Compile Data Set for Download or QSAR

Found 224 hits with Last Name = 'cohen' and Initial = 'jd'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Estrogen receptor (Homo sapiens (Human))	BDBM443430 (US10654866, Example 1B | US11117902, Example 1A | ...) Show SMILES Oc1ccc2c3[C@@H](Oc4cc(ccc4-c3cnc2c1)C(F)(F)F)c1ccc(OCCN2CC(CF)C2)cc1 |r| Show InChI InChI=1S/C29H24F4N2O3/c30-13-17-15-35(16-17)9-10-37-21-5-1-18(2-6-21)28-27-23-8-4-20(36)12-25(23)34-14-24(27)22-7-3-19(29(31,32)33)11-26(22)38-28/h1-8,11-12,14,17,28,36H,9-10,13,15-16H2/t28-/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem		0.310	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details BindingDB Entry DOI: 10.7270/Q2JM2FKJ
					More data for this Ligand-Target Pair
Estrogen receptor (Homo sapiens (Human))	BDBM443430 (US10654866, Example 1B | US11117902, Example 1A | ...) Show SMILES Oc1ccc2c3[C@@H](Oc4cc(ccc4-c3cnc2c1)C(F)(F)F)c1ccc(OCCN2CC(CF)C2)cc1 |r| Show InChI InChI=1S/C29H24F4N2O3/c30-13-17-15-35(16-17)9-10-37-21-5-1-18(2-6-21)28-27-23-8-4-20(36)12-25(23)34-14-24(27)22-7-3-19(29(31,32)33)11-26(22)38-28/h1-8,11-12,14,17,28,36H,9-10,13,15-16H2/t28-/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem	US Patent	0.310	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Eli Lilly and Company US Patent					Assay Description Run the competition binding assay in a buffer containing 50 mM HEPES, pH 7.5, 1.5 mM EDTA, 150 mM NaCl, 10% glycerol, 1 mg/mL ovalbumin, and 5 mM DTT...				US Patent US10654866 (2020) BindingDB Entry DOI: 10.7270/Q2D50R05
					More data for this Ligand-Target Pair
Estrogen receptor (Homo sapiens (Human))	BDBM443429 (US10654866, Example 1A | US11117902, Example 1B | ...) Show SMILES Oc1ccc2c3[C@H](Oc4cc(ccc4-c3cnc2c1)C(F)(F)F)c1ccc(OCCN2CC(CF)C2)cc1 |r| Show InChI InChI=1S/C29H24F4N2O3/c30-13-17-15-35(16-17)9-10-37-21-5-1-18(2-6-21)28-27-23-8-4-20(36)12-25(23)34-14-24(27)22-7-3-19(29(31,32)33)11-26(22)38-28/h1-8,11-12,14,17,28,36H,9-10,13,15-16H2/t28-/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem	US Patent	0.310	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The purpose of the following ER competition binding assays is to determine the affinity of a test compound against ERα (wild type), ERα (Y5...				Citation and Details BindingDB Entry DOI: 10.7270/Q22B926M
					More data for this Ligand-Target Pair
Estrogen receptor (Homo sapiens (Human))	BDBM443444 (US10654866, Example 4B | US11117902, Example 4A | ...) Show SMILES Oc1ccc2c3[C@@H](Oc4c(Cl)cccc4-c3cnc2c1)c1ccc(OCCN2CC(CF)C2)cc1 |r| Show InChI InChI=1S/C28H24ClFN2O3/c29-24-3-1-2-21-23-14-31-25-12-19(33)6-9-22(25)26(23)27(35-28(21)24)18-4-7-20(8-5-18)34-11-10-32-15-17(13-30)16-32/h1-9,12,14,17,27,33H,10-11,13,15-16H2/t27-/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem		0.340	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details BindingDB Entry DOI: 10.7270/Q2JM2FKJ
					More data for this Ligand-Target Pair
Estrogen receptor (Homo sapiens (Human))	BDBM443437 (US10654866, Example 4A | US11117902, Example 4B | ...) Show SMILES Oc1ccc2c3[C@H](Oc4c(Cl)cccc4-c3cnc2c1)c1ccc(OCCN2CC(CF)C2)cc1 |r| Show InChI InChI=1S/C28H24ClFN2O3/c29-24-3-1-2-21-23-14-31-25-12-19(33)6-9-22(25)26(23)27(35-28(21)24)18-4-7-20(8-5-18)34-11-10-32-15-17(13-30)16-32/h1-9,12,14,17,27,33H,10-11,13,15-16H2/t27-/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	0.340	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The purpose of the following ER competition binding assays is to determine the affinity of a test compound against ERα (wild type), ERα (Y5...				Citation and Details BindingDB Entry DOI: 10.7270/Q22B926M
					More data for this Ligand-Target Pair
Estrogen receptor (Homo sapiens (Human))	BDBM443444 (US10654866, Example 4B | US11117902, Example 4A | ...) Show SMILES Oc1ccc2c3[C@@H](Oc4c(Cl)cccc4-c3cnc2c1)c1ccc(OCCN2CC(CF)C2)cc1 |r| Show InChI InChI=1S/C28H24ClFN2O3/c29-24-3-1-2-21-23-14-31-25-12-19(33)6-9-22(25)26(23)27(35-28(21)24)18-4-7-20(8-5-18)34-11-10-32-15-17(13-30)16-32/h1-9,12,14,17,27,33H,10-11,13,15-16H2/t27-/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	0.340	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Eli Lilly and Company US Patent					Assay Description Run the competition binding assay in a buffer containing 50 mM HEPES, pH 7.5, 1.5 mM EDTA, 150 mM NaCl, 10% glycerol, 1 mg/mL ovalbumin, and 5 mM DTT...				US Patent US10654866 (2020) BindingDB Entry DOI: 10.7270/Q2D50R05
