Compile Data Set for Download or QSAR

Found 1111 hits with Last Name = 'colburn' and Initial = 'rw'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Delta-type opioid receptor (Rattus norvegicus (rat))	BDBM50154039 (2-Amino-1-[3-(5-bromo-4-phenyl-1H-imidazol-2-yl)-3...) Show SMILES N[C@@H](Cc1ccc(O)cc1)C(=O)N1Cc2ccccc2C[C@H]1c1nc(c(Br)[nH]1)-c1ccccc1 Show InChI InChI=1S/C27H25BrN4O2/c28-25-24(18-6-2-1-3-7-18)30-26(31-25)23-15-19-8-4-5-9-20(19)16-32(23)27(34)22(29)14-17-10-12-21(33)13-11-17/h1-13,22-23,33H,14-16,29H2,(H,30,31)/t22-,23-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	0.110	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Johnson & Johnson Pharmaceutical Research & Development Curated by ChEMBL					Assay Description Binding affinity for delta opioid receptor of rat brain				J Med Chem 47: 5009-20 (2004) Article DOI: 10.1021/jm030548r BindingDB Entry DOI: 10.7270/Q2H131GF
					More data for this Ligand-Target Pair
Mu-type opioid receptor (Rattus norvegicus (rat))	BDBM50017698 (4-(4-(4-chlorophenyl)-4-hydroxypiperidin-1-yl)-N,N...) Show SMILES CN(C)C(=O)C(CCN1CCC(O)(CC1)c1ccc(Cl)cc1)(c1ccccc1)c1ccccc1 Show InChI InChI=1S/C29H33ClN2O2/c1-31(2)27(33)29(24-9-5-3-6-10-24,25-11-7-4-8-12-25)19-22-32-20-17-28(34,18-21-32)23-13-15-26(30)16-14-23/h3-16,34H,17-22H2,1-2H3	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG PC cid PC sid UniChem Patents Similars	Article PubMed	0.160	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Johnson & Johnson Pharmaceutical Research & Development Curated by ChEMBL					Assay Description Binding affinity for Mu opioid receptor of rat brain				J Med Chem 47: 5009-20 (2004) Article DOI: 10.1021/jm030548r BindingDB Entry DOI: 10.7270/Q2H131GF
					More data for this Ligand-Target Pair
Mu-type opioid receptor (MOUSE)	BDBM50155124 (4-{Bromo-[(1S,5R)-8-furan-3-ylmethyl-8-aza-bicyclo...) Show SMILES CCNC(=O)c1ccc(cc1)C(\Br)=C1\C[C@@H]2CC[C@H](C1)N2Cc1ccoc1 |THB:21:20:13.14.19:17.16| Show InChI InChI=1S/C22H25BrN2O2/c1-2-24-22(26)17-5-3-16(4-6-17)21(23)18-11-19-7-8-20(12-18)25(19)13-15-9-10-27-14-15/h3-6,9-10,14,19-20H,2,7-8,11-13H2,1H3,(H,24,26)/b21-18-/t19-,20+/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	0.200	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Johnson and Johnson Pharmaceutical Research and Development Curated by ChEMBL					Assay Description Binding affinity against mu opioid receptor in mouse hot plate test				Bioorg Med Chem Lett 14: 5493-8 (2004) Article DOI: 10.1016/j.bmcl.2004.09.004 BindingDB Entry DOI: 10.7270/Q2X34WZV
					More data for this Ligand-Target Pair
Mu-type opioid receptor (MOUSE)	BDBM50155085 (CHEMBL362331 | N,N-Diethyl-4-[(8-phenethyl-8-aza-b...) Show SMILES [#6]-[#6]-[#7](-[#6]-[#6])-[#6](=O)-c1ccc(cc1)-[#6](=[#6]-1/[#6]-[#6]-2-[#6]-[#6]-[#6](-[#6]-1)-[#7]-2-[#6]-[#6]-c1ccccc1)\c1ccccc1 Show InChI InChI=1S/C33H38N2O/c1-3-34(4-2)33(36)28-17-15-27(16-18-28)32(26-13-9-6-10-14-26)29-23-30-19-20-31(24-29)35(30)22-21-25-11-7-5-8-12-25/h5-18,30-31H,3-4,19-24H2,1-2H3	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	0.260	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Johnson and Johnson Pharmaceutical Research and Development Curated by ChEMBL					Assay Description Binding affinity against mu opioid receptor in mouse hot plate test				Bioorg Med Chem Lett 14: 5493-8 (2004) Article DOI: 10.1016/j.bmcl.2004.09.004 BindingDB Entry DOI: 10.7270/Q2X34WZV
					More data for this Ligand-Target Pair
Delta-type opioid receptor (Rattus norvegicus (rat))	BDBM50154035 ((S)-2-amino-3-(4-hydroxyphenyl)-1-((S)-3-(5-methyl...) Show SMILES Cc1[nH]c(nc1-c1ccccc1)[C@@H]1Cc2ccccc2CN1C(=O)[C@@H](N)Cc1ccc(O)cc1 Show InChI InChI=1S/C28H28N4O2/c1-18-26(20-7-3-2-4-8-20)31-27(30-18)25-16-21-9-5-6-10-22(21)17-32(25)28(34)24(29)15-19-11-13-23(33)14-12-19/h2-14,24-25,33H,15-17,29H2,1H3,(H,30,31)/t24-,25-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	0.300	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Johnson & Johnson Pharmaceutical Research & Development Curated by ChEMBL					Assay Description Binding affinity for delta opioid receptor of rat brain				J Med Chem 47: 5009-20 (2004) Article DOI: 10.1021/jm030548r BindingDB Entry DOI: 10.7270/Q2H131GF
					More data for this Ligand-Target Pair
Delta-type opioid receptor (Rattus norvegicus (rat))	BDBM50154035 ((S)-2-amino-3-(4-hydroxyphenyl)-1-((S)-3-(5-methyl...) Show SMILES Cc1[nH]c(nc1-c1ccccc1)[C@@H]1Cc2ccccc2CN1C(=O)[C@@H](N)Cc1ccc(O)cc1 Show InChI InChI=1S/C28H28N4O2/c1-18-26(20-7-3-2-4-8-20)31-27(30-18)25-16-21-9-5-6-10-22(21)17-32(25)28(34)24(29)15-19-11-13-23(33)14-12-19/h2-14,24-25,33H,15-17,29H2,1H3,(H,30,31)/t24-,25-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	0.300	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Johnson & Johnson Pharmaceutical Research & Development Curated by ChEMBL					Assay Description Binding affinity for delta opioid receptor of rat brain				J Med Chem 47: 5009-20 (2004) Article DOI: 10.1021/jm030548r BindingDB Entry DOI: 10.7270/Q2H131GF
					More data for this Ligand-Target Pair
