DOI: 10.7270/Q2JH3KQB |
More data for this
Ligand-Target Pair | |
Transient receptor potential cation channel subfamily V member 1
(Rattus norvegicus (rat)) | BDBM50169735
((4-tert-Butyl-benzyl)-thiocarbamic acid 4-methanes...)Show SMILES CC(C)(C)c1ccc(CNC(=S)OCc2ccc(NS(C)(=O)=O)cc2)cc1 Show InChI InChI=1S/C20H26N2O3S2/c1-20(2,3)17-9-5-15(6-10-17)13-21-19(26)25-14-16-7-11-18(12-8-16)22-27(4,23)24/h5-12,22H,13-14H2,1-4H3,(H,21,26) | PDB
MMDB
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PC sid
UniChem
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PubMed
| 222 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Seoul National University
Curated by ChEMBL
| Assay Description
Antagonist activity towards rat TRPV1 expressed in CHO cells |
Bioorg Med Chem Lett 15: 4143-50 (2005)
Article DOI: 10.1016/j.bmcl.2005.06.006
BindingDB Entry DOI: 10.7270/Q2JH3KQB |
More data for this
Ligand-Target Pair | |
Transient receptor potential cation channel subfamily V member 1
(Rattus norvegicus (rat)) | BDBM50169740
(CHEMBL188602 | N-{4-[3-(4-tert-Butyl-benzyl)-ureid...)Show SMILES CC(C)(C)c1ccc(CNC(=O)NCc2ccc(NS(C)(=O)=O)cc2)cc1 Show InChI InChI=1S/C20H27N3O3S/c1-20(2,3)17-9-5-15(6-10-17)13-21-19(24)22-14-16-7-11-18(12-8-16)23-27(4,25)26/h5-12,23H,13-14H2,1-4H3,(H2,21,22,24) | PDB
MMDB
Reactome pathway
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UniChem
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PubMed
| 225 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Seoul National University
Curated by ChEMBL
| Assay Description
Antagonist activity towards rat TRPV1 expressed in CHO cells |
Bioorg Med Chem Lett 15: 4143-50 (2005)
Article DOI: 10.1016/j.bmcl.2005.06.006
BindingDB Entry DOI: 10.7270/Q2JH3KQB |
More data for this
Ligand-Target Pair | |
Transient receptor potential cation channel subfamily V member 1
(Rattus norvegicus (rat)) | BDBM50169726
(CHEMBL185683 | N-(4-tert-Butyl-benzyl)-2-(4-methan...)Show SMILES CC(C)(C)c1ccc(CNC(=O)Cc2ccc(NS(C)(=O)=O)cc2)cc1 Show InChI InChI=1S/C20H26N2O3S/c1-20(2,3)17-9-5-16(6-10-17)14-21-19(23)13-15-7-11-18(12-8-15)22-26(4,24)25/h5-12,22H,13-14H2,1-4H3,(H,21,23) | PDB
MMDB
Reactome pathway
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PC cid
PC sid
UniChem
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| Article
PubMed
| 398 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Seoul National University
Curated by ChEMBL
| Assay Description
Antagonist activity towards rat TRPV1 expressed in CHO cells |
Bioorg Med Chem Lett 15: 4143-50 (2005)
Article DOI: 10.1016/j.bmcl.2005.06.006
BindingDB Entry DOI: 10.7270/Q2JH3KQB |
More data for this
Ligand-Target Pair | |
Transient receptor potential cation channel subfamily V member 1
(Rattus norvegicus (rat)) | BDBM50169733
((4-tert-Butyl-benzyl)-thiocarbamic acid 3-fluoro-4...)Show SMILES CC(C)(C)c1ccc(CNC(=S)OCc2ccc(NS(C)(=O)=O)c(F)c2)cc1 Show InChI InChI=1S/C20H25FN2O3S2/c1-20(2,3)16-8-5-14(6-9-16)12-22-19(27)26-13-15-7-10-18(17(21)11-15)23-28(4,24)25/h5-11,23H,12-13H2,1-4H3,(H,22,27) | PDB
MMDB
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KEGG
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PC sid
UniChem
Similars
| Article
PubMed
| 450 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Seoul National University
Curated by ChEMBL
| Assay Description
In vitro inhibition of [3H]-RTX binding to rat TRPV1 expressed in CHO cells |
Bioorg Med Chem Lett 15: 4143-50 (2005)
Article DOI: 10.1016/j.bmcl.2005.06.006
BindingDB Entry DOI: 10.7270/Q2JH3KQB |
More data for this
Ligand-Target Pair | |
Transient receptor potential cation channel subfamily V member 1
(Rattus norvegicus (rat)) | BDBM50169732
((4-tert-Butyl-benzyl)-thiocarbamic acid 4-methanes...)Show SMILES COc1cc(COC(=S)NCc2ccc(cc2)C(C)(C)C)ccc1NS(C)(=O)=O Show InChI InChI=1S/C21H28N2O4S2/c1-21(2,3)17-9-6-15(7-10-17)13-22-20(28)27-14-16-8-11-18(19(12-16)26-4)23-29(5,24)25/h6-12,23H,13-14H2,1-5H3,(H,22,28) | PDB
MMDB
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UniChem
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PubMed
| 461 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Seoul National University