					More data for this Ligand-Target Pair
Estrogen receptor (Homo sapiens (Human))	BDBM518821 (US11117902, Example 3B | US11634426, Example 3A) Show SMILES Oc1ccc2c3[C@H](Oc4cc(Cl)ccc4-c3cnc2c1)c1ccc(OCCN2CC(CF)C2)cc1 |r| Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	0.590	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The purpose of the following ER competition binding assays is to determine the affinity of a test compound against ERα (wild type), ERα (Y5...				Citation and Details BindingDB Entry DOI: 10.7270/Q22B926M
					More data for this Ligand-Target Pair
Estrogen receptor (Homo sapiens (Human))	BDBM443449 (US10654866, Example 3B | US11117902, Example 3A | ...) Show SMILES Oc1ccc2c3[C@@H](Oc4cc(Cl)ccc4-c3cnc2c1)c1ccc(OCCN2CC(CF)C2)cc1 |r| Show InChI InChI=1S/C28H24ClFN2O3/c29-19-3-7-22-24-14-31-25-12-20(33)4-8-23(25)27(24)28(35-26(22)11-19)18-1-5-21(6-2-18)34-10-9-32-15-17(13-30)16-32/h1-8,11-12,14,17,28,33H,9-10,13,15-16H2/t28-/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem		0.590	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details BindingDB Entry DOI: 10.7270/Q2JM2FKJ
					More data for this Ligand-Target Pair
Estrogen receptor (Homo sapiens (Human))	BDBM443449 (US10654866, Example 3B | US11117902, Example 3A | ...) Show SMILES Oc1ccc2c3[C@@H](Oc4cc(Cl)ccc4-c3cnc2c1)c1ccc(OCCN2CC(CF)C2)cc1 |r| Show InChI InChI=1S/C28H24ClFN2O3/c29-19-3-7-22-24-14-31-25-12-20(33)4-8-23(25)27(24)28(35-26(22)11-19)18-1-5-21(6-2-18)34-10-9-32-15-17(13-30)16-32/h1-8,11-12,14,17,28,33H,9-10,13,15-16H2/t28-/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	0.590	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Eli Lilly and Company US Patent					Assay Description Run the competition binding assay in a buffer containing 50 mM HEPES, pH 7.5, 1.5 mM EDTA, 150 mM NaCl, 10% glycerol, 1 mg/mL ovalbumin, and 5 mM DTT...				US Patent US10654866 (2020) BindingDB Entry DOI: 10.7270/Q2D50R05
					More data for this Ligand-Target Pair
Estrogen receptor (Homo sapiens (Human))	BDBM443450 (US10654866, Example 4 | US11117902, Example 4 | US...) Show SMILES Oc1ccc2c3C(Oc4c(Cl)cccc4-c3cnc2c1)c1ccc(OCCN2CC(CF)C2)cc1 Show InChI InChI=1S/C28H24ClFN2O3/c29-24-3-1-2-21-23-14-31-25-12-19(33)6-9-22(25)26(23)27(35-28(21)24)18-4-7-20(8-5-18)34-11-10-32-15-17(13-30)16-32/h1-9,12,14,17,27,33H,10-11,13,15-16H2	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	0.640	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Eli Lilly and Company US Patent					Assay Description Run the competition binding assay in a buffer containing 50 mM HEPES, pH 7.5, 1.5 mM EDTA, 150 mM NaCl, 10% glycerol, 1 mg/mL ovalbumin, and 5 mM DTT...				US Patent US10654866 (2020) BindingDB Entry DOI: 10.7270/Q2D50R05
					More data for this Ligand-Target Pair
Estrogen receptor (Homo sapiens (Human))	BDBM443450 (US10654866, Example 4 | US11117902, Example 4 | US...) Show SMILES Oc1ccc2c3C(Oc4c(Cl)cccc4-c3cnc2c1)c1ccc(OCCN2CC(CF)C2)cc1 Show InChI InChI=1S/C28H24ClFN2O3/c29-24-3-1-2-21-23-14-31-25-12-19(33)6-9-22(25)26(23)27(35-28(21)24)18-4-7-20(8-5-18)34-11-10-32-15-17(13-30)16-32/h1-9,12,14,17,27,33H,10-11,13,15-16H2	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	0.640	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The purpose of the following ER competition binding assays is to determine the affinity of a test compound against ERα (wild type), ERα (Y5...				Citation and Details BindingDB Entry DOI: 10.7270/Q22B926M
					More data for this Ligand-Target Pair
Estrogen receptor (Homo sapiens (Human))	BDBM443450 (US10654866, Example 4 | US11117902, Example 4 | US...) Show SMILES Oc1ccc2c3C(Oc4c(Cl)cccc4-c3cnc2c1)c1ccc(OCCN2CC(CF)C2)cc1 Show InChI InChI=1S/C28H24ClFN2O3/c29-24-3-1-2-21-23-14-31-25-12-19(33)6-9-22(25)26(23)27(35-28(21)24)18-4-7-20(8-5-18)34-11-10-32-15-17(13-30)16-32/h1-9,12,14,17,27,33H,10-11,13,15-16H2	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem		0.640	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details BindingDB Entry DOI: 10.7270/Q2JM2FKJ
					More data for this Ligand-Target Pair
