Compile Data Set for Download or QSAR

Found 122 hits with Last Name = 'colle' and Initial = 'r'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Kappa-type opioid receptor (Cavia porcellus (domestic guinea pig))	BDBM50001107 (2-(3,4-Dichloro-phenyl)-1-(5-hydroxy-1-pyrrolidin-...) Show SMILES Oc1cccc2C(CN3CCCC3)N(CCc12)C(=O)Cc1ccc(Cl)c(Cl)c1 Show InChI InChI=1S/C22H24Cl2N2O2/c23-18-7-6-15(12-19(18)24)13-22(28)26-11-8-17-16(4-3-5-21(17)27)20(26)14-25-9-1-2-10-25/h3-7,12,20,27H,1-2,8-11,13-14H2	PDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	0.0900	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Zambeletti Research Laboratories Curated by ChEMBL					Assay Description Receptor binding affinity towards opioid receptor kappa				J Med Chem 35: 2970-8 (1992) BindingDB Entry DOI: 10.7270/Q2P26ZR7
					More data for this Ligand-Target Pair
Kappa-type opioid receptor (Cavia porcellus (domestic guinea pig))	BDBM50001108 (2-(3,4-Dichloro-phenyl)-1-(1-pyrrolidin-1-ylmethyl...) Show SMILES Clc1ccc(CC(=O)N2CCc3ccccc3C2CN2CCCC2)cc1Cl Show InChI InChI=1S/C22H24Cl2N2O/c23-19-8-7-16(13-20(19)24)14-22(27)26-12-9-17-5-1-2-6-18(17)21(26)15-25-10-3-4-11-25/h1-2,5-8,13,21H,3-4,9-12,14-15H2	PDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	0.200	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Zambeletti Research Laboratories Curated by ChEMBL					Assay Description Displacement of [3H]-BRL 52537 from opioid receptor kappa site in guinea pig				J Med Chem 34: 2624-33 (1991) BindingDB Entry DOI: 10.7270/Q2CV4GPX
					More data for this Ligand-Target Pair
Kappa-type opioid receptor (Cavia porcellus (domestic guinea pig))	BDBM50001108 (2-(3,4-Dichloro-phenyl)-1-(1-pyrrolidin-1-ylmethyl...) Show SMILES Clc1ccc(CC(=O)N2CCc3ccccc3C2CN2CCCC2)cc1Cl Show InChI InChI=1S/C22H24Cl2N2O/c23-19-8-7-16(13-20(19)24)14-22(27)26-12-9-17-5-1-2-6-18(17)21(26)15-25-10-3-4-11-25/h1-2,5-8,13,21H,3-4,9-12,14-15H2	PDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	0.200	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Zambeletti Research Laboratories Curated by ChEMBL					Assay Description Receptor binding affinity towards opioid receptor kappa				J Med Chem 35: 2970-8 (1992) BindingDB Entry DOI: 10.7270/Q2P26ZR7
					More data for this Ligand-Target Pair
Kappa-type opioid receptor (Cavia porcellus (domestic guinea pig))	BDBM50007159 (2-(3,4-Dichloro-phenyl)-1-(4-pyrrolidin-1-ylmethyl...) Show SMILES Clc1ccc(CC(=O)N2CCc3sccc3C2CN2CCCC2)cc1Cl Show InChI InChI=1S/C20H22Cl2N2OS/c21-16-4-3-14(11-17(16)22)12-20(25)24-9-5-19-15(6-10-26-19)18(24)13-23-7-1-2-8-23/h3-4,6,10-11,18H,1-2,5,7-9,12-13H2	PDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	0.220	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Zambeletti Research Laboratories Curated by ChEMBL					Assay Description Displacement of [3H]-BRL 52537 from opioid receptor kappa site in guinea pig				J Med Chem 34: 2624-33 (1991) BindingDB Entry DOI: 10.7270/Q2CV4GPX
					More data for this Ligand-Target Pair
Kappa-type opioid receptor (Cavia porcellus (domestic guinea pig))	BDBM50453089 (CHEMBL2114225) Show SMILES FC(F)(F)c1ccc(CC(=O)N2CCc3ccccc3[C@H]2CN2CCCC2)cc1 |r| Show InChI InChI=1S/C23H25F3N2O/c24-23(25,26)19-9-7-17(8-10-19)15-22(29)28-14-11-18-5-1-2-6-20(18)21(28)16-27-12-3-4-13-27/h1-2,5-10,21H,3-4,11-16H2/t21-/m1/s1	PDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	0.240	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Zambeletti Research Laboratories Curated by ChEMBL					Assay Description Displacement of [3H]-BRL 52537 from opioid receptor kappa site in guinea pig				J Med Chem 34: 2624-33 (1991) BindingDB Entry DOI: 10.7270/Q2CV4GPX
					More data for this Ligand-Target Pair
Kappa-type opioid receptor (Cavia porcellus (domestic guinea pig))	BDBM50007158 ((S)-2-(3,4-Dichloro-phenyl)-1-(2-pyrrolidin-1-ylme...) Show SMILES Clc1ccc(CC(=O)N2CCCC[C@H]2CN2CCCC2)cc1Cl Show InChI InChI=1S/C18H24Cl2N2O/c19-16-7-6-14(11-17(16)20)12-18(23)22-10-2-1-5-15(22)13-21-8-3-4-9-21/h6-7,11,15H,1-5,8-10,12-13H2/t15-/m0/s1	PDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	PubMed	0.240	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Zambeletti Research Laboratories Curated by ChEMBL					Assay Description Displacement of [3H]-U-69,593 from kappa opioid receptors in guine pig brain (minus cerebellum).				J Med Chem 34: 397-403 (1991) BindingDB Entry DOI: 10.7270/Q23777N1
					More data for this Ligand-Target Pair