Curated by ChEMBL
| Assay Description
In vitro inhibition of [3H]-RTX binding to rat TRPV1 expressed in CHO cells |
Bioorg Med Chem Lett 15: 4143-50 (2005)
Article DOI: 10.1016/j.bmcl.2005.06.006
BindingDB Entry DOI: 10.7270/Q2JH3KQB |
More data for this
Ligand-Target Pair | |
Transient receptor potential cation channel subfamily V member 1
(Rattus norvegicus (rat)) | BDBM50169722
(CHEMBL363105 | N-{(4-tert-butylbenzyl)-N-hydroxyth...)Show SMILES CC(C)(C)c1ccc(CN(O)C(=S)NCc2ccc(NS(C)(=O)=O)cc2)cc1 Show InChI InChI=1S/C20H27N3O3S2/c1-20(2,3)17-9-5-16(6-10-17)14-23(24)19(27)21-13-15-7-11-18(12-8-15)22-28(4,25)26/h5-12,22,24H,13-14H2,1-4H3,(H,21,27) | PDB
MMDB
Reactome pathway
KEGG
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PC sid
UniChem
Patents
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| Article
PubMed
| 470 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Seoul National University
Curated by ChEMBL
| Assay Description
Antagonist activity towards rat TRPV1 expressed in CHO cells |
Bioorg Med Chem Lett 15: 4143-50 (2005)
Article DOI: 10.1016/j.bmcl.2005.06.006
BindingDB Entry DOI: 10.7270/Q2JH3KQB |
More data for this
Ligand-Target Pair | |
Transient receptor potential cation channel subfamily V member 1
(Rattus norvegicus (rat)) | BDBM50169734
(CHEMBL186109 | N-{(4-tert-butylbenzyl)-N'-hydroxyt...)Show SMILES CC(C)(C)c1ccc(CNC(=S)N(O)Cc2ccc(NS(C)(=O)=O)cc2)cc1 Show InChI InChI=1S/C20H27N3O3S2/c1-20(2,3)17-9-5-15(6-10-17)13-21-19(27)23(24)14-16-7-11-18(12-8-16)22-28(4,25)26/h5-12,22,24H,13-14H2,1-4H3,(H,21,27) | PDB
MMDB
Reactome pathway
KEGG
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PC sid
UniChem
Patents
Similars
| Article
PubMed
| 470 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Seoul National University
Curated by ChEMBL
| Assay Description
Antagonist activity towards rat TRPV1 expressed in CHO cells |
Bioorg Med Chem Lett 15: 4143-50 (2005)
Article DOI: 10.1016/j.bmcl.2005.06.006
BindingDB Entry DOI: 10.7270/Q2JH3KQB |
More data for this
Ligand-Target Pair | |
Transient receptor potential cation channel subfamily V member 1
(Rattus norvegicus (rat)) | BDBM50169728
(CHEMBL364193 | N-(4-tert-Butyl-benzyl)-2-(3-fluoro...)Show SMILES CC(C)(C)c1ccc(CNC(=O)Cc2ccc(NS(C)(=O)=O)c(F)c2)cc1 Show InChI InChI=1S/C20H25FN2O3S/c1-20(2,3)16-8-5-14(6-9-16)13-22-19(24)12-15-7-10-18(17(21)11-15)23-27(4,25)26/h5-11,23H,12-13H2,1-4H3,(H,22,24) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
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GoogleScholar
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| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 472 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Seoul National University
Curated by ChEMBL
| Assay Description
In vitro inhibition of [3H]-RTX binding to rat TRPV1 expressed in CHO cells |
Bioorg Med Chem Lett 15: 4143-50 (2005)
Article DOI: 10.1016/j.bmcl.2005.06.006
BindingDB Entry DOI: 10.7270/Q2JH3KQB |
More data for this
Ligand-Target Pair | |
Transient receptor potential cation channel subfamily V member 1
(Rattus norvegicus (rat)) | BDBM20284
(CHEMBL391997 | CPZ | Capsazepine | N-[2-(4-chlorop...)Show InChI InChI=1S/C19H21ClN2O2S/c20-16-5-3-13(4-6-16)7-8-21-19(25)22-9-1-2-14-10-17(23)18(24)11-15(14)12-22/h3-6,10-11,23-24H,1-2,7-9,12H2,(H,21,25) | PDB
MMDB
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CHEMBL
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| PDB
Article
PubMed
| 520 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Seoul National University
Curated by ChEMBL
| Assay Description
Antagonist activity towards rat TRPV1 expressed in CHO cells |
Bioorg Med Chem Lett 15: 4143-50 (2005)
Article DOI: 10.1016/j.bmcl.2005.06.006
BindingDB Entry DOI: 10.7270/Q2JH3KQB |
More data for this
Ligand-Target Pair | 
3D Structure (crystal) |
Transient receptor potential cation channel subfamily V member 1
(Rattus norvegicus (rat)) | BDBM50169717
(CHEMBL427163 | N-{(4-tert-butylbenzyl)-N-hydroxyth...)Show SMILES CC(C)(C)c1ccc(CN(O)C(=S)NCc2ccc(NS(C)(=O)=O)c(Cl)c2)cc1 Show InChI InChI=1S/C20H26ClN3O3S2/c1-20(2,3)16-8-5-14(6-9-16)13-24(25)19(28)22-12-15-7-10-18(17(21)11-15)23-29(4,26)27/h5-11,23,25H,12-13H2,1-4H3,(H,22,28) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 579 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Seoul National University