Estrogen receptor (Homo sapiens (Human))	BDBM443434 (US10654866, Example 2B | US11117902, Example 2A | ...) Show SMILES Oc1ccc2c3[C@@H](Oc4c(cccc4C(F)(F)F)-c3cnc2c1)c1ccc(OCCN2CC(CF)C2)cc1 |r| Show InChI InChI=1S/C29H24F4N2O3/c30-13-17-15-35(16-17)10-11-37-20-7-4-18(5-8-20)27-26-22-9-6-19(36)12-25(22)34-14-23(26)21-2-1-3-24(28(21)38-27)29(31,32)33/h1-9,12,14,17,27,36H,10-11,13,15-16H2/t27-/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	0.650	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The purpose of the following ER competition binding assays is to determine the affinity of a test compound against ERα (wild type), ERα (Y5...				Citation and Details BindingDB Entry DOI: 10.7270/Q22B926M
					More data for this Ligand-Target Pair
Estrogen receptor (Homo sapiens (Human))	BDBM443433 (US10654866, Example 2A | US11117902, Example 2B | ...) Show SMILES Oc1ccc2c3[C@H](Oc4c(cccc4C(F)(F)F)-c3cnc2c1)c1ccc(OCCN2CC(CF)C2)cc1 |r| Show InChI InChI=1S/C29H24F4N2O3/c30-13-17-15-35(16-17)10-11-37-20-7-4-18(5-8-20)27-26-22-9-6-19(36)12-25(22)34-14-23(26)21-2-1-3-24(28(21)38-27)29(31,32)33/h1-9,12,14,17,27,36H,10-11,13,15-16H2/t27-/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	0.650	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Eli Lilly and Company US Patent					Assay Description Run the competition binding assay in a buffer containing 50 mM HEPES, pH 7.5, 1.5 mM EDTA, 150 mM NaCl, 10% glycerol, 1 mg/mL ovalbumin, and 5 mM DTT...				US Patent US10654866 (2020) BindingDB Entry DOI: 10.7270/Q2D50R05
					More data for this Ligand-Target Pair
Estrogen receptor (Homo sapiens (Human))	BDBM443433 (US10654866, Example 2A | US11117902, Example 2B | ...) Show SMILES Oc1ccc2c3[C@H](Oc4c(cccc4C(F)(F)F)-c3cnc2c1)c1ccc(OCCN2CC(CF)C2)cc1 |r| Show InChI InChI=1S/C29H24F4N2O3/c30-13-17-15-35(16-17)10-11-37-20-7-4-18(5-8-20)27-26-22-9-6-19(36)12-25(22)34-14-23(26)21-2-1-3-24(28(21)38-27)29(31,32)33/h1-9,12,14,17,27,36H,10-11,13,15-16H2/t27-/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem		0.650	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details BindingDB Entry DOI: 10.7270/Q2JM2FKJ
					More data for this Ligand-Target Pair
Estrogen receptor (Homo sapiens (Human))	BDBM443428 (Racemic 5-(4-{2-[3-(Fluoromethyl)azetidin-1-yl]eth...) Show SMILES Oc1ccc2c3C(Oc4cc(ccc4-c3cnc2c1)C(F)(F)F)c1ccc(OCCN2CC(CF)C2)cc1 Show InChI InChI=1S/C29H24F4N2O3/c30-13-17-15-35(16-17)9-10-37-21-5-1-18(2-6-21)28-27-23-8-4-20(36)12-25(23)34-14-24(27)22-7-3-19(29(31,32)33)11-26(22)38-28/h1-8,11-12,14,17,28,36H,9-10,13,15-16H2	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	0.870	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Eli Lilly and Company US Patent					Assay Description Run the competition binding assay in a buffer containing 50 mM HEPES, pH 7.5, 1.5 mM EDTA, 150 mM NaCl, 10% glycerol, 1 mg/mL ovalbumin, and 5 mM DTT...				US Patent US10654866 (2020) BindingDB Entry DOI: 10.7270/Q2D50R05
					More data for this Ligand-Target Pair
Estrogen receptor (Homo sapiens (Human))	BDBM443428 (Racemic 5-(4-{2-[3-(Fluoromethyl)azetidin-1-yl]eth...) Show SMILES Oc1ccc2c3C(Oc4cc(ccc4-c3cnc2c1)C(F)(F)F)c1ccc(OCCN2CC(CF)C2)cc1 Show InChI InChI=1S/C29H24F4N2O3/c30-13-17-15-35(16-17)9-10-37-21-5-1-18(2-6-21)28-27-23-8-4-20(36)12-25(23)34-14-24(27)22-7-3-19(29(31,32)33)11-26(22)38-28/h1-8,11-12,14,17,28,36H,9-10,13,15-16H2	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem		0.870	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details BindingDB Entry DOI: 10.7270/Q2JM2FKJ
					More data for this Ligand-Target Pair
Estrogen receptor (Homo sapiens (Human))	BDBM443428 (Racemic 5-(4-{2-[3-(Fluoromethyl)azetidin-1-yl]eth...) Show SMILES Oc1ccc2c3C(Oc4cc(ccc4-c3cnc2c1)C(F)(F)F)c1ccc(OCCN2CC(CF)C2)cc1 Show InChI InChI=1S/C29H24F4N2O3/c30-13-17-15-35(16-17)9-10-37-21-5-1-18(2-6-21)28-27-23-8-4-20(36)12-25(23)34-14-24(27)22-7-3-19(29(31,32)33)11-26(22)38-28/h1-8,11-12,14,17,28,36H,9-10,13,15-16H2	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	0.870	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The purpose of the following ER competition binding assays is to determine the affinity of a test compound against ERα (wild type), ERα (Y5...				Citation and Details BindingDB Entry DOI: 10.7270/Q22B926M
					More data for this Ligand-Target Pair
Estrogen receptor (Homo sapiens (Human))	BDBM443442 (US10654866, Example 8A | US11117902, Example 8A | ...) Show SMILES Cc1cccc-2c1O[C@@H](c1ccc(OCCN3CC(CF)C3)cc1)c1c-2cnc2cc(O)ccc12 |r| Show InChI InChI=1S/C29H27FN2O3/c1-18-3-2-4-23-25-15-31-26-13-21(33)7-10-24(26)27(25)29(35-28(18)23)20-5-8-22(9-6-20)34-12-11-32-16-19(14-30)17-32/h2-10,13,15,19,29,33H,11-12,14,16-17H2,1H3/t29-/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem		0.940	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details BindingDB Entry DOI: 10.7270/Q2JM2FKJ