Mu-type opioid receptor (MOUSE)	BDBM50155068 (CHEMBL361720 | N-Ethyl-4-[(8-furan-3-ylmethyl-8-az...) Show SMILES [#6]-[#6]-[#7]-[#6](=O)-c1ccc(cc1)-[#6](=[#6]-1/[#6]-[#6]-2-[#6]-[#6]-[#6](-[#6]-1)-[#7]-2-[#6]-c1ccoc1)\c1ccc(-[#8])c(-[#8]-[#6])c1 Show InChI InChI=1S/C29H32N2O4/c1-3-30-29(33)21-6-4-20(5-7-21)28(22-8-11-26(32)27(16-22)34-2)23-14-24-9-10-25(15-23)31(24)17-19-12-13-35-18-19/h4-8,11-13,16,18,24-25,32H,3,9-10,14-15,17H2,1-2H3,(H,30,33)	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	0.590	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Johnson and Johnson Pharmaceutical Research and Development Curated by ChEMBL					Assay Description Binding affinity against mu opioid receptor in mouse hot plate test				Bioorg Med Chem Lett 14: 5493-8 (2004) Article DOI: 10.1016/j.bmcl.2004.09.004 BindingDB Entry DOI: 10.7270/Q2X34WZV
					More data for this Ligand-Target Pair
Mu-type opioid receptor (MOUSE)	BDBM50155120 (4-[(4-Acetylamino-phenyl)-(8-furan-3-ylmethyl-8-az...) Show SMILES [#6]-[#6]-[#7]-[#6](=O)-c1ccc(cc1)-[#6](=[#6]-1/[#6]-[#6]-2-[#6]-[#6]-[#6](-[#6]-1)-[#7]-2-[#6]-c1ccoc1)\c1ccc(-[#7]-[#6](-[#6])=O)cc1 Show InChI InChI=1S/C30H33N3O3/c1-3-31-30(35)24-6-4-22(5-7-24)29(23-8-10-26(11-9-23)32-20(2)34)25-16-27-12-13-28(17-25)33(27)18-21-14-15-36-19-21/h4-11,14-15,19,27-28H,3,12-13,16-18H2,1-2H3,(H,31,35)(H,32,34)	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	0.800	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Johnson and Johnson Pharmaceutical Research and Development Curated by ChEMBL					Assay Description Binding affinity against mu opioid receptor in mouse hot plate test				Bioorg Med Chem Lett 14: 5493-8 (2004) Article DOI: 10.1016/j.bmcl.2004.09.004 BindingDB Entry DOI: 10.7270/Q2X34WZV
					More data for this Ligand-Target Pair
Mu-type opioid receptor (MOUSE)	BDBM50155082 (CHEMBL363287 | N-Ethyl-4-[(8-furan-3-ylmethyl-8-az...) Show SMILES [#6]-[#6]-[#7]-[#6](=O)-c1ccc(cc1)-[#6](=[#6]-1\[#6]-[#6]-2-[#6]-[#6]-[#6](-[#6]-1)-[#7]-2-[#6]-c1ccoc1)\c1cccc(-[#6]-[#8])c1 Show InChI InChI=1S/C29H32N2O3/c1-2-30-29(33)23-8-6-22(7-9-23)28(24-5-3-4-20(14-24)18-32)25-15-26-10-11-27(16-25)31(26)17-21-12-13-34-19-21/h3-9,12-14,19,26-27,32H,2,10-11,15-18H2,1H3,(H,30,33)	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	0.810	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Johnson and Johnson Pharmaceutical Research and Development Curated by ChEMBL					Assay Description Binding affinity against mu opioid receptor in mouse hot plate test				Bioorg Med Chem Lett 14: 5493-8 (2004) Article DOI: 10.1016/j.bmcl.2004.09.004 BindingDB Entry DOI: 10.7270/Q2X34WZV
					More data for this Ligand-Target Pair
Delta-type opioid receptor (Rattus norvegicus (rat))	BDBM50154036 ((S)-2-amino-3-(4-hydroxyphenyl)-1-((S)-3-(4-phenyl...) Show SMILES N[C@@H](Cc1ccc(O)cc1)C(=O)N1Cc2ccccc2C[C@H]1c1nc(c[nH]1)-c1ccccc1 Show InChI InChI=1S/C27H26N4O2/c28-23(14-18-10-12-22(32)13-11-18)27(33)31-17-21-9-5-4-8-20(21)15-25(31)26-29-16-24(30-26)19-6-2-1-3-7-19/h1-13,16,23,25,32H,14-15,17,28H2,(H,29,30)/t23-,25-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	0.900	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Johnson & Johnson Pharmaceutical Research & Development Curated by ChEMBL					Assay Description Binding affinity for delta opioid receptor of rat brain				J Med Chem 47: 5009-20 (2004) Article DOI: 10.1021/jm030548r BindingDB Entry DOI: 10.7270/Q2H131GF
					More data for this Ligand-Target Pair
Mu-type opioid receptor (MOUSE)	BDBM50155069 (4-[Cyano-(8-furan-3-ylmethyl-8-aza-bicyclo[3.2.1]o...) Show SMILES [#6]-[#6]-[#7]-[#6](=O)-c1ccc(cc1)-[#6](\C#N)=[#6]-1/[#6]-[#6]-2-[#6]-[#6]-[#6](-[#6]-1)-[#7]-2-[#6]-c1ccoc1 Show InChI InChI=1S/C23H25N3O2/c1-2-25-23(27)18-5-3-17(4-6-18)22(13-24)19-11-20-7-8-21(12-19)26(20)14-16-9-10-28-15-16/h3-6,9-10,15,20-21H,2,7-8,11-12,14H2,1H3,(H,25,27)	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Johnson and Johnson Pharmaceutical Research and Development Curated by ChEMBL					Assay Description Binding affinity against mu opioid receptor in mouse hot plate test				Bioorg Med Chem Lett 14: 5493-8 (2004) Article DOI: 10.1016/j.bmcl.2004.09.004 BindingDB Entry DOI: 10.7270/Q2X34WZV
					More data for this Ligand-Target Pair
Mu-type opioid receptor (MOUSE)	BDBM50155096 (4-[Benzo[1,3]dioxol-5-yl-(8-furan-3-ylmethyl-8-aza...) Show SMILES [#6]-[#6]-[#7]-[#6](=O)-c1ccc(cc1)-[#6](=[#6]-1\[#6]-[#6]-2-[#6]-[#6]-[#6](-[#6]-1)-[#7]-2-[#6]-c1ccoc1)\c1ccc2-[#8]-[#6]-[#8]-c2c1 Show InChI InChI=1S/C29H30N2O4/c1-2-30-29(32)21-5-3-20(4-6-21)28(22-7-10-26-27(15-22)35-18-34-26)23-13-24-8-9-25(14-23)31(24)16-19-11-12-33-17-19/h3-7,10-12,15,17,24-25H,2,8-9,13-14,16,18H2,1H3,(H,30,32)	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.10	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Johnson and Johnson Pharmaceutical Research and Development Curated by ChEMBL					Assay Description Binding affinity against mu opioid receptor in mouse hot plate test				Bioorg Med Chem Lett 14: 5493-8 (2004) Article DOI: 10.1016/j.bmcl.2004.09.004 BindingDB Entry DOI: 10.7270/Q2X34WZV
					More data for this Ligand-Target Pair
Mu-type opioid receptor (MOUSE)	BDBM50155119 (4-[(3-Acetylamino-phenyl)-(8-furan-3-ylmethyl-8-az...) Show SMILES [#6]-[#6]-[#7]-[#6](=O)-c1ccc(cc1)-[#6](=[#6]-1/[#6]-[#6]-2-[#6]-[#6]-[#6](-[#6]-1)-[#7]-2-[#6]-c1ccoc1)\c1cccc(-[#7]-[#6](-[#6])=O)c1 Show InChI InChI=1S/C30H33N3O3/c1-3-31-30(35)23-9-7-22(8-10-23)29(24-5-4-6-26(15-24)32-20(2)34)25-16-27-11-12-28(17-25)33(27)18-21-13-14-36-19-21/h4-10,13-15,19,27-28H,3,11-12,16-18H2,1-2H3,(H,31,35)(H,32,34)	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.20	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Johnson and Johnson Pharmaceutical Research and Development Curated by ChEMBL					Assay Description Binding affinity against mu opioid receptor in mouse hot plate test				Bioorg Med Chem Lett 14: 5493-8 (2004) Article DOI: 10.1016/j.bmcl.2004.09.004 BindingDB Entry DOI: 10.7270/Q2X34WZV