Curated by ChEMBL
| Assay Description
Antagonist activity towards rat TRPV1 expressed in CHO cells |
Bioorg Med Chem Lett 15: 4143-50 (2005)
Article DOI: 10.1016/j.bmcl.2005.06.006
BindingDB Entry DOI: 10.7270/Q2JH3KQB |
More data for this
Ligand-Target Pair | |
Transient receptor potential cation channel subfamily V member 1
(Rattus norvegicus (rat)) | BDBM50169738
(CHEMBL188472 | N-{(4-tert-butylbenzyl)-N-hydroxyth...)Show SMILES CC(C)(C)c1ccc(CN(O)C(=[SH+])[N-]Cc2ccc(NS(C)(=O)=O)c(c2)[N+]([O-])=O)cc1 Show InChI InChI=1S/C20H26N4O5S2/c1-20(2,3)16-8-5-14(6-9-16)13-23(25)19(30)21-12-15-7-10-17(22-31(4,28)29)18(11-15)24(26)27/h5-11,22,25H,12-13H2,1-4H3,(H,21,30) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 635 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Seoul National University
Curated by ChEMBL
| Assay Description
Antagonist activity towards rat TRPV1 expressed in CHO cells |
Bioorg Med Chem Lett 15: 4143-50 (2005)
Article DOI: 10.1016/j.bmcl.2005.06.006
BindingDB Entry DOI: 10.7270/Q2JH3KQB |
More data for this
Ligand-Target Pair | |
Transient receptor potential cation channel subfamily V member 1
(Rattus norvegicus (rat)) | BDBM50169735
((4-tert-Butyl-benzyl)-thiocarbamic acid 4-methanes...)Show SMILES CC(C)(C)c1ccc(CNC(=S)OCc2ccc(NS(C)(=O)=O)cc2)cc1 Show InChI InChI=1S/C20H26N2O3S2/c1-20(2,3)17-9-5-15(6-10-17)13-21-19(26)25-14-16-7-11-18(12-8-16)22-27(4,23)24/h5-12,22H,13-14H2,1-4H3,(H,21,26) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 772 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Seoul National University
Curated by ChEMBL
| Assay Description
In vitro inhibition of [3H]-RTX binding to rat TRPV1 expressed in CHO cells |
Bioorg Med Chem Lett 15: 4143-50 (2005)
Article DOI: 10.1016/j.bmcl.2005.06.006
BindingDB Entry DOI: 10.7270/Q2JH3KQB |
More data for this
Ligand-Target Pair | |
Transient receptor potential cation channel subfamily V member 1
(Rattus norvegicus (rat)) | BDBM50169727
(CHEMBL187675 | N-{(4-tert-butylbenzyl)-N-hydroxyth...)Show SMILES CC(C)(C)c1ccc(CN(O)C(=S)NCc2ccc(NS(C)(=O)=O)c(F)c2)cc1 Show InChI InChI=1S/C20H26FN3O3S2/c1-20(2,3)16-8-5-14(6-9-16)13-24(25)19(28)22-12-15-7-10-18(17(21)11-15)23-29(4,26)27/h5-11,23,25H,12-13H2,1-4H3,(H,22,28) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| 800 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Seoul National University
Curated by ChEMBL
| Assay Description
In vitro inhibition of [3H]-RTX binding to rat TRPV1 expressed in CHO cells |
Bioorg Med Chem Lett 15: 4143-50 (2005)
Article DOI: 10.1016/j.bmcl.2005.06.006
BindingDB Entry DOI: 10.7270/Q2JH3KQB |
More data for this
Ligand-Target Pair | |
Transient receptor potential cation channel subfamily V member 1
(Rattus norvegicus (rat)) | BDBM50169724
(CHEMBL190293 | N-{(4-tert-butylbenzyl)-N-hydroxyth...)Show SMILES COc1cc(CNC(=S)N(O)Cc2ccc(cc2)C(C)(C)C)ccc1NS(C)(=O)=O Show InChI InChI=1S/C21H29N3O4S2/c1-21(2,3)17-9-6-15(7-10-17)14-24(25)20(29)22-13-16-8-11-18(19(12-16)28-4)23-30(5,26)27/h6-12,23,25H,13-14H2,1-5H3,(H,22,29) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| 926 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Seoul National University
Curated by ChEMBL
| Assay Description
In vitro inhibition of [3H]-RTX binding to rat TRPV1 expressed in CHO cells |
Bioorg Med Chem Lett 15: 4143-50 (2005)
Article DOI: 10.1016/j.bmcl.2005.06.006
BindingDB Entry DOI: 10.7270/Q2JH3KQB |
More data for this
Ligand-Target Pair | |
Transient receptor potential cation channel subfamily V member 1
(Rattus norvegicus (rat)) | BDBM50169722
(CHEMBL363105 | N-{(4-tert-butylbenzyl)-N-hydroxyth...)Show SMILES CC(C)(C)c1ccc(CN(O)C(=S)NCc2ccc(NS(C)(=O)=O)cc2)cc1 Show InChI InChI=1S/C20H27N3O3S2/c1-20(2,3)17-9-5-16(6-10-17)14-23(24)19(27)21-13-15-7-11-18(12-8-15)22-28(4,25)26/h5-12,22,24H,13-14H2,1-4H3,(H,21,27) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| 1.09E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Seoul National University