					More data for this Ligand-Target Pair
Estrogen receptor (Homo sapiens (Human))	BDBM443443 (US10654866, Example 8B | US11117902, Example 8B | ...) Show SMILES Cc1cccc-2c1O[C@H](c1ccc(OCCN3CC(CF)C3)cc1)c1c-2cnc2cc(O)ccc12 |r| Show InChI InChI=1S/C29H27FN2O3/c1-18-3-2-4-23-25-15-31-26-13-21(33)7-10-24(26)27(25)29(35-28(18)23)20-5-8-22(9-6-20)34-12-11-32-16-19(14-30)17-32/h2-10,13,15,19,29,33H,11-12,14,16-17H2,1H3/t29-/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	0.940	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Eli Lilly and Company US Patent					Assay Description Run the competition binding assay in a buffer containing 50 mM HEPES, pH 7.5, 1.5 mM EDTA, 150 mM NaCl, 10% glycerol, 1 mg/mL ovalbumin, and 5 mM DTT...				US Patent US10654866 (2020) BindingDB Entry DOI: 10.7270/Q2D50R05
					More data for this Ligand-Target Pair
Estrogen receptor (Homo sapiens (Human))	BDBM443443 (US10654866, Example 8B | US11117902, Example 8B | ...) Show SMILES Cc1cccc-2c1O[C@H](c1ccc(OCCN3CC(CF)C3)cc1)c1c-2cnc2cc(O)ccc12 |r| Show InChI InChI=1S/C29H27FN2O3/c1-18-3-2-4-23-25-15-31-26-13-21(33)7-10-24(26)27(25)29(35-28(18)23)20-5-8-22(9-6-20)34-12-11-32-16-19(14-30)17-32/h2-10,13,15,19,29,33H,11-12,14,16-17H2,1H3/t29-/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	0.940	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The purpose of the following ER competition binding assays is to determine the affinity of a test compound against ERα (wild type), ERα (Y5...				Citation and Details BindingDB Entry DOI: 10.7270/Q22B926M
					More data for this Ligand-Target Pair
Estrogen receptor (Homo sapiens (Human))	BDBM443448 (US10654866, Example 6B | US11117902, Example 6A | ...) Show SMILES Oc1ccc2c3[C@@H](Oc4c(F)cccc4-c3cnc2c1)c1ccc(OCCN2CC(CF)C2)cc1 |r| Show InChI InChI=1S/C28H24F2N2O3/c29-13-17-15-32(16-17)10-11-34-20-7-4-18(5-8-20)27-26-22-9-6-19(33)12-25(22)31-14-23(26)21-2-1-3-24(30)28(21)35-27/h1-9,12,14,17,27,33H,10-11,13,15-16H2/t27-/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	1.13	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Eli Lilly and Company US Patent					Assay Description Run the competition binding assay in a buffer containing 50 mM HEPES, pH 7.5, 1.5 mM EDTA, 150 mM NaCl, 10% glycerol, 1 mg/mL ovalbumin, and 5 mM DTT...				US Patent US10654866 (2020) BindingDB Entry DOI: 10.7270/Q2D50R05
					More data for this Ligand-Target Pair
Estrogen receptor (Homo sapiens (Human))	BDBM443448 (US10654866, Example 6B | US11117902, Example 6A | ...) Show SMILES Oc1ccc2c3[C@@H](Oc4c(F)cccc4-c3cnc2c1)c1ccc(OCCN2CC(CF)C2)cc1 |r| Show InChI InChI=1S/C28H24F2N2O3/c29-13-17-15-32(16-17)10-11-34-20-7-4-18(5-8-20)27-26-22-9-6-19(33)12-25(22)31-14-23(26)21-2-1-3-24(30)28(21)35-27/h1-9,12,14,17,27,33H,10-11,13,15-16H2/t27-/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem		1.13	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details BindingDB Entry DOI: 10.7270/Q2JM2FKJ
					More data for this Ligand-Target Pair
Estrogen receptor (Homo sapiens (Human))	BDBM443447 (US10654866, Example 6A | US11117902, Example 6B | ...) Show SMILES Oc1ccc2c3[C@H](Oc4c(F)cccc4-c3cnc2c1)c1ccc(OCCN2CC(CF)C2)cc1 |r| Show InChI InChI=1S/C28H24F2N2O3/c29-13-17-15-32(16-17)10-11-34-20-7-4-18(5-8-20)27-26-22-9-6-19(33)12-25(22)31-14-23(26)21-2-1-3-24(30)28(21)35-27/h1-9,12,14,17,27,33H,10-11,13,15-16H2/t27-/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	1.13	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The purpose of the following ER competition binding assays is to determine the affinity of a test compound against ERα (wild type), ERα (Y5...				Citation and Details BindingDB Entry DOI: 10.7270/Q22B926M
					More data for this Ligand-Target Pair
Estrogen receptor (Homo sapiens (Human))	BDBM443446 (US10654866, Example 5B | US11117902, Example 5A | ...) Show SMILES Oc1ccc2c3[C@@H](Oc4cc(F)ccc4-c3cnc2c1)c1ccc(OCCN2CC(CF)C2)cc1 |r| Show InChI InChI=1S/C28H24F2N2O3/c29-13-17-15-32(16-17)9-10-34-21-5-1-18(2-6-21)28-27-23-8-4-20(33)12-25(23)31-14-24(27)22-7-3-19(30)11-26(22)35-28/h1-8,11-12,14,17,28,33H,9-10,13,15-16H2/t28-/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	1.30	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Eli Lilly and Company US Patent					Assay Description Run the competition binding assay in a buffer containing 50 mM HEPES, pH 7.5, 1.5 mM EDTA, 150 mM NaCl, 10% glycerol, 1 mg/mL ovalbumin, and 5 mM DTT...				US Patent US10654866 (2020) BindingDB Entry DOI: 10.7270/Q2D50R05