Kappa-type opioid receptor (Cavia porcellus (domestic guinea pig))	BDBM50007158 ((S)-2-(3,4-Dichloro-phenyl)-1-(2-pyrrolidin-1-ylme...) Show SMILES Clc1ccc(CC(=O)N2CCCC[C@H]2CN2CCCC2)cc1Cl Show InChI InChI=1S/C18H24Cl2N2O/c19-16-7-6-14(11-17(16)20)12-18(23)22-10-2-1-5-15(22)13-21-8-3-4-9-21/h6-7,11,15H,1-5,8-10,12-13H2/t15-/m0/s1	PDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	PubMed	0.310	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Zambeletti Research Laboratories Curated by ChEMBL					Assay Description Displacement of [3H]-BRL 52537 from opioid receptor kappa site in guinea pig				J Med Chem 34: 2624-33 (1991) BindingDB Entry DOI: 10.7270/Q2CV4GPX
					More data for this Ligand-Target Pair
Kappa-type opioid receptor (Cavia porcellus (domestic guinea pig))	BDBM50008888 ((threo)2-(3,4-Dichloro-phenyl)-1-[2-(1-methyl-pyrr...) Show SMILES CN1CCCC1C1CCCCN1C(=O)Cc1ccc(Cl)c(Cl)c1 Show InChI InChI=1S/C18H24Cl2N2O/c1-21-9-4-6-16(21)17-5-2-3-10-22(17)18(23)12-13-7-8-14(19)15(20)11-13/h7-8,11,16-17H,2-6,9-10,12H2,1H3	PDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	0.330	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Zambeletti Research Laboratories Curated by ChEMBL					Assay Description Displacement of [3H]-U-69,593 from kappa opioid receptors in guine pig brain (minus cerebellum).				J Med Chem 34: 397-403 (1991) BindingDB Entry DOI: 10.7270/Q23777N1
					More data for this Ligand-Target Pair
Kappa-type opioid receptor (Cavia porcellus (domestic guinea pig))	BDBM50008888 ((threo)2-(3,4-Dichloro-phenyl)-1-[2-(1-methyl-pyrr...) Show SMILES CN1CCCC1C1CCCCN1C(=O)Cc1ccc(Cl)c(Cl)c1 Show InChI InChI=1S/C18H24Cl2N2O/c1-21-9-4-6-16(21)17-5-2-3-10-22(17)18(23)12-13-7-8-14(19)15(20)11-13/h7-8,11,16-17H,2-6,9-10,12H2,1H3	PDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	0.330	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Zambeletti Research Laboratories Curated by ChEMBL					Assay Description Displacement of [3H]U-69593 from kappa opioid receptors in guine pig brain (minus cerebellum).				J Med Chem 34: 397-403 (1991) BindingDB Entry DOI: 10.7270/Q23777N1
					More data for this Ligand-Target Pair
Kappa-type opioid receptor (Cavia porcellus (domestic guinea pig))	BDBM50001104 (2-(3,4-Dichloro-phenyl)-1-(3-methyl-1-pyrrolidin-1...) Show SMILES C[C@@H]1Cc2ccccc2C(CN2CCCC2)N1C(=O)Cc1ccc(Cl)c(Cl)c1 Show InChI InChI=1S/C23H26Cl2N2O/c1-16-12-18-6-2-3-7-19(18)22(15-26-10-4-5-11-26)27(16)23(28)14-17-8-9-20(24)21(25)13-17/h2-3,6-9,13,16,22H,4-5,10-12,14-15H2,1H3/t16-,22?/m1/s1	PDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	0.430	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Zambeletti Research Laboratories Curated by ChEMBL					Assay Description Receptor binding affinity towards opioid receptor kappa				J Med Chem 35: 2970-8 (1992) BindingDB Entry DOI: 10.7270/Q2P26ZR7
					More data for this Ligand-Target Pair
Kappa-type opioid receptor (Cavia porcellus (domestic guinea pig))	BDBM50007166 (2-(3,4-Dichloro-phenyl)-1-(7-pyrrolidin-1-ylmethyl...) Show SMILES Clc1ccc(CC(=O)N2CCc3ccsc3C2CN2CCCC2)cc1Cl Show InChI InChI=1S/C20H22Cl2N2OS/c21-16-4-3-14(11-17(16)22)12-19(25)24-9-5-15-6-10-26-20(15)18(24)13-23-7-1-2-8-23/h3-4,6,10-11,18H,1-2,5,7-9,12-13H2	PDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents	PubMed	0.460	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Zambeletti Research Laboratories Curated by ChEMBL					Assay Description Displacement of [3H]-BRL 52537 from opioid receptor kappa site in guinea pig				J Med Chem 34: 2624-33 (1991) BindingDB Entry DOI: 10.7270/Q2CV4GPX
					More data for this Ligand-Target Pair
Kappa-type opioid receptor (Cavia porcellus (domestic guinea pig))	BDBM50007165 (2-(3,4-Dichloro-phenyl)-1-(4-piperidin-1-ylmethyl-...) Show SMILES Clc1ccc(CC(=O)N2CCc3sccc3C2CN2CCCCC2)cc1Cl Show InChI InChI=1S/C21H24Cl2N2OS/c22-17-5-4-15(12-18(17)23)13-21(26)25-10-6-20-16(7-11-27-20)19(25)14-24-8-2-1-3-9-24/h4-5,7,11-12,19H,1-3,6,8-10,13-14H2	PDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	0.470	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Zambeletti Research Laboratories Curated by ChEMBL					Assay Description Displacement of [3H]-BRL 52537 from opioid receptor kappa site in guinea pig				J Med Chem 34: 2624-33 (1991) BindingDB Entry DOI: 10.7270/Q2CV4GPX
					More data for this Ligand-Target Pair