Curated by ChEMBL
| Assay Description
In vitro inhibition of [3H]-RTX binding to rat TRPV1 expressed in CHO cells |
Bioorg Med Chem Lett 15: 4143-50 (2005)
Article DOI: 10.1016/j.bmcl.2005.06.006
BindingDB Entry DOI: 10.7270/Q2JH3KQB |
More data for this
Ligand-Target Pair | |
Transient receptor potential cation channel subfamily V member 1
(Rattus norvegicus (rat)) | BDBM20284
(CHEMBL391997 | CPZ | Capsazepine | N-[2-(4-chlorop...)Show InChI InChI=1S/C19H21ClN2O2S/c20-16-5-3-13(4-6-16)7-8-21-19(25)22-9-1-2-14-10-17(23)18(24)11-15(14)12-22/h3-6,10-11,23-24H,1-2,7-9,12H2,(H,21,25) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| Purchase
CHEMBL
MCE
PC cid
PC sid
PDB
UniChem
Patents
Similars
| PDB
Article
PubMed
| 1.30E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Seoul National University
Curated by ChEMBL
| Assay Description
In vitro inhibition of [3H]-RTX binding to rat TRPV1 expressed in CHO cells |
Bioorg Med Chem Lett 15: 4143-50 (2005)
Article DOI: 10.1016/j.bmcl.2005.06.006
BindingDB Entry DOI: 10.7270/Q2JH3KQB |
More data for this
Ligand-Target Pair |
3D Structure (crystal) |
Transient receptor potential cation channel subfamily V member 1
(Rattus norvegicus (rat)) | BDBM50169717
(CHEMBL427163 | N-{(4-tert-butylbenzyl)-N-hydroxyth...)Show SMILES CC(C)(C)c1ccc(CN(O)C(=S)NCc2ccc(NS(C)(=O)=O)c(Cl)c2)cc1 Show InChI InChI=1S/C20H26ClN3O3S2/c1-20(2,3)16-8-5-14(6-9-16)13-24(25)19(28)22-12-15-7-10-18(17(21)11-15)23-29(4,26)27/h5-11,23,25H,12-13H2,1-4H3,(H,22,28) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 1.31E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Seoul National University
Curated by ChEMBL
| Assay Description
In vitro inhibition of [3H]-RTX binding to rat TRPV1 expressed in CHO cells |
Bioorg Med Chem Lett 15: 4143-50 (2005)
Article DOI: 10.1016/j.bmcl.2005.06.006
BindingDB Entry DOI: 10.7270/Q2JH3KQB |
More data for this
Ligand-Target Pair | |
Transient receptor potential cation channel subfamily V member 1
(Rattus norvegicus (rat)) | BDBM50169738
(CHEMBL188472 | N-{(4-tert-butylbenzyl)-N-hydroxyth...)Show SMILES CC(C)(C)c1ccc(CN(O)C(=[SH+])[N-]Cc2ccc(NS(C)(=O)=O)c(c2)[N+]([O-])=O)cc1 Show InChI InChI=1S/C20H26N4O5S2/c1-20(2,3)16-8-5-14(6-9-16)13-23(25)19(30)21-12-15-7-10-17(22-31(4,28)29)18(11-15)24(26)27/h5-11,22,25H,12-13H2,1-4H3,(H,21,30) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 1.33E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Seoul National University
Curated by ChEMBL
| Assay Description
In vitro inhibition of [3H]-RTX binding to rat TRPV1 expressed in CHO cells |
Bioorg Med Chem Lett 15: 4143-50 (2005)
Article DOI: 10.1016/j.bmcl.2005.06.006
BindingDB Entry DOI: 10.7270/Q2JH3KQB |
More data for this
Ligand-Target Pair | |
Transient receptor potential cation channel subfamily V member 1
(Rattus norvegicus (rat)) | BDBM50169719
(CHEMBL186221 | N-(4-tert-butylbenzyl)-2-{4-[(methy...)Show SMILES CC(C)(C)c1ccc(CNC(=S)NNc2ccc(NS(C)(=O)=O)cc2)cc1 Show InChI InChI=1S/C19H26N4O2S2/c1-19(2,3)15-7-5-14(6-8-15)13-20-18(26)22-21-16-9-11-17(12-10-16)23-27(4,24)25/h5-12,21,23H,13H2,1-4H3,(H2,20,22,26) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 1.46E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Seoul National University
Curated by ChEMBL
| Assay Description
Antagonist activity towards rat TRPV1 expressed in CHO cells |
Bioorg Med Chem Lett 15: 4143-50 (2005)
Article DOI: 10.1016/j.bmcl.2005.06.006
BindingDB Entry DOI: 10.7270/Q2JH3KQB |
More data for this
Ligand-Target Pair | |
Transient receptor potential cation channel subfamily V member 1
(Rattus norvegicus (rat)) | BDBM50169730
(CHEMBL362112 | N-{4-[(methylsulfonyl)amino]benzyl}...)Show SMILES CC(C)(C)c1ccc(NNC(=S)NCc2ccc(NS(C)(=O)=O)cc2)cc1 Show InChI InChI=1S/C19H26N4O2S2/c1-19(2,3)15-7-11-16(12-8-15)21-22-18(26)20-13-14-5-9-17(10-6-14)23-27(4,24)25/h5-12,21,23H,13H2,1-4H3,(H2,20,22,26) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 2.01E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Seoul National University
Curated by ChEMBL
| Assay Description
Antagonist activity towards rat TRPV1 expressed in CHO cells |
Bioorg Med Chem Lett 15: 4143-50 (2005)