					More data for this Ligand-Target Pair
Estrogen receptor (Homo sapiens (Human))	BDBM443446 (US10654866, Example 5B | US11117902, Example 5A | ...) Show SMILES Oc1ccc2c3[C@@H](Oc4cc(F)ccc4-c3cnc2c1)c1ccc(OCCN2CC(CF)C2)cc1 |r| Show InChI InChI=1S/C28H24F2N2O3/c29-13-17-15-32(16-17)9-10-34-21-5-1-18(2-6-21)28-27-23-8-4-20(33)12-25(23)31-14-24(27)22-7-3-19(30)11-26(22)35-28/h1-8,11-12,14,17,28,33H,9-10,13,15-16H2/t28-/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem		1.30	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details BindingDB Entry DOI: 10.7270/Q2JM2FKJ
					More data for this Ligand-Target Pair
Estrogen receptor (Homo sapiens (Human))	BDBM443445 (US10654866, Example 5A | US11117902, Example 5B | ...) Show SMILES Oc1ccc2c3[C@H](Oc4cc(F)ccc4-c3cnc2c1)c1ccc(OCCN2CC(CF)C2)cc1 |r| Show InChI InChI=1S/C28H24F2N2O3/c29-13-17-15-32(16-17)9-10-34-21-5-1-18(2-6-21)28-27-23-8-4-20(33)12-25(23)31-14-24(27)22-7-3-19(30)11-26(22)35-28/h1-8,11-12,14,17,28,33H,9-10,13,15-16H2/t28-/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	1.30	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The purpose of the following ER competition binding assays is to determine the affinity of a test compound against ERα (wild type), ERα (Y5...				Citation and Details BindingDB Entry DOI: 10.7270/Q22B926M
					More data for this Ligand-Target Pair
Estrogen receptor (Homo sapiens (Human))	BDBM443440 (US10654866, Example 7 | US11634426, Example 7) Show SMILES Cc1ccc-2c(OC(c3ccc(OCCN4CC(CF)C4)cc3)c3c-2cnc2cc(O)ccc32)c1 Show InChI InChI=1S/C29H27FN2O3/c1-18-2-8-23-25-15-31-26-13-21(33)5-9-24(26)28(25)29(35-27(23)12-18)20-3-6-22(7-4-20)34-11-10-32-16-19(14-30)17-32/h2-9,12-13,15,19,29,33H,10-11,14,16-17H2,1H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	1.55	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Eli Lilly and Company US Patent					Assay Description Run the competition binding assay in a buffer containing 50 mM HEPES, pH 7.5, 1.5 mM EDTA, 150 mM NaCl, 10% glycerol, 1 mg/mL ovalbumin, and 5 mM DTT...				US Patent US10654866 (2020) BindingDB Entry DOI: 10.7270/Q2D50R05
					More data for this Ligand-Target Pair
Estrogen receptor (Homo sapiens (Human))	BDBM518852 (US11117902, Example 7) Show SMILES Oc1ccc2c(C(=O)c3ccc(OCCN4CC(CF)C4)cc3)c(cnc2c1)-c1cccc(c1F)C(F)(F)F Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	1.55	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The purpose of the following ER competition binding assays is to determine the affinity of a test compound against ERα (wild type), ERα (Y5...				Citation and Details BindingDB Entry DOI: 10.7270/Q22B926M
					More data for this Ligand-Target Pair
Estrogen receptor (Homo sapiens (Human))	BDBM443440 (US10654866, Example 7 | US11634426, Example 7) Show SMILES Cc1ccc-2c(OC(c3ccc(OCCN4CC(CF)C4)cc3)c3c-2cnc2cc(O)ccc32)c1 Show InChI InChI=1S/C29H27FN2O3/c1-18-2-8-23-25-15-31-26-13-21(33)5-9-24(26)28(25)29(35-27(23)12-18)20-3-6-22(7-4-20)34-11-10-32-16-19(14-30)17-32/h2-9,12-13,15,19,29,33H,10-11,14,16-17H2,1H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem		1.55	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details BindingDB Entry DOI: 10.7270/Q2JM2FKJ
					More data for this Ligand-Target Pair
Estrogen receptor (Homo sapiens (Human))	BDBM443432 (Racemic 5-(4-{2- [3-(fluoromethyl) azetidin-1- yl]...) Show SMILES Oc1ccc2c3C(Oc4c(cccc4C(F)(F)F)-c3cnc2c1)c1ccc(OCCN2CC(CF)C2)cc1 Show InChI InChI=1S/C29H24F4N2O3/c30-13-17-15-35(16-17)10-11-37-20-7-4-18(5-8-20)27-26-22-9-6-19(36)12-25(22)34-14-23(26)21-2-1-3-24(28(21)38-27)29(31,32)33/h1-9,12,14,17,27,36H,10-11,13,15-16H2	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	2.17	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Eli Lilly and Company US Patent					Assay Description Run the competition binding assay in a buffer containing 50 mM HEPES, pH 7.5, 1.5 mM EDTA, 150 mM NaCl, 10% glycerol, 1 mg/mL ovalbumin, and 5 mM DTT...				US Patent US10654866 (2020) BindingDB Entry DOI: 10.7270/Q2D50R05
					More data for this Ligand-Target Pair