Kappa-type opioid receptor (Cavia porcellus (domestic guinea pig))	BDBM50000278 (2-(3,4-Dichloro-phenyl)-1-(2-piperidin-1-ylmethyl-...) Show SMILES Clc1ccc(CC(=O)N2CCCCC2CN2CCCCC2)cc1Cl Show InChI InChI=1S/C19H26Cl2N2O/c20-17-8-7-15(12-18(17)21)13-19(24)23-11-5-2-6-16(23)14-22-9-3-1-4-10-22/h7-8,12,16H,1-6,9-11,13-14H2	PDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	0.480	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Zambeletti Research Laboratories Curated by ChEMBL					Assay Description Compound was evaluated for its binding affinity against Opioid receptor kappa 1 subtype in guinea pig brain (minus cerebellum)using [3H]-U-69,593 as ...				J Med Chem 34: 397-403 (1991) BindingDB Entry DOI: 10.7270/Q23777N1
					More data for this Ligand-Target Pair
Mu-type opioid receptor (GUINEA PIG)	BDBM50001107 (2-(3,4-Dichloro-phenyl)-1-(5-hydroxy-1-pyrrolidin-...) Show SMILES Oc1cccc2C(CN3CCCC3)N(CCc12)C(=O)Cc1ccc(Cl)c(Cl)c1 Show InChI InChI=1S/C22H24Cl2N2O2/c23-18-7-6-15(12-19(18)24)13-22(28)26-11-8-17-16(4-3-5-21(17)27)20(26)14-25-9-1-2-10-25/h3-7,12,20,27H,1-2,8-11,13-14H2	PDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	0.490	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Zambeletti Research Laboratories Curated by ChEMBL					Assay Description Receptor binding affinity towards opioid receptor mu				J Med Chem 35: 2970-8 (1992) BindingDB Entry DOI: 10.7270/Q2P26ZR7
					More data for this Ligand-Target Pair
Kappa-type opioid receptor (Cavia porcellus (domestic guinea pig))	BDBM50453088 (CHEMBL2114226) Show SMILES CCO.OC(C(O)C(O)=O)C(O)=O.CN(C)CC1N(CCc2ccccc12)C(=O)Cc1ccc(Cl)c(Cl)c1 Show InChI InChI=1S/C20H22Cl2N2O.C4H6O6.C2H6O/c1-23(2)13-19-16-6-4-3-5-15(16)9-10-24(19)20(25)12-14-7-8-17(21)18(22)11-14;5-1(3(7)8)2(6)4(9)10;1-2-3/h3-8,11,19H,9-10,12-13H2,1-2H3;1-2,5-6H,(H,7,8)(H,9,10);3H,2H2,1H3	PDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	PubMed	0.510	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Zambeletti Research Laboratories Curated by ChEMBL					Assay Description Displacement of [3H]-BRL 52537 from opioid receptor kappa site in guinea pig				J Med Chem 34: 2624-33 (1991) BindingDB Entry DOI: 10.7270/Q2CV4GPX
					More data for this Ligand-Target Pair
Kappa-type opioid receptor (Cavia porcellus (domestic guinea pig))	BDBM50000287 (2-(3,4-Dichloro-phenyl)-1-(2-pyrrolidin-1-ylmethyl...) Show SMILES Clc1ccc(CC(=O)N2CCCCC2CN2CCCC2)cc1Cl Show InChI InChI=1S/C18H24Cl2N2O/c19-16-7-6-14(11-17(16)20)12-18(23)22-10-2-1-5-15(22)13-21-8-3-4-9-21/h6-7,11,15H,1-5,8-10,12-13H2	PDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	PubMed	0.530	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Zambeletti Research Laboratories Curated by ChEMBL					Assay Description Compound was evaluated for its binding affinity against Opioid receptor kappa 1 subtype in guinea pig brain (minus cerebellum) .using [3H]-U-69,593 a...				J Med Chem 34: 397-403 (1991) BindingDB Entry DOI: 10.7270/Q23777N1
					More data for this Ligand-Target Pair
Kappa-type opioid receptor (Cavia porcellus (domestic guinea pig))	BDBM50008895 (1-(2-Pyrrolidin-1-ylmethyl-piperidin-1-yl)-2-(4-tr...) Show SMILES FC(F)(F)c1ccc(CC(=O)N2CCCCC2CN2CCCC2)cc1 Show InChI InChI=1S/C19H25F3N2O/c20-19(21,22)16-8-6-15(7-9-16)13-18(25)24-12-2-1-5-17(24)14-23-10-3-4-11-23/h6-9,17H,1-5,10-14H2	PDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	PubMed	0.570	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Zambeletti Research Laboratories Curated by ChEMBL					Assay Description Displacement of [3H]-U-69,593 from kappa opioid receptors in guine pig brain (minus cerebellum).				J Med Chem 34: 397-403 (1991) BindingDB Entry DOI: 10.7270/Q23777N1
					More data for this Ligand-Target Pair
Kappa-type opioid receptor (Cavia porcellus (domestic guinea pig))	BDBM50008895 (1-(2-Pyrrolidin-1-ylmethyl-piperidin-1-yl)-2-(4-tr...) Show SMILES FC(F)(F)c1ccc(CC(=O)N2CCCCC2CN2CCCC2)cc1 Show InChI InChI=1S/C19H25F3N2O/c20-19(21,22)16-8-6-15(7-9-16)13-18(25)24-12-2-1-5-17(24)14-23-10-3-4-11-23/h6-9,17H,1-5,10-14H2	PDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	PubMed	0.570	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Zambeletti Research Laboratories Curated by ChEMBL					Assay Description Displacement of [3H]U-69593 from kappa opioid receptors in guine pig brain (minus cerebellum).				J Med Chem 34: 397-403 (1991) BindingDB Entry DOI: 10.7270/Q23777N1
					More data for this Ligand-Target Pair
Kappa-type opioid receptor (Cavia porcellus (domestic guinea pig))	BDBM50001105 (2-(3,4-Dichloro-phenyl)-1-(4-methyl-1-pyrrolidin-1...) Show SMILES C[C@@H]1CN(C(CN2CCCC2)c2ccccc12)C(=O)Cc1ccc(Cl)c(Cl)c1 Show InChI InChI=1S/C23H26Cl2N2O/c1-16-14-27(23(28)13-17-8-9-20(24)21(25)12-17)22(15-26-10-4-5-11-26)19-7-3-2-6-18(16)19/h2-3,6-9,12,16,22H,4-5,10-11,13-15H2,1H3/t16-,22?/m1/s1	PDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	0.600	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Zambeletti Research Laboratories Curated by ChEMBL					Assay Description Receptor binding affinity towards opioid receptor kappa				J Med Chem 35: 2970-8 (1992) BindingDB Entry DOI: 10.7270/Q2P26ZR7