Article DOI: 10.1016/j.bmcl.2005.06.006
BindingDB Entry DOI: 10.7270/Q2JH3KQB |
More data for this
Ligand-Target Pair | |
Transient receptor potential cation channel subfamily V member 1
(Rattus norvegicus (rat)) | BDBM50169726
(CHEMBL185683 | N-(4-tert-Butyl-benzyl)-2-(4-methan...)Show SMILES CC(C)(C)c1ccc(CNC(=O)Cc2ccc(NS(C)(=O)=O)cc2)cc1 Show InChI InChI=1S/C20H26N2O3S/c1-20(2,3)17-9-5-16(6-10-17)14-21-19(23)13-15-7-11-18(12-8-15)22-26(4,24)25/h5-12,22H,13-14H2,1-4H3,(H,21,23) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| 2.10E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Seoul National University
Curated by ChEMBL
| Assay Description
In vitro inhibition of [3H]-RTX binding to rat TRPV1 expressed in CHO cells |
Bioorg Med Chem Lett 15: 4143-50 (2005)
Article DOI: 10.1016/j.bmcl.2005.06.006
BindingDB Entry DOI: 10.7270/Q2JH3KQB |
More data for this
Ligand-Target Pair | |
Transient receptor potential cation channel subfamily V member 1
(Rattus norvegicus (rat)) | BDBM50169718
((4-Methanesulfonylamino-3-methoxy-benzyl)-thiocarb...)Show SMILES COc1cc(CNC(=S)OCc2ccc(cc2)C(C)(C)C)ccc1NS(C)(=O)=O Show InChI InChI=1S/C21H28N2O4S2/c1-21(2,3)17-9-6-15(7-10-17)14-27-20(28)22-13-16-8-11-18(19(12-16)26-4)23-29(5,24)25/h6-12,23H,13-14H2,1-5H3,(H,22,28) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 2.17E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Seoul National University
Curated by ChEMBL
| Assay Description
In vitro inhibition of [3H]-RTX binding to rat TRPV1 expressed in CHO cells |
Bioorg Med Chem Lett 15: 4143-50 (2005)
Article DOI: 10.1016/j.bmcl.2005.06.006
BindingDB Entry DOI: 10.7270/Q2JH3KQB |
More data for this
Ligand-Target Pair | |
Transient receptor potential cation channel subfamily V member 1
(Rattus norvegicus (rat)) | BDBM50169721
(CHEMBL363244 | N-{(4-tert-butylbenzyl)-N-hydroxyth...)Show SMILES CC(C)(C)c1ccc(CN(O)C(=S)NCc2ccc(NS(C)(=O)=O)cc2Cl)cc1 Show InChI InChI=1S/C20H26ClN3O3S2/c1-20(2,3)16-8-5-14(6-9-16)13-24(25)19(28)22-12-15-7-10-17(11-18(15)21)23-29(4,26)27/h5-11,23,25H,12-13H2,1-4H3,(H,22,28) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 2.27E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Seoul National University
Curated by ChEMBL
| Assay Description
In vitro inhibition of [3H]-RTX binding to rat TRPV1 expressed in CHO cells |
Bioorg Med Chem Lett 15: 4143-50 (2005)
Article DOI: 10.1016/j.bmcl.2005.06.006
BindingDB Entry DOI: 10.7270/Q2JH3KQB |
More data for this
Ligand-Target Pair | |
Transient receptor potential cation channel subfamily V member 1
(Rattus norvegicus (rat)) | BDBM50169740
(CHEMBL188602 | N-{4-[3-(4-tert-Butyl-benzyl)-ureid...)Show SMILES CC(C)(C)c1ccc(CNC(=O)NCc2ccc(NS(C)(=O)=O)cc2)cc1 Show InChI InChI=1S/C20H27N3O3S/c1-20(2,3)17-9-5-15(6-10-17)13-21-19(24)22-14-16-7-11-18(12-8-16)23-27(4,25)26/h5-12,23H,13-14H2,1-4H3,(H2,21,22,24) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| 2.56E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Seoul National University
Curated by ChEMBL
| Assay Description
In vitro inhibition of [3H]-RTX binding to rat TRPV1 expressed in CHO cells |
Bioorg Med Chem Lett 15: 4143-50 (2005)
Article DOI: 10.1016/j.bmcl.2005.06.006
BindingDB Entry DOI: 10.7270/Q2JH3KQB |
More data for this
Ligand-Target Pair | |
Transient receptor potential cation channel subfamily V member 1
(Rattus norvegicus (rat)) | BDBM50169731
(CHEMBL188045 | N-[3-(3,4-Dimethyl-phenyl)-propyl]-...)Show SMILES Cc1ccc(CCCNC(=O)Cc2ccc(NS(C)(=O)=O)c(F)c2)cc1C Show InChI InChI=1S/C20H25FN2O3S/c1-14-6-7-16(11-15(14)2)5-4-10-22-20(24)13-17-8-9-19(18(21)12-17)23-27(3,25)26/h6-9,11-12,23H,4-5,10,13H2,1-3H3,(H,22,24) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 2.71E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Seoul National University
Curated by ChEMBL
| Assay Description
In vitro inhibition of [3H]-RTX binding to rat TRPV1 expressed in CHO cells |
Bioorg Med Chem Lett 15: 4143-50 (2005)
Article DOI: 10.1016/j.bmcl.2005.06.006
BindingDB Entry DOI: 10.7270/Q2JH3KQB |
More data for this
Ligand-Target Pair | |
Transient receptor potential cation channel subfamily V member 1
(Rattus norvegicus (rat)) | BDBM50169723