Estrogen receptor (Homo sapiens (Human))	BDBM443432 (Racemic 5-(4-{2- [3-(fluoromethyl) azetidin-1- yl]...) Show SMILES Oc1ccc2c3C(Oc4c(cccc4C(F)(F)F)-c3cnc2c1)c1ccc(OCCN2CC(CF)C2)cc1 Show InChI InChI=1S/C29H24F4N2O3/c30-13-17-15-35(16-17)10-11-37-20-7-4-18(5-8-20)27-26-22-9-6-19(36)12-25(22)34-14-23(26)21-2-1-3-24(28(21)38-27)29(31,32)33/h1-9,12,14,17,27,36H,10-11,13,15-16H2	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem		2.17	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details BindingDB Entry DOI: 10.7270/Q2JM2FKJ
					More data for this Ligand-Target Pair
Estrogen receptor (Homo sapiens (Human))	BDBM443432 (Racemic 5-(4-{2- [3-(fluoromethyl) azetidin-1- yl]...) Show SMILES Oc1ccc2c3C(Oc4c(cccc4C(F)(F)F)-c3cnc2c1)c1ccc(OCCN2CC(CF)C2)cc1 Show InChI InChI=1S/C29H24F4N2O3/c30-13-17-15-35(16-17)10-11-37-20-7-4-18(5-8-20)27-26-22-9-6-19(36)12-25(22)34-14-23(26)21-2-1-3-24(28(21)38-27)29(31,32)33/h1-9,12,14,17,27,36H,10-11,13,15-16H2	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	2.17	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The purpose of the following ER competition binding assays is to determine the affinity of a test compound against ERα (wild type), ERα (Y5...				Citation and Details BindingDB Entry DOI: 10.7270/Q22B926M
					More data for this Ligand-Target Pair
Estrogen receptor [Y537S] (Homo sapiens (Human))	BDBM443444 (US10654866, Example 4B | US11117902, Example 4A | ...) Show SMILES Oc1ccc2c3[C@@H](Oc4c(Cl)cccc4-c3cnc2c1)c1ccc(OCCN2CC(CF)C2)cc1 |r| Show InChI InChI=1S/C28H24ClFN2O3/c29-24-3-1-2-21-23-14-31-25-12-19(33)6-9-22(25)26(23)27(35-28(21)24)18-4-7-20(8-5-18)34-11-10-32-15-17(13-30)16-32/h1-9,12,14,17,27,33H,10-11,13,15-16H2/t27-/m0/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem		2.34	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details BindingDB Entry DOI: 10.7270/Q2JM2FKJ
					More data for this Ligand-Target Pair
Estrogen receptor [Y537S] (Homo sapiens (Human))	BDBM443437 (US10654866, Example 4A | US11117902, Example 4B | ...) Show SMILES Oc1ccc2c3[C@H](Oc4c(Cl)cccc4-c3cnc2c1)c1ccc(OCCN2CC(CF)C2)cc1 |r| Show InChI InChI=1S/C28H24ClFN2O3/c29-24-3-1-2-21-23-14-31-25-12-19(33)6-9-22(25)26(23)27(35-28(21)24)18-4-7-20(8-5-18)34-11-10-32-15-17(13-30)16-32/h1-9,12,14,17,27,33H,10-11,13,15-16H2/t27-/m1/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	2.34	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The purpose of the following ER competition binding assays is to determine the affinity of a test compound against ERα (wild type), ERα (Y5...				Citation and Details BindingDB Entry DOI: 10.7270/Q22B926M
					More data for this Ligand-Target Pair
Estrogen receptor [Y537S] (Homo sapiens (Human))	BDBM443444 (US10654866, Example 4B | US11117902, Example 4A | ...) Show SMILES Oc1ccc2c3[C@@H](Oc4c(Cl)cccc4-c3cnc2c1)c1ccc(OCCN2CC(CF)C2)cc1 |r| Show InChI InChI=1S/C28H24ClFN2O3/c29-24-3-1-2-21-23-14-31-25-12-19(33)6-9-22(25)26(23)27(35-28(21)24)18-4-7-20(8-5-18)34-11-10-32-15-17(13-30)16-32/h1-9,12,14,17,27,33H,10-11,13,15-16H2/t27-/m0/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	2.34	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Eli Lilly and Company US Patent					Assay Description Run the competition binding assay in a buffer containing 50 mM HEPES, pH 7.5, 1.5 mM EDTA, 150 mM NaCl, 10% glycerol, 1 mg/mL ovalbumin, and 5 mM DTT...				US Patent US10654866 (2020) BindingDB Entry DOI: 10.7270/Q2D50R05
					More data for this Ligand-Target Pair
Estrogen receptor (Homo sapiens (Human))	BDBM443435 (US10654866, Example 3 | US10654866, Example 3A | U...) Show SMILES Oc1ccc2c3C(Oc4cc(Cl)ccc4-c3cnc2c1)c1ccc(OCCN2CC(CF)C2)cc1 Show InChI InChI=1S/C28H24ClFN2O3/c29-19-3-7-22-24-14-31-25-12-20(33)4-8-23(25)27(24)28(35-26(22)11-19)18-1-5-21(6-2-18)34-10-9-32-15-17(13-30)16-32/h1-8,11-12,14,17,28,33H,9-10,13,15-16H2	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	2.36	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The purpose of the following ER competition binding assays is to determine the affinity of a test compound against ERα (wild type), ERα (Y5...				Citation and Details BindingDB Entry DOI: 10.7270/Q22B926M
					More data for this Ligand-Target Pair