					More data for this Ligand-Target Pair
Kappa-type opioid receptor (Cavia porcellus (domestic guinea pig))	BDBM50007167 (1-(4-Piperidin-1-ylmethyl-6,7-dihydro-4H-thieno[3,...) Show SMILES FC(F)(F)c1ccc(CC(=O)N2CCc3sccc3C2CN2CCCCC2)cc1 Show InChI InChI=1S/C22H25F3N2OS/c23-22(24,25)17-6-4-16(5-7-17)14-21(28)27-12-8-20-18(9-13-29-20)19(27)15-26-10-2-1-3-11-26/h4-7,9,13,19H,1-3,8,10-12,14-15H2	PDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	0.600	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Zambeletti Research Laboratories Curated by ChEMBL					Assay Description Displacement of [3H]-BRL 52537 from opioid receptor kappa site in guinea pig				J Med Chem 34: 2624-33 (1991) BindingDB Entry DOI: 10.7270/Q2CV4GPX
					More data for this Ligand-Target Pair
Kappa-type opioid receptor (Cavia porcellus (domestic guinea pig))	BDBM50007157 ((-)-1-(1-Piperidin-1-ylmethyl-3,4-dihydro-1H-isoqu...) Show SMILES FC(F)(F)c1ccc(CC(=O)N2CCc3ccccc3C2CN2CCCCC2)cc1 Show InChI InChI=1S/C24H27F3N2O/c25-24(26,27)20-10-8-18(9-11-20)16-23(30)29-15-12-19-6-2-3-7-21(19)22(29)17-28-13-4-1-5-14-28/h2-3,6-11,22H,1,4-5,12-17H2	PDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	0.620	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Zambeletti Research Laboratories Curated by ChEMBL					Assay Description Displacement of [3H]-BRL 52537 from opioid receptor kappa site in guinea pig				J Med Chem 34: 2624-33 (1991) BindingDB Entry DOI: 10.7270/Q2CV4GPX
					More data for this Ligand-Target Pair
Kappa-type opioid receptor (Cavia porcellus (domestic guinea pig))	BDBM50007164 ((S)-1-(2-Pyrrolidin-1-ylmethyl-piperidin-1-yl)-2-(...) Show SMILES FC(F)(F)c1ccc(CC(=O)N2CCCC[C@H]2CN2CCCC2)cc1 Show InChI InChI=1S/C19H25F3N2O/c20-19(21,22)16-8-6-15(7-9-16)13-18(25)24-12-2-1-5-17(24)14-23-10-3-4-11-23/h6-9,17H,1-5,10-14H2/t17-/m0/s1	PDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	PubMed	0.640	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Zambeletti Research Laboratories Curated by ChEMBL					Assay Description Displacement of [3H]-BRL 52537 from opioid receptor kappa site in guinea pig				J Med Chem 34: 2624-33 (1991) BindingDB Entry DOI: 10.7270/Q2CV4GPX
					More data for this Ligand-Target Pair
Kappa-type opioid receptor (Cavia porcellus (domestic guinea pig))	BDBM50452995 (CHEMBL2111856) Show SMILES CN(C)C[C@@H]1CCCCN1C(=O)Cc1ccc(Cl)c(Cl)c1 |r| Show InChI InChI=1S/C16H22Cl2N2O/c1-19(2)11-13-5-3-4-8-20(13)16(21)10-12-6-7-14(17)15(18)9-12/h6-7,9,13H,3-5,8,10-11H2,1-2H3/t13-/m0/s1	PDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	0.700	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Zambeletti Research Laboratories Curated by ChEMBL					Assay Description Displacement of [3H]-U-69,593 from kappa opioid receptors in guine pig brain (minus cerebellum).				J Med Chem 34: 397-403 (1991) BindingDB Entry DOI: 10.7270/Q23777N1
					More data for this Ligand-Target Pair
Kappa-type opioid receptor (Cavia porcellus (domestic guinea pig))	BDBM50008897 (2-(4-Bromo-phenyl)-1-(2-pyrrolidin-1-ylmethyl-pipe...) Show SMILES Brc1ccc(CC(=O)N2CCCCC2CN2CCCC2)cc1 Show InChI InChI=1S/C18H25BrN2O/c19-16-8-6-15(7-9-16)13-18(22)21-12-2-1-5-17(21)14-20-10-3-4-11-20/h6-9,17H,1-5,10-14H2	PDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	0.840	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Zambeletti Research Laboratories Curated by ChEMBL					Assay Description Displacement of [3H]-U-69,593 from kappa opioid receptors in guine pig brain (minus cerebellum).				J Med Chem 34: 397-403 (1991) BindingDB Entry DOI: 10.7270/Q23777N1
					More data for this Ligand-Target Pair
Kappa-type opioid receptor (Cavia porcellus (domestic guinea pig))	BDBM50000296 (CHEMBL441765 | CHEMBL482811 | U-50488H | US1149237...) Show SMILES CN([C@@H]1CCCC[C@H]1N1CCCC1)C(=O)Cc1ccc(Cl)c(Cl)c1 |r| Show InChI InChI=1S/C19H26Cl2N2O/c1-22(19(24)13-14-8-9-15(20)16(21)12-14)17-6-2-3-7-18(17)23-10-4-5-11-23/h8-9,12,17-18H,2-7,10-11,13H2,1H3/t17-,18-/m1/s1	PDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase CHEMBL KEGG PC cid PC sid UniChem Patents Similars	PubMed	0.970	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Zambeletti Research Laboratories Curated by ChEMBL					Assay Description Displacement of [3H]-U-69,593 from kappa opioid receptors in guine pig brain (minus cerebellum).				J Med Chem 34: 397-403 (1991) BindingDB Entry DOI: 10.7270/Q23777N1