					More data for this Ligand-Target Pair
Mu-type opioid receptor (MOUSE)	BDBM50155076 (CHEMBL186530 | N-Ethyl-4-[(8-furan-3-ylmethyl-8-az...) Show SMILES [#6]-[#6]-[#7]-[#6](=O)-c1ccc(cc1)-[#6](=[#6]-1/[#6]-[#6]-2-[#6]-[#6]-[#6](-[#6]-1)-[#7]-2-[#6]-c1ccoc1)\c1cccnc1 Show InChI InChI=1S/C27H29N3O2/c1-2-29-27(31)21-7-5-20(6-8-21)26(22-4-3-12-28-16-22)23-14-24-9-10-25(15-23)30(24)17-19-11-13-32-18-19/h3-8,11-13,16,18,24-25H,2,9-10,14-15,17H2,1H3,(H,29,31)	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.20	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Johnson and Johnson Pharmaceutical Research and Development Curated by ChEMBL					Assay Description Binding affinity against mu opioid receptor in mouse hot plate test				Bioorg Med Chem Lett 14: 5493-8 (2004) Article DOI: 10.1016/j.bmcl.2004.09.004 BindingDB Entry DOI: 10.7270/Q2X34WZV
					More data for this Ligand-Target Pair
Mu-type opioid receptor (MOUSE)	BDBM50155112 (1N-ethyl-4-{4-carbamoylphenyl[8-(3-furylmethyl)-8-...) Show SMILES [#6]-[#6]-[#7]-[#6](=O)-c1ccc(cc1)-[#6](=[#6]-1/[#6]-[#6]-2-[#6]-[#6]-[#6](-[#6]-1)-[#7]-2-[#6]-c1ccoc1)\c1ccc(cc1)-[#6](-[#7])=O Show InChI InChI=1S/C29H31N3O3/c1-2-31-29(34)23-9-5-21(6-10-23)27(20-3-7-22(8-4-20)28(30)33)24-15-25-11-12-26(16-24)32(25)17-19-13-14-35-18-19/h3-10,13-14,18,25-26H,2,11-12,15-17H2,1H3,(H2,30,33)(H,31,34)	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.30	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Johnson and Johnson Pharmaceutical Research and Development Curated by ChEMBL					Assay Description Binding affinity against mu opioid receptor in mouse hot plate test				Bioorg Med Chem Lett 14: 5493-8 (2004) Article DOI: 10.1016/j.bmcl.2004.09.004 BindingDB Entry DOI: 10.7270/Q2X34WZV
					More data for this Ligand-Target Pair
Mu-type opioid receptor (MOUSE)	BDBM50155101 (4-[(3-Acetyl-phenyl)-(8-furan-3-ylmethyl-8-aza-bic...) Show SMILES [#6]-[#6]-[#7]-[#6](=O)-c1ccc(cc1)-[#6](=[#6]-1/[#6]-[#6]-2-[#6]-[#6]-[#6](-[#6]-1)-[#7]-2-[#6]-c1ccoc1)\c1cccc(c1)-[#6](-[#6])=O Show InChI InChI=1S/C30H32N2O3/c1-3-31-30(34)23-9-7-22(8-10-23)29(25-6-4-5-24(15-25)20(2)33)26-16-27-11-12-28(17-26)32(27)18-21-13-14-35-19-21/h4-10,13-15,19,27-28H,3,11-12,16-18H2,1-2H3,(H,31,34)	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.30	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Johnson and Johnson Pharmaceutical Research and Development Curated by ChEMBL					Assay Description Binding affinity against mu opioid receptor in mouse hot plate test				Bioorg Med Chem Lett 14: 5493-8 (2004) Article DOI: 10.1016/j.bmcl.2004.09.004 BindingDB Entry DOI: 10.7270/Q2X34WZV
					More data for this Ligand-Target Pair
Mu-type opioid receptor (MOUSE)	BDBM50155089 (4-[Benzo[1,3]dioxol-5-yl-(8-thiophen-3-ylmethyl-8-...) Show SMILES [#6]-[#6]-[#7]-[#6](=O)-c1ccc(cc1)-[#6](=[#6]-1/[#6]-[#6]-2-[#6]-[#6]-[#6](-[#6]-1)-[#7]-2-[#6]-c1ccsc1)\c1ccc2-[#8]-[#6]-[#8]-c2c1 Show InChI InChI=1S/C29H30N2O3S/c1-2-30-29(32)21-5-3-20(4-6-21)28(22-7-10-26-27(15-22)34-18-33-26)23-13-24-8-9-25(14-23)31(24)16-19-11-12-35-17-19/h3-7,10-12,15,17,24-25H,2,8-9,13-14,16,18H2,1H3,(H,30,32)	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.30	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Johnson and Johnson Pharmaceutical Research and Development Curated by ChEMBL					Assay Description Binding affinity against mu opioid receptor in mouse hot plate test				Bioorg Med Chem Lett 14: 5493-8 (2004) Article DOI: 10.1016/j.bmcl.2004.09.004 BindingDB Entry DOI: 10.7270/Q2X34WZV
					More data for this Ligand-Target Pair
Mu-type opioid receptor (MOUSE)	BDBM50155109 (4-[(2,6-Dimethyl-phenyl)-(8-furan-3-ylmethyl-8-aza...) Show SMILES [#6]-[#6]-[#7]-[#6](=O)-c1ccc(cc1)-[#6](=[#6]-1\[#6]-[#6]-2-[#6]-[#6]-[#6](-[#6]-1)-[#7]-2-[#6]-c1ccoc1)\c1c(-[#6])cccc1-[#6] Show InChI InChI=1S/C30H34N2O2/c1-4-31-30(33)24-10-8-23(9-11-24)29(28-20(2)6-5-7-21(28)3)25-16-26-12-13-27(17-25)32(26)18-22-14-15-34-19-22/h5-11,14-15,19,26-27H,4,12-13,16-18H2,1-3H3,(H,31,33)	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.40	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Johnson and Johnson Pharmaceutical Research and Development Curated by ChEMBL					Assay Description Binding affinity against mu opioid receptor in mouse hot plate test				Bioorg Med Chem Lett 14: 5493-8 (2004) Article DOI: 10.1016/j.bmcl.2004.09.004 BindingDB Entry DOI: 10.7270/Q2X34WZV
					More data for this Ligand-Target Pair
Mu-type opioid receptor (MOUSE)	BDBM50155077 (CHEMBL186183 | N-Ethyl-4-[(8-furan-3-ylmethyl-8-az...) Show SMILES [#6]-[#6]-[#7]-[#6](=O)-c1ccc(cc1)-[#6](=[#6]-1/[#6]-[#6]-2-[#6]-[#6]-[#6](-[#6]-1)-[#7]-2-[#6]-c1ccoc1)\c1ccc(cc1)-[#7+](-[#8-])=O Show InChI InChI=1S/C28H29N3O4/c1-2-29-28(32)22-5-3-20(4-6-22)27(21-7-9-24(10-8-21)31(33)34)23-15-25-11-12-26(16-23)30(25)17-19-13-14-35-18-19/h3-10,13-14,18,25-26H,2,11-12,15-17H2,1H3,(H,29,32)	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Johnson and Johnson Pharmaceutical Research and Development Curated by ChEMBL					Assay Description Binding affinity against mu opioid receptor in mouse hot plate test				Bioorg Med Chem Lett 14: 5493-8 (2004) Article DOI: 10.1016/j.bmcl.2004.09.004 BindingDB Entry DOI: 10.7270/Q2X34WZV