(CHEMBL186886 | N-{(4-tert-butylbenzyl)-N'-hydroxyu...)Show SMILES CC(C)(C)c1ccc(CNC(=O)N(O)Cc2ccc(NS(C)(=O)=O)cc2)cc1 Show InChI InChI=1S/C20H27N3O4S/c1-20(2,3)17-9-5-15(6-10-17)13-21-19(24)23(25)14-16-7-11-18(12-8-16)22-28(4,26)27/h5-12,22,25H,13-14H2,1-4H3,(H,21,24) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| 3.50E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Seoul National University
Curated by ChEMBL
| Assay Description
In vitro inhibition of [3H]-RTX binding to rat TRPV1 expressed in CHO cells |
Bioorg Med Chem Lett 15: 4143-50 (2005)
Article DOI: 10.1016/j.bmcl.2005.06.006
BindingDB Entry DOI: 10.7270/Q2JH3KQB |
More data for this
Ligand-Target Pair | |
Transient receptor potential cation channel subfamily V member 1
(Rattus norvegicus (rat)) | BDBM50169734
(CHEMBL186109 | N-{(4-tert-butylbenzyl)-N'-hydroxyt...)Show SMILES CC(C)(C)c1ccc(CNC(=S)N(O)Cc2ccc(NS(C)(=O)=O)cc2)cc1 Show InChI InChI=1S/C20H27N3O3S2/c1-20(2,3)17-9-5-15(6-10-17)13-21-19(27)23(24)14-16-7-11-18(12-8-16)22-28(4,25)26/h5-12,22,24H,13-14H2,1-4H3,(H,21,27) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| 4.26E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Seoul National University
Curated by ChEMBL
| Assay Description
In vitro inhibition of [3H]-RTX binding to rat TRPV1 expressed in CHO cells |
Bioorg Med Chem Lett 15: 4143-50 (2005)
Article DOI: 10.1016/j.bmcl.2005.06.006
BindingDB Entry DOI: 10.7270/Q2JH3KQB |
More data for this
Ligand-Target Pair | |
Transient receptor potential cation channel subfamily V member 1
(Rattus norvegicus (rat)) | BDBM50169737
((4-Methanesulfonylamino-benzyl)-thiocarbamic acid ...)Show SMILES CC(C)(C)c1ccc(COC(=S)NCc2ccc(NS(C)(=O)=O)cc2)cc1 Show InChI InChI=1S/C20H26N2O3S2/c1-20(2,3)17-9-5-16(6-10-17)14-25-19(26)21-13-15-7-11-18(12-8-15)22-27(4,23)24/h5-12,22H,13-14H2,1-4H3,(H,21,26) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 4.60E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Seoul National University
Curated by ChEMBL
| Assay Description
In vitro inhibition of [3H]-RTX binding to rat TRPV1 expressed in CHO cells |
Bioorg Med Chem Lett 15: 4143-50 (2005)
Article DOI: 10.1016/j.bmcl.2005.06.006
BindingDB Entry DOI: 10.7270/Q2JH3KQB |
More data for this
Ligand-Target Pair | |
Transient receptor potential cation channel subfamily V member 1
(Rattus norvegicus (rat)) | BDBM50169731
(CHEMBL188045 | N-[3-(3,4-Dimethyl-phenyl)-propyl]-...)Show SMILES Cc1ccc(CCCNC(=O)Cc2ccc(NS(C)(=O)=O)c(F)c2)cc1C Show InChI InChI=1S/C20H25FN2O3S/c1-14-6-7-16(11-15(14)2)5-4-10-22-20(24)13-17-8-9-19(18(21)12-17)23-27(3,25)26/h6-9,11-12,23H,4-5,10,13H2,1-3H3,(H,22,24) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 4.66E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Seoul National University
Curated by ChEMBL
| Assay Description
Antagonist activity towards rat TRPV1 expressed in CHO cells |
Bioorg Med Chem Lett 15: 4143-50 (2005)
Article DOI: 10.1016/j.bmcl.2005.06.006
BindingDB Entry DOI: 10.7270/Q2JH3KQB |
More data for this
Ligand-Target Pair | |
Transient receptor potential cation channel subfamily V member 1
(Rattus norvegicus (rat)) | BDBM50169725
(2-(4-tert-Butyl-phenyl)-N-(4-methanesulfonylamino-...)Show SMILES CC(C)(C)c1ccc(CC(=O)NCc2ccc(NS(C)(=O)=O)cc2)cc1 Show InChI InChI=1S/C20H26N2O3S/c1-20(2,3)17-9-5-15(6-10-17)13-19(23)21-14-16-7-11-18(12-8-16)22-26(4,24)25/h5-12,22H,13-14H2,1-4H3,(H,21,23) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 5.22E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Seoul National University
Curated by ChEMBL
| Assay Description
In vitro inhibition of [3H]-RTX binding to rat TRPV1 expressed in CHO cells |
Bioorg Med Chem Lett 15: 4143-50 (2005)
Article DOI: 10.1016/j.bmcl.2005.06.006
BindingDB Entry DOI: 10.7270/Q2JH3KQB |
More data for this
Ligand-Target Pair | |
Transient receptor potential cation channel subfamily V member 1
(Rattus norvegicus (rat)) | BDBM50169736
(2-(4-tert-Butyl-phenyl)-N-hydroxy-N-(4-methanesulf...)Show SMILES CC(C)(C)c1ccc(CC(=O)N(O)Cc2ccc(NS(C)(=O)=O)cc2)cc1 Show InChI InChI=1S/C20H26N2O4S/c1-20(2,3)17-9-5-15(6-10-17)13-19(23)22(24)14-16-7-11-18(12-8-16)21-27(4,25)26/h5-12,21,24H,13-14H2,1-4H3 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| 5.30E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Seoul National University