					More data for this Ligand-Target Pair
Kappa-type opioid receptor (Cavia porcellus (domestic guinea pig))	BDBM50008898 (1-(2-Pyrrolidin-1-ylmethyl-piperidin-1-yl)-2-(3-tr...) Show SMILES FC(F)(F)c1cccc(CC(=O)N2CCCCC2CN2CCCC2)c1 Show InChI InChI=1S/C19H25F3N2O/c20-19(21,22)16-7-5-6-15(12-16)13-18(25)24-11-2-1-8-17(24)14-23-9-3-4-10-23/h5-7,12,17H,1-4,8-11,13-14H2	PDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	1.10	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Zambeletti Research Laboratories Curated by ChEMBL					Assay Description Displacement of [3H]-U-69,593 from kappa opioid receptors in guine pig brain (minus cerebellum).				J Med Chem 34: 397-403 (1991) BindingDB Entry DOI: 10.7270/Q23777N1
					More data for this Ligand-Target Pair
Kappa-type opioid receptor (Cavia porcellus (domestic guinea pig))	BDBM50008899 (2-(3,4-Dichloro-phenyl)-1-(2-diethylaminomethyl-pi...) Show SMILES CCN(CC)CC1CCCCN1C(=O)Cc1ccc(Cl)c(Cl)c1 Show InChI InChI=1S/C18H26Cl2N2O/c1-3-21(4-2)13-15-7-5-6-10-22(15)18(23)12-14-8-9-16(19)17(20)11-14/h8-9,11,15H,3-7,10,12-13H2,1-2H3	PDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	1.30	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Zambeletti Research Laboratories Curated by ChEMBL					Assay Description Displacement of [3H]-U-69,593 from kappa opioid receptors in guine pig brain (minus cerebellum).				J Med Chem 34: 397-403 (1991) BindingDB Entry DOI: 10.7270/Q23777N1
					More data for this Ligand-Target Pair
Kappa-type opioid receptor (Cavia porcellus (domestic guinea pig))	BDBM50000267 (2-(3,4-Dichloro-phenyl)-1-(2-dimethylaminomethyl-p...) Show SMILES CN(C)CC1CCCCN1C(=O)Cc1ccc(Cl)c(Cl)c1 Show InChI InChI=1S/C16H22Cl2N2O/c1-19(2)11-13-5-3-4-8-20(13)16(21)10-12-6-7-14(17)15(18)9-12/h6-7,9,13H,3-5,8,10-11H2,1-2H3	PDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	1.40	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Zambeletti Research Laboratories Curated by ChEMBL					Assay Description Compound was evaluated for its binding affinity against Opioid receptor kappa 1 subtype in guinea pig brain (minus cerebellum)using [3H]-U-69,593 as ...				J Med Chem 34: 397-403 (1991) BindingDB Entry DOI: 10.7270/Q23777N1
					More data for this Ligand-Target Pair
Kappa-type opioid receptor (Cavia porcellus (domestic guinea pig))	BDBM50008892 (2-(4-Chloro-phenyl)-1-(2-pyrrolidin-1-ylmethyl-pip...) Show SMILES Clc1ccc(CC(=O)N2CCCCC2CN2CCCC2)cc1 Show InChI InChI=1S/C18H25ClN2O/c19-16-8-6-15(7-9-16)13-18(22)21-12-2-1-5-17(21)14-20-10-3-4-11-20/h6-9,17H,1-5,10-14H2	PDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	1.70	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Zambeletti Research Laboratories Curated by ChEMBL					Assay Description Displacement of [3H]-U-69,593 from kappa opioid receptors in guine pig brain (minus cerebellum).				J Med Chem 34: 397-403 (1991) BindingDB Entry DOI: 10.7270/Q23777N1
					More data for this Ligand-Target Pair
Kappa-type opioid receptor (Cavia porcellus (domestic guinea pig))	BDBM50008893 (2-(3,4-Dimethyl-phenyl)-1-(2-pyrrolidin-1-ylmethyl...) Show SMILES Cc1ccc(CC(=O)N2CCCCC2CN2CCCC2)cc1C Show InChI InChI=1S/C20H30N2O/c1-16-8-9-18(13-17(16)2)14-20(23)22-12-4-3-7-19(22)15-21-10-5-6-11-21/h8-9,13,19H,3-7,10-12,14-15H2,1-2H3	PDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	1.80	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Zambeletti Research Laboratories Curated by ChEMBL					Assay Description Displacement of [3H]-U-69,593 from kappa opioid receptors in guine pig brain (minus cerebellum).				J Med Chem 34: 397-403 (1991) BindingDB Entry DOI: 10.7270/Q23777N1
					More data for this Ligand-Target Pair
Kappa-type opioid receptor (Cavia porcellus (domestic guinea pig))	BDBM50000296 (CHEMBL441765 | CHEMBL482811 | U-50488H | US1149237...) Show SMILES CN([C@@H]1CCCC[C@H]1N1CCCC1)C(=O)Cc1ccc(Cl)c(Cl)c1 |r| Show InChI InChI=1S/C19H26Cl2N2O/c1-22(19(24)13-14-8-9-15(20)16(21)12-14)17-6-2-3-7-18(17)23-10-4-5-11-23/h8-9,12,17-18H,2-7,10-11,13H2,1H3/t17-,18-/m1/s1	PDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase CHEMBL KEGG PC cid PC sid UniChem Patents Similars	PubMed	2.20	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Zambeletti Research Laboratories Curated by ChEMBL					Assay Description Receptor binding affinity towards opioid receptor kappa				J Med Chem 35: 2970-8 (1992) BindingDB Entry DOI: 10.7270/Q2P26ZR7