					More data for this Ligand-Target Pair
Mu-type opioid receptor (Rattus norvegicus (rat))	BDBM50154041 ((S)-2-amino-3-(4-hydroxyphenyl)-1-((S)-2-(5-methyl...) Show SMILES Cc1[nH]c(nc1-c1ccccc1)[C@@H]1CCCCN1C(=O)[C@@H](N)Cc1ccc(O)cc1 Show InChI InChI=1S/C24H28N4O2/c1-16-22(18-7-3-2-4-8-18)27-23(26-16)21-9-5-6-14-28(21)24(30)20(25)15-17-10-12-19(29)13-11-17/h2-4,7-8,10-13,20-21,29H,5-6,9,14-15,25H2,1H3,(H,26,27)/t20-,21-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	1.5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Johnson & Johnson Pharmaceutical Research & Development Curated by ChEMBL					Assay Description Binding affinity for Mu opioid receptor of rat brain				J Med Chem 47: 5009-20 (2004) Article DOI: 10.1021/jm030548r BindingDB Entry DOI: 10.7270/Q2H131GF
					More data for this Ligand-Target Pair
Mu-type opioid receptor (MOUSE)	BDBM50155064 (4-[(4-Acetyl-phenyl)-(8-furan-3-ylmethyl-8-aza-bic...) Show SMILES [#6]-[#6]-[#7]-[#6](=O)-c1ccc(cc1)-[#6](=[#6]-1/[#6]-[#6]-2-[#6]-[#6]-[#6](-[#6]-1)-[#7]-2-[#6]-c1ccoc1)\c1ccc(cc1)-[#6](-[#6])=O Show InChI InChI=1S/C30H32N2O3/c1-3-31-30(34)25-10-8-24(9-11-25)29(23-6-4-22(5-7-23)20(2)33)26-16-27-12-13-28(17-26)32(27)18-21-14-15-35-19-21/h4-11,14-15,19,27-28H,3,12-13,16-18H2,1-2H3,(H,31,34)	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.70	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Johnson and Johnson Pharmaceutical Research and Development Curated by ChEMBL					Assay Description Binding affinity against mu opioid receptor in mouse hot plate test				Bioorg Med Chem Lett 14: 5493-8 (2004) Article DOI: 10.1016/j.bmcl.2004.09.004 BindingDB Entry DOI: 10.7270/Q2X34WZV
					More data for this Ligand-Target Pair
Mu-type opioid receptor (MOUSE)	BDBM50155107 (CHEMBL185229 | N-Ethyl-4-[(4-fluoro-phenyl)-(8-fur...) Show SMILES [#6]-[#6]-[#7]-[#6](=O)-c1ccc(cc1)-[#6](=[#6]-1/[#6]-[#6]-2-[#6]-[#6]-[#6](-[#6]-1)-[#7]-2-[#6]-c1ccoc1)\c1ccc(F)cc1 Show InChI InChI=1S/C28H29FN2O2/c1-2-30-28(32)22-5-3-20(4-6-22)27(21-7-9-24(29)10-8-21)23-15-25-11-12-26(16-23)31(25)17-19-13-14-33-18-19/h3-10,13-14,18,25-26H,2,11-12,15-17H2,1H3,(H,30,32)	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.70	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Johnson and Johnson Pharmaceutical Research and Development Curated by ChEMBL					Assay Description Binding affinity against mu opioid receptor in mouse hot plate test				Bioorg Med Chem Lett 14: 5493-8 (2004) Article DOI: 10.1016/j.bmcl.2004.09.004 BindingDB Entry DOI: 10.7270/Q2X34WZV
					More data for this Ligand-Target Pair
Mu-type opioid receptor (MOUSE)	BDBM50000092 ((-)-(etorphine) | (-)-morphine | (1S,5R,13R,14S)-1...) Show SMILES CN1CC[C@@]23[C@H]4Oc5c2c(C[C@@H]1[C@@H]3C=C[C@@H]4O)ccc5O |r,c:16,TLB:13:12:8.9.10:3.2.1| Show InChI InChI=1S/C17H19NO3/c1-18-7-6-17-10-3-5-13(20)16(17)21-15-12(19)4-2-9(14(15)17)8-11(10)18/h2-5,10-11,13,16,19-20H,6-8H2,1H3/t10-,11+,13-,16-,17-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase CHEMBL DrugBank KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	PDB Article PubMed	1.80	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Johnson and Johnson Pharmaceutical Research and Development Curated by ChEMBL					Assay Description Binding affinity against mu opioid receptor in mouse hot plate test				Bioorg Med Chem Lett 14: 5493-8 (2004) Article DOI: 10.1016/j.bmcl.2004.09.004 BindingDB Entry DOI: 10.7270/Q2X34WZV
					More data for this Ligand-Target Pair				3D Structure (crystal)
Mu-type opioid receptor (MOUSE)	BDBM50155080 (4-[(3,5-Dimethyl-isoxazol-4-yl)-(8-furan-3-ylmethy...) Show SMILES [#6]-[#6]-[#7]-[#6](=O)-c1ccc(cc1)-[#6](\c1c(-[#6])noc1-[#6])=[#6]-1\[#6]-[#6]-2-[#6]-[#6]-[#6](-[#6]-1)-[#7]-2-[#6]-c1ccoc1 Show InChI InChI=1S/C27H31N3O3/c1-4-28-27(31)21-7-5-20(6-8-21)26(25-17(2)29-33-18(25)3)22-13-23-9-10-24(14-22)30(23)15-19-11-12-32-16-19/h5-8,11-12,16,23-24H,4,9-10,13-15H2,1-3H3,(H,28,31)	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	1.80	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Johnson and Johnson Pharmaceutical Research and Development Curated by ChEMBL					Assay Description Binding affinity against mu opioid receptor in mouse hot plate test				Bioorg Med Chem Lett 14: 5493-8 (2004) Article DOI: 10.1016/j.bmcl.2004.09.004 BindingDB Entry DOI: 10.7270/Q2X34WZV
					More data for this Ligand-Target Pair
Mu-type opioid receptor (MOUSE)	BDBM50155084 (CHEMBL434903 | N-Ethyl-4-[(8-furan-3-ylmethyl-8-az...) Show SMILES [#6]-[#6]-[#7]-[#6](=O)-c1ccc(cc1)-[#6](=[#6]-1/[#6]-[#6]-2-[#6]-[#6]-[#6](-[#6]-1)-[#7]-2-[#6]-c1ccoc1)\[#6]-1=[#6]-[#7](-[#8]-[#6])-[#6]=[#6]-[#6]1 |c:35,t:30| Show InChI InChI=1S/C28H33N3O3/c1-3-29-28(32)22-8-6-21(7-9-22)27(23-5-4-13-30(18-23)33-2)24-15-25-10-11-26(16-24)31(25)17-20-12-14-34-19-20/h4,6-9,12-14,18-19,25-26H,3,5,10-11,15-17H2,1-2H3,(H,29,32)	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.90	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Johnson and Johnson Pharmaceutical Research and Development Curated by ChEMBL					Assay Description Binding affinity against mu opioid receptor in mouse hot plate test				Bioorg Med Chem Lett 14: 5493-8 (2004) Article DOI: 10.1016/j.bmcl.2004.09.004 BindingDB Entry DOI: 10.7270/Q2X34WZV
					More data for this Ligand-Target Pair