Curated by ChEMBL
| Assay Description
In vitro inhibition of [3H]-RTX binding to rat TRPV1 expressed in CHO cells |
Bioorg Med Chem Lett 15: 4143-50 (2005)
Article DOI: 10.1016/j.bmcl.2005.06.006
BindingDB Entry DOI: 10.7270/Q2JH3KQB |
More data for this
Ligand-Target Pair | |
Transient receptor potential cation channel subfamily V member 1
(Rattus norvegicus (rat)) | BDBM50169737
((4-Methanesulfonylamino-benzyl)-thiocarbamic acid ...)Show SMILES CC(C)(C)c1ccc(COC(=S)NCc2ccc(NS(C)(=O)=O)cc2)cc1 Show InChI InChI=1S/C20H26N2O3S2/c1-20(2,3)17-9-5-16(6-10-17)14-25-19(26)21-13-15-7-11-18(12-8-15)22-27(4,23)24/h5-12,22H,13-14H2,1-4H3,(H,21,26) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 6.25E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Seoul National University
Curated by ChEMBL
| Assay Description
Antagonist activity towards rat TRPV1 expressed in CHO cells |
Bioorg Med Chem Lett 15: 4143-50 (2005)
Article DOI: 10.1016/j.bmcl.2005.06.006
BindingDB Entry DOI: 10.7270/Q2JH3KQB |
More data for this
Ligand-Target Pair | |
Transient receptor potential cation channel subfamily V member 1
(Rattus norvegicus (rat)) | BDBM50169730
(CHEMBL362112 | N-{4-[(methylsulfonyl)amino]benzyl}...)Show SMILES CC(C)(C)c1ccc(NNC(=S)NCc2ccc(NS(C)(=O)=O)cc2)cc1 Show InChI InChI=1S/C19H26N4O2S2/c1-19(2,3)15-7-11-16(12-8-15)21-22-18(26)20-13-14-5-9-17(10-6-14)23-27(4,24)25/h5-12,21,23H,13H2,1-4H3,(H2,20,22,26) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 6.40E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Seoul National University
Curated by ChEMBL
| Assay Description
In vitro inhibition of [3H]-RTX binding to rat TRPV1 expressed in CHO cells |
Bioorg Med Chem Lett 15: 4143-50 (2005)
Article DOI: 10.1016/j.bmcl.2005.06.006
BindingDB Entry DOI: 10.7270/Q2JH3KQB |
More data for this
Ligand-Target Pair | |
Transient receptor potential cation channel subfamily V member 1
(Rattus norvegicus (rat)) | BDBM50169720
(CHEMBL361694 | N-(4-tert-Butyl-benzyl)-N-hydroxy-2...)Show SMILES CC(C)(C)c1ccc(CN(O)C(=O)Cc2ccc(NS(C)(=O)=O)cc2)cc1 Show InChI InChI=1S/C20H26N2O4S/c1-20(2,3)17-9-5-16(6-10-17)14-22(24)19(23)13-15-7-11-18(12-8-15)21-27(4,25)26/h5-12,21,24H,13-14H2,1-4H3 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| 6.40E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Seoul National University
Curated by ChEMBL
| Assay Description
In vitro inhibition of [3H]-RTX binding to rat TRPV1 expressed in CHO cells |
Bioorg Med Chem Lett 15: 4143-50 (2005)
Article DOI: 10.1016/j.bmcl.2005.06.006
BindingDB Entry DOI: 10.7270/Q2JH3KQB |
More data for this
Ligand-Target Pair | |
Transient receptor potential cation channel subfamily V member 1
(Rattus norvegicus (rat)) | BDBM50169720
(CHEMBL361694 | N-(4-tert-Butyl-benzyl)-N-hydroxy-2...)Show SMILES CC(C)(C)c1ccc(CN(O)C(=O)Cc2ccc(NS(C)(=O)=O)cc2)cc1 Show InChI InChI=1S/C20H26N2O4S/c1-20(2,3)17-9-5-16(6-10-17)14-22(24)19(23)13-15-7-11-18(12-8-15)21-27(4,25)26/h5-12,21,24H,13-14H2,1-4H3 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| 6.60E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Seoul National University
Curated by ChEMBL
| Assay Description
Antagonist activity towards rat TRPV1 expressed in CHO cells |
Bioorg Med Chem Lett 15: 4143-50 (2005)
Article DOI: 10.1016/j.bmcl.2005.06.006
BindingDB Entry DOI: 10.7270/Q2JH3KQB |
More data for this
Ligand-Target Pair | |
Transient receptor potential cation channel subfamily V member 1
(Rattus norvegicus (rat)) | BDBM50169725
(2-(4-tert-Butyl-phenyl)-N-(4-methanesulfonylamino-...)Show SMILES CC(C)(C)c1ccc(CC(=O)NCc2ccc(NS(C)(=O)=O)cc2)cc1 Show InChI InChI=1S/C20H26N2O3S/c1-20(2,3)17-9-5-15(6-10-17)13-19(23)21-14-16-7-11-18(12-8-16)22-26(4,24)25/h5-12,22H,13-14H2,1-4H3,(H,21,23) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 6.76E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Seoul National University
Curated by ChEMBL
| Assay Description
Antagonist activity towards rat TRPV1 expressed in CHO cells |
Bioorg Med Chem Lett 15: 4143-50 (2005)