					More data for this Ligand-Target Pair
Kappa-type opioid receptor (Cavia porcellus (domestic guinea pig))	BDBM50000296 (CHEMBL441765 | CHEMBL482811 | U-50488H | US1149237...) Show SMILES CN([C@@H]1CCCC[C@H]1N1CCCC1)C(=O)Cc1ccc(Cl)c(Cl)c1 |r| Show InChI InChI=1S/C19H26Cl2N2O/c1-22(19(24)13-14-8-9-15(20)16(21)12-14)17-6-2-3-7-18(17)23-10-4-5-11-23/h8-9,12,17-18H,2-7,10-11,13H2,1H3/t17-,18-/m1/s1	PDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase CHEMBL KEGG PC cid PC sid UniChem Patents Similars	PubMed	2.20	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Zambeletti Research Laboratories Curated by ChEMBL					Assay Description Displacement of [3H]-BRL 52537 from opioid receptor kappa site in guinea pig				J Med Chem 34: 2624-33 (1991) BindingDB Entry DOI: 10.7270/Q2CV4GPX
					More data for this Ligand-Target Pair
Kappa-type opioid receptor (Cavia porcellus (domestic guinea pig))	BDBM50001106 (2-(3,4-Dichloro-phenyl)-1-(4,4-dimethyl-1-pyrrolid...) Show SMILES CC1(C)CN(C(CN2CCCC2)c2ccccc12)C(=O)Cc1ccc(Cl)c(Cl)c1 Show InChI InChI=1S/C24H28Cl2N2O/c1-24(2)16-28(23(29)14-17-9-10-20(25)21(26)13-17)22(15-27-11-5-6-12-27)18-7-3-4-8-19(18)24/h3-4,7-10,13,22H,5-6,11-12,14-16H2,1-2H3	PDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	2.30	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Zambeletti Research Laboratories Curated by ChEMBL					Assay Description Receptor binding affinity towards opioid receptor kappa				J Med Chem 35: 2970-8 (1992) BindingDB Entry DOI: 10.7270/Q2P26ZR7
					More data for this Ligand-Target Pair
Mu-type opioid receptor (GUINEA PIG)	BDBM50000092 ((-)-(etorphine) | (-)-morphine | (1S,5R,13R,14S)-1...) Show SMILES CN1CC[C@@]23[C@H]4Oc5c2c(C[C@@H]1[C@@H]3C=C[C@@H]4O)ccc5O |r,c:16,TLB:13:12:8.9.10:3.2.1| Show InChI InChI=1S/C17H19NO3/c1-18-7-6-17-10-3-5-13(20)16(17)21-15-12(19)4-2-9(14(15)17)8-11(10)18/h2-5,10-11,13,16,19-20H,6-8H2,1H3/t10-,11+,13-,16-,17-/m0/s1	PDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase CHEMBL DrugBank KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	PubMed	3.30	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Zambeletti Research Laboratories Curated by ChEMBL					Assay Description Receptor binding affinity towards opioid receptor mu				J Med Chem 35: 2970-8 (1992) BindingDB Entry DOI: 10.7270/Q2P26ZR7
					More data for this Ligand-Target Pair
Mu-type opioid receptor (GUINEA PIG)	BDBM50000092 ((-)-(etorphine) | (-)-morphine | (1S,5R,13R,14S)-1...) Show SMILES CN1CC[C@@]23[C@H]4Oc5c2c(C[C@@H]1[C@@H]3C=C[C@@H]4O)ccc5O |r,c:16,TLB:13:12:8.9.10:3.2.1| Show InChI InChI=1S/C17H19NO3/c1-18-7-6-17-10-3-5-13(20)16(17)21-15-12(19)4-2-9(14(15)17)8-11(10)18/h2-5,10-11,13,16,19-20H,6-8H2,1H3/t10-,11+,13-,16-,17-/m0/s1	PDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase CHEMBL DrugBank KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	PubMed	3.30	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Zambeletti Research Laboratories Curated by ChEMBL					Assay Description Displacement of [3H]-DAGO from mu opioid receptors in guinea pig brain (minus cerebellum).				J Med Chem 34: 397-403 (1991) BindingDB Entry DOI: 10.7270/Q23777N1
					More data for this Ligand-Target Pair
Mu-type opioid receptor (GUINEA PIG)	BDBM50000092 ((-)-(etorphine) | (-)-morphine | (1S,5R,13R,14S)-1...) Show SMILES CN1CC[C@@]23[C@H]4Oc5c2c(C[C@@H]1[C@@H]3C=C[C@@H]4O)ccc5O |r,c:16,TLB:13:12:8.9.10:3.2.1| Show InChI InChI=1S/C17H19NO3/c1-18-7-6-17-10-3-5-13(20)16(17)21-15-12(19)4-2-9(14(15)17)8-11(10)18/h2-5,10-11,13,16,19-20H,6-8H2,1H3/t10-,11+,13-,16-,17-/m0/s1	PDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase CHEMBL DrugBank KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	PubMed	3.30	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Zambeletti Research Laboratories Curated by ChEMBL					Assay Description Affinity for opioid receptor mu sites				J Med Chem 34: 2624-33 (1991) BindingDB Entry DOI: 10.7270/Q2CV4GPX
					More data for this Ligand-Target Pair
Kappa-type opioid receptor (Cavia porcellus (domestic guinea pig))	BDBM50008894 (1-(2-Pyrrolidin-1-ylmethyl-piperidin-1-yl)-2-p-tol...) Show SMILES Cc1ccc(CC(=O)N2CCCCC2CN2CCCC2)cc1 Show InChI InChI=1S/C19H28N2O/c1-16-7-9-17(10-8-16)14-19(22)21-13-3-2-6-18(21)15-20-11-4-5-12-20/h7-10,18H,2-6,11-15H2,1H3	PDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	3.80	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Zambeletti Research Laboratories Curated by ChEMBL					Assay Description Displacement of [3H]-U-69,593 from kappa opioid receptors in guine pig brain (minus cerebellum).				J Med Chem 34: 397-403 (1991) BindingDB Entry DOI: 10.7270/Q23777N1