Mu-type opioid receptor (MOUSE)	BDBM50155105 (4-[Bromo-(8-furan-3-ylmethyl-8-aza-bicyclo[3.2.1]o...) Show SMILES [#6]-[#6]-[#7]-[#6](=O)-c1ccc(cc1)-[#6](\Br)=[#6]-1/[#6]-[#6]-2-[#6]-[#6]-[#6](-[#6]-1)-[#7]-2-[#6]-c1ccoc1 Show InChI InChI=1S/C22H25BrN2O2/c1-2-24-22(26)17-5-3-16(4-6-17)21(23)18-11-19-7-8-20(12-18)25(19)13-15-9-10-27-14-15/h3-6,9-10,14,19-20H,2,7-8,11-13H2,1H3,(H,24,26)	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.90	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Johnson and Johnson Pharmaceutical Research and Development Curated by ChEMBL					Assay Description Binding affinity against mu opioid receptor in mouse hot plate test				Bioorg Med Chem Lett 14: 5493-8 (2004) Article DOI: 10.1016/j.bmcl.2004.09.004 BindingDB Entry DOI: 10.7270/Q2X34WZV
					More data for this Ligand-Target Pair
Mu-type opioid receptor (MOUSE)	BDBM50155103 (4-{(3-Acetyl-phenyl)-[8-(3-methyl-but-3-enyl)-8-az...) Show SMILES [#6]-[#6]-[#7]-[#6](=O)-c1ccc(cc1)-[#6](=[#6]-1/[#6]-[#6]-2-[#6]-[#6]-[#6](-[#6]-1)-[#7]-2-[#6]-[#6]-[#6](-[#6])=[#6])\c1cccc(c1)-[#6](-[#6])=O Show InChI InChI=1S/C30H36N2O2/c1-5-31-30(34)23-11-9-22(10-12-23)29(25-8-6-7-24(17-25)21(4)33)26-18-27-13-14-28(19-26)32(27)16-15-20(2)3/h6-12,17,27-28H,2,5,13-16,18-19H2,1,3-4H3,(H,31,34)	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.90	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Johnson and Johnson Pharmaceutical Research and Development Curated by ChEMBL					Assay Description Binding affinity against mu opioid receptor in mouse hot plate test				Bioorg Med Chem Lett 14: 5493-8 (2004) Article DOI: 10.1016/j.bmcl.2004.09.004 BindingDB Entry DOI: 10.7270/Q2X34WZV
					More data for this Ligand-Target Pair
Mu-type opioid receptor (MOUSE)	BDBM50155079 (CHEMBL361456 | N-Ethyl-4-[(8-furan-3-ylmethyl-8-az...) Show SMILES [#6]-[#6]-[#7]-[#6](=O)-c1ccc(cc1)-[#6](=[#6]-1/[#6]-[#6]-2-[#6]-[#6]-[#6](-[#6]-1)-[#7]-2-[#6]-c1ccoc1)\c1ccncc1 Show InChI InChI=1S/C27H29N3O2/c1-2-29-27(31)22-5-3-20(4-6-22)26(21-9-12-28-13-10-21)23-15-24-7-8-25(16-23)30(24)17-19-11-14-32-18-19/h3-6,9-14,18,24-25H,2,7-8,15-17H2,1H3,(H,29,31)	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	2.20	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Johnson and Johnson Pharmaceutical Research and Development Curated by ChEMBL					Assay Description Binding affinity against mu opioid receptor in mouse hot plate test				Bioorg Med Chem Lett 14: 5493-8 (2004) Article DOI: 10.1016/j.bmcl.2004.09.004 BindingDB Entry DOI: 10.7270/Q2X34WZV
					More data for this Ligand-Target Pair
Mu-type opioid receptor (MOUSE)	BDBM50155106 (4-{Cyano-[(1R,5S)-8-furan-3-ylmethyl-8-aza-bicyclo...) Show SMILES CCNC(=O)c1ccc(cc1)C(\C#N)=C1/C[C@@H]2CC[C@H](C1)N2Cc1ccoc1 |THB:22:21:14.20.15:17.18| Show InChI InChI=1S/C23H25N3O2/c1-2-25-23(27)18-5-3-17(4-6-18)22(13-24)19-11-20-7-8-21(12-19)26(20)14-16-9-10-28-15-16/h3-6,9-10,15,20-21H,2,7-8,11-12,14H2,1H3,(H,25,27)/b22-19-/t20-,21+/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	2.30	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Johnson and Johnson Pharmaceutical Research and Development Curated by ChEMBL					Assay Description Binding affinity against mu opioid receptor in mouse hot plate test				Bioorg Med Chem Lett 14: 5493-8 (2004) Article DOI: 10.1016/j.bmcl.2004.09.004 BindingDB Entry DOI: 10.7270/Q2X34WZV
					More data for this Ligand-Target Pair
Mu-type opioid receptor (MOUSE)	BDBM50155099 (CHEMBL185780 | N-Ethyl-4-[pyrazin-2-yl-(8-thiophen...) Show SMILES [#6]-[#6]-[#7]-[#6](=O)-c1ccc(cc1)-[#6](=[#6]-1\[#6]-[#6]-2-[#6]-[#6]-[#6](-[#6]-1)-[#7]-2-[#6]-c1ccsc1)\c1cnccn1 Show InChI InChI=1S/C26H28N4OS/c1-2-28-26(31)20-5-3-19(4-6-20)25(24-15-27-10-11-29-24)21-13-22-7-8-23(14-21)30(22)16-18-9-12-32-17-18/h3-6,9-12,15,17,22-23H,2,7-8,13-14,16H2,1H3,(H,28,31)	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	2.5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Johnson and Johnson Pharmaceutical Research and Development Curated by ChEMBL					Assay Description Binding affinity against mu opioid receptor in mouse hot plate test				Bioorg Med Chem Lett 14: 5493-8 (2004) Article DOI: 10.1016/j.bmcl.2004.09.004 BindingDB Entry DOI: 10.7270/Q2X34WZV
					More data for this Ligand-Target Pair
Mu-type opioid receptor (MOUSE)	BDBM50155070 (4-{Cyano-[(1S,5R)-8-furan-3-ylmethyl-8-aza-bicyclo...) Show SMILES CCNC(=O)c1ccc(cc1)C(\C#N)=C1\C[C@@H]2CC[C@H](C1)N2Cc1ccoc1 |THB:22:21:14.15.20:18.17| Show InChI InChI=1S/C23H25N3O2/c1-2-25-23(27)18-5-3-17(4-6-18)22(13-24)19-11-20-7-8-21(12-19)26(20)14-16-9-10-28-15-16/h3-6,9-10,15,20-21H,2,7-8,11-12,14H2,1H3,(H,25,27)/b22-19-/t20-,21+/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	2.60	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Johnson and Johnson Pharmaceutical Research and Development Curated by ChEMBL					Assay Description Binding affinity against mu opioid receptor in mouse hot plate test				Bioorg Med Chem Lett 14: 5493-8 (2004) Article DOI: 10.1016/j.bmcl.2004.09.004 BindingDB Entry DOI: 10.7270/Q2X34WZV
					More data for this Ligand-Target Pair