Article DOI: 10.1016/j.bmcl.2005.06.006
BindingDB Entry DOI: 10.7270/Q2JH3KQB |
More data for this
Ligand-Target Pair | |
Transient receptor potential cation channel subfamily V member 1
(Rattus norvegicus (rat)) | BDBM50169729
(CHEMBL189569 | N-[3-(3,4-Dimethyl-phenyl)-propyl]-...)Show SMILES Cc1ccc(CCCNC(=O)Cc2ccc(NS(C)(=O)=O)cc2)cc1C Show InChI InChI=1S/C20H26N2O3S/c1-15-6-7-17(13-16(15)2)5-4-12-21-20(23)14-18-8-10-19(11-9-18)22-26(3,24)25/h6-11,13,22H,4-5,12,14H2,1-3H3,(H,21,23) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 7.18E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Seoul National University
Curated by ChEMBL
| Assay Description
In vitro inhibition of [3H]-RTX binding to rat TRPV1 expressed in CHO cells |
Bioorg Med Chem Lett 15: 4143-50 (2005)
Article DOI: 10.1016/j.bmcl.2005.06.006
BindingDB Entry DOI: 10.7270/Q2JH3KQB |
More data for this
Ligand-Target Pair | |
Transient receptor potential cation channel subfamily V member 1
(Rattus norvegicus (rat)) | BDBM50169718
((4-Methanesulfonylamino-3-methoxy-benzyl)-thiocarb...)Show SMILES COc1cc(CNC(=S)OCc2ccc(cc2)C(C)(C)C)ccc1NS(C)(=O)=O Show InChI InChI=1S/C21H28N2O4S2/c1-21(2,3)17-9-6-15(7-10-17)14-27-20(28)22-13-16-8-11-18(19(12-16)26-4)23-29(5,24)25/h6-12,23H,13-14H2,1-5H3,(H,22,28) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 8.40E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Seoul National University
Curated by ChEMBL
| Assay Description
Antagonist activity towards rat TRPV1 expressed in CHO cells |
Bioorg Med Chem Lett 15: 4143-50 (2005)
Article DOI: 10.1016/j.bmcl.2005.06.006
BindingDB Entry DOI: 10.7270/Q2JH3KQB |
More data for this
Ligand-Target Pair | |
Transient receptor potential cation channel subfamily V member 1
(Rattus norvegicus (rat)) | BDBM50169719
(CHEMBL186221 | N-(4-tert-butylbenzyl)-2-{4-[(methy...)Show SMILES CC(C)(C)c1ccc(CNC(=S)NNc2ccc(NS(C)(=O)=O)cc2)cc1 Show InChI InChI=1S/C19H26N4O2S2/c1-19(2,3)15-7-5-14(6-8-15)13-20-18(26)22-21-16-9-11-17(12-10-16)23-27(4,24)25/h5-12,21,23H,13H2,1-4H3,(H2,20,22,26) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 1.21E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Seoul National University
Curated by ChEMBL
| Assay Description
In vitro inhibition of [3H]-RTX binding to rat TRPV1 expressed in CHO cells |
Bioorg Med Chem Lett 15: 4143-50 (2005)
Article DOI: 10.1016/j.bmcl.2005.06.006
BindingDB Entry DOI: 10.7270/Q2JH3KQB |
More data for this
Ligand-Target Pair | |
Transient receptor potential cation channel subfamily V member 1
(Rattus norvegicus (rat)) | BDBM50169729
(CHEMBL189569 | N-[3-(3,4-Dimethyl-phenyl)-propyl]-...)Show SMILES Cc1ccc(CCCNC(=O)Cc2ccc(NS(C)(=O)=O)cc2)cc1C Show InChI InChI=1S/C20H26N2O3S/c1-15-6-7-17(13-16(15)2)5-4-12-21-20(23)14-18-8-10-19(11-9-18)22-26(3,24)25/h6-11,13,22H,4-5,12,14H2,1-3H3,(H,21,23) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 1.36E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Seoul National University
Curated by ChEMBL
| Assay Description
Antagonist activity towards rat TRPV1 expressed in CHO cells |
Bioorg Med Chem Lett 15: 4143-50 (2005)
Article DOI: 10.1016/j.bmcl.2005.06.006
BindingDB Entry DOI: 10.7270/Q2JH3KQB |
More data for this
Ligand-Target Pair | |
Transient receptor potential cation channel subfamily V member 1
(Rattus norvegicus (rat)) | BDBM50169739
(2-(4-Methanesulfonylamino-phenyl)-N-octadec-9-enyl...)Show SMILES CCCCCCCC\C=C/CCCCCCCCNC(=O)Cc1ccc(NS(C)(=O)=O)cc1 Show InChI InChI=1S/C27H46N2O3S/c1-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-18-23-28-27(30)24-25-19-21-26(22-20-25)29-33(2,31)32/h10-11,19-22,29H,3-9,12-18,23-24H2,1-2H3,(H,28,30)/b11-10- | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
| Article
PubMed
| >2.50E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Seoul National University
Curated by ChEMBL
| Assay Description
In vitro inhibition of [3H]-RTX binding to rat TRPV1 expressed in CHO cells |
Bioorg Med Chem Lett 15: 4143-50 (2005)
Article DOI: 10.1016/j.bmcl.2005.06.006
BindingDB Entry DOI: 10.7270/Q2JH3KQB |
More data for this
Ligand-Target Pair | |
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