Estrogen receptor (Homo sapiens (Human))	BDBM443435 (US10654866, Example 3 | US10654866, Example 3A | U...) Show SMILES Oc1ccc2c3C(Oc4cc(Cl)ccc4-c3cnc2c1)c1ccc(OCCN2CC(CF)C2)cc1 Show InChI InChI=1S/C28H24ClFN2O3/c29-19-3-7-22-24-14-31-25-12-20(33)4-8-23(25)27(24)28(35-26(22)11-19)18-1-5-21(6-2-18)34-10-9-32-15-17(13-30)16-32/h1-8,11-12,14,17,28,33H,9-10,13,15-16H2	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	2.36	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Eli Lilly and Company US Patent					Assay Description Run the competition binding assay in a buffer containing 50 mM HEPES, pH 7.5, 1.5 mM EDTA, 150 mM NaCl, 10% glycerol, 1 mg/mL ovalbumin, and 5 mM DTT...				US Patent US10654866 (2020) BindingDB Entry DOI: 10.7270/Q2D50R05
					More data for this Ligand-Target Pair
Estrogen receptor (Homo sapiens (Human))	BDBM443435 (US10654866, Example 3 | US10654866, Example 3A | U...) Show SMILES Oc1ccc2c3C(Oc4cc(Cl)ccc4-c3cnc2c1)c1ccc(OCCN2CC(CF)C2)cc1 Show InChI InChI=1S/C28H24ClFN2O3/c29-19-3-7-22-24-14-31-25-12-20(33)4-8-23(25)27(24)28(35-26(22)11-19)18-1-5-21(6-2-18)34-10-9-32-15-17(13-30)16-32/h1-8,11-12,14,17,28,33H,9-10,13,15-16H2	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem		2.36	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details BindingDB Entry DOI: 10.7270/Q2JM2FKJ
					More data for this Ligand-Target Pair
Estrogen receptor [Y537S] (Homo sapiens (Human))	BDBM443429 (US10654866, Example 1A | US11117902, Example 1B | ...) Show SMILES Oc1ccc2c3[C@H](Oc4cc(ccc4-c3cnc2c1)C(F)(F)F)c1ccc(OCCN2CC(CF)C2)cc1 |r| Show InChI InChI=1S/C29H24F4N2O3/c30-13-17-15-35(16-17)9-10-37-21-5-1-18(2-6-21)28-27-23-8-4-20(36)12-25(23)34-14-24(27)22-7-3-19(29(31,32)33)11-26(22)38-28/h1-8,11-12,14,17,28,36H,9-10,13,15-16H2/t28-/m1/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem	US Patent	2.79	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The purpose of the following ER competition binding assays is to determine the affinity of a test compound against ERα (wild type), ERα (Y5...				Citation and Details BindingDB Entry DOI: 10.7270/Q22B926M
					More data for this Ligand-Target Pair
Estrogen receptor [Y537S] (Homo sapiens (Human))	BDBM443430 (US10654866, Example 1B | US11117902, Example 1A | ...) Show SMILES Oc1ccc2c3[C@@H](Oc4cc(ccc4-c3cnc2c1)C(F)(F)F)c1ccc(OCCN2CC(CF)C2)cc1 |r| Show InChI InChI=1S/C29H24F4N2O3/c30-13-17-15-35(16-17)9-10-37-21-5-1-18(2-6-21)28-27-23-8-4-20(36)12-25(23)34-14-24(27)22-7-3-19(29(31,32)33)11-26(22)38-28/h1-8,11-12,14,17,28,36H,9-10,13,15-16H2/t28-/m0/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem	US Patent	2.79	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Eli Lilly and Company US Patent					Assay Description Run the competition binding assay in a buffer containing 50 mM HEPES, pH 7.5, 1.5 mM EDTA, 150 mM NaCl, 10% glycerol, 1 mg/mL ovalbumin, and 5 mM DTT...				US Patent US10654866 (2020) BindingDB Entry DOI: 10.7270/Q2D50R05
					More data for this Ligand-Target Pair
Estrogen receptor [Y537S] (Homo sapiens (Human))	BDBM443449 (US10654866, Example 3B | US11117902, Example 3A | ...) Show SMILES Oc1ccc2c3[C@@H](Oc4cc(Cl)ccc4-c3cnc2c1)c1ccc(OCCN2CC(CF)C2)cc1 |r| Show InChI InChI=1S/C28H24ClFN2O3/c29-19-3-7-22-24-14-31-25-12-20(33)4-8-23(25)27(24)28(35-26(22)11-19)18-1-5-21(6-2-18)34-10-9-32-15-17(13-30)16-32/h1-8,11-12,14,17,28,33H,9-10,13,15-16H2/t28-/m0/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem		2.79	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details BindingDB Entry DOI: 10.7270/Q2JM2FKJ
					More data for this Ligand-Target Pair
Estrogen receptor [Y537S] (Homo sapiens (Human))	BDBM443430 (US10654866, Example 1B | US11117902, Example 1A | ...) Show SMILES Oc1ccc2c3[C@@H](Oc4cc(ccc4-c3cnc2c1)C(F)(F)F)c1ccc(OCCN2CC(CF)C2)cc1 |r| Show InChI InChI=1S/C29H24F4N2O3/c30-13-17-15-35(16-17)9-10-37-21-5-1-18(2-6-21)28-27-23-8-4-20(36)12-25(23)34-14-24(27)22-7-3-19(29(31,32)33)11-26(22)38-28/h1-8,11-12,14,17,28,36H,9-10,13,15-16H2/t28-/m0/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem		2.79	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details BindingDB Entry DOI: 10.7270/Q2JM2FKJ
					More data for this Ligand-Target Pair
Estrogen receptor [Y537S] (Homo sapiens (Human))	BDBM443449 (US10654866, Example 3B | US11117902, Example 3A | ...) Show SMILES Oc1ccc2c3[C@@H](Oc4cc(Cl)ccc4-c3cnc2c1)c1ccc(OCCN2CC(CF)C2)cc1 |r| Show InChI InChI=1S/C28H24ClFN2O3/c29-19-3-7-22-24-14-31-25-12-20(33)4-8-23(25)27(24)28(35-26(22)11-19)18-1-5-21(6-2-18)34-10-9-32-15-17(13-30)16-32/h1-8,11-12,14,17,28,33H,9-10,13,15-16H2/t28-/m0/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	2.79	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Eli Lilly and Company US Patent					Assay Description Run the competition binding assay in a buffer containing 50 mM HEPES, pH 7.5, 1.5 mM EDTA, 150 mM NaCl, 10% glycerol, 1 mg/mL ovalbumin, and 5 mM DTT...				US Patent US10654866 (2020) BindingDB Entry DOI: 10.7270/Q2D50R05