					More data for this Ligand-Target Pair
Delta-type opioid receptor (Homo sapiens (Human))	BDBM50001107 (2-(3,4-Dichloro-phenyl)-1-(5-hydroxy-1-pyrrolidin-...) Show SMILES Oc1cccc2C(CN3CCCC3)N(CCc12)C(=O)Cc1ccc(Cl)c(Cl)c1 Show InChI InChI=1S/C22H24Cl2N2O2/c23-18-7-6-15(12-19(18)24)13-22(28)26-11-8-17-16(4-3-5-21(17)27)20(26)14-25-9-1-2-10-25/h3-7,12,20,27H,1-2,8-11,13-14H2	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	7.10	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Zambeletti Research Laboratories Curated by ChEMBL					Assay Description Receptor binding affinity towards opioid receptor delta				J Med Chem 35: 2970-8 (1992) BindingDB Entry DOI: 10.7270/Q2P26ZR7
					More data for this Ligand-Target Pair
Kappa-type opioid receptor (Cavia porcellus (domestic guinea pig))	BDBM50008896 (1-(2-Pyrrolidin-1-ylmethyl-piperidin-1-yl)-2-(2-tr...) Show SMILES FC(F)(F)c1ccccc1CC(=O)N1CCCCC1CN1CCCC1 Show InChI InChI=1S/C19H25F3N2O/c20-19(21,22)17-9-2-1-7-15(17)13-18(25)24-12-4-3-8-16(24)14-23-10-5-6-11-23/h1-2,7,9,16H,3-6,8,10-14H2	PDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	8.5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Zambeletti Research Laboratories Curated by ChEMBL					Assay Description Displacement of [3H]-U-69,593 from kappa opioid receptors in guine pig brain (minus cerebellum).				J Med Chem 34: 397-403 (1991) BindingDB Entry DOI: 10.7270/Q23777N1
					More data for this Ligand-Target Pair
Mu-type opioid receptor (GUINEA PIG)	BDBM50453089 (CHEMBL2114225) Show SMILES FC(F)(F)c1ccc(CC(=O)N2CCc3ccccc3[C@H]2CN2CCCC2)cc1 |r| Show InChI InChI=1S/C23H25F3N2O/c24-23(25,26)19-9-7-17(8-10-19)15-22(29)28-14-11-18-5-1-2-6-20(18)21(28)16-27-12-3-4-13-27/h1-2,5-10,21H,3-4,11-16H2/t21-/m1/s1	PDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	11	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Zambeletti Research Laboratories Curated by ChEMBL					Assay Description Affinity for opioid receptor mu sites				J Med Chem 34: 2624-33 (1991) BindingDB Entry DOI: 10.7270/Q2CV4GPX
					More data for this Ligand-Target Pair
Mu-type opioid receptor (GUINEA PIG)	BDBM50001104 (2-(3,4-Dichloro-phenyl)-1-(3-methyl-1-pyrrolidin-1...) Show SMILES C[C@@H]1Cc2ccccc2C(CN2CCCC2)N1C(=O)Cc1ccc(Cl)c(Cl)c1 Show InChI InChI=1S/C23H26Cl2N2O/c1-16-12-18-6-2-3-7-19(18)22(15-26-10-4-5-11-26)27(16)23(28)14-17-8-9-20(24)21(25)13-17/h2-3,6-9,13,16,22H,4-5,10-12,14-15H2,1H3/t16-,22?/m1/s1	PDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	11	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Zambeletti Research Laboratories Curated by ChEMBL					Assay Description Receptor binding affinity towards opioid receptor mu				J Med Chem 35: 2970-8 (1992) BindingDB Entry DOI: 10.7270/Q2P26ZR7
					More data for this Ligand-Target Pair
Kappa-type opioid receptor (Cavia porcellus (domestic guinea pig))	BDBM50452994 (CHEMBL2111857) Show SMILES Clc1ccc(CC(=O)N2CCCC[C@@H]2CN2CCCC2)cc1Cl |r| Show InChI InChI=1S/C18H24Cl2N2O/c19-16-7-6-14(11-17(16)20)12-18(23)22-10-2-1-5-15(22)13-21-8-3-4-9-21/h6-7,11,15H,1-5,8-10,12-13H2/t15-/m1/s1	PDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Similars	PubMed	15	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Zambeletti Research Laboratories Curated by ChEMBL					Assay Description Displacement of [3H]-U-69,593 from kappa opioid receptors in guine pig brain (minus cerebellum).				J Med Chem 34: 397-403 (1991) BindingDB Entry DOI: 10.7270/Q23777N1
					More data for this Ligand-Target Pair
Kappa-type opioid receptor (Cavia porcellus (domestic guinea pig))	BDBM50008891 (2-(4-Fluoro-phenyl)-1-(2-pyrrolidin-1-ylmethyl-pip...) Show SMILES Fc1ccc(CC(=O)N2CCCCC2CN2CCCC2)cc1 Show InChI InChI=1S/C18H25FN2O/c19-16-8-6-15(7-9-16)13-18(22)21-12-2-1-5-17(21)14-20-10-3-4-11-20/h6-9,17H,1-5,10-14H2	PDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	15	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Zambeletti Research Laboratories Curated by ChEMBL					Assay Description Displacement of [3H]-U-69,593 from kappa opioid receptors in guine pig brain (minus cerebellum).				J Med Chem 34: 397-403 (1991) BindingDB Entry DOI: 10.7270/Q23777N1
					More data for this Ligand-Target Pair