Mu-type opioid receptor (MOUSE)	BDBM50155100 (4-[(3-Amino-phenyl)-(8-furan-3-ylmethyl-8-aza-bicy...) Show SMILES [#6]-[#6]-[#7]-[#6](=O)-c1ccc(cc1)-[#6](=[#6]-1/[#6]-[#6]-2-[#6]-[#6]-[#6](-[#6]-1)-[#7]-2-[#6]-c1ccoc1)\c1cccc(-[#7])c1 Show InChI InChI=1S/C28H31N3O2/c1-2-30-28(32)21-8-6-20(7-9-21)27(22-4-3-5-24(29)14-22)23-15-25-10-11-26(16-23)31(25)17-19-12-13-33-18-19/h3-9,12-14,18,25-26H,2,10-11,15-17,29H2,1H3,(H,30,32)	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	2.60	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Johnson and Johnson Pharmaceutical Research and Development Curated by ChEMBL					Assay Description Binding affinity against mu opioid receptor in mouse hot plate test				Bioorg Med Chem Lett 14: 5493-8 (2004) Article DOI: 10.1016/j.bmcl.2004.09.004 BindingDB Entry DOI: 10.7270/Q2X34WZV
					More data for this Ligand-Target Pair
Mu-type opioid receptor (MOUSE)	BDBM50155122 (4-{(3-Acetyl-phenyl)-[(1R,5S)-8-(3-methyl-but-3-en...) Show SMILES CCNC(=O)c1ccc(cc1)C(=C1\C[C@@H]2CC[C@H](C1)N2CCC(C)=C)\c1cccc(c1)C(C)=O |THB:20:19:12.13.18:16.15| Show InChI InChI=1S/C30H36N2O2/c1-5-31-30(34)23-11-9-22(10-12-23)29(25-8-6-7-24(17-25)21(4)33)26-18-27-13-14-28(19-26)32(27)16-15-20(2)3/h6-12,17,27-28H,2,5,13-16,18-19H2,1,3-4H3,(H,31,34)/b29-26-/t27-,28+/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	2.80	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Johnson and Johnson Pharmaceutical Research and Development Curated by ChEMBL					Assay Description Binding affinity against mu opioid receptor in mouse hot plate test				Bioorg Med Chem Lett 14: 5493-8 (2004) Article DOI: 10.1016/j.bmcl.2004.09.004 BindingDB Entry DOI: 10.7270/Q2X34WZV
					More data for this Ligand-Target Pair
Mu-type opioid receptor (MOUSE)	BDBM50155063 (3-{3-[(4-Ethylcarbamoyl-phenyl)-(8-furan-3-ylmethy...) Show SMILES [#6]-[#6]-[#7]-[#6](=O)-c1ccc(cc1)-[#6](=[#6]-1\[#6]-[#6]-2-[#6]-[#6]-[#6](-[#6]-1)-[#7]-2-[#6]-c1ccoc1)\c1cccc(-[#6]-[#6]-[#6](-[#8])=O)c1 Show InChI InChI=1S/C31H34N2O4/c1-2-32-31(36)24-9-7-23(8-10-24)30(25-5-3-4-21(16-25)6-13-29(34)35)26-17-27-11-12-28(18-26)33(27)19-22-14-15-37-20-22/h3-5,7-10,14-16,20,27-28H,2,6,11-13,17-19H2,1H3,(H,32,36)(H,34,35)	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Johnson and Johnson Pharmaceutical Research and Development Curated by ChEMBL					Assay Description Binding affinity against mu opioid receptor in mouse hot plate test				Bioorg Med Chem Lett 14: 5493-8 (2004) Article DOI: 10.1016/j.bmcl.2004.09.004 BindingDB Entry DOI: 10.7270/Q2X34WZV
					More data for this Ligand-Target Pair
Mu-type opioid receptor (MOUSE)	BDBM50155094 (CHEMBL186041 | N-Ethyl-4-[(8-furan-3-ylmethyl-8-az...) Show SMILES [#6]-[#6]-[#7]-[#6](=O)-c1ccc(cc1)-[#6](=[#6]-1\[#6]-[#6]-2-[#6]-[#6]-[#6](-[#6]-1)-[#7]-2-[#6]-c1ccoc1)\c1ccc(cc1)S([#6])(=O)=O Show InChI InChI=1S/C29H32N2O4S/c1-3-30-29(32)23-6-4-21(5-7-23)28(22-8-12-27(13-9-22)36(2,33)34)24-16-25-10-11-26(17-24)31(25)18-20-14-15-35-19-20/h4-9,12-15,19,25-26H,3,10-11,16-18H2,1-2H3,(H,30,32)	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	3.10	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Johnson and Johnson Pharmaceutical Research and Development Curated by ChEMBL					Assay Description Binding affinity against mu opioid receptor in mouse hot plate test				Bioorg Med Chem Lett 14: 5493-8 (2004) Article DOI: 10.1016/j.bmcl.2004.09.004 BindingDB Entry DOI: 10.7270/Q2X34WZV
					More data for this Ligand-Target Pair
Mu-type opioid receptor (MOUSE)	BDBM50155086 (4-[(3-Cyano-phenyl)-(8-furan-3-ylmethyl-8-aza-bicy...) Show SMILES [#6]-[#6]-[#7]-[#6](=O)-c1ccc(cc1)-[#6](=[#6]-1\[#6]-[#6]-2-[#6]-[#6]-[#6](-[#6]-1)-[#7]-2-[#6]-c1ccoc1)\c1cccc(c1)C#N Show InChI InChI=1S/C29H29N3O2/c1-2-31-29(33)23-8-6-22(7-9-23)28(24-5-3-4-20(14-24)17-30)25-15-26-10-11-27(16-25)32(26)18-21-12-13-34-19-21/h3-9,12-14,19,26-27H,2,10-11,15-16,18H2,1H3,(H,31,33)	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	3.30	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Johnson and Johnson Pharmaceutical Research and Development Curated by ChEMBL					Assay Description Binding affinity against mu opioid receptor in mouse hot plate test				Bioorg Med Chem Lett 14: 5493-8 (2004) Article DOI: 10.1016/j.bmcl.2004.09.004 BindingDB Entry DOI: 10.7270/Q2X34WZV
					More data for this Ligand-Target Pair
Mu-type opioid receptor (MOUSE)	BDBM50155111 (4-[(3-Acetylamino-phenyl)-(8-pyridin-2-ylmethyl-8-...) Show SMILES [#6]-[#6]-[#7]-[#6](=O)-c1ccc(cc1)-[#6](=[#6]-1\[#6]-[#6]-2-[#6]-[#6]-[#6](-[#6]-1)-[#7]-2-[#6]-c1ccccn1)\c1cccc(-[#7]-[#6](-[#6])=O)c1 Show InChI InChI=1S/C31H34N4O2/c1-3-32-31(37)23-12-10-22(11-13-23)30(24-7-6-9-26(17-24)34-21(2)36)25-18-28-14-15-29(19-25)35(28)20-27-8-4-5-16-33-27/h4-13,16-17,28-29H,3,14-15,18-20H2,1-2H3,(H,32,37)(H,34,36)	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	3.60	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Johnson and Johnson Pharmaceutical Research and Development Curated by ChEMBL					Assay Description Binding affinity against mu opioid receptor in mouse hot plate test				Bioorg Med Chem Lett 14: 5493-8 (2004) Article DOI: 10.1016/j.bmcl.2004.09.004 BindingDB Entry DOI: 10.7270/Q2X34WZV
					More data for this Ligand-Target Pair
Mu-type opioid receptor (MOUSE)	BDBM50155072 (CHEMBL187376 | N-Ethyl-4-[(3-fluoro-phenyl)-(8-fur...) Show SMILES [#6]-[#6]-[#7]-[#6](=O)-c1ccc(cc1)-[#6](=[#6]-1/[#6]-[#6]-2-[#6]-[#6]-[#6](-[#6]-1)-[#7]-2-[#6]-c1ccoc1)\c1cccc(F)c1 Show InChI InChI=1S/C28H29FN2O2/c1-2-30-28(32)21-8-6-20(7-9-21)27(22-4-3-5-24(29)14-22)23-15-25-10-11-26(16-23)31(25)17-19-12-13-33-18-19/h3-9,12-14,18,25-26H,2,10-11,15-17H2,1H3,(H,30,32)	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	3.70	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Johnson and Johnson Pharmaceutical Research and Development Curated by ChEMBL					Assay Description Binding affinity against mu opioid receptor in mouse hot plate test				Bioorg Med Chem Lett 14: 5493-8 (2004) Article DOI: 10.1016/j.bmcl.2004.09.004 BindingDB Entry DOI: 10.7270/Q2X34WZV