					More data for this Ligand-Target Pair
Estrogen receptor [Y537S] (Homo sapiens (Human))	BDBM518821 (US11117902, Example 3B | US11634426, Example 3A) Show SMILES Oc1ccc2c3[C@H](Oc4cc(Cl)ccc4-c3cnc2c1)c1ccc(OCCN2CC(CF)C2)cc1 |r| Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	2.79	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The purpose of the following ER competition binding assays is to determine the affinity of a test compound against ERα (wild type), ERα (Y5...				Citation and Details BindingDB Entry DOI: 10.7270/Q22B926M
					More data for this Ligand-Target Pair
Estrogen receptor (Homo sapiens (Human))	BDBM443438 (US10654866, Example 5 | US11117902, Example 5 | US...) Show SMILES Oc1ccc2c3C(Oc4cc(F)ccc4-c3cnc2c1)c1ccc(OCCN2CC(CF)C2)cc1 Show InChI InChI=1S/C28H24F2N2O3/c29-13-17-15-32(16-17)9-10-34-21-5-1-18(2-6-21)28-27-23-8-4-20(33)12-25(23)31-14-24(27)22-7-3-19(30)11-26(22)35-28/h1-8,11-12,14,17,28,33H,9-10,13,15-16H2	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem		2.82	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details BindingDB Entry DOI: 10.7270/Q2JM2FKJ
					More data for this Ligand-Target Pair
Estrogen receptor (Homo sapiens (Human))	BDBM443438 (US10654866, Example 5 | US11117902, Example 5 | US...) Show SMILES Oc1ccc2c3C(Oc4cc(F)ccc4-c3cnc2c1)c1ccc(OCCN2CC(CF)C2)cc1 Show InChI InChI=1S/C28H24F2N2O3/c29-13-17-15-32(16-17)9-10-34-21-5-1-18(2-6-21)28-27-23-8-4-20(33)12-25(23)31-14-24(27)22-7-3-19(30)11-26(22)35-28/h1-8,11-12,14,17,28,33H,9-10,13,15-16H2	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	2.82	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Eli Lilly and Company US Patent					Assay Description Run the competition binding assay in a buffer containing 50 mM HEPES, pH 7.5, 1.5 mM EDTA, 150 mM NaCl, 10% glycerol, 1 mg/mL ovalbumin, and 5 mM DTT...				US Patent US10654866 (2020) BindingDB Entry DOI: 10.7270/Q2D50R05
					More data for this Ligand-Target Pair
Estrogen receptor (Homo sapiens (Human))	BDBM443438 (US10654866, Example 5 | US11117902, Example 5 | US...) Show SMILES Oc1ccc2c3C(Oc4cc(F)ccc4-c3cnc2c1)c1ccc(OCCN2CC(CF)C2)cc1 Show InChI InChI=1S/C28H24F2N2O3/c29-13-17-15-32(16-17)9-10-34-21-5-1-18(2-6-21)28-27-23-8-4-20(33)12-25(23)31-14-24(27)22-7-3-19(30)11-26(22)35-28/h1-8,11-12,14,17,28,33H,9-10,13,15-16H2	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	2.82	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The purpose of the following ER competition binding assays is to determine the affinity of a test compound against ERα (wild type), ERα (Y5...				Citation and Details BindingDB Entry DOI: 10.7270/Q22B926M
					More data for this Ligand-Target Pair
Estrogen receptor (Homo sapiens (Human))	BDBM443441 (US10654866, Example 8 | US11117902, Example 8 | US...) Show SMILES Cc1cccc-2c1OC(c1ccc(OCCN3CC(CF)C3)cc1)c1c-2cnc2cc(O)ccc12 Show InChI InChI=1S/C29H27FN2O3/c1-18-3-2-4-23-25-15-31-26-13-21(33)7-10-24(26)27(25)29(35-28(18)23)20-5-8-22(9-6-20)34-12-11-32-16-19(14-30)17-32/h2-10,13,15,19,29,33H,11-12,14,16-17H2,1H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem		3.20	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details BindingDB Entry DOI: 10.7270/Q2JM2FKJ
					More data for this Ligand-Target Pair
Estrogen receptor (Homo sapiens (Human))	BDBM443441 (US10654866, Example 8 | US11117902, Example 8 | US...) Show SMILES Cc1cccc-2c1OC(c1ccc(OCCN3CC(CF)C3)cc1)c1c-2cnc2cc(O)ccc12 Show InChI InChI=1S/C29H27FN2O3/c1-18-3-2-4-23-25-15-31-26-13-21(33)7-10-24(26)27(25)29(35-28(18)23)20-5-8-22(9-6-20)34-12-11-32-16-19(14-30)17-32/h2-10,13,15,19,29,33H,11-12,14,16-17H2,1H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	3.20	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Eli Lilly and Company US Patent					Assay Description Run the competition binding assay in a buffer containing 50 mM HEPES, pH 7.5, 1.5 mM EDTA, 150 mM NaCl, 10% glycerol, 1 mg/mL ovalbumin, and 5 mM DTT...				US Patent US10654866 (2020) BindingDB Entry DOI: 10.7270/Q2D50R05
					More data for this Ligand-Target Pair

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