Mu-type opioid receptor (GUINEA PIG)	BDBM50001108 (2-(3,4-Dichloro-phenyl)-1-(1-pyrrolidin-1-ylmethyl...) Show SMILES Clc1ccc(CC(=O)N2CCc3ccccc3C2CN2CCCC2)cc1Cl Show InChI InChI=1S/C22H24Cl2N2O/c23-19-8-7-16(13-20(19)24)14-22(27)26-12-9-17-5-1-2-6-18(17)21(26)15-25-10-3-4-11-25/h1-2,5-8,13,21H,3-4,9-12,14-15H2	PDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	30	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Zambeletti Research Laboratories Curated by ChEMBL					Assay Description Affinity for opioid receptor mu sites				J Med Chem 34: 2624-33 (1991) BindingDB Entry DOI: 10.7270/Q2CV4GPX
					More data for this Ligand-Target Pair
Mu-type opioid receptor (GUINEA PIG)	BDBM50001108 (2-(3,4-Dichloro-phenyl)-1-(1-pyrrolidin-1-ylmethyl...) Show SMILES Clc1ccc(CC(=O)N2CCc3ccccc3C2CN2CCCC2)cc1Cl Show InChI InChI=1S/C22H24Cl2N2O/c23-19-8-7-16(13-20(19)24)14-22(27)26-12-9-17-5-1-2-6-18(17)21(26)15-25-10-3-4-11-25/h1-2,5-8,13,21H,3-4,9-12,14-15H2	PDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	30	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Zambeletti Research Laboratories Curated by ChEMBL					Assay Description Receptor binding affinity towards opioid receptor mu				J Med Chem 35: 2970-8 (1992) BindingDB Entry DOI: 10.7270/Q2P26ZR7
					More data for this Ligand-Target Pair
Delta-type opioid receptor (Homo sapiens (Human))	BDBM50001104 (2-(3,4-Dichloro-phenyl)-1-(3-methyl-1-pyrrolidin-1...) Show SMILES C[C@@H]1Cc2ccccc2C(CN2CCCC2)N1C(=O)Cc1ccc(Cl)c(Cl)c1 Show InChI InChI=1S/C23H26Cl2N2O/c1-16-12-18-6-2-3-7-19(18)22(15-26-10-4-5-11-26)27(16)23(28)14-17-8-9-20(24)21(25)13-17/h2-3,6-9,13,16,22H,4-5,10-12,14-15H2,1H3/t16-,22?/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	44	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Zambeletti Research Laboratories Curated by ChEMBL					Assay Description Receptor binding affinity towards opioid receptor delta				J Med Chem 35: 2970-8 (1992) BindingDB Entry DOI: 10.7270/Q2P26ZR7
					More data for this Ligand-Target Pair
Mu-type opioid receptor (GUINEA PIG)	BDBM50007166 (2-(3,4-Dichloro-phenyl)-1-(7-pyrrolidin-1-ylmethyl...) Show SMILES Clc1ccc(CC(=O)N2CCc3ccsc3C2CN2CCCC2)cc1Cl Show InChI InChI=1S/C20H22Cl2N2OS/c21-16-4-3-14(11-17(16)22)12-19(25)24-9-5-15-6-10-26-20(15)18(24)13-23-7-1-2-8-23/h3-4,6,10-11,18H,1-2,5,7-9,12-13H2	PDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents	PubMed	47	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Zambeletti Research Laboratories Curated by ChEMBL					Assay Description Affinity for opioid receptor mu sites				J Med Chem 34: 2624-33 (1991) BindingDB Entry DOI: 10.7270/Q2CV4GPX
					More data for this Ligand-Target Pair
Mu-type opioid receptor (GUINEA PIG)	BDBM50007159 (2-(3,4-Dichloro-phenyl)-1-(4-pyrrolidin-1-ylmethyl...) Show SMILES Clc1ccc(CC(=O)N2CCc3sccc3C2CN2CCCC2)cc1Cl Show InChI InChI=1S/C20H22Cl2N2OS/c21-16-4-3-14(11-17(16)22)12-20(25)24-9-5-19-15(6-10-26-19)18(24)13-23-7-1-2-8-23/h3-4,6,10-11,18H,1-2,5,7-9,12-13H2	PDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	47	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Zambeletti Research Laboratories Curated by ChEMBL					Assay Description Affinity for opioid receptor mu sites				J Med Chem 34: 2624-33 (1991) BindingDB Entry DOI: 10.7270/Q2CV4GPX
					More data for this Ligand-Target Pair
Mu-type opioid receptor (GUINEA PIG)	BDBM50001105 (2-(3,4-Dichloro-phenyl)-1-(4-methyl-1-pyrrolidin-1...) Show SMILES C[C@@H]1CN(C(CN2CCCC2)c2ccccc12)C(=O)Cc1ccc(Cl)c(Cl)c1 Show InChI InChI=1S/C23H26Cl2N2O/c1-16-14-27(23(28)13-17-8-9-20(24)21(25)12-17)22(15-26-10-4-5-11-26)19-7-3-2-6-18(16)19/h2-3,6-9,12,16,22H,4-5,10-11,13-15H2,1H3/t16-,22?/m1/s1	PDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	57	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Zambeletti Research Laboratories Curated by ChEMBL					Assay Description Receptor binding affinity towards opioid receptor mu				J Med Chem 35: 2970-8 (1992) BindingDB Entry DOI: 10.7270/Q2P26ZR7
					More data for this Ligand-Target Pair
Kappa-type opioid receptor (Cavia porcellus (domestic guinea pig))	BDBM50007163 (2-(3,4-Dichloro-phenyl)-1-(1-pyrrolidin-1-ylmethyl...) Show SMILES Clc1ccc(CC(=O)N2CCc3[nH]c4ccccc4c3C2CN2CCCC2)cc1Cl Show InChI InChI=1S/C24H25Cl2N3O/c25-18-8-7-16(13-19(18)26)14-23(30)29-12-9-21-24(17-5-1-2-6-20(17)27-21)22(29)15-28-10-3-4-11-28/h1-2,5-8,13,22,27H,3-4,9-12,14-15H2	PDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	100	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Zambeletti Research Laboratories Curated by ChEMBL					Assay Description Displacement of [3H]-BRL 52537 from opioid receptor kappa site in guinea pig				J Med Chem 34: 2624-33 (1991) BindingDB Entry DOI: 10.7270/Q2CV4GPX
					More data for this Ligand-Target Pair

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