					More data for this Ligand-Target Pair
Mu-type opioid receptor (MOUSE)	BDBM50155075 (CHEMBL363677 | N-Ethyl-4-[(8-furan-3-ylmethyl-8-az...) Show SMILES [#6]-[#6]-[#7]-[#6](=O)-c1ccc(cc1)-[#6](=[#6]-1/[#6]-[#6]-2-[#6]-[#6]-[#6](-[#6]-1)-[#7]-2-[#6]-c1ccoc1)\c1cnc2ccccc2c1 Show InChI InChI=1S/C31H31N3O2/c1-2-32-31(35)23-9-7-22(8-10-23)30(26-15-24-5-3-4-6-29(24)33-18-26)25-16-27-11-12-28(17-25)34(27)19-21-13-14-36-20-21/h3-10,13-15,18,20,27-28H,2,11-12,16-17,19H2,1H3,(H,32,35)	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Johnson and Johnson Pharmaceutical Research and Development Curated by ChEMBL					Assay Description Binding affinity against mu opioid receptor in mouse hot plate test				Bioorg Med Chem Lett 14: 5493-8 (2004) Article DOI: 10.1016/j.bmcl.2004.09.004 BindingDB Entry DOI: 10.7270/Q2X34WZV
					More data for this Ligand-Target Pair
B2 bradykinin receptor (Homo sapiens (Human))	BDBM50126226 (3-[5-(4-Cyano-benzoyl)-1-methyl-1H-pyrrol-2-yl]-N-...) Show SMILES CN(C(=O)CCc1ccc(C(=O)c2ccc(cc2)C#N)n1C)c1ccc(Cl)c(COc2cccc3ccc(C)nc23)c1Cl Show InChI InChI=1S/C34H28Cl2N4O3/c1-21-7-10-23-5-4-6-30(33(23)38-21)43-20-26-27(35)15-17-28(32(26)36)40(3)31(41)18-14-25-13-16-29(39(25)2)34(42)24-11-8-22(19-37)9-12-24/h4-13,15-17H,14,18,20H2,1-3H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Johnson & Johnson Pharmaceutical Research and Development Curated by ChEMBL					Assay Description Binding affinity towards human bradykinin receptor B2				Bioorg Med Chem Lett 13: 1341-4 (2003) BindingDB Entry DOI: 10.7270/Q2HM57T1
					More data for this Ligand-Target Pair
Mu-type opioid receptor (MOUSE)	BDBM50155121 (CHEMBL363265 | N-Ethyl-4-[(8-furan-3-ylmethyl-8-az...) Show SMILES [#6]-[#6]-[#7]-[#6](=O)-c1ccc(cc1)-[#6](=[#6]-1\[#6]-[#6]-2-[#6]-[#6]-[#6](-[#6]-1)-[#7]-2-[#6]-c1ccoc1)\[#6]-1=[#6]-[#7](-[#8])-[#6]=[#6]-[#6]1 |c:34,t:30| Show InChI InChI=1S/C27H31N3O3/c1-2-28-27(31)21-7-5-20(6-8-21)26(22-4-3-12-29(32)17-22)23-14-24-9-10-25(15-23)30(24)16-19-11-13-33-18-19/h3,5-8,11-13,17-18,24-25,32H,2,4,9-10,14-16H2,1H3,(H,28,31)	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	4.10	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Johnson and Johnson Pharmaceutical Research and Development Curated by ChEMBL					Assay Description Binding affinity against mu opioid receptor in mouse hot plate test				Bioorg Med Chem Lett 14: 5493-8 (2004) Article DOI: 10.1016/j.bmcl.2004.09.004 BindingDB Entry DOI: 10.7270/Q2X34WZV
					More data for this Ligand-Target Pair
Delta-type opioid receptor (Rattus norvegicus (rat))	BDBM50154042 (2-[2-Amino-3-(4-hydroxy-phenyl)-propionyl]-1,2,3,4...) Show SMILES N[C@@H](Cc1ccc(O)cc1)C(=O)N1Cc2ccccc2C[C@H]1C(=O)NCCc1ccccc1 Show InChI InChI=1S/C27H29N3O3/c28-24(16-20-10-12-23(31)13-11-20)27(33)30-18-22-9-5-4-8-21(22)17-25(30)26(32)29-15-14-19-6-2-1-3-7-19/h1-13,24-25,31H,14-18,28H2,(H,29,32)/t24-,25-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	5.20	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Johnson & Johnson Pharmaceutical Research & Development Curated by ChEMBL					Assay Description Binding affinity for delta opioid receptor of rat brain				J Med Chem 47: 5009-20 (2004) Article DOI: 10.1021/jm030548r BindingDB Entry DOI: 10.7270/Q2H131GF
					More data for this Ligand-Target Pair
Mu-type opioid receptor (MOUSE)	BDBM50155108 (CHEMBL185782 | N-Ethyl-4-[pyridin-2-yl-(8-thiophen...) Show SMILES [#6]-[#6]-[#7]-[#6](=O)-c1ccc(cc1)-[#6](=[#6]-1\[#6]-[#6]-2-[#6]-[#6]-[#6](-[#6]-1)-[#7]-2-[#6]-c1cccs1)\c1ccccn1 Show InChI InChI=1S/C27H29N3OS/c1-2-28-27(31)20-10-8-19(9-11-20)26(25-7-3-4-14-29-25)21-16-22-12-13-23(17-21)30(22)18-24-6-5-15-32-24/h3-11,14-15,22-23H,2,12-13,16-18H2,1H3,(H,28,31)	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	6	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Johnson and Johnson Pharmaceutical Research and Development Curated by ChEMBL					Assay Description Binding affinity against mu opioid receptor in mouse hot plate test				Bioorg Med Chem Lett 14: 5493-8 (2004) Article DOI: 10.1016/j.bmcl.2004.09.004 BindingDB Entry DOI: 10.7270/Q2X34WZV
					More data for this Ligand-Target Pair
Mu-type opioid receptor (MOUSE)	BDBM50155125 (CHEMBL184820 | N-Ethyl-4-{furan-2-yl-[8-(3-methyl-...) Show SMILES [#6]-[#6]-[#7]-[#6](=O)-c1ccc(cc1)-[#6](\c1ccco1)=[#6]-1/[#6]-[#6]-2-[#6]-[#6]-[#6](-[#6]-1)-[#7]-2-[#6]-[#6]-[#6](-[#6])=[#6] Show InChI InChI=1S/C26H32N2O2/c1-4-27-26(29)20-9-7-19(8-10-20)25(24-6-5-15-30-24)21-16-22-11-12-23(17-21)28(22)14-13-18(2)3/h5-10,15,22-23H,2,4,11-14,16-17H2,1,3H3,(H,27,29)	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	6.30	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Johnson and Johnson Pharmaceutical Research and Development Curated by ChEMBL					Assay Description Binding affinity against mu opioid receptor in mouse hot plate test				Bioorg Med Chem Lett 14: 5493-8 (2004) Article DOI: 10.1016/j.bmcl.2004.09.004 BindingDB Entry DOI: 10.7270/Q2X34WZV
					More data for this Ligand-Target Pair
Mu-type opioid receptor (MOUSE)	BDBM50155078 (1N,1N-dimethyl-4-{4-ethylcarbamoylphenyl[8-(3-fury...) Show SMILES [#6]-[#6]-[#7]-[#6](=O)-c1ccc(cc1)-[#6](=[#6]-1\[#6]-[#6]-2-[#6]-[#6]-[#6](-[#6]-1)-[#7]-2-[#6]-c1ccoc1)\c1ccc(cc1)-[#6](=O)-[#7](-[#6])-[#6] Show InChI InChI=1S/C31H35N3O3/c1-4-32-30(35)24-9-5-22(6-10-24)29(23-7-11-25(12-8-23)31(36)33(2)3)26-17-27-13-14-28(18-26)34(27)19-21-15-16-37-20-21/h5-12,15-16,20,27-28H,4,13-14,17-19H2,1-3H3,(H,32,35)	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	6.70	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Johnson and Johnson Pharmaceutical Research and Development Curated by ChEMBL					Assay Description Binding affinity against mu opioid receptor in mouse hot plate test				Bioorg Med Chem Lett 14: 5493-8 (2004) Article DOI: 10.1016/j.bmcl.2004.09.004 BindingDB Entry DOI: 10.7270/Q2X34WZV
					More data for this Ligand-Target Pair
Mu-type opioid receptor (MOUSE)	BDBM50155113 (CHEMBL187806 | N-Ethyl-4-[(8-furan-3-ylmethyl-8-az...) Show SMILES [#6]-[#6]-[#7]-[#6](=O)-c1ccc(cc1)-[#6](=[#6]-1/[#6]-[#6]-2-[#6]-[#6]-[#6](-[#6]-1)-[#7]-2-[#6]-c1ccoc1)\c1cncnc1 Show InChI InChI=1S/C26H28N4O2/c1-2-29-26(31)20-5-3-19(4-6-20)25(22-13-27-17-28-14-22)21-11-23-7-8-24(12-21)30(23)15-18-9-10-32-16-18/h3-6,9-10,13-14,16-17,23-24H,2,7-8,11-12,15H2,1H3,(H,29,31)	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	6.90	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Johnson and Johnson Pharmaceutical Research and Development Curated by ChEMBL					Assay Description Binding affinity against mu opioid receptor in mouse hot plate test				Bioorg Med Chem Lett 14: 5493-8 (2004) Article DOI: 10.1016/j.bmcl.2004.09.004 BindingDB Entry DOI: 10.7270/Q2X34WZV
					More data for this Ligand-Target Pair
Transient receptor potential cation channel subfamily V member 1 (Homo sapiens (Human))	BDBM50376255 (CHEMBL408401) Show SMILES CN(C1CCCCC1)c1ccc(cc1)C(=O)Nc1cnc2ccccc2c1 Show InChI InChI=1S/C23H25N3O/c1-26(20-8-3-2-4-9-20)21-13-11-17(12-14-21)23(27)25-19-15-18-7-5-6-10-22(18)24-16-19/h5-7,10-16,20H,2-4,8-9H2,1H3,(H,25,27)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	8	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Johnson& Johnson Pharmaceutical Research and Development Curated by ChEMBL					Assay Description Displacement of [3H]RTX from human TRPV1 receptor expressed in HEK293 cells				Bioorg Med Chem Lett 18: 2730-4 (2008) Article DOI: 10.1016/j.bmcl.2008.02.075 BindingDB Entry DOI: 10.7270/Q27H1KF6
					More data for this Ligand-Target Pair
Mu-type opioid receptor (MOUSE)	BDBM50155092 (4-{(3-Acetylamino-phenyl)-[8-(1H-imidazol-4-ylmeth...) Show SMILES CCNC(=O)c1ccc(cc1)C(=C1CC2CCC(C1)N2Cc1cnc[nH]1)c1cccc(NC(C)=O)c1 |(8.64,3.46,;7.32,4.22,;5.98,3.44,;4.63,4.2,;4.6,5.74,;3.31,3.44,;1.96,4.2,;.63,3.42,;.63,1.9,;1.96,1.12,;3.31,1.9,;-.7,1.12,;-.71,-.42,;-2.06,-1.17,;-2.06,-2.7,;-1.46,-1.59,;-.11,-1.59,;.58,-2.74,;.61,-1.2,;-.74,-3.5,;-.77,-5.03,;.55,-5.82,;1.95,-5.2,;2.97,-6.35,;2.18,-7.68,;.7,-7.34,;-2.02,1.9,;-2.02,3.44,;-3.35,4.2,;-4.69,3.44,;-4.69,1.9,;-6,1.14,;-6,-.38,;-4.69,-1.13,;-7.32,-1.13,;-3.35,1.12,)| Show InChI InChI=1S/C29H33N5O2/c1-3-31-29(36)21-9-7-20(8-10-21)28(22-5-4-6-24(13-22)33-19(2)35)23-14-26-11-12-27(15-23)34(26)17-25-16-30-18-32-25/h4-10,13,16,18,26-27H,3,11-12,14-15,17H2,1-2H3,(H,30,32)(H,31,36)(H,33,35)	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	9.40	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Johnson and Johnson Pharmaceutical Research and Development Curated by ChEMBL					Assay Description Binding affinity against mu opioid receptor in mouse hot plate test				Bioorg Med Chem Lett 14: 5493-8 (2004) Article DOI: 10.1016/j.bmcl.2004.09.004 BindingDB Entry DOI: 10.7270/Q2X34WZV
					More data for this Ligand-Target Pair
Mu-type opioid receptor (MOUSE)	BDBM50155118 (CHEMBL425713 | N-Ethyl-4-[(8-furan-3-ylmethyl-8-az...) Show SMILES [#6]-[#6]-[#7]-[#6](=O)-c1ccc(cc1)-[#6](=[#6]-1/[#6]-[#6]-2-[#6]-[#6]-[#6](-[#6]-1)-[#7]-2-[#6]-c1ccoc1)\c1cnccn1 Show InChI InChI=1S/C26H28N4O2/c1-2-28-26(31)20-5-3-19(4-6-20)25(24-15-27-10-11-29-24)21-13-22-7-8-23(14-21)30(22)16-18-9-12-32-17-18/h3-6,9-12,15,17,22-23H,2,7-8,13-14,16H2,1H3,(H,28,31)	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	9.90	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Johnson and Johnson Pharmaceutical Research and Development Curated by ChEMBL					Assay Description Binding affinity against mu opioid receptor in mouse hot plate test				Bioorg Med Chem Lett 14: 5493-8 (2004) Article DOI: 10.1016/j.bmcl.2004.09.004 BindingDB Entry DOI: 10.7270/Q2X34WZV
					More data for this Ligand-Target Pair
B2 bradykinin receptor (Homo sapiens (Human))	BDBM50126231 (2-[5-(4-Cyano-benzoyl)-1-ethyl-1H-pyrrol-2-yl]-N-[...) Show SMILES CCn1c(CC(=O)N(C)c2ccc(Cl)c(COc3cccc4ccc(C)nc34)c2Cl)ccc1C(=O)c1ccc(cc1)C#N Show InChI InChI=1S/C34H28Cl2N4O3/c1-4-40-25(14-16-29(40)34(42)24-12-9-22(19-37)10-13-24)18-31(41)39(3)28-17-15-27(35)26(32(28)36)20-43-30-7-5-6-23-11-8-21(2)38-33(23)30/h5-17H,4,18,20H2,1-3H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	10	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Johnson & Johnson Pharmaceutical Research and Development Curated by ChEMBL					Assay Description Binding affinity towards human bradykinin receptor B2				Bioorg Med Chem Lett 13: 1341-4 (2003) BindingDB Entry DOI: 10.7270/Q2HM57T1
					More data for this Ligand-Target Pair

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