Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
D(2) dopamine receptor (Rattus norvegicus (rat)) | BDBM50040079 (CHEMBL308524 | N-(1-Ethyl-pyrrolidin-2-ylmethyl)-2...) | PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | 0.0190 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Pennsylvania Curated by ChEMBL | Assay Description Inhibition constant against dopamine receptor D2 in rat | J Med Chem 36: 221-8 (1993) BindingDB Entry DOI: 10.7270/Q2TT4Q10 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
D(2) dopamine receptor (Rattus norvegicus (rat)) | BDBM50008785 (CHEMBL42953 | N-(1-Ethyl-pyrrolidin-2-ylmethyl)-5-...) | PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | 0.0200 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Pennsylvania Curated by ChEMBL | Assay Description Inhibition constant against dopamine receptor D2 in rat | J Med Chem 36: 221-8 (1993) BindingDB Entry DOI: 10.7270/Q2TT4Q10 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
D(2) dopamine receptor (Rattus norvegicus (rat)) | BDBM50008782 (CHEMBL44237 | EPIDEPRIDE | Epidepride;N-(1-Ethyl-p...) | PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | 0.0250 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Pennsylvania Curated by ChEMBL | Assay Description Inhibition constant against dopamine receptor D2 in rat | J Med Chem 36: 221-8 (1993) BindingDB Entry DOI: 10.7270/Q2TT4Q10 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
D(2) dopamine receptor (Rattus norvegicus (rat)) | BDBM50007518 ((S)-3-chloro-5-ethyl-N-((1-ethylpyrrolidin-2-yl)me...) | PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL MCE MMDB PC cid PC sid PDB UniChem Patents Similars | PubMed | 0.0900 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Pennsylvania Curated by ChEMBL | Assay Description Compound was evaluated for the inhibition constant against dopamine receptor D2 in rat | J Med Chem 36: 221-8 (1993) BindingDB Entry DOI: 10.7270/Q2TT4Q10 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
D(2) dopamine receptor (Rattus norvegicus (rat)) | BDBM50040077 (5-Iodo-2,3-dihydro-benzofuran-7-carboxylic acid [1...) | PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | 0.106 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Pennsylvania Curated by ChEMBL | Assay Description Inhibition constant against dopamine receptor D2 in rat | J Med Chem 36: 221-8 (1993) BindingDB Entry DOI: 10.7270/Q2TT4Q10 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
D(2) dopamine receptor (Rattus norvegicus (rat)) | BDBM50007521 (5-Bromo-N-[1-(4-fluoro-benzyl)-pyrrolidin-2-ylmeth...) | PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | 0.147 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Pennsylvania Curated by ChEMBL | Assay Description Inhibition constant against dopamine receptor D2 in rat | J Med Chem 36: 221-8 (1993) BindingDB Entry DOI: 10.7270/Q2TT4Q10 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
D(1A) dopamine receptor (RAT) | BDBM82247 (8-Chloro-3-methyl-5-phenyl-2,3,4,5-tetrahydro-1H-b...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL MCE PC cid PC sid UniChem Similars | PubMed | 0.390 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Pennsylvania Curated by ChEMBL | Assay Description In vitro binding affinity of the compound towards Dopamine receptor D1 by displacing [125I]-FISCH radioligand in rat striatal homogenate | J Med Chem 32: 1431-5 (1989) BindingDB Entry DOI: 10.7270/Q2KD1WWT | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
D(2) dopamine receptor (Rattus norvegicus (rat)) | BDBM50012961 ((-)-(S)-N-((1-ethylpyrrolidin-2-yl)methyl)-2-hydro...) | PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | 0.430 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Pennsylvania Curated by ChEMBL | Assay Description Inhibition constant against dopamine receptor D2 in rat | J Med Chem 36: 221-8 (1993) BindingDB Entry DOI: 10.7270/Q2TT4Q10 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
5-hydroxytryptamine receptor 1A (Rattus norvegicus (rat)) | BDBM82517 (2-{4-[4-(2-Methoxy-phenyl)-piperazin-1-yl]-butyl}-...) | PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL MCE PC cid PC sid UniChem Similars | PubMed | 0.600 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Pennsylvania Curated by ChEMBL | Assay Description In vitro binding affinity to 5-hydroxytryptamine 1A receptor using [125I](R)-(+)-trans-8-OH-PIPAT as radioligand in rat hippocampal homogenate | J Med Chem 37: 4572-5 (1995) BindingDB Entry DOI: 10.7270/Q24X58F6 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
D(3) dopamine receptor (Homo sapiens (Human)) | BDBM50038278 (6-[((E)-3-Iodo-allyl)-propyl-amino]-5,6,7,8-tetrah...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | 0.990 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Pennsylvania Curated by ChEMBL | Assay Description Tested for the inhibitory activity against Dopamine D3 receptor in infected Sf9 cells | J Med Chem 37: 4245-50 (1995) BindingDB Entry DOI: 10.7270/Q2S46R0H | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
D(2) dopamine receptor (Rattus norvegicus (rat)) | BDBM50005118 ((S)-3,5-Dichloro-N-(1-ethyl-pyrrolidin-2-ylmethyl)...) | PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars | PubMed | 1.10 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Pennsylvania Curated by ChEMBL | Assay Description Inhibition constant against dopamine receptor D2 in rat | J Med Chem 36: 221-8 (1993) BindingDB Entry DOI: 10.7270/Q2TT4Q10 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
5-hydroxytryptamine receptor 1A (Homo sapiens (Human)) | BDBM50020580 (1-[2-(3-Azido-phenyl)-ethyl]-4-(3-trifluoromethyl-...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | 1.5 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Pennsylvania Curated by ChEMBL | Assay Description Compound was tested in vitro for the inhibition of [3H]-DPAT (1 nM) binding to 5-HT1A receptor from bovine hippocampus | J Med Chem 32: 543-7 (1989) BindingDB Entry DOI: 10.7270/Q2H41QD3 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
D(2) dopamine receptor (Rattus norvegicus (rat)) | BDBM50040082 (CHEMBL307023 | N-(1-Ethyl-pyrrolidin-2-ylmethyl)-2...) | PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | 1.5 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Pennsylvania Curated by ChEMBL | Assay Description Inhibition constant against dopamine receptor D2 in rat | J Med Chem 36: 221-8 (1993) BindingDB Entry DOI: 10.7270/Q2TT4Q10 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sigma non-opioid intracellular receptor 1 (RAT) | BDBM50038281 (7-((E)-3-Iodo-allylamino)-5,6,7,8-tetrahydro-napht...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | 1.68 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Pennsylvania Curated by ChEMBL | Assay Description tested for the inhibitory activity against sigma receptor rat cerebellar | J Med Chem 37: 4245-50 (1995) BindingDB Entry DOI: 10.7270/Q2S46R0H | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
D(1A) dopamine receptor (RAT) | BDBM50016794 (8-Chloro-5-(4-iodo-phenyl)-3-methyl-2,3,4,5-tetrah...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | PubMed | 1.70 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Pennsylvania Curated by ChEMBL | Assay Description In vitro binding affinity of the compound towards Dopamine receptor D1 by displacing [125I]-FISCH radioligand in rat striatal homogenate | J Med Chem 32: 1431-5 (1989) BindingDB Entry DOI: 10.7270/Q2KD1WWT | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
D(3) dopamine receptor (Homo sapiens (Human)) | BDBM50038276 ((R,S) 7-[(3-Iodo-allyl)-propyl-amino]-5,6,7,8-tetr...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Similars | PubMed | 1.85 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Pennsylvania Curated by ChEMBL | Assay Description Tested for the inhibitory activity against Dopamine D3 receptor in infected Sf9 cells | J Med Chem 37: 4245-50 (1995) BindingDB Entry DOI: 10.7270/Q2S46R0H | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
5-hydroxytryptamine receptor 1A (Rattus norvegicus (rat)) | BDBM50035512 (CHEMBL140697 | N-{2-[4-(2-Methoxy-phenyl)-piperazi...) | PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | 2.20 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Pennsylvania Curated by ChEMBL | Assay Description In vitro binding affinity to 5-hydroxytryptamine 1A receptor in rat hippocampal homogenate by [125I](R)-(+)-trans-8-OH-PIPAT displacement. | J Med Chem 37: 4572-5 (1995) BindingDB Entry DOI: 10.7270/Q24X58F6 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
D(3) dopamine receptor (Homo sapiens (Human)) | BDBM50038280 (6-[((E)-3-Iodo-allyl)-propyl-amino]-5,6,7,8-tetrah...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | 2.20 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Pennsylvania Curated by ChEMBL | Assay Description Tested for the inhibitory activity against Dopamine D3 receptor in infected Sf9 cells | J Med Chem 37: 4245-50 (1995) BindingDB Entry DOI: 10.7270/Q2S46R0H | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
5-hydroxytryptamine receptor 1A (Homo sapiens (Human)) | BDBM50020580 (1-[2-(3-Azido-phenyl)-ethyl]-4-(3-trifluoromethyl-...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | 2.5 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Pennsylvania Curated by ChEMBL | Assay Description Compound was tested in vitro for the inhibition of [3H]-5-HT (2 nM) binding to 5-hydroxytryptamine 1A receptor from bovine hippocampus | J Med Chem 32: 543-7 (1989) BindingDB Entry DOI: 10.7270/Q2H41QD3 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
5-hydroxytryptamine receptor 1A (Rattus norvegicus (rat)) | BDBM50035515 (CHEMBL410521 | N-{2-[4-(2-Methoxy-phenyl)-piperazi...) | PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | PubMed | 2.5 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Pennsylvania Curated by ChEMBL | Assay Description In vitro binding affinity to 5-hydroxytryptamine 1A receptor in rat hippocampal homogenate by [125I](R)-(+)-trans-8-OH-PIPAT displacement. | J Med Chem 37: 4572-5 (1995) BindingDB Entry DOI: 10.7270/Q24X58F6 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
5-hydroxytryptamine receptor 1A (Rattus norvegicus (rat)) | BDBM50035508 (4-Iodo-N-{2-[4-(2-methoxy-phenyl)-piperazin-1-yl]-...) | PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL MCE PC cid PC sid UniChem Similars | PubMed | 2.60 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Pennsylvania Curated by ChEMBL | Assay Description In vitro binding affinity to 5-hydroxytryptamine 1A receptor in rat hippocampal homogenate by [125I](R)-(+)-trans-8-OH-PIPAT displacement. | J Med Chem 37: 4572-5 (1995) BindingDB Entry DOI: 10.7270/Q24X58F6 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
5-hydroxytryptamine receptor 1A (Homo sapiens (Human)) | BDBM10755 (14C-5-hydroxy tryptamine creatinine disulfate | 2-...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase CHEMBL MCE KEGG PC cid PC sid PDB UniChem Similars | PDB PubMed | 2.80 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Pennsylvania Curated by ChEMBL | Assay Description Compound was tested in vitro for the inhibition of [3H]-5-HT (2 nM) binding to 5-hydroxytryptamine 1A receptor from bovine hippocampus | J Med Chem 32: 543-7 (1989) BindingDB Entry DOI: 10.7270/Q2H41QD3 | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (crystal) | ||||||||||||
D(3) dopamine receptor (Homo sapiens (Human)) | BDBM50020222 ((+/-)-7-(dipropylamino)-5,6,7,8-tetrahydronaphthal...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Patents Similars | PubMed | 2.90 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Pennsylvania Curated by ChEMBL | Assay Description Tested for the inhibitory activity against Dopamine D3 receptor in infected Sf9 cells | J Med Chem 37: 4245-50 (1995) BindingDB Entry DOI: 10.7270/Q2S46R0H | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
5-hydroxytryptamine receptor 1A (Homo sapiens (Human)) | BDBM10755 (14C-5-hydroxy tryptamine creatinine disulfate | 2-...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase CHEMBL MCE KEGG PC cid PC sid PDB UniChem Similars | PDB PubMed | 3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Pennsylvania Curated by ChEMBL | Assay Description Compound was tested in vitro for the inhibition of [3H]-DPAT (1 nM) binding to 5-hydroxytryptamine 1A receptor from bovine hippocampus | J Med Chem 32: 543-7 (1989) BindingDB Entry DOI: 10.7270/Q2H41QD3 | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (crystal) | ||||||||||||
D(2) dopamine receptor (Rattus norvegicus (rat)) | BDBM50012967 (CHEMBL49897 | N-(1-Ethyl-pyrrolidin-2-ylmethyl)-5-...) | PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | 3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Pennsylvania Curated by ChEMBL | Assay Description Inhibition constant against dopamine receptor D2 in rat | J Med Chem 36: 221-8 (1993) BindingDB Entry DOI: 10.7270/Q2TT4Q10 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
5-hydroxytryptamine receptor 1A (Rattus norvegicus (rat)) | BDBM50035513 (4-Fluoro-N-{2-[4-(2-methoxy-phenyl)-piperazin-1-yl...) | PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Patents Similars | PubMed | 3.20 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Pennsylvania Curated by ChEMBL | Assay Description In vitro binding affinity to 5-hydroxytryptamine 1A receptor in rat hippocampal homogenate by [125I](R)-(+)-trans-8-OH-PIPAT displacement. | J Med Chem 37: 4572-5 (1995) BindingDB Entry DOI: 10.7270/Q24X58F6 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sigma non-opioid intracellular receptor 1 (RAT) | BDBM50038276 ((R,S) 7-[(3-Iodo-allyl)-propyl-amino]-5,6,7,8-tetr...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Similars | PubMed | 3.20 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Pennsylvania Curated by ChEMBL | Assay Description Tested for the inhibitory activity against sigma receptor rat cerebellar | J Med Chem 37: 4245-50 (1995) BindingDB Entry DOI: 10.7270/Q2S46R0H | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
5-hydroxytryptamine receptor 1A (Rattus norvegicus (rat)) | BDBM50035510 (4-Chloromethyl-N-{2-[4-(2-methoxy-phenyl)-piperazi...) | PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | 3.5 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Pennsylvania Curated by ChEMBL | Assay Description In vitro binding affinity to 5-hydroxytryptamine 1A receptor in rat hippocampal homogenate by [125I](R)-(+)-trans-8-OH-PIPAT displacement. | J Med Chem 37: 4572-5 (1995) BindingDB Entry DOI: 10.7270/Q24X58F6 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
D(2) dopamine receptor (Homo sapiens (Human)) | BDBM50038278 (6-[((E)-3-Iodo-allyl)-propyl-amino]-5,6,7,8-tetrah...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | 3.60 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Pennsylvania Curated by ChEMBL | Assay Description Tested for the inhibitory activity against D2H (high-affinity states) receptor in infected HEK 293 cells. | J Med Chem 37: 4245-50 (1995) BindingDB Entry DOI: 10.7270/Q2S46R0H | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
5-hydroxytryptamine receptor 1A (Homo sapiens (Human)) | BDBM50020579 (3-{2-[4-(3-Trifluoromethyl-phenyl)-piperazin-1-yl]...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | PubMed | 4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Pennsylvania Curated by ChEMBL | Assay Description Compound was tested in vitro for the inhibition of [3H]-5-HT (2 nM) binding to 5-HT1A receptor from bovine hippocampus | J Med Chem 32: 543-7 (1989) BindingDB Entry DOI: 10.7270/Q2H41QD3 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
5-hydroxytryptamine receptor 1A (Homo sapiens (Human)) | BDBM50020579 (3-{2-[4-(3-Trifluoromethyl-phenyl)-piperazin-1-yl]...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | PubMed | 5 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Pennsylvania Curated by ChEMBL | Assay Description Compound was tested in vitro for the inhibition of [3H]-DPAT (1 nM) binding to 5-HT1A receptor from bovine hippocampus | J Med Chem 32: 543-7 (1989) BindingDB Entry DOI: 10.7270/Q2H41QD3 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
5-hydroxytryptamine receptor 1A (Rattus norvegicus (rat)) | BDBM50038276 ((R,S) 7-[(3-Iodo-allyl)-propyl-amino]-5,6,7,8-tetr...) | PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Similars | PubMed | 5.10 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Pennsylvania Curated by ChEMBL | Assay Description Tested for the inhibitory activity against 5-hydroxytryptamine 1A receptor in rat hippocampal | J Med Chem 37: 4245-50 (1995) BindingDB Entry DOI: 10.7270/Q2S46R0H | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
D(2) dopamine receptor (Homo sapiens (Human)) | BDBM50038276 ((R,S) 7-[(3-Iodo-allyl)-propyl-amino]-5,6,7,8-tetr...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Similars | PubMed | 6.60 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Pennsylvania Curated by ChEMBL | Assay Description Tested for the inhibitory activity against D2H (high-affinity states) receptor in infected HEK 293 cells. | J Med Chem 37: 4245-50 (1995) BindingDB Entry DOI: 10.7270/Q2S46R0H | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
D(3) dopamine receptor (Homo sapiens (Human)) | BDBM50038279 (3-[((E)-3-Iodo-allyl)-propyl-amino]-chroman-8-ol |...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | 6.69 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Pennsylvania Curated by ChEMBL | Assay Description Tested for the inhibitory activity against Dopamine D3 receptor in infected Sf9 cells | J Med Chem 37: 4245-50 (1995) BindingDB Entry DOI: 10.7270/Q2S46R0H | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sodium-dependent serotonin transporter (Rattus norvegicus (rat)) | BDBM50055824 (2-{[(2R,3S)-3-(4-Chloro-phenyl)-8-methyl-8-aza-bic...) | PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem | Article PubMed | 7 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Pennsylvania Curated by ChEMBL | Assay Description In vitro binding affinity to Dopamine transporter in rat striatal homogenates using [125I]-IPT20 as the ligand | J Med Chem 40: 9-17 (1997) Article DOI: 10.1021/jm960532j BindingDB Entry DOI: 10.7270/Q2WM1CHJ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
5-hydroxytryptamine receptor 1A (Rattus norvegicus (rat)) | BDBM50035518 (4-Ethyl-N-{2-[4-(2-methoxy-phenyl)-piperazin-1-yl]...) | PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | 9.30 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Pennsylvania Curated by ChEMBL | Assay Description In vitro binding affinity to 5-hydroxytryptamine 1A receptor in rat hippocampal homogenate by [125I](R)-(+)-trans-8-OH-PIPAT displacement. | J Med Chem 37: 4572-5 (1995) BindingDB Entry DOI: 10.7270/Q24X58F6 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
D(2) dopamine receptor (Homo sapiens (Human)) | BDBM50038280 (6-[((E)-3-Iodo-allyl)-propyl-amino]-5,6,7,8-tetrah...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | 9.70 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Pennsylvania Curated by ChEMBL | Assay Description Tested for the inhibitory activity against D2H (high-affinity states) receptor in infected HEK 293 cells. | J Med Chem 37: 4245-50 (1995) BindingDB Entry DOI: 10.7270/Q2S46R0H | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
5-hydroxytryptamine receptor 1A (Rattus norvegicus (rat)) | BDBM50035525 (4-Amino-N-{2-[4-(2-methoxy-phenyl)-piperazin-1-yl]...) | PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | 10 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Pennsylvania Curated by ChEMBL | Assay Description In vitro binding affinity to 5-hydroxytryptamine 1A receptor in rat hippocampal homogenate by [125I](R)-(+)-trans-8-OH-PIPAT displacement. | J Med Chem 37: 4572-5 (1995) BindingDB Entry DOI: 10.7270/Q24X58F6 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
5-hydroxytryptamine receptor 1A (Rattus norvegicus (rat)) | BDBM50035514 (CHEMBL142082 | N-{2-[4-(2-Methoxy-phenyl)-piperazi...) | PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | 10 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Pennsylvania Curated by ChEMBL | Assay Description In vitro binding affinity to 5-hydroxytryptamine 1A receptor in rat hippocampal homogenate by [125I](R)-(+)-trans-8-OH-PIPAT displacement. | J Med Chem 37: 4572-5 (1995) BindingDB Entry DOI: 10.7270/Q24X58F6 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
D(2) dopamine receptor (Homo sapiens (Human)) | BDBM50038279 (3-[((E)-3-Iodo-allyl)-propyl-amino]-chroman-8-ol |...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | 11 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Pennsylvania Curated by ChEMBL | Assay Description Tested for the inhibitory activity against D2H (high-affinity states) receptor in infected HEK 293 cells. | J Med Chem 37: 4245-50 (1995) BindingDB Entry DOI: 10.7270/Q2S46R0H | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
5-hydroxytryptamine receptor 1A (Rattus norvegicus (rat)) | BDBM50035524 (4-Butyl-N-{2-[4-(2-methoxy-phenyl)-piperazin-1-yl]...) | PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | 13 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Pennsylvania Curated by ChEMBL | Assay Description In vitro binding affinity to 5-hydroxytryptamine 1A receptor in rat hippocampal homogenate by [125I](R)-(+)-trans-8-OH-PIPAT displacement. | J Med Chem 37: 4572-5 (1995) BindingDB Entry DOI: 10.7270/Q24X58F6 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
D(1A) dopamine receptor (RAT) | BDBM50016793 (8-Iodo-3-methyl-5-phenyl-2,3,4,5-tetrahydro-1H-ben...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem | PubMed | 13 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Pennsylvania Curated by ChEMBL | Assay Description In vitro binding affinity of the compound towards Dopamine receptor D1 by displacing [125I]-FISCH radioligand in rat striatal homogenate | J Med Chem 32: 1431-5 (1989) BindingDB Entry DOI: 10.7270/Q2KD1WWT | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
D(2) dopamine receptor (Rattus norvegicus (rat)) | BDBM50040078 (CHEMBL305844 | N-(1-Ethyl-pyrrolidin-2-ylmethyl)-2...) | PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | 13 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Pennsylvania Curated by ChEMBL | Assay Description Inhibition constant against dopamine receptor D2 in rat | J Med Chem 36: 221-8 (1993) BindingDB Entry DOI: 10.7270/Q2TT4Q10 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sodium-dependent serotonin transporter (Rattus norvegicus (rat)) | BDBM50055825 (CHEMBL295441 | Rhenium Compound) | PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC sid UniChem Similars | Article PubMed | 14 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Pennsylvania Curated by ChEMBL | Assay Description In vitro binding affinity of the compound towards dopamine transporter using [125I]-IPT20 as radioligand in rat striatal homogenates | J Med Chem 40: 9-17 (1997) Article DOI: 10.1021/jm960532j BindingDB Entry DOI: 10.7270/Q2WM1CHJ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
5-hydroxytryptamine receptor 1A (Rattus norvegicus (rat)) | BDBM50035511 (CHEMBL139869 | N-{2-[4-(2-Methoxy-phenyl)-piperazi...) | PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | 16 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Pennsylvania Curated by ChEMBL | Assay Description In vitro binding affinity to 5-hydroxytryptamine 1A receptor in rat hippocampal homogenate by [125I](R)-(+)-trans-8-OH-PIPAT displacement. | J Med Chem 37: 4572-5 (1995) BindingDB Entry DOI: 10.7270/Q24X58F6 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
5-hydroxytryptamine receptor 1A (Homo sapiens (Human)) | BDBM50020578 (1-[2-(4-Azido-3-iodo-phenyl)-ethyl]-4-(3-trifluoro...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | 18 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Pennsylvania Curated by ChEMBL | Assay Description Compound was tested in vitro for the inhibition of [3H]-5-HT (2 nM) binding to 5-HT1A receptor from bovine hippocampus | J Med Chem 32: 543-7 (1989) BindingDB Entry DOI: 10.7270/Q2H41QD3 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
5-hydroxytryptamine receptor 1A (Rattus norvegicus (rat)) | BDBM50035516 (4-Amino-3-iodo-N-{2-[4-(2-methoxy-phenyl)-piperazi...) | PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | 18 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Pennsylvania Curated by ChEMBL | Assay Description In vitro binding affinity to 5-hydroxytryptamine 1A receptor in rat hippocampal homogenate by [125I](R)-(+)-trans-8-OH-PIPAT displacement. | J Med Chem 37: 4572-5 (1995) BindingDB Entry DOI: 10.7270/Q24X58F6 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
5-hydroxytryptamine receptor 1A (Homo sapiens (Human)) | BDBM50020581 (2-Iodo-4-{2-[4-(3-trifluoromethyl-phenyl)-piperazi...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | 19 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Pennsylvania Curated by ChEMBL | Assay Description Compound was tested in vitro for the inhibition of [3H]-5-HT (2 nM) binding to 5-hydroxytryptamine 1A receptor from bovine hippocampus | J Med Chem 32: 543-7 (1989) BindingDB Entry DOI: 10.7270/Q2H41QD3 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
5-hydroxytryptamine receptor 1A (Homo sapiens (Human)) | BDBM50020581 (2-Iodo-4-{2-[4-(3-trifluoromethyl-phenyl)-piperazi...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | 20 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Pennsylvania Curated by ChEMBL | Assay Description Compound was tested in vitro for the inhibition of [3H]-5-HT (2 nM) binding to 5-HT1A receptor from bovine hippocampus | J Med Chem 32: 543-7 (1989) BindingDB Entry DOI: 10.7270/Q2H41QD3 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
5-hydroxytryptamine receptor 1A (Homo sapiens (Human)) | BDBM50020578 (1-[2-(4-Azido-3-iodo-phenyl)-ethyl]-4-(3-trifluoro...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | 20 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Pennsylvania Curated by ChEMBL | Assay Description Compound was tested in vitro for the inhibition of [3H]-5-HT (2 nM) binding to 5-HT1A receptor from bovine hippocampus | J Med Chem 32: 543-7 (1989) BindingDB Entry DOI: 10.7270/Q2H41QD3 | |||||||||||
More data for this Ligand-Target Pair